Spryson Inc.

United States of America

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Date
2024 1
2021 3
2020 4
Before 2020 23
IPC Class
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement 20
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes 16
A61B 3/14 - Arrangements specially adapted for eye photography 14
A61B 5/00 - Measuring for diagnostic purposes Identification of persons 12
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient 8
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NICE Class
10 - Medical apparatus and instruments 6
05 - Pharmaceutical, veterinary and sanitary products 4
09 - Scientific and electric apparatus and instruments 4
42 - Scientific, technological and industrial services, research and design 4
37 - Construction and mining; installation and repair services 3
Status
Pending 5
Registered / In Force 26

1.

Automated Data Acquisition, Appraisal and Analysis in Noninvasive Rapid Screening of Neuro-Otologic Conditions Using Combination of Subject's Objective Oculomotor Vestibular and Reaction Time Analytic Variables

      
Application Number 18545661
Status Pending
Filing Date 2023-12-19
First Publication Date 2024-09-05
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D.
  • Shirey, Ian

Abstract

An automated data acquisition, appraisal and analysis in noninvasive rapid screening of neuro-otologic condition using combination of subject's objective oculomotor, vestibular and reaction time analytic variables, comprises the steps of: establishing an oculomotor, vestibular and reaction time testing protocol for specific neuro-otologic condition which protocol included eye tracking aspects and which protocol obtains a combination of a subject's objective oculomotor, vestibular and reaction time analytic variables; coupling an eye tracker to subject; automatically establishing a region of interest for the eye tracker in which the region of interest is centered on the subject's pupils; conducting the oculomotor, vestibular and reaction time testing protocol using pre-programmed/automated voice instructions to the subject to obtain a combination of a subject's objective oculomotor, vestibular and reaction time analytic variables; and calculating and displaying a normalized composite test protocol score (0-1) on graphical progressive background.

IPC Classes  ?

  • A61B 5/16 - Devices for psychotechnicsTesting reaction times
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/12 - Audiometering

2.

Vergence recovery convalescence using dynamic vergence testing platform including 3D head mounted display system with integrated eye tracking technology

      
Application Number 17228458
Grant Number 11857258
Status In Force
Filing Date 2021-04-12
First Publication Date 2021-11-11
Grant Date 2024-01-02
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D.
  • Ashmore, Robin C.

Abstract

An objective testing of vergence dysfunction comprising the steps of: providing a head mounted goggle based stimulus generating eye tracking unit to the subject; presenting visual stimulus to the subject, wherein the visual stimulus is in the head mounted goggle based system and forms the optical target stimulus for at least one vergence test; obtaining objective physiologic response of the subject from the head mounted goggle unit based upon each of the visual stimulus presented to the subject in each test; and using the objective physiologic responses to diagnose the presence of vergence dysfunction. On objective portable head mounted goggle based stimulus generating eye tracking unit for vergence testing is discloses as is a method of method of vergence recovery convalescence.

IPC Classes  ?

  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
  • G02B 27/01 - Head-up displays

3.

NEUROLOGICAL REHABILITATION AND TRAINING METHOD UTILIZING OCULOMOTOR, VISUAL AND/OR VESTIBULAR REHABILITATION TASKS ON SUBJECTS WITH PHARMACOLOGICALLY INDUCED NEUROPLASTICITY

      
Application Number 17316077
Status Pending
Filing Date 2021-05-10
First Publication Date 2021-10-28
Owner SPRYSON INC. (USA)
Inventor
  • Schroeder, John Howison
  • Ashmore, Robin C.
  • Kiderman, Alexander D.
  • Doyle, Peter Charles

Abstract

A Neurological Rehabilitation method utilizing oculomotor, visual and/or vestibular rehabilitation tasks on subjects with pharmacologically induced neuroplasticity comprising the steps of Inducing neuroplasticity in a subject through administering of a neuroplasticity medicament; Providing a oculomotor, visual and vestibular rehabilitation task platform configured to supply visual targets to a subject for oculomotor, visual and vestibular rehabilitation tasks and track and record eye movement of the subject during oculomotor, visual and vestibular rehabilitation tasks; Performing oculomotor, visual and/or vestibular rehabilitation tasks on the platform with subjects during periods of pharmacologically induced neuroplasticity. The neuroplasticity medicament generally is comprising at least one of an antidepressant, a Brain Derived Neuro trophic factor enhancer, a steroid, a psychedelic, valproic acid, NDRI's, lithium carbonate, Metformin, N-Acetylcystine, and Human Growth Hormone.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61K 31/155 - Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (HN=C(OH)NH2), isothiourea (HN=C(SH)—NH2)
  • A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
  • A61K 38/27 - Growth hormone [GH], i.e. somatotropin
  • A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb

4.

NEUROLIGNFIT

      
Application Number 211496400
Status Pending
Filing Date 2021-06-17
Owner Spryson, Inc. (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

(1) Pharmaceutical preparations for the treatment of neurological diseases and disorders; pharmaceutical preparations for the treatment of the symptoms of concussion; nutraceutical preparations for the treatment of neurological diseases and disorders; nutraceutical preparations for the treatment of the symptoms of concussion; nutritional supplements for general health and well-being; dietary supplements for general health and well-being; vitamin and mineral supplements (2) Wearable electronic devices and computer hardware, namely, headsets and wearable activity trackers for neurological signal detection; Wearable electronic devices, namely, headsets and wearable activity trackers and computer hardware for capturing, tracking, processing and analyzing high speed digital images of the eye for use in assessing and improving human brain functions and potentials; Wearable electronic devices, namely, headsets and wearable activity trackers and computer hardware for use in the field of assessing and improving human brain functions and potentials; Wearable electronic devices, namely, headsets and wearable activity trackers that collect physical activity, eye activity, brain activity, and biometric data and communicate such data to personal digital assistants, tablets, smart phones, and personal computers wirelessly and through internet websites; Computer hardware and software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; downloadable applications for mobile phones for use in measuring and improving neurological health; downloadable application software for alerts, messages, emails, and reminders, and for receiving, recording, organizing, manipulating, reviewing, analyzing and transmitting neurological signal data, physical activity data, brain activity data, and biometric data; medical device, namely, a head mounted display for evaluating, diagnosing and treating vestibular and neurotologic disorders; medical device, namely, a video screen, digital signal and video processors, and headset, provided together as a kit for medical purposes, for evaluating, diagnosing and treating vestibular and neurotologic disorders; (3) Apparatus for performing oculographic analysis, namely, video oculography, video nystagmography, and video frenzel systems; medical devices for diagnosing and measuring concussion; apparatus used in implementing diagnosis tests for vestibular and neurotologic disorders; (1) Non-downloadable computer software for displaying, aggregating, analyzing and organizing data and information in the field of neurological health; non-downloadable computer software for use in measuring and improving human brain functions and neurological health; non-downloadable computer software for the evaluation, diagnosis and treatment of vestibular and neurological disorders; non-downloadable computer software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; Software as a service (SaaS) for use in designing, creating and analyzing data, metrics and reports in the areas of brain health and neurological health;

5.

NEUROLIGN

      
Application Number 018361810
Status Registered
Filing Date 2020-12-22
Registration Date 2021-05-15
Owner SPRYSON, INC. (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 37 - Construction and mining; installation and repair services
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Pharmaceutical preparations for the treatment of neurological diseases and disorders; pharmaceutical preparations for the treatment of the symptoms of concussion; nutraceutical preparations for the treatment of neurological diseases and disorders; nutraceutical preparations for the treatment of the symptoms of concussion.. Computer hardware and software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; computer hardware and software for capturing, tracking, processing and analyzing high speed digital images of the eye; downloadable applications for mobile phones for use in diagnosing and measuring concussion.. Apparatus for performing oculographic analysis including video oculography, video nystagmography, and video frenzel systems; medical devices for diagnosing and measuring concussion; apparatus used in implementing diagnosis tests for vestibular and neurotologic disorders; medical device, namely, a head mounted display for evaluating, diagnosing and treating vestibular and neurotologic disorders; medical device, namely, a video screen, processor, and headset, provided together as a kit, for evaluating, diagnosing and treating vestibular and neurotologic disorders.. Installation, maintenance, diagnosis and repair of medical diagnostic apparatus and instruments.. Computer software installation and maintenance; calibration of medical diagnostic apparatus and instruments; professional technical support services, namely, troubleshooting of computer software problems related to medical diagnostic apparatus and instruments; providing non-downloadable computer software for the evaluation, diagnosis and treatment of vestibular and neurotologic disorders; providing downloadable applications for mobile phones for use in diagnosing and measuring concussion..

6.

NEUROLIGN

      
Serial Number 90021552
Status Pending
Filing Date 2020-06-25
Owner SPRYSON, INC. ()
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 37 - Construction and mining; installation and repair services
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Pharmaceutical preparations for the treatment of neurological diseases and disorders, namely, concussion, multiple sclerosis, dementia, mild cognitive impairment, Parkinson's disease, attention deficit hyperactivity disorder, Alzheimer's disease, strabismus and vestibular migraine; pharmaceutical preparations for the treatment of the symptoms of concussion; nutraceutical preparations for the treatment of neurological diseases and disorders, namely, concussion, multiple sclerosis, dementia, mild cognitive impairment, Parkinson's disease, attention deficit hyperactivity disorder, Alzheimer's disease, strabismus and vestibular migraine; nutraceutical preparations for the treatment of the symptoms of concussion Computer hardware and downloadable and recordable software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; computer hardware and downloadable and recordable software for capturing, tracking, processing and analyzing high speed digital images of the eye; downloadable software applications for mobile phones for use in diagnosing and measuring concussion Apparatus for performing oculographic analysis including video oculography, video nystagmography, and video frenzel systems; medical devices for diagnosing and measuring concussion; apparatus used in implementing diagnosis tests for vestibular and neurotologic disorders; medical device, namely, a head mounted display for evaluating, diagnosing and treating vestibular and neurotologic disorders; medical device, namely, a video screen, processor, and headset, provided together as a kit, for evaluating, diagnosing and treating vestibular and neurotologic disorders Installation, maintenance, diagnosis and repair of medical diagnostic apparatus and instruments Computer software installation and maintenance; calibration of medical diagnostic apparatus and instruments; professional technical support services, namely, troubleshooting of computer software problems related to medical diagnostic apparatus and instruments; providing temporary use of non-downloadable computer software for the evaluation, diagnosis and treatment of vestibular and neurotologic disorders

7.

NEUROLIGN

      
Application Number 203644500
Status Pending
Filing Date 2020-06-25
Owner Spryson, Inc. (USA)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 37 - Construction and mining; installation and repair services
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

(1) Pharmaceutical preparations for the treatment of neurological diseases and disorders; pharmaceutical preparations for the treatment of the symptoms of concussion; nutraceutical preparations for the treatment of neurological diseases and disorders; nutraceutical preparations for the treatment of the symptoms of concussion; (2) Computer hardware and software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; computer hardware and software for capturing, tracking, processing and analyzing high speed digital images of the eye; downloadable applications for mobile phones for use in diagnosing and measuring concussion; medical device, namely, a head mounted display for evaluating, diagnosing and treating vestibular and neurotologic disorders; medical device, namely, a video screen, digital signal and video processors, and headset, provided together as a kit for medical purposes, for evaluating, diagnosing and treating vestibular and neurotologic disorders; (3) Apparatus for performing oculographic analysis, namely, video oculography, video nystagmography, and video frenzel systems; medical devices for diagnosing and measuring concussion; apparatus used in implementing diagnosis tests for vestibular and neurotologic disorders; (1) Installation, maintenance, diagnosis and repair of medical diagnostic apparatus and instruments; (2) Computer software installation and maintenance; calibration of medical diagnostic apparatus and instruments; professional technical support services, namely, troubleshooting of computer software problems related to medical diagnostic apparatus and instruments; providing non-downloadable computer software for the evaluation, diagnosis and treatment of vestibular and neurotologic disorders;

8.

Method for head impulse test

      
Application Number 16773077
Grant Number 11826158
Status In Force
Filing Date 2020-01-27
First Publication Date 2020-06-18
Grant Date 2023-11-28
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Shirey, Ian A
  • Furman, Joseph M

Abstract

A system and associated method for computerized rotational head impulse test (crHIT) to assess the semicircular canals of the human vestibular system clinically in patients with balance disorders. The system utilizes a rotary chair combined with a head mounted VOG system with head tracking sensors. The crHIT protocol uses the same physiologic principles as the known video head impulse test (vHIT). The crHIT utilizes whole-body rotation via the chair to yield a persistent controlled, repeatable, comfortable, reliable stimulus can be delivered while recording eye movements with video-oculogaphy.

IPC Classes  ?

  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • G02F 1/133 - Constructional arrangementsOperation of liquid crystal cellsCircuit arrangements
  • G02F 1/1335 - Structural association of cells with optical devices, e.g. polarisers or reflectors
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • G01J 1/42 - Photometry, e.g. photographic exposure meter using electric radiation detectors

9.

Objective testing of vergence dysfunction for using dynamic vergence testing platform including 3D head mounted display system with integrated eye tracking technology

      
Application Number 16109485
Grant Number 10973409
Status In Force
Filing Date 2018-08-22
First Publication Date 2019-03-21
Grant Date 2021-04-13
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D.
  • Ashmore, Robin C.

Abstract

An objective testing of vergence dysfunction comprising the steps of: providing a head mounted goggle based stimulus generating eye tracking unit to the subject; presenting visual stimulus to the subject, wherein the visual stimulus is in the head mounted goggle based system and forms the optical target stimulus for at least one vergence test; obtaining objective physiologic response of the subject from the head mounted goggle unit based upon each of the visual stimulus presented to the subject in each test; and using the objective physiologic responses to diagnose the presence of vergence dysfunction. On objective portable head mounted goggle based stimulus generating eye tracking unit for vergence testing is discloses as is a method of method of vergence recovery convalescence.

IPC Classes  ?

  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
  • G02B 27/01 - Head-up displays

10.

Method and apparatus for mTBI diagnosis implementing eye movement and pupil movement analysis in objective vergence testing

      
Application Number 15897137
Grant Number 11419493
Status In Force
Filing Date 2018-02-14
First Publication Date 2018-08-30
Grant Date 2022-08-23
Owner SPRYSON INC. (USA)
Inventor
  • Balaban, Carey D.
  • Szczupak, Mikhaylo
  • Hoffer, Michael E.
  • Ashmore, Robin C.
  • Kiderman, Alexander

Abstract

An objective screening platform for mTBI screening includes a vergence testing stimulus generator visible to a subject and configured for presenting visual stimulus to a subject which forms an optical target stimulus for at least one vergence test; at least one data acquisition unit for obtaining objective physiologic responses of the subject unit based upon each of the visual stimulus presented to the subject in each test, wherein the objective physiologic responses for each test include at least one eye position parameter and at least one pupil area parameter; and a controller configured for using at least one eye position parameter and at least one pupil area parameter to screen for the presence of mTBI of the subject.

IPC Classes  ?

  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/12 - Audiometering
  • A61B 3/08 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing binocular or stereoscopic vision, e.g. strabismus
  • A61B 90/50 - Supports for surgical instruments, e.g. articulated arms

11.

Apparatus and method for computerized rotational head impulse test

      
Application Number 15596886
Grant Number 10542927
Status In Force
Filing Date 2017-05-16
First Publication Date 2017-12-28
Grant Date 2020-01-28
Owner SPRYSON INC. (USA)
Inventor
  • Furman, Joseph M
  • Kiderman, Alexander D
  • Shirey, Ian A

Abstract

A system and associated method for computerized rotational head impulse test (crHIT) to assess the semicircular canals of the human vestibular system clinically in patients with balance disorders. The system utilizes a rotary chair combined with a head mounted VOG system with head tracking sensors. The crHIT protocol uses the same physiologic principles as the known video head impulse test (vHIT). The crHIT utilizes whole-body rotation via the chair to yield a persistent controlled, repeatable, comfortable, reliable stimulus can be delivered while recording eye movements with video-oculogaphy.

IPC Classes  ?

  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • G02F 1/133 - Constructional arrangementsOperation of liquid crystal cellsCircuit arrangements
  • G02F 1/1335 - Structural association of cells with optical devices, e.g. polarisers or reflectors
  • G01J 1/42 - Photometry, e.g. photographic exposure meter using electric radiation detectors

12.

Portable google based VOG system with comparative left and right eye ocular response analysis with MTBI analysis using percent of saccade function of smooth pursuit test

      
Application Number 15670553
Grant Number 10314485
Status In Force
Filing Date 2017-08-07
First Publication Date 2017-12-14
Grant Date 2019-06-11
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Shirey, Ian
  • Sweeney, Daniel
  • Eydelman, Yakov
  • Schroeder, John Howison

Abstract

A head mounted compact goggle based video oculography system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

IPC Classes  ?

  • A61B 3/06 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing light sensitivity, e.g. adaptationSubjective types, i.e. testing apparatus requiring the active assistance of the patient for testing colour vision
  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient

13.

Head mounted compact goggle based video oculography system with integral stimulus screen

      
Application Number 15013258
Grant Number 09723981
Status In Force
Filing Date 2016-02-02
First Publication Date 2017-01-26
Grant Date 2017-08-08
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Shirey, Ian
  • Sweeney, Daniel
  • Eydelman, Yakov
  • Schroeder, John Howison

Abstract

A head mounted compact goggle based video oculography system is configured for use in VOG-based neuro-otologic testing. The system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror within the goggle base; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.

IPC Classes  ?

  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
  • A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient

14.

Method of measuring and analyzing ocular response in a subject using stable pupillary parameters with video oculography system

      
Application Number 14953736
Grant Number 09596986
Status In Force
Filing Date 2015-11-30
First Publication Date 2016-06-02
Grant Date 2017-03-21
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Eydelman, Yakov
  • Schroeder, John Howison

Abstract

A method of measuring and analyzing an ocular response in a subject comprising the steps of: Providing a video oculography based system for the subject with the system configured to collect eye images in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one stimulus is presented to only one eye of the subject and configured to yield a pupil eye response from at least one eye of the subject; Calculating pupilometry measurements from the eye data, wherein the pupil measurements are calculated independently for the subject's left and right eyes for each stimulus presented to the subject, and wherein comparative left and right pupilometry measurements from the eye data are calculated; analyzing a subject's ocular response based upon at least one of the calculated pupilometry measurements.

IPC Classes  ?

  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient

15.

Noninvasive rapid screening of mild traumatic brain injury using combination of subject's objective oculomotor, vestibular and reaction time analytic variables

      
Application Number 14687871
Grant Number 10398309
Status In Force
Filing Date 2015-04-15
First Publication Date 2015-11-26
Grant Date 2019-09-03
Owner SPRYSON INC. (USA)
Inventor
  • Ashmore, Robin C.
  • Schroeder, Howison
  • Sweeney, Daniel
  • Kiderman, Alexander D
  • Sclabassi, Robert
  • Joos, Thomas
  • Frank, Greg
  • Baker, Thomas Vernon

Abstract

A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 5/16 - Devices for psychotechnicsTesting reaction times
  • G02B 27/01 - Head-up displays
  • G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,

16.

Method for objective diagnostics of internuclear opthalmopligia, ocular lateral pulsion, progressive supernuclear palsy and glissades eye movements

      
Application Number 14819643
Grant Number 09730583
Status In Force
Filing Date 2015-08-06
First Publication Date 2015-11-26
Grant Date 2017-08-15
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Eydelman, Yakov
  • Ives, Terri Evelyn

Abstract

A video oculography (VOG) system for calculation and display of Corrective Secondary Saccades Analysis is disclosed and utilized in a method for Objective Diagnostics of Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy and Glissades. The method comprises the steps of using a VOG system to calculate corrective saccades. The VOG based system is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion and collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy are calculated.

IPC Classes  ?

  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons

17.

Method and associated apparatus for detecting minor traumatic brain injury

      
Application Number 14284718
Grant Number 10743808
Status In Force
Filing Date 2014-05-22
First Publication Date 2015-01-15
Grant Date 2020-08-18
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Cinberg, James Z

Abstract

Minor traumatic brain injury is detected by operating (a) an image generator for presenting a visual stimulus having a predetermined movement across a visual field of a subject and (b) a sensor device for monitoring fast eye movement of the subject while the subject views the stimulus. The sensor device generates a signal encoding the subject's eye position. A computer or microprocessor operatively connected to the sensor device is configured for determining a magnitude for the fast eye velocity component.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 5/16 - Devices for psychotechnicsTesting reaction times
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient

18.

Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic optokinetic testing

      
Application Number 14336254
Grant Number 09039632
Status In Force
Filing Date 2014-07-21
First Publication Date 2014-11-06
Grant Date 2015-05-26
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Schroeder, Howison
  • Joos, Thomas
  • Frank, Greg
  • Sweeney, Daniel
  • Baker, Thomas Vernon

Abstract

A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol including optokinetic testing that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient

19.

Method corrective secondary saccades analysis with video oculography system for objective diagnostic of traumatic brain injury, internuclear opthalmopligia, ocular lateral pulsion and progressive supernuclear palsy and glissades

      
Application Number 14320613
Grant Number 09107616
Status In Force
Filing Date 2014-06-30
First Publication Date 2014-11-06
Grant Date 2015-08-18
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Eydelman, Yakov
  • Ives, Terri Evelyn

Abstract

A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.

IPC Classes  ?

  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons

20.

Method and apparatus for validating testing procedures in objective ophthalmic eye testing for eye evaluation applications requiring subject compliance with eye fixation to a visual target

      
Application Number 14216350
Grant Number 09301675
Status In Force
Filing Date 2014-03-17
First Publication Date 2014-10-30
Grant Date 2016-04-05
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Eydelman, Yakov
  • Schroeder, John Howison

Abstract

A method and associated apparatus for validating testing procedure in objective ophthalmic eye testing is implemented for eye evaluation applications requiring subject compliance with eye fixation to a visual target. The method comprises the steps of: supplying a predetermined visual fixation target to the subject in a predetermined location with an automated ophthalmic eye testing device, wherein the testing procedure of the eye evaluation application requires the subject to fixate upon the visual fixation stimulus; tracking the subject's gaze during at least the supplying of the predetermined visual fixation stimulus to the subject throughout the testing procedure of the eye evaluation application with a video based eye tracking system; and validating the testing procedure by at least one of i) indicating to the clinician when the subject's gaze location differs from the predetermined visual fixation stimulus by an amount greater than a predetermined threshold amount, and ii) having the automated ophthalmic eye testing device repeat at least portions of the testing procedures when the subject's gaze location differs from the predetermined visual fixation stimulus by an amount greater than a predetermined threshold amount.

IPC Classes  ?

  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement

21.

Method and apparatus for system synchronization in video oculography based neuro-otologic testing and evaluation

      
Application Number 14216981
Grant Number 09247870
Status In Force
Filing Date 2014-03-17
First Publication Date 2014-10-30
Grant Date 2016-02-02
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Shirey, Ian
  • Sweeney, Daniel

Abstract

A video oculography based neuro-otologic testing and evaluation apparatus and associated method comprises the steps of: Obtaining images of the subject's eyes with a digital camera; Selectively displaying visual stimulus to the subject on a display; Generating each visual stimulus to be displayed from a controller; Receiving and storing data signals from each digital camera in the controller; Calculating eye related data from the digital camera images and visual stimulus; Displaying the eye related data to users; Generating a video synchronization signal by the controller associated with each visual stimulus which identifies when the display is displaying the associated visual stimulus; Receiving and coupling the video synchronization signal with at least the eye data from the digital camera; and Synchronizing calculations based upon the eye data and the visual stimulus by the controller.

IPC Classes  ?

  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient

22.

Method of measuring and analyzing ocular response in a subject using stable pupillary parameters with video oculography system

      
Application Number 14216480
Grant Number 09198571
Status In Force
Filing Date 2014-03-17
First Publication Date 2014-10-23
Grant Date 2015-12-01
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Eydelman, Yakov
  • Schroeder, John Howison

Abstract

A method of measuring and analyzing an ocular response in a subject comprising the steps of: Providing a video oculography based system for the subject with the system configured to collect eye images in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one stimulus is presented to only one eye of the subject and configured to yield a pupil eye response from at least one eye of the subject; Calculating pupilometry measurements from the eye data, wherein the pupil measurements are calculated independently for the subject's left and right eyes for each stimulus presented to the subject, and wherein comparative left and right pupilometry measurements from the eye data are calculated; analyzing a subject's ocular response based upon at least one of the calculated pupilometry measurements.

IPC Classes  ?

  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient

23.

Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic testing

      
Application Number 14083145
Grant Number 09039631
Status In Force
Filing Date 2013-11-18
First Publication Date 2014-07-10
Grant Date 2015-05-26
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Schroeder, Howison
  • Joos, Thomas
  • Frank, Greg
  • Sweeney, Daniel
  • Baker, Thomas Vernon

Abstract

A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
  • A61B 3/032 - Devices for presenting test symbols or characters, e.g. test chart projectors

24.

Method and apparatus for corrective secondary saccades analysis with video oculography system

      
Application Number 13080981
Grant Number 08764193
Status In Force
Filing Date 2011-04-06
First Publication Date 2012-04-05
Grant Date 2014-07-01
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Eydelman, Yakov
  • Ives, Terri Evelyn

Abstract

A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.

IPC Classes  ?

  • A61B 3/14 - Arrangements specially adapted for eye photography

25.

Method of precision eye-tracking through use of iris edge based landmarks in eye geometry

      
Application Number 12420111
Grant Number 09655515
Status In Force
Filing Date 2009-04-08
First Publication Date 2010-04-15
Grant Date 2017-05-23
Owner SPRYSON INC. (USA)
Inventor
  • Schroeder, John Howison
  • Kiderman, Alexander D.

Abstract

In the field of eye tracking, greater accuracy or resolution in monitoring movement of the eye can be gained by digitizing the eye, and tracking the movement of a landmark with fixed size and a fixed location relative to the eye's local coordinate system. The edge of the iris can be used as such a fixed landmark. Through the location and or establishment of at least a portion of the outer edge of the iris and/or an iris center point, both large and small scale eye movements, including but not limited to micro-tremors, can be traced with a higher degree of accuracy. This will aid in the diagnosis of diseases, assessing state of consciousness, and defining brainstem death.

IPC Classes  ?

  • G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement

26.

Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using simulated distance visual stimulus device for neurologic testing

      
Application Number 12577143
Grant Number 08585609
Status In Force
Filing Date 2009-10-09
First Publication Date 2010-04-15
Grant Date 2013-11-19
Owner SPRYSON INC. (USA)
Inventor
  • Kiderman, Alexander D
  • Schroeder, Howison
  • Joos, Thomas
  • Frank, Greg

Abstract

A portable virtual reality device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons

27.

Integrated video and electro-oculography system

      
Application Number 11926564
Grant Number 09101296
Status In Force
Filing Date 2007-10-29
First Publication Date 2008-11-06
Grant Date 2015-08-11
Owner SPRYSON INC. (USA)
Inventor
  • Schroeder, John Howison
  • Kiderman, Alexander D
  • Joos, Thomas C.
  • Wuyts, Floris L.
  • Moore, Steven T
  • Macdougall, Hamish G

Abstract

A goggle based light-weight VOG/EOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection. The EOG system is incorporated directly into a goggle base. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. The VOG system may track and record 3-D movement of the eye, track pupil dilation, head position and goggle slippage. An animated eye display provides data in a more meaningful fashion. The VOG system is a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.

IPC Classes  ?

  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement

28.

Compact neuro-otologic, neuro-ophthalmologic testing device and dynamic visual acuity testing and desensitization platform

      
Application Number 11181019
Grant Number 08333472
Status In Force
Filing Date 2005-07-13
First Publication Date 2006-10-19
Grant Date 2012-12-18
Owner SPRYSON INC. (USA)
Inventor Kiderman, Alexander D.

Abstract

2 and at velocities in excess of 12000 degrees/second. The bandwidth of the XY interface is greater than 400 Hz, providing high image reproducibility. The repeatability and position accuracy of the target is +−3 arc-seconds and the field of range of the XY interface are about 60 degrees (i.e. about 60 degrees horizontal and 60 degrees vertical).

IPC Classes  ?

  • A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes

29.

Portable video oculography system

      
Application Number 10704529
Grant Number 07731360
Status In Force
Filing Date 2003-11-07
First Publication Date 2005-05-12
Grant Date 2010-06-08
Owner SPRYSON INC. (USA)
Inventor
  • Macdougall, Hamish G.
  • Kiderman, Alexander D.
  • Schroeder, John Howison
  • Joos, Thomas C.
  • Wuyts, Floris L.
  • Moore, Steven T.

Abstract

A goggle based light-weight VOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. An EOG system may also be incorporated directly into the goggle. The VOG system may track and record 3-D movement of the eye, track pupil dilation, head position and goggle slippage. An animated eye display provides data in a more meaningful fashion. The VOG system is a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.

IPC Classes  ?

  • A61B 3/14 - Arrangements specially adapted for eye photography
  • A61B 3/10 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions

30.

PURSUIT TRACKER

      
Serial Number 78461906
Status Registered
Filing Date 2004-08-04
Registration Date 2006-07-04
Owner SPRYSON INC. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Neuro-Otologic Diagnostic Testing and Therapeutic Equipment, namely neuro-otologic stimuli generators and response sensors

31.

I-PORTAL

      
Serial Number 78331271
Status Registered
Filing Date 2003-11-21
Registration Date 2006-04-04
Owner SPRYSON INC. ()
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Video-Occulography System for tracking patient eye movement, comprised of a video camera for obtaining eye and other physiologic image data, a camera mounting unit, a processing unit for processing the physiologic video data, and a display for displaying the processed pysiologic data