Abstract

The present invention relates to a module for optically exciting a sample volume by means of an optical chip, comprising a control unit, a holding device for an optical chip, at least one coupling unit for guiding light into the optical chip, a positioning unit designed to position the coupling unit or at least parts thereof relative to the optical chip, and at least one detection unit for capturing light from at least one thin-film waveguide of the optical chip, a signal concerning the light captured by the detection unit, in particular concerning the intensity of said light, being transmitted to the control unit, which is designed to control the at least one light source and/or the positioning unit on the basis of the signal.

IPC Classes  ?

• G02B 21/16 - Microscopes adapted for ultraviolet illumination
• G01N 21/64 - FluorescencePhosphorescence
• G02B 21/06 - Means for illuminating specimen
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes

Abstract

The present invention relates to an optoelectronic chip for receiving a sample for optical examination, having a carrier layer, a thin-film lightguide having an active region, in which the sample interacts with a guided mode of the thin-film lightguide, wherein at least one scattering structure is arranged in the active region, which scatters a part of the light guided in the thin-film lightguide, whereby a reference light field is produced. The invention further relates to an optical system having such a chip. The system is used for the marker-free analysis of particles, particularly biomolecules in their natural environment.

IPC Classes  ?

• G02B 21/16 - Microscopes adapted for ultraviolet illumination
• G01N 21/64 - FluorescencePhosphorescence
• G02B 21/30 - Base structure with heating device

Abstract

The present invention relates to an optoelectronic chip for receiving a sample in the visualization of temperature-dependent processes, having a carrier layer, a thin-film lightguide and a thin-film heating element, wherein the thin-film lightguide and the thin-film heating element are preferably arranged on sides of the carrier layer that lie opposite each other.

IPC Classes  ?

• G01N 21/64 - FluorescencePhosphorescence
• G02B 21/06 - Means for illuminating specimen
• G02B 21/30 - Base structure with heating device
• G02B 21/16 - Microscopes adapted for ultraviolet illumination
• G01N 33/557 - ImmunoassayBiospecific binding assayMaterials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction

Abstract

The present invention relates to a module for optically exciting a sample volume by means of an optical chip, comprising a control unit (1), a holding device (7) for an optical chip (6), at least one coupling unit (4, 5) for guiding light into the optical chip (6), a positioning unit (8) designed to position the coupling unit (4, 5) or at least parts thereof relative to the optical chip (6), and at least one detection unit (9, 14, 15) for capturing light from at least one thin-film waveguide of the optical chip (6), a signal concerning the light captured by the detection unit (9, 14, 15), in particular concerning the intensity of said light, being transmitted to the control unit (1), which is designed to control the at least one light source (L1-L4) and/or the positioning unit (8) on the basis of the signal.

IPC Classes  ?

• G02B 21/16 - Microscopes adapted for ultraviolet illumination
• G02B 21/34 - Microscope slides, e.g. mounting specimens on microscope slides
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
• G01N 21/64 - FluorescencePhosphorescence

Abstract

The present invention relates to an optoelectronic chip for receiving a sample in the visualization of temperature-dependent processes, comprising a carrier layer, a thin-film lightguide and a thin-film heating element, wherein the thin-film lightguide and the thin-film heating element are preferably arranged on sides of the carrier layer, which lie opposite each other.

IPC Classes  ?

• G02B 21/16 - Microscopes adapted for ultraviolet illumination
• G01N 21/64 - FluorescencePhosphorescence
• G02B 21/30 - Base structure with heating device
• C12Q 1/6825 - Nucleic acid detection involving sensors
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes
• G02B 27/56 - Optics using evanescent waves, i.e. inhomogeneous waves

Abstract

The present invention relates to an optoelectronic chip for receiving a sample for optical examination, comprising a carrier layer, a thin-film lightguide having an active region, in which the sample interacts with a guided mode of the thin-film lightguide, wherein at least one scattering structure is arranged in the active region, which scatters a part of the light guided in the thin-film lightguide, whereby a reference light field is produced. The invention further relates to an optical system comprising such a chip. The system is used for the marker-free analysis of particles, particularly biomolecules in their natural environment.

IPC Classes  ?

• G02B 27/56 - Optics using evanescent waves, i.e. inhomogeneous waves
• G02B 21/16 - Microscopes adapted for ultraviolet illumination
• G02B 21/30 - Base structure with heating device
• G01N 21/64 - FluorescencePhosphorescence
• C12Q 1/6825 - Nucleic acid detection involving sensors
• G02B 21/36 - Microscopes arranged for photographic purposes or projection purposes