Abstract

The invention relates to δ-oxo hydrazide-hydrazone derivative compounds that show anticancer activity against breast (MCF-7) and prostate (PC-3) cancer cells, but do not show any toxicity on healthy breast epithelial cells (ME-16C) at the same dose, and their synthesis methods. When N'-(4-methoxybenzylidene)-5-oxo-5- phenylpentanehydrazide, N'-(4-methoxybenzylidene)-5-(4-chlorophenyl)-5-oxo- pentanehydrazide, N'-(4-methoxybenzylidene)-5-oxo-5-p-tolylpentanehydrazide, N'- (4-methoxybenzylidene)-5-(4-methoxyphenyl)-5-oxo-pentanehydrazide and N'-(4- methoxybenzylidene)-5-oxo-5-(thiophen-2-yl) pentanhydrazide compounds are evaluated in terms of anticancer activity, it was proven that these compounds did not show any effect against normal breast epithelial cells (ME-16C) at the same dose although these compounds showed significant inhibitory activity against breast (MCF- 7) and/or prostate (PC-3) cancer cells. The general structure of the compounds of the invention is shown by Formula (X).

IPC Classes  ?

• A61P 35/02 - Antineoplastic agents specific for leukemia
• C07D 213/86 - Hydrazides; Thio or imino analogues thereof
• C07C 243/00 - Compounds containing chains of nitrogen atoms singly-bound to each other, e.g. hydrazines, triazanes

Goods & Services

Education and training services; Arranging and conducting of conferences, congresses and seminars; Sporting and cultural activities; entertainment; ticket reservation and booking services for entertainment, sporting and cultural events, including ticket reservation and booking services for theatres, cinemas, museums and concerts; Publication and editing of printed matter, including magazines, books, newspapers, other than publicity texts; electronic publication services; Production of movie films, radio and television programs; News reporters services; photographic reporting services; Photography; Translation.

Abstract

The invention relates to granola that can be conveniently consumed at every meal and contain rosemary and olive leaf extracts being encapsulated with chitosan polymer nanoparticles with its content containing oatmeal, rice hazelnut, rice peanut, honey, water, dried banana, molasses, chocolate drops, olive oil, encapsulated rosemary extract and encapsulated olive leaf extract.

IPC Classes  ?

• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A23P 10/30 - Encapsulation of particles, e.g. foodstuff additives
• A23L 7/10 - Cereal-derived products
• A23L 7/126 - Snacks or the like obtained by binding, shaping or compacting together cereal grains or cereal pieces, e.g. cereal bars

Abstract

With its oatmeal, rice hazelnut, rice peanut, honey, water, currant, molasses, orange extract, encapsulated magnesium, and encapsulated vitamin C content, the invention relates to vitamin C and magnesium containing granola encapsulated with chitosan polymer nanoparticles that is beneficial for human health, meets the daily vitamin C and magnesium requirement of the user and can be consumed easily at every meal.

IPC Classes  ?

• A23L 33/15 - Vitamins
• A23L 7/126 - Snacks or the like obtained by binding, shaping or compacting together cereal grains or cereal pieces, e.g. cereal bars
• A23G 3/00 - Sweetmeats; Confectionery; Marzipan; Coated or filled products
• B01J 13/00 - Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons

Abstract

The invention relates to curcumin containing granola encapsulated with chitosan polymer nanoparticles, that meet the daily curcumin requirement of the user, can be easily consumed at every meal with its content of oatmeal, rice hazelnut, rice peanut, honey, water, dried coconut, dried apricot, molasses, vanilla extract, and encapsulated curcumin.

IPC Classes  ?

• A23L 33/15 - Vitamins
• A23L 7/126 - Snacks or the like obtained by binding, shaping or compacting together cereal grains or cereal pieces, e.g. cereal bars
• A23G 3/00 - Sweetmeats; Confectionery; Marzipan; Coated or filled products
• B01J 13/00 - Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons

Abstract

The invention relates to granola that can be consumed easily at every meal and contain anthocyanin that is encapsulated with chitosan polymer nanoparticles with the content of oatmeal, rice hazelnut, rice peanut, honey, water, cranberry, molasses.

IPC Classes  ?

• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A23P 10/30 - Encapsulation of particles, e.g. foodstuff additives
• A23L 7/10 - Cereal-derived products
• A23L 7/126 - Snacks or the like obtained by binding, shaping or compacting together cereal grains or cereal pieces, e.g. cereal bars