A method for increasing pollination, crop quality and/or crop yield and/or seed production in agricultural or horticultural crops susceptible of pollination through invertebrates of the Apidae families (bees), in particular honey bees (Apini), bumble bees (Bombini), or stingless honey bees (Meliponini), including providing agricultural, horticultural crops, or bee-yards where bees are placed in transit prior to or after pollination, providing one or more beehives within or in the immediate vicinity of the agricultural or horticultural crops to pollinate the agricultural or horticultural crops during the pollination period of the agricultural or horticultural crops or greenhouse crops or partially covered crops, in particular tunnel crops, and administering to the beehives a pollen supplement composition.
A01K 47/06 - Other details of beehives, e.g. ventilating devices, entrances to hives, guards, partitions or bee escapes
A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
A61K 31/575 - Compounds containing cyclopenta[a]hydrophenanthrene ring systemsDerivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
The present invention relates to genetically-modified oleaginous yeasts for producing non-native sterols at commercially useful levels, especially for example in providing sterols individually or as a mixture in an artificial dietary composition for honeybees or other insects or animals. For this purpose, an oleaginous yeast, e.g. Yarrowia lipolytica, may be employed wherein the yeast has reduced production of ergosterol compared with a wild-type oleaginous yeast or is incapable of producing ergosterol and is provided with a sterol surrogate to aid growth. From such yeast, however, other yeast may be engineered which retain useful sterol production without need for a sterol surrogate, e.g. production of sterol mixtures in which 24-methylenecholesterol or campesterol is the dominant sterol.
A method for feeding invertebrates or aquaculture organisms, comprising # providing a pollen substitute composition comprising a nutritionally effective amount of isofucosterol, fucosterol or a mixture thereof; and # administering the pollen substitute composition to invertebrates or aquaculture organisms; wherein the pollen substitute composition comprises a nutritionally effective amount at least one further sterol, preferably at least two further sterols selected from the group consisting of cholesterol, 24-Methylene-cholesterol, campesterol, stigmasterol and beta-sitosterol or a physiologically available conjugate of any of these sterols.
Provided is a method for feeding invertebrates, comprising ▪ Providing a pollen substitute or supplement composition for invertebrates, in particular for honey bees and bumble bees out of yeast selected from the group consisting of S. cerevisiae, Xanthophyllomyces sp., S. japonicus or Yarrowia lipolytica, ▪ Administering the composition to invertebrates, wherein the composition is essentially free of ergosterol or zymosterol or combinations thereof.
Provided are methods for feeding invertebrates comprising: # providing a non-pollen composition comprising a nutritionally effective amount of proanthocyanidins; and # administering the non-pollen composition to invertebrates.
A01K 53/00 - Feeding or drinking appliances for bees
A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
A23K 20/121 - Heterocyclic compounds containing oxygen or sulfur as hetero atom
A23K 50/90 - Feeding-stuffs specially adapted for particular animals for insects, e.g. bees or silkworms
6.
METHODS FOR DELIVERING 24-METHYLENE CHOLESTEROL, ISOFUCOSTEROL, CHOLESTEROL OR DESMOSTEROL TO INVERTEBRATES, IN PARTICULAR HONEY BEES OR BUMBLE BEES
A method for feeding invertebrates comprising: ▪providing a composition comprising a microbial organism or parts, extracts, oils or refinements thereof; and ▪administering the composition to invertebrates wherein the microbial organism is selected from the group consisting of Saccharomyces cerevisiae, Xanthophyllomyces sp., S. japonicus or Yarrowia Hpolytica; and wherein the microbial organism has been genetically modified to produce an invertebrate nutrient selected from the group consisting of 24-methylene cholesterol, isofucosterol, cholesterol or desmosterol.
Provided is a method for feeding invertebrates or aquaculture organisms comprising: #providing a non-pollen composition comprising a nutritionally effective amount of isofucosterol, fucosterol or a mixture thereof; and #administering the non-pollen composition to invertebrates.
A method for feeding invertebrates or aquaculture organisms, comprising providing a pollen substitute composition comprising a nutritionally effective amount of isofucosterol, fucosterol or a mixture thereof; and administering the pollen substitute composition to invertebrates or aquaculture organisms; wherein the pollen substitute composition comprises a nutritionally effective amount at least one further sterol, preferably at least two further sterols selected from the group consisting of cholesterol, 24-Methylenecholesterol, campesterol, stigmasterol and beta- sitosterol or a physiologically available conjugate of any of these sterols.
A method for feeding invertebrates or aquaculture organisms, comprising • providing a pollen substitute composition comprising a nutritionally effective amount of isofucosterol, fucosterol or a mixture thereof; and • administering the pollen substitute composition to invertebrates or aquaculture organisms; wherein the pollen substitute composition comprises a nutritionally effective amount at least one further sterol, preferably at least two further sterols selected from the group consisting of cholesterol, 24-Methylenecholesterol, campesterol, stigmasterol and beta-sitosterol or a physiologically available conjugate of any of these sterols.
A method for feeding invertebrates comprising: providing a composition comprising a microbial organism or parts, extracts, oils or refinements thereof; and administering the composition to invertebrates wherein the microbial organism is selected from the group consisting of Saccharomyces cerevisiae, Xanthophyllomyces sp., S. japonicus or Yarrowia lipolytica; and wherein the microbial organism has been genetically modified to produce an invertebrate nutrient selected from the group consisting of 24-methylene cholesterol, isofucosterol, cholesterol or desmosterol
Provided is a method for feeding invertebrates or aquaculture organisms comprising: providing a non-pollen composition comprising a nutritionally effective amount of isofucosterol, fucosterol or a mixture thereof; and administering the non-pollen composition to invertebrates.
A method for feeding invertebrates comprising: ■ providing a composition comprising a microbial organism or parts, extracts, oils or refinements thereof; and ■ administering the composition to invertebrates wherein the microbial organism is selected from the group consisting of Saccharomyces cerevisiae, Xanthophyllomyces sp., S. japonicus or Yarrowia Hpolytica; and wherein the microbial organism has been genetically modified to produce an invertebrate nutrient selected from the group consisting of 24-methylene cholesterol, isofucosterol, cholesterol or desmosterol.
Provided is a method for feeding invertebrates or aquaculture organisms comprising: ? providing a non-pollen composition comprising a nutritionally effective amount of isofucosterol, fucosterol or a mixture thereof; and ? administering the non-pollen composition to invertebrates.
Provided are methods for feeding invertebrates comprising: providing a non-pollen composition comprising a nutritionally effective amount of proanthocyanidins; and administering the non-pollen composition to invertebrates.
A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
Provided is a method for feeding invertebrates, comprising ■ Providing a pollen substitute or supplement composition for invertebrates, in particular for honey bees and bumble bees out of yeast selected from the group consisting of S. cerevisiae, Xanthophyllomyces sp., S. japonicus or Yarrowia lipolytica, ■ Administering the composition to invertebrates, wherein the composition is essentially free of ergosterol or zymosterol or combinations thereof.
The present invention relates to compositions, methods and products for providing nutrition to insects such as bees, e.g., honey bees. Certain embodiments of the present invention also relate to methods of providing nutrition to bees e.g., colonies of bees together with methods of preparing a composition for providing nutrition to bees.
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