Example embodiments provide a control device and a biomedical illumination device enabling multiwavelength laser line generation with automated beam alignment. The control device may be configured to determine, based on monitored output beam pattern of the biomedical illumination device for illumination of a microscopic sample, a position of one or more beams of the output beam pattern in relation to a target position of the one or more beams within the output beam pattern; determine instructions for one or more actuator-controlled optics of the biomedical illumination device configured for beam steering to change a deflection angle of the actuator-controlled optics based on a difference between the determined position of the one or more beams of the output beam pattern and the target position of the one or more beams within the output beam pattern; and transmit the instructions to the one or more actuator-controlled optics.
G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
2.
MULTI-WAVELENGTH LASER BEAM PATTERN GENERATOR WITH AUTOMATED BEAM ALIGNMENT
Example embodiments provide a biomedical illumination device enabling multiwavelength laser line generation with automated beam alignment. The biomedical illumination device may include a plurality of laser light sources configured to provide beams of one or more wavelengths, wherein one or more of the beams are directed towards one or more actuator-controlled mirrors; the one or more actuator-controlled mirrors configured to steer the one or more beams for passing through a beam shaping element, wherein for each of the one or more beams at least one actuator-controlled mirror is configured for steering the respective beam automatically according to instructions received from a control device; the beam shaping element configured to output a beam pattern having a certain geometry for illumination of a microscopic sample based on the steered beams; and the control device configured to monitor the beams output from the beam shaping element to determine a position of the output beam pattern in relation to a target beam pattern position at the sample; determine instructions for one or more of the actuator-controlled mirrors to tilt in at least one axis based on a difference between the monitored position of the output beam pattern and the target beam pattern position at the microscopic sample; and transmit the instructions to the one or more actuator-controlled mirrors.
Example embodiments provide a biomedical illumination device (100) enabling multiwavelength laser line generation with automated beam alignment. The biomedical illumination device comprises a plurality of laser light sources (102) configured to provide beams of one or more wavelengths, wherein one or more of the beams are directed towards one or more actuator-controlled mirrors (104); the one or more actuator-controlled mirrors (104) configured to steer the one or more beams for passing through a beam shaping element (108), wherein for each of the one or more beams at least one actuator-controlled mirror (104) is configured for steering the respective beam automatically according to instructions received from a control device (110); the beam shaping element (108) configured to output a beam pattern having a certain geometry for illumination of a microscopic sample based on the steered beams; and the control device (110) configured to monitor the beams output from the beam shaping element (108) to determine a position of the output beam pattern in relation to a target beam pattern position at the sample; determine instructions for one or more of the actuator-controlled mirrors (104) to tilt in at least one axis based on a difference between the monitored position of the output beam pattern and the target beam pattern position at the microscopic sample; and transmit the instructions to the one or more actuator-controlled mirrors (104).
G01N 15/14 - Optical investigation techniques, e.g. flow cytometry
G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
G02B 27/09 - Beam shaping, e.g. changing the cross-sectioned area, not otherwise provided for
Disclosed is a method (100) for fabricating high-aspect-ratio gratings. The method comprises providing a semiconductor substrate (200). The method further comprises depositing a first layer (202) of a first silicon based material on the semiconductor substrate; depositing a second layer (204) of a second silicon-based material on the first layer; and depositing a third layer (206) of a resist material on the second layer. The method further comprises forming a pattern (208) in the third layer by exposing the resist material. The method further comprises transferring the pattern from the third layer into the second layer by etching; and transferring the pattern from the second layer into the first layer by etching, using the patterned second layer as a first mask layer. The method further comprises forming a grating (210) into the semiconductor substrate by etching, using the patterned first layer as a second mask layer.
Disclosed is a method for fabricating high-aspect-ratio gratings that includes providing a semiconductor substrate. The method further includes depositing a first layer of a first silicon-based material on the semiconductor substrate; depositing a second layer of a second silicon-based material on the first layer; and depositing a third layer of a resist material on the second layer. The method further includes forming a pattern in the third layer by exposing the resist material. The method further includes transferring the pattern from the third layer into the second layer by etching; and transferring the pattern from the second layer into the first layer by etching, using the patterned second layer as a first mask layer. The method further includes forming a grating into the semiconductor substrate by etching, using the patterned first layer as a second mask layer.
C23C 16/50 - Chemical coating by decomposition of gaseous compounds, without leaving reaction products of surface material in the coating, i.e. chemical vapour deposition [CVD] processes characterised by the method of coating using electric discharges
G02B 1/02 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements made of crystals, e.g. rock-salt, semiconductors
A method for fabricating a semiconductor device on a semiconductor substrate and an optical laser system utilizing laser devices fabricated from the method. The optical laser system includes a first laser device configured to generate laser light, an optical assembly configured to receive the generated laser light from the first laser device, and collimate the received laser light from the first laser device to provide collimated laser light. The optical laser system further comprises a second laser device configured to receive the collimated laser light, and amplify the received collimated laser light via application of a drive current to generate amplified laser light, wherein at least one of the first laser device and the second laser device is fabricated via the method for fabricating a semiconductor device on a semiconductor substrate.
Disclosed is a method for monitoring medical treatment of tissue. The method comprises: receiving fluorescence spectrum measured while tissue is illuminated by laser light emitted by biomedical laser device (204, 300); obtaining reference fluorescence data from digital library of fluorescence data, based on type of photosensitizer required to be present in tissue; determining region of interest in measured fluorescence spectrum, based on reference fluorescence spectrum in reference fluorescence data; determining whether signal to noise ratio of measured fluorescence spectrum in region of interest is greater than first threshold; when such determination is true, determining correlation coefficient indicative of correlation between region of interest and reference fluorescence spectrum; determining whether correlation coefficient is greater than second threshold; and when such determination is true, determining that photosensitizer is present in tissue.
Disclosed is a method for monitoring medical treatment of tissue. The method includes: receiving fluorescence spectrum measured while tissue is illuminated by laser light emitted by biomedical laser device; obtaining reference fluorescence data from digital library of fluorescence data, based on type of photosensitizer required to be present in tissue; determining region of interest in measured fluorescence spectrum, based on reference fluorescence spectrum in reference fluorescence data; determining whether signal to noise ratio of measured fluorescence spectrum in region of interest is greater than first threshold; when such determination is true, determining correlation coefficient indicative of correlation between region of interest and reference fluorescence spectrum; determining whether correlation coefficient is greater than second threshold; and when such determination is true, determining that photosensitizer is present in tissue.
Example embodiments enable adaptive light fractionation during a biomedical illumination process, such as phototherapeutic illumination. An apparatus is configured to obtain measurements of one or more physical parameters associated with a target while an illumination program is performed on the target; determine, based on the measurements, that a predefined limit for at least one of the physical parameters is met; determine a change in at least one light fractionation setting of the illumination program when the at least one predefined limit is met; and initiate at least one action to change the at least one light fractionation setting.
Example embodiments enable adaptive light fractionation during a biomedical illumination process, such as phototherapeutic illumination. An apparatus is configured to obtain measurements of one or more physical parameters associated with a target while an illumination program is performed on the target; determine, based on the measurements, that a predefined limit for at least one of the physical parameters is met; determine a change in at least one light fractionation setting of the illumination program when the at least one predefined limit is met; and initiate at least one action to change the at least one light fractionation setting.
A61N 5/067 - Radiation therapy using light using laser light
G16H 20/40 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
G16H 40/63 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for local operation
11.
Optical assembly and optical system for beam steering and homogenization
An optical assembly including light sources emitting light beams having multiple wavelengths; fiber combiner(s) arranged to combine light beams into combined beam, light beams enter fiber combiner(s); optical homogenizer(s), combined beam having non-homogenous intensity profile received at third end and combined beam having homogeneous intensity profile exits at fourth end; first optical element(s) second optical element(s), between optical homogenizer(s) and light guide(s), first optical element(s) and second optical(s) element collectively steer combined beam towards light guide(s), when optical assembly in use, second optical element(s) is adjustable to steer combined beam; first actuator(s) coupled to first optical element(s); controller coupled to first actuator(s), controller generate first signal controlling first actuator(s) that combined beam is steered by first optical element(s) also causing vibration of first optical element(s) at randomized pattern.
F21V 8/00 - Use of light guides, e.g. fibre optic devices, in lighting devices or systems
G02B 6/28 - Optical coupling means having data bus means, i.e. plural waveguides interconnected and providing an inherently bidirectional system by mixing and splitting signals
An optical assembly (100, 200) comprising light sources (102, 202a, 202b, 202c) emitting light beams having multiple wavelengths; fiber combiner(s) (104, 204) arranged to combine light beams into combined beam, light beams enter fiber combiner(s); optical homogenizer(s) (106, 206), combined beam having non-homogenous intensity profile received at third end (116a) and combined beam having homogeneous intensity profile exits at fourth end (116b); first optical element(s) (108, 208) second optical element(s) (110, 210), between optical homogenizer(s) and light guide(s) (118, 304, 406), first optical element(s) and second optical(s) element collectively steer combined beam towards light guide(s), when optical assembly in use, second optical element(s) is adjustable to steer combined beam; first actuator(s) (212) coupled to first optical element(s); controller (214) coupled to first actuator(s), controller generate first signal controlling first actuator(s) that combined beam is steered by first optical element(s) also causing vibration of first optical element(s) at randomized pattern.
G02B 26/08 - Optical devices or arrangements for the control of light using movable or deformable optical elements for controlling the direction of light
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceuticals, medical and veterinary preparations;
sanitary preparations for medical purposes. Scientific, research, navigation, surveying, photographic,
cinematographic, audiovisual, optical, weighing, measuring,
signalling, detecting, testing, inspecting, life-saving and
teaching apparatus and instruments; apparatus and
instruments for conducting, switching, transforming,
accumulating, regulating or controlling the distribution or
use of electricity; apparatus and instruments for recording,
transmitting, reproducing or processing sound, images or
data; recorded and downloadable media content; computer
software; blank digital or analogue recording and storage
media; computers and computer peripheral devices;
application software; downloadable computer software;
downloadable computer software applications; software and
applications for mobile devices; computer software relating
to the medical field; cloud computing software; graphical
user interface software; artificial intelligence and machine
learning software; artificial intelligence software for
healthcare; lasers; lasers, not for medical purposes; laser
equipment for non-medical purposes; lasers for scientific
and industrial use; laser diodes; laser sensors; laser
installations, other than for medical use; solid-state
lasers; optical apparatus and instruments; optical
transmitters; semi-conductors; optical semi-conductors;
parts and fittings for all the above-mentioned goods. Medical, surgical, dental and veterinary apparatus and
instruments; lasers for medical purposes; laser instruments
for medical purposes; lasers for use in surgery; lasers for
veterinary purposes; lasers for ophthalmic purposes; medical
instruments incorporating lasers; laser installations for
medical use; laser instruments capable of producing
pulsating laser beams [for medical use]; laser light
treatment instruments for medical use; laser beam delivery
instruments for medical use; instruments for the delivery of
laser radiation [for medical purposes]; instruments for the
application of laser radiation for dental purposes;
instruments for the application of laser radiation for
surgical purposes; lasers incorporating optical fibres for
medical use; ophthalmological instruments; therapeutic
instruments for ophthalmology; parts and fittings for all
the above-mentioned goods. Installation, servicing, repair and maintenance of lasers
and laser apparatus; installation, servicing, repair and
maintenance of medical machines, apparatus and instruments;
providing information relating to all the above-mentioned
services. Scientific and technological services and research and
design relating thereto; industrial analysis, industrial
research and industrial design services; quality control and
authentication services; design and development of computer
hardware and software; IT services; software as a service
[SaaS]; quantum computing services; cloud computing; cloud
service hosting; industrial analysis services; research
services; biomedical research services; calibration
[measuring]; calibration services relating to lasers and
laser instruments; calibration services relating to
electronic instruments; calibration services relating to
medical instruments; computer systems integration services;
providing information relating to all the above-mentioned
services. Medical services; veterinary services; hygienic and beauty
care for human beings or animals; medical and veterinary
analysis services; medical diagnostic services [testing and
analysis]; providing medical information; advisory services
relating to medical services; advisory services relating to
medical apparatus and instruments.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceuticals, medical and veterinary preparations for the treatment of eye diseases and conditions, cancer and for use in connection with DNA sequencing, genetic testing and medical imaging; sanitary preparations for medical purposes Apparatus and instruments for recording, transmitting, reproducing or processing sound, images or data; recorded and downloadable media content, namely, prerecorded CDs and downloadable audio and video recordings featuring information on the use, installation, repair and maintenance of lasers and laser apparatus; downloadable computer software for operating lasers for industrial or medical use; computers and computer peripheral devices; downloadable application software for operating industrial and medical lasers; downloadable computer software for use in recording industrial and medical laser data; downloadable computer software applications for operating laser installations; downloadable software and applications for mobile devices for medical and industrial imaging; recorded and downloadable computer software for ophthalmic and oncologic imaging, DNA sequencing and genetic testing relating to the medical field; downloadable cloud computing software for managing virtual machines on a cloud computing platform; downloadable graphical user interface software; downloadable artificial intelligence and machine learning software for hosting laser technologies; downloadable artificial intelligence software for healthcare, namely, for treating cancer, eye diseases and eye conditions; lasers for non-medical purposes; lasers, not for medical purposes; laser equipment for non-medical purposes; lasers for scientific and industrial use for non-medical purposes; laser diodes; laser pressure sensors; laser installations, other than for medical use; solid-state lasers, not for medical purposes; optical apparatus and instruments, namely, optical sensors, scanners and receivers; wireless optical transmitters; semi-conductors; optical semi-conductors; replacement and structural parts for all the above-mentioned goods Lasers for medical purposes; laser instruments for medical purposes; lasers for use in surgery; lasers for veterinary purposes; lasers for ophthalmic purposes; medical instruments incorporating lasers for use in surgery; laser installations for medical use; laser instruments capable of producing pulsating laser beams for medical use; laser light treatment instruments for medical use; laser beam delivery instruments for medical use; instruments for the delivery of laser radiation for medical purposes; instruments for the application of laser radiation for dental purposes; instruments for the application of laser radiation for surgical purposes; lasers incorporating optical fibres for medical use; ophthalmological instruments, namely, laser-based devices for therapeutic treatment of retinal and other ocular diseases; therapeutic instruments for ophthalmology, namely, laser-based instruments for photodynamic therapy, thermal therapy, and immunotherapy in ophthalmic applications; replacement and structural parts for all the above-mentioned goods Installation, repair and maintenance of lasers and laser apparatus; installation, repair and maintenance of medical machines, apparatus and instruments; providing information relating to all the abovementioned services Scientific and technological services and research and design relating thereto, namely, scientific research in the field of medical and industrial imaging and design of medical and industrial imaging equipment; industrial computer systems analysis, industrial medical research and industrial design services; quality control for others and authentication of data in the field of medical records using blockchain technology; design and development of computer hardware and software; IT integration services; software as a service (SaaS) featuring software for operating lasers for medical and industrial use; consulting in the field of quantum computing; cloud computing featuring software for use in recording medical and industrial laser data; cloud service hosting provider services; industrial analysis services, namely, product failure analysis services; medical research services; biomedical research services; calibration; calibration services relating to lasers and laser instruments; calibration services relating to electronic instruments; calibration services relating to medical instruments; computer systems integration services; providing information relating to all the above-mentioned services Medical services; veterinary services; hygienic and beauty care for human beings and animals; medical and veterinary analysis services for the diagnosis and treatment of persons and animals; testing and analysis services being medical diagnostic services; providing medical information; advisory services relating to medical services; technical medical advisory services relating to medical apparatus and instruments
15.
AN APPARATUS AND A METHOD FOR FLUORESCENCE IMAGING
According to an example embodiment, a hyperspectral detection approach is used in combination with narrow linewidth illumination for fluorescence excitation. A more efficient fluorophores excitation and image capturing may be provided, and thus high-quality data for subsequent hyperspectral analysis may be obtained. An apparatus, a method, a system and a computer program are disclosed.
Disclosed is an apparatus and method for fluorescence excitation and detection. The apparatus comprises one or more light sources for providing excitation light for fluorescence excitation at an observation spot along an optical axis for excitation, an optical collection element for collecting fluorescence light generated by the excitation light at two or more different observation spots into two or more different measurement channels with an optical axis for collecting non-parallel to the optical axis for excitation of each of the one or more light sources, and, for each of the two or more measurement channels and thereby for each of the two or more observation spots, a dedicated optical detector for detecting fluorescence from the fluorescence light collected by the optical collection element.
Disclosed is an apparatus and method for fluorescence excitation and detection. The apparatus comprises one or more light sources for providing excitation light for fluorescence excitation at an observation spot along an optical axis for excitation, an optical collection element for collecting fluorescence light generated by the excitation light at two or more different observation spots into two or more different measurement channels with an optical axis for collecting non-parallel to the optical axis for excitation of each of the one or more light sources, and, for each of the two or more measurement channels and thereby for each of the two or more observation spots, a dedicated optical detector for detecting fluorescence from the fluorescence light collected by the optical collection element.
A hyperspectral detection approach is used in combination with narrow linewidth illumination for fluorescence excitation. A more efficient fluorophores excitation and image capturing may be provided, and thus high-quality data for subsequent hyperspectral analysis may be obtained. An apparatus, a method, a system and a computer program are disclosed.
Disclosed is a method (100) for fabricating a semiconductor device on a semiconductor substrate (202), wherein the semiconductor device is adapted to provide target lasing properties, the method comprises creating (102), a mask layer (204) over the semiconductor substrate (202), the mask layer (204) having at least one opening to expose a region of the semiconductor substrate (202), etching (104) using a first etching process the exposed region (208), utilizing inductively coupled plasma with preselected first set of parameters to obtain a baseline mesa profile (210), the baseline mesa profile having a baseline mesa angle, re-etching (106) using a second etching process the etched region, utilizing inductively coupled plasma with preselected second set of parameters, to alter the baseline mesa profile (210) to obtain a requisite mesa profile (220) having a requisite mesa angle defined by the target lasing properties and the requisite mesa angle being different from the baseline mesa angle, removing (108) the mask layer (204) and defining (110) a p-n junction (226) for the semiconductor substrate (202).
A method for fabricating a semiconductor device on a semiconductor substrate, wherein the semiconductor device is adapted to provide target lasing properties, the method includes creating, a mask layer over the semiconductor substrate, the mask layer having at least one opening to expose a region of the semiconductor substrate, etching using a first etching process the exposed region, utilizing inductively coupled plasma with preselected first set of parameters to obtain a baseline mesa profile, the baseline mesa profile having a baseline mesa angle, re-etching using a second etching process the etched region, utilizing inductively coupled plasma with preselected second set of parameters, to alter the baseline mesa profile to obtain a requisite mesa profile having a requisite mesa angle defined by the target lasing properties and the requisite mesa angle being different from the baseline mesa angle, removing the mask layer and defining a p-n junction for the semiconductor substrate.
An apparatus for stacking and coating of very short cavity laser diode arrays. The apparatus includes an array holder fixture to securely hold the very short cavity laser diode arrays and spacer arrays, and a stacking plate. The array holder fixture including a top-side presser to secure a stack of very short cavity laser arrays and spacer arrays from a first end of the stack, a bottom-side presser to secure the stack of very short cavity laser arrays and spacer arrays from a second end of the stack, and a pair of side clamps. The array holder fixture is operatively coupled to the stacking plate during the stacking of the very short cavity laser diode arrays and spacer arrays.
Disclosed is an apparatus (100, 300, 400, 700, 500) for stacking and coating of very short cavity laser diode arrays (502, 602). The apparatus comprises an array holder fixture (102, 304, 406, 506, 702) to securely hold the very short cavity laser diode arrays (502, 602) and spacer arrays 5 (604), and a stacking plate (202, 302, 402, 704). The array holder fixture comprising a top-side presser (104, 706) to secure a stack of very short cavity laser arrays and spacer arrays from a first end of the stack, a bottom-side presser (106, 708) to secure the stack of very short cavity laser arrays and spacer arrays from a second end of the stack, and a pair 10 of side clamps (404A, 404B, 508A, 508B, 710A, 710B). The array holder fixture is operatively coupled to the stacking plate during the stacking of the very short cavity laser diode arrays and spacer arrays.
H01S 5/02365 - Fixing laser chips on mounts by clamping
H01L 21/67 - Apparatus specially adapted for handling semiconductor or electric solid state devices during manufacture or treatment thereofApparatus specially adapted for handling wafers during manufacture or treatment of semiconductor or electric solid state devices or components
H01S 5/40 - Arrangement of two or more semiconductor lasers, not provided for in groups
23.
Methods for passivating sidewalls of semiconductor wafers and semiconductor devices incorporating semiconductor wafers
A method for passivating sidewalls of patterned semiconductor wafer including ridge(s). The method includes: depositing first layer of first dielectric material on pattern surface of said wafer; etching portion of first layer to obtain tapered portions of first dielectric material along sidewall(s) of ridge(s); depositing second layer of second dielectric material on tapered portions and said wafer; depositing photo-sensitive material on second layer; aligning mask with photo-sensitive material, wherein portion(s) of photo-sensitive material corresponding to top surface of ridge(s) is/are unmasked, and remaining portion is masked; applying developing solution and exposing photo-sensitive material to remove portion(s) of photo-sensitive material; etching portion(s) of second layer that is/are deposited on top surface of ridge(s); and removing photo-sensitive material.
Disclosed is a method for passivating sidewalls of patterned semiconductor wafer (200, 318, 402) comprising ridge(s) (202, 204, 320,410). The method comprises: depositing first layer (206) of first dielectric material on pattern surface of said wafer; etching portion of first layer to obtain tapered portions (208, 210, 212, 214, 322, 324) of first dielectric material along sidewall(s) (216, 218, 220, 222, 314, 316) of ridge(s); depositing second layer (224, 326) of second dielectric material on tapered portions and said wafer; depositing photo-sensitive material (226) on second layer; aligning mask (228) with photo-sensitive material, wherein portion(s) (230, 232) of photo-sensitive material corresponding to top surface (234, 236, 418) of ridge(s) is/are unmasked, and remaining portion is masked; applying developing solution and exposing photo-sensitive material to remove portion(s) of photo-sensitive material; etching portion(s) (238, 240) of second layer that is/are deposited on top surface of ridge(s); and removing photo-sensitive material.
H01L 21/786 - Manufacture or treatment of devices consisting of a plurality of solid state components or integrated circuits formed in, or on, a common substrate with subsequent division of the substrate into plural individual devices to produce devices, each consisting of a single circuit element the substrate being other than a semiconductor body, e.g. insulating body
25.
Method for light-activated drug delivery and system
A method and a system for light-activated drug delivery. An optical probe is coupled to a tissue for transmitting light signals to the tissue for actuating and/or monitoring drug delivery with a multi-phase method for drug delivery. A first light signal is transmitted through the optical probe for actuating and/or monitoring the drug delivery and a second light signal having a different wavelength is transmitted, simultaneously with the first light signal, through the optical probe for actuating and/or monitoring the drug delivery.
A theranostic laser system for light-activated drug delivery and monitoring. The system includes a light source, a light receiver and a coupler for simultaneously coupling a first optical delivery fiber to the light source for transmitting one or more first downstream light signals from the light source to the first optical delivery fiber and to the light receiver for transmitting one or more first upstream light signals from the first optical delivery fiber to the light receiver.
Disclosed is a theranostic laser system for light-activated drug delivery and monitoring. The system comprises a light source, a light receiver and a coupler for simultaneously coupling a first optical delivery fiber to the light source for transmitting one or more first downstream light signals from the light source to the first optical delivery fiber and to the light receiver for transmitting one or more first upstream light signals from the first optical delivery fiber to the light receiver.
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
28.
METHOD FOR LIGHT-ACTIVATED DRUG DELIVERY AND SYSTEM
Disclosed is a method and a system for light-activated drug delivery. An optical probe is coupled to a tissue for transmitting light signals to the tissue for actuating and/or monitoring drug delivery with a multi-phase method for drug delivery. A first light signal is transmitted through the optical probe for actuating and/or monitoring the drug delivery and a second light signal having a different wavelength is transmitted, simultaneously with the first light signal, through the optical probe for actuating and/or monitoring the drug delivery.
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor
29.
Monitoring assistance and control of a theranostic medical laser system by voice
Various example embodiments relate to guiding a user of a medical laser device by voice based on monitored treatment data. In addition, a voice control procedure for operating the medical laser device with improved safety is provided. Improved usage of the medical laser device is enabled also in situations where there is a limited visual and physical access to control the device. An apparatus, a method, a theranostic system and a computer program are disclosed.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 18/20 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
G10L 15/22 - Procedures used during a speech recognition process, e.g. man-machine dialog
A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
30.
MONITORING ASSISTANCE AND CONTROL OF A THERANOSTIC MEDICAL LASER SYSTEM BY VOICE
Various example embodiments relate to guiding a user of a medical laser device by voice based on monitored treatment data. In addition, a voice control procedure for operating the medical laser device with improved safety is provided. Improved usage of the medical laser device is enabled also in situations where there is a limited visual and physical access to control the de vice. An apparatus, a method, a theranostic system and a computer program are disclosed.
A61B 18/22 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser the beam being directed along or through a flexible conduit, e.g. an optical fibreHand-pieces therefor
31.
GUIDING ADJUSTMENTS OF A LASER SPOT SIZE DURING OPHTHALMIC LASER THERAPY TREATMENT
Various example embodiments relate to guiding a user of an ophthalmic laser therapy treatment device based on non-speech sounds in response to changes of a monitored laser spot size. A device may be configured to calculate a required parameter change of the current laser spot size to achieve a required laser spot size. The device may further determine characteristics for the non-speech sounds indicative of the required change for the user. Hence, quick and intuitively provided user inputs may be enabled to set the required laser spot size during treatment. A device, a method, a system and a computer program are disclosed.
Disclosed is a method for forming a contact surface (202) on a top (208) of a mesa structure (204) formed on a semiconductor substrate (206) deposited with an insulating layer (212). The method comprises depositing a first resist layer (214) over the insulating layer, depositing a second resist layer (216) over the first resist layer, defining a first portion (215) of the second resist layer, wherein the first portion overlaps the top of the mesa structure, forming a first opening (218) in the first portion by treating the second resist layer to expose a second portion (219) of the first resist layer beneath thereof, forming a second opening (220) in the first resist layer, by treating the exposed second portion to expose a third portion (221) of the insulating layer beneath thereof, and etching the exposed third portion to form the contact surface on the top of the mesa structure.
A method for forming a contact surface on a top of a mesa structure formed on a semiconductor substrate deposited with an insulating layer. The method includes depositing a first resist layer over the insulating layer, depositing a second resist layer over the first resist layer, defining a first portion of the second resist layer, wherein the first portion overlaps the top of the mesa structure, forming a first opening in the first portion by treating the second resist layer to expose a second portion of the first resist layer beneath thereof, forming a second opening in the first resist layer, by treating the exposed second portion to expose a third portion of the insulating layer beneath thereof, and etching the exposed third portion to form the contact surface on the top of the mesa structure.
A method for re-configuring a biomedical laser device. The biomedical laser device is pre-configured to be operable in one or more operational modes, and is provided with set of operational parameters that are employed for at least one of: given medical procedure, given medical treatment, activation of given drug, illumination of given dye. The method includes collecting information indicative of light output properties of biomedical laser device measured during given operational mode; detecting deviation in measured light output properties with respect to predefined light output properties for given operational mode; determining new set of operational parameters that are to be employed for at least one of: new medical procedure, new medical treatment, activation of new drug, illumination of new dye; and sending new set of operational parameters to biomedical laser device for re-configuring biomedical laser device to be operable in a new operational mode.
A61B 18/20 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A method for operating a biomedical laser. The method includes providing the biomedical laser having a first range of operational parameters; providing a second range of operational parameters for the biomedical laser; activating the biomedical laser to operate within the second range of operational parameters; identifying a need for a change in operational parameters of the biomedical laser; and triggering an action based on the identified need. The action includes providing a third range of operational parameters for the biomedical laser and activating the biomedical laser to operate within the third range of operational parameters; and de-activating a range of operational parameters. The second and third range of operational parameters is within the first range of operational parameters.
A61B 18/20 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
