BWXT Medical Ltd.

Canada

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Date
2025 (YTD) 1
2024 4
2023 3
2021 2
IPC Class
G01T 1/36 - Measuring spectral distribution of X-rays or of nuclear radiation 4
G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes 4
B01D 59/04 - Separation by phase transition by distillation 2
B01D 59/26 - Separation by extracting by sorption, i.e. absorption, adsorption, persorption 2
B01F 21/00 - Dissolving 2
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Status
Pending 7
Registered / In Force 3
Found results for  patents

1.

SYSTEM AND METHOD FOR GERMANIUM-68 ISOTOPE PRODUCTION

      
Document Number 03251398
Status Pending
Filing Date 2021-01-15
Open to Public Date 2025-02-28
Owner BWXT Medical Ltd. (Canada)
Inventor
  • Wong, Chung Kay Michael
  • Whyte, Raymond Jeffery

Abstract

A system and method for producing Germanium-68 (Ge-68) isotopes is provided. The method includes irradiating a plated or encapsulated target containing Gallium, dissolving the irradiated target with an acid, and purifying the dissolved target by distillation to produce purified Ge-68. A dissolution cell assembly is provided for use in the dissolution step of the method.

IPC Classes  ?

  • B01D 3/00 - Distillation or related exchange processes in which liquids are contacted with gaseous media, e.g. stripping
  • B01D 59/04 - Separation by phase transition by distillation
  • B01F 21/00 - Dissolving

2.

METHOD FOR PRODUCTION OF ACTINIUM-225

      
Application Number 18397136
Status Pending
Filing Date 2023-12-27
First Publication Date 2024-07-04
Owner BWXT Medical Ltd. (Canada)
Inventor
  • Causey, Patrick
  • Tamboline, Blake
  • Wong, Michael
  • Lee, Alexander K.

Abstract

A method for producing Actinium-225 from proton spallation of thorium targets via a radium generator. The method includes dissolving a thorium target into a thorium solution, evaporating the thorium solution thereby resulting in a dried thorium salt, reconstituting the dried thorium salt in sulfuric acid for formation of neutral thorium species, passing neutral thorium species through a cation exchange chromatography column for bulk thorium removal, conducting extraction chromatography in a mixed resin bed thereby eluting radium, evaporating the radium containing eluent, reconstituting dried radium, and conducting extraction chromatography to elute a purified radium fraction thereby constructing a radium generator.

IPC Classes  ?

  • G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes

3.

METHOD FOR PRODUCTION OF ACTINIUM-225

      
Application Number IB2023000800
Publication Number 2024/141793
Status In Force
Filing Date 2023-12-28
Publication Date 2024-07-04
Owner BWXT MEDICAL LTD. (Canada)
Inventor
  • Causey, Patrick
  • Tamboline, Blake
  • Wong, Michael
  • Lee, Alexander, K.

Abstract

A method for producing Actinium-225 from proton spallation of thorium targets via a radium generator. The method includes dissolving a thorium target into a thorium solution, evaporating the thorium solution thereby resulting in a dried thorium salt, reconstituting the dried thorium salt in sulfuric acid for formation of neutral thorium species, passing neutral thorium species through a cation exchange chromatography column for bulk thorium removal, conducting extraction chromatography in a mixed resin bed thereby eluting radium, evaporating the radium containing eluent, reconstituting dried radium, and conducting extraction chromatography to elute a purified radium fraction thereby constructing a radium generator.

IPC Classes  ?

  • G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes

4.

METHOD FOR DETERMINATION OF ACTINIUM-227 IN ACTINIUM-225

      
Application Number 18397165
Status Pending
Filing Date 2023-12-27
First Publication Date 2024-07-04
Owner BWXT Medical Ltd. (Canada)
Inventor Oelsner, Stephen M.

Abstract

A method for determination of Actinium-227 (Ac-227) via indirectly produced Ra-225/Ac-225 parent/daughter. The determination of Ac-227 or its decay daughters can be used as a “pre-release” quality control test for total Ac-227 content.

IPC Classes  ?

  • G01T 1/36 - Measuring spectral distribution of X-rays or of nuclear radiation

5.

METHOD FOR DETERMINATION OF ACTINIUM-227 IN ACTINIUM-225

      
Application Number IB2023000799
Publication Number 2024/141792
Status In Force
Filing Date 2023-12-28
Publication Date 2024-07-04
Owner BWXT MEDICAL LTD. (Canada)
Inventor Oelsner, Stephen, M.

Abstract

A method for determination of Actinium-227 (Ac-227 ) via indirectly produced Ra- 225/Ac-225 parent/daughter. The determination of Ac-227 or its decay daughters can be used as a "pre-release" quality control test for total Ac-227 content. Method includes : Extracting actinium isotopes from purified Ra-225 to generate Stock A. Resting Stock A to allow Ac-227 to decay to Th-227. Adding a Thorium tracer to Stock A. Chemically isolating the Th-227 and Thorium tracer. Mounting the thorium isotopes to an alpha counting disc. Counting the alpha disc using alpha spectroscopy counting equipment to determined Th-227 quantity and tracer recovery percentage. Determine an amount of Ac-227 by using the counts.

IPC Classes  ?

  • G01T 1/167 - Measuring radioactive content of objects, e.g. contamination
  • G01T 1/36 - Measuring spectral distribution of X-rays or of nuclear radiation

6.

LU-177 RADIOCHEMISTRY SYSTEM AND METHOD

      
Document Number 03233550
Status Pending
Filing Date 2022-10-05
Open to Public Date 2023-04-13
Owner BWXT MEDICAL LTD. (Canada)
Inventor
  • Oelsner, Stephen M.
  • Hunter, Gary
  • Wiggins, Bryan Blake
  • Policke, Timothy A.
  • Glenn, David J.

Abstract

A method of making Lu- 177 involving dissolving enriched Yb2O3, loading dissolved enriched Yb2O3 on a first guard column containing resin prepared from (2-ethyl-1- hexyl)phosphonic acid mono(2-ethyl-1-hexyl)ester (HEH[EHP]), passing a first separation of a stream exiting from first guard column through a first resin cartridge containing dipentyl pentylphosphonate, collecting Lu- 177 onto a first collection column having resin containing tetraoctyl diglycolamide (DGA), loading an exiting stream from first collection column on a second guard column containing resin prepared from (2- ethyl-1-hexyl)phosphonic acid mono(2-ethyl-1-hexyl)ester (HEH[EHP]); passing a first separation of a stream exiting from second guard column through a second resin cartridge containing dipentyl pentylphosphonate; collecting Lu-177 onto a second collection column having resin containing DGA; passing a second separation of a stream exiting from second guard column through a third resin cartridge containing dipentyl pentylphosphonate; and collecting Lu-177 having passed through the third resin cartridge onto a third collection column having resin containing DGA.

IPC Classes  ?

  • B01D 59/26 - Separation by extracting by sorption, i.e. absorption, adsorption, persorption
  • G01T 1/36 - Measuring spectral distribution of X-rays or of nuclear radiation
  • G21G 1/06 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by neutron irradiation

7.

Lu-177 RADIOCHEMISTRY SYSTEM AND METHOD

      
Application Number 17959752
Status Pending
Filing Date 2022-10-04
First Publication Date 2023-04-13
Owner BWXT Medical Ltd. (Canada)
Inventor
  • Oelsner, Stephen M.
  • Hunter, Gary
  • Wiggins, Bryan Blake
  • Policke, Timothy A.
  • Glenn, David J.

Abstract

A method of making Lu-177 involving dissolving enriched Yb2O3, loading dissolved enriched Yb2O3 on a first guard column containing resin prepared from (2-ethyl-1-hexyl)phosphonic acid mono(2-ethyl-1-hexyl)ester (HEH[EHP]), passing a first separation of a stream exiting from first guard column through a first resin cartridge containing dipentyl pentylphosphonate, collecting Lu-177 onto a first collection column having resin containing tetraoctyl diglycolamide (DGA), loading an exiting stream from first collection column on a second guard column containing resin prepared from (2-ethyl-1-hexyl)phosphonic acid mono(2-ethyl-1-hexyl)ester (HEH[EHP]); passing a first separation of a stream exiting from second guard column through a second resin cartridge containing dipentyl pentylphosphonate; collecting Lu-177 onto a second collection column having resin containing DGA; passing a second separation of a stream exiting from second guard column through a third resin cartridge containing dipentyl pentylphosphonate; and collecting Lu-177 having passed through the third resin cartridge onto a third collection column having resin containing DGA.

IPC Classes  ?

  • G01N 30/60 - Construction of the column
  • G21G 4/08 - Radioactive sources other than neutron sources characterised by constructional features specially adapted for medical applications
  • A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation

8.

LU-177 RADIOCHEMISTRY SYSTEM AND METHOD

      
Application Number IB2022000574
Publication Number 2023/057816
Status In Force
Filing Date 2022-10-05
Publication Date 2023-04-13
Owner BWXT MEDICAL LTD. (Canada)
Inventor
  • Oelsner, Stephen, M.
  • Hunter, Gary
  • Wiggins, Bryan, Blake
  • Policke, Timothy, A.
  • Glenn, David, J.

Abstract

23233 on a first guard column containing resin prepared from (2-ethyl-1- hexyl)phosphonic acid mono(2-ethyl-1-hexyl)ester (HEH[EHP]), passing a first separation of a stream exiting from first guard column through a first resin cartridge containing dipentyl pentylphosphonate, collecting Lu- 177 onto a first collection column having resin containing tetraoctyl diglycolamide (DGA), loading an exiting stream from first collection column on a second guard column containing resin prepared from (2- ethyl-1-hexyl)phosphonic acid mono(2-ethyl-1-hexyl)ester (HEH[EHP]); passing a first separation of a stream exiting from second guard column through a second resin cartridge containing dipentyl pentylphosphonate; collecting Lu-177 onto a second collection column having resin containing DGA; passing a second separation of a stream exiting from second guard column through a third resin cartridge containing dipentyl pentylphosphonate; and collecting Lu-177 having passed through the third resin cartridge onto a third collection column having resin containing DGA.

IPC Classes  ?

  • B01D 59/26 - Separation by extracting by sorption, i.e. absorption, adsorption, persorption
  • G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
  • G01T 1/36 - Measuring spectral distribution of X-rays or of nuclear radiation
  • G21G 1/06 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by neutron irradiation

9.

SYSTEM AND METHOD FOR GERMANIUM-68 ISOTOPE PRODUCTION

      
Document Number 03165071
Status Pending
Filing Date 2021-01-15
Open to Public Date 2021-07-22
Owner BWXT MEDICAL LTD. (Canada)
Inventor
  • Wong, Chung Kay Michael
  • Whyte, Raymond Jeffery

Abstract

A system and method for producing Germanium-68 (Ge-68) isotopes is provided. The method includes irradiating a plated or encapsulated target containing Gallium, dissolving the irradiated target with an acid, and purifying the dissolved target by distillation to produce purified Ge-68. A dissolution cell assembly is provided for use in the dissolution step of the method.

IPC Classes  ?

  • B01D 59/04 - Separation by phase transition by distillation
  • B01F 21/00 - Dissolving
  • G21G 1/04 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators

10.

SYSTEM AND METHOD FOR GERMANIUM-68 ISOTOPE PRODUCTION

      
Application Number 17148880
Status Pending
Filing Date 2021-01-14
First Publication Date 2021-07-22
Owner BWXT MEDICAL LTD. (Canada)
Inventor
  • Wong, Chung Kay Michael
  • Whyte, Raymond Jeffery

Abstract

A system and method for producing Germanium-68 (Ge-68) isotopes is provided. The method includes irradiating a plated or encapsulated target containing Gallium, dissolving the irradiated target with an acid, and purifying the dissolved target by distillation to produce purified Ge-68. A dissolution cell assembly is provided for use in the dissolution step of the method.

IPC Classes  ?

  • G21G 1/00 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes
  • G21G 1/10 - Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation, or particle bombardment, e.g. producing radioactive isotopes outside of nuclear reactors or particle accelerators by bombardment with electrically-charged particles
  • B01D 5/00 - Condensation of vapoursRecovering volatile solvents by condensation