Automated Data Acquisition, Appraisal and Analysis in Noninvasive Rapid Screening of Neuro-Otologic Conditions Using Combination of Subject's Objective Oculomotor Vestibular and Reaction Time Analytic Variables
An automated data acquisition, appraisal and analysis in noninvasive rapid screening of neuro-otologic condition using combination of subject's objective oculomotor, vestibular and reaction time analytic variables, comprises the steps of: establishing an oculomotor, vestibular and reaction time testing protocol for specific neuro-otologic condition which protocol included eye tracking aspects and which protocol obtains a combination of a subject's objective oculomotor, vestibular and reaction time analytic variables; coupling an eye tracker to subject; automatically establishing a region of interest for the eye tracker in which the region of interest is centered on the subject's pupils; conducting the oculomotor, vestibular and reaction time testing protocol using pre-programmed/automated voice instructions to the subject to obtain a combination of a subject's objective oculomotor, vestibular and reaction time analytic variables; and calculating and displaying a normalized composite test protocol score (0-1) on graphical progressive background.
A61B 5/16 - Devices for psychotechnicsTesting reaction times
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
Vergence recovery convalescence using dynamic vergence testing platform including 3D head mounted display system with integrated eye tracking technology
An objective testing of vergence dysfunction comprising the steps of: providing a head mounted goggle based stimulus generating eye tracking unit to the subject; presenting visual stimulus to the subject, wherein the visual stimulus is in the head mounted goggle based system and forms the optical target stimulus for at least one vergence test; obtaining objective physiologic response of the subject from the head mounted goggle unit based upon each of the visual stimulus presented to the subject in each test; and using the objective physiologic responses to diagnose the presence of vergence dysfunction. On objective portable head mounted goggle based stimulus generating eye tracking unit for vergence testing is discloses as is a method of method of vergence recovery convalescence.
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
NEUROLOGICAL REHABILITATION AND TRAINING METHOD UTILIZING OCULOMOTOR, VISUAL AND/OR VESTIBULAR REHABILITATION TASKS ON SUBJECTS WITH PHARMACOLOGICALLY INDUCED NEUROPLASTICITY
A Neurological Rehabilitation method utilizing oculomotor, visual and/or vestibular rehabilitation tasks on subjects with pharmacologically induced neuroplasticity comprising the steps of Inducing neuroplasticity in a subject through administering of a neuroplasticity medicament; Providing a oculomotor, visual and vestibular rehabilitation task platform configured to supply visual targets to a subject for oculomotor, visual and vestibular rehabilitation tasks and track and record eye movement of the subject during oculomotor, visual and vestibular rehabilitation tasks; Performing oculomotor, visual and/or vestibular rehabilitation tasks on the platform with subjects during periods of pharmacologically induced neuroplasticity. The neuroplasticity medicament generally is comprising at least one of an antidepressant, a Brain Derived Neuro trophic factor enhancer, a steroid, a psychedelic, valproic acid, NDRI's, lithium carbonate, Metformin, N-Acetylcystine, and Human Growth Hormone.
A61K 31/198 - Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
A61K 38/27 - Growth hormone [GH], i.e. somatotropin
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Pharmaceutical preparations for the treatment of neurological diseases and disorders; pharmaceutical preparations for the treatment of the symptoms of concussion; nutraceutical preparations for the treatment of neurological diseases and disorders; nutraceutical preparations for the treatment of the symptoms of concussion; nutritional supplements for general health and well-being; dietary supplements for general health and well-being; vitamin and mineral supplements
(2) Wearable electronic devices and computer hardware, namely, headsets and wearable activity trackers for neurological signal detection; Wearable electronic devices, namely, headsets and wearable activity trackers and computer hardware for capturing, tracking, processing and analyzing high speed digital images of the eye for use in assessing and improving human brain functions and potentials; Wearable electronic devices, namely, headsets and wearable activity trackers and computer hardware for use in the field of assessing and improving human brain functions and potentials; Wearable electronic devices, namely, headsets and wearable activity trackers that collect physical activity, eye activity, brain activity, and biometric data and communicate such data to personal digital assistants, tablets, smart phones, and personal computers wirelessly and through internet websites; Computer hardware and software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; downloadable applications for mobile phones for use in measuring and improving neurological health; downloadable application software for alerts, messages, emails, and reminders, and for receiving, recording, organizing, manipulating, reviewing, analyzing and transmitting neurological signal data, physical activity data, brain activity data, and biometric data; medical device, namely, a head mounted display for evaluating, diagnosing and treating vestibular and neurotologic disorders; medical device, namely, a video screen, digital signal and video processors, and headset, provided together as a kit for medical purposes, for evaluating, diagnosing and treating vestibular and neurotologic disorders;
(3) Apparatus for performing oculographic analysis, namely, video oculography, video nystagmography, and video frenzel systems; medical devices for diagnosing and measuring concussion; apparatus used in implementing diagnosis tests for vestibular and neurotologic disorders; (1) Non-downloadable computer software for displaying, aggregating, analyzing and organizing data and information in the field of neurological health; non-downloadable computer software for use in measuring and improving human brain functions and neurological health; non-downloadable computer software for the evaluation, diagnosis and treatment of vestibular and neurological disorders; non-downloadable computer software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; Software as a service (SaaS) for use in designing, creating and analyzing data, metrics and reports in the areas of brain health and neurological health;
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical preparations for the treatment of neurological diseases and disorders; pharmaceutical preparations for the treatment of the symptoms of concussion; nutraceutical preparations for the treatment of neurological diseases and disorders; nutraceutical preparations for the treatment of the symptoms of concussion.. Computer hardware and software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; computer hardware and software for capturing, tracking, processing and analyzing high speed digital images of the eye; downloadable applications for mobile phones for use in diagnosing and measuring concussion.. Apparatus for performing oculographic analysis including video oculography, video nystagmography, and video frenzel systems; medical devices for diagnosing and measuring concussion; apparatus used in implementing diagnosis tests for vestibular and neurotologic disorders; medical device, namely, a head mounted display for evaluating, diagnosing and treating vestibular and neurotologic disorders; medical device, namely, a video screen, processor, and headset, provided together as a kit, for evaluating, diagnosing and treating vestibular and neurotologic disorders.. Installation, maintenance, diagnosis and repair of medical diagnostic apparatus and instruments.. Computer software installation and maintenance; calibration of medical diagnostic apparatus and instruments; professional technical support services, namely, troubleshooting of computer software problems related to medical diagnostic apparatus and instruments; providing non-downloadable computer software for the evaluation, diagnosis and treatment of vestibular and neurotologic disorders; providing downloadable applications for mobile phones for use in diagnosing and measuring concussion..
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical preparations for the treatment of neurological diseases and disorders, namely, concussion, multiple sclerosis, dementia, mild cognitive impairment, Parkinson's disease, attention deficit hyperactivity disorder, Alzheimer's disease, strabismus and vestibular migraine; pharmaceutical preparations for the treatment of the symptoms of concussion; nutraceutical preparations for the treatment of neurological diseases and disorders, namely, concussion, multiple sclerosis, dementia, mild cognitive impairment, Parkinson's disease, attention deficit hyperactivity disorder, Alzheimer's disease, strabismus and vestibular migraine; nutraceutical preparations for the treatment of the symptoms of concussion Computer hardware and downloadable and recordable software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; computer hardware and downloadable and recordable software for capturing, tracking, processing and analyzing high speed digital images of the eye; downloadable software applications for mobile phones for use in diagnosing and measuring concussion Apparatus for performing oculographic analysis including video oculography, video nystagmography, and video frenzel systems; medical devices for diagnosing and measuring concussion; apparatus used in implementing diagnosis tests for vestibular and neurotologic disorders; medical device, namely, a head mounted display for evaluating, diagnosing and treating vestibular and neurotologic disorders; medical device, namely, a video screen, processor, and headset, provided together as a kit, for evaluating, diagnosing and treating vestibular and neurotologic disorders Installation, maintenance, diagnosis and repair of medical diagnostic apparatus and instruments Computer software installation and maintenance; calibration of medical diagnostic apparatus and instruments; professional technical support services, namely, troubleshooting of computer software problems related to medical diagnostic apparatus and instruments; providing temporary use of non-downloadable computer software for the evaluation, diagnosis and treatment of vestibular and neurotologic disorders
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
37 - Construction and mining; installation and repair services
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Pharmaceutical preparations for the treatment of neurological diseases and disorders; pharmaceutical preparations for the treatment of the symptoms of concussion; nutraceutical preparations for the treatment of neurological diseases and disorders; nutraceutical preparations for the treatment of the symptoms of concussion;
(2) Computer hardware and software for use in conducting and analyzing oculomotor, vestibular, reaction time and cognitive tests; computer hardware and software for capturing, tracking, processing and analyzing high speed digital images of the eye; downloadable applications for mobile phones for use in diagnosing and measuring concussion; medical device, namely, a head mounted display for evaluating, diagnosing and treating vestibular and neurotologic disorders; medical device, namely, a video screen, digital signal and video processors, and headset, provided together as a kit for medical purposes, for evaluating, diagnosing and treating vestibular and neurotologic disorders;
(3) Apparatus for performing oculographic analysis, namely, video oculography, video nystagmography, and video frenzel systems; medical devices for diagnosing and measuring concussion; apparatus used in implementing diagnosis tests for vestibular and neurotologic disorders; (1) Installation, maintenance, diagnosis and repair of medical diagnostic apparatus and instruments;
(2) Computer software installation and maintenance; calibration of medical diagnostic apparatus and instruments; professional technical support services, namely, troubleshooting of computer software problems related to medical diagnostic apparatus and instruments; providing non-downloadable computer software for the evaluation, diagnosis and treatment of vestibular and neurotologic disorders;
A system and associated method for computerized rotational head impulse test (crHIT) to assess the semicircular canals of the human vestibular system clinically in patients with balance disorders. The system utilizes a rotary chair combined with a head mounted VOG system with head tracking sensors. The crHIT protocol uses the same physiologic principles as the known video head impulse test (vHIT). The crHIT utilizes whole-body rotation via the chair to yield a persistent controlled, repeatable, comfortable, reliable stimulus can be delivered while recording eye movements with video-oculogaphy.
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
G02F 1/133 - Constructional arrangementsOperation of liquid crystal cellsCircuit arrangements
G02F 1/1335 - Structural association of cells with optical devices, e.g. polarisers or reflectors
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
G01J 1/42 - Photometry, e.g. photographic exposure meter using electric radiation detectors
9.
Objective testing of vergence dysfunction for using dynamic vergence testing platform including 3D head mounted display system with integrated eye tracking technology
An objective testing of vergence dysfunction comprising the steps of: providing a head mounted goggle based stimulus generating eye tracking unit to the subject; presenting visual stimulus to the subject, wherein the visual stimulus is in the head mounted goggle based system and forms the optical target stimulus for at least one vergence test; obtaining objective physiologic response of the subject from the head mounted goggle unit based upon each of the visual stimulus presented to the subject in each test; and using the objective physiologic responses to diagnose the presence of vergence dysfunction. On objective portable head mounted goggle based stimulus generating eye tracking unit for vergence testing is discloses as is a method of method of vergence recovery convalescence.
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
G02B 27/00 - Optical systems or apparatus not provided for by any of the groups ,
An objective screening platform for mTBI screening includes a vergence testing stimulus generator visible to a subject and configured for presenting visual stimulus to a subject which forms an optical target stimulus for at least one vergence test; at least one data acquisition unit for obtaining objective physiologic responses of the subject unit based upon each of the visual stimulus presented to the subject in each test, wherein the objective physiologic responses for each test include at least one eye position parameter and at least one pupil area parameter; and a controller configured for using at least one eye position parameter and at least one pupil area parameter to screen for the presence of mTBI of the subject.
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 3/08 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing binocular or stereoscopic vision, e.g. strabismus
A61B 90/50 - Supports for surgical instruments, e.g. articulated arms
11.
Apparatus and method for computerized rotational head impulse test
A system and associated method for computerized rotational head impulse test (crHIT) to assess the semicircular canals of the human vestibular system clinically in patients with balance disorders. The system utilizes a rotary chair combined with a head mounted VOG system with head tracking sensors. The crHIT protocol uses the same physiologic principles as the known video head impulse test (vHIT). The crHIT utilizes whole-body rotation via the chair to yield a persistent controlled, repeatable, comfortable, reliable stimulus can be delivered while recording eye movements with video-oculogaphy.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
G02F 1/133 - Constructional arrangementsOperation of liquid crystal cellsCircuit arrangements
G02F 1/1335 - Structural association of cells with optical devices, e.g. polarisers or reflectors
G01J 1/42 - Photometry, e.g. photographic exposure meter using electric radiation detectors
12.
Portable google based VOG system with comparative left and right eye ocular response analysis with MTBI analysis using percent of saccade function of smooth pursuit test
A head mounted compact goggle based video oculography system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.
A61B 3/06 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient for testing light sensitivity, e.g. adaptationSubjective types, i.e. testing apparatus requiring the active assistance of the patient for testing colour vision
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
13.
Head mounted compact goggle based video oculography system with integral stimulus screen
A head mounted compact goggle based video oculography system is configured for use in VOG-based neuro-otologic testing. The system comprises: a goggle base surrounding the subject's eyes; an angled hot mirror within the goggle base; at least one digital camera attached to the goggle base along the top side of the goggle base taking images of at least one of the subject's eyes via a hot mirror reflection; an integral display for selectively displaying visual stimulus to the subject through the hot mirror and attached to the goggle base along the rear side of the goggle base; a controller coupled to the display generating each visual stimulus for each neuro-otologic test to be displayed to the subject via the display and coupled to each digital camera and receiving and storing data signals there from, the controller configured to calculate eye related data from the digital camera images during each neuro-otologic test, and configured to display the eye related data to users.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
14.
Method of measuring and analyzing ocular response in a subject using stable pupillary parameters with video oculography system
A method of measuring and analyzing an ocular response in a subject comprising the steps of: Providing a video oculography based system for the subject with the system configured to collect eye images in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one stimulus is presented to only one eye of the subject and configured to yield a pupil eye response from at least one eye of the subject; Calculating pupilometry measurements from the eye data, wherein the pupil measurements are calculated independently for the subject's left and right eyes for each stimulus presented to the subject, and wherein comparative left and right pupilometry measurements from the eye data are calculated; analyzing a subject's ocular response based upon at least one of the calculated pupilometry measurements.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
15.
Noninvasive rapid screening of mild traumatic brain injury using combination of subject's objective oculomotor, vestibular and reaction time analytic variables
A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 5/16 - Devices for psychotechnicsTesting reaction times
A video oculography (VOG) system for calculation and display of Corrective Secondary Saccades Analysis is disclosed and utilized in a method for Objective Diagnostics of Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy and Glissades. The method comprises the steps of using a VOG system to calculate corrective saccades. The VOG based system is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion and collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy are calculated.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
17.
Method and associated apparatus for detecting minor traumatic brain injury
Minor traumatic brain injury is detected by operating (a) an image generator for presenting a visual stimulus having a predetermined movement across a visual field of a subject and (b) a sensor device for monitoring fast eye movement of the subject while the subject views the stimulus. The sensor device generates a signal encoding the subject's eye position. A computer or microprocessor operatively connected to the sensor device is configured for determining a magnitude for the fast eye velocity component.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 5/16 - Devices for psychotechnicsTesting reaction times
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
18.
Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic optokinetic testing
A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol including optokinetic testing that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
19.
Method corrective secondary saccades analysis with video oculography system for objective diagnostic of traumatic brain injury, internuclear opthalmopligia, ocular lateral pulsion and progressive supernuclear palsy and glissades
A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
20.
Method and apparatus for validating testing procedures in objective ophthalmic eye testing for eye evaluation applications requiring subject compliance with eye fixation to a visual target
A method and associated apparatus for validating testing procedure in objective ophthalmic eye testing is implemented for eye evaluation applications requiring subject compliance with eye fixation to a visual target. The method comprises the steps of: supplying a predetermined visual fixation target to the subject in a predetermined location with an automated ophthalmic eye testing device, wherein the testing procedure of the eye evaluation application requires the subject to fixate upon the visual fixation stimulus; tracking the subject's gaze during at least the supplying of the predetermined visual fixation stimulus to the subject throughout the testing procedure of the eye evaluation application with a video based eye tracking system; and validating the testing procedure by at least one of i) indicating to the clinician when the subject's gaze location differs from the predetermined visual fixation stimulus by an amount greater than a predetermined threshold amount, and ii) having the automated ophthalmic eye testing device repeat at least portions of the testing procedures when the subject's gaze location differs from the predetermined visual fixation stimulus by an amount greater than a predetermined threshold amount.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
21.
Method and apparatus for system synchronization in video oculography based neuro-otologic testing and evaluation
A video oculography based neuro-otologic testing and evaluation apparatus and associated method comprises the steps of: Obtaining images of the subject's eyes with a digital camera; Selectively displaying visual stimulus to the subject on a display; Generating each visual stimulus to be displayed from a controller; Receiving and storing data signals from each digital camera in the controller; Calculating eye related data from the digital camera images and visual stimulus; Displaying the eye related data to users; Generating a video synchronization signal by the controller associated with each visual stimulus which identifies when the display is displaying the associated visual stimulus; Receiving and coupling the video synchronization signal with at least the eye data from the digital camera; and Synchronizing calculations based upon the eye data and the visual stimulus by the controller.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
22.
Method of measuring and analyzing ocular response in a subject using stable pupillary parameters with video oculography system
A method of measuring and analyzing an ocular response in a subject comprising the steps of: Providing a video oculography based system for the subject with the system configured to collect eye images in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion; Collecting eye data with the video oculography based system wherein at least one stimulus is presented to only one eye of the subject and configured to yield a pupil eye response from at least one eye of the subject; Calculating pupilometry measurements from the eye data, wherein the pupil measurements are calculated independently for the subject's left and right eyes for each stimulus presented to the subject, and wherein comparative left and right pupilometry measurements from the eye data are calculated; analyzing a subject's ocular response based upon at least one of the calculated pupilometry measurements.
A61B 3/00 - Apparatus for testing the eyesInstruments for examining the eyes
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/11 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for measuring interpupillary distance or diameter of pupils
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/02 - Subjective types, i.e. testing apparatus requiring the active assistance of the patient
23.
Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using VOG device for neurologic testing
A portable VOG device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
A61B 3/032 - Devices for presenting test symbols or characters, e.g. test chart projectors
24.
Method and apparatus for corrective secondary saccades analysis with video oculography system
A video oculography system for calculation and display of Corrective Secondary Saccades Analysis is disclosed. A method for Objective Diagnostics of at least one of traumatic brain injury, Internuclear Opthalmopligia, Ocular Lateral Pulsion, Progressive Supernuclear Palsy And Glissades comprises the steps of using a VOG system to calculate corrective saccades. The video oculography based system for the subject is configured to collect eye images of the patient in excess of 60 hz and configured to resolve eye movements smaller than at least 3 degrees of motion. The video oculography based system collects eye movement data wherein at least one fixation target is presented to the subject in a defined position configured to yield a voluntary saccadic eye response from at least one eye of the patient. The latency, amplitude, accuracy and velocity of each respective corrective saccade and totals latency and accuracy is calculated.
In the field of eye tracking, greater accuracy or resolution in monitoring movement of the eye can be gained by digitizing the eye, and tracking the movement of a landmark with fixed size and a fixed location relative to the eye's local coordinate system. The edge of the iris can be used as such a fixed landmark. Through the location and or establishment of at least a portion of the outer edge of the iris and/or an iris center point, both large and small scale eye movements, including but not limited to micro-tremors, can be traced with a higher degree of accuracy. This will aid in the diagnosis of diseases, assessing state of consciousness, and defining brainstem death.
G06K 9/00 - Methods or arrangements for reading or recognising printed or written characters or for recognising patterns, e.g. fingerprints
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
26.
Quantitative, non-invasive, clinical diagnosis of traumatic brain injury using simulated distance visual stimulus device for neurologic testing
A portable virtual reality device is disclosed that will facilitate the effective and efficient screening for TBI in military personnel in forward deployed military settings or remote locations using minimally trained staff. This includes the establishment of a protocol that will provide cost effective pre-screening of military personnel prior to deployment to establish a baseline of brain function prior to possible future injury. The efficiency of the device will promote subsequent follow-up screening to assess the effectiveness of prescribed TBI treatment. Further protocols for diagnosis and rehabilitation applications using the same virtual reality portable device will allow more advanced usage for clinicians providing ongoing evaluation and treatment.
A goggle based light-weight VOG/EOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection. The EOG system is incorporated directly into a goggle base. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. The VOG system may track and record 3-D movement of the eye, track pupil dilation, head position and goggle slippage. An animated eye display provides data in a more meaningful fashion. The VOG system is a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.
A61B 3/14 - Arrangements specially adapted for eye photography
A61B 3/113 - Objective types, i.e. instruments for examining the eyes independent of the patients perceptions or reactions for determining or recording eye movement
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Compact neuro-otologic, neuro-ophthalmologic testing device and dynamic visual acuity testing and desensitization platform
2 and at velocities in excess of 12000 degrees/second. The bandwidth of the XY interface is greater than 400 Hz, providing high image reproducibility. The repeatability and position accuracy of the target is +−3 arc-seconds and the field of range of the XY interface are about 60 degrees (i.e. about 60 degrees horizontal and 60 degrees vertical).
A goggle based light-weight VOG system includes at least one digital camera connected to and powered by a laptop computer through a firewire connection. The digital camera may digitally center the pupil in both the X and Y directions. A calibration mechanism may be incorporated onto the goggle base. An EOG system may also be incorporated directly into the goggle. The VOG system may track and record 3-D movement of the eye, track pupil dilation, head position and goggle slippage. An animated eye display provides data in a more meaningful fashion. The VOG system is a modular design whereby the same goggle frame or base is used to build a variety of digital camera VOG systems.
Video-Occulography System for tracking patient eye movement, comprised of a video camera for obtaining eye and other physiologic image data, a camera mounting unit, a processing unit for processing the physiologic video data, and a display for displaying the processed pysiologic data