Suggested is an anti-dandruff composition comprising (a) 1-acetoxychavicol acetate according to formula (I) or an extract comprising the same, and (b) at least one vegetable oil for use in treating or preventing Malassezia induced dandruff formation and/or Malassezia induced itching of the skin.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
Suggested is a preparation, comprising or consisting of (a) specific oleanol glycosides, their salts or an extract containing oleanol glycosides and (b) inorganic salts or mineral substances.
Suggested is an enzymatic process for preparing hydroxycinnamic acid amides comprising or consisting of the following steps:
(i) providing at least one hydroxycinnamic acid ester (component a);
(ii) providing at least one amine (component b);
(iii) providing at least one source of Pyrobaculum calidifontis VA1 esterase (component c);
(iv) providing an aqueous buffer (component d)
(v) blending components (a) to (d) to form a reaction mixture;
(vi) adjusting the pH to a value above 7;
(vii) incubating the reaction mixture at a temperature ranging from about 25 to about 90° C. for preferably at least 5 minutes; and
(viii) collecting the hydroxycinnamic acid amides thus obtained from the reaction mixture.
Suggested are new microbial glycolipids of formula (I), wherein X stands for nitrogen or oxygen; R1 represents hydrogen, —CO-Alkyl, —CO-Aryl, —CO—N-Alkyl, —CO—N-Aryl, SO2-Alkyl, SO2-Aryl, —CO(CH2)n COOH with n=1 to 4, or an amino acid; R2 represents —OH or —O-Glucose; R3 represents hydrogen or —OH; n 1 or 2 has the meaning of a single or double bond.
A61Q 17/00 - Barrier preparationsPreparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
C07H 1/00 - Processes for the preparation of sugar derivatives
C07H 15/04 - Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of a saccharide radical
C07H 15/10 - Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of a saccharide radical containing unsaturated carbon-to-carbon bonds
The present invention refers to the area of 5-deoxyflavonoids and concerns new and effective antioxidants of natural origin. Said compounds can be added to cosmetic, detergent, agrochemical, beverage or food, and aqueous composition to substantially increase oxidative stability at very low concentrations.
A01N 25/22 - Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of applicationSubstances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
A01N 65/20 - Fabaceae or Leguminosae [Pea or Legume family], e.g. pea, lentil, soybean, clover, acacia, honey locust, derris or millettia
A23L 3/3472 - Compounds of undetermined constitution obtained from animals or plants
Suggested is the use of a preservative composition comprising or consisting of hederagenin glycosides, said hederagenin glycosides being selected from at least one monodesmosidic hederagenin-3-glycoside according to formula (I), A, B and C.
A61Q 17/00 - Barrier preparationsPreparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations
A23L 2/44 - Preservation of non-alcoholic beverages by adding preservatives
A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
A61K 31/704 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin, digitoxin
Suggested is a method for improving antimicrobial stability of a composition comprising or consisting of glycolipids, said glycolipids being selected from at least one ustilagic acid according to formula (I)-(III) or compounds 1-6.
A01N 43/16 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom six-membered rings with oxygen as the ring hetero atom
A01P 1/00 - DisinfectantsAntimicrobial compounds or mixtures thereof
Disclosed is the use of a preservative composition comprising or consisting of glycolipids, said glycolipids being selected from at least one spirostan-3-glycosides according to formula (I), A to D.
A61Q 17/00 - Barrier preparationsPreparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
Suggested is a broad variety of compounds extracted from natural sources as sweeteners and sweetness enhancers, particular for sucrose and rebaudiosides.
Suggested is an extract of Persea, in particular Persea americana (Avocado) comprising at least 90 wt.-percent avocado polyols and preferably at least 95 wt.-percent avocadene, obtainable or obtained according to the following steps: (a) providing a source of Persea; (b) subjecting said source of Persea to an extraction step using organic solvents to obtain a first extract; (c) subjecting said first extract to saponification to obtain a second extract; (d) adding a source of calcium to said second extract to precipitate calcium soaps; (e) subjecting the product of step (d) to a separation step to obtain a third extract and said precipitated calcium salts; and optionally (f) subjecting said third extract to purification.
Suggested are new microbial glycolipids of formula (I), wherein X stands for nitrogen or oxygen; R1222nnCOOH with n=1 to 4, or an amino acid; R2represents -OH or -O-Glucose; R3 represents hydrogen or –OH; n 1 or 2 has the meaning of a single or double bond.
C07H 15/06 - Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of a saccharide radical being a hydroxyalkyl group esterified by a fatty acid
C07H 15/10 - Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of a saccharide radical containing unsaturated carbon-to-carbon bonds
Suggested are preparations, comprising or consisting of (a) C-methyl flavonoids, a salt of C-methyl flavonoids and/or an extract containing C-methyl flavonoids, and (b) at least one inorganic salt or mineral substance.
A23G 3/50 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
A23G 4/06 - Chewing gum characterised by the composition
1. Suggested is the use of compounds according to Formula (I) and/or Formula (II) as sweetener and/or sweetness enhancer and/or masking agent for the unpleasant taste of another sweetener.
A23G 3/50 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
A23G 4/06 - Chewing gum characterised by the composition
Suggested is the use of at least one, preferably two, three, four or more compounds according to Formula (I) wherein R1 = H or OH R2 = H or Apiose R3 = H or Rhamnose as sweetener and/or sweetness enhancer and/or masking agent for the unpleasant taste of another sweetener.
A23G 3/50 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof characterised by shape, structure or physical form, e.g. products with supported structure
A23G 4/06 - Chewing gum characterised by the composition
PerseaPerseaPersea Persea to an extraction step using organic solvents to obtain a first extract; (c) subjecting said first extract to saponification to obtain a second extract; (d) adding a source of calcium to said second extract to precipitate calcium soaps; (e) subjecting the product of step (d) to a separation step to obtain a third extract and said precipitated calcium salts; and optionally (f) subjecting said third extract to purification.
Suggested are preparations, comprising or consisting of (a) C-methyl flavonoids, a salt of C-methyl flavonoids and/or an extract containing C-methyl flavonoids, and (b) at least one inorganic salt or mineral substance.
C07J 17/00 - Normal steroids containing carbon, hydrogen, halogen, or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta[a]hydrophenanthrene skeleton
A23L 27/00 - SpicesFlavouring agents or condimentsArtificial sweetening agentsTable saltsDietetic salt substitutesPreparation or treatment thereof
A23G 3/36 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof characterised by the composition
A23G 4/06 - Chewing gum characterised by the composition
A23G 4/08 - Chewing gum characterised by the composition of the chewing gum base
Gynostemma pentaphyllumGynostemma pentaphyllum which are useful as a sweetener or sweet taste enhancer in preparations and compositions, especially oral edible compositions.
C07J 17/00 - Normal steroids containing carbon, hydrogen, halogen, or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta[a]hydrophenanthrene skeleton
B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (Germany)
Inventor
Siems, Kartsen
Riedel, Katja
Krohn, Michael
Abstract
The invention relates to a preparation containing (a) at least one NSAID active ingredient and (b) dehydroabietic acid or an extract containing dehydroabietic acid, as a drug.
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/167 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen atom of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
C07J 17/00 - Normal steroids containing carbon, hydrogen, halogen, or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta[a]hydrophenanthrene skeleton
A23L 27/00 - SpicesFlavouring agents or condimentsArtificial sweetening agentsTable saltsDietetic salt substitutesPreparation or treatment thereof
A23G 3/36 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof characterised by the composition
A23G 4/06 - Chewing gum characterised by the composition
A23G 4/08 - Chewing gum characterised by the composition of the chewing gum base
Suggested are compositions comprising natural stilbenes as a sweetener or sweetener enhancer in preparations and compositions, especially oral edible compositions comprising them.
Suggested are triterpene-glycoside compounds, which are obtainable by the extraction of Cylcocarya paliurus (Synonym: Pterocarya paliurus) and are useful as a sweetener or sweetener enhancer in preparations and compositions, especially oral edible compositions.
B.R.A.I.N. BIOTECHNOLOGY RESEARCH INFORMATION NETWORK AG (Germany)
Inventor
Siems, Karsten
Kluge, Grit
Krohn, Michael
Riedel, Katja
Abstract
The invention relates to preparations comprising or consisting of a) dehydroabietic acid, a dehydroabietic salt and/or a dehydroabietic acid-containing extract, and b1) at least one sweetener which is different from saccharose, and/or b2) at least one flavonoid, and/or b3) at least one inorganic salt or mineral used in food, and/or b4) at least one alkaloid present in food, and/or b5) at least one terpene present in food.
Suggested are triterpene-glycoside compounds, which are obtainable by the extraction of Momordica grosvenorii (Siraitia grosvenori) which are useful as a sweetener or sweetener enhancer in preparations and compositions, especially oral edible compositions.
C07J 17/00 - Normal steroids containing carbon, hydrogen, halogen, or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta[a]hydrophenanthrene skeleton
27.
NOVEL TRITERPENE-GLYCOSIDES AS SWEETENERS OR SWEETENER ENHANCERS
Suggested are triterpene-glycoside compounds, which are obtainable by the extraction of Momordica grosvenorii (Siraitia grosvenori) which are useful as a sweetener or sweetener enhancer in preparations and compositions, especially oral edible compositions.
C07H 15/24 - Condensed ring systems having three or more rings
C07J 17/00 - Normal steroids containing carbon, hydrogen, halogen, or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta[a]hydrophenanthrene skeleton
The present invention relates to an anti-dandruff composition comprising 1-acetoxychavicol acetate (I). Furthermore, the present invention relates to a method for preparing said anti-dandruff composition and the use of said anti-dandruff composition for treating or preventing Malassezia induced dandruff formation. Moreover, the present invention relates to a method for preparing an Alpinia galanga extract and an extract obtainable or obtained by said method as well as the use of this extract for treating Malassezia induced dandruff formation comprising applying an anti-dandruff composition comprising said extract.
A61K 8/97 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from algae, fungi, lichens or plantsCosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from derivatives thereof
The invention relates to cosmetic preparations, containing (a) at least one cosmetic formulation component from the group comprising oil bodies, emulsifiers, and surfactants and (b) at least one preservative from the group comprising glycolipids, which follows formula (I), in which n = 1 or n = 2, R1 means H or COCH3, R2 is the same or different and stands for H or a group (Ib), wherein n can represent the numbers 1, 2, or 3, R3 is the same or different and means H or OH, R4 means OH or OCH3, R5 means H or (II) or (III), wherein n can represent the numbers 1, 2, or 3, R6 means H or OH, and R7 means H or OH or =O, or one of the salts thereof.
A61K 8/92 - Oils, fats or waxesDerivatives thereof, e.g. hydrogenation products
A61K 8/99 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (USA)
ANALYTICON DISCOVERY GMBH (Germany)
Inventor
Djaballah, Hakim
Antczak, Christophe
Abramson, David, H.
Ambrosi, Horst-Dieter
Siems, Karsten
Genski, Thorsten
Abstract
In one aspect, the instant invention provides novel compounds and pharmaceutical compositions useful for treating proliferative diseases such as cancer. In another aspect, the invention provides methods of using certain compounds in the treatment of proliferative diseases such as cancer. In particular, the instant invention provides methods of treating ocular cancer (e.g., retinoblastoma) using intraarterial infusion to administer inventive compounds locally to the eye of a subject with an ocular cancer.
A01N 43/42 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
The invention relates to a pharmaceutical composition comprising a glucuronate, glucoside, and/or sulfo conjugate of 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one, or such a conjugate of a derivative of 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one, or a physiologically compatible salt of such a conjugate.
A61K 31/095 - Sulfur, selenium or tellurium compounds, e.g. thiols
A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
A61K 31/7012 - Compounds having a free or esterified carboxyl group attached, directly or through a carbon chain, to a carbon atom of the saccharide radical, e.g. glucuronic acid, neuraminic acid
patents
