The present invention provides a method for determining whether a mature cotton fiber includes Giza 94 (G94) variety of G. barbadense. The method comprises providing a mature cotton fiber from a manufactured article; extracting DNA from the mature cotton fiber; amplifying a portion of said DNA with a PCR-based technique using a primer set comprising SEQ ID NO: 1 and SEQ ID NO: 2, thereby producing one or more amplicons, generating a variable amplicon length polymorphism profile (VALP) from the amplicons, and comparing the generated VALP with a G94 variable amplicon length polymorphism profile, thereby determining whether the mature cotton fiber incudes G94.
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
3.
Methods and Systems of Producing Single Stranded DNA via PCR Using Biotin-Labeled Primers
The present invention provides methods of producing single-stranded DNA (ssDNA) from a double-stranded DNA (dsDNA) template. The method includes selecting either the (+)-strand or the (−)-strand of a dsDNA template as a target ssDNA, wherein if the target ssDNA is the (+)-strand of the dsDNA template, a biotin label is added onto the reverse primer, and wherein if the target ssDNA is the (−)-strand of the dsDNA template, a biotin label is added onto the forward primer. Next PCR is performed to produce biotinylated dsDNA fragments. Once the PCR is terminated, the biotinylated dsDNA fragments are purified. Next the target ssDNA is separated from the biotinylated dsDNA by immobilizing the biotinylated dsDNA onto a surface and precipitating the target ssDNA.
01 - Chemical and biological materials for industrial, scientific and agricultural use
05 - Pharmaceutical, veterinary and sanitary products
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
Goods & Services
mRNA production platform and in vivo transcription, namely, biochemicals for in vitro and in vivo scientific use; Biological preparations for use in industry and science; nucleic acid for laboratory use Nucleic acid sequences for medical purposes; nucleic acid sequences and chemical reagents for medical and veterinary purposes; Biological preparations for the treatment of cancer Custom manufacturing of DNA expression vectors, namely plasmids, viruses and biological constructs designed for gene expression in cells, for others; custom biological manufacturing services for others, namely, manufacturing of pharmaceuticals using biological organisms in the manufacturing process, namely, nucleic acids, DNA, RNA, and mRNA; custom manufacture of pharmaceuticals using biological organisms in the manufacturing process, namely, DNA and mRNA for others as components of in vitro diagnostic tests and for preclinical nucleic acid-based drug development in the fields of adoptive cell therapies as CAR T and TCR T therapies, anti-viral and cancer DNA vaccines, RNA therapies, clustered regularly interspaced short palindromic repeats (CRISPR) based therapies, and gene therapies Scientific research; biotechnology research and development; biological research; biomedical research; research and development services in the field of DNA based medications and therapies; DNA expression vector design and development for others; biotech and clinical research and development of DNA based medications and therapies
5.
SYSTEM AND METHOD FOR ON-SITE AUTHENTICATION OF NUCLEIC ACID TAGGANTS USING NUCLEIC ACID LATERAL FLOW DEVICE
A system and method for interrogating objects containing a nucleic acid taggant including a sample collection device for obtaining a sample containing a nucleic acid taggant from an object. The at least one taggent includes at least one predetermined nucleic acid sequence. A reagent contacts the sample. A polymerase chain reaction (PCR) device for device for receiving the sample and amplifying the at least one nucleic acid sequence contained in the sample to produce a PCR sample solution. A Nucleic Acid Lateral Flow (NALF) device has a sample receiving end for receiving the PCR sample solution and having an indication end. The indication end includes a first test area and at least one control area. The first test area provides a visual indication upon the detection of a first predetermined nucleic acid sequence carried in the PCR sample solution.
The present invention provides a method for determining whether a mature cotton fiber includes Giza 94 (G94) variety of G. barbadense. The method comprises providing a mature cotton fiber from a manufactured article; extracting DNA from the mature cotton fiber; amplifying a portion of said DNA with a PCR-based technique using a primer set comprising SEQ ID NO: 1 and SEQ ID NO: 2, thereby producing one or more amplicons, generating a variable amplicon length polymorphism profile (VALP) from the amplicons, and comparing the generated VALP with a G94 variable amplicon length polymorphism profile, thereby determining whether the mature cotton fiber incudes G94.
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
7.
METHODS FOR GENETIC ANALYSIS OF TEXTILES COMPRISING G. BARBADENSE
The present invention provides a method for determining whether a mature cotton fiber includes Giza 94 (G94) variety of G. barbadense. The method comprises providing a mature cotton fiber from a manufactured article; extracting DNA from the mature cotton fiber; amplifying a portion of said DNA with a PCR-based technique using a primer set comprising SEQ ID NO: 1 and SEQ ID NO: 2, thereby producing one or more amplicons, generating a variable amplicon length polymorphism profile (VALP) from the amplicons, and comparing the generated VALP with a G94 variable amplicon length polymorphism profile, thereby determining whether the mature cotton fiber incudes G94.
C12Q 1/6895 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12Q 1/6806 - Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
The invention relates to methods of treating diseases comprising administering to a subject a composition comprising the recombinant adeno-associated virus (rAAV). The rAAV is produced by a method comprising: obtaining a template DNA sequence containing a [ITR-cargo-ITR] DNA sequence motif; designing a PCR primer pair such that the 3′ terminus of both the forward and reverse PCR primers overlap only about the last 2-8 bases of the A/A′ ITR sequences and the 5′ terminus of both the forward and reverse PCR primers extend into about 20-35 bases of the flanking sequences; performing PCR with cycling parameters comprising a combined annealing/extension step at a temperature greater than 70° C., thereby producing a plurality of amplicon polynucleotides containing the desired [ITR-cargo-ITR] DNA sequence motif; transfecting the amplicon polynucleotides containing the desired [ITR-cargo-ITR] DNA sequence motif into a packaging cell line; and purifying the lysed cells to collect a quantity of rAAV.
C12Q 1/6848 - Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
C12N 7/00 - Viruses, e.g. bacteriophagesCompositions thereofPreparation or purification thereof
C12Q 1/6883 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
9.
ENGINEERED LYMPHOCYTE COMPOSITIONS, METHODS AND SYSTEMS
The present inventions provides systems and methods to manufacture genetically modified lymphocyte cells via the use of linear DNA expression amplicons, and uses of such genetically modified lymphocyte cells to treat disease. The present invention also provides for the composition of genetically modified lymphocyte cells.
The present invention relates generally to PCR-based in vitro diagnostics and methods of treatment for SARS-CoV-2, the virus that causes COVID- 19, and more specifically, to compositions and methods for the detection of wildtype and variants of SARS-CoV-2 in a patient specimen and methods of treating SARS-CoV-2 based on said detection.
C12Q 1/6827 - Hybridisation assays for detection of mutation or polymorphism
C12Q 1/70 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving virus or bacteriophage
The present invention relates to systems and methods to produce recombinant adeno-associated virus (rAAV) utilizing one or more DNA constructs manufactured via polymerase chain reaction (PCR).
The present invention relates generally to a system and method of tracking leather raw materials through the supply chain to create a source verifiable finished leather product through one or more applications of DNA taggants during the leather manufacturing process and the subsequent authentication of said DNA taggants.
B05D 7/12 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to leather
B05D 5/00 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
The present invention relates generally to a system and method of tracking leather raw materials through the supply chain to create a source verifiable finished leather product through one or more applications of DNA taggants during the leather manufacturing process and the subsequent authentication of said DNA taggants.
05 - Pharmaceutical, veterinary and sanitary products
42 - Scientific, technological and industrial services, research and design
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical diagnostic assays for testing for Covid-19/SARS-CoV-2; Medical diagmostic assays for testing for viruses Platform as a service (PaaS) featuring computer software platforms to review and analyze COVID-19/ SARS-CoV-2 medical diagnostic surveillance testing results and to track, manage, and analyze data related to employee, customer, and passenger health status Medical diagmostic testing, namely, Covid-19/SARS-CoV-2 Surveillance testing; viral surveillance testing; Medical diagmostic testing consulting services in the fields of COVID-19/SARS-CoV-2 surveillance testing; Medical diagmostic testing consulting services in the fields of viral surveillance testing
Methods for marking cellulosic products, including cellulosic fibers such as lyocell and cellulosic films, including methods for marking such products with a detectable nucleic acid marker to identify and validate the origin or authenticity of the products or items manufactured using such products. Detectably-marked cellulosic products marked with nucleic acid markers for authentication, validation and tracking are also provided.
The present inventions provides systems and methods to manufacture genetically modified lymphocyte cells via the use of linear DNA expression amplicons, and uses of such genetically modified lymphocyte cells to treat disease. The present invention also provides for the composition of genetically modified lymphocyte cells.
The present inventions provides systems and methods to manufacture genetically modified lymphocyte cells via the use of linear DNA expression amplicons, and uses of such genetically modified lymphocyte cells to treat disease. The present invention also provides for the composition of genetically modified lymphocyte cells.
The present inventions provides systems and methods to manufacture genetically modified lymphocyte cells via the use of linear DNA expression amplicons, and uses of such genetically modified lymphocyte cells to treat disease. The present invention also provides for the composition of genetically modified lymphocyte cells.
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
A61K 39/00 - Medicinal preparations containing antigens or antibodies
C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
The invention provides for a system to track the origin of cannabis products and cannabis derivative products without the need for packaging or labeling through the use of nucleic acid tags. The invention further provides for a method of tracking the origin of cannabis products and cannabis derivative products via the application of nucleic acid tags to cannabis plants.
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12N 15/11 - DNA or RNA fragmentsModified forms thereof
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
C40B 40/06 - Libraries containing nucleotides or polynucleotides, or derivatives thereof
20.
SYSTEMS AND METHODS FOR TRACKING THE ORIGIN OF CANNABIS PRODUCTS AND CANNABIS DERIVATIVE PRODUCTS
The invention provides for a system to track the origin of cannabis products and cannabis derivative products without the need for packaging or labeling through the use of nucleic acid tags. The invention further provides for a method of tracking the origin of cannabis products and cannabis derivative products via the application of nucleic acid tags to cannabis plants.
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12N 15/11 - DNA or RNA fragmentsModified forms thereof
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
C40B 40/06 - Libraries containing nucleotides or polynucleotides, or derivatives thereof
21.
Encrypted optical markers for security applications
Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The encrypted marker may include a DNA taggant.
G07D 7/14 - Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency using chemical means
C40B 20/04 - Identifying library members by means of a tag, label, or other readable or detectable entity associated with the library members, e.g. decoding processes
A composition comprising submicron particles covered by a monolayer of nucleic acid wherein the nucleic acid may be recovered from the submicron particles is claimed. Methods of attaching a nucleic acid to an object for authentication and methods of authenticating an object are also claimed.
A composition comprising submicron particles covered by a monolayer of nucleic acid wherein the nucleic acid may be recovered from the submicron particles is claimed. Methods of attaching a nucleic acid to an object for authentication and methods of authenticating an object are also claimed.
The invention pertains to a traceable fertilizer product marked with a nucleic acid marker. The invention further provides for a method of marking a fertilizer product with a nucleic acid marker. In addition, the invention teaches a method of using a nucleic acid marked fertilizer product to identify and validate the origin or authenticity of said fertilizer product and to perform quantitative analysis on the fertilizer product to determine if said fertilizer product has been adulterated, diluted and/or counterfeited.
A system associated with authentication of an object related to a multi-mode marker using a processing device. The processing device performs operations that include detecting a signal associated with a multi-mode marker related with the object; assigning a digital code based on the detected signal associated with the multi-mode marker; and identifying the object based on the digital code related to authentication of the object. A corresponding method and computer-readable device are also disclosed.
G06K 5/00 - Methods or arrangements for verifying the correctness of markings on a record carrierColumn-detection devices
G06F 17/30 - Information retrieval; Database structures therefor
G06K 7/00 - Methods or arrangements for sensing record carriers
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
G06K 19/07 - Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards with integrated circuit chips
26.
Composition and method of DNA marking elastomeric material
Methods of incorporating coded DNA into elastomeric materials and compositions thereof are claimed. Methods of recovering information from elastomeric materials with coded DNA and authenticating silicone objects with coded DNA are also claimed.
Methods for marking cellulosic products, including cellulosic fibers such as lyocell and cellulosic films, including methods for marking such products with a detectable nucleic acid marker to identify and validate the origin or authenticity of the products or items manufactured using such products. Detectably-marked cellulosic products marked with nucleic acid markers for authentication, validation and tracking are also provided.
B05D 1/02 - Processes for applying liquids or other fluent materials performed by spraying
B05D 5/00 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures
B05D 7/00 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
B41M 5/00 - Duplicating or marking methodsSheet materials for use therein
C09B 62/00 - Reactive dyes, i.e. dyes which form covalent bonds with the substrates or which polymerise with themselves
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
Methods for marking cellulosic products, including cellulosic fibers such as lyocell and cellulosic films, including methods for marking such products with a detectable nucleic acid marker to identify and validate the origin or authenticity of the products or items manufactured using such products. Detectably-marked cellulosic products marked with nucleic acid markers for authentication, validation and tracking are also provided.
42 - Scientific, technological and industrial services, research and design
Goods & Services
DNA analysis services for product authentication and
validation of source; product authentication services using
DNA analysis for verifying and validating the source of a
wide variety of industrial, textile, consumer and military
goods in wholesale and retail supply chains by using
embedded or coated biologics and taggants; DNA analysis
services for source authentication of textiles in the retail
supply chain.
30.
IDENTIFYING MARKED ARTICLES IN THE INTERNATIONAL STREAM OF COMMERCE
A method and system of identifying articles in commerce including tagging a raw material during said raw material's manufacturing process with a unique molecular marker in a home country in which the raw material was produced. The marker identifies home country information. The tagged raw material is transported from the home country to a foreign country. The tagged raw material is processed in the foreign country to generate a processed product. The processed product is transported to the home country. The processed product is analyzing to determine the presence of the marker in the processed product. A determination is made whether the raw material originated in the home country in response to the detection of the marker.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
D04H 1/587 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by applying, incorporating or activating chemical or thermoplastic bonding agents, e.g. adhesives characterised by the bonding agents used
D04H 1/64 - Non-woven fabrics formed wholly or mainly of staple fibres or like relatively short fibres from fleeces or layers composed of fibres without existing or potential cohesive properties by applying, incorporating or activating chemical or thermoplastic bonding agents, e.g. adhesives the bonding agent being applied in wet state, e.g. chemical agents in dispersions or solutions
Towels, beach towels, bath towels, all of the aforementioned goods treated with a molecular and/or biologic taggant for product tracking, authentication and/or validation of source
42 - Scientific, technological and industrial services, research and design
Goods & Services
DNA analysis services for product authentication and validation of source; product authentication services using DNA analysis for verifying and validating the source of a wide variety of industrial, textile, consumer and military goods in wholesale and retail supply chains by using embedded or coated biologics and taggants; DNA analysis services for source authentication of textiles in the retail supply chain.
42 - Scientific, technological and industrial services, research and design
Goods & Services
DNA analysis services for product authentication and validation of source; product authentication services using DNA analysis for verifying and validating the source of a wide variety of industrial, textile, consumer and military goods in wholesale and retail supply chains by using embedded or coated biologics and taggants; DNA analysis services for source authentication of textiles in the retail supply chain
16 - Paper, cardboard and goods made from these materials
Goods & Services
Coatings, namely, paint, varnish and lacquer, applied to goods for use as security markers for identification and authentication of goods; varnish and lacquers applied to goods for use as a security marker; varnish and lacquers containing pro-fluorophore or pro-chromophores which can be made visible only when combined with a reagent; varnish and lacquer for use as an encrypted optical marker Marking ink containing biologics applied to goods for use as a security marker in authentication of objects; marking ink containing biologics for use as an encrypted optical marker in authentication of objects
35.
DNA marking of previously undistinguished items for traceability
The invention provides a method of marking an item with naturally-derived or synthetic non-natural polymeric marker molecules, such as a DNA or Peptide marker in conjunction with optional visible or rapid scan reporters for authenticating or tracking, in which the method includes providing an item for marking, and applying a medium including a DNA marker to the item. The invention further provides methods for stably binding and immobilizing activated deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. Also provided are methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. The invention also provides a method of marking an item with a DNA marker for authenticating or tracking, in which the method includes providing a medium including a DNA marker, and molding the medium including the DNA marker to provide all or part of the item. The DNA marker encodes information unique to the item and/or the model of the item as desired.
G07D 7/14 - Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency using chemical means
42 - Scientific, technological and industrial services, research and design
Goods & Services
DNA analysis services for product authentication and product source verification; product authentication services using DNA analysis for the purpose of verifying the source of a wide variety of industrial, textile, consumer and military goods in wholesale and retail supply chains using embedded or coated biologics and/or taggants; DNA analysis services for the authentication of textiles, pharmaceutical packaging and pharmaceutical tablets or capsules; DNA forensic analysis services
09 - Scientific and electric apparatus and instruments
Goods & Services
Biologically encoded liquid taggants for use in passive labeling and tracing of objects for the purpose of linking marked objects to its owner; biologically encoded liquid marking taggants for the purpose of linking marked objects to its owner; biologically encoded marking inks incorporating nucleic acids for tagging and identifying objects and linking them to its owner; kit comprising a biologically encoded liquid marking substance and a unique DNA identifier for the purpose of linking marked objects to its owner; biologically encoded liquid taggants for application to coatings in the nature of paints for use in source identification of marked objects
01 - Chemical and biological materials for industrial, scientific and agricultural use
42 - Scientific, technological and industrial services, research and design
Goods & Services
Biologics in the nature of nucleic acids and proteins for addition to polymers used in manufacturing of consumer, military and industrial goods and products for authentication, tracking and tracing such goods and products. Laboratory services, namely, authentication for the purposes of validation, tracking and tracing of goods and products as they move through the stream of commerce from initial shipment to delivery, based on embedded or coated biologics on a wide variety of industrial, consumer and military goods and products.
39.
Use of perturbants to facilitate incorporation and recovery of taggants from polymerized coatings
The invention provides methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. Methods for authentication of a taggant marked object are also provided.
Methods for genetic analysis of commodities and raw materials containing DNA, including components and ingredients of dietary supplements are disclosed. The method include extracting DNA from at least one component of a commodity, and the DNA is genetically analyzed by any process used in the art, such as next-generation sequencing methods, to identify at least one DNA sequence. The DNA sequence or a plurality of DNA sequences may then be used authenticate the commodity, or alternatively, to identify and or quantify one or more plant or animal species of the commodity and its components of a commodity or raw material. The one or more identified plant or animal species identified by the methods of the invention as components of a commodity or raw material may be used to verify security of supply chain by tracing a commodity throughout the chain and to compare the analyzed goods to specifications as purchased for compliance, standardization, expected monetary value, and/or accuracy.
The invention provides a method of marking a hydrophobic medium with a nucleic acid marker, the method includes: providing a trialkylammonium salt of the nucleic acid marker, a tetraalkylphosphonium salt of the nucleic acid marker or a tetraarylphosphonium salt of the nucleic acid marker; and incorporating the trialkylammonium salt of the nucleic acid marker, the tetraalkylphosphonium salt of the nucleic acid marker or the tetraarylphosphonium salt of the nucleic acid marker into the hydrophobic medium. The hydrophobic medium can be authenticated after shipping or recovery from the stream of commerce by detecting the nucleic acid marker in a sample of the hydrophobic medium.
Provided is a method of authenticating an active pharmaceutical ingredient (API). The method includes providing an API or an API component and adding a nucleic acid marker having a nucleic acid marker sequence to produce a marked API or a marked API component. At least a portion of the marked API or marked API component is incorporated into a pharmaceutical product. A sample of the pharmaceutical product including the marked API or marked API component is obtained. The sample is subjected to an amplification reaction to produce one or more amplification products that are characteristic of the nucleic acid marker. The presence of the nucleic acid marker is detected in the sample and the authenticity of the API is thereby determined according to whether the pharmaceutical product includes marked API or the marked API component.
Exemplary embodiments of the present invention provide a method for assessing a proportion of one or more cotton species in an article comprising cotton. The method includes providing a sample including cotton fibers from the article comprising cotton. Cotton DNA is extracted from the cotton fibers to provide extracted cotton DNA. The extracted cotton DNA is analyzed to identify a presence of one or more cotton species included in the article comprising cotton. Proportions of the one or more cotton species included in the article comprising cotton are assessed.
A multi-mode reader instrument capable of detecting and determining digital data from a signal from one or more markers, indicia or taggants on an object, the markers, indicia or taggants such as a bar code, a QR code, an RFID, an optical compound, a fluorescent compound, a phosphorescent compound, a DNA taggant, an upconverting phosphor (UCP), a chemical dye, a digitized image, a radioactive compound, an olfactory compound or a thermal attribute of the object is provided. Also, provided is a method and a system for identifying an object, the system includes: a multi-mode reader instrument for detecting data from a signal from one or more markers, indicia or taggants on an object and assignment of digital code for the marker and a database for securing and retrieving information relevant to the item.
G06K 5/00 - Methods or arrangements for verifying the correctness of markings on a record carrierColumn-detection devices
G06F 17/30 - Information retrieval; Database structures therefor
G06K 7/00 - Methods or arrangements for sensing record carriers
G06K 19/06 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code
G06K 19/07 - Record carriers with conductive marks, printed circuits or semiconductor circuit elements, e.g. credit or identity cards with integrated circuit chips
A method of marking fibers, wherein the method includes providing a plurality of fibers; depositing a marker onto at least a portion of the fibers, the depositing being performed with a delivery mechanism comprising one or more outlets; and thereby marking the fibers. Also provided is a device for marking fibers, including a transport system adapted to transport fibers in a direction of a marker delivery apparatus positioned along the transport system; the delivery apparatus includes one or more outlets, adapted to deposit a solution of the marker through the outlets onto at least a portion of the fibers; and thereby marking the fibers. Authentication of a fibrous material using the marking method of the invention followed obtaining a sample of the marked fibers and assaying the sample for the presence of the nucleic acid marker; and thereby determining whether the fibrous material is authentic or counterfeit.
A method of marking fibers, wherein the method includes providing a plurality of fibers; depositing a marker onto at least a portion of the fibers, the depositing being performed with a delivery mechanism comprising one or more outlets; and thereby marking the fibers. Also provided is a device for marking fibers, including a transport system adapted to transport fibers in a direction of a marker delivery apparatus positioned along the transport system; the delivery apparatus includes one or more outlets, adapted to deposit a solution of the marker through the outlets onto at least a portion of the fibers; and thereby marking the fibers. Authentication of a fibrous material using the marking method of the invention followed obtaining a sample of the marked fibers and assaying the sample for the presence of the nucleic acid marker; and thereby determining whether the fibrous material is authentic or counterfeit.
D06M 15/01 - Treating fibres, threads, yarns, fabrics or fibrous goods made from such materials with macromolecular compoundsSuch treatment combined with mechanical treatment with natural macromolecular compounds or derivatives thereof
D06M 16/00 - Biochemical treatment of fibres, threads, yarns, fabrics or fibrous goods made from such materials, e.g. enzymatic
D01G 99/00 - Subject matter not provided for in other groups of this subclass
D01B 9/00 - Other mechanical treatment of natural fibrous or filamentary material to obtain fibres or filaments
D06H 1/00 - Marking textile materialsMarking in combination with metering or inspecting
The invention provides a method for in-field detection of a distinctive marker. The method includes providing a sample from an article of interest and analyzing the sample to detect the presence of the distinctive marker. The analysis is performed using an in-field detection instrument. The in-field detection instrument includes a microsystem configured to perform sample in-answer out analysis and detect the presence of the distinctive marker in the sample.
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
16 - Paper, cardboard and goods made from these materials
42 - Scientific, technological and industrial services, research and design
Goods & Services
Biologics in the nature of proteins for addition to polymers
used in manufacturing of consumer and industrial products
for authentication, tracking and tracing. Marking paints and lacquers containing biologics for use in
authentication of objects; marking coatings in the nature of
paints containing biologics for use in authentication of
objects. Marking ink containing biologics for use in authentication
of objects. Authentication for the purposes of validation, tracking and
tracing of objects using embedded or coated biologics for
protection of goods, products, industrial materials, metals,
currency, and works of art.
01 - Chemical and biological materials for industrial, scientific and agricultural use
02 - Paints, varnishes, lacquers
16 - Paper, cardboard and goods made from these materials
42 - Scientific, technological and industrial services, research and design
Goods & Services
Biologics in the nature of proteins for addition to polymers
used in manufacturing of consumer and industrial products
for authentication, tracking and tracing. Marking paints and lacquers containing biologics for use in
authentication of objects; marking coatings in the nature of
paints containing biologics for use in authentication of
objects. Marking ink containing biologics for use in authentication
of objects. Authentication for the purposes of validation, tracking and
tracing of objects using embedded or coated biologics for
protection of goods, products, industrial materials, metals,
currency, and works of art.
A method of encrypting information includes converting an information sequence represented as a strings of bits into a curvilinear coding system, where each element of the curvilinear coding system corresponds to a sub-sequence of successive same-valued bits, converting said curvilinear coding system into a at least one closed curve, and embedding said at least one closed curve in a 2-dimensional pattern. A method for decrypting information includes extracting at least one closed curve from a digitized 2-dimensional pattern, and converting the at least one closed curve into an information sequence represented as a string of bits.
G06T 9/20 - Contour coding, e.g. using detection of edges
G09C 5/00 - Ciphering or deciphering apparatus or methods not provided for in other groups of this subclass, e.g. involving the concealment or deformation of graphic data such as designs, written or printed messages
A method of encrypting information includes converting an information sequence represented as a strings of bits into a curvilinear coding system, where each element of the curvilinear coding system corresponds to a sub-sequence of successive same-valued bits, converting said curvilinear coding system into a at least one closed curve, and embedding said at least one closed curve in a 2-dimensional pattern. A method for decrypting information includes extracting at least one closed curve from a digitized 2-dimensional pattern, and converting the at least one closed curve into an information sequence represented as a string of bits.
G06F 21/16 - Program or content traceability, e.g. by watermarking
G09C 5/00 - Ciphering or deciphering apparatus or methods not provided for in other groups of this subclass, e.g. involving the concealment or deformation of graphic data such as designs, written or printed messages
H04L 9/32 - Arrangements for secret or secure communicationsNetwork security protocols including means for verifying the identity or authority of a user of the system
52.
Security system and method of marking an inventory item and/or person in the vicinity
A method of marking an inventory item includes providing an activatable smoke generator and a reservoir for holding a smoke fluid and adapted to provide a flow of smoke fluid to the generator. The reservoir contains a smoke fluid including a carrier nucleic acid having a uniquely identifiable sequence, and upon activation of the smoke generator, marker smoke is generated and targeted to flow over the inventory item. The method further includes activating the smoke generator to produce the marker smoke including the carrier nucleic acid so as to cause the marker smoke to flow over the inventory item and thereby to detectably mark the inventory item with carrier nucleic acid. The invention provides methods for stably binding and immobilizing deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. The alkaline conditions are produced by mixing the deoxyribonucleic acid with an alkaline solution having a pH of about 9.0 or higher, and contacting the deoxyribonucleic acid to the substrate. The immobilized DNA can be used as a taggant and can be used in combination with other detectable taggants, such as optical reporters.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
G08B 15/02 - Identifying, scaring or incapacitating burglars, thieves or intruders, e.g. by explosives with smoke, gas, or coloured or odorous powder or liquid
C12Q 1/6876 - Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
B05D 1/00 - Processes for applying liquids or other fluent materials
A method of encrypting information includes converting an information sequence represented as a strings of bits into a curvilinear coding system, where each element of the curvilinear coding system corresponds to a sub-sequence of successive same-valued bits, converting said curvilinear coding system into a at least one closed curve, and embedding said at least one closed curve in a 2-dimensional pattern. A method for decrypting information includes extracting at least one closed curve from a digitized 2-dimensional pattern, and converting the at least one closed curve into an information sequence represented as a string of bits.
G06T 9/20 - Contour coding, e.g. using detection of edges
G09C 5/00 - Ciphering or deciphering apparatus or methods not provided for in other groups of this subclass, e.g. involving the concealment or deformation of graphic data such as designs, written or printed messages
54.
ENCRYPTED OPTICAL MARKERS FOR SECURITY APPLICATIONS
Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The marker can be revealed by exposure of the encrypted marker or a sample thereof to the developer in any suitable form, such as a solution, a slurry, a swab, a solid (such as in granular form), or a gas or a vapor that includes a developer.
Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The marker can be revealed by exposure of the encrypted marker or a sample thereof to the developer in any suitable form, such as a solution, a slurry, a swab, a solid (such as in granular form), or a gas or a vapor that includes a developer.
B29C 65/48 - Joining of preformed partsApparatus therefor using adhesives
G07D 7/14 - Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency using chemical means
56.
ENCRYPED OPTICAL MARKERS FOR SECURITY APPLICATIONS
Encrypted markers that are not readily detectable can be revealed by treatment with a specific reagent used as a developer to reveal a readily detectable physical property of the marker, such as a characteristic fluorescence emission after excitation with a particular excitation wavelength, or to reveal a visible color. The encrypted marker can be developed in situ, or a sample can be removed by brushing, scraping, swabbing or scratching the marked object or item and developing the encrypted marker or a sample thereof with the appropriate developer to reveal an overt marker or optical signal. The marker can be revealed by exposure of the encrypted marker or a sample thereof to the developer in any suitable form, such as a solution, a slurry, a swab, a solid (such as in granular form), or a gas or a vapor that includes a developer.
Methods for distinguishing between cotton cultivars of a specific species by analyzing a sample of mature cotton fibers from raw cotton materials or from textile goods are disclosed. DNA is extracted from the mature cotton fiber sample and subjected to PCR techniques which enable the identification of the cultivar of a particular cotton species utilized in the textile or cotton material of interest.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
09 - Scientific and electric apparatus and instruments
Goods & Services
Laboratory apparatus and instruments, namely, polymerase chain reaction apparatus for conducting DNA amplifications, and parts for the aforesaid goods; computer software programs for controlling laboratory equipment and parts thereof
59.
ELECTRON BEAM PRE-TREATMENT OF INORGANIC AND POLYMER SURFACES FOR BONDING OF DETECTABLE MARKER MOLECULES
A method of binding a detectable marker to a surface comprising the steps of exposing the surface to an electron beam to produce an electron beam-treated surface; applying a detectable marker to the electron beam-treated surface; and thereby producing a surface-bound detectable marker on the treated surface. The detectable marker can be any suitable marker such as an optical marker, a dye, a fluorophore, a biomolecule, a metal, or a rare earth element. Also provided is a composition including a detectable marker immobilized on a surface pre-treated with an electron beam.
The invention provides a method of marking an item with naturally-derived or synthetic non-natural polymeric marker molecules, such as a DNA or Peptide marker in conjunction with optional visible or rapid scan reporters for authenticating or tracking, in which the method includes providing an item for marking, and applying a medium including a DNA marker to the item. The invention further provides methods for stably binding and immobilizing activated deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. Also provided are methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. The invention also provides a method of marking an item with a DNA marker for authenticating or tracking, in which the method includes providing a medium including a DNA marker, and molding the medium including the DNA marker to provide all or part of the item. The DNA marker encodes information unique to the item and/or the model of the item as desired.
G07D 7/14 - Testing specially adapted to determine the identity or genuineness of valuable papers or for segregating those which are unacceptable, e.g. banknotes that are alien to a currency using chemical means
A multi-mode reader instrument capable of detecting and determining digital data from a signal from one or more markers, indicia or taggants on an object, the markers, indicia or taggants such as a bar code, a QR code, an RFID, an optical compound, a fluorescent compound, a phosphorescent compound, a DNA taggant, an upconverting phosphor (UCP), a chemical dye, a digitized image, a radioactive compound, an olfactory compound or a thermal attribute of the object is provided. Also, provided is a method and a system for identifying an object, the system includes: a multi-mode reader instrument for detecting data from a signal from one or more markers, indicia or taggants on an object and assignment of digital code for the marker and a database for securing and retrieving information relevant to the item.
Provided are a method and device for marking an article for security, tracking or authentication. The method includes depositing a solution comprising a nucleic acid marker onto at least a portion of the article. The nucleic acid marker may be activated, for example, by adding a functional group to the nucleic acid marker. The activation of the nucleic acid marker may be performed by exposure to alkaline conditions. The method is well suited for marking fibers and textiles, as well as many other items.
The invention provides methods for stably binding and immobilizing deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. The alkaline conditions are produced by mixing the deoxyribonucleic acid with an alkaline solution having a pH of about 9.0 or higher, and contacting the deoxyribonucleic acid to the substrate. The immobilized DNA can be used as a taggant and can be used in combination with other detectable taggants, such as optical reporters. Methods for authentication of a DNA marked object are also provided.
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
Methods for incorporating and/or immobilizing security markers by exposure to an electromagnetic pulse, such as for instance a LASER pulse, to produce a marked object that can be authenticated only by using proprietary biological, chemical or physical analysis, the method includes: exposing a surface of the object to be marked to an electromagnetic pulse to activate the surface or a coating on the surface, and exposing the surface to a detectable marker molecule and thereby immobilizing the detectable marker molecule, such as a biological marker molecule, e.g. DNA on the surface of the object. The method of marking the object may include exposing a photo-polymerizable monomer on at least a portion of the surface of an object to be marked to a LASER pulse to initiate a reaction to cross link the photo-polymerizable monomer binding, trapping or encapsulating a detectable marker on the surface of the object.
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
B01J 13/18 - In situ polymerisation with all reactants being present in the same phase
65.
DNA MARKING OF PREVIOUSLY UNDISTINGUISHED ITEMS FOR TRACEABILITY
The invention provides a method of marking an item with a DNA marker for authenticating or tracking, wherein the method includes providing an item for marking; and affixing to the item, or embedding into the item a medium comprising a DNA marker; wherein the DNA marker encodes information unique to said item. The affixing can be by printing, molding, varnishing, stamping, painting, writing, coating or by labeling.
Methods for distinguishing between cotton species by analyzing a sample of mature cotton fibers from raw cotton materials or from textile goods are disclosed. DNA is extracted from the mature cotton fiber sample and subjected to PCR techniques which enable the identification of the species of cotton utilized in the textile or cotton material of interest.
The invention provides methods for stably binding and immobilizing deoxyribonucleic acid onto objects and substrates. The method includes exposing the deoxyribonucleic acid to alkaline conditions, and contacting the deoxyribonucleic acid to the object or substrate. The alkaline conditions are produced by mixing the deoxyribonucleic acid with an alkaline solution having a pH of about 9.0 or higher, and contacting the deoxyribonucleic acid to the substrate. The immobilized DNA can be used as a taggant and can be used in combination with other detectable taggants, such as optical reporters. Methods for authentication of a DNA marked object are also provided.
A method of marking an inventory item includes providing an activatable smoke generator and a reservoir for holding a smoke fluid and adapted to provide a flow of smoke fluid to the generator. The reservoir contains a smoke fluid including a carrier nucleic acid having a uniquely identifiable sequence, and upon activation of the smoke generator, marker smoke is generated and targeted to flow over the inventory item. The method further includes activating the smoke generator to produce the marker smoke including the carrier nucleic acid so as to cause the marker smoke to flow over the inventory item and thereby to detectably mark the inventory item with carrier nucleic acid.
G08B 15/02 - Identifying, scaring or incapacitating burglars, thieves or intruders, e.g. by explosives with smoke, gas, or coloured or odorous powder or liquid
69.
SECURITY SYSTEM AND METHOD OF MARKING AN INVENTORY ITEM AND/OR PERSON IN THE VICINITY
A method of marking an inventory item includes providing an activatable smoke generator and a reservoir for holding a smoke fluid and adapted to provide a flow of smoke fluid to the generator. The reservoir contains a smoke fluid including a carrier nucleic acid having a uniquely identifiable sequence, and upon activation of the smoke generator, marker smoke is generated and targeted to flow over the inventory item. The method further includes activating the smoke generator to produce the marker smoke including the carrier nucleic acid so as to cause the marker smoke to flow over the inventory item and thereby to detectably mark the inventory item with carrier nucleic acid.
G08B 15/02 - Identifying, scaring or incapacitating burglars, thieves or intruders, e.g. by explosives with smoke, gas, or coloured or odorous powder or liquid
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
70.
USE OF PERTURBANTS TO FACILITATE INCORPORATION AND RECOVERY OF TAGGANTS FROM POLYMERIZED COATINGS
The invention provides methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. Methods for authentication of a taggant marked object are also provided.
The invention provides methods for increasing the recoverability of taggants from an object. The methods include the steps of incorporating a taggant into a solution; mixing the solution including the taggant with a perturbant to form a first perturbant taggant solution; mixing the first perturbant taggant solution with a polymer to form a second perturbant taggant polymer solution; and applying the second perturbant taggant polymer solution to at least a portion of the object to form a taggant-coated object. Methods for authentication of a taggant marked object are also provided.
A verifiably identifiable object that includes a primary taggant encoding a readable encrypted first identifier of the object encrypted by a first method and a secondary taggant encoding a readable encrypted second identifier of the object optionally encrypted by a second method. The primary taggant can be a physical identification taggant, such as DNA including an authentication sequence, and the secondary taggant can be a digital identification taggant. The digital identification taggant encodes information validating the physical identification taggant, such as by referencing information embodied in the physical taggant, e.g. the defined sequence within the DNA. Also included is a method and system for identification and/or authentication of an object that includes a primary taggant encoding a readable encrypted first identifier of the object encrypted by a first method and a secondary taggant encoding a readable encrypted second identifier of the object encrypted by a second method.
G06K 19/10 - Record carriers for use with machines and with at least a part designed to carry digital markings characterised by the kind of the digital marking, e.g. shape, nature, code using markings of different kinds in the same record carrier, e.g. one marking being sensed by optical and the other by magnetic means at least one kind of marking being used for authentication, e.g. of credit or identity cards
The invention provides a composition including DNA bonded to a plasma-treated surface, the plasma can be any suitable plasma, such as an argon plasma, a compressed air plasma, a flame-based plasma or a vacuum plasma. Surfaces treatable by the methods of the invention include ceramic, metal, fabric and organic polymer surfaces. The DNA can be any DNA, such as a marker DNA, which can be linear or circular, single-stranded or double stranded and from about 25 bases to about 10,000 bases in length. Also provided is a method of binding DNA to a surface, including the steps of exposing the surface to a plasma to produce a plasma-treated surface; and applying DNA to the plasma-treated surface to produce surface bound DNA on the treated surface. A system for binding DNA to a surface is also disclosed, the system includes a plasma generator adapted to treating a surface with a plasma to produce a plasma-treated surface; and an applicator containing DNA adapted to applying DNA to the plasma-treated surface to produce surface bound DNA on the plasma-treated surface.
Methods for distinguishing between cotton cultivars of a specific species by analyzing a sample of mature cotton fibers from raw cotton materials or from textile goods are disclosed. DNA is extracted from the mature cotton fiber sample and subjected to PCR techniques which enable the identification of the cultivar of a particular cotton species utilized in the textile or cotton material of interest.
Disclosed herein is an efficient, high speed production scale synthesis method for high molecular weight organic substances, such as DNA. The invention includes a method of conducting a polymerase chain reaction which comprises transporting a liquid through polymeric tubing disposed through a first reaction cycle region and at least a second reaction cycle region, each of which regions comprises at least a first and a second temperature zone, the temperature in each zone of said at least second region being substantially identical to the corresponding first and second zones in said first region, wherein said liquid is an aqueous solution comprising polymerase chain reaction reactants and a surface absorbing polymer.
Methods for distinguishing between cotton species by analyzing a sample of mature cotton fibers from raw cotton materials or from textile goods are disclosed. DNA is extracted from the mature cotton fiber sample and subjected to PCR techniques which enable the identification of the species of cotton utilized in the textile or cotton material of interest.
Methods for distinguishing between cotton cultivars of a specific species by analyzing a sample of mature cotton fibers from raw cotton materials or from textile goods are disclosed. DNA is extracted from the mature cotton fiber sample and subjected to PCR techniques which enable the identification of the cultivar of a particular cotton species utilized in the textile or cotton material of interest.
A material for indelibly and uniquely marking an article for identification purposes includes a mixture including between about 1% and 10% by weight fluorescent identifier, DNA, and the remainder including predominantly a solvent.
C09K 3/30 - Materials not provided for elsewhere for aerosols
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
G08B 15/02 - Identifying, scaring or incapacitating burglars, thieves or intruders, e.g. by explosives with smoke, gas, or coloured or odorous powder or liquid
A method for authenticating and verifying a pharmaceutical item to be genuine is described. The method for authenticating a tablet comprises applying a particular nucleic acid material associated with a particular sequence of nucleic acid bases to a tablet or capsule. The method also comprises collecting a sample of the tablet and verifying the tablet is genuine by detecting the particular nucleic acid material.
This invention provides compositions that have a light emitting reporter linked to biomolecules, preferably, nucleotide oligomers. The light reporter particles are silylated and functionalized to produce a coated light reporter particle, prior to covalently linking the biomolecules to the light reporter particle. The light reporter particles of the invention can be excited by a light excitation source such as UV or IR light, and when the biomolecule is DNA, the attached DNA molecule(s) are detectable by amplification techniques such as PCR.
This invention pertains to methods for authenticating an article comprising tagging the article with light emitting optical reporter particles, and more specifically tagging the articles with up-converting phosphor particles (UCP), linked to nucleic acids of detectable sequence.
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
85.
METHOD FOR A CONTINUOUS RAPID THERMAL CYCLE SYSTEM
An efficient, high speed production scale synthesis method for high molecular weight organic substances such as DNA by methods which require multiple temperature environments. In a Polymerase Chain Reaction operation, a substantially ho-mogeneous liquid of the reactants is conveyed by tubing through a minimum of two temperature zones in the presence of a sufficient amount of a surface absorbing polymer to both condition the tubing and protect the catalyzing enzyme so as to increase production, efficiency and minimize down time needed to regenerate the system for further use. In particular, a block copolymer of ethylene oxide and propylene oxide is used.
09 - Scientific and electric apparatus and instruments
13 - Firearms; explosives
45 - Legal and security services; personal services for individuals.
Goods & Services
Security products for protection against assault, and intrusion; security control apparatus and instruments; security monitoring apparatus for the detection of intruders; security devices for premises; personal security apparatus including personal alarms; security marking equipment. Apparatus for personal defence and for defending premises, including devices for marking attackers and intruders. Advisory services relating to the security of premises and of personal security; advisory services relating to security; provision of security monitoring services; security services for buildings; forensic services for criminal investigations.
09 - Scientific and electric apparatus and instruments
13 - Firearms; explosives
45 - Legal and security services; personal services for individuals.
Goods & Services
Security products for protection against assault, and intrusion; security control apparatus and instruments; security monitoring apparatus for the detection of intruders; security devices for premises; personal security apparatus including personal alarms; security marking equipment. Apparatus for personal defence and for defending premises, including devices for marking attackers and intruders. Advisory services relating to the security of premises and of personal security; advisory services relating to security; provision of security monitoring services; security services for buildings; forensic services for criminal investigations.
88.
SYSTEM AND METHOD FOR AUTHENTICATING MULTIPLE COMPONENTS ASSOCIATED WITH A PARTICULAR PRODUCT
A method for authenticating a product where the product is composed of a plurality of components is described. The method for authenticating the product comprises providing a liquid compound, e.g. paint, that comprises at least one invisible market, e.g. nucleic acid, in which the compound is associated with a first entity. The method then proceeds to apply the compound to the surface of the product at the juncture of at least two components. The method also comprises associating the application of the compound to the at least two components with the first entity.
16 - Paper, cardboard and goods made from these materials
Goods & Services
Anti-counterfeiting system comprised of DNA coating, namely, marking ink and coatings containing DNA for the encryption and authentification of objects
16 - Paper, cardboard and goods made from these materials
Goods & Services
Inks using nucleic acids for identification of items to which ink is applied Paper labels using ink containing nucleic acid for authentication of the labels
