Abstract

The invention relates to the use of oligo(ethylene oxide) dendritic molecules for stabilizing fluorocarbon-based nanoemulsions, to fluorocarbon-based nanoemulsions comprising such dendritic molecules and to their uses for biomedical applications, in particular as contrast agents, drug carrier or oxygenating agent.

IPC Classes  ?

• A61K 49/22 - Echographic preparationsUltrasound imaging preparations

Abstract

The present invention relates to polyfunctional organic dendritic molecules derived from alkyl phosphonates or esters, to a process for preparing the same and to the use thereof, in particular as drug carriers or contrast agents.

IPC Classes  ?

• C07F 9/40 - Esters thereof
• A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
• A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
• A61K 49/00 - Preparations for testing in vivo
• C07C 235/52 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups

Abstract

The invention relates to the use of oligo(ethylene oxide) dendritic molecules for stabilizing fluorocarbon-based nanoemulsions, to fluorocarbon- based nanoemulsions comprising such dendritic molecules and to their uses for biomedical applications, in particular as contrast agents, drug carrier or oxygenating agent.

IPC Classes  ?

• A61K 49/22 - Echographic preparationsUltrasound imaging preparations

Abstract

The present invention relates to polyfunctional organic dendritic molecules derived from alkyl phosphonates or esters, to a process for preparing the same and to the use thereof, in particular as drug carriers or contrast agents.

IPC Classes  ?

• C08G 83/00 - Macromolecular compounds not provided for in groups
• A61K 49/18 - Nuclear magnetic resonance [NMR] contrast preparationsMagnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
• C07F 9/38 - Phosphonic acids [R—P(:O)(OH)2]Thiophosphonic acids
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 49/00 - Preparations for testing in vivo
• C07C 235/48 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
• C07F 9/40 - Esters thereof
• A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient

Abstract

The present invention relates to polyfunctional organic dendritic molecules derived from alkyl phosphonates or esters, to a process for preparing the same and to the use thereof, in particular as drug carriers or contrast agents.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/00 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient
• A61K 49/00 - Preparations for testing in vivo
• A61K 49/18 - Nuclear magnetic resonance [NMR] contrast preparationsMagnetic resonance imaging [MRI] contrast preparations characterised by a special physical form, e.g. emulsions, microcapsules, liposomes
• C07C 235/48 - Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings and singly-bound oxygen atoms bound to the same carbon skeleton with carbon atoms of carboxamide groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
• C07F 9/38 - Phosphonic acids [R—P(:O)(OH)2]Thiophosphonic acids
• C07F 9/40 - Esters thereof
• C08G 83/00 - Macromolecular compounds not provided for in groups

Abstract

The invention relates to the use of oligo(ethylene oxide) dendritic molecules for stabilizing fluorocarbon-based nanoemulsions, to fluorocarbon- based nanoemulsions comprising such dendritic molecules and to their uses for biomedical applications, in particular as contrast agents, drug carrier or oxygenating agent.

IPC Classes  ?

• A61K 49/22 - Echographic preparationsUltrasound imaging preparations

Goods & Services

Chemical products for use in industry and science; chemical reagents other than for medical or veterinary use. Pharmaceutical products; chemical preparations for pharmaceutical use. Scientific research.

Goods & Services

Pharmaceutical products; chemical preparations for pharmaceutical use. Scientific research; research and development of new products for third parties. Hospital services.

Goods & Services

(1) Produits pharmaceutiques pour le diagnostic et le traitement du cancer et des maladies neurodégénératives; produits pharmaceutiques destinés à régénérer des tissus ; produits pharmaceutiques utilisés en thérapie cellulaire; préparations chimiques à usage pharmaceutique, nommément nanoparticules magnétiques (1) Recherches scientifiques dans le domaine de l'oncologie, des maladies neurodégénératives, de la régénération de tissus et des thérapies cellulaires; recherche et développement de nouveaux produits pour des tiers (2) Services hospitaliers, nommément consultation en soins de santé dans le domaine de l'oncologie, des maladies neurodégénératives, de la régénération de tissues et des thérapies cellulaires

Goods & Services

Pharmaceutical preparations for the diagnosis and treatment of cancer; chemical preparations for pharmaceutical use, namely, for the diagnosis and treatment of cancer Scientific research; research and development of new products for third parties Hospital services

Goods & Services

(1) Produits chimiques destinés à l'industrie et aux sciences, nommément ingrédients chimiques actifs pour la fabrication de produits pharmaceutiques (2) Produits pharmaceutiques pour le diagnostic et le traitement du cancer et des maladies neurodégénératives; produits pharmaceutiques destinés à régénérer des tissus ; produits pharmaceutiques utilisés en thérapie cellulaire; préparations chimiques à usage pharmaceutique, nommément nanoparticules magnétiques (1) Recherches scientifiques dans le domaine de l'oncologie, des maladies neurodégénératives, de la régénération de tissus et des thérapies cellulaires

Goods & Services

Chemicals for use in industry and science; chemical reagents other than for medical or veterinary use Pharmaceutical products for the diagnosis and treatment of cancer; chemical preparations for pharmaceutical use, namely, for the diagnosis and treatment of cancer Scientific research