Evaxion Biotech A/S

Denmark

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IPC Class
A61K 39/00 - Medicinal preparations containing antigens or antibodies 23
A61K 39/085 - Staphylococcus 12
A61P 31/04 - Antibacterial agents 12
C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G) 12
C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria 11
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05 - Pharmaceutical, veterinary and sanitary products 2
09 - Scientific and electric apparatus and instruments 2
42 - Scientific, technological and industrial services, research and design 2
Status
Pending 22
Registered / In Force 22

1.

Vaccines targeting Neisseria gonorrhoeae

      
Application Number 18576831
Status Pending
Filing Date 2022-07-05
First Publication Date 2024-12-26
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Mattsson, Andreas Holm
  • Steenmans, Christian Skjødt

Abstract

Proteins, protein fragments, nucleic acids and vectors derived from Neisseria gonorrhoeae, as well as to methods of inducing immunity against N. gonorrhoeae. Also disclosed are antibodies binding to the proteins and protein fragments.

IPC Classes  ?

  • A61K 39/095 - Neisseria
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61P 31/04 - Antibacterial agents
  • C07K 14/22 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Neisseriaceae (F), e.g. Acinetobacter
  • C12N 15/74 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora

2.

Proteins and nucleic acids useful in vaccines targeting Pseudomonas aeruginosa

      
Application Number 18732821
Status Pending
Filing Date 2024-06-04
First Publication Date 2024-09-26
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

Disclosed are immunogenic proteins from Pseudomonas aeruginosa as well as nucleic acids, vectors and transformd cells useful for expression of the proteins. Also disclosed are methods for prophylaxis of infection with Pseudomonas aeruginosa using the proteins, nucleic acids, vectors or transformed cells.

IPC Classes  ?

  • C07K 14/21 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pseudomonadaceae (F)
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/104 - Pseudomonas
  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
  • A61P 31/04 - Antibacterial agents
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria

3.

PROTEINS AND NUCLEIC ACIDS USEFUL IN VACCINES TARGETING STAPHYLOCOCCUS AUREUS

      
Application Number 18479501
Status Pending
Filing Date 2023-10-02
First Publication Date 2024-07-11
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattson, Andreas Holm

Abstract

The present invention relates to proteins and nucleic acids derived from Staphylococcus aureus as well as therapeutic and diagnostic uses of the proteins and nucleic acids.

IPC Classes  ?

  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • A61K 39/085 - Staphylococcus
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

4.

PEPTIDES DERIVED FROM ACINETOBACTER BAUMANNII AND THEIR USE IN VACCINATION

      
Application Number 18525109
Status Pending
Filing Date 2023-11-30
First Publication Date 2024-07-11
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattson, Andreas Holm

Abstract

The present invention relates to proteins derived from Acinetobacter baumanii, nucleic acids encoding the proteins, antibodies specific for the proteins as well as methods of therapy, prophylaxis, and diagnosis that utilise the proteins, nucleic acids, and antibodies.

IPC Classes  ?

  • A61K 39/104 - Pseudomonas
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • C07K 14/21 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pseudomonadaceae (F)

5.

PROCESS FOR PRODUCTION OF SYNTHETIC CIRCULAR DNA

      
Application Number EP2023083759
Publication Number 2024/115669
Status In Force
Filing Date 2023-11-30
Publication Date 2024-06-06
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Grønlund, Jesper Tranholm
  • Sørensen, Anders Bundgård
  • Kringelum, Jens Vindahl

Abstract

The disclosure provides a novel process for producing a synthetic circular DNA (scDNA) molecule and a novel scDNA molecule which can be produced by the method. The disclosure further provides therapeutical methods using the scDNA molecule.

IPC Classes  ?

  • C12Q 1/6844 - Nucleic acid amplification reactions
  • C12N 15/64 - General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host

6.

Vaccines targeting Pseudomonas aeruginosa

      
Application Number 18340479
Status Pending
Filing Date 2023-06-23
First Publication Date 2024-03-07
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

Immunogenic proteins from Pseudomonas aeruginosa as well as nucleic acids, vectors and transformed cells useful for expression of the proteins. Also disclosed are methods for prophylaxis of infection with Pseudomonas aeruginosa using the proteins, nucleic acids, vectors or transformed cel

IPC Classes  ?

  • C07K 14/21 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pseudomonadaceae (F)
  • A61K 39/104 - Pseudomonas
  • A61P 31/04 - Antibacterial agents
  • C07K 14/33 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Clostridium (G)
  • C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
  • C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses

7.

APC targeting units for immunotherapy

      
Application Number 18004889
Status Pending
Filing Date 2021-07-14
First Publication Date 2023-11-09
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Rønø, Birgitte
  • Calvo, Marina Barrio
  • Sørensen, Anders Bundgård
  • Thygesen, Christian
  • Kringelum, Jens
  • Friis, Stine

Abstract

Immune therapy and vaccines, such as cancer immunotherapy, or vaccines for infections with microorganisms, such as a bacterial or viral infection. In particular, the present invention relates to methods and products for prophylactic or treating cancer or infections with microorganisms by administration of specific fusion polypeptides or nucleic acids encoding such fusion polypeptides.

IPC Classes  ?

  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/215 - Coronaviridae, e.g. avian infectious bronchitis virus
  • A61P 37/04 - Immunostimulants

8.

STAPHYLOCOCCAL PROTEIN VARIANTS AND TRUNCATES

      
Application Number EP2022062056
Publication Number 2023/213393
Status In Force
Filing Date 2022-05-04
Publication Date 2023-11-09
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Mattsson, Andreas Holm
  • Kringelum, Jens Vindahl
  • Comstedt, Pär
  • Thygesen, Christian

Abstract

The present application discloses novel polypeptides, polynucleotides, expression vectors and novel immunogenic compositions derived from Staphylococcus aureus, in particular novel polypeptides, polynucleotides, expression vectors and compositions derived from/related to the SpA, Hla, Aur and LukE polypeptides. Also disclosed is methods of immunity induction utilising the polypeptides, polynucleotides, expression vectors, and immunogenic compositions.

IPC Classes  ?

  • A61K 39/085 - Staphylococcus
  • A61P 31/04 - Antibacterial agents
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)

9.

Process for preparation of neopepitope-containing vaccine agents

      
Application Number 18007061
Status Pending
Filing Date 2021-07-30
First Publication Date 2023-08-17
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Trolle, Thomas
  • Garde, Christian
  • Klausen, Michael Schantz
  • Kringelum, Jens

Abstract

The present invention presents an improved method for identification of neoepitopes useful in active immunotherapy targeting malignant neoplasms. The method integrates identification of somatic variants of expression product with a balanced evaluation of such variants' 1) ability to bind MHC, 2) ability to induce immune responses, 3) clonal coverage in the tumour tissue, and 4) ability to evade immune responses. Also, the method is complemented by a method for purposive deselection of neoepitopes that could induced undesired immune response against normal cells. Also disclosed is a method for preparing immunogenic compositions, a method for treatment of cancer, and a computer system for identifying neoepitopes and neopeptides

IPC Classes  ?

  • G16B 20/20 - Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
  • G16B 20/50 - Mutagenesis
  • G06N 20/00 - Machine learning
  • G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment

10.

PERSONALIZED CANCER THERAPY TARGETING NORMALLY NON-EXPRESSED SEQUENCES

      
Document Number 03241220
Status Pending
Filing Date 2022-12-16
Open to Public Date 2023-06-22
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Garde, Christian
  • Trolle, Thomas
  • Kringelum, Jens Vindahl
  • Garces, Pablo
  • Jappe, Emma Christine

Abstract

Provided is a method for identifying immunogenic amino acid sequences in a sample of malignant tissue from a patient comprising A) determining amino acid sequences of proteinaceous expression products from the malignant tissue,B) analysing said amino acid sequences to identify therein proteinaceous expression products of selected genomic sequences in the patient's species, C) identifying - in the proteinaceous expression products ? the amino acid sequences, which are those that will bind to MHC molecules of the patient,where said selected genomic sequences constitute a subset of all sequences of the genome of said species and where said subset is constituted by sequences, which encode proteinaceous expression products in at most 5% of samples from any healthy tissue, where said healthy tissue is a tissue of a type found in the patient, and where said healthy tissue optionally does not include testis tissue and/or brain tissue. Also, a related method for treatment of cancer is provided as well as a computer system.In addition is provided a method for stratifying cancer patients into groups of those eligible for immunotherapy or not, based on their burden of expression of endogenous retrovirus.

IPC Classes  ?

  • G16B 25/10 - Gene or protein expression profilingExpression-ratio estimation or normalisation
  • G16B 20/30 - Detection of binding sites or motifs

11.

PERSONALIZED CANCER THERAPY TARGETING NORMALLY NON-EXPRESSED SEQUENCES

      
Application Number EP2022086444
Publication Number 2023/111306
Status In Force
Filing Date 2022-12-16
Publication Date 2023-06-22
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Garde, Christian
  • Trolle, Thomas
  • Kringelum, Jens Vindahl
  • Garces, Pablo
  • Jappe, Emma Christine

Abstract

Provided is a method for identifying immunogenic amino acid sequences in a sample of malignant tissue from a patient comprising A) determining amino acid sequences of proteinaceous expression products from the malignant tissue,B) analysing said amino acid sequences to identify therein proteinaceous expression products of selected genomic sequences in the patient's species, C) identifying - in the proteinaceous expression products – the amino acid sequences, which are those that will bind to MHC molecules of the patient,where said selected genomic sequences constitute a subset of all sequences of the genome of said species and where said subset is constituted by sequences, which encode proteinaceous expression products in at most 5% of samples from any healthy tissue, where said healthy tissue is a tissue of a type found in the patient, and where said healthy tissue optionally does not include testis tissue and/or brain tissue. Also, a related method for treatment of cancer is provided as well as a computer system.In addition is provided a method for stratifying cancer patients into groups of those eligible for immunotherapy or not, based on their burden of expression of endogenous retrovirus.

IPC Classes  ?

  • G16B 25/10 - Gene or protein expression profilingExpression-ratio estimation or normalisation
  • G16B 20/30 - Detection of binding sites or motifs

12.

Neoepitope immunotherapy with APC targeting unit

      
Application Number 17995601
Status Pending
Filing Date 2021-04-07
First Publication Date 2023-05-11
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Rønø, Birgitte
  • Calvo, Marina Barrio
  • Sørensen, Anders Bundgård
  • Thygesen, Christian
  • Kringelum, Jens
  • Friis, Stine

Abstract

The present invention relates to cancer therapy, in particular cancer immunotherapy. In particular, the present invention relates to methods and products for treating cancer by administration of specific fusion polypeptides or nucleic acids encoding such fusion polypeptides.

IPC Classes  ?

  • C07K 14/74 - Major histocompatibility complex [MHC]
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • C12N 15/62 - DNA sequences coding for fusion proteins
  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
  • A61P 35/00 - Antineoplastic agents
  • C07K 14/52 - CytokinesLymphokinesInterferons
  • C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
  • C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals

13.

Vaccines targeting Neisseria gonorrhoeae

      
Application Number 17791038
Status Pending
Filing Date 2021-01-06
First Publication Date 2023-02-16
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Mattsson, Andreas Holm
  • Steenmans, Christian Skjødt

Abstract

Proteins, protein fragments, nucleic acids and vectors derived from Neisseria gonorrhoeae, as well as to methods of inducing immunity against N. gonorrhoeae. Also disclosed are antibodies binding to the proteins and protein fragments.

IPC Classes  ?

14.

Chimeric proteins for inducing immunity towards infection with S. aureus

      
Application Number 17816145
Status Pending
Filing Date 2022-07-29
First Publication Date 2023-02-09
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm
  • Kringelum, Jens

Abstract

Disclosed is chimeric polypeptides derived from S. aureus proteins having SEQ ID NOs: 1-9 and 139-146. The chimeric polypeptides are useful as immunogens for providing protective immunity against S. aureus infection. Also disclosed are compositions, methods of treatment and prophylaxis, nucleic acids and vectors comprising the nucleic acids.

IPC Classes  ?

  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • A61K 39/085 - Staphylococcus
  • A61P 31/04 - Antibacterial agents

15.

VACCINES TARGETING NEISSERIA GONORRHOEAE

      
Document Number 03224564
Status Pending
Filing Date 2022-07-05
Open to Public Date 2023-01-12
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Mattsson, Andreas Holm
  • Steenmans, Christian Skjodt

Abstract

The present invention relates to proteins, protein fragments, nucleic acids and vectors derived from Neisseria gonorrhoeae, as well as to methods of inducing immunity against N. gonorrhoeae. Also disclosed are antibodies binding to the proteins and protein fragments.

IPC Classes  ?

  • C07K 14/22 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Neisseriaceae (F), e.g. Acinetobacter
  • A61K 39/095 - Neisseria
  • A61P 31/04 - Antibacterial agents
  • C07K 19/00 - Hybrid peptides
  • C12N 1/21 - BacteriaCulture media therefor modified by introduction of foreign genetic material
  • C12N 15/31 - Genes encoding microbial proteins, e.g. enterotoxins
  • C12N 15/62 - DNA sequences coding for fusion proteins
  • C12N 15/63 - Introduction of foreign genetic material using vectorsVectorsUse of hosts thereforRegulation of expression

16.

VACCINES TARGETING NEISSERIA GONORRHOEAE

      
Application Number EP2022068509
Publication Number 2023/280807
Status In Force
Filing Date 2022-07-05
Publication Date 2023-01-12
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Mattsson, Andreas Holm
  • Steenmans, Christian Skjødt

Abstract

The present invention relates to proteins, protein fragments, nucleic acids and vectors derived from Neisseria gonorrhoeae, as well as to methods of inducing immunity against N. gonorrhoeae. Also disclosed are antibodies binding to the proteins and protein fragments.

IPC Classes  ?

  • A61K 39/095 - Neisseria
  • A61P 31/04 - Antibacterial agents
  • C07K 14/22 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Neisseriaceae (F), e.g. Acinetobacter

17.

METHOD FOR PREDICTING RESPONSE TO CANCER IMMUNOTHERAPY

      
Application Number EP2022068877
Publication Number 2023/280973
Status In Force
Filing Date 2022-07-07
Publication Date 2023-01-12
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Mattsson, Andreas Holm
  • Garde, Christian

Abstract

The present invention relates to method for predicting patient responses to cancer immunotherapy, in particular treatment with immune checkpoint inhibitors and/or treatment involving induction of specific antitumour immunity. The method comprises quantitively determining the expression levels of MHC Class I and II molecule isotypes by the cells of the microenvironment of the patient's malignant neoplasm and calculating a combined expression score value from weighted expression levels of at least HLA-A, -B, -C, -DR isotypes. Also provided are methods of treatment and determination of eligibility for treatment.

IPC Classes  ?

  • C12Q 1/6886 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer

18.

VACCINATION TARGETING INTRACELLULAR PATHOGENS

      
Application Number EP2022064157
Publication Number 2022/248531
Status In Force
Filing Date 2022-05-25
Publication Date 2022-12-01
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Sørensen, Anders Bundgaard
  • Vindahl Kringelum, Jens
  • Garde, Christian
  • Trolle, Thomas
  • Klausen, Michael Schantz
  • Thygesen, Christian
  • Persson, Gry
  • Grønlund, Jesper Tranholm

Abstract

Provided are novel fusion polypeptides comprising a B-cell epitope-rich region, which comprises at least one fragment of at least one surface exposed protein from an intracellular pathogen, and a T-cell epitope-rich region, which comprises at least 2 densely arranged groups of T-cell epitope hotspots comprising at least one CTL inducing amino acid sequence, where the epitope hotspots are derived from at least two non-identical proteins of said intracellular pathogen. Also disclosed are nucleic acids and vectors encoding the fusion polypeptides and pharmaceutical means and methods based on the fusion polypeptides, nucleic acids and vectors.

IPC Classes  ?

  • C07K 14/195 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria
  • A61K 39/02 - Bacterial antigens
  • A61K 39/12 - Viral antigens
  • C07K 14/005 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from viruses
  • C07K 14/52 - CytokinesLymphokinesInterferons
  • C07K 14/705 - ReceptorsCell surface antigensCell surface determinants

19.

Method for identifying T-cell epitopes

      
Application Number 17642335
Status Pending
Filing Date 2020-09-11
First Publication Date 2022-10-20
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Kringelum, Jens
  • Jappe, Emma
  • Garde, Christian
  • Purcell, Anthony
  • Ramarathinam, Sri
  • Croft, Nathan

Abstract

A method for T-cell epitope prediction where quantitative scores of stability in the binding between peptides and MHC molecules are integrated into the derivation of the likelihood that a peptide of defined amino acid sequence constitutes a T-cell epitope. Preferably, stability data are obtained an MS-based method for identification of MHC binding peptides, where the binding capability is quantitatively assessed to allow distinction between stably binding peptides and peptides that are unlikely to be presented to T-cells. The method includes a step of time-course or thermostability testing of naturally processed peptides bound to MHC. Also disclosed are methods for preparation of personalized immunogenic compositions, methods of therapeutic treatment of malignancies, and a computer system that implements the T-cell epitope prediction method.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
  • G16B 40/10 - Signal processing, e.g. from mass spectrometry [MS] or from PCR
  • G16B 15/30 - Drug targeting using structural dataDocking or binding prediction

20.

EVAXION

      
Application Number 1666549
Status Registered
Filing Date 2022-02-10
Registration Date 2022-02-10
Owner EVAXION BIOTECH A/S (Denmark)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Pharmaceuticals and medical preparations; medicine for treatment of cancer; pharmaceuticals preparations and substances for the treatment of cancer, viral diseases, allergy, autoimmune diseases, microbiota dysbiosis and parasites; biopharmaceuticals for the treatment of cancer, viral diseases, allergy, autoimmune diseases, microbiota dysbiosis and parasites; preparations for immunotherapy; antibodies; vaccines for human use; viral vaccines; vaccine adjuvants; cells for medical use. Software; software based on artificial intelligence; artificial intelligence and machine learning software; platforms for artificial intelligence; software for the treatment of cancer; software for design and development of immunotherapy; software and software based on artificial intelligence for identification of antigens and epitopes; software and software based on artificial intelligence for design and development of vaccines and medicines; software and software based on artificial intelligence for the treatment of cancer, viral diseases, allergy, autoimmune diseases, microbiota dysbiosis and parasites. Scientific and technological research and services; research and development services in the field of immunology and oncology, decoding of data; research and development of pharmaceuticals; medical and pharmacological research services; basic and clinical research in the field of science and medicine; research and development of vaccines and medicines; scientific and technological research relating to virus, oncology, and autoimmune diseases, scientific and technological research relating to allergies; blood processing, namely the blood process of patients' blood to isolate lymphocytes for the use in immunotherapy for therapeutic medical research.

21.

Nucleic acid vaccination using neo-epitope encoding constructs

      
Application Number 17437940
Status Pending
Filing Date 2020-03-11
First Publication Date 2022-06-16
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Rønø, Birgitte
  • Kringelum, Jens
  • Sørensen, Anders Bundgård
  • Trolle, Thomas

Abstract

Compositions and methods for DNA vaccination that target cancer. The method for anti-cancer vaccination using a plasmid based vaccine comprises regions encoding neo-epitopes and comprising amphiphilic block copolymers such as poloxamer and poloxamine agents.

IPC Classes  ?

  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

22.

Vaccines targeting H. influenzae

      
Application Number 17433945
Status Pending
Filing Date 2020-02-27
First Publication Date 2022-05-12
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Mattsson, Andreas Holm
  • Hansen, Christian Skjødt

Abstract

Immunogenic proteins from nontypable Haemophilus influenzae as well as nucleic acids, vectors and transformed cells useful for expression of the proteins. Methods for prophylaxis of infection with nontypable Haemophilus influenzae using the proteins, nucleic acids, vectors or transformed cells.

IPC Classes  ?

  • A61K 39/102 - PasteurellaHaemophilus
  • C07K 14/285 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

23.

Pseudomonas aeruginosa

      
Application Number 17532034
Grant Number 12006342
Status In Force
Filing Date 2021-11-22
First Publication Date 2022-03-10
Grant Date 2024-06-11
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

Pseudomonas aeruginosa using the proteins, nucleic acids, vectors or transformed cells.

IPC Classes  ?

  • C07K 14/21 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pseudomonadaceae (F)
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/104 - Pseudomonas
  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
  • A61P 31/04 - Antibacterial agents
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria

24.

EVAXION

      
Serial Number 79342587
Status Registered
Filing Date 2022-02-10
Registration Date 2023-08-29
Owner EVAXION BIOTECH A/S (Denmark)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Pharmaceuticals and medical preparations for treating cancer and infectious diseases; medicine for treatment of cancer; pharmaceuticals preparations and substances for the treatment of cancer, viral diseases, allergy, autoimmune diseases, microbiota dysbiosis, and parasites; biopharmaceuticals for the treatment of cancer, viral diseases, allergy, autoimmune diseases, microbiota dysbiosis, and parasites; immunotherapy preparations for treating cancer and infectious diseases; monoclonal antibodies (mAb) for medical purposes; vaccines for human use; viral vaccines; vaccine adjuvants; cells for medical use Downloadable software for design of pharmaceuticals; downloadable artificial intelligence software for design of pharmaceuticals; downloadable artificial intelligence and machine learning software for design of pharmaceuticals; downloadable artificial intelligence software platforms for design of pharmaceuticals; downloadable software for evaluating medical treatment options and treatment outcomes for cancer; downloadable software for design and development of immunotherapy; downloadable software and downloadable artificial intelligence software for identifying antigens and epitopes; downloadable software and downloadable artificial intelligence software for designing and developing vaccines and medicines; downloadable software and downloadable artificial intelligence software for designing pharmaceuticals for cancer, viral diseases, allergy, autoimmune diseases, microbiota dysbiosis and parasites Scientific and technological research services in the field of oncology, infectious diseases, and immunology; scientific research and development services in the fields of immunology and oncology; decoding of data; research and development of pharmaceuticals; medical and pharmacological research services; clinical medical research in the field of oncology, infectious diseases, and immunology; research and development of vaccines and medicines; scientific and technological research relating to virus, oncology, and autoimmune diseases; scientific and technological research relating to allergies

25.

PROCESS FOR PREPARATION OF NEOPEPITOPE-CONTAINING VACCINE AGENTS

      
Application Number EP2021071380
Publication Number 2022/023521
Status In Force
Filing Date 2021-07-30
Publication Date 2022-02-03
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Trolle, Thomas
  • Garde, Christian
  • Klausen, Michael, Schrantz
  • Kringelum, Jens

Abstract

The present invention presents an improved method for identification of neoepitopes useful in active immunotherapy targeting malignant neoplasms. The method integrates identification of somatic variants of expression product with a balanced evaluation of such variants' 1) ability to bind MHC, 2) ability to induce immune responses, 3) clonal coverage in the tumour tissue, and 4) ability to evade immune responses. Also, the method is complemented by a method for purposive deselection of neoepitopes that could induced undesired immune response against normal cells. Also disclosed is a method for preparing immunogenic compositions, a method for treatment of cancer, and a computer system for identifying neoepitopes and neopeptides.

IPC Classes  ?

  • G16B 20/20 - Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
  • G16B 20/50 - Mutagenesis
  • G16B 40/20 - Supervised data analysis

26.

PROCESS FOR PREPARATION OF NEOPEPITOPE-CONTAINING VACCINE AGENTS

      
Document Number 03187546
Status Pending
Filing Date 2021-07-30
Open to Public Date 2022-02-03
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Trolle, Thomas
  • Garde, Christian
  • Klausen, Michael Schrantz
  • Kringelum, Jens

Abstract

The present invention presents an improved method for identification of neoepitopes useful in active immunotherapy targeting malignant neoplasms. The method integrates identification of somatic variants of expression product with a balanced evaluation of such variants' 1) ability to bind MHC, 2) ability to induce immune responses, 3) clonal coverage in the tumour tissue, and 4) ability to evade immune responses. Also, the method is complemented by a method for purposive deselection of neoepitopes that could induced undesired immune response against normal cells. Also disclosed is a method for preparing immunogenic compositions, a method for treatment of cancer, and a computer system for identifying neoepitopes and neopeptides.

IPC Classes  ?

  • G16B 20/20 - Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
  • G16B 20/50 - Mutagenesis
  • G16B 40/20 - Supervised data analysis

27.

APC TARGETING UNITS FOR IMMUNOTHERAPY

      
Document Number 03183951
Status Pending
Filing Date 2021-07-14
Open to Public Date 2022-01-20
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Rono, Birgitte
  • Calvo, Marina Barrio
  • Sorensen, Anders Bundgaard
  • Thygesen, Christian
  • Kringelum, Jens
  • Friis, Stine

Abstract

The present invention relates to immune therapy and vaccines, such as cancer immunotherapy, or vaccines for infections with microorganisms, such as a bacterial or viral infection. In particular, the present invention relates to methods and products for prophylactic or treating cancer or infections with microorganisms by administration of specific fusion polypeptides or nucleic acids encoding such fusion polypeptides.

IPC Classes  ?

28.

APC TARGETING UNITS FOR IMMUNOTHERAPY

      
Application Number EP2021069582
Publication Number 2022/013277
Status In Force
Filing Date 2021-07-14
Publication Date 2022-01-20
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Rønø, Birgitte
  • Calvo, Marina, Barrio
  • Sørensen, Anders, Bundgaard
  • Thygesen, Christian
  • Kringelum, Jens
  • Friis, Stine

Abstract

The present invention relates to immune therapy and vaccines, such as cancer immunotherapy, or vaccines for infections with microorganisms, such as a bacterial or viral infection. In particular, the present invention relates to methods and products for prophylactic or treating cancer or infections with microorganisms by administration of specific fusion polypeptides or nucleic acids encoding such fusion polypeptides.

IPC Classes  ?

29.

Proteins and nucleic acids useful in vaccines targeting Staphylococcus aureus

      
Application Number 17351032
Status Pending
Filing Date 2021-06-17
First Publication Date 2021-12-16
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

Disclosed are novel immunogenic proteins derived from Staphylococcus aureus, as well as methods for their use in conferring protective immunity against S. aureus infections. Also disclosed are nucleic acids encoding the proteins and methods of use of these nucleic acids.

IPC Classes  ?

  • A61K 39/085 - Staphylococcus
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)

30.

NEOEPITOPE IMMUNOTHERAPY WITH APC TARGETING UNIT

      
Document Number 03174417
Status Pending
Filing Date 2021-04-07
Open to Public Date 2021-10-14
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Rono, Birgitte
  • Calvo, Marina Barrio
  • Sorensen, Anders Bundgard
  • Thygesen, Christian
  • Kringelum, Jens
  • Friis, Stine

Abstract

The present invention relates to cancer therapy, in particular cancer immunotherapy. In particular, the present invention relates to methods and products for treating cancer by administration of specific fusion polypeptides or nucleic acids encoding such fusion polypeptides.

IPC Classes  ?

  • A61K 39/385 - Haptens or antigens, bound to carriers
  • C12N 15/117 - Nucleic acids having immunomodulatory properties, e.g. containing CpG-motifs
  • A61K 47/64 - Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
  • A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
  • A61P 35/00 - Antineoplastic agents
  • C07K 14/52 - CytokinesLymphokinesInterferons
  • C07K 19/00 - Hybrid peptides
  • C12N 15/19 - InterferonsLymphokinesCytokines
  • C12N 15/62 - DNA sequences coding for fusion proteins
  • C12N 15/85 - Vectors or expression systems specially adapted for eukaryotic hosts for animal cells

31.

NEOEPITOPE IMMUNOTHERAPY WITH APC TARGETING UNIT

      
Application Number EP2021059117
Publication Number 2021/204911
Status In Force
Filing Date 2021-04-07
Publication Date 2021-10-14
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Rønø, Birgitte
  • Calvo, Marina, Barrio
  • Sørensen, Anders, Bundgård
  • Thygesen, Christian
  • Kringelum, Jens
  • Friis, Stine

Abstract

The present invention relates to cancer therapy, in particular cancer immunotherapy. In particular, the present invention relates to methods and products for treating cancer by administration of specific fusion polypeptides or nucleic acids encoding such fusion polypeptides.

IPC Classes  ?

  • C07K 14/52 - CytokinesLymphokinesInterferons
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61P 35/00 - Antineoplastic agents

32.

NUCLEIC ACID VACCINATION USING NEO-EPITOPE ENCODING CONSTRUCTS

      
Document Number 03161242
Status Pending
Filing Date 2020-12-18
Open to Public Date 2021-06-24
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Rono, Birgitte
  • Kringelum, Jens Vindahl
  • Sorensen, Anders Bundgard
  • Trolle, Thomas
  • Friis, Stine

Abstract

The disclosure provides novel means and methods for DNA vaccination that targets cancer. In particular is provided a method for anti-cancer vaccination using a plasmid-based vaccine comprising regions encoding neo-epitopes.

IPC Classes  ?

  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

33.

Staphylococcus aureus

      
Application Number 16887611
Grant Number 11052145
Status In Force
Filing Date 2020-05-29
First Publication Date 2020-10-01
Grant Date 2021-07-06
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

S. aureus infections. Also disclosed are nucleic acids encoding the proteins and methods of use of these nucleic acids.

IPC Classes  ?

  • A61K 39/085 - Staphylococcus
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

34.

NUCLEIC ACID VACCINATION USING NEO-EPITOPE ENCODING CONSTRUCTS

      
Document Number 03131824
Status Pending
Filing Date 2020-03-11
Open to Public Date 2020-09-17
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Rono, Birgitte
  • Kringelum, Jens
  • Sorensen, Anders Bundgard
  • Trolle, Thomas

Abstract

The disclosure provides means and methods for DNA vaccination that target cancer. In particular is provided a method for anti-cancer vaccination using a plasmid based vaccine comprising regions encoding neo-epitopes and comprising amphiphilic block copolymers such as poloxamer and poloxamine agents.

IPC Classes  ?

  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

35.

VACCINES TARGETING NEOEPITOPES

      
Document Number 03124905
Status Pending
Filing Date 2020-01-03
Open to Public Date 2020-07-09
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Kringelum, Jens
  • Sorensen, Anders Bundgard
  • Rono, Birgitte
  • Petersen, Nadia Viborg

Abstract

The present invention provides methods of vaccination utilising a cationic liposomal adjuvant admixed with at least one neoepitope and a solvent. Also provided are unit dosages and compositions for use in the methods.

IPC Classes  ?

  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

36.

Staphylococcus aureus

      
Application Number 16600031
Grant Number 11807669
Status In Force
Filing Date 2019-10-11
First Publication Date 2020-01-30
Grant Date 2023-11-07
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

Staphylococcus aureus as well as therapeutic and diagnostic uses of the proteins and nucleic acids.

IPC Classes  ?

  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • A61K 39/085 - Staphylococcus
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

37.

Pseudomonas aeruginosa

      
Application Number 16473443
Grant Number 11718648
Status In Force
Filing Date 2018-01-05
First Publication Date 2019-10-31
Grant Date 2023-08-08
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

Pseudomonas aeruginosa using the proteins, nucleic acids, vectors or transformed cells.

IPC Classes  ?

  • C07K 14/21 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Pseudomonadaceae (F)
  • A61P 31/04 - Antibacterial agents
  • A61K 39/104 - Pseudomonas
  • C07K 14/33 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Clostridium (G)
  • C07K 14/34 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Corynebacterium (G)
  • C07K 14/435 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

38.

S. aureus

      
Application Number 16319729
Grant Number 11414464
Status In Force
Filing Date 2017-07-24
First Publication Date 2019-08-08
Grant Date 2022-08-16
Owner Evaxion Biotech A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm
  • Kringelum, Jens

Abstract

S. aureus infection. Also disclosed are compositions, methods of treatment and prophylaxis, nucleic acids and vectors comprising the nucleic acids.

IPC Classes  ?

  • A61K 39/085 - Staphylococcus
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • A61P 31/04 - Antibacterial agents

39.

Staphylococcus aureus

      
Application Number 16078963
Grant Number 10946084
Status In Force
Filing Date 2017-02-22
First Publication Date 2019-02-14
Grant Date 2021-03-16
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

Staphylococcus aureus as well as therapeutic and diagnostic uses of the proteins and nucleic acids.

IPC Classes  ?

  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • A61K 39/02 - Bacterial antigens
  • A61K 39/085 - Staphylococcus
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • A61P 31/04 - Antibacterial agents
  • A61K 39/39 - Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants

40.

Klebsiella pneumoniae

      
Application Number 15542580
Grant Number 10434162
Status In Force
Filing Date 2016-01-12
First Publication Date 2019-01-17
Grant Date 2019-10-08
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

Klebsiella pneumonia as well as therapeutic and diagnostic uses of the proteins and nucleic acids.

IPC Classes  ?

  • C07K 14/26 - Klebsiella (G)
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • A61K 38/03 - Peptides having up to 20 amino acids in an undefined or only partially defined sequenceDerivatives thereof
  • A61K 38/16 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof
  • A61K 39/108 - EscherichiaKlebsiella
  • C12N 15/79 - Vectors or expression systems specially adapted for eukaryotic hosts
  • G01N 33/569 - ImmunoassayBiospecific binding assayMaterials therefor for microorganisms, e.g. protozoa, bacteria, viruses
  • C12N 15/70 - Vectors or expression systems specially adapted for E. coli
  • C12N 15/75 - Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus

41.

staphylococcus aureus

      
Application Number 16023741
Grant Number 10675340
Status In Force
Filing Date 2018-06-29
First Publication Date 2018-10-18
Grant Date 2020-06-09
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

S. aureus infections. Also disclosed are nucleic acids encoding the proteins and methods of use of these nucleic acids.

IPC Classes  ?

  • A61K 39/085 - Staphylococcus
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

42.

Staphylococcus aureus

      
Application Number 15387814
Grant Number 10034928
Status In Force
Filing Date 2016-12-22
First Publication Date 2017-04-13
Grant Date 2018-07-31
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

S. aureus infections. Also disclosed are nucleic acids encoding the proteins and methods of use of these nucleic acids.

IPC Classes  ?

  • A61K 39/085 - Staphylococcus
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • C12Q 1/689 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria

43.

Staphylococcus aureus

      
Application Number 14802602
Grant Number 09534022
Status In Force
Filing Date 2015-07-17
First Publication Date 2015-11-12
Grant Date 2017-01-03
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas Holm

Abstract

S. aureus infections. Also disclosed are nucleic acids encoding the proteins and methods of use of these nucleic acids.

IPC Classes  ?

  • A61K 39/085 - Staphylococcus
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • C07K 16/12 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from bacteria
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies

44.

Staphylococcus aureus

      
Application Number 14110475
Grant Number 09085631
Status In Force
Filing Date 2012-04-03
First Publication Date 2014-03-13
Grant Date 2015-07-21
Owner EVAXION BIOTECH A/S (Denmark)
Inventor
  • Møller, Niels Iversen
  • Mattsson, Andreas

Abstract

S. aureus infections. Also disclosed are nucleic acid encoding the proteins and methods of use of these nucleic acids.

IPC Classes  ?

  • A61K 39/085 - Staphylococcus
  • A61K 39/02 - Bacterial antigens
  • C07K 14/31 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
  • C07K 7/00 - Peptides having 5 to 20 amino acids in a fully defined sequenceDerivatives thereof
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies