Provided is a method for producing a desired highly unsaturated fatty acid ester composition efficiently and in high purity. Provided is a method for producing a highly unsaturated fatty acid ester composition, the method comprising purifying a crude composition containing a highly unsaturated fatty acid ester by column chromatography using an ODS silica gel filler, wherein the ODS silica gel filler has an average pore size of 8.5 to 11.9 nm and an average particle size of 15 to 229 μm.
Provided are a larval-fish feed with which it is possible to promote growth by improving the survival rate of larval fish, and a method for rearing fish. A larval-fish feed (40) comprises a body portion (10) configured from a fish-derived-component-containing formulation, and a gel-like coating portion (20) covering the body portion (10). This method for rearing fish includes a first step for feeding a biological bait to a larval fish, and a second step for feeding a larval-fish feed (40) to the larval fish, the second step being started after the start of the first step.
A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating
A23K 10/22 - Animal feeding-stuffs from material of animal origin from fish
A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
The present invention provides a method for treating or preventing a bacterial disease in fish, the method comprising intraperitoneally administering, to marine fish, an active ingredient selected from oxytetracycline or a salt thereof and doxycycline or a salt thereof.
SEASCAPE RESTORATIONS AUSTRALIA, T/A IMMERSION GROUP (Australia)
NISSUI CORPORATION (Japan)
Inventor
Statton, John
Elliott, Scott
Mitsuboshi, Toru
Ishida, Masashi
Abstract
A method for processing of algal biomass, comprising the step of subjecting the algal biomass to a stress chosen from: physical stress; osmotic stress; temperature stress; and/or preharvest light change stress, to produce the processed algal biomass, wherein the anti-methanogenic metabolite content of the processed algal biomass is higher after exposure to the stress than the anti-methanogenic metabolite content of the algal biomass before exposure to the stress.
SEASCAPE RESTORATIONS AUSTRALIA, T/A IMMERSION GROUP (Australia)
NISSUI CORPORATION (Japan)
Inventor
Statton, John
Elliott, Scott
Mitsuboshi, Toru
Ishida, Masashi
Abstract
A method for producing a cultured algal biomass comprising an antimethanogenic compound, wherein the method comprises the step of culturing the algal biomass: at a light intensity of from 1 µmols m-2.s-1to 40 µmols m-2.s-1; in a culture media supplemented with bromide; and/or in a culture media supplemented with vanadium.
METHOD FOR ADJUSTING MATURATION OF OVARY OF CRUSTACEAN, METHOD FOR PRODUCING HATCHED LARVAE OF CRUSTACEAN, METHOD FOR PRODUCING CRUSTACEAN, AND CRUSTACEAN
This method for adjusting the maturation of an ovary of crustacean comprises a breeding step for adjusting a breeding temperature of an individual crustacean having one or more tails to adjust a maturation frequency of the ovary. This method for producing the hatched larvae of crustacean comprises: a preparation step for preparing an individual crustacean that has reached an egg-producing weight and has one or more tails; and a breeding step for breeding the individual crustacean so as to set an immature period and a maturation period to freely selected periods, and obtaining hatched larvae from fertilized eggs released by the individual crustacean. In the breeding step, the breeding temperature of the individual crustacean is adjusted to adjust the maturation frequency of the ovary.
A highly unsaturated fatty acid or a highly unsaturated fatty acid ethyl ester that has been produced using as a feedstock oil a fat or oil that contains highly unsaturated fatty acids as constituent fatty acids and which has been reduced in the contents of environmental pollutants, wherein among the dioxins contained, polychlorinated dibenzoparadioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are contained in amounts of less than 0.05 pg-TEQ/g and coplanar PCBs (Co-PCBs) in amounts of less than 0.03 pg-TEQ/g. Also disclosed is a method for producing the highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester by the steps of removing free fatty acids and environmental pollutants by thin-film distillation from a feedstock oil, ethyl esterifying the resulting fat or oil, and refining the same by rectification and column chromatography.
C07C 51/44 - SeparationPurificationStabilisationUse of additives by change of the physical state, e.g. crystallisation by distillation
A23D 9/02 - Other edible oils or fats, e.g. shortenings or cooking oils characterised by the production or working-up
A23L 33/115 - Fatty acids or derivatives thereofFats or oils
A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
B01D 15/32 - Bonded phase chromatography, e.g. with normal bonded phase, reversed phase or hydrophobic interaction
C07C 51/47 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
C07C 67/03 - Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
C07C 67/54 - SeparationPurificationStabilisationUse of additives by change in the physical state, e.g. crystallisation by distillation
C07C 67/56 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
C07C 69/587 - Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
C11B 3/12 - Refining fats or fatty oils by distillation
C11B 3/16 - Refining fats or fatty oils by mechanical means
C11C 1/04 - Preparation of fatty acids from fats, fatty oils, or waxesRefining the fatty acids from fats or fatty oils by hydrolysis
C11C 3/00 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis
8.
VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS (VLCPUFA) FOR IMPROVING RETINA/COGNITIVE FUNCTIONS AND ATHEROSCLEROSIS
The present invention is directed to methods for treating macular degeneration, atherosclerosis, fatty liver, obesity, and cognitive ability, and more specifically to methods for treating macular degeneration, atherosclerosis, fatty liver, obesity, and cognitive ability using very long chain polyunsaturated fatty acids having 24 to 40 carbon atoms.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 3/08 - Drugs for disorders of the metabolism for glucose homeostasis
A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
PROBLEM: To provide a composition comprising highly enriched PUFA or its alkyl esters while containing fatty acid esters of 3-MCPD at adequately low concentrations and to provide an efficient method for producing the composition. MEANS FOR SOLVING: A composition that contains fatty acids or fatty acid alkyl esters as its major component, the composition containing highly unsaturated fatty acid or alkyl ester thereof, wherein the proportion of the highly unsaturated fatty acid in the constituent fatty acids of the composition is 50 area % or more and wherein the concentration of 3-MCPD as found upon analyzing the composition by American Oil Chemists' Society official method Cd 29b-13 assay A is less than 1.80 ppm.
The present invention addresses the problem of providing a composition that can be substituted for a synthetic ultraviolet absorber and that has an exceptional skin-problem-suppressing effect due to a component that absorbs ultraviolet rays of a wide range of wavelengths and is stable. A mycosporine (MYC) is used as an active ingredient of a composition for suppressing skin problems and/or a composition for suppressing active oxygen. The MYC preferably includes one or more substances selected from mycosporine-glutaminol-glucoside (MGGnol), mycosporine-glutamicol-glucoside (MGGcol), or mycosporine-glutamine (MGn). "Skin problems" may refer to problems triggered by ultraviolet irradiation or problems that occur irrespective of ultraviolet irradiation.
A61K 8/99 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
A61K 8/44 - Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfurSalts, esters or N-acylated derivatives thereof
National University Corporation Tokyo University of Marine Science and Technology (Japan)
Inventor
Yoshizaki, Goro
Takeuchi, Yutaka
Yazawa, Ryosuke
Kawamura, Wataru
Abstract
The transplant fish production method includes selecting a donor fish species, selecting first and second fish species which are a combination that could be sterile, producing a hybrid fish species of the selected first fish species and second fish species, and transplanting reproductive cells of the donor fish species into the produced hybrid fish species.
In the specification, a method for purifying a compound by column chromatography, and a method for optimizing the symmetry factor and theoretical plate number by allowing the slurry to settle and reducing the sedimentation volume of the slurry. A compound purified by such method is also provided.
B01D 15/20 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
B01D 15/32 - Bonded phase chromatography, e.g. with normal bonded phase, reversed phase or hydrophobic interaction
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
C07C 67/56 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
14.
METHOD FOR PRODUCING FROZEN BROCCOLI OR FROZEN CAULIFLOWER, AND METHOD FOR IMPROVING TEXTURE OF FROZEN BROCCOLI OR FROZEN CAULIFLOWER
The present invention provides a method for producing frozen broccoli or frozen cauliflower, the method comprising a step for curing harvested broccoli or cauliflower before freezing the same, in which the combination between time and temperature in the curing is, for example, any one of (A)-(C): (A) 96-192 hours at not lower than 10°C but lower than 15°C; (B) 12-96 hours at not lower than 15°C but lower than 25°C; and (C) 3-48 hours at not lower than 25°C but lower than 40°C. The present invention alternatively provides: a method for improving the texture of frozen broccoli or frozen cauliflower, the method comprising a step for curing harvested broccoli or cauliflower before freezing the same; or a frozen broccoli having a total pectin content of 11.0 mass% or more.
A23B 7/055 - FreezingSubsequent thawingCooling with addition of chemicals with direct contact between the food and the chemical, e.g. liquid N2, at cryogenic temperature
A23L 19/00 - Products from fruits or vegetablesPreparation or treatment thereof
The present invention provides a method for treating or preventing an oxidative stress-related disorder, the method comprising administering an effective amount of a very-long-chain polyunsaturated fatty acid (VLC-PUFA), a pharmaceutically functional derivative thereof or a pharmaceutically acceptable salt thereof to a subject in need of the treatment or prevention.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
16.
EMULSIFIED GEL, METHOD FOR PRODUCING EMULSIFIED GEL, PROCESSED MEAT-LIKE FOOD PRODUCT, AND METHOD FOR PRODUCING PROCESSED MEAT-LIKE FOOD PRODUCT
An emulsified gel containing a heat-denatured vegetable protein, water, and a fat or oil, where a content of the heat-denatured vegetable protein relative to a content of the fat or oil is 0.1 to 6% by mass; a method for producing an emulsified gel including the steps of: preparing an ungelled emulsion comprising a denatured vegetable protein, water, and a fat or oil; and heating the ungelled emulsion at a heating temperature of 60 to 100° C. to prepare an emulsified gel and/or emulsified gel precursor; a processed meat-like food product contains a textured vegetable protein and the emulsified gel; and a method for producing a processed meat-like food product including the step of: mixing the textured vegetable protein and the emulsified gel to prepare a mixture; are provided.
A23J 3/22 - Working-up of proteins for foodstuffs by texturising
A23D 7/005 - Edible oil or fat compositions containing an aqueous phase, e.g. margarines characterised by ingredients other than fatty acid triglycerides
METHOD FOR PRODUCING PROCESSED MEAT-LIKE FOOD PRODUCT, METHOD FOR IMPROVING JUICINESS OF PROCESSED MEAT-LIKE FOOD PRODUCT, METHOD FOR PREVENTING BREAKAGE OF EMULSIFIED GEL, AND FROZEN EMULSIFIED GEL
A method for producing a processed meat-like food product, method for improving juiciness of a processed meat-like food product, or method for preventing breakage of an emulsified gel during mixing includes the step of mixing a textured vegetable protein and a frozen product of an emulsified gel comprising a vegetable protein, water, and a fat or oil to prepare a mixture. A frozen emulsified gel contains a vegetable protein, water, and a fat or oil, wherein a content of the vegetable protein relative to a content of the fat or oil is 0.1 to 6% by mass. A processed meat-like food product contains a textured vegetable protein and the frozen emulsified gel.
The present production method provides a method for producing a fatty acid composition that contains polyunsaturated fatty acid (hereinafter referred to as PUFA) or ester derivative thereof. This production method comprises: storing a solvent in a container A to obtain an eluent under an inert gas atmosphere in the container A; purifying a fatty acid mixture containing PUFA or ester derivative thereof by chromatography using this eluent as a mobile phase to obtain a fraction containing PUFA or ester derivative thereof; and concentrating the fraction containing the PUFA or ester derivative thereof to obtain a fatty acid composition containing PUFA or ester derivative thereof.
Provided is a method for efficiently producing the desired highly unsaturated fatty acid ester composition in high purity. Provided is a method for producing a highly unsaturated fatty acid ester composition from an oil/fat composition, the method comprising: the removal, by subjecting the oil/fat composition to a first column chromatography, of some or all of at least one component having a relative value for the peak top retention time of 1.8-3.5 in the first column chromatography when the peak top retention time of the desired substance is 1.0; and the removal, by subjecting an eluate comprising the desired substance obtained by the first column chromatography to a second column chromatography, of some or all of at least one component having a relative value for the peak top retention time of 0.90-1.1 in the second column chromatography when the peak top retention time of the desired substance is 1.0.
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
B01D 15/32 - Bonded phase chromatography, e.g. with normal bonded phase, reversed phase or hydrophobic interaction
C11B 3/10 - Refining fats or fatty oils by adsorption
G01N 30/46 - Flow patterns using more than one column
G01N 30/84 - Preparation of the fraction to be distributed
Packaged fish meat, including: frozen minced fish meat and gas containing oxygen at 22% by volume or more as contents; frozen minced fish meat, wherein the amount of agglutinated frozen minced fish meat based on the entire amount of the frozen minced fish meat is 9.5% by mass or less; or a method for preventing the agglutination of frozen minced fish meat, wherein frozen minced fish meat is made to coexist with gas containing oxygen at 22% by volume or more.
B65D 81/18 - Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
21.
FEED FOR FARMED FISH INCLUDING TUNA FISH, FEED GROUP FOR FARMED FISH, METHOD FOR PRODUCING FEED FOR FARMED FISH INCLUDING TUNA FISH, AND METHOD FOR FARMING TUNA FISH
This feed for farmed fish including tuna fish is provided with a body part that is flatted so that the length along a thickness direction that is orthogonal to a width direction orthogonal to a length direction and the length direction becomes shorter than the length along the width direction, and the feed satisfies at least one item selected from the group consisting of items (A) and (B) mentioned below. (A) When the maximum length along the length direction is defined as a (mm), the maximum length along the width direction is defined as b (mm), and the maximum length along the thickness direction is defined as c (mm), a flattening rate f1 calculated in accordance with formula (1): f1 = a×b/c is 110 or more. (B) When the volume of the feed for farmed fish is defined as V (cm3) and the area of the feed for farmed fish when the feed is viewed in a plan view is defined as A (mm2), (V/A)1/2 is 0.110 or less.
A23K 40/30 - Shaping or working-up of animal feeding-stuffs by encapsulatingShaping or working-up of animal feeding-stuffs by coating
22.
METHOD FOR ESTIMATING AMOUNT RED MUSCLE, METHOD FOR ESTIMATING AMOUNT OF PYLORIC CAECUM, METHOD FOR PRODUCING PROCESSED PRODUCT OF SALTWATER FISH, METHOD FOR FARMING SALTWATER FISH, ANALYSIS DEVICE, IDENTIFIED PRODUCT OF SALTWATER FISH, AND PROCESSED PRODUCT GROUP OF SALTWATER FISH
This method for estimating an amount of red muscle comprises an information acquisition step for acquiring information pertaining to red muscle in the body of a saltwater fish via a nondestructive inspection, and an estimation step for estimating the amount of red muscle contained in said body on the basis of the information. An analysis device according to the present invention comprises a nondestructive inspection unit that acquires information pertaining to red muscle in the body of a saltwater fish via a nondestructive inspection, and a red muscle estimation unit that estimates the amount of red muscle in said body on the basis of the information.
G01N 23/046 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material using tomography, e.g. computed tomography [CT]
G01N 24/00 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
23.
INSPECTION METHOD AND MANUFACTURING METHOD FOR METALLIC PACKAGING CONTAINER, MANUFACTURING METHOD FOR PACKAGE BODY, PACKAGING CONTAINER ASSEMBLY, AND PACKAGE BODY ASSEMBLY
The present invention provides, inter alia, an inspection method and a manufacturing method for a metallic packaging container in which the leakage risk of a specific content, such as a composition containing a highly unsaturated fatty acid alkyl ester as a main component, is reduced. This method for inspecting and manufacturing a metallic packaging container includes: forming a body by molding and seam-welding sheet metal; attaching a top plate and a ground plate to the body so as to form the packaging container; and thereafter performing a burr inspection for inspecting the amount of burring with respect to a seam part of the body.
G01M 3/00 - Investigating fluid tightness of structures
B65D 8/04 - Containers having a curved cross-section formed by interconnecting or uniting two or more rigid, or substantially rigid, components made wholly or mainly of metal, plastics, wood or substitutes therefor characterised by wall construction or by connection between walls
G01B 21/30 - Measuring arrangements or details thereof, where the measuring technique is not covered by the other groups of this subclass, unspecified or not relevant for measuring roughness or irregularity of surfaces
G01M 3/04 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point
G01M 3/10 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point by observing bubbles in a liquid pool for containers, e.g. radiators
G01M 3/20 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material
24.
METHOD FOR SELECTING MIGRATORY FISH, METHOD FOR CULTURING SAME, AND MIGRATORY FISH
The present disclosure provides a method for selecting migratory fish to be sea surface-raised, the method including: (1) a step for, on the basis of trait information and genotype information obtained for sea surface-raised migratory fish, creating a regression equation for predicting the trait information from the genotype information; (2) a step for obtaining genotype information on freshwater-raised migratory fish; and (3) a step for applying the regression equation created in step (1) to the genotype information on the freshwater-raised migratory fish obtained in step (2) to select individuals predicted to possess the desired trait from among the freshwater-raised migratory fish.
Provided is a vegetable protein material with which it is possible to produce a food product having excellent texture and a method for producing a vegetable protein material with which it is possible to produce a food product having excellent texture. There is provided a defibrated product of an organized fibrous vegetable protein in which the mean length by number of the fibers contained therein is 10 mm or more, and the number-based content of fibers having an aspect ratio of less than 5 is 80% or less and a method for producing the defibrated product of an organized fibrous vegetable comprising a step for treating an organized fibrous vegetable protein in a gap between a first surface and a second surface facing the first surface and moving relative to the first surface.
A23J 3/22 - Working-up of proteins for foodstuffs by texturising
A23J 3/26 - Working-up of proteins for foodstuffs by texturising using extrusion or expansion
A23L 5/00 - Preparation or treatment of foods or foodstuffs, in generalFood or foodstuffs obtained therebyMaterials therefor
A23L 11/00 - Pulses, i.e. fruits of leguminous plants, for production of foodProducts from legumesPreparation or treatment thereof
26.
TEXTURIZED FIBROUS PLANT PROTEIN, DEFIBRATED PRODUCT OF TEXTURIZED FIBROUS PLANT PROTEIN, AND METHOD FOR IMPROVING DEFIBRATION RESISTANCE OF TEXTURIZED FIBROUS PLANT PROTEIN
The present invention provides a texturized fibrous plant protein which has improved defibration resistance. The present invention also provides a method for improving the defibration resistance of a texturized fibrous plant protein. Provided is a texturized fibrous plant protein comprising a pea-derived protein and a monovalent cation salt, said texturized fibrous plant protein comprising not less than 0.1 mass% but less than 2 mass% of the monovalent cation salt with respect to the pea-derived protein. Also provided is a method for improving the defibration resistance of a texturized fibrous plant protein, said method comprising a step for adding not less than 0.1 mass% but less than 2 mass% of a monovalent cation salt to a plant protein.
A cephalopod breeding method, which is for breeding cephalopod larvae in a breeding water tank, comprises, during the floating breeding period of the cephalopod larvae, forming a high concentration area where the salinity concentration is higher compared to seawater at the bottom of the breeding water tank and, after the passage of a predetermined time from the formation of the high concentration area, removing the high concentration area.
Provided is a method for rearing Artemias in a feeding water tank, wherein a feed containing a mollusk-derived feed is poured into the feeding water tank. Provided is a feed for Artemia that contains a mollusk-derived feed. Provided is an Artemia which satisfies at least one of the following requirements at 6 days of age: body width being greater than 0.183 mm; body height being greater than 0.179 mm; and volume greater than 0.099 mm3.
This cephalopod breeding method is a method for breeding cephalopod larvae in a rearing tank having a water changing means. The method includes a water-changing period during which the ratio of water changed by the water-changing means per day is 200% or more relative to the quantity of water in the rearing tank in a floating breeding period of the cephalopod larvae.
The present disclosure is: a free polyunsaturated fatty acid-containing composition, which comprises at least one free polyunsaturated fatty acid having 20 or more carbon atoms, the content being at least 80.0% of the fatty acids in the composition, and satisfies at least one selected from a group consisting of conditions (1) and (2): (1) the content of conjugated unsaturated fatty acid is 1.0% or less of the fatty acids in the composition, and (2) the Gardner color is less than 3+; and a manufacturing method for the free polyunsaturated fatty acid-containing composition comprising the preparation of a raw material composition containing at least one polyunsaturated fatty acid having 20 or more carbon atoms, and hydrolysis of a reaction solution containing the prepared raw material composition, a lower alcohol, water and an alkali catalyst at a temperature of 10° C. or lower.
A61K 31/201 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having one or two double bonds, e.g. oleic or linoleic acid
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
C07C 51/087 - Preparation of carboxylic acids or their salts, halides, or anhydrides from carboxylic acid anhydrides by hydrolysis
The present invention addresses the problem of providing a Eumycetes extract which can be produced industrially and which contains mycosporines (MYCs), in particular, mycosporine-glutamine (MGn). The present disclosure provides an extract of a Eumycetes cultured fungal body containing mycosporines (MCYs), the extract characterized in that the MYCs comprise mycosporine-glutamine (MGn). The MYCs may further comprise one or more selected from mycosporine glutaminol glucoside (MGGnol), mycosporine glutamicol glucoside (MGGcol), and mycosporine glutamic acid (Mga). Further, for the Eumycetes, a fungus belonging to the Hormonema genus may be used and, in particular, Hormonema macrosprum may be used.
The present disclosure addresses the problem of providing a fungal body of a fungus which belongs to the Aureobasidium genus and contains large quantities of Mycosporine-glutaminol-glucoside (MGGnol) and/or Mycosporine-glutamicol-glucoside (MGGcol). The present disclosure provides a fungal body of a fungus which belongs to the Aureobasidium genus and contains mycosporine-like amino acids (MAAs), said fungal body containing 25mg/g or more of MGGnol and/or MGGcol in a dried fungal body thereof. The fungus which belongs to the Aureobasidium genus may be selected from Aureobasidium subglaciale NSK56 strain (NITE BP-03771), Aureobasidium aerium NSK58 strain (NITE BP-03772) and Aureobasidium pullulans NSK228 strain (NITE BP-03773).
The present invention addresses the problem of efficiently extracting mycosporine-like amino acids (MAAs) from cells of a black yeast belonging to the family Dothioraceae, the Dothideales order, and obtaining a high-concentration extract of MAAs. The present disclosure provides a method for extracting MAAs into water, the method including a culture step for culturing Aureobasidium pullulans and an extraction step for extracting an MAAs fraction from the cultured cells of Aureobasidium pullulans, wherein one or more selected from the following (a), (b) and (c) are satisfied. (a) In the extraction step, the MAAs fraction is extracted in a polar solvent which is 40°C or higher. (b) Prior to the extraction step, a heating step, in which the cells are recovered from the culture medium after the culture step and the recovered cells are heated, is conducted. (c) In the culture step, the cells are cultured in a medium substantially free from ascorbic acid or a salt thereof and/or a peptone.
C12P 1/02 - Preparation of compounds or compositions, not provided for in groups , by using microorganisms or enzymesGeneral processes for the preparation of compounds or compositions by using microorganisms or enzymes by using fungi
C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
PROBLEM To provide a composition comprising highly enriched PUFA or its alkyl esters while containing fatty acid esters of 3-MCPD at adequately low concentrations and to provide an efficient method for producing the composition.
MEANS FOR SOLVING A composition that contains fatty acids or fatty acid alkyl esters as its major component, the composition containing highly unsaturated fatty acid or alkyl ester thereof, wherein the proportion of the highly unsaturated fatty acid in the constituent fatty acids of the composition is 50 area % or more and wherein the concentration of 3-MCPD as found upon analyzing the composition by American Oil Chemists' Society official method Cd 29b-13 assay A is less than 1.80 ppm.
A production method for a textured vegetable protein composite food, where the production method enables production of a textured vegetable protein composite food with improved texture; and a textured vegetable protein composite food with improved texture. The production method for a textured vegetable protein composite food, which contains a water-absorbable polysaccharide thickener and a water-absorbable textured vegetable protein, includes: (1) a step of allowing the water-absorbable polysaccharide thickener to absorb water by adding water thereto in the absence of the water-absorbable textured vegetable protein to give a hydrated polysaccharide thickener; and (2) a step of adding the water-absorbable textured vegetable protein to the hydrated polysaccharide thickener and mixing together to give a textured vegetable protein composite, where, in the step (1), 80% by mass or more of water to be used in the step (1) is added to 1 kg or more of the water-absorbable polysaccharide thickener within 30 seconds.
A23L 29/238 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of vegetable origin from seeds, e.g. locust bean gum or guar gum
A23L 29/256 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
A23L 29/262 - CelluloseDerivatives thereof, e.g. ethers
A23L 29/269 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
The present invention provides a composition for relieving or preventing the symptoms of allergic rhinitis or allergic conjunctivitis, etc., the composition containing dihomo-γ-linolenic acid (DGLA) as an active ingredient.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
A61K 31/683 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
The present invention provides: a fish paste substitute which is easy to handle in the production of a paste product; a paste product precursor using the fish paste substitute; and a method for producing a paste product using the paste product precursor. Provided are: a fish paste substitute which is a frozen material comprising water and at least one component selected from the group consisting of thermally coagulable β-1,3- glucan, starch, cellulose and a cellulose derivative; a paste product precursor which is a mixture of the fish paste substitute and a frozen fish paste; and a method for producing a paste product, the method comprising a step A for preparing a frozen fish paste, a step B for preparing a fish paste substitute that is a frozen material, and a step C for pulverizing and mixing the frozen fish paste and the fish paste substitute together to produce a paste product precursor.
A23L 29/269 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
38.
Microbial Oil/Lipid and Method for Producing Microbial Oil/Lipid
To provide a microbial oil that contains eicosapentaenoic acid (EPA) at a high concentration and can effectively exert the function of EPA. A microbial oil containing EPA and docosahexaenoic acid (DHA), in which the content of EPA is 38% by area or greater relative to the total fatty acids and which has at least one fatty acid ratio selected from the group consisting of (a) to (c): (a) a ratio of the content of EPA to the content of DHA of 1.7 or more; (b) a ratio of the content of fatty acid(s) having 18 carbon atoms to the content of fatty acid(s) having 20 carbon atoms of 0.3 or less; and (c) a ratio of the content of fatty acid(s) having 18 carbon atoms to the content of fatty acid(s) having 22 carbon atoms of 1.5 or less.
C12P 7/64 - FatsFatty oilsEster-type waxesHigher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl groupOxidised oils or fats
C12N 1/12 - Unicellular algaeCulture media therefor
39.
PRODUCTION METHOD FOR PROTEIN PROCESSED FOOD, PRODUCTION DEVICE FOR PROTEIN PROCESSED FOOD, AND PROTEIN PROCESSED FOOD
In a production method for a protein processed food, a tubular body having an outlet for a protein processed food at one end, and a core material arranged inside the tubular body and extending to at least the outlet along an axial direction of the tubular body are used, a mixture is supplied between the tubular body and the core material while the core material is rotated around the axial direction of the tubular body, the mixture is extruded toward the outlet, and at a side further upstream than the outlet, the mixture is internally heated and coagulated, and the coagulated hollow protein processed food is discharged from the outlet.
In the specification, a method for purifying a compound by column chromatography, and a method for optimizing the symmetry factor and theoretical plate number by allowing the slurry to settle and reducing the sedimentation volume of the slurry. A compound purified by such method is also provided.
B01D 15/20 - Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to the conditioning of the sorbent material
B01D 15/32 - Bonded phase chromatography, e.g. with normal bonded phase, reversed phase or hydrophobic interaction
B01J 20/28 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof characterised by their form or physical properties
C07C 67/56 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
41.
COMPOSITION FOR EXTERNAL USE ON SKIN FOR INFLAMMATORY DISEASES
[Problem] To provide a composition for external skin use that has anti-inflammatory and antiallergic activity and is very safe. [Solution] A composition for external skin use for inflammatory diseases contains dihomo-gamma-linolenic acid (DGLA) as the active ingredient thereof. It is preferable for the DGLA to be present as a glyceride, a phospholipid, or an alkyl ester. The amount of DGLA contained in the composition for external use is 0.1-50 wt %.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/06 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K 31/683 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 31/7032 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyl-diacylglycerides, lactobionic acid, gangliosides
42.
VERY-LONG-CHAIN POLYUNSATURATED FATTY ACIDS (VLCPUFA) FOR IMPROVING RETINA/COGNITIVE FUNCTIONS AND ATHEROSCLEROSIS
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (USA)
NISSUI CORPORATION (Japan)
Inventor
Yang, Zhi-Hong
Remaley, Alan Thomas
Rojulpote, Krishna Vamsi S.
Tang, Jingrong
Yamazaki, Isao
Yamaguchi, Hideaki
Sato, Seizo
Abstract
The present invention is directed to methods for treating macular degeneration, atherosclerosis, fatty liver, obesity, and cognitive ability, and more specifically to methods for treating macular degeneration, atherosclerosis, fatty liver, obesity, and cognitive ability using very long chain polyunsaturated fatty acids having 24 to 40 carbon atoms.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
The purpose of the present invention is to provide very long chain polyunsaturated fatty acids and/or derivatives thereof. Substance production of very long chain polyunsaturated fatty acids and/or derivatives thereof has been possible by the conventional technology. However, concentrations of the produced substances have been low. The substance production of very long chain polyunsaturated fatty acids and/or derivatives thereof has been possible. However, the substances produced cannot be obtained in sufficient concentrations and cannot be used as compositions. The present invention provides very long chain polyunsaturated fatty acids and/or derivatives thereof with increased concentrations. Moreover, the object of the present invention is to provide a composition comprising very long chain polyunsaturated fatty acids and/or derivatives thereof.
C11C 3/04 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis by esterification of fats or fatty oils
C12N 15/81 - Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
The present invention provides: an endurance-improving composition that contains, as an active ingredient, triglycerides containing highly unsaturated fatty acids and medium-chain fatty acids as constituent fatty acids; and an endurance-improving food composition, food additive, or the like that contains said composition.
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
A23L 33/115 - Fatty acids or derivatives thereofFats or oils
The present invention provides a method for producing a very-long-chain polyunsaturated fatty acid, the method comprising reacting a compound represented by formula II of R1-MgX1and a compound represented by formula III of X22mm-X in a solvent to obtain a compound represented by formula I of R12mm-X.
C07D 309/04 - Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
C07C 67/30 - Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
C07C 69/587 - Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
46.
PROCESSED MEAT-LIKE FOOD, CONNECTIVE TISSUE-LIKE TEXTURE IMPARTING AGENT, METHOD FOR TEXTURE IMPROVEMENT OF PROCESSED MEAT-LIKE FOOD, AND PRODUCTION METHOD FOR PROCESSED MEAT-LIKE FOOD
A processed meat-like food containing a connective tissue-like texture imparting agent and a textured vegetable protein, and having texture closer to processed meat foods produced from meat as a main raw material; a connective tissue-like texture imparting agent capable of imparting to a processed meat-like food a texture closer to processed meat foods produced from meat as a main raw material; a method for texture improvement of a processed meat-like food containing a textured vegetable protein, where a connective tissue-like texture imparting agent is added, the method approximating the texture of a processed meat-like food to processed meat foods produced from meat as a main raw material; and a production method for a processed meat-like food, including mixing a connective tissue-like texture imparting agent and a textured vegetable protein, the method resulting in a processed meat-like food having texture closer to those of processed meat foods produced from meat.
Provided are: an emulsified gel that is advantageous for the progression of gelation during production thereof; a production method for said emulsified gel; a processed meat-like food containing the emulsified gel; and a production method for said processed meat-like food containing the emulsified gel. The present invention provides: an emulsified gel that contains a heat-denatured vegetable protein, water, and fats and oils and in which the heat-denatured vegetable protein content relative to the fat and oil content is 0.1-6 mass%; a production method for an emulsified gel, the method including a step for obtaining an ungelled emulsion containing a denatured vegetable protein, water, and fats and oils, and a step for obtaining an emulsified gel and/or an emulsified gel precursor by heating the ungelled emulsion at a heating temperature of 60-100°C; a processed meat-like food containing a textured vegetable protein and the emulsified gel; and a production method for a processed meat-like food, the method including a step for obtaining a mixture by mixing a textured vegetable protein and the emulsified gel.
A23L 13/00 - Meat productsMeat mealPreparation or treatment thereof
A23L 29/244 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of vegetable origin from corms, tubers or roots, e.g. glucomannan
A23L 29/262 - CelluloseDerivatives thereof, e.g. ethers
A23L 29/269 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of microbial origin, e.g. xanthan or dextran
48.
PROCESSED MEAT-LIKE FOOD PRODUCTION METHOD, METHOD FOR ENHANCING JUICY FEELING OF PROCESSED MEAT-LIKE FOOD, METHOD FOR PREVENTING BREAKAGE OF EMULSIFIED GEL, AND FROZEN EMULSIFIED GEL
Provided are an emulsified gel favorable for advancing gelatification during production, a method for producing the emulsified gel, processed meat-like food including the emulsified gel, and a method for producing processed meat-like food including the emulsified gel. The processed meat-like food production method, method for enhancing the juicy feeling of processed meat-like food, and method for preventing breakage of an emulsified gel during mixing according to the present invention involve a step for mixing texturized plant protein and a frozen product of an emulsified gel including plant protein, water, and fat/oil to obtain a mixture. This frozen emulsified gel includes plant protein, water, and fat/oil, wherein the content of the plant protein is 0.1-6% by mass based on the content of the fat/oil. This processed meat-like food includes texturized plant protein and the frozen emulsified gel.
Provided are: packaged fish meat in which agglutination of the frozen minced fish meat contents is inhibited; frozen minced fish meat in which agglutination of the frozen minced fish meat is inhibited; and a method for preventing agglutination of frozen minced fish meat. Provided are: packaged fish meat comprising, as contents, frozen minced fish meat and a gas comprising at least 22 volume% of oxygen; frozen minced fish meat covered with gas comprising at least 22 volume% of oxygen; frozen minced fish meat in which the amount of agglutinated frozen minced fish meat with respect to the entire amount of frozen minced fish meat is 9.5 mass% or less; and a method for preventing agglutination of frozen minced fish meat wherein frozen minced fish meat and a gas comprising at least 22 volume% of oxygen are allowed to coexist.
B65D 85/50 - Containers, packaging elements or packages, specially adapted for particular articles or materials for living organisms, articles or materials sensitive to changes of environment or atmospheric conditions, e.g. land animals, birds, fish, water plants, non-aquatic plants, flower bulbs, cut flowers or foliage
A vaccination method in which an injection needle is inserted into a muscle in the dorsal region or tail region of a farmed fish to inoculate the farmed fish with a vaccine solution.
A highly unsaturated fatty acid or a highly unsaturated fatty acid ethyl ester that has been produced using as a feedstock oil a fat or oil that contains highly unsaturated fatty acids as constituent fatty acids and which has been reduced in the contents of environmental pollutants, wherein among the dioxins contained, polychlorinated dibenzoparadioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are contained in amounts of less than 0.05 pg-TEQ/g and coplanar PCBs (Co-PCBs) in amounts of less than 0.03 pg-TEQ/g. Also disclosed is a method for producing the highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester by the steps of removing free fatty acids and environmental pollutants by thin-film distillation from a feedstock oil, ethyl esterifying the resulting fat or oil, and refining the same by rectification and column chromatography.
C07C 51/47 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
C07C 67/03 - Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
C07C 67/54 - SeparationPurificationStabilisationUse of additives by change in the physical state, e.g. crystallisation by distillation
C07C 67/56 - SeparationPurificationStabilisationUse of additives by solid-liquid treatmentSeparationPurificationStabilisationUse of additives by chemisorption
C07C 69/587 - Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
C11B 3/12 - Refining fats or fatty oils by distillation
C11C 1/04 - Preparation of fatty acids from fats, fatty oils, or waxesRefining the fatty acids from fats or fatty oils by hydrolysis
C11C 3/00 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis
A23D 9/02 - Other edible oils or fats, e.g. shortenings or cooking oils characterised by the production or working-up
A23L 33/115 - Fatty acids or derivatives thereofFats or oils
A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
B01D 15/32 - Bonded phase chromatography, e.g. with normal bonded phase, reversed phase or hydrophobic interaction
C11B 3/16 - Refining fats or fatty oils by mechanical means
52.
Composition containing highly unsaturated fatty acid or alkyl ester thereof and a method for producing the same
PROBLEM To provide a composition comprising highly enriched PUFA or its alkyl esters while containing fatty acid esters of 3-MCPD at adequately low concentrations and to provide an efficient method for producing the composition.
MEANS FOR SOLVING A composition that contains fatty acids or fatty acid alkyl esters as its major component, the composition containing highly unsaturated fatty acid or alkyl ester thereof, wherein the proportion of the highly unsaturated fatty acid in the constituent fatty acids of the composition is 50 area % or more and wherein the concentration of 3-MCPD as found upon analyzing the composition by American Oil Chemists' Society official method Cd 29b-13 assay A is less than 1.80 ppm.
The present disclosure is: a free polyunsaturated fatty acid-containing composition, which comprises at least one free polyunsaturated fatty acid having 20 or more carbon atoms, the content being at least 80.0% of the fatty acids in the composition, and satisfies at least one selected from a group consisting of conditions (1) and (2): (1) the content of conjugated unsaturated fatty acid is 1.0% or less of the fatty acids in the composition, and (2) the Gardner color is less than 3+; and a manufacturing method for the free polyunsaturated fatty acid-containing composition comprising the preparation of a raw material composition containing at least one polyunsaturated fatty acid having 20 or more carbon atoms, and hydrolysis of a reaction solution containing the prepared raw material composition, a lower alcohol, water and an alkali catalyst at a temperature of 10° C. or lower.
A61K 31/201 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having one or two double bonds, e.g. oleic or linoleic acid
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
C07C 51/087 - Preparation of carboxylic acids or their salts, halides, or anhydrides from carboxylic acid anhydrides by hydrolysis
C07C 51/09 - Preparation of carboxylic acids or their salts, halides, or anhydrides from carboxylic acid esters or lactones
A61K 31/201 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having one or two double bonds, e.g. oleic or linoleic acid
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
C07C 51/087 - Preparation of carboxylic acids or their salts, halides, or anhydrides from carboxylic acid anhydrides by hydrolysis
A method for pickling a marine product under conditions satisfying the following a) to c): a) the total ionic strength during treatment is from 0.2 to 0.8 mol/kg; b) the total sodium chloride concentration is less than 1.5% by weight; and c) the pH of the pickled shrimp meat is from 6.5 to 8.6, where, the total ionic strength and total sodium chloride concentration mean the ionic strength and the sodium chloride concentration with respect to the sum of the weight of the marine products and the weight of the water of the pickling solution, assuming that the weight of the marine products is the weight of water.
[Problem] To provide a composition for external skin use that has anti-inflammatory and antiallergic activity, and is very safe. [Solution] A composition for external skin use for inflammatory diseases contains dihomo-gamma-linolenic acid (DGLA) as the active ingredient thereof. It is preferable for the DGLA to be present as a glyceride, a phospholipid, or an alkyl ester. The amount of DGLA contained in the composition for external use is 0.1-50 wt %.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/06 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K 31/683 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
A61K 31/7032 - Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyl-diacylglycerides, lactobionic acid, gangliosides
58.
METHOD OF PRODUCING DOCOSAHEXAENOIC ACID CONTAINING GLYCERIDE USING A LIPASE HYDROLYSIS REACTION
The present invention provides a method of producing a composition containing docosahexaenoic acid as a constituent fatty acid of glycerides, comprising hydrolyzing a feedstock oil containing glycerides comprising docosahexaenoic acid as a constituent fatty acid by action of a Candida cylindracea derived lipase and a partial glyceride lipase, thereby increasing the proportion of docosahexaenoic acid in glyceride fractions, wherein the lipase hydrolysis reaction is performed at a temperature no higher than 30° C. for a period no longer than 15 hours.
C12P 7/64 - FatsFatty oilsEster-type waxesHigher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl groupOxidised oils or fats
C12N 9/20 - Triglyceride splitting, e.g. by means of lipase
59.
Composition containing highly unsaturated fatty acid or alkyl ester thereof and a method for producing the same
PROBLEM To provide a composition comprising highly enriched PUFA or its alkyl esters while containing fatty acid esters of 3-MCPD at adequately low concentrations and to provide an efficient method for producing the composition.
MEANS FOR SOLVING A composition that contains fatty acids or fatty acid alkyl esters as its major component, the composition containing highly unsaturated fatty acid or alkyl ester thereof, wherein the proportion of the highly unsaturated fatty acid in the constituent fatty acids of the composition is 50 area % or more and wherein the concentration of 3-MCPD as found upon analyzing the composition by American Oil Chemists' Society official method Cd 29b-13 assay A is less than 1.80 ppm.
The present invention provides a composition for improving lymphatic circulation, which contains a component selected from at least one highly unsaturated fatty acid, salt thereof, and ester thereof as an active ingredient. The present invention also provides a composition for improving lymphatic circulation, which contains as active ingredients a triglyceride comprising the at least one highly unsaturated fatty acid as a constituent fatty acid and a triglyceride comprising the at least one middle chain fatty acid as a constituent fatty acid. The present invention also provides a composition for improving lymphatic circulation, which contains as an active ingredient a triglyceride comprising the at least one highly unsaturated fatty acid and the at least one middle chain fatty acid as constituent fatty acids.
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
61.
Composition containing highly unsaturated fatty acid or alkyl ester thereof and a method for producing the same
PROBLEM To provide a composition comprising highly enriched PUFA or its alkyl esters while containing fatty acid esters of 3-MCPD at adequately low concentrations and to provide an efficient method for producing the composition.
MEANS FOR SOLVING A composition that contains fatty acids or fatty acid alkyl esters as its major component, the composition containing highly unsaturated fatty acid or alkyl ester thereof, wherein the proportion of the highly unsaturated fatty acid in the constituent fatty acids of the composition is 50 area % or more and wherein the concentration of 3-MCPD as found upon analyzing the composition by American Oil Chemists' Society official method Cd 29b-13 assay A is less than 1.80 ppm.
PROBLEM To provide a composition comprising highly enriched PUFA or its alkyl esters while containing fatty acid esters of 3-MCPD at adequately low concentrations and to provide an efficient method for producing the composition.
MEANS FOR SOLVING A composition that contains fatty acids or fatty acid alkyl esters as its major component, the composition containing highly unsaturated fatty acid or alkyl ester thereof, wherein the proportion of the highly unsaturated fatty acid in the constituent fatty acids of the composition is 50 area % or more and wherein the concentration of 3-MCPD as found upon analyzing the composition by American Oil Chemists' Society official method Cd 29b-13 assay A is less than 1.80 ppm.
[Problem] Provision of a composition for external use on skin that is safe to use and has an anti-inflammatory and anti-allergic actions. [Solution] A composition for external use on skin in the treatment of inflammatory disease which comprises dihomo-γ-linolenic acid (DGLA) as an active ingredient. The DGLA is preferably contained as a glyceride, a phospholipid, or an alkyl ester. The composition for external use contains DGLA in an amount of 0.1-50 wt %.
A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
A61K 31/22 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 47/06 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
A61K 31/683 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
64.
HIGHLY UNSATURATED FATTY ACID OR HIGHLY UNSATURATED FATTY ACID ETHYL ESTER WITH REDUCED ENVIRONMENTAL POLLUTANTS, AND METHOD FOR PRODUCING SAME
A highly unsaturated fatty acid or a highly unsaturated fatty acid ethyl ester that has been produced using as a feedstock oil a fat or oil that contains highly unsaturated fatty acids as constituent fatty acids and which has been reduced in the contents of environmental pollutants, wherein among the dioxins contained, polychlorinated dibenzoparadioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) are contained in amounts of less than 0.05 pg-TEQ/g and coplanar PCBs (Co-PCBs) in amounts of less than 0.03 pg- TEQ/g. Also disclosed is a method for producing the highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester by the steps of removing free fatty acids and environmental pollutants by thin-film distillation from a feedstock oil, ethyl esterifying the resulting fat or oil, and refining the same by rectification and column chromatography.
A23D 9/00 - Other edible oils or fats, e.g. shortenings or cooking oils
A23L 33/115 - Fatty acids or derivatives thereofFats or oils
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61K 31/232 - Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
C07C 69/587 - Monocarboxylic acid esters having at least two carbon-to-carbon double bonds
C11B 3/12 - Refining fats or fatty oils by distillation
C11C 1/00 - Preparation of fatty acids from fats, fatty oils, or waxesRefining the fatty acids
C11C 3/04 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis by esterification of fats or fatty oils
65.
A COMPOSITION CONTAINING AN HIGHLY UNSATURATED FATTY ACID OR ALKYL ESTER THEREOF AND A METHOD FOR PRODUCING THE SAME
Provided are: a composition containing a highly concentrated polyunsaturated fatty acid or a polyunsaturated fatty acid alkyl ester, in which the concentration of a 3-MCPD fatty acid ester is sufficiently low; and a method for efficiently producing same. The present composition containing a fatty acid or a fatty acid alkyl ester as a main component, contains a polyunsaturated fatty acid or an alkyl ester thereof, wherein the proportion of the polyunsaturated fatty acid in the constituent fatty acids of the composition is 50 area% or more, and the composition has a 3-MCPD concentration of less than 1.80 ppm as analyzed according to the American Oil Chemists' Society's official method Cd29b-13 assay A.
This Description provides a method for purifying a compound using column chromatography and provides a method for optimizing the symmetry coefficient and theoretical number of plates by sedimenting a slurry and reducing the sedimentation volume of the slurry. Also provided are compounds that have been purified by these methods.
Disclosed is a method for producing the highly unsaturated fatty acid or highly unsaturated fatty acid ethyl ester by the steps of removing free fatty acids and environrnental pollutants by thin-film distillation from a feedstock oil, ethyl esterifying the resulting fat or oil, and refining the same by rectification and column chromatography.
C11B 3/12 - Refining fats or fatty oils by distillation
C11C 1/00 - Preparation of fatty acids from fats, fatty oils, or waxesRefining the fatty acids
C11C 3/00 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis
C11C 3/04 - Fats, oils or fatty acids obtained by chemical modification of fats, oils or fatty acids, e.g. by ozonolysis by esterification of fats or fatty oils
The present invention provides a method for treating or preventing an oxidative stress-related disorder, the method comprising administering an effective amount of a very-long-chain polyunsaturated fatty acid (VLC-PUFA), a pharmaceutically functional derivative thereof or a pharmaceutically acceptable salt thereof to a subject in need of the treatment or prevention.
A61K 31/20 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid
A61K 31/202 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having three or more double bonds, e.g. linolenic acid
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia