Tongji Hospital affiliated to Tongji Medical College of Huazhong University of Science & Technology (China)
Inventor
Cheng, Jing
Chen, Huibing
Xie, La
Xiao, Yaru
Liu, Xiangping
Wu, Jie
Li, Zheying
Wu, Hui
Fu, Jingjing
Abstract
The present application provides a VR-based standardized training system for multi-person online cooperated first-aid nursing of trauma, which is used for providing medical staff with an efficient and convenient-to-update and maintain standardized training environment for multi-person online cooperated first-aid nursing of trauma by introducing the VR technology, so as to significantly improve the training effect of the first aid of trauma of the medical staff. The system includes: a teacher-side processing device, which is used for performing task configuration processing on a standardized training task for multi-person online cooperated first-aid nursing of trauma; a management-side server device, which is used for configuring a VR environment of the standardized training task for multi-person online cooperated first-aid nursing of trauma for a trainee-side VR device according to the configuration content of the task configuration processing performed by the teacher-side processing device; and the trainee-side VR device.
SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (China)
TONGJI HOSPITAL AFFILIATED TO TONGJI MEDICAL COLLEGE OF HUAZHONG UNIVERSITY OF SCIENCE & TECHNOLOGY (China)
Inventor
Wang, Daowen
Jiang, Xiangrui
Chen, Chen
Jiang, Hualiang
Shen, Jingshan
Abstract
The present invention relates to a sulfonylurea compound represented by formula I, a preparation method therefore, and an application thereof. The compound of the present invention has soluble epoxide hydrolase (sEH) inhibitory activity and can increase the level of epoxyeicosatrienoic acids (EETs) so as to alleviate inflammatory responses, and thus can be used for preventing and treating heart failure. The preparation method of the present invention has the technical advantages of simple steps, high yield, and easily available raw materials.
C07C 311/57 - Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
C07C 311/54 - Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
C07C 311/56 - Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
C07C 311/58 - Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
C07C 311/59 - Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of rings other than six-membered aromatic rings
C07C 311/60 - Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
C07D 207/267 - 2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
C07D 209/52 - Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
patents
