The disclosed pathology slides may include a substantially transparent substrate that includes a top major surface, at least two regions on the top major surface of the substantially transparent substrate having a size sufficient for receiving at least two respective biopsy tissue sample sections on the substantially transparent substrate, and at least one visibly perceptible separation mark on or in the substantially transparent substrate separating the at least two regions from each other. Various other related methods and systems are also disclosed.
Tissue sample management systems include a central network, a medical professional system, and a pathology lab system for processing a tissue sample in a matrix having a sectionable code. At least the pathology lab system includes at least one imaging device, and the central network is configured to process images from the at least one imaging device to identify and record at least the sectionable code of the matrix. Methods for tissue sample processing include providing a matrix having a sectionable code and measurement marks, the matrix for receiving a tissue sample, and identifying the sectionable code from an image taken of the tissue sample in the matrix. Tissue sample-receiving matrices include a sectionable alphanumeric code or bar code, a tissue sample receptacle, and measurement marks formed along a sidewall thereof. The matrices include one or more proteins and one or more lipids.
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
The disclosed methods for preparing cytological samples may include placing a cytological sample in a concave filter in a filtration system, applying a negative pressure to an outer side of the concave filter with a vacuum device to withdraw a liquid from the cytological sample, applying a sectionable matrix material over the filtered cellular material within the concave filter, and removing an assembly including the filtered cellular material and the sectionable matrix material from the filtration system. Various other related methods, systems, and materials are also disclosed.
A cooling device suitable for cooling paraffin tissue blocks with little or no moisture artefacts, as well as the use thereof to obtain good quality serial sections for microscope slides. The slides can be used in histology and anatomical pathology, for example. The cooling device may include a cold plate, a lid, and a sheet of insulating material over the cold plate.
F25D 17/06 - Arrangements for circulating cooling fluidsArrangements for circulating gas, e.g. air, within refrigerated spaces for circulating gas, e.g. by natural convection by forced circulation
F25D 23/10 - Arrangements for mounting in particular locations, e.g. for built-in type, for corner type
A cooling device suitable for cooling paraffin tissue blocks with little or no moisture artefacts, as well as the use thereof to obtain good quality serial sections for microscope slides. The slides can be used in histology and anatomical pathology, for example. The cooling device may include a cold plate, a lid, and a perforated sheet of insulating material over the cold plate. The perforated sheet of insulating material may inhibit the freezing of the paraffin block(s) by the cold plate and may enable the paraffin block(s) to cool to a temperature above the temperature of the cold plate surface. For example, because of the small volume of air within the enclosure (e.g., between the lid and the cold plate) of the device, the paraffin blocks may cool relatively quickly and then stabilize to a temperature in a desired range for microtome sectioning.
B01L 7/00 - Heating or cooling apparatusHeat insulating devices
B25B 21/02 - Portable power-driven screw or nut setting or loosening toolsAttachments for drilling apparatus serving the same purpose with means for imparting impact to screwdriver blade or nut socket
The disclosed spacers for microscope slides may include a spacer body including a material configured to provide an optical focal reference for a microscope and a central opening in the spacer body sized and shaped to receive a cytological sample. The spacer body may have a thickness of about 20 μm or less. Methods of analyzing cytological samples may include disposing a cytological sample on a microscope slide adjacent to a spacer positioned on the microscope slide, focusing an optical module of a microscope to a focal plane using at least a portion of the spacer as a focal reference, and viewing the cytological sample through the optical module of the microscope at the focal plane. Various other related methods, systems, and devices are also disclosed.
A tamper for making paraffin blocks for histology may include a pliable tamper head and a handle. The handle may be permanently or removably attached to the tamper by using screws, magnets, or the like. The tamper may be made from a pliable material, such as a silicone rubber, with improved thermal transfer and high latent heat. In use, the tamper may be warmed in advance to a working temperature by placing the tamper on a hot plate of the embedding station or on a dedicated smaller hot plate. Alternatively, the tamper may be heated with an electric resistive element, a thermoelectric device, or an electric induction coil.
A tamper for making paraffin blocks for histology may include a pliable tamper head and a handle. The handle may be permanently or removably attached to the tamper by using screws, magnets, or the like. The tamper may be made from a pliable material, such as a silicone rubber, with improved thermal transfer and high latent heat. In use, the tamper may be warmed in advance to a working temperature by placing the tamper on a hot plate of the embedding station or on a dedicated smaller hot plate. Alternatively, the tamper may be heated with an electric resistive element, a thermoelectric device, or an electric induction coil.
Tissue sample cassettes for receiving tissue samples include an upper tray including compartments separated by dividers, a lower tray coupled to the upper tray and having a central recess, and an absorbent material located in the recess of the lower tray. Related systems and methods for automated gross processing of tissue samples are also disclosed.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01B 11/02 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness
G01B 11/06 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness for measuring thickness
G01B 11/28 - Measuring arrangements characterised by the use of optical techniques for measuring areas
The disclosed computer-implemented method may include (1) receiving an image of a section of a sectionable tissue sample block, the image including image data of, embedded into the section of the sectionable tissue sample block, (A) a section of a tissue sample, and (B) a section of a sectionable fiducial marker, (2) determining an attribute of the section of the sectionable fiducial marker from the received image of the section of the sectionable tissue sample block, and (3) executing a tissue sample management action based on the determined attribute of the section of the sectionable fiducial marker. Various other methods, systems, apparatuses, and computer-readable media are also disclosed.
The disclosed computer-implemented method may include (1) receiving an image of a section of a sectionable tissue sample block, the image including image data of, embedded into the section of the sectionable tissue sample block, (A) a section of a tissue sample, and (B) a section of a sectionable fiducial marker, (2) determining an attribute of the section of the sectionable fiducial marker from the received image of the section of the sectionable tissue sample block, and (3) executing a tissue sample management action based on the determined attribute of the section of the sectionable fiducial marker. Various other methods, systems, apparatuses, and computer-readable media are also disclosed.
The disclosed computer-implemented method may include (1) receiving an image of a section of a sectionable tissue sample block, the image including image data of, embedded into the section of the sectionable tissue sample block, (A) a section of a tissue sample, and (B) a section of a sectionable fiducial marker, (2) determining an attribute of the section of the sectionable fiducial marker from the received image of the section of the sectionable tissue sample block, and (3) executing a tissue sample management action based on the determined attribute of the section of the sectionable fiducial marker. Various other methods, systems, apparatuses, and computer-readable media are also disclosed.
A custom-made matrix suitable for receiving a tissue sample is described, as well as the use thereof to obtain a multiplex histological preparation. The disclosure also relates to a multiplex biopsy array comprising tissue and/or cell samples arranged in a matrix material and to a method for the preparation of a multiplex biopsy array. Methods for preparing blocks of matrix material to be used in multiplex biopsy arrays are also described, as well as methods for loading biopsy samples in the blocks, and methods for treating and processing the blocks to form biopsy arrays. The biopsy arrays made using the block of matrix material can be used to prepare sections and slides for histological procedures, including quantitative analyses and parallel processing.
Tissue sample cassettes for receiving tissue samples include an upper tray including compartments separated by dividers, a lower tray coupled to the upper tray and having a central recess, and an absorbent material located in the recess of the lower tray. Related systems and methods for automated gross processing of tissue samples are also disclosed.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01B 11/02 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness
G01B 11/06 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness for measuring thickness
G01B 11/28 - Measuring arrangements characterised by the use of optical techniques for measuring areas
The disclosed spacers for microscope slides may include a spacer body including a material configured to provide an optical focal reference for a microscope and a central opening in the spacer body sized and shaped to receive a cytological sample. The spacer body may have a thickness of about 20 µm or less. Methods of analyzing cytological samples may include disposing a cytological sample on a microscope slide adjacent to a spacer positioned on the microscope slide, focusing an optical module of a microscope to a focal plane using at least a portion of the spacer as a focal reference, and viewing the cytological sample through the optical module of the microscope at the focal plane. Various other related methods, systems, and devices are also disclosed.
The disclosed spacers for microscope slides may include a spacer body including a material configured to provide an optical focal reference for a microscope and a central opening in the spacer body sized and shaped to receive a cytological sample. The spacer body may have a thickness of about 20 µm or less. Methods of analyzing cytological samples may include disposing a cytological sample on a microscope slide adjacent to a spacer positioned on the microscope slide, focusing an optical module of a microscope to a focal plane using at least a portion of the spacer as a focal reference, and viewing the cytological sample through the optical module of the microscope at the focal plane. Various other related methods, systems, and devices are also disclosed.
The disclosed methods for preparing cytological samples may include placing a cytological sample in a concave filter in a filtration system, applying a negative pressure to an outer side of the concave filter with a vacuum device to withdraw a liquid from the cytological sample, applying a sectionable matrix material over the filtered cellular material within the concave filter, and removing an assembly including the filtered cellular material and the sectionable matrix material from the filtration system. Various other related methods, systems, and materials are also disclosed.
A system and method for on-site biopsy management. Patient information is retrieved through a biopsy system. A name of a patient, a biopsy type, and a site of the biopsy information are communicated to a user. Confirmations are received from the user through the biopsy system of the name of the patient, the biopsy type, and the site of the biopsy. A biopsy is associated with an identifier of a container securing the biopsy in response to receiving the confirmation. The biopsy information and the patient information is linked in the biopsy system. The linking is performed at a location the biopsy is performed.
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
A61B 10/02 - Instruments for taking cell samples or for biopsy
G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
G16H 30/00 - ICT specially adapted for the handling or processing of medical images
G16H 30/20 - ICT specially adapted for the handling or processing of medical images for handling medical images, e.g. DICOM, HL7 or PACS
G06V 20/69 - Microscopic objects, e.g. biological cells or cellular parts
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 70/60 - ICT specially adapted for the handling or processing of medical references relating to pathologies
A custom-made matrix suitable for receiving a tissue sample is described, as well as the use thereof to obtain a multiplex histological preparation. The disclosure also relates to a multiplex biopsy array comprising tissue and/or cell samples arranged in a matrix material and to a method for the preparation of a multiplex biopsy array. Methods for preparing blocks of matrix material to be used in multiplex biopsy arrays are also described, as well as methods for loading biopsy samples in the blocks, and methods for treating and processing the blocks to form biopsy arrays. The biopsy arrays made using the block of matrix material can be used to prepare sections and slides for histological procedures, including quantitative analyses and parallel processing.
Tissue sample management systems include a central network, a medical professional system, and a pathology lab system for processing a tissue sample in a matrix having a sectionable code. At least the pathology lab system includes at least one imaging device, and the central network is configured to process images from the at least one imaging device to identify and record at least the sectionable code of the matrix. Methods for tissue sample processing include providing a matrix having a sectionable code and measurement marks, the matrix for receiving a tissue sample, and identifying the sectionable code from an image taken of the tissue sample in the matrix. Tissue sample-receiving matrices include a sectionable alphanumeric code or bar code, a tissue sample receptacle, and measurement marks formed along a sidewall thereof. The matrices include one or more proteins and one or more lipids.
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
The disclosed pathology slides may include a substantially transparent substrate that includes a top major surface, at least two regions on the top major surface of the substantially transparent substrate having a size sufficient for receiving at least two respective biopsy tissue sample sections on the substantially transparent substrate, and at least one visibly perceptible separation mark on or in the substantially transparent substrate separating the at least two regions from each other. Various other related methods and systems are also disclosed.
The disclosed pathology slides may include a substantially transparent substrate that includes a top major surface, at least two regions on the top major surface of the substantially transparent substrate having a size sufficient for receiving at least two respective biopsy tissue sample sections on the substantially transparent substrate, and at least one visibly perceptible separation mark on or in the substantially transparent substrate separating the at least two regions from each other. Various other related methods and systems are also disclosed.
The disclosed methods for preparing cytological samples may include placing a cytological sample in a concave filter in a filtration system, applying a negative pressure to an outer side of the concave filter with a vacuum device to withdraw a liquid from the cytological sample, applying a sectionable matrix material over the filtered cellular material within the concave filter, and removing an assembly including the filtered cellular material and the sectionable matrix material from the filtration system. Various other related methods, systems, and materials are also disclosed.
The disclosed methods for preparing cytological samples may include placing a cytological sample in a concave filter in a filtration system, applying a negative pressure to an outer side of the concave filter with a vacuum device to withdraw a liquid from the cytological sample, applying a sectionable matrix material over the filtered cellular material within the concave filter, and removing an assembly including the filtered cellular material and the sectionable matrix material from the filtration system. Various other related methods, systems, and materials are also disclosed.
The disclosed methods for preparing cytological samples may include placing a cytological sample in a concave filter in a filtration system, applying a negative pressure to an outer side of the concave filter with a vacuum device to withdraw a liquid from the cytological sample, applying a sectionable matrix material over the filtered cellular material within the concave filter, and removing an assembly including the filtered cellular material and the sectionable matrix material from the filtration system. Various other related methods, systems, and materials are also disclosed.
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Bio-chips for research or scientific purposes; Diagnostic apparatus for the detection of pathogens for laboratory or research use; Downloadable medical software for digitally sharing, annotating, and reviewing pathology slides Biopsy instruments; Medical instruments for use in performing biopsies Medical laboratory services; Providing medical testing services and information in the field of cancer research and disease classification Medical services; Medical services in the field of pathology
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Bio-chips for research or scientific purposes; Diagnostic apparatus for the detection of pathogens for laboratory or research use; Downloadable medical software for digitally sharing, annotating, and reviewing pathology slides Biopsy instruments; Medical instruments for use in performing biopsies Medical laboratory services; Providing medical testing services and information in the field of cancer research and disease classification Medical services; Medical services in the field of pathology
30.
BIOPSY TISSUE SAMPLE CASSETTE AND RELATED SYSTEMS AND METHODS
Tissue sample cassettes for receiving tissue samples include an upper tray including compartments separated by dividers, a lower tray coupled to the upper tray and having a central recess, and an absorbent material located in the recess of the lower tray. Related systems and methods for automated gross processing of tissue samples are also disclosed.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
Tissue sample cassettes for receiving tissue samples include an upper tray including compartments separated by dividers, a lower tray coupled to the upper tray and having a central recess, and an absorbent material located in the recess of the lower tray. Related systems and methods for automated gross processing of tissue samples are also disclosed.
Tissue sample cassettes for receiving tissue samples include an upper tray including compartments separated by dividers, a lower tray coupled to the upper tray and having a central recess, and an absorbent material located in the recess of the lower tray. Related systems and methods for automated gross processing of tissue samples are also disclosed.
G01N 1/36 - Embedding or analogous mounting of samples
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G01B 11/02 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness
G01B 11/06 - Measuring arrangements characterised by the use of optical techniques for measuring length, width, or thickness for measuring thickness
G01B 11/28 - Measuring arrangements characterised by the use of optical techniques for measuring areas
G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
Tissue sample management systems include a central network, a medical professional system, and a pathology lab system for processing a tissue sample in a matrix having a sectionable code. At least the pathology lab system includes at least one imaging device, and the central network is configured to process images from the at least one imaging device to identify and record at least the sectionable code of the matrix. Methods for tissue sample processing include providing a matrix having a sectionable code and measurement marks, the matrix for receiving a tissue sample, and identifying the sectionable code from an image taken of the tissue sample in the matrix. Tissue sample-receiving matrices include a sectionable alphanumeric code or bar code, a tissue sample receptacle, and measurement marks formed along a sidewall thereof. The matrices include one or more proteins and one or more lipids.
Tissue sample management systems include a central network, a medical professional system, and a pathology lab system for processing a tissue sample in a matrix having a sectionable code. At least the pathology lab system includes at least one imaging device, and the central network is configured to process images from the at least one imaging device to identify and record at least the sectionable code of the matrix. Methods for tissue sample processing include providing a matrix having a sectionable code and measurement marks, the matrix for receiving a tissue sample, and identifying the sectionable code from an image taken of the tissue sample in the matrix. Tissue sample-receiving matrices include a sectionable alphanumeric code or bar code, a tissue sample receptacle, and measurement marks formed along a sidewall thereof. The matrices include one or more proteins and one or more lipids.
Tissue sample management systems include a central network, a medical professional system, and a pathology lab system for processing a tissue sample in a matrix having a sectionable code. At least the pathology lab system includes at least one imaging device, and the central network is configured to process images from the at least one imaging device to identify and record at least the sectionable code of the matrix. Methods for tissue sample processing include providing a matrix having a sectionable code and measurement marks, the matrix for receiving a tissue sample, and identifying the sectionable code from an image taken of the tissue sample in the matrix. Tissue sample-receiving matrices include a sectionable alphanumeric code or bar code, a tissue sample receptacle, and measurement marks formed along a sidewall thereof. The matrices include one or more proteins and one or more lipids.
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G16H 80/00 - ICT specially adapted for facilitating communication between medical practitioners or patients, e.g. for collaborative diagnosis, therapy or health monitoring
G16H 30/40 - ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
G01N 35/00 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
37.
Matrix for receiving a tissue sample and use thereof
A custom-made matrix suitable for receiving a tissue sample is described, as well as the use thereof to obtain a multiplex histological preparation. The disclosure also relates to a multiplex biopsy array comprising tissue and/or cell samples arranged in a matrix material and to a method for the preparation of a multiplex biopsy array. Methods for preparing blocks of matrix material to be used in multiplex biopsy arrays are also described, as well as methods for loading biopsy samples in the blocks, and methods for treating and processing the blocks to form biopsy arrays. The biopsy arrays made using the block of matrix material can be used to prepare sections and slides for histological procedures, including quantitative analyses and parallel processing.
A system and method for on-site biopsy management. Patient information is retrieved through a biopsy system. A name of a patient, a biopsy type, and a site of the biopsy information are communicated to a user. Confirmations are received from the user through the biopsy system of the name of the patient, the biopsy type, and the site of the biopsy. A biopsy is associated with an identifier of a container securing the biopsy in response to receiving the confirmation. The biopsy information and the patient information is linked in the biopsy system. The linking is performed at a location the biopsy is performed.
G16H 10/40 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for data related to laboratory analysis, e.g. patient specimen analysis
A61B 10/00 - Instruments for taking body samples for diagnostic purposesOther methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determinationThroat striking implements
G16H 30/00 - ICT specially adapted for the handling or processing of medical images
G16H 50/20 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems
A61B 10/02 - Instruments for taking cell samples or for biopsy
G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
G16H 10/60 - ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
39.
Matrix for receiving a tissue sample and use thereof
A custom-made matrix suitable for receiving a tissue sample is described, as well as the use thereof to obtain a multiplex histological preparation. The disclosure also relates to a multiplex biopsy array comprising tissue and/or cell samples arranged in a matrix material and to a method for the preparation of a multiplex biopsy array. Methods for preparing blocks of matrix material to be used in multiplex biopsy arrays are also described, as well as methods for loading biopsy samples in the blocks, and methods for treating and processing the blocks to form biopsy arrays. The biopsy arrays made using the block of matrix material can be used to prepare sections and slides for histological procedures, including quantitative analyzes and parallel processing.
