The system includes an array of electrodes and a stimulator coupled to the array of electrodes by at least one flexible wire. The array of electrodes are disposed on a flexible carrier configured to wrap around a hypoglossal nerve of a patient. The array of electrodes include a first electrode, a second electrode, and a third electrode. The stimulator includes a control circuit configured to generate a stimulation signal. The stimulator is configured to receive a communication from an external device for selecting at least one of the first electrode, the second electrode, and the third electrode that will participate in stimulating the hypoglossal nerve of the patient.
The invention disclosed herein relates to a system (1) for implanting a neurostimulation lead (2) in a subject's head and facial tissue (3), the system (1) comprising: a stimulation lead (2) configured for implantation in said tissue (3); an introducer (4) configured for temporary insertion into said tissue (3) and comprising a Tube portion (5); a tunneling tool (6) configured for temporary insertion into said tissue (3) and comprising a shaft (7), a shaft tip (9) releasably mounted to the shaft (7), and a pull suture (8) connected to the releasable shaft tip (9); a first trocar (10) configured for insertion into the introducer (4), the first trocar (10) comprising a receiving structure (11) for receiving and retaining the shaft tip (9) of the tunneling tool (6); a guide tube (12) configured for insertion into the introducer (4); a second trocar (13) configured for insertion into the guide tube (12); and a lead holder (14) configured for inserting the stimulation lead (2) through the guide tube (12) into said tissue. The invention further relates to a method of implanting a stimulation lead (2) in a subject's head and facial tissue (3) using said system (1).
The invention disclosed herein relates to a neurostimulation system for treating head and facial pain, the system comprising: an external unit configured for a location external to a subject's body; and an implant unit configured for implantation inside the subject's body; wherein the external unit comprises: a primary coil configured to transmit a stimulation signal to the implant unit; and a power source; wherein the implant unit comprises: a plurality of electrodes; and a secondary coil in electrical communication with the plurality of electrodes, wherein the secondary coil is configured to receive the stimulation signal from the primary coil; and wherein the system is configured, for each stimulation event of a series of stimulation events, to select a sub-group of electrodes from the plurality of electrodes for stimulation delivery, and/or to select a set of stimulation parameter values for stimulation delivery. According to another aspect, the invention relates to a method for selecting a stimulation delivery pattern for an implant unit of said neurostimulation system.
Disclosed herein is a neurostimulation system for treating head pain, the system comprising: an implant unit configured for implantation inside a subject's (700) body; an external unit configured for a location external to the subject's (700) body; and a charging and programming unit; wherein the external unit comprises: a processor; a power source (220); and a primary transmission unit (230) in electrical communication with the power source (220) and the processor; wherein the implant unit comprises: at least one lead (310); at least one pair of modulation electrodes (320) attached to the at least one lead (310); and a secondary transmission unit (330) in electrical communication with the at least one lead (310); and wherein the processor is configured to establish a coupling between the primary transmission unit (230) and the secondary transmission unit (330) and to transmit power from the power source (220) to the implant unit via said coupling. According to another aspect of the present disclosure, an implant unit for use in a neurostimulation system is described, wherein the implant unit is configured for implantation inside a subject's (700) body through an incision (600) subject's (700) skin, and wherein the implant unit is further configured for implantation inside the subject's (700) body through a tunnel (610). According to yet another aspect of the disclosure, a method for electrical stimulation of neuromuscular tissue using a neurostimulation system is described herewith, the method comprising: generating an electrical stimulation pattern with an external unit, the electrical stimulation pattern comprising at least one modulation signal; delivering the electrical stimulation pattern to an implant unit located inside a subject's (700) body; adjusting the electrical stimulation pattern, wherein adjusting the electrical stimulation pattern comprises increasing or decreasing a voltage, a current amplitude, a pulse frequency and/or a pulse width of the electrical stimulation pattern. Such a method may be valuable, for example, in pain management, where the propagation of pain signals is undesired.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Surgical and medical apparatus and instruments; medical
devices for the diagnosis and treatment of headaches and
related disorders, as well as their component parts;
injection instruments for injecting nerve blocks in patients
with headaches and related disorders; injection instruments
using MRI/CT guidance and information for injections into
the nerve structures of the head and brain; injection device
for pharmaceuticals; injection instruments for injecting
electrical nerve stimulators; activation devices for the
activation of implantable stimulators; activation devices
for the wireless activation of implantable stimulators;
patient screening kits for the diagnosis of headaches and
related disorders, consisting of medical devices for the
diagnosis of headaches and related disorders, electronic
data loggers for recording information collected in the
diagnosis of headaches and related disorders, and computer
software for data management for use with medical devices
for the diagnosis of headaches and related disorders, all
sold as a unit. Scientific and research services in the field of medical
equipment for the treatment of headaches and related
disorders; technical support services in the form of
technical diagnosis in connection with the malfunction of
medical equipment for the treatment of headaches and related
disorders; medical research; design and development of
medical diagnostic apparatus for use in the treatment of
headaches and related disorders; design and development of
medical technologies for the treatment of headaches and
related disorders. Medical services; medical treatments; therapy to treat
headaches and related disorders; medical services, namely
diagnosis and treatment of headaches and related disorders;
medical consultancy services in the field of headaches and
related disorders, provided to patients and physicians;
provision of medical information in the field of headaches
and related disorders; conducting studies on headaches and
related disorders, for the purpose of medical diagnosis or
treatment; medical equipment rental.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Surgical and medical apparatus and instruments namely pulse generators for neurostimulation; medical devices for the diagnosis and treatment of headaches and related neurological disorders, in the form of disposable electrodes; injection needles for medical use in the injection of nerve blocks in patients suffering from headaches and related neurological disorders; medical injection needle using MRI/CT guidance and information for injections into the nerve structures of the head and brain; medical injection needle for pharmaceuticals products; medical injection needles for injecting electrical nerve stimulators; medical devices for activating implantable nerve stimulators; medical devices for wireless activation of implantable nerve stimulators; patient screening kits for the diagnosis of headaches and related neurological disorders, consisting of medical devices for the diagnosis of headaches and related neurological disorders, electronic data loggers for recording information collected in the diagnosis of headaches and related disorders, and computer software for data management for use with medical devices for the diagnosis of headaches and related disorders, all sold as a unit. (1) Scientific and research services in the field of medical equipment for the treatment of headaches and related disorders; technical support services in the form of technical diagnosis in connection with the malfunction of medical equipment for the treatment of headaches and related disorders; medical research; design and development of medical diagnostic apparatus for use in the treatment of headaches and related disorders; design and development of medical technologies for the treatment of headaches and related disorders.
(2) Medical services for the treatment of headaches and related neurological disorders; medical treatments, namely medical services for the treatment of headaches and related neurological disorders; therapy to treat headaches and related disorders; medical services, namely diagnosis and treatment of headaches and related disorders; medical consultancy services in the field of headaches and related disorders, provided to patients and physicians; provision of medical information in the field of headaches and related disorders; conducting studies on headaches and related disorders, for the purpose of medical diagnosis or treatment; medical equipment rental.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical services; medical treatments; therapy for treating
headaches and related disorders; medical services, namely,
diagnosis and treatment of headaches and related disorders;
medical consultancy in the fields of headaches and related
disorders, provided to patients and doctors; providing
medical information in the field of headaches and related
disorders; medical diagnostic services and medical treatment
based on study results.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Surgical and medical apparatus and instruments; medical
implants; implants for neurostimulation; apparatus for
stimulating nerves; electrical neurostimulators; medical
devices for the diagnosis and treatment of headaches and
related disorders, as well as component parts thereof;
electrostimulation devices for treatment of headache and
related disorders, i.e. implantable muscle or nerve
stimulators consisting of artificial materials, and devices
for implanting stimulators; activation devices for
activating implantable stimulators; activation devices for
wireless activation of implantable stimulators; activation
devices with rechargeable batteries for activating
implantable stimulators; external stimulators for activating
implantable stimulators; patient screening kits for
diagnosis of headache and related disorders, consisting of
medical devices for diagnosis of headache and related
disorders, electronic data recorders for recording
information collected in the diagnosis of headache and
related disorders, and computer software for management of
data for use with medical devices for diagnosis of headache
and related disorders, all sold as a set; electrical
stimulation systems for medical use; injection instruments
for nerve block injection in patients suffering from
headaches and related disorders; nasal injection instruments
using MRI/CT guidance and information for injections in head
and brain nerve structures; injection devices for
pharmaceutical products. Scientific services and research services in the field of
medical equipment for the treatment of headaches and related
disorders; technical support services in the nature of
technical diagnosis relating to malfunction of medical
equipment used for the treatment of headaches and related
disorders; medical research; designing and developing
medical diagnosis apparatus for the treatment of headaches
and related disorders; designing and developing medical
technologies for the treatment of headaches and related
disorders. Medical services; medical treatments; therapy for treating
headaches and related disorders; medical services, namely,
diagnosis and treatment of headaches and related disorders;
medical consultancy in the fields of headaches and related
disorders, provided to patients and doctors; providing
medical information in the field of headaches and related
disorders; conducting studies on headaches and related
disorders, for medical diagnosis or treatment purposes;
medical equipment rental.
Surgical and medical apparatus and instruments; medical
implants; implants for neurostimulation; apparatus for
stimulating nerves; electrical neurostimulators; medical
devices for the diagnosis and treatment of headaches and
related disorders, as well as component parts thereof;
electrostimulation devices for treatment of headache and
related disorders, i.e. implantable muscle or nerve
stimulators consisting of artificial materials, and devices
for implanting stimulators; medical devices for activating
implantable stimulators; medical devices for wireless
activation of implantable stimulators; medical devices with
rechargeable batteries for implantable stimulator
activation; medical devices, namely, external stimulators
for implantable stimulator activation; patient screening
kits for diagnosis of headache and related disorders,
consisting of medical devices for diagnosis of headache and
related disorders, electronic data recorders for recording
information collected in the diagnosis of headache and
related disorders, and computer software for management of
data for use with medical devices for diagnosis of headache
and related disorders, all sold as a set; electrical
stimulation systems for medical use.
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Appareils et instruments chirurgicaux et médicaux nommément, générateurs d'impulsions pour la neurostimulation; implants médicaux nommément implants constitués de matériaux artificiels; implants pour la neurostimulation, nommément implants constitués de matériaux artificiels; appareils pour la stimulation des nerfs, nommément, stimulateurs électroniques de nerfs à des fins médicales ; neurostimulateurs électriques; dispositifs médicaux pour le diagnostic et le traitement des céphalées et troubles neurologiques connexes, sous forme d'électrodes jetables; appareils d'électrostimulation pour le traitement des céphalées et troubles connexes, à savoir stimulateurs musculaires ou nerveux implantables se composant de matériaux artificiels, et dispositifs pour l'implant de stimulateurs; dispositifs médicaux pour l'activation de stimulateurs nerveux implantables; dispositifs médicaux pour l'activation sans fil de stimulateurs nerveux implantables; dispositifs médicaux à batteries rechargeables pour l'activation de stimulateurs nerveux implantables; dispositifs médicaux, à savoir stimulateurs nerveux externes pour l'activation de stimulateurs nerveux implantables; trousses de dépistage de patients pour le diagnostic des céphalées et des troubles neurologiques connexes, se composant de dispositifs médicaux pour le diagnostic des céphalées et des troubles neurologiques connexes, d'enregistreurs de données électroniques pour l'enregistrement d'informations collectées dans le diagnostic des céphalées et des troubles neurologiques connexes, et de logiciels informatiques pour la gestion de données à utiliser avec des dispositifs médicaux pour le diagnostic des céphalées et des troubles neurologiques connexes; systèmes de stimulation électrique à usage médical comprenant des stimulateurs électriques de nerfs; aiguilles d'injection à usage médical pour l'injection de blocs nerveux chez les patients souffrant de céphalées et troubles neurologiques connexes; instruments d'injection à usage nasal utilisant le guidage et les informations IRM/CT pour les injections dans les structures nerveuses de la tête et du cerveau; aiguille d'injection à usage médical pour produits pharmaceutiques. (1) Services scientifiques et services de recherche dans le domaine des équipements médicaux destinés au traitement des céphalées et troubles connexes; services d'assistance technique sous la forme de diagnostic technique en rapport avec le dysfonctionnement des équipements médicaux destinés au traitement des céphalées et troubles connexes; recherches médicales; conception et développement d'appareils de diagnostic médical destinés au traitement des céphalées et troubles connexes; conception et développement de technologies médicales destinées au traitement des céphalées et troubles connexes.
(2) Services médicaux nommément pour le traitement des maux de tête et des troubles neurologiques connexes; traitements médicaux, nommément services médicaux pour le traitement des céphalées et des troubles neurologiques connexes; Thérapie par neurostimulation pour le traitement des céphalées et troubles neurologiques connexes; services médicaux, à savoir diagnostic et traitement des céphalées et troubles neurologiques connexes; services de conseillers médicaux dans les domaines des céphalées et troubles neurologiques connexes, fournis à des patients et médecins; fourniture d'informations médicales dans le domaine des céphalées et troubles neurologiques connexes; conduite d'études sur les céphalées et troubles neurologiques connexes, à des fins de diagnostic médical ou de traitement; location d'équipements médicaux.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Services médicaux nommément pour le traitement des maux de tête et des troubles neurologiques connexes; traitements médicaux, nommément services médicaux pour le traitement des céphalées et des troubles neurologiques connexes; Thérapie par neurostimulation pour le traitement des céphalées et troubles neurologiques connexes; services médicaux, à savoir diagnostic et traitement des céphalées et troubles neurologiques connexes; services de conseillers médicaux dans les domaines des céphalées et troubles neurologiques connexes, fournis à des patients et médecins; mise à disposition d'informations médicales dans le domaine des céphalées et troubles neurologiques connexes; services médicaux nommément, services de diagnostic médical et traitement médical basés sur les résultats des études concernant les céphalées et troubles neurologiques connexes.
Surgical and medical apparatus and instruments, namely, pulse generators for neurostimulation; medical implants, namely, implants consisting of artificial materials; implants for neurostimulation, namely, implants consisting of artificial materials; apparatus for stimulating nerves, namely, electronic nerve stimulators for medical purposes; electrical neurostimulators, namely, nerve stimulators for medical purposes; medical devices for the diagnosis and treatment of headaches and related neuro disorders in the nature of disposable electrodes; medical electrostimulation devices for treatment of headache and related neuro disorders, namely, implantable muscle or nerve stimulators consisting of artificial materials, and medical devices for implanting nerve stimulators; medical devices for activating implantable nerve stimulators; medical devices for wireless activation of implantable nerve stimulators; medical devices with rechargeable batteries for implantable nerve stimulator activation; medical devices, namely, external nerve stimulators for implantable nerve stimulator activation; patient screening kits for diagnosis of headache and related neuro disorders, consisting of medical devices for diagnosis of headache and related neuro disorders, electronic data recorders for recording medical information collected in the diagnosis of headache and related neuro disorders, and recorded computer software for database management of medical data for use with medical devices for diagnosis of headache and related neuro disorders, all sold as a set; electrical stimulation systems for medical use comprising electrical nerve stimulators
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical services; medical treatments, namely, medical services for the treatment of headaches and related neuro disorders; providing neurostimulation therapy for treating headaches and related neuro disorders; medical services, namely, diagnosis and treatment of headaches and related neuro disorders; medical consultancy in the fields of headaches and related neuro disorders, provided to patients and doctors; providing medical information in the field of headaches and related neuro disorders; medical services, namely, medical diagnostic services and medical treatment based on study results regarding headaches and related neuro disorders
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Surgical and medical apparatus and instruments, namely, pulse generators for neurostimulation ; medical implants, namely, implants consisting of artificial materials; implants for neurostimulation, namely, implants consisting of artificial materials; apparatus for stimulating nerves, namely, electronic nerve stimulators for medical purposes; electrical neurostimulators, namely, nerve stimulators for medical purposes; medical devices for the diagnosis and treatment of headaches and related neuro disorders in the nature of disposable electrodes; medical electrostimulation devices for treatment of headache and related neuro disorders, namely implantable muscle or nerve stimulators consisting of artificial materials, and medical devices for implanting nerve stimulators; medical devices for activating implantable nerve stimulators; medical devices for wireless activation of implantable nerve stimulators; medical devices with rechargeable batteries for implantable nerve stimulator activation; medical devices, namely, external nerve stimulators for implantable nerve stimulator activation; patient screening kits for diagnosis of headache and related neuro disorders, consisting of medical devices for diagnosis of headache and related neuro disorders, electronic data recorders for recording medical information collected in the diagnosis of headache and related neuro disorders, and recorded computer software for database management of medical data for use with medical devices for diagnosis of headache and related neuro disorders, all sold as a set; electrical stimulation systems for medical use comprising electrical nerve stimulators Scientific research services and medical research services in the field of medical equipment for the treatment of headaches and related neuro disorders; technical support services, namely, troubleshooting in the nature of diagnosing problems with medical equipment used in the treatment of headaches and related neuro disorders; medical research; designing and developing medical diagnosis apparatus for the treatment of headaches and related neuro disorders; designing and developing medical technologies in the nature of medical devices for the treatment of headaches and related neuro disorders, Medical services; medical treatments, namely, medical services for the treatment of headaches and related neuro disorders; providing neurostimulation therapy for treating headaches and related neuro disorders; medical services, namely, diagnosis and treatment of headaches and related neuro disorders; medical consultancy in the fields of headaches and related neuro disorders, provided to patients and doctors; providing medical information in the field of headaches and related neuro disorders; conducting studies on headaches and related neuro disorders, for medical diagnosis or treatment purposes; medical equipment rental
16.
SYSTEM, IMPLANT UNIT AND METHOD FOR THE TREATMENT OF HEAD AND FACIAL PAIN
Disclosed herein is a neurostimulation system for treating head pain, the system comprising: an implant unit configured for implantation inside a subject's (700) body; an external unit configured for a location external to the subject's (700) body; and a charging and programming unit; wherein the external unit comprises: a processor; a power source (220); and a primary transmission unit (230) in electrical communication with the power source (220) and the processor; wherein the implant unit comprises: at least one lead (310); at least one pair of modulation electrodes (320) attached to the at least one lead (310); and a secondary transmission unit (330) in electrical communication with the at least one lead (310); and wherein the processor is configured to establish a coupling between the primary transmission unit (230) and the secondary transmission unit (330) and to transmit power from the power source (220) to the implant unit via said coupling. According to another aspect of the present disclosure, an implant unit for use in a neurostimulation system is described, wherein the implant unit is configured for implantation inside a subject's (700) body through an incision (600) subject's (700) skin, and wherein the implant unit is further configured for implantation inside the subject's (700) body through a tunnel (610). According to yet another aspect of the disclosure, a method for electrical stimulation of neuromuscular tissue using a neurostimulation system is described herewith, the method comprising: generating an electrical stimulation pattern with an external unit, the electrical stimulation pattern comprising at least one modulation signal; delivering the electrical stimulation pattern to an implant unit located inside a subject's (700) body; adjusting the electrical stimulation pattern, wherein adjusting the electrical stimulation pattern comprises increasing or decreasing a voltage, a current amplitude, a pulse frequency and/or a pulse width of the electrical stimulation pattern. Such a method may be valuable, for example, in pain management, where the propagation of pain signals is undesired.
Disclosed herein is a neurostimulation system for treating head pain, the system comprising: an implant unit configured for implantation inside a subject's (700) body; an external unit configured for a location external to the subject's (700) body; and a charging and programming unit; wherein the external unit comprises: a processor; a power source (220); and a primary transmission unit (230) in electrical communication with the power source (220) and the processor; wherein the implant unit comprises: at least one lead (310); at least one pair of modulation electrodes (320) attached to the at least one lead (310); and a secondary transmission unit (330) in electrical communication with the at least one lead (310); and wherein the processor is configured to establish a coupling between the primary transmission unit (230) and the secondary transmission unit (330) and to transmit power from the power source (220) to the implant unit via said coupling. According to another aspect of the present disclosure, an implant unit for use in a neurostimulation system is described, wherein the implant unit is configured for implantation inside a subject's (700) body through an incision (600) subject's (700) skin, and wherein the implant unit is further configured for implantation inside the subject's (700) body through a tunnel (610). According to yet another aspect of the disclosure, a method for electrical stimulation of neuromuscular tissue using a neurostimulation system is described herewith, the method comprising: generating an electrical stimulation pattern with an external unit, the electrical stimulation pattern comprising at least one modulation signal; delivering the electrical stimulation pattern to an implant unit located inside a subject's (700) body; adjusting the electrical stimulation pattern, wherein adjusting the electrical stimulation pattern comprises increasing or decreasing a voltage, a current amplitude, a pulse frequency and/or a pulse width of the electrical stimulation pattern. Such a method may be valuable, for example, in pain management, where the propagation of pain signals is undesired.
An implantable stimulator is provided for stimulating muscles or nerves. The implantable stimulator may comprise an array of electrodes for electrically stimulating at least one of a nerve or a muscle of a subject, and at least one processing device. The at least one processing device may be configured to detect, based on signals received from the array of electrodes, a measurement of an electromyography signal; dynamically select one or more electrodes within the array of electrodes to stimulate the nerve or muscle, the one or more electrodes being selected based on the measurement in order to stimulate a desired area of the nerve or muscle; and receive, from an external device, power used both to activate the selected electrodes and to stimulate the nerve or muscle
Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to be received by and retained by a receiver associated with a housing configured for mounting on the carrier.
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H02J 5/00 - Circuit arrangements for transfer of electric power between ac networks and dc networks
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
20.
Devices and methods for low current neural modulation
A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.
A delivery system is disclosed having an implant retainer configured to releasably hold an implant unit and maintain the implant unit in a fixation location relative to target tissue in a subject's body during an implantation procedure. A first suture guide portion may be disposed on a first side of the implant retainer and configured to guide a suture needle during the implantation procedure. A second suture guide portion may be disposed on a second side of the implant retainer, opposite the first side, and configured to guide the suture needle after the suture needle exits the first suture guide portion.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
H02J 50/05 - Circuit arrangements or systems for wireless supply or distribution of electric power using capacitive coupling
22.
Apparatus and methods for feedback-based nerve modulation
A device according to some embodiments may include a housing configured for location external to a body of a subject. The device may also include at least one processor associated with the housing and configured to communicate with a circuit implanted in the subject within proximity to a tongue of the subject, wherein the circuit is in electrical communication with at least one electrode, receive a physiological signal from the subject via the circuit, and send a control signal to the implanted circuit in response to the physiological signal, wherein the control signal is predetermined to activate neuromuscular tissue within the tongue.
An implant unit according to some embodiments may include a flexible carrier, at least one pair of modulation electrodes on the flexible carrier, and at least one implantable circuit in electrical communication with the at least one pair of modulation electrodes. The at least one pair of modulation electrodes and the at least one circuit may be configured for implantation through derma on an underside of a subject's chin and for location proximate to terminal fibers of the medial branch of the subject's hypoglossal nerve, such that an electric field extending from the at least one pair of modulation electrodes can modulate one or more of the terminal fibers of the medial branch of the hypoglossal nerve.
A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
Systems and methods for hypertension control via energy delivery to one or more nerves affecting blood pressure are provided. Systems may include implantable devices configured for non-contacting neuromodulation. Implantable devices may be configured for intravascular implantation. Systems may also include external devices configured to communicated with implantable neuromodulation devices, Additional systems may include non-implantable devices for delivering modulation energy and ablation energy to one or more nerves affecting blood pressure.
A device according to some embodiments may include an implantable flexible carrier and a pair of electrodes located on the carrier. The electrodes may be spaced from each other by a distance greater than 3 mm, and may be configured to cause, when supplied with an electrical signal, a unidirectional electric field sufficient to modulate at least one nerve.
A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.
An implant unit according to some embodiments may include a flexible carrier, at least one pair of modulation electrodes on the flexible carrier, and at least one implantable circuit in electrical communication with the at least one pair of modulation electrodes. The at least one pair of modulation electrodes and the at least one circuit may be configured for implantation through derma on an underside of a subject's chin and for location proximate to terminal fibers of the medial branch of the subject's hypoglossal nerve, such that an electric field extending from the at least one pair of modulation electrodes can modulate one or more of the terminal fibers of the medial branch of the hypoglossal nerve.
A sleep apnea treatment device may include a flexible carrier configured to be implanted in a body of a subject. The device may also include at least one electrode disposed on the flexible carrier, the at least one electrode being configured to modulate nerve fibers of the subject. A flexible antenna may be disposed on the flexible carrier, the flexible antenna electrically connected to the at least one electrode in a manner permitting at least some energy received by the flexible antenna to be transferred to the at least one electrode. The flexible antenna may include: at least a first conductive trace arranged on a first side of the flexible carrier, the at least a first conductive trace defining at least a first elongated space between portions thereof; and at least a second conductive trace arranged on a second side of the flexible carrier, the at least a second conductive trace defining at least a second elongated space between portions thereof, wherein the at least a first conductive trace is at least partially offset from the at least a second conductive trace such that portions of the first conductive trace overly the at least a second elongated space and wherein portions of the second conductive trace underlay the at least a first elongated space.
A61N 1/372 - Arrangements in connection with the implantation of stimulators
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
An implant unit may include a substrate and an implantable circuit arranged on the substrate. An encapsulation structure may be disposed over at least a portion of the substrate and at least a portion of the implantable circuit, the encapsulation structure including a parylene layer and a silicon layer disposed over the parylene layer.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/372 - Arrangements in connection with the implantation of stimulators
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
31.
Insert tool for selectively powering an implant unit
An implant unit delivery tool is disclosed having an implant tool and an implant activator. The implant tool may be configured to retain an implant unit during an implantation procedure in which the implant unit is fixated to tissue. The implant activator may be associated with the implant tool. Additionally, the implant activator may be configured to selectively transfer power to the implant unit during the implantation procedure to cause modulation of at least one nerve in the body of a subject prior to final fixation of the implant unit to the tissue.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
32.
Apparatus and methods for feedback-based nerve modulation
A device according to some embodiments may include a housing configured for location external to a body of a subject. The device may also include at least one processor associated with the housing and configured to communicate with a circuit implanted in the subject within proximity to a tongue of the subject, wherein the circuit is in electrical communication with at least one electrode, receive a physiological signal from the subject via the circuit, and send a control signal to the implanted circuit in response to the physiological signal, wherein the control signal is predetermined to activate neuromuscular tissue within the tongue.
A device for powering an implant within a body of a subject from a location external to the subject, wherein the implant requires a threshold rate of power increase in order to operate in at least one mode, may include an antenna configured to wirelessly transmit energy to the implant. The device may also include a power storage unit configured to store energy from a power source incapable of delivering the threshold rate of power increase to enable the implant unit to operate in the at least one mode and a power release unit configured to release a pulse of energy from the power storage unit to the antenna after the power storage unit collects an amount of energy sufficient to enable the implant unit to operate in the at least one mode.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/372 - Arrangements in connection with the implantation of stimulators
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
A device according to some embodiments may include an implant unit which may include a flexible carrier, an antenna arranged on the flexible carrier, at least one pair of modulation electrodes on the flexible carrier, at least one implantable circuit electrically connected to the at least one pair of modulation electrodes and the antenna; and at least one pair of suture holes passing through the flexible carrier. The at least one pair of suture holes may be arranged on the flexible carrier such that the flexible carrier may be configured to conform to tissue in a subject's body, and such that each suture hole of the at least one pair of suture holes may be positioned to allow suturing to tissue adjacent to the suture holes.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/372 - Arrangements in connection with the implantation of stimulators
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
A device according to some embodiments may include an implantable flexible carrier and a pair of electrodes located on the carrier. The electrodes may be spaced from each other by a distance greater than 3 mm, and may be configured to cause, when supplied with an electrical signal, a unidirectional electric field sufficient to modulate at least one nerve.
A device according to some embodiments may include an implantable flexible carrier and a pair of electrodes located on the carrier. The electrodes may be spaced from each other by a distance greater than 3 mm, and may be configured to cause, when supplied with an electrical signal, a unidirectional electric field sufficient to modulate at least one nerve.
A device for delivering energy as a function of degree coupling may include an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The device may further include a primary antenna associated with the at least one processor. The processor may be configured to determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
A device according to some embodiments may include a housing configured for location external to a body of a subject. The device may also include at least one processor associated with the housing and configured to communicate with a circuit implanted in the subject within proximity to a tongue of the subject, wherein the circuit is in electrical communication with at least one electrode, receive a physiological signal from the subject via the circuit, and send a control signal to the implanted circuit in response to the physiological signal, wherein the control signal is predetermined to activate neuromuscular tissue within the tongue.
A device according to some embodiments may include a housing configured for location external to a body of a subject. The device may also include at least one processor associated with the housing and configured for electrical communication with a power source, and an antenna associated with the at least one processor. The at least one processor may be configured to communicate with an implant circuit located within the body of the subject, cause the implant circuit to receive power in a first power mode and in a second power mode, wherein a first level of power delivered in the first power mode is less than a second level of power delivered in the second power mode, and wherein during a therapy period, power delivery in the first mode occurs over a total time that is greater than about 50% of the therapy period.
A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.
An implant unit according to some embodiments may include a flexible carrier, at least one pair of modulation electrodes on the flexible carrier, and at least one implantable circuit in electrical communication with the at least one pair of modulation electrodes. The at least one pair of modulation electrodes and the at least one circuit may be configured for implantation through derma on an underside of a subject's chin and for location proximate to terminal fibers of the medial branch of the subject's hypoglossal nerve, such that an electric field extending from the at least one pair of modulation electrodes can modulate one or more of the terminal fibers of the medial branch of the hypoglossal nerve.
An implant unit configured for implantation into a body of a subject may include an antenna configured to receive a signal. The implant unit may also include at least one pair of modulation electrodes configured to be implanted into the body of the subject in the vicinity of at least one nerve to be modulated, the at least one pair of modulation electrodes being configured to receive an applied electric signal in response to the signal received by the antenna and generate an electrical field to modulate the at least one nerve from a position where the at least one pair of modulation electrodes does not contact the at least one nerve.
A device for powering an implant within a body of a subject from a location external to the subject, wherein the implant requires a threshold rate of power increase in order to operate in at least one mode, may include an antenna configured to wirelessly transmit energy to the implant. The device may also include a power storage unit configured to store energy from a power source incapable of delivering the threshold rate of power increase to enable the implant unit to operate in the at least one mode and a power release unit configured to release a pulse of energy from the power storage unit to the antenna after the power storage unit collects an amount of energy sufficient to enable the implant unit to operate in the at least one mode.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
44.
Apparatus and methods for modulating nerves using parallel electric fields
A device may include at least one pair of modulation electrodes configured for implantation in the vicinity of a nerve to be modulated such that the electrodes are spaced apart from one another along a longitudinal direction of the nerve to be modulated. The electrodes may be further configured to facilitate an electric field in response to an applied electric signal, the electric field including field lines extending in the longitudinal direction of the nerve to be modulated. The device may further include at least one circuit in electrical communication with the at least one pair of modulation electrodes and being configured to cause application of the electric signal applied at the at least one pair of modulation electrodes.
An implantable stimulator for stimulating muscles or nerves, including, an array of electrodes for electrically stimulating muscles or nerves, a controller for controlling the activity of the electrodes, and wherein the controller is adapted to dynamically select the electrodes that are used to participate in stimulating the muscles or nerves.
An implantable stimulator for stimulating muscles or nerves, including, an array of electrodes for electrically stimulating muscles or nerves, a controller for controlling the activity of the electrodes, and wherein the controller is adapted to dynamically select the electrodes that are used to participate in stimulating the muscles or nerves.
