|
|
Found results for
 patents
1.
|
SYNTHETIC HEXASACCHARIDES MIMICS OF HEPARIN SHOWING HEPARANASE INHIBITION ACTIVITY
| Document Number |
03254387 |
| Status |
Pending |
| Filing Date |
2023-07-06 |
| Open to Public Date |
2024-01-18 |
| Owner |
CENTRO ALTA TECNOLOGIA ISTITUTO DI RICERCHE CHIMICHE E BIOCHIMICHE G. RONZONI S.R.L. (Italy)
|
| Inventor |
- Naggi, Annamaria
- Ni, Ming Hong
- Petitou, Maurice
|
IPC Classes ?
- A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
- C08B 37/00 - Preparation of polysaccharides not provided for in groups Derivatives thereof
- C08L 5/10 - HeparinDerivatives thereof
|
2.
|
SYNTHETIC HEXASACCHARIDES MIMICS OF HEPARIN SHOWING HEPARANASE INHIBITION ACTIVITY
| Application Number |
EP2023068684 |
| Publication Number |
2024/012972 |
| Status |
In Force |
| Filing Date |
2023-07-06 |
| Publication Date |
2024-01-18 |
| Owner |
CENTRO ALTA TECNOLOGIA ISTITUTO DI RICERCHE CHIMICHE E BIOCHIMICHE G. RONZONI S.R.L. (Italy)
|
| Inventor |
- Naggi, Annamaria
- Petitou, Maurice
- Ni, Ming Hong
|
Abstract
The present invention is directed to hexasaccharides mimetics of heparins presenting remarkable heparanase inhibition activity. The compounds have formula (I), wherein R1233Na, NHAc; R2233Na, NHAc; R3is selected from the group consisting of Bn, H; R433Na; R522Na; R6is selected from the group consisting of Me, Ethyl, Alkyl, alkyl azide, alkynyl, cholestanol aglycon; R722OH, COOH.
IPC Classes ?
- C08B 37/00 - Preparation of polysaccharides not provided for in groups Derivatives thereof
- A61K 31/715 - Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkagesDerivatives thereof, e.g. ethers, esters
- C08L 5/10 - HeparinDerivatives thereof
|
|
