LensGen, Inc.

United States of America

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Before 2020 25
IPC Class
A61F 2/16 - Intraocular lenses 30
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges 5
A61F 2/14 - Eye parts, e.g. lenses or corneal implantsArtificial eyes 4
B29D 11/02 - Artificial eyes from organic plastic material 3
C08G 77/24 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen halogen-containing groups 3
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NICE Class
10 - Medical apparatus and instruments 3
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services 1
Status
Pending 4
Registered / In Force 33

1.

FLUID LENS COMPONENT FOR INTRAOCULAR LENS AND METHODS OF PREPARING THE SAME

      
Application Number 17784065
Status Pending
Filing Date 2020-12-09
First Publication Date 2023-02-09
Owner LensGen, Inc. (USA)
Inventor
  • Silvestrini, Thomas
  • Nguyen, Kim Van Thuy
  • Lilly, Richard S.
  • Ingram, Richard James
  • Brady, Daniel

Abstract

An intraocular device that includes a fluid lens is provided. The fluid lens has an anterior side and posterior side that can be coupled together to form a closed cavity therebetween that can be filled with a liquid material. A channel can be formed in the posterior side that is configured to receive a joining substance that bonds the anterior side to the posterior side and inhibit the unintended spread of the joining substance. A syringe can be extended through a port in the fluid lens to flow liquid material into the closed cavity. Subsequently, a plug can be inserted into the port to prevent the escape of the liquid material.

IPC Classes  ?

2.

SILICONE OIL TERPOLYMER FOR USE IN INTRAOCULAR LENS DEVICES

      
Application Number 17755773
Status Pending
Filing Date 2020-11-05
First Publication Date 2022-12-01
Owner LENSGEN, INC. (USA)
Inventor
  • Silvestrini, Thomas A.
  • Yacoub, Kevin

Abstract

A halosilicone oil in the form of an uncrosslinked terpolymer represented by the following Formula (I): A halosilicone oil in the form of an uncrosslinked terpolymer represented by the following Formula (I): A halosilicone oil in the form of an uncrosslinked terpolymer represented by the following Formula (I): is disclosed, wherein at least one block forming component includes a halogenated, preferably fluorinated, substituent such as 2,2,2-trifluoroethyl or 3,3,3-trifluoropropyl. In some implementations, at least one block forming component also includes an aryl group, such as phenyl, that raises the refractive index of the polymer. In some implementations, the halosilicone oil is incorporated into an intraocular lens.

IPC Classes  ?

  • C08G 77/24 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen halogen-containing groups
  • A61F 2/16 - Intraocular lenses

3.

Accommodating intraocular lens device

      
Application Number 17720592
Grant Number 11826246
Status In Force
Filing Date 2022-04-14
First Publication Date 2022-10-27
Grant Date 2023-11-28
Owner LensGen, Inc (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

IPC Classes  ?

4.

Two-part accommodating intraocular lens device

      
Application Number 17514717
Grant Number 11471273
Status In Force
Filing Date 2021-10-29
First Publication Date 2022-02-17
Grant Date 2022-10-18
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61F 2/14 - Eye parts, e.g. lenses or corneal implantsArtificial eyes

5.

Accommodating intraocular lens device

      
Application Number 17305200
Grant Number 11471270
Status In Force
Filing Date 2021-07-01
First Publication Date 2021-12-30
Grant Date 2022-10-18
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens device is provided. The accommodating intraocular lens device comprises a base assembly and a power lens. The base assembly comprises a first open end, a second end coupled to a base lens, and a haptic surrounding a central cavity. The haptic may comprise an outer periphery, an inner surface and a height between a first edge and a second edge. The power lens is configured to fit within the central cavity. The power lens may comprise a first side, a second side, a peripheral edge coupling the first and second sides, and a closed cavity configured to house a fluid. The first side of the power lens may be positioned at a predetermined distance from the first edge of the haptic.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • B29D 11/02 - Artificial eyes from organic plastic material
  • G02C 7/08 - Auxiliary lensesArrangements for varying focal length
  • G02C 7/04 - Contact lenses for the eyes
  • A61F 9/007 - Methods or devices for eye surgery
  • G02B 3/14 - Fluid-filled or evacuated lenses of variable focal length

6.

Two-part accommodating intraocular lens device

      
Application Number 17315073
Grant Number 11464624
Status In Force
Filing Date 2021-05-07
First Publication Date 2021-08-26
Grant Date 2022-10-11
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61F 2/14 - Eye parts, e.g. lenses or corneal implantsArtificial eyes

7.

METHOD AND SYSTEM FOR ADJUSTING THE REFRACTIVE POWER OF AN IMPLANTED INTRAOCULAR LENS

      
Application Number 17147820
Status Pending
Filing Date 2021-01-13
First Publication Date 2021-07-08
Owner LensGen, Inc. (USA)
Inventor
  • Rao, Ramgopal
  • Silvestrini, Thomas

Abstract

A method for adjusting the refractive power of a fluid-filled intraocular lens implanted into a patients eye. The method comprises selecting a pattern to cause a flattening of the intraocular lens or an increase in curvature of the intraocular lens, and ablating the pattern, onto either an optical element of the intraocular lens or a flexible element of the intraocular lens, to alter either one or both of a refractive power and an amplitude of accommodation of the intraocular lens. The ablating occurs while the intraocular lens remains implanted in the patient's eye. The ablating maintains the integrity of a fluid-filled interior cavity defined between the optical element and the flexible element, but causes the flattening of the intraocular lens or the increase in curvature of the intraocular lens.

IPC Classes  ?

8.

FLUID LENS COMPONENT FOR INTRAOCULAR LENS AND METHODS OF PREPARING THE SAME

      
Application Number US2020064083
Publication Number 2021/119174
Status In Force
Filing Date 2020-12-09
Publication Date 2021-06-17
Owner LENSGEN, INC. (USA)
Inventor
  • Silvestrini, Thomas
  • Nguyen, Kim, Van, Thuy
  • Lilly, Richard, S.
  • Ingram, Richard, James
  • Brady, Daniel

Abstract

An intraocular device that includes a fluid lens is provided. The fluid lens has an anterior side and posterior side that can be coupled together to form a closed cavity therebetween that can be filled with a liquid material. A channel can be formed in the posterior side that is configured to receive a joining substance that bonds the anterior side to the posterior side and inhibit the unintended spread of the joining substance. A syringe can be extended through a port in the fluid lens to flow liquid material into the closed cavity. Subsequently, a plug can be inserted into the port to prevent the escape of the liquid material.

IPC Classes  ?

9.

SILICONE OIL TERPOLYMER FOR USE IN INTRAOCULAR LENS DEVICES

      
Application Number US2020059177
Publication Number 2021/092222
Status In Force
Filing Date 2020-11-05
Publication Date 2021-05-14
Owner LENSGEN, INC. (USA)
Inventor
  • Silvestrini, Thomas, A.
  • Yacoub, Kevin

Abstract

A halosilicone oil in the form of an uncrosslinked terpolymer represented by the following Formula (I): (I) is disclosed, wherein at least one block forming component includes a halogenated, preferably fluorinated, substituent such as 2,2,2-trifluoroethyl or 3,3,3-trifluoropropyl. In some implementations, at least one block forming component also includes an aryl group, such as phenyl, that raises the refractive index of the polymer. In some implementations, the halosilicone oil is incorporated into an intraocular lens.

IPC Classes  ?

  • C08L 5/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
  • C08L 71/00 - Compositions of polyethers obtained by reactions forming an ether link in the main chainCompositions of derivatives of such polymers
  • C09D 105/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof

10.

SILICONE OIL TERPOLYMER FOR USE IN INTRAOCULAR LENS DEVICES

      
Document Number 03155078
Status Pending
Filing Date 2020-11-05
Open to Public Date 2021-05-14
Owner LENSGEN, INC. (USA)
Inventor
  • Silvestrini, Thomas A.
  • Yacoub, Kevin

Abstract

A halosilicone oil in the form of an uncrosslinked terpolymer represented by the following Formula (I): (I) is disclosed, wherein at least one block forming component includes a halogenated, preferably fluorinated, substituent such as 2,2,2-trifluoroethyl or 3,3,3-trifluoropropyl. In some implementations, at least one block forming component also includes an aryl group, such as phenyl, that raises the refractive index of the polymer. In some implementations, the halosilicone oil is incorporated into an intraocular lens.

IPC Classes  ?

  • C08L 5/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof
  • C09D 105/08 - ChitinChondroitin sulfateHyaluronic acidDerivatives thereof

11.

Accommodating intraocular lens device

      
Application Number 16678318
Grant Number 11464621
Status In Force
Filing Date 2019-11-08
First Publication Date 2020-06-11
Grant Date 2022-10-11
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

IPC Classes  ?

12.

Two-part accommodating intraocular lens device

      
Application Number 16694968
Grant Number 11464622
Status In Force
Filing Date 2019-11-25
First Publication Date 2020-03-19
Grant Date 2022-10-11
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61F 2/14 - Eye parts, e.g. lenses or corneal implantsArtificial eyes

13.

INTRAOCULAR LENS DEVICES AND RELATED METHODS

      
Application Number US2019035874
Publication Number 2019/236908
Status In Force
Filing Date 2019-06-06
Publication Date 2019-12-12
Owner LENSGEN, INC. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An intraocular device that includes a has member is provided. The device can be an accommodation intraocular lens device with the base member and a power changing lens. The base member comprises an annular haptic that surrounds a central cavity having an open end. The power changing lens is configured to fit within the central cavity. The haptic comprises one or more projections, e.g., tabs that hold another device in position. In the case of the accommodating intraocular lens device, the other device is the power changing lens. The base member and the power changing lens are maintained separate until assembly in the eye of the patient. During assembly, the base member is advanced into the capsular bag of a patient through a capsulorhexis and oriented such that the open end of the central cavity faces the cornea. Subsequently, the power changing lens is advanced into the central cavity through the capsulorhexis. The one or more tabs are placed anterior of the power changing lens to secure the power changing lens within the cavity.

IPC Classes  ?

14.

NUVENE

      
Serial Number 88381699
Status Registered
Filing Date 2019-04-11
Registration Date 2022-03-22
Owner LensGen, Inc. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Intraocular lenses for the treatment of cataracts and presbyopia

15.

Two-part accommodating intraocular lens device

      
Application Number 16207658
Grant Number 11000364
Status In Force
Filing Date 2018-12-03
First Publication Date 2019-04-04
Grant Date 2021-05-11
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61F 2/14 - Eye parts, e.g. lenses or corneal implantsArtificial eyes

16.

Accommodating intraocular lens

      
Application Number 15995671
Grant Number 10772721
Status In Force
Filing Date 2018-06-01
First Publication Date 2019-01-03
Grant Date 2020-09-15
Owner LensGen, Inc. (USA)
Inventor
  • Rao, Ramgopal
  • Miller, David

Abstract

An accommodating intraocular lens (IOL) device adapted for implantation in the lens capsule of a subject's eye. The IOL device includes an anterior refractive optical element and a membrane coupled to the refractive optical element. The anterior refractive optical element and the membrane define an enclosed cavity configured to contain a fluid. At least a portion of the membrane is configured to contact a posterior area of the lens capsule adjoining the vitreous body of the subject's eye. The fluid contained in the enclosed cavity exerts a deforming or displacing force on the anterior refractive optical element in response to an anterior force exerted on the membrane by the vitreous body. The IOL device may further include a haptic system to position the anterior refractive optical element and also to engage the zonules and ciliary muscles to provide additional means for accommodation.

IPC Classes  ?

17.

Accommodating intraocular lens device

      
Application Number 16002850
Grant Number 10485654
Status In Force
Filing Date 2018-06-07
First Publication Date 2018-12-06
Grant Date 2019-11-26
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

IPC Classes  ?

18.

Accommodating intraocular lens device

      
Application Number 15996188
Grant Number 11065107
Status In Force
Filing Date 2018-06-01
First Publication Date 2018-09-27
Grant Date 2021-07-20
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens device is provided. The accommodating intraocular lens device comprises a base assembly and a power lens. The base assembly comprises a first open end, a second end coupled to a base lens, and a haptic surrounding a central cavity. The haptic may comprise an outer periphery, an inner surface and a height between a first edge and a second edge. The power lens is configured to fit within the central cavity. The power lens may comprise a first side, a second side, a peripheral edge coupling the first and second sides, and a closed cavity configured to house a fluid. The first side of the power lens may be positioned at a predetermined distance from the first edge of the haptic.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • B29D 11/02 - Artificial eyes from organic plastic material
  • G02C 7/08 - Auxiliary lensesArrangements for varying focal length
  • G02C 7/04 - Contact lenses for the eyes
  • A61F 9/007 - Methods or devices for eye surgery
  • G02B 3/14 - Fluid-filled or evacuated lenses of variable focal length

19.

LENSGEN RESTORING YOUTHFUL VISION

      
Serial Number 87959338
Status Registered
Filing Date 2018-06-12
Registration Date 2019-04-16
Owner LensGen, Inc. ()
NICE Classes  ? 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Medical information services, namely, providing information about the treatment of presbyopia; Medical information services, namely, providing medical in the field of presbyopia

20.

Lens oil having a narrow molecular weight distribution for intraocular lens devices

      
Application Number 15607305
Grant Number 10526353
Status In Force
Filing Date 2017-05-26
First Publication Date 2017-11-30
Grant Date 2020-01-07
Owner LensGen, Inc. (USA)
Inventor Silvestrini, Thomas

Abstract

A silicone oil having a mean molecular weight average greater than about 20,000 Daltons, with no more than about 3% to about 4% of the total silicone oil by weight being comprised of components having a molecular weight less than about 15,000 Daltons. In some embodiments, the silicone oil is used in intraocular lens devices.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • C07F 7/08 - Compounds having one or more C—Si linkages
  • C08G 77/14 - Polysiloxanes containing silicon bound to oxygen-containing groups
  • C08G 77/24 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen halogen-containing groups
  • C09D 183/04 - Polysiloxanes
  • C10M 107/50 - Lubricating compositions characterised by the base-material being a macromolecular compound containing silicon
  • C10M 171/04 - Specified molecular weight or molecular weight distribution
  • C08G 77/04 - Polysiloxanes
  • C08L 83/08 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen
  • C08L 83/12 - Block- or graft-copolymers containing polysiloxane sequences containing polyether sequences

21.

LENS OIL HAVING A NARROW MOLECULAR WEIGHT DISTRIBUTION FOR INTRAOCULAR LENS DEVICES

      
Application Number US2017034803
Publication Number 2017/205811
Status In Force
Filing Date 2017-05-26
Publication Date 2017-11-30
Owner LENSGEN, INC. (USA)
Inventor Silvestrini, Thomas

Abstract

A silicone oil having a mean molecular weight average greater than about 20,000 Daltons, with no more than about 3% to about 4% of the total silicone oil by weight being comprised of components having a molecular weight less than about 15,000 Daltons. In some embodiments, the silicone oil is used in intraocular lens devices.

IPC Classes  ?

22.

Polymeric material for accommodating intraocular lenses

      
Application Number 15513502
Grant Number 10647831
Status In Force
Filing Date 2015-09-22
First Publication Date 2017-08-31
Grant Date 2020-05-12
Owner LensGens, Inc. (USA)
Inventor
  • Silvestrini, Thomas
  • Yacoub, Kevin

Abstract

The disclosure relates generally to a polymeric material for use in accommodating intraocular lenses for implantation in a lens chamber of a subject's eye. The present disclosure is directed to a polymeric material which comprises a fluorosilicone polymer and a silica component. The presently disclosed polymeric material is both optically clear and has a sufficiently low Young's modulus such that it can effectively respond to the eye's natural accommodative forces and thus can be used in accommodating intraocular lenses. When used in the fabrication of an intraocular lenses, the polymeric material disclosed herein protect the physical characteristics of the lens as the added hydrophobicity of the fluorosilicone polymer allows it to effectively resist diffusion of fluid from the eye and the adhesion of biologica materials.

IPC Classes  ?

  • C08K 3/36 - Silica
  • C08G 77/20 - Polysiloxanes containing silicon bound to unsaturated aliphatic groups
  • C08G 77/24 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen halogen-containing groups
  • C08L 83/08 - Polysiloxanes containing silicon bound to organic groups containing atoms other than carbon, hydrogen, and oxygen
  • C08L 83/00 - Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen, or carbon onlyCompositions of derivatives of such polymers
  • A61F 2/16 - Intraocular lenses
  • A61L 27/18 - Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
  • C08J 3/24 - Crosslinking, e.g. vulcanising, of macromolecules
  • C08K 5/54 - Silicon-containing compounds
  • C08G 77/12 - Polysiloxanes containing silicon bound to hydrogen

23.

ACCOMMODATING INTRAOCULAR LENS DEVICE

      
Application Number US2016064491
Publication Number 2017/096087
Status In Force
Filing Date 2016-12-01
Publication Date 2017-06-08
Owner LENSGEN, INC. (USA)
Inventor
  • Brady, Daniel
  • Rao, Ramgopal
  • Silvestrini, Thomas

Abstract

An accommodating intraocular lens device is provided. The accommodating intraocular lens device comprises a base assembly and a power lens. The base assembly comprises a first open end, a second end coupled to a base lens, and a haptic surrounding a central cavity. The haptic may comprise an outer periphery, an inner surface and a height between a first edge and a second edge. The power lens is configured to fit within the central cavity. The power lens may comprise a first side, a second side, a peripheral edge coupling the first and second sides, and a closed cavity configured to house a fluid. The first side of the power lens may be positioned at a predetermined distance from the first edge of the haptic.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • B29D 11/02 - Artificial eyes from organic plastic material
  • G02B 3/12 - Fluid-filled or evacuated lenses
  • G02C 7/04 - Contact lenses for the eyes
  • G02C 7/08 - Auxiliary lensesArrangements for varying focal length

24.

Two-part accomodating intraocular lens device

      
Application Number 15144544
Grant Number 10159564
Status In Force
Filing Date 2016-05-02
First Publication Date 2016-11-03
Grant Date 2018-12-25
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

25.

Accommodating intraocular lens device

      
Application Number 15144568
Grant Number 10842616
Status In Force
Filing Date 2016-05-02
First Publication Date 2016-11-03
Grant Date 2020-11-24
Owner LensGen, Inc. (USA)
Inventor
  • Silvestrini, Thomas
  • Brady, Daniel
  • Rao, Ramgopal

Abstract

2.

IPC Classes  ?

26.

JUVENE

      
Serial Number 87102902
Status Registered
Filing Date 2016-07-13
Registration Date 2019-11-12
Owner LensGen, Inc. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Intraocular lenses for the treatment of presbyopia

27.

Accommodating intraocular lens

      
Application Number 14936544
Grant Number 10111745
Status In Force
Filing Date 2015-11-09
First Publication Date 2016-05-12
Grant Date 2018-10-30
Owner LensGen, Inc. (USA)
Inventor
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens (IOL) comprises an anterior lens, a posterior surface and an articulating member joining the anterior lens and the posterior surface to define an enclosed cavity. The articulating member comprises anterior and posterior arms coupling the anterior lens and the posterior surface, respectively. The articulating member further comprising a peripheral portion. A posterior flex region is disposed about the posterior arm and at a distance from the peripheral portion. The posterior flex region permits the flexible posterior surface to articulate relative to the posterior arm, to decrease the radius of curvature of the posterior surface as the peripheral portions on opposing sides of the IOL move toward one another in a first state and to increase the radius of curvature of the posterior surface as the peripheral portions on opposite sides of the IOL move away from one another in a second state.

IPC Classes  ?

28.

POLYMERIC MATERIAL FOR ACCOMMODATING INTRAOCULAR LENSES

      
Application Number US2015051512
Publication Number 2016/049059
Status In Force
Filing Date 2015-09-22
Publication Date 2016-03-31
Owner LENSGEN, INC. (USA)
Inventor
  • Silvestrini, Thomas
  • Yacoub, Kevin

Abstract

The disclosure relates generally to a polymeric material for use in accommodating intraocular lenses for implantation in a lens chamber of a subject's eye. The present disclosure is directed to a polymeric material which comprises a fluorosilicone polymer and a silica component. The presently disclosed polymeric material is both optically clear and has a sufficiently low Young's modulus such that it can effectively respond to the eye's natural accommodative forces and thus can be used in accommodating intraocular lenses. When used in the fabrication of an intraocular lenses, the polymeric material disclosed herein protect the physical characteristics of the lens as the added hydrophobicity of the fluorosilicone polymer allows it to effectively resist diffusion of fluid from the eye and the adhesion of biologica materials.

IPC Classes  ?

29.

Accommodating intraocular lens device

      
Application Number 14447621
Grant Number 10004596
Status In Force
Filing Date 2014-07-31
First Publication Date 2016-02-04
Grant Date 2018-06-26
Owner LensGen, Inc. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

IPC Classes  ?

30.

ACCOMMODATING INTRAOCULAR LENS DEVICE

      
Application Number US2015042513
Publication Number 2016/018932
Status In Force
Filing Date 2015-07-28
Publication Date 2016-02-04
Owner LENSGEN, INC. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens (IOL) can be implanted either alone or as part of a two-part lens assembly. The IOL comprises an optic, a flexible membrane and a peripheral edge coupling the optic and the flexible membrane. The peripheral edge comprises an external circumferential surface having a height and a force transmitting area defined along a portion of the height of the external circumferential surface. A closed volume spaces apart the optic and the flexible membrane. The optic is axially displaced and the flexible membrane changes in curvature about a central axis when a radial compressive force is applied to the force transmitting area. A volume defined by the closed volume remains fixed when the optic is axially displaced and the flexible membrane changes in curvature and/or when the radial compressive force is applied to the force transmitting area.

IPC Classes  ?

31.

ACCOMODATING INTRAOCULAR LENS DEVICE

      
Application Number US2014063473
Publication Number 2015/066502
Status In Force
Filing Date 2014-10-31
Publication Date 2015-05-07
Owner LENSGEN, INC. (USA)
Inventor
  • Silvestrini, Thomas
  • Brady, Daniel
  • Rao, Ramgopal

Abstract

An intraocular lens (IOL) device comprising a first lens, a second lens and a circumferential haptic. The first lens comprises a pair of opposing and deformable surfaces and a cavity defined therebetween. The first lens has a first lens diameter. The second lens has a second lens diameter. The circumferential haptic has an outer peripheral edge and couples the first lens and the second lens. A main IOL cavity is defined by the circumferential haptic, the first lens and the second lens. The IOL device is resiliently biased to an unaccommodated state, characterized by the IOL device having a first diameter d1 in the absence of radial compressive forces exerted on the outer peripheral edge. The IOL device actuates to an accommodated state being characterized by a second diameter d2 in response to radial compressive forces exerted on the outer peripheral edge, wherein d1 > d2.

IPC Classes  ?

32.

TWO-PART ACCOMMODATING INTRAOCULAR LENS DEVICE

      
Application Number US2014063538
Publication Number 2015/066532
Status In Force
Filing Date 2014-10-31
Publication Date 2015-05-07
Owner LENSGEN, INC. (USA)
Inventor
  • Brady, Daniel
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

A two-part accommodating intraocular lens (IOL) device for implantation in a capsular bag of a patient's eye. The IOL device includes a primary lens assembly and a power changing lens. The primary lens assembly includes a fixed lens and a peripherally disposed centration member. The centration member has a circumferential distal edge and a first coupling surface adjacent the circumferential distal edge. The power changing lens has an enclosed, fluid- or gel-filled lens cavity and haptic system disposed peripherally of the lens cavity. The haptic system has a peripheral engaging edge configured to contact the capsular bag and a second coupling surface. The first and second coupling surfaces are in sliding contact with one another to permit movement of the power changing lens relative to the primary lens assembly and also to maintain a spaced relationship between the fixed lens and the lens cavity during radial compression of the power changing lens.

IPC Classes  ?

33.

Accommodating intraocular lens

      
Application Number 13725895
Grant Number 09186244
Status In Force
Filing Date 2012-12-21
First Publication Date 2014-06-26
Grant Date 2015-11-17
Owner LensGen, Inc. (USA)
Inventor
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens (IOL) comprises a lens, a flexible surface, and an articulating member joining the lens and the flexible surface. The articulating member comprises first and second arms extending from and joined to form a peripheral portion. The peripheral portion has a length extending radially away from a point at which the first and second arms join together and a thickness that is greater than each of a thickness of the first arm and a thickness of the second arm, first and second arms coupling the lens and the flexible surface, respectively. A flex region is disposed about the second arm and at a distance from the peripheral portion. The flex region permits the flexible surface to articulate relative to the second arm. The flex region has a reduced thickness as compared to each of the second arm and the flexible surface.

IPC Classes  ?

34.

ACCOMODATING INTRAOCULAR LENS

      
Application Number US2013074817
Publication Number 2014/099630
Status In Force
Filing Date 2013-12-12
Publication Date 2014-06-26
Owner LENSGEN, INC. (USA)
Inventor
  • Silvestrini, Thomas
  • Rao, Ramgopal

Abstract

An accommodating intraocular lens (IOL) comprises an anterior lens, a posterior surface and an articulating member joining the anterior lens and the posterior surface to define an enclosed cavity. The articulating member comprises anterior and posterior arms coupling the anterior lens and the posterior surface, respectively. The articulating member further comprising a peripheral portion. A posterior flex region is disposed about the posterior arm and at a distance from the peripheral portion. The posterior flex region permits the flexible posterior surface to articulate relative to the posterior arm, to decrease the radius of curvature of the posterior surface as the peripheral portions on opposing sides of the IOC move toward one another in a first state and to increase the radius of curvature of the posterior surface as the peripheral portions on opposite sides of the IOC move away from one another in a second state.

IPC Classes  ?

35.

METHOD AND SYSTEM FOR ADJUSTING THE REFRACTIVE POWER OF AN IMPLANTED INTRAOCULAR LENS

      
Application Number US2013038943
Publication Number 2013/166068
Status In Force
Filing Date 2013-04-30
Publication Date 2013-11-07
Owner LENSGEN, INC. (USA)
Inventor
  • Rao, Ramgopal
  • Silvestrini, Thomas

Abstract

A method for adjusting the refractive power of a fluid-filled intraocular lens implanted into a patient's eye. The method comprises ablating a portion of the intraocular lens to alter either one or both of a refractive power and an amplitude of accommodation of the intraocular lens. The ablating is performed while the intraocular lens remains implanted in the patient's eye.

IPC Classes  ?

  • A61F 2/16 - Intraocular lenses
  • A61F 9/00 - Methods or devices for treatment of the eyesDevices for putting in contact-lensesDevices to correct squintingApparatus to guide the blindProtective devices for the eyes, carried on the body or in the hand
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 18/18 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves

36.

LENSGEN

      
Serial Number 86094650
Status Registered
Filing Date 2013-10-17
Registration Date 2015-03-31
Owner LensGen, Inc. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Intraocular lenses for the treatment of presbyopia

37.

ACCOMMODATING INTRAOCULAR LENS DEVICE

      
Application Number US2011034197
Publication Number 2011/137191
Status In Force
Filing Date 2011-04-27
Publication Date 2011-11-03
Owner LENSGEN, INC, (USA)
Inventor
  • Rao, Ramgopal
  • Miller, David

Abstract

An accommodating intraocular lens (IOL) device adapted for implantation in the lens capsule of a subject's eye. The IOL device includes an anterior refractive optical element and a membrane coupled to the refractive optical element. The anterior refractive optical element and the membrane define an enclosed cavity configured to contain a fluid. At least a portion of the membrane is configured to contact a posterior area of the lens capsule adjoining the vitreous body of the subject's eye. The fluid contained in the enclosed cavity exerts a deforming or displacing force on the anterior refractive optical element in response to an anterior force exerted on the membrane by the vitreous body. The IOL device may further include a haptic system to position the anterior refractive optical element and also to engage the zonules and ciliary muscles to provide additional means for accommodation.

IPC Classes  ?