CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD DE LYON 1 (France)
LES HOSPICES CIVILS DE LYON (France)
Inventor
Rosa Calatrava, Manuel, Melchior, Jean-Pierre
Terrier, Olivier
Durupt, François, Edouard, Julien
Abstract
The invention relates to mutant proteins of the fusion protein (F protein) of the Parainfluenza virus (PIV) currently recorded as type-5 PIV (PIV-5 or PIV5) and type-2 PIV (PIV-2 or PIV2). The present invention relates to products derived therefrom such as: nucleic acids, vectors, cells; fusion inhibitors of the antibody, aptamers, interfering RNA; myelomae, hybridomae, progenitor and stem cells. The present invention also relates to said mutant proteins and products derived therefrom used in medical applications and biotechnologies.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
UNIVERSITE CLAUDE BERNARD DE LYON 1 (France)
LES HOSPICES CIVILS DE LYON (France)
Inventor
Rosa Calatrava, Manuel, Melchior, Jean-Pierre
Terrier, Olivier
Durupt, François, Edouard, Julien
Abstract
The invention relates to two mutant proteins of the fusion protein (F protein) of the Parainfluenza virus (PIV) currently recorded as type-5 PFV (PIV-5 or PIV5) and type-2 PIV (PIV-2 or PIV2). The present invention relates to products derived therefrom such as: nucleic acids, vectors, cells; fusion inhibitors of the antibody, aptamers, interfering RNA; myelomae, hybridomae, progenitor and stem cells. The present invention also relates to said mutant proteins and products derived therefrom used in medical applications and biotechnologies.
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (France)
LES HOSPICES CIVILS DE LYON (France)
Inventor
Lina, Bruno
Terrier, Olivier
Thouvenot, Danielle, Françoise
Abstract
The invention relates to a phylogenetic group variant of HPIV2, in particular to a phylogenetic sub-group variant of HPIV2. The invention further relates to diagnostic means for HPIV2, taking account of said group and sub-group.
C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage