05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations for the treatment of early stages of traumatic or acute vascular injury, namely, cerebrovascular accidents and spinal cord trauma; pharmaceutical preparations for the treatment of diseases and lesions of the nervous system, the neurological system, and spinal cord
3.
Heat-sterilized formulation comprising chitosan and process of preparation thereof
The present invention relates to a heat-sterilized aqueous composition comprising a solubilized chitosan and glycerol. It also relates to a process of preparation of the same, as well as the use thereof, including compositions useful for the prevention and treatment of dry eye syndrome and arthritic diseases or disorders.
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical and veterinary products; sanitary products
for medical purposes; chemical preparations for medical or
veterinary use; pharmaceutical products for the treatment
of neuronal diseases and diseases of the central or
peripheral nervous system. Scientific and technological services as well as research
and design services relating thereto; scientific research
for medical purposes; scientific research for medical
purposes in the field of neuronal diseases and diseases of
the central or peripheral nervous system; pharmaceutical
research and development services; pharmaceutical research
and development in the field of neuronal diseases and
diseases of the central and peripheral nervous system.
The present invention relates to a heat-sterilized aqueous composition comprising a solubilized chitosan and glycerol. It also relates to a process of preparation of the same, as well as the use thereof, including compositions useful for the prevention and treatment of dry eye syndrome and arthritic diseases or disorders.
The present invention relates to a heat-sterilized aqueous composition comprising a solubilized chitosan and glycerol. It also relates to a process of preparation of the same, as well as the use thereof, including compositions useful for the prevention and treatment of dry eye syndrome and arthritic diseases or disorders.
C08J 3/03 - Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
The present invention relates to a heat-sterilized aqueous composition comprising a solubilized chitosan and glycerol. It also relates to a process of preparation of the same, as well as the use thereof, including compositions useful for the prevention and treatment of dry eye syndrome and arthritic diseases or disorders.
A process for preparing pure monosialoganglioside GM1 in the form of its sodium salt. There is provided a process for the isolation and purification of monosialoganglioside GM1 comprising (a) separation of GM1 from a lipidic mixture containing the monosialoganglioside GM1 as the main ganglioside component by ion exchange column-chromatography using an eluent comprising potassium or caesium ions, (b) recovery of the solute from the eluted solution, (c) diafiltration of an aqueous solution of the recovered solute, and (d) second diafiltration after the addition of 1 M NaCl, and recovering GM1. The purity level of GM1 obtained is higher than 99.0%.
A61K 31/7032 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyl-diacylglycerides, lactobionic acid, gangliosides
A61P 25/00 - Drugs for disorders of the nervous system
C07H 15/10 - Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of a saccharide radical containing unsaturated carbon-to-carbon bonds
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Cosmetic preparations for skin care. Pharmaceutical preparations; healthcare preparations;
medicated preparations for the support of wound healing;
sanitary preparations for medical purposes; plasters and
pads for medical purposes, medical dressings; impregnated
tissues and cloths for surgical and medical purposes;
medicated textiles for wound treatment.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical preparations; healthcare preparations;
sanitary preparations for medical purposes; plasters and
pads for medical purposes, medical dressings; medical
preparations for articular cartilage regeneration; tissues
and cloths for surgical and medical purposes; surgical
implants (included in this class). Surgical implants (included in this class).
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical and veterinary preparations; sanitary
preparations for medical purposes; plasters, materials for
dressings; disinfectants; ophthalmic preparations;
pharmaceutical preparations for treating arthritic illness
and disorder; pharmaceutical preparations against
osteoarthritis; pharmaceutical and medical preparations and
substances for repairing, regenerating and treating bone and
cartilage tissue; surgical cloth. Surgical, medical and veterinary instruments and apparatus;
orthopedic articles; surgical implants [artificial
materials]; artificial bone and joint implants; prostheses
for surgical implantations; bone and joint prostheses for
surgical implantations; artificial implants and prostheses
for inserting, by means of surgery, in the damaged cartilage
surface of the knee.
C07C 309/00 - Sulfonic acidsHalides, esters, or anhydrides thereof
C07C 309/60 - Sulfonic acids having sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing carboxyl groups bound to the carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
Pharmaceutical preparations; surgical implants; surgical
implants derived from biological tissue; surgical implants
in the form of biological collagen membranes for dental and
medical purposes; materials for surgical implants in dental
and orthopedic surgery; biocompatible collagen membrane for
covering and regenerating bone defects through surgery. Surgical implants of synthetic materials; surgical implants
containing collagen; biocompatible collagen membrane for
recovering and regenerating cartilage defects through
surgery; material for bone implants; material for implants
in dental and orthopedic surgery.
The present invention relates to wound dressings having a wound contacting layer that contains a wound healing composition and which is adapted to maintain a temperature different from ambient, for example achieve and maintain a heat-absorbing effect on the underlying tissues. The specific physico-chemical structure of the devices of the invention allows fluid containment and absorption of wound secretions whilst avoiding skin macerations.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations; pharmaceutical preparations for
the treatment of diseases and lesions of the nervous system,
the neurological system, and spinal cord.
There is provided a process for the purification of crude diacerein, wherein diacerein is crystallized from 1-methyl-2-pyrrolidone, or a mixture of 1-methyl-2- pyrrolidone and a co-solvent.
Process for the preparation of aloe-emodin from aloin comprising oxidizing aloin by treatment with an oxygen containing gas, in an acid reaction medium, in the presence of a copper salt catalyst.
Process for the preparation of rhein or diacerein comprising oxidising aloe-emodin with hydrogen peroxide or an alkali-metal peroxide oxidant in a basic reaction medium, optionally in the presence of an organic solvent, to obtain rhein. Optionally followed by acetylating the rhein thus obtained using an acetylating agent to obtain diacerein.
C07C 51/285 - Preparation of carboxylic acids or their salts, halides, or anhydrides by oxidation with peroxy-compounds
C07C 65/40 - Compounds having carboxyl groups bound to carbon atoms of six-membered aromatic rings and containing any of the groups OH, O-metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups
Compounds that may have anti-inflammatory activity have the general formula (I): Wherein R1, R2, R3 are each independently H or a C1-4 alkyl group or a C2-4 acyl group; R4 and R5 are each independently H or a group of formula -SO3R6, wherein R6 is H or a C1-4 alkyl group or a C2-4 acyl group; with the proviso that at least one of R4 and R5 is a group of formula -SO3R6, or a pharmaceutically acceptable salt thereof.
C07C 317/46 - SulfonesSulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
Compounds that may have anti-inflammatory activity have the general formula (I): Wherein R1, R2, R3 are each independently H or a C1-4 alkyl group or a C2-4 acyl group; R4 and R5 are each independently H or a group of formula -SO3R6, wherein R6 is H or a C1-4 alkyl group or a C2-4 acyl group; with the proviso that at least one of R4 and R5 is a group of formula -SO3R6, or a pharmaceutically acceptable salt thereof.
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
C07C 317/46 - SulfonesSulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound oxygen atoms
23.
Process for obtaining pure monosialoganglioside GM1 for medical use
A process for preparing pure monosialoganglioside GM1 in the form of its sodium salt. There is provided a process for the isolation and purification of monosialoganglioside GM1 comprising (a) separation of GM1 from a lipidic mixture containing the monosialoganglioside GM1 as the main ganglioside component by ion exchange column-chromatography using an eluent comprising potassium or caesium ions, (b) recovery of the solute from the eluted solution, (c) diafiltration of an aqueous solution of the recovered solute, and (d) second diafiltration after the addition of 1 M NaCl, and recovering GM1. The purity level of GM1 obtained is higher than 99.0%.
C07H 17/00 - Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
C07H 17/02 - Heterocyclic radicals containing only nitrogen as ring hetero atoms
A01N 43/04 - Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atom with one hetero atom
Disclosed is a device and method which provide a surgical therapy for in situ treatment and repair of intra-articular cartilage lesions and/or defects. The device is an implantable laminate cartilage repair patch which is bio-compatible and physiologically absorbable. The cartilage repair patch has a first outer cell occlusive layer; a second outer, cell porous layer adapted to be disposed proximate a subchondral bone wound site; and a cartilagenic matrix disposed between the first and second layers. The cartilagenic matrix is a sink for diffusion of autologous stem cells and includes chemical components promoting generation of hyaline-like cartilage in the presence of the autologous stem cells. The method of the present invention provides the autologous compositions, which when used in combination with the repair patch provides a therapeutic system to regenerate replacement hyaline-like intraarticular cartilage.
The aqueous thermosetting neutralized chitosan composition, forming a phosphate-free transparent hydrogel at a temperature higher than 5°C, comprises 0.1 to 5.0 w/w %, based on the total composition, of a reacetylated chitosan having a molecular weight of not smaller than 100 kDa and a deacetylation degree of 40 to 70 %, neutralized with an hydroxylated base, and 1 to 30 w/w %, based on the total composition, of a complexing agent selected from polyoses and polyols derived from polyoses. Said composition is useful for the preparation of an injectable formulation.
05 - Pharmaceutical, veterinary and sanitary products
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Pharmaceutical preparations; dietetic substances adapted for
medical use; nutritional additives adapted for medical use. Nutritional supplements not adapted for medical use made
with proteins, fats, fatty acids, with added vitamins,
minerals, trace minerals, either individually, or in
combination, included in this class. Nutritional supplements not adapted for medical use made
with carbohydrates, dietary fibres, with added vitamins,
minerals, trace minerals, either individually, or in
combination, included in this class.
A process for preparing aloe-emodin from aloin by oxidizing aloin by treatment with an oxygen-containing gas in the presence of an acid. The aloe-emodin may be used for the production of rhein and diacerein by oxidizing aloe-emodin by treatment with a chromium-free oxidizing medium to obtain rhein and purifying the rhein obtained. The rhein may be acetylated to obtain diacerein.
C07C 51/27 - Preparation of carboxylic acids or their salts, halides, or anhydrides by oxidation with oxides of nitrogen or nitrogen-containing mineral acids
C07C 67/08 - Preparation of carboxylic acid esters by reacting carboxylic acids or symmetrical anhydrides with the hydroxy or O-metal group of organic compounds
C07C 69/16 - Acetic acid esters of dihydroxylic compounds
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations as well as health care
preparations; dietetic substances adapted for medical use;
dietary supplements (included in this class).
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical preparations as well as health care
preparations; dietetic substances adapted for medical use;
dietary supplements (included in this class).
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Produits pharmaceutiques, vétérinaires et hygiéniques;
substances diététiques à usage médical, aliments pour bébés;
emplâtres, matériel pour pansements; matières pour plomber
les dents et pour empreintes dentaires; désinfectants;
produits pour la destruction des animaux nuisibles;
fongicides, herbicides.
05 - Pharmaceutical, veterinary and sanitary products
Goods & Services
Pharmaceutical, veterinary and sanitary products; dietetic
substances for medical use, baby food; plasters, materials
for dressings; materials for filling teeth and dental wax;
disinfectants; preparations for destroying vermin;
fungicides, herbicides.
