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Found results for
 patents
1.
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Preparation of flagellin vaccine adjuvant-based vaccine to induce production of antibody recognizing conformation of antigens, and application thereof
| Application Number |
17116104 |
| Grant Number |
11771753 |
| Status |
In Force |
| Filing Date |
2020-12-09 |
| First Publication Date |
2021-04-08 |
| Grant Date |
2023-10-03 |
| Owner |
- RHEE, JOON HAENG (Republic of Korea)
- LEE, SHEE EUN (Republic of Korea)
- JEONG, KWANG JOON (Republic of Korea)
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| Inventor |
- Rhee, Joon Haeng
- Lee, Shee Eun
- Jeong, Kwangjoon
- Park, Sang Chul
- Tan, Wenzhi
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Abstract
The present invention provides a vaccine composition for use in neurodegenerative diseases and an infectious virus vaccine composition for inducing an antibody recognizing the conformation of antigens. The vaccine composition of the present invention induces the production of an antibody recognizing the conformation of antigens. The antibody recognizing the conformation of antigens has high specificity for an antigen, and thus can be useful for ameliorating, preventing or treating diseases.
IPC Classes ?
- A61K 39/02 - Bacterial antigens
- C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
- A61K 39/00 - Medicinal preparations containing antigens or antibodies
- A61K 35/68 - Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
- A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A61K 9/00 - Medicinal preparations characterised by special physical form
- A61K 39/12 - Viral antigens
- A61P 31/18 - Antivirals for RNA viruses for HIV
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2.
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Preparation of flagellin vaccine adjuvant-based vaccine to induce production of antibody recognizing conformation of antigens, and application thereof
| Application Number |
16312510 |
| Grant Number |
10953082 |
| Status |
In Force |
| Filing Date |
2016-11-17 |
| First Publication Date |
2019-05-30 |
| Grant Date |
2021-03-23 |
| Owner |
- RHEE, JOON HAENG (Republic of Korea)
- LEE, SHEE EUN (Republic of Korea)
- JEONG, KWANG JOON (Republic of Korea)
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| Inventor |
- Rhee, Joon Haeng
- Lee, Shee Eun
- Jeong, Kwangjoon
- Park, Sang Chul
- Tan, Wenzhi
|
Abstract
The present invention provides a vaccine composition for use in neurodegenerative diseases and an infectious virus vaccine composition for inducing an antibody recognizing the conformation of antigens. The vaccine composition of the present invention induces the production of an antibody recognizing the conformation of antigens. The antibody recognizing the conformation of antigens has high specificity for an antigen, and thus can be useful for ameliorating, preventing or treating diseases.
IPC Classes ?
- A61K 39/02 - Bacterial antigens
- C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
- A61K 39/00 - Medicinal preparations containing antigens or antibodies
- A61K 39/12 - Viral antigens
- A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A61K 9/00 - Medicinal preparations characterised by special physical form
- A61P 31/18 - Antivirals for RNA viruses for HIV
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3.
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Modified flagellin improved toll-like receptor 5 stimulating activity
| Application Number |
13333857 |
| Grant Number |
08337865 |
| Status |
In Force |
| Filing Date |
2011-12-21 |
| First Publication Date |
2012-08-09 |
| Grant Date |
2012-12-25 |
| Owner |
- RHEE, JOON HAENG (Republic of Korea)
- LEE, SHEE EUN (Republic of Korea)
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| Inventor |
- Rhee, Joon Haeng
- Lee, Shee Eun
- Kim, Soo Young
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Abstract
Disclosed herein are flagellin mutants having an enhanced activity of stimulating the toll-like receptor-5 (hereinafter referred to as “TLR5”). More specifically, disclosed are flagellin mutants, prepared by point-mutating some of the amino acids of a TRL5 agonist flagellin so as to enhance the TRL-stimulating activity of the flagellin.
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4.
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Modified flagellin improved toll-like receptor 5 stimulating activity
| Application Number |
13333709 |
| Grant Number |
08337864 |
| Status |
In Force |
| Filing Date |
2011-12-21 |
| First Publication Date |
2012-08-09 |
| Grant Date |
2012-12-25 |
| Owner |
- RHEE, JOON HAENG (Republic of Korea)
- LEE, SHEE EUN (Republic of Korea)
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| Inventor |
- Rhee, Joon Haeng
- Lee, Shee Eun
- Kim, Soo Young
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Abstract
Disclosed herein are flagellin mutants having an enhanced activity of stimulating the toll-like receptor-5 (hereinafter referred to as “TLR5”). More specifically, disclosed are flagellin mutants, prepared by point-mutating some of the amino acids of a TRL5 agonist flagellin so as to enhance the TRL-stimulating activity of the flagellin.
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5.
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Modified flagellin improved toll-like receptor 5 stimulating activity
| Application Number |
12526187 |
| Grant Number |
08236327 |
| Status |
In Force |
| Filing Date |
2008-02-05 |
| First Publication Date |
2011-01-13 |
| Grant Date |
2012-08-07 |
| Owner |
- RHEE, JOON HAENG (Republic of Korea)
- LEE, SHEE EUN (Republic of Korea)
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| Inventor |
- Rhee, Joon Haeng
- Lee, Shee Eun
- Kim, Soo Young
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Abstract
Disclosed herein are flagellin mutants having an enhanced activity of stimulating the toll-like receptor-5 (hereinafter referred to as “TLR5”). More specifically, disclosed are flagellin mutants, prepared by point-mutating some of the amino acids of a TRL5 agonist flagellin so as to enhance the TRL-stimulating activity of the flagellin.
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