Pike Therapeutics Inc.

Canada

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IPC Class
A61K 31/05 - Phenols 28
A61K 9/70 - Web, sheet or filament bases 27
A61K 9/00 - Medicinal preparations characterised by special physical form 26
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline 17
C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings 16
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1.

Transdermal Delivery of Tetrahydrocannabinol

      
Application Number 18773898
Status Pending
Filing Date 2024-07-16
First Publication Date 2025-01-09
Owner Pike Therapeutics Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

Provided is a transdermal drug delivery system comprising tetrahydrocannabinol (THC). Transdermal delivery can provide a drug plasma concentration at predetermined rate for a predetermined period of time with a simplified therapeutic regimen by decreasing dosing frequency for the treatment and/or prevention of pain and/or inflammation.

IPC Classes  ?

  • A61K 31/00 - Medicinal preparations containing organic active ingredients
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 47/02 - Inorganic compounds
  • A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
  • A61K 47/12 - Carboxylic acids; Salts or anhydrides thereof
  • A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers

2.

Transdermal Drug Delivery Systems for Administration of a Therapeutically Effective Amount of Apixaban and Other Direct Oral Anticoagulants

      
Application Number 18594497
Status Pending
Filing Date 2024-03-04
First Publication Date 2024-09-12
Owner Pike Therapeutics Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg
  • Plakogiannis, Rodoula
  • Lather, Tamanna

Abstract

Continuous drug delivery systems for apixaban and other direct oral anticoagulants (DOACs).

IPC Classes  ?

  • A61K 31/444 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases

3.

TRANSDERMAL DRUG DELIVERY SYSTEMS FOR ADMINISTRATION OF A THERAPEUTICALLY EFFECTIVE AMOUNT OF APIXABAN AND OTHER DIRECT ORAL ANTICOAGULANTS

      
Application Number IB2024052081
Publication Number 2024/184792
Status In Force
Filing Date 2024-03-04
Publication Date 2024-09-12
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg
  • Plakogiannis, Rodoula
  • Lather, Tamanna

Abstract

Method of preventing and treating thromboembolic conditions by using direct oral anticoagulants such as apixaban via transdermal, subcutaneous, intramuscular or buccal routes by avoiding the gastrointestinal tract.

IPC Classes  ?

  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/4545 - Non-condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
  • A61P 7/02 - Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
  • C07D 471/04 - Ortho-condensed systems

4.

Pharmaceutical Composition And Method For Treating Seizure Disorders

      
Application Number 18629364
Status Pending
Filing Date 2024-04-08
First Publication Date 2024-08-08
Owner Pike Therapeutics Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

The present disclosure relates to the transdermal administration of cannabidiol (CBD) for the reduction of seizure frequency in the treatment of “treatment-resistant epilepsy” (TRE).

IPC Classes  ?

  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/06 - Ointments; Bases therefor
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/165 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61K 31/36 - Compounds containing methylenedioxyphenyl groups, e.g. sesamin
  • A61K 31/4015 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/444 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
  • A61K 31/515 - Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

5.

Continuous Drug Delivery Systems and Methods

      
Application Number 18224183
Status Pending
Filing Date 2023-07-20
First Publication Date 2024-01-25
Owner Pike Therapeutics Inc. (Canada)
Inventor
  • Miles, Brad
  • Plakogiannis, Fotios M.

Abstract

Compositions and methods for the treatment and/or prevention and/or control of indications such as pain management, cancer, seizure disorders, and Parkinson's Disease using continuous drug delivery.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/00 - Medicinal preparations containing organic active ingredients
  • A61K 9/00 - Medicinal preparations characterised by special physical form

6.

CONTINUOUS DELIVERY SYSTEMS COMPRISING A CANNABINOID AND MEDICINAL USES THEREOF

      
Application Number IB2023057416
Publication Number 2024/018420
Status In Force
Filing Date 2023-07-20
Publication Date 2024-01-25
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Miles, Brad
  • Plakogiannis, Fotios

Abstract

Compositions comprising 0.1-50 % delta-9-tetrahydrocannabinol and/or cannabidiol in forms suitable for continuous delivery and use thereof in the treatment of a variety of diseases and pathological disorders are disclosed. In preferred embodiments, the compositions are in a form suitable for delivery via a portable infusion pump or transdermal patch. The disorders to be treated include pain, cancer, seizure disorders, and Parkinson's disease. Depending on the disorder to be treated, the compositions may optionally further comprise additional active agents such as dopaminergic agents.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

7.

TRANSDERMAL MICRO-DOSING DELIVERY OF PHARMACEUTICAL AGENTS

      
Application Number IB2022057210
Publication Number 2023/012691
Status In Force
Filing Date 2022-08-03
Publication Date 2023-02-09
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg

Abstract

The present disclosure relates to the transdermal administration of pharmaceutical agents, such as CBD, THC, psilocybin, psilocin, lysergic acid diethylamine (LSD), and/or ibogaine, and derivatives of these compounds, for the treatment and/or prevention and/or control of severe depression (treatment resistant), major depressive disorder, obsessive-compulsive disorder, quitting smoking, alcohol addiction, cocaine addiction, opioid addiction, anxiety (stress), adult ADHD, cluster headaches, and cancer related or other end-of-life psychological distress.

IPC Classes  ?

  • A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • A61K 31/48 - Ergoline derivatives, e.g. lysergic acid, ergotamine
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61P 25/00 - Drugs for disorders of the nervous system
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans
  • C07D 457/06 - Lysergic acid amides
  • C07D 487/04 - Ortho-condensed systems
  • C07F 9/572 - Five-membered rings

8.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF CHRONIC PAIN

      
Application Number 17725593
Status Pending
Filing Date 2022-04-21
First Publication Date 2022-11-03
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna

Abstract

The present disclosure relates to the to the transdermal administration of active agents, such as diclofenac and/or CBD and/or THC, and derivatives of these compounds, for the treatment and/or prevention and/or control of chronic pain.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 31/05 - Phenols
  • A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
  • A61K 9/00 - Medicinal preparations characterised by special physical form

9.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF CHRONIC PAIN

      
Document Number 03215685
Status Pending
Filing Date 2022-04-21
Open to Public Date 2022-10-27
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna

Abstract

The present disclosure relates to the to the transdermal administration of active agents, such as diclofenac and/or CBD and/or THC, and derivatives of these compounds, for the treatment and/or prevention and/or control of chronic pain.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07C 229/42 - Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

10.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF CHRONIC PAIN

      
Application Number IB2022053730
Publication Number 2022/224184
Status In Force
Filing Date 2022-04-21
Publication Date 2022-10-27
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna

Abstract

The present disclosure relates to the to the transdermal administration of active agents, such as diclofenac and/or CBD and/or THC, and derivatives of these compounds, for the treatment and/or prevention and/or control of chronic pain.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • A61K 31/196 - Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07C 229/42 - Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

11.

TRANSDERMAL DELIVERY OF CANNABIDIOL

      
Document Number 03214228
Status Pending
Filing Date 2022-04-07
Open to Public Date 2022-10-20
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

Provided is a transdermal drug delivery system comprising cannabidiol, or a cannabidiol salt alone or in combinations thereof. Transdermal delivery can provide a drug plasma concentration at predetermined rate for a predetermined period of time with a simplified therapeutic regimen by decreasing dosing frequency for the treatment and/or prevention of pain and/or inflammation.

IPC Classes  ?

12.

PHARMACEUTICAL COMPOSITION AND METHOD FOR TREATING SEIZURE DISORDERS

      
Document Number 03213953
Status Pending
Filing Date 2022-04-07
Open to Public Date 2022-10-13
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

The present disclosure relates to the transdermal administration of cannabidiol (CBD) for the reduction of seizure frequency in the treatment of "treatment-resistant epilepsy" (TRE).

IPC Classes  ?

  • A61K 31/05 - Phenols
  • A61P 25/08 - Antiepileptics; Anticonvulsants
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings

13.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS COMPRISING CBD OR THC FOR THE TREATMENT OF CANCER

      
Document Number 03200898
Status Pending
Filing Date 2021-12-02
Open to Public Date 2022-06-09
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

The present disclosure relates to methods of treating cancer and, more particularly, an active agent selected from the group consisting of tetrahydrocannabinol (THC), cannabidiol (CBD), or combinations thereof, in a dosage form for transdermal delivery in the treatment of cancer.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • A61P 35/00 - Antineoplastic agents
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

14.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF CANCER

      
Application Number 17540475
Status Pending
Filing Date 2021-12-02
First Publication Date 2022-06-09
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

The present disclosure relates to methods of treating cancer and, more particularly, an active agent selected from the group consisting of tetrahydrocannabinol (THC), cannabidiol (CBD), or combinations thereof, in a dosage form for transdermal delivery in the treatment of cancer.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form

15.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS COMPRISING CBD OR THC FOR THE TREATMENT OF CANCER

      
Application Number IB2021095002
Publication Number 2022/118303
Status In Force
Filing Date 2021-12-02
Publication Date 2022-06-09
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

The present disclosure relates to methods of treating cancer and, more particularly, an active agent selected from the group consisting of tetrahydrocannabinol (THC), cannabidiol (CBD), or combinations thereof, in a dosage form for transdermal delivery in the treatment of cancer.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • A61P 35/00 - Antineoplastic agents
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

16.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS OF CANNABINOIDS

      
Document Number 03187588
Status Pending
Filing Date 2021-08-13
Open to Public Date 2022-02-24
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg

Abstract

The present disclosure relates to the transdermal administration of nabilone and cannabinoids and derivatives of these compounds, for the treatment and/or prevention and/or control of medical conditions.

IPC Classes  ?

  • A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61P 1/08 - Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
  • A61P 25/00 - Drugs for disorders of the nervous system
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

17.

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE

      
Document Number 03187582
Status Pending
Filing Date 2021-08-13
Open to Public Date 2022-02-24
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg

Abstract

The current application relates to a topical pharmaceutical composition comprising at least one active agent selected from CBD and THC, solvent, surfactant, optional permeation enhancer, and optional adhesive/polymer. The topical composition is used for treating, preventing, or slowing the onset or progression of Parkinson's disease and/or related symptoms.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61P 25/16 - Anti-Parkinson drugs
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

18.

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE

      
Application Number IB2021057474
Publication Number 2022/038475
Status In Force
Filing Date 2021-08-13
Publication Date 2022-02-24
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg

Abstract

The current application relates to a topical pharmaceutical composition comprising at least one active agent selected from CBD and THC, solvent, surfactant, optional permeation enhancer, and optional adhesive/polymer. The topical composition is used for treating, preventing, or slowing the onset or progression of Parkinson's disease and/or related symptoms.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 31/05 - Phenols
  • A61K 9/70 - Web, sheet or filament bases
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61P 25/16 - Anti-Parkinson drugs
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

19.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS OF CANNABINOIDS

      
Application Number IB2021057483
Publication Number 2022/038479
Status In Force
Filing Date 2021-08-13
Publication Date 2022-02-24
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg

Abstract

The present disclosure relates to the transdermal administration of nabilone and cannabinoids and derivatives of these compounds, for the treatment and/or prevention and/or control of medical conditions.

IPC Classes  ?

  • A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61P 1/08 - Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
  • A61P 25/00 - Drugs for disorders of the nervous system
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

20.

PHARMACEUTICAL COMPOSITIONS AND METHODS FOR TREATING PARKINSON'S DISEASE

      
Application Number 17401374
Status Pending
Filing Date 2021-08-13
First Publication Date 2022-02-17
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg

Abstract

Pharmaceutical compositions and methods for treating and/or preventing and/or control of Parkinson's Disease and/or related symptoms in a patient.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 31/05 - Phenols
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
  • A61P 25/16 - Anti-Parkinson drugs
  • A61K 31/4985 - Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
  • A61K 31/4745 - Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenanthrolines
  • A61K 31/428 - Thiazoles condensed with carbocyclic rings
  • A61K 31/4045 - Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
  • A61K 31/473 - Quinolines; Isoquinolines ortho- or peri-condensed with carbocyclic ring systems, e.g. acridines, phenanthridines

21.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS OF NABILONE ALONE AND IN COMBINATION WITH CANNABINOIDS

      
Application Number 17401598
Status Pending
Filing Date 2021-08-13
First Publication Date 2022-02-17
Owner Pike Therapeutics, Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg

Abstract

The present disclosure relates to the to the transdermal administration of nabilone and cannabinoids and derivatives of these compounds, for the treatment and/or prevention and/or control of medical conditions.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form

22.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF MULTIPLE SCLEROSIS

      
Application Number IB2021055920
Publication Number 2022/003623
Status In Force
Filing Date 2021-07-01
Publication Date 2022-01-06
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna

Abstract

The present disclosure relates to the to the transdermal administration of THC and/or CBD and derivatives of these compounds, for the treatment and/or prevention and/or control of multiple sclerosis, multiple sclerosis-related muscle spasms, and pain and/or spasticity in multiple sclerosis.

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
  • A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

23.

TRANSDERMAL PHARMACEUTICAL FORMULATIONS FOR THE TREATMENT OF MULTIPLE SCLEROSIS

      
Application Number 17365060
Status Pending
Filing Date 2021-07-01
First Publication Date 2022-01-06
Owner Pike Therapeutics, Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna

Abstract

The present disclosure relates to the to the transdermal administration of THC and/or CBD and derivatives of these compounds, for the treatment and/or prevention and/or control of multiple sclerosis, multiple sclerosis-related muscle spasms, and pain and/or spasticity in multiple sclerosis.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/137 - Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine
  • A61K 31/277 - Nitriles; Isonitriles having a ring, e.g. verapamil
  • A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

24.

μ2-dose

      
Application Number 1628911
Status Registered
Filing Date 2021-10-13
Registration Date 2021-10-13
Owner Pike Therapeutics Inc. (Canada)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

Transdermal patches and pharmaceutical compositions for use in the treatment, prevention and control of depression, major depressive disorder, obsessive-compulsive disorder, smoking cessation, alcohol addiction, cocaine addiction, opioid addiction, anxiety (stress), adult adhd, cluster headaches, and cancer related and other end-of-life psychological distress.

25.

TRANSDERMAL AND/OR TOPICAL, PHARMACEUTICAL FORMULATIONS COMPRISING CANNABIDIOL AND/OR TETRAHYDROCANNABINOL FOR THE TREATMENT OF CHRONIC PAIN

      
Application Number 17235314
Status Pending
Filing Date 2021-04-20
First Publication Date 2021-11-11
Owner Pike Therapeutics, Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna

Abstract

The present disclosure relates to the to the transdermal administration of cannabinoids, such as, CBD and/or THC, and derivatives of these compounds, for the treatment and/or prevention and/or control of chronic pain.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/05 - Phenols
  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

26.

TRANSDERMAL AND/OR TOPICAL PHARMACEUTICAL FORMULATIONS COMPRISING CANNABIDIOL AND/OR TETRAHYDROCANNABINOL FOR THE TREATMENT OF CHRONIC PAIN

      
Document Number 03178878
Status Pending
Filing Date 2021-04-20
Open to Public Date 2021-10-28
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna

Abstract

The current application relates to a transdermal or topical pharmaceutical formulation comprising cannabidiol (CBD) and tetrahydrocannabinol (THC) for the treatment of chronical pain with reduced side effects in the patient. The transdermal or topical formulation can also be used for the treatment of various symptoms associated with multiple sclerosis (MS).

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 31/05 - Phenols
  • A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
  • A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

27.

TRANSDERMAL AND/OR TOPICAL PHARMACEUTICAL FORMULATIONS COMPRISING CANNABIDIOL AND/OR TETRAHYDROCANNABINOL FOR THE TREATMENT OF CHRONIC PAIN

      
Application Number IB2021000261
Publication Number 2021/214545
Status In Force
Filing Date 2021-04-20
Publication Date 2021-10-28
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios, M.
  • Lather, Tamanna

Abstract

The current application relates to a transdermal or topical pharmaceutical formulation comprising cannabidiol (CBD) and tetrahydrocannabinol (THC) for the treatment of chronical pain with reduced side effects in the patient. The transdermal or topical formulation can also be used for the treatment of various symptoms associated with multiple sclerosis (MS).

IPC Classes  ?

  • A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
  • A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings
  • C07D 311/80 - Dibenzopyrans; Hydrogenated dibenzopyrans

28.

TRANSDERMAL MICRO-DOSING DELIVERY OF PSYCHEDELICS DERIVATIVES

      
Document Number 03173048
Status Pending
Filing Date 2021-04-15
Open to Public Date 2021-10-21
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Modi, Nisarg

Abstract

The present disclosure relates to the transdermal administration of psychedelics, such as psilocybin, psilocin, lysergic acid diethyl amine (LSD), and/or ibogaine, and derivatives of these compounds, for the treatment and/or prevention and/or control of severe depression (treatment resistant), major depressive disorder, obsessive-compulsive disorder, quitting smoking, alcohol addiction, cocaine addiction, opioid addiction, anxiety (stress), adult ADHD, cluster headaches, and cancer related or other end-of-life psychological distress.

IPC Classes  ?

  • A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/4045 - Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
  • A61K 31/48 - Ergoline derivatives, e.g. lysergic acid, ergotamine
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • A61P 25/00 - Drugs for disorders of the nervous system
  • C07D 209/16 - Tryptamines
  • C07D 457/06 - Lysergic acid amides
  • C07D 487/04 - Ortho-condensed systems
  • C07F 9/572 - Five-membered rings

29.

TRANSDERMAL MICRO-DOSING DELIVERY OF PSYCHEDELICS DERIVATIVES

      
Application Number IB2021000248
Publication Number 2021/209815
Status In Force
Filing Date 2021-04-15
Publication Date 2021-10-21
Owner PIKE THERAPEUTICS, INC. (Canada)
Inventor
  • Plakogiannis, Fotios, M.
  • Modi, Nisarg

Abstract

The present disclosure relates to the transdermal administration of psychedelics, such as psilocybin, psilocin, lysergic acid diethyl amine (LSD), and/or ibogaine, and derivatives of these compounds, for the treatment and/or prevention and/or control of severe depression (treatment resistant), major depressive disorder, obsessive-compulsive disorder, quitting smoking, alcohol addiction, cocaine addiction, opioid addiction, anxiety (stress), adult ADHD, cluster headaches, and cancer related or other end-of-life psychological distress.

IPC Classes  ?

  • A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
  • A61K 31/4045 - Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
  • A61K 31/48 - Ergoline derivatives, e.g. lysergic acid, ergotamine
  • A61K 31/55 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61P 25/00 - Drugs for disorders of the nervous system
  • C07D 209/16 - Tryptamines
  • C07D 457/06 - Lysergic acid amides
  • C07D 487/04 - Ortho-condensed systems
  • C07F 9/572 - Five-membered rings

30.

Transdermal delivery of cannabidiol

      
Application Number 17227591
Grant Number 12121617
Status In Force
Filing Date 2021-04-12
First Publication Date 2021-08-26
Grant Date 2024-10-22
Owner Pike Therapeutics Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

Provided is a transdermal drug delivery system comprising cannabidiol, or a cannabidiol salt alone or in combinations thereof. Transdermal delivery can provide a drug plasma concentration at predetermined rate for a predetermined period of time with a simplified therapeutic regimen by decreasing dosing frequency for the treatment and/or prevention of pain and/or inflammation.

IPC Classes  ?

  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/05 - Phenols
  • A61K 47/06 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite

31.

Pharmaceutical composition and method for treating seizure disorders

      
Application Number 17225654
Grant Number 12016829
Status In Force
Filing Date 2021-04-08
First Publication Date 2021-08-19
Grant Date 2024-06-25
Owner Pike Therapeutics Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

The present disclosure relates to the transdermal administration of cannabidiol (CBD) for the reduction of seizure frequency in the treatment of “treatment-resistant epilepsy” (TRE).

IPC Classes  ?

  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/06 - Ointments; Bases therefor
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 31/165 - Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
  • A61K 31/19 - Carboxylic acids, e.g. valproic acid
  • A61K 31/36 - Compounds containing methylenedioxyphenyl groups, e.g. sesamin
  • A61K 31/4015 - Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
  • A61K 31/423 - Oxazoles condensed with carbocyclic rings
  • A61K 31/444 - Non-condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. amrinone
  • A61K 31/515 - Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
  • A61K 31/5513 - 1,4-Benzodiazepines, e.g. diazepam
  • A61K 31/675 - Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate

32.

M2-DOSE

      
Application Number 210384700
Status Registered
Filing Date 2021-04-30
Registration Date 2024-08-23
Owner Pike Therapeutics Inc. (Canada)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Transdermal patches and pharmaceutical compositions for use in the treatment, prevention and control of depression, major depressive disorder, obsessive-compulsive disorder, smoking cessation, alcohol addiction, cocaine addiction, opioid addiction, anxiety (stress), adult ADHD, cluster headaches, and cancer related and other end-of-life psychological distress

33.

MICRO-MICRODOSE

      
Application Number 210384800
Status Registered
Filing Date 2021-04-30
Registration Date 2024-08-23
Owner Pike Therapeutics Inc. (Canada)
NICE Classes  ? 05 - Pharmaceutical, veterinary and sanitary products

Goods & Services

(1) Transdermal patches and pharmaceutical compositions for use in the treatment, prevention and control of depression, major depressive disorder, obsessive-compulsive disorder, smoking cessation, alcohol addiction, cocaine addiction, opioid addiction, anxiety (stress), adult ADHD, cluster headaches, and cancer related and other end-of-life psychological distress

34.

TRANSDERMAL DELIVERY OF CANNABIDIOL

      
Document Number 03155181
Status Pending
Filing Date 2020-10-13
Open to Public Date 2021-04-22
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

Provided is a transdermal drug delivery system comprising cannabidiol, or its salt alone or in combinations thereof. Transdermal delivery can provide a drug plasma concentration at predetermined rate for a predetermined period of time with a simplified therapeutic regimen by decreasing dosing frequency for the treatment and/or prevention of pain and/or inflammation.

IPC Classes  ?

  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings

35.

Pharmaceutical composition and method for treating seizure disorders

      
Application Number 17065851
Grant Number 12186280
Status In Force
Filing Date 2020-10-08
First Publication Date 2021-04-22
Grant Date 2025-01-07
Owner Pike Therapeutics Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

The present disclosure relates to the transdermal administration of cannabidiol (CBD) for the reduction of seizure frequency in the treatment of “treatment-resistant epilepsy” (TRE).

IPC Classes  ?

36.

TRANSDERMAL COMPOSITIONS COMPRISING CANNABIDIOL (CBD) FOR USE IN THE TREATMENT OF SEIZURE DISORDERS

      
Document Number 03155176
Status Pending
Filing Date 2020-10-08
Open to Public Date 2021-04-15
Owner PIKE THERAPEUTICS INC. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

The preparation of transdermal pharmaceutical compositions comprising cannabidiol (CBD) and use thereof in the treatment of seizure disorders is disclosed. Preferably, the CBD is provided in the form of a highly purified extract of cannabis that comprises at least 90 % (w/w) of cannabidiol. The transdermal compositions may take a number of different forms and incorporate various different excipients (such as propylene glycol and hexylene glycol). The seizure disorders treated include various types of treatment resistant epilepsy (TRE).

IPC Classes  ?

  • A61K 31/05 - Phenols
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61K 9/70 - Web, sheet or filament bases
  • A61K 36/185 - Magnoliopsida (dicotyledons)
  • A61M 37/00 - Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61P 25/08 - Antiepileptics; Anticonvulsants
  • C07C 39/23 - Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing six-membered aromatic rings and other rings, with unsaturation outside the aromatic rings

37.

Transdermal delivery of cannabidiol

      
Application Number 17069181
Grant Number 12097293
Status In Force
Filing Date 2020-10-13
First Publication Date 2021-04-15
Grant Date 2024-09-24
Owner Pike Therapeutics Inc. (Canada)
Inventor
  • Plakogiannis, Fotios M.
  • Lather, Tamanna
  • Modi, Nisarg
  • Borovinskaya, Marina

Abstract

Provided is a transdermal drug delivery system comprising cannabidiol, or a cannabidiol salt alone or in combinations thereof. Transdermal delivery can provide a drug plasma concentration at predetermined rate for a predetermined period of time with a simplified therapeutic regimen by decreasing dosing frequency for the treatment and/or prevention of pain and/or inflammation.

IPC Classes  ?