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Found results for
 patents
1.
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PYRAZINE DERIVATIVES FOR THE TREATMENT OF SKIN DISORDERS
| Application Number |
EP2024088049 |
| Publication Number |
2025/133218 |
| Status |
In Force |
| Filing Date |
2024-12-20 |
| Publication Date |
2025-06-26 |
| Owner |
PHAMRI NORDEN AB (Sweden)
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| Inventor |
- Winge, Mårten
- Szafran, Rebecca
- Malmström, Jonas
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Abstract
The application relates to the compounds 3,5-Diamino-6-chloro-N- [N-[2-[2-(trifluoromethyl)phenyl]ethyl]carbamimidoyl]pyrazine-2- carboxamide (Formula I), 3,5-Diamino-N-[N-(lH-benzimidazol-2-yl) carbamimidoyl]-6-chloropyrazine-2-carboxamide (Formula II) and 3,5- Diamino-6-chloro-N-[N-(2-cyclopentylethyl)carbamimidoyl]pyrazine-2- carboxamide (Formula III), the medical use thereof and in particular use in treatment of a skin disorder. Additionally, related pharmaceutical and cosmetic compositions are disclosed.
IPC Classes ?
- C07D 241/32 - (Amino-pyrazinoyl) guanidines
- C07D 403/12 - Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group containing two hetero rings linked by a chain containing hetero atoms as chain links
- C07C 53/10 - Salts thereof
- C07C 53/18 - Halogenated acetic acids containing fluorine
- C07C 59/08 - Lactic acid
- A61P 17/06 - Antipsoriatics
- A61P 17/00 - Drugs for dermatological disorders
- A61P 17/10 - Anti-acne agents
- A61K 31/4965 - Non-condensed pyrazines
- A61K 31/497 - Non-condensed pyrazines containing further heterocyclic rings
- A61Q 19/00 - Preparations for care of the skin
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2.
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METHOD OF TREATING A SKIN DISORDER
| Application Number |
18274078 |
| Status |
Pending |
| Filing Date |
2022-01-25 |
| First Publication Date |
2025-01-09 |
| Owner |
PHAMRI Norden AB (Sweden)
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| Inventor |
- Szafran, Rebecca
- Winge, Mårten
- Batljan, Ilija
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Abstract
The present invention relates to a method of treating a skin disorder in a subject in need thereof by administering to the human an effective dose of a compound represented by formula (I)
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3.
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AMILORIDE DERIVATIVES FOR TREATING INFLAMMATION IN THE INTESTINES
| Application Number |
EP2022078899 |
| Publication Number |
2023/066893 |
| Status |
In Force |
| Filing Date |
2022-10-18 |
| Publication Date |
2023-04-27 |
| Owner |
PHAMRI NORDEN AB (Sweden)
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| Inventor |
- Szafran, Rebecca
- Winge, Mårten
- Batljan, Ilija
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Abstract
The present invention relates to a method of treating a medical condition involving an inflammation in the intestines in a subject by administering to a subject in need thereof an effective dose of a compound represented by formula (I) or a pharmaceutically acceptable salt thereof.
IPC Classes ?
- A61K 31/4965 - Non-condensed pyrazines
- A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
- A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
- A61K 9/00 - Medicinal preparations characterised by special physical form
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4.
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METHOD OF TREATING A SKIN DISORDER
| Document Number |
03209427 |
| Status |
Pending |
| Filing Date |
2022-01-25 |
| Open to Public Date |
2022-07-28 |
| Owner |
PHAMRI NORDEN AB (Sweden)
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| Inventor |
- Szafran, Rebecca
- Winge, Marten
- Batljan, Ilija
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Abstract
The present invention relates to a method of treating a skin disorder in a subject in need thereof by administering to the human an effective dose of a compound represented by formula (I)
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5.
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METHOD OF TREATING A SKIN DISORDER BY ADMINISTERING AN AMILORIDE DERIVATIVE
| Application Number |
SE2022050071 |
| Publication Number |
2022/159028 |
| Status |
In Force |
| Filing Date |
2022-01-25 |
| Publication Date |
2022-07-28 |
| Owner |
PHAMRI NORDEN AB (Sweden)
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| Inventor |
- Szafran, Rebecca
- Winge, Mårten
- Batljan, Ilija
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Abstract
The present invention relates to a method of treating a skin disorder in a subject in need thereof by administering to the human an effective dose of a compound represented by formula (I)
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