Abstract

The present invention relates to the use of botulinum toxin for the treatment of hyperpigmentation conditions. The use comprises the intradermal injection of botulinum toxin in the skin of a patient affected with the hyperpigmentation condition at a specified depth, volume and dose, thereby specifically targeting the epidermal and upper dermal layers. For example, the intradermal injection of botulinum toxin according to the present invention may be used in the treatment of melasma.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 8/66 - Enzymes
• A61K 8/99 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61Q 19/02 - Preparations for care of the skin for chemically bleaching or whitening the skin

Goods & Services

Computer hardware for visualizing skin tissue in the fields of aesthetics and dermatology; downloadable fact sheets in the field of aesthetics and dermatology; downloadable medical software for visualizing skin tissue in the fields of aesthetics and dermatology; recorded medical software for visualizing skin tissue in the fields of aesthetics and dermatology; user interfaces, namely, touchscreens for electrotechnical and electronic devices. Cosmetic apparatus using ultrasound for performing aesthetic skin treatment procedures; medical apparatus for use in treating dermatological disorders; medical devices for nonsurgical cosmetic treatments. Printed educational materials in the field of aesthetics and dermatology; printed training materials in the field of aesthetics and dermatology. Cosmetic skin care services; dermatology services; providing information in the field of medical aesthetics and dermatological health via a web site.

Abstract

Embodiments of a dermatological cosmetic treatment and imaging system and method can include use of transducer to simultaneously or substantially simultaneously produce multiple cosmetic treatment zones in tissue. The system can include a hand wand, a removable transducer module, a control module, and/or graphical user interface. In some embodiments, the cosmetic treatment system may be used in cosmetic procedures, including brow lifts, fat reduction, sweat reduction, and treatment of the décolletage. Skin tightening, lifting and amelioration of wrinkles and stretch marks are provided.

IPC Classes  ?

• A61N 7/00 - Ultrasound therapy
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
• A61N 7/02 - Localised ultrasound hyperthermia

Goods & Services

Computer hardware for visualizing skin tissue using ultrasound; Downloadable fact sheets in the field of beauty care; Downloadable medical software for visualizing skin tissue using ultrasound; Recorded medical software for visualizing skin tissue using ultrasound; User interfaces for electronic visualization devices; Computer hardware for Ultrasonic imaging apparatus Devices for aesthetic skin treatment; Aesthetic skin treatment apparatus using ultrasound; Aesthetic device using ultrasound for performing treatment procedures; Medical ultrasound instruments and apparatus; Probes for use in treating dermatological conditions; Devices for cosmetic treatments; Ultrasonic imaging apparatus for medical purposes; Medical imaging apparatus On-line video journals, namely, vlogs featuring non downloadable videos in the field of aesthetics, dermatology and medicine; Providing a website featuring blogs and non downloadable publications in the nature of articles in the field(s) of aesthetics, dermatology and medicine; Training services in the field of aesthetics, dermatology, and medicine Printed educational materials in the field of beauty care; Printed training materials in the field of beauty care · Cosmetic treatment; Aesthetic skin care services; Non-invasive cosmetic ultrasound procedures, namely for skin tightening, skin firming and skin lifting; Providing information about health and wellness, namely, aesthetics and dermatology; Med spa and beauty care services; Providing a website featuring information in the field of beauty care; Medical skin care services; Non-invasive medical ultrasound procedures, namely, for skin tightening, skin firming and skin lifting

Goods & Services

Pharmaceutical products, namely, pharmaceutical and biological preparations used in the treatment of spinal cord injuries, multiple sclerosis and other diseases, disorders or conditions of the nervous system

Goods & Services

Providing campaigns featuring information to promote public awareness regarding Parkinson's disease; excluding information technology services in the form of artificial intelligence or automated voice-response Providing health information regarding Parkinson's disease; excluding information technology services in the form of artificial intelligence or automated voice-response

Abstract

Embodiments of a dermatological cosmetic treatment and/or imaging system and method adapted to alter placement and position of multiple cosmetic treatment zones in tissue from ultrasound beams from a transducer, simultaneous multi-focus therapy at multiple depths, and/or dithering ultrasound beams from a transducer to alter placement and position of multiple cosmetic treatment zones in tissue. The system can include a hand wand, a removable transducer module, and a control module. In some embodiments, the cosmetic treatment system may be used in various cosmetic procedures.

IPC Classes  ?

• A61N 7/02 - Localised ultrasound hyperthermia
• A61N 7/00 - Ultrasound therapy

Abstract

The invention proposes a method for preparing a cross-linked material, comprising forming amide bonds that conjugate one or more fibroin moieties with one or more polysaccharide moieties. The invention further relates to a cross-linked material obtainable from such method and to an injectable composition comprising the obtained cross-linked material. The cross-linked material can be a hydrogel and/or a super-volumizer and can be used in cosmetic and pharmaceutical applications.

IPC Classes  ?

• C08B 37/08 - Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
• A61L 27/22 - Polypeptides or derivatives thereof
• A61L 27/52 - Hydrogels or hydrocolloids
• C07K 14/435 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans

Abstract

The present invention relates to a dermal filler composition based on crosslinked hyaluronic acid, wherein the hyaluronic acid is crosslinked with a high molecular weight polyethylene glycol diglycidyl ether (PEGDE) crosslinker having an average number of —CH2—CH2—O— repetitive units of 8 to 90. Furthermore, the present invention relates to a method for preparing said dermal filler composition and its use for cosmetic purposes.

IPC Classes  ?

• A61L 27/26 - Mixtures of macromolecular materials
• A61K 8/73 - Polysaccharides
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• A61Q 19/08 - Anti-ageing preparations

Goods & Services

Ultrasonic imaging apparatus, not for medical purposes; computer hardware for visualizing tissue in the fields of aesthetics and dermatology; downloadable fact sheets in the field of aesthetics and dermatology; downloadable medical software for visualizing tissue in the fields of aesthetics and dermatology; recorded medical software for visualizing tissue in the fields of aesthetics and dermatology; user interfaces, namely touchscreens for electrotechnical and electronic devices. Devices, apparatus and instruments for aesthetic tissue treatment; aesthetic tissue treatment apparatus using ultrasound; cosmetic apparatus using ultrasound for performing aesthetic tissue treatment procedures; medical instruments and apparatus; medical ultrasound instruments and apparatus; medical instruments and apparatus for use in treating dermatological disorders; medical devices for non-surgical cosmetic treatments; ultrasonic imaging apparatus for medical purposes; medical imaging apparatus. Aesthetician services; cosmetic treatment; cosmetic skin care and tissue treatment services; non-invasive cosmetic ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; providing information about health and wellness, namely, aesthetics and dermatology; medical and cosmetic ultrasound imaging services; medical services; medical skin care services; medical services, namely ultrasound treatment; medical services, namely dermatological treatment; non-invasive medical ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; providing medical information in the field of medical skin care services; providing medical advice in the field of medical ultrasound imaging services.

Abstract

A rocking shaker (110) for treating at least one fluid sample is disclosed. The rocking shaker (110) comprises: i. at least one mechanical frame (112), the mechanical frame (112) comprising at least one tilting axle (114); ii. at least one mounting platform (128) being tiltably mounted on the tilting axle (114), the mounting platform (128) being configured for receiving at least one sample holder; iii. at least one actuator (136), the actuator (136) being configured for periodically tilting the mounting platform (128) about the tilting axle (114) over an angular orientation range; and iv. at least one driving circuit (220) for electrically driving the actuator (136), the driving circuit (220) comprising at least one switch-off device (222), the switch-off device (222) being configured for automatically bringing the mounting platform (128) in a predetermined switch-off orientation when the rocking shaker (110) is switched off.

IPC Classes  ?

• B01F 31/23 - Mixing the contents of independent containers, e.g. test tubes by pivoting the containers about an axis
• B01F 31/00 - Mixers with shaking, oscillating, or vibrating mechanisms
• B01F 35/222 - Control or regulation of the position of mixing devices or elements
• B01F 33/25 - Mixers with loose mixing elements, e.g. loose balls in a receptacle

Abstract

The invention pertains to a method for directly determining the biological activity of a Neurotoxin polypeptide in cells, comprising the steps of: a) incubating cells susceptible to Neurotoxin intoxication with a Neurotoxin polypeptide for a time and under conditions which allow for the Neurotoxin polypeptide to exert its biological activity; b) fixing the cells and, optionally, permeabilizing the cells with a detergent; c) contacting the cells with at least a first capture antibody specifically binding to the non-cleaved and Neurotoxin-cleaved substrate and with at least a second capture antibody specifically binding to the cleavage site of the Neurotoxin-cleaved substrate, under conditions which allow for binding of the capture antibodies to the substrates; d) contacting the cells with at least a first detection antibody specifically binding to the first capture antibody, under conditions which allow for binding of the first detection antibody to the first capture antibody, thus forming first detection complexes, and at least a second detection antibody specifically binding to the second capture antibody, under conditions which allow for binding of the second detection antibody to the second capture antibody, thus forming second detection complexes; e) determining the amount of the first and second detection complexes of step d), and f) calculating the amount of substrate cleaved by the Neurotoxin polypeptide in the cells by means of the second detection complexes, thereby determining the biological activity of the Neurotoxin polypeptide in the cells. The invention further provides for a kit for carrying out the method of the invention.

IPC Classes  ?

• C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
• G01N 21/64 - Fluorescence; Phosphorescence
• G01N 33/50 - Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Goods & Services

Online publication of journals or diaries [weblog services], featuring non-downloadable videos in the field of aesthetics, dermatology and medicine; publications of electronic books and journals online in the fields of aesthetics, dermatology and medicine; training services in the field of aesthetics, dermatology and medicine. Dermatology services; providing medical information via a website; providing medical information in the field of aesthetic body care services and dermatological health via a website.

Goods & Services

Pharmaceutical preparations, namely a preparation for treatment of liver diseases; nutritional supplements for the liver.

Abstract

The present invention concerns a composition comprising (a) botulinum toxin and (b) non-crosslinked hyaluronic acid and its use of the treatment or prevention of dystonia, spasticity and/or wrinkles. Further, the present invention relates to a method for cosmetically smoothing or preventing wrinkles comprising the step of administering the present composition.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 8/64 - Proteins; Peptides; Derivatives or degradation products thereof
• A61K 8/73 - Polysaccharides
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/08 - Solutions
• A61K 47/36 - Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
• A61Q 19/08 - Anti-ageing preparations

Abstract

Ultrasound devices, and associated methods of assembly thereof, are disclosed whereby an annular electrode array of an ultrasound transducer is electrically connected to a flexible printed circuit board in a compact configuration. The flexible circuit board includes an elongate flexible segment and a distal distribution segment, where the distribution segment is attached to a peripheral support ring that surrounds at least a portion of the ultrasound transducer. The distribution segment includes a plurality of spatially distributed contact pads, and electrical connections are provided between the contact pads and the annular electrodes of the annular array. A backing material may be provided that contacts and extends from the annular array electrodes, and a distal portion of the elongate flexible segment may be encapsulated in the backing material, such that the distal portion extends inwardly from the peripheral support ring, without contacting the electrical connections and without contacting the array surface.

IPC Classes  ?

• B06B 1/06 - Processes or apparatus for generating mechanical vibrations of infrasonic, sonic or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction

Abstract

The present invention relates to a syringe barrel having an interior surface coated with a silicone film having a thickness in the range of 5 nm to 100 nm. It further relates to a method for manufacturing said syringe barrel comprising the step of reducing an initial thickness of a pre-formed silicone film on the interior surface of a syringe barrel to a thickness within the range of about 5 nm to about 100 nm by exposing the syringe barrel to an organic solvent or by subjecting the syringe barrel to mechanical treatment. Furthermore, the present invention relates to a syringe comprising the syringe barrel of the invention, a kit comprising said syringe, and cosmetic and therapeutic uses of said syringe.

IPC Classes  ?

• A61M 5/31 - Syringes - Details
• A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing

Abstract

Enhancements of resolution of high speed ultrasound imaging of tissue in association with aesthetic and/or cosmetic treatments of skin and/or tissue near the skin. In one embodiment, high resolution ultrasound imaging uses dynamic focal zone blending to reduce an appearance of acoustic window multipath echo artifacts. In one embodiment, high resolution ultrasound imaging uses an offset between a first imaging frame in a first direction and a second imaging frame in a second direction to reduce a temporal motion artifact. In some embodiments, the imaging system is used with an aesthetic and/or cosmetic skin treatment.

IPC Classes  ?

• A61B 8/08 - Detecting organic movements or changes, e.g. tumours, cysts, swellings
• A61B 8/06 - Measuring blood flow

Abstract

A device for puncturing a capsule to release a powdered medicament therefrom includes a chamber for receiving the capsule. The capsule includes opposing domes and a cylindrical wall portion defined by a capsule wall radius r. The device further includes a mechanism for puncturing at least one hole in at least one dome. A center of each hole is located within an annular puncture region situated at no less than 0.4 r, and a total surface area of all puncture holes is between about 0.5% and about 2.2% of a total surface area of the capsule. The annular puncture region may, for example, be situated between about 0.4 r and about 0.8 r, or between about 0.4 r and about 0.6 r.

IPC Classes  ?

• A61M 15/00 - Inhalators

Abstract

Dermatological cosmetic combination treatments with high intensity focused ultrasound, dermal fillers, fat-reducing compounds, cavitation-prone fluids, and/or septa dissection are provided. A HIFU therapy system can include an imaging system, methods adapted to alter placement and position of a line focus, multiple simultaneous cosmetic ultrasound treatment zones and/or dithering ultrasound beams from a transducer to alter placement and position of multiple cosmetic treatment zones in tissue. The HIFU systems can include a hand wand removable transducer module, and control module. The dermal fillers can include hydroxyapatite. The fat-reducing compounds can include adipocytolytic compounds, pentacyclic triterpenoid compounds, proapoptotic compounds, compounds impairing differentiation of pre-adipocytes, and combinations thereof. The cavitation-prone fluids can include molecules dissolved in fluids, ethanol, glycerin, and ethylene glycol. The septa dissecting can include using a cutting blade and/or cavitation HIFU. The cosmetic treatment system may be used in various cosmetic procedures, such as treating cellulite.

IPC Classes  ?

• A61N 7/02 - Localised ultrasound hyperthermia
• A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
• A61N 7/00 - Ultrasound therapy

Abstract

The present invention relates to a composition comprising (A) a cross-linked material comprising one or more fibroin moieties and one or more polysaccharide moieties covalently conjugated with each other, (B) botulinum toxin. Furthermore, the present invention relates to therapeutic and aesthetic uses of such composition.

IPC Classes  ?

• A61K 8/64 - Proteins; Peptides; Derivatives or degradation products thereof
• A61K 8/73 - Polysaccharides
• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 47/36 - Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61Q 19/00 - Preparations for care of the skin

Abstract

The present invention generally relates to the use of botulinum toxin for lower face and neck rejuvenation by injection of highly concentrated botulinum toxin into platysma, more specifically into platysma bands and the platysma muscle at the jawline. Specifically, the botulinum toxin is injected in the platysma bands and the platysma muscle at the jawline at a dose of 3 U to 5 U and a volume of 0.04 ml to 0.06 ml per injection point. Furthermore, the present invention relates to a method for lower face and neck rejuvenation comprising injection of botulinum toxin in platysma bands and in the platysma muscle at the jawline at a dose of 3 U to 5 U and a volume of 0.04 ml to 0.06 ml per injection point.

IPC Classes  ?

• A61K 8/64 - Proteins; Peptides; Derivatives or degradation products thereof
• A61Q 19/00 - Preparations for care of the skin

Abstract

The present invention generally relates to the use of botulinum toxin for neck rejuvenation by injection of highly concentrated botulinum toxin into the platysma muscle. Specifically, the botulinum toxin is injected in at least one platysma band of a subject at a concentration of more than 100 U/ml. Furthermore, the present invention relates to a method for neck rejuvenation involving injection of botulinum toxin at high concentration.

IPC Classes  ?

• A61Q 19/08 - Anti-ageing preparations
• A61K 8/66 - Enzymes

Goods & Services

Ultrasonic imaging apparatus, not for medical purposes; Computer hardware for visualizing tissue in the fields of aesthetics and dermatology; downloadable fact sheets in the field of aesthetics and dermatology; downloadable medical software for visualizing tissue in the fields of aesthetics and dermatology; recorded medical software for visualizing tissue in the fields of aesthetics and dermatology; user interfaces, namely touchscreens for electrotechnical and electronic devices. Devices, apparatus and instruments for aesthetic tissue treatment; Aesthetic tissue treatment apparatus using ultrasound; Cosmetic apparatus using ultrasound for performing aesthetic tissue treatment procedures; Medical instruments and apparatus; Medical ultrasound instruments and apparatus; Medical instruments and apparatus for use in treating dermatological disorders; Medical devices for non-surgical cosmetic treatments; Ultrasonic imaging apparatus for medical purposes; Medical imaging apparatus. Aesthetician services; Cosmetic treatment; Cosmetic skin care and tissue treatment services; Non-invasive cosmetic ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing information about health and wellness, namely, aesthetics and dermatology; Medical and cosmetic ultrasound imaging services; Medical services; Medical skin care services; Medical services, namely ultrasound treatment; Medical services, namely dermatological treatment; Non-invasive medical ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing medical information in the field of medical skin care services; Providing medical advice in the field of medical ultrasound imaging services.

Goods & Services

Ultrasonic imaging apparatus, not for medical purposes; Computer hardware for visualizing tissue in the fields of aesthetics and dermatology; downloadable fact sheets in the field of aesthetics and dermatology; downloadable medical software for visualizing tissue in the fields of aesthetics and dermatology; recorded medical software for visualizing tissue in the fields of aesthetics and dermatology; user interfaces, namely touchscreens for electrotechnical and electronic devices. Devices, apparatus and instruments for aesthetic tissue treatment; Aesthetic tissue treatment apparatus using ultrasound; Cosmetic apparatus using ultrasound for performing aesthetic tissue treatment procedures; Medical instruments and apparatus; Medical ultrasound instruments and apparatus; Medical instruments and apparatus for use in treating dermatological disorders; Medical devices for non-surgical cosmetic treatments; Ultrasonic imaging apparatus for medical purposes; Medical imaging apparatus. Aesthetician services; Cosmetic treatment; Cosmetic skin care and tissue treatment services; Non-invasive cosmetic ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing information about health and wellness, namely, aesthetics and dermatology; Medical and cosmetic ultrasound imaging services; Medical services; Medical skin care services; Medical services, namely ultrasound treatment; Medical services, namely dermatological treatment; Non-invasive medical ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing medical information in the field of medical skin care services; Providing medical advice in the field of medical ultrasound imaging services.

Goods & Services

Ultrasonic imaging apparatus, not for medical purposes; Computer hardware for visualizing tissue in the fields of aesthetics and dermatology; downloadable fact sheets in the field of aesthetics and dermatology; downloadable medical software for visualizing tissue in the fields of aesthetics and dermatology; recorded medical software for visualizing tissue in the fields of aesthetics and dermatology; user interfaces, namely touchscreens for electrotechnical and electronic devices. Devices, apparatus and instruments for aesthetic tissue treatment; Aesthetic tissue treatment apparatus using ultrasound; Cosmetic apparatus using ultrasound for performing aesthetic tissue treatment procedures; Medical instruments and apparatus; Medical ultrasound instruments and apparatus; Medical instruments and apparatus for use in treating dermatological disorders; Medical devices for non-surgical cosmetic treatments; Ultrasonic imaging apparatus for medical purposes; Medical imaging apparatus.

Goods & Services

Ultrasonic imaging apparatus, not for medical purposes; Computer hardware for visualizing tissue in the fields of aesthetics and dermatology; downloadable fact sheets in the field of aesthetics and dermatology; downloadable medical software for visualizing tissue in the fields of aesthetics and dermatology; recorded medical software for visualizing tissue in the fields of aesthetics and dermatology; user interfaces, namely touchscreens for electrotechnical and electronic devices. Devices, apparatus and instruments for aesthetic tissue treatment; Aesthetic tissue treatment apparatus using ultrasound; Cosmetic apparatus using ultrasound for performing aesthetic tissue treatment procedures; Medical instruments and apparatus; Medical ultrasound instruments and apparatus; Medical instruments and apparatus for use in treating dermatological disorders; Medical devices for non-surgical cosmetic treatments; Ultrasonic imaging apparatus for medical purposes; Medical imaging apparatus. Aesthetician services; Cosmetic treatment; Cosmetic skin care and tissue treatment services; Non-invasive cosmetic ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing information about health and wellness, namely, aesthetics and dermatology; Medical and cosmetic ultrasound imaging services; Medical services; Medical skin care services; Medical services, namely ultrasound treatment; Medical services, namely dermatological treatment; Non-invasive medical ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing medical information in the field of medical skin care services; Providing medical advice in the field of medical ultrasound imaging services.

Goods & Services

Ultrasonic imaging apparatus, not for medical purposes; Computer hardware for visualizing tissue in the fields of aesthetics and dermatology; downloadable fact sheets in the field of aesthetics and dermatology; downloadable medical software for visualizing tissue in the fields of aesthetics and dermatology; recorded medical software for visualizing tissue in the fields of aesthetics and dermatology; user interfaces, namely touchscreens for electrotechnical and electronic devices. Devices, apparatus and instruments for aesthetic tissue treatment; Aesthetic tissue treatment apparatus using ultrasound; Cosmetic apparatus using ultrasound for performing aesthetic tissue treatment procedures; Medical instruments and apparatus; Medical ultrasound instruments and apparatus; Medical instruments and apparatus for use in treating dermatological disorders; Medical devices for non-surgical cosmetic treatments; Ultrasonic imaging apparatus for medical purposes; Medical imaging apparatus. Aesthetician services; Cosmetic treatment; Cosmetic skin care and tissue treatment services; Non-invasive cosmetic ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing information about health and wellness, namely, aesthetics and dermatology; Medical and cosmetic ultrasound imaging services; Medical services; Medical skin care services; Medical services, namely ultrasound treatment; Medical services, namely dermatological treatment; Non-invasive medical ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing medical information in the field of medical skin care services; Providing medical advice in the field of medical ultrasound imaging services.

Goods & Services

Ultrasonic imaging apparatus, not for medical purposes; Computer hardware for visualizing tissue in the fields of aesthetics and dermatology; downloadable fact sheets in the field of aesthetics and dermatology; downloadable medical software for visualizing tissue in the fields of aesthetics and dermatology; recorded medical software for visualizing tissue in the fields of aesthetics and dermatology; user interfaces, namely touchscreens for electrotechnical and electronic devices. Devices, apparatus and instruments for aesthetic tissue treatment; Aesthetic tissue treatment apparatus using ultrasound; Cosmetic apparatus using ultrasound for performing aesthetic tissue treatment procedures; Medical instruments and apparatus; Medical ultrasound instruments and apparatus; Medical instruments and apparatus for use in treating dermatological disorders; Medical devices for non-surgical cosmetic treatments; Ultrasonic imaging apparatus for medical purposes; Medical imaging apparatus. Aesthetician services; Cosmetic treatment; Cosmetic skin care and tissue treatment services; Non-invasive cosmetic ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing information about health and wellness, namely, aesthetics and dermatology; Medical and cosmetic ultrasound imaging services; Medical services; Medical skin care services; Medical services, namely ultrasound treatment; Medical services, namely dermatological treatment; Non-invasive medical ultrasound procedures, namely for skin tightening, skin firming, skin sculpting, and skin lifting; Providing medical information in the field of medical skin care services; Providing medical advice in the field of medical ultrasound imaging services.

Abstract

The invention relates to calcium hydroxyapatite particles having been sintered at a certain temperature range and which are not treated at a temperature above this range. Furthermore, the present invention relates to an injectable composition comprising such particles and to uses thereof. Surprisingly, it was found that the particles of the invention are superior over calcium hydroxyapatite particles known in the art with respect to bio-stimulation.

IPC Classes  ?

• A61K 8/24 - Phosphorus; Compounds thereof
• A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 33/42 - Phosphorus; Compounds thereof
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61Q 19/08 - Anti-ageing preparations
• C01B 25/32 - Phosphates of magnesium, calcium, strontium, or barium

Abstract

The invention provides respirable dry powder particle formulations comprising polynucleotides preferably prepared by spray drying for delivery to the pulmonary system via inhalation. Preferably, the polynucleotide is RNA.

IPC Classes  ?

• A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
• A61K 9/16 - Agglomerates; Granulates; Microbeadlets

Goods & Services

Medical devices for nonsurgical cosmetic treatments; Medical ultrasound apparatus; Cosmetic apparatus using ultrasound for performing aesthetic skin treatment procedures; Medical apparatus for use in treating dermatological disorders; Medical instruments for use in treating tissue below a skin surface. Beauty spa services, namely, cosmetic body care; Cosmetic skin care services; Dermatology services; Medical services; Providing a web site featuring medical information; Providing a website featuring information in the field of aesthetics and dermatological health.

Goods & Services

(1) Medical ultrasound apparatus (2) Medical devices for nonsurgical cosmetic treatments; Cosmetic apparatus using ultrasound for performing aesthetic skin treatment procedures; Medical apparatus for use in treating dermatological disorders; Medical instruments for use in treating tissue below a skin surface. (1) Cosmetic skin care services; dermatology services (2) Beauty spa services, namely, cosmetic body care; Medical services; Providing a web site featuring medical information; Providing a website featuring information in the field of aesthetics and dermatological health.

Goods & Services

(1) Medical ultrasound apparatus (2) Medical devices for nonsurgical cosmetic treatments; Cosmetic apparatus using ultrasound for performing aesthetic skin treatment procedures; Medical apparatus for use in treating dermatological disorders; Medical instruments for use in treating tissue below a skin surface. (1) Cosmetic skin care services; dermatology services (2) Beauty spa services, namely, cosmetic body care; Medical services; Providing a web site featuring medical information; Providing a website featuring information in the field of aesthetics and dermatological health.

Abstract

The present invention is directed respirable, dry powder particle formulations of lung surfactants that optionally comprise surfactant proteins and that are formulated for delivery to the pulmonary system via inhalation.

IPC Classes  ?

• A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/14 - Particulate form, e.g. powders
• A61K 47/02 - Inorganic compounds
• A61K 47/10 - Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
• A61K 47/12 - Carboxylic acids; Salts or anhydrides thereof
• A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61K 47/36 - Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 47/42 - Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
• C07K 14/785 - Alveolar surfactant peptides; Pulmonary surfactant peptides

Abstract

The present invention relates to a method for restoring cell cycle and proliferative competence in resting cells and/or stimulating proliferation of cells, wherein said method comprises the step of contacting the cells with calcium hydroxyapatite particles having a mean particle diameter of from 1 to 500 μm, as determined by light scattering. Furthermore, the present invention refers to such calcium hydroxyapatite particles for use in a method for treating or preventing a pathologic condition associated with arrested cell cycle, decreased proliferative competence, decreased proliferation rate, or a combination of two or more thereof, and the use thereof as anti-aging agent.

IPC Classes  ?

• A61K 8/24 - Phosphorus; Compounds thereof
• A61K 8/02 - Cosmetics or similar toiletry preparations characterised by special physical form
• A61Q 19/08 - Anti-ageing preparations

Goods & Services

Shaving apparatus, electric and non-electric; depilation appliances, electric and non-electric. Heating appartus for waxing and depilation; heating apparatus for warming wax, and spatulas with integrated heating apparatus for applying wax to the skin.

Goods & Services

Downloadable fact sheets in the field of aesthetics and dermatology; Downloadable graphical user interface software for electronic devices Providing online nondownloadable videos in the fields of skin care, cosmetic procedures, ultrasound imaging, and ultrasound treatment; Providing a website featuring blogs and nondownloadable publications in the nature of articles, brochures, fact sheets, and newsletters in the fields of skin care, cosmetic procedures, medical devices, ultrasound imaging, and ultrasound treatment; Training services in the fields of skin care, cosmetic procedures, medical devices, ultrasound imaging, and ultrasound treatment Providing a website featuring information about skin care, cosmetic procedures, ultrasound imaging, and ultrasound treatment; Medical ultrasound imaging and ultrasound treatment services; Beauty care services; Medspa services for health and beauty of the body and health spa services for health and beauty of the body; cosmetic skin care services; Providing medical aesthetic procedures, namely treating the skin for wrinkles, fine lines and skin lifting; Cosmetic body care services; Providing medical aesthetic services, namely providing noninvasive ultrasound procedures in the nature of medical ultrasound imaging and ultrasound treatment services

Abstract

Embodiments provide an ultrasound treatment system. In some embodiments, the system includes a removable transducer module having an ultrasound transducer. In some embodiments, the system can include a hand wand and a control module that is coupled to the hand wand and has a graphical user interface for controlling the removable transducer module, and an interface coupling the hand wand to the control module. The interface may provide power to the hand wand or may transfer a signal from the hand wand to the control module. In some embodiments, the treatment system may be used in cosmetic procedures on at least a portion of a face, head, neck, and/or other part of a patient.

IPC Classes  ?

• A61B 8/08 - Detecting organic movements or changes, e.g. tumours, cysts, swellings
• A45D 19/00 - Devices for washing the hair or the scalp; Similar devices for colouring the hair
• A45D 44/00 - Other cosmetic or toiletry articles, e.g. for hairdressers' rooms
• A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
• A61N 7/00 - Ultrasound therapy
• G10K 11/35 - Sound-focusing or directing, e.g. scanning using mechanical steering of transducers

Abstract

The present invention relates the use of botulinum toxin for the treatment of facial wrinkles, wherein botulinum toxin is administered at high doses (e.g., 50 U to 200 U) using small injection volumes (e.g., 0.05 ml to 0.35 ml). Furthermore, the present invention relates to a method for the treatment of facial wrinkles (e.g., glabellar frown lines) by injecting small volumes of a highly concentrated botulinum toxin solution into a target facial area of a subject.

IPC Classes  ?

• A61K 8/66 - Enzymes
• A61Q 19/08 - Anti-ageing preparations

Abstract

The present invention relates to a plunger (20) and a finger grip (30) for a syringe assembly (100), methods for manufacturing them, to a syringe assembly (100), to a kit comprising parts of a syringe assembly (100), and to the use of a syringe assembly (100) or of a kit, wherein the syringe assembly (100) comprises a syringe barrel (10), a finger grip (30) having flanges (31, 32), and a plunger (20) having a plunger rod (21) and a plunger head (22). The plunger (20) comprises a grip pad (23) made by injection molding and attached to a proximal facing surface (24) of the plunger head. The finger grip (20) comprises a grip pad (35) also made by injection molding and attached to a distal facing surface of at least one flange (31, 32) of the finger grip (30).

IPC Classes  ?

• A61M 5/31 - Syringes - Details

Abstract

A liquid composition for improving the facial contour and shape of the human or animal face by injection, the liquid composition comprising water and at least one of the following components A, B and C: A liquid composition for improving the facial contour and shape of the human or animal face by injection, the liquid composition comprising water and at least one of the following components A, B and C: at least one component A, which leads to an osmotic concentration in the range from 500 to 5000 mOsm in the liquid composition, A liquid composition for improving the facial contour and shape of the human or animal face by injection, the liquid composition comprising water and at least one of the following components A, B and C: at least one component A, which leads to an osmotic concentration in the range from 500 to 5000 mOsm in the liquid composition, at least one high viscosity component B, which leads to a viscosity of the liquid composition in the range from 10 to 1500 mPas, A liquid composition for improving the facial contour and shape of the human or animal face by injection, the liquid composition comprising water and at least one of the following components A, B and C: at least one component A, which leads to an osmotic concentration in the range from 500 to 5000 mOsm in the liquid composition, at least one high viscosity component B, which leads to a viscosity of the liquid composition in the range from 10 to 1500 mPas, at least one micro-particles component C, comprising micro-particles with an average particle size not larger than 0.25 mm, preferably in the range of 0.001 mm to 0.25 mm, and optionally comprising A liquid composition for improving the facial contour and shape of the human or animal face by injection, the liquid composition comprising water and at least one of the following components A, B and C: at least one component A, which leads to an osmotic concentration in the range from 500 to 5000 mOsm in the liquid composition, at least one high viscosity component B, which leads to a viscosity of the liquid composition in the range from 10 to 1500 mPas, at least one micro-particles component C, comprising micro-particles with an average particle size not larger than 0.25 mm, preferably in the range of 0.001 mm to 0.25 mm, and optionally comprising a local anesthetic compound D.

IPC Classes  ?

• A61K 8/73 - Polysaccharides
• A61K 8/24 - Phosphorus; Compounds thereof
• A61K 8/42 - Amides
• A61K 8/60 - Sugars; Derivatives thereof
• A61Q 19/08 - Anti-ageing preparations
• A61K 8/96 - Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof, of undetermined constitution
• A61K 8/85 - Polyesters
• A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients

Abstract

This invention relates to improved uses of botulinum neurotoxins in the treatment of sialorrhea or diseases or conditions relating to increased saliva production. In particular are botulinum neurotoxins disclosed which are administered into parotid and submandibular glands in a dose ratio between 1.45 to 1 and 1.7 to 1.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61P 1/00 - Drugs for disorders of the alimentary tract or the digestive system
• A61P 43/00 - Drugs for specific purposes, not provided for in groups

Abstract

The present invention generally relates to the use of botulinum toxin for the reduction of skin pore size and/or sebum production using specific dosing regimens and injection schemes. Specifically, the botulinum toxin is administered by intradermal injection into the skin of a subject at a concentration of 11 U/ml to 19 U/ml and at a volume of 0.07 ml to 0.12 ml per injection point. Furthermore, the present invention relates to a method for the reduction of skin pore size and/or sebum production using said specific dosing regimens and injection schemes.

IPC Classes  ?

• A61K 8/66 - Enzymes
• A61Q 19/00 - Preparations for care of the skin
• A61Q 19/08 - Anti-ageing preparations

Abstract

The present invention relates to a liquid formulation comprising (i) botulinum toxin, (ii) human serum albumin (HSA), and optionally (iii) a tonicity agent and/or (iv) a buffering agent. In one aspect, the liquid formulation is characterized by a very low iron ion concentration. In another aspect, liquid formulation is characterized by the absence or very low concentration of tryptophan and/or N-acetyl-tryptophan. According to the present invention, the liquid formulation can be prepared by a method comprising the steps of contacting human serum albumin with a chelating agent to obtain a mixture and removing the chelating agent from the mixture. Furthermore, the present invention relates to the use of the liquid formulation in the treatment of therapeutic indications and cosmetic conditions.

IPC Classes  ?

• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 8/00 - Cosmetics or similar toiletry preparations
• A61K 47/42 - Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
• A61Q 19/10 - Washing or bathing preparations
• A61P 13/06 - Anti-spasmodics

Abstract

The present invention relates to a liquid botulinum toxin formulation comprising: (i) botulinum toxin, (ii) a stabilizing protein such as human serum albumin, (iii) a chelating agent (e.g., EDTA) or phosphate, and optionally (iv) a salt of calcium, magnesium or zinc, (v) a tonicity agent and/or (vi) a buffering agent. In addition, the present invention relates to the use of the liquid botulinum toxin formulation for therapeutic and cosmetic treatments.

IPC Classes  ?

• A61K 8/00 - Cosmetics or similar toiletry preparations
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/02 - Inorganic compounds
• A61K 47/18 - Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
• A61K 47/42 - Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)

Goods & Services

Medical devices for nonsurgical cosmetic treatments; Medical ultrasound apparatus; Cosmetic apparatus using ultrasound for performing aesthetic skin treatment procedures; Medical apparatus for use in treating dermatological disorders; Medical instruments for use in treating tissue below a skin surface Printed educational materials in the field of aesthetics and dermatology; Printed publications, namely, brochures, training materials, and hand-outs in the field of healthcare; Printed training materials in the field of aesthetics and dermatology Beauty spa services, namely, cosmetic body care; Cosmetic skin care services; Dermatology services; Medical services; Providing a web site featuring medical information; Providing a website featuring information in the field of aesthetics and dermatological health

Goods & Services

Medical devices for nonsurgical cosmetic treatments; Medical ultrasound apparatus; Cosmetic apparatus using ultrasound for performing aesthetic skin treatment procedures; Medical apparatus for use in treating dermatological disorders; Medical instruments for use in treating tissue below a skin surface Printed educational materials in the field of aesthetics and dermatology; Printed publications, namely, brochures, training materials, and hand-outs in the field of healthcare; Printed training materials in the field of aesthetics and dermatology Beauty spa services, namely, cosmetic body care; Cosmetic skin care services; Dermatology services; Medical services; Providing a web site featuring medical information; Providing a website featuring information in the field of aesthetics and dermatological health

Goods & Services

On-line advertisements; provision of space on web-sites for advertising goods and services; on-line advertising on a computer network. Providing electronic publications; electronic text publishing services; creation [writing] of educational content for podcasts; electronic publication of texts and printed matter, other than publicity texts, on the internet; education services relating to pharmacy; medical education services; training services for medical visitors; providing online electronic publications, not downloadable, conducting of instructional seminars; providing continuing medical education courses; on-line publishing services; arranging and conducting of conferences; arranging and conducting of congresses; arrangement of conventions for educational purposes; organisation of seminars; arranging and conducting of colloquiums; arranging and conducting of workshops; arranging, conducting and organisation of seminars; arranging of lectures; creation [writing] of podcasts.

Goods & Services

(1) Ultrasound imaging and therapy apparatus.

Goods & Services

Administration of a customer loyalty program which provides discounts on dermatological and aesthetics goods or services; Arranging and conducting incentive reward programs to promote the sale of dermatological and aesthetics good or services

Goods & Services

Aesthetician services; medical skin care services; medical ultrasound imaging services; dermatology services; providing medical information in the field of dermatology; providing medical advice in the field of dermatology; medical services in the field of energy treatment of skin; medical services, namely, dermatology treatment; providing medical information in the field of medical skin care services; providing medical advice in the field of medical ultrasound imaging services; providing information about health and wellness, namely, aesthetics and dermatology via a website; health spa services, namely, body care services; beauty spa services, namely, body care.

Goods & Services

Online advertising; advertising; provision of an on-line marketplace for buyers and sellers of goods and services; on-line advertising on a computer network. Training in the area of pharmacy; training in the medical field; vocational training and further education; vocational training services; vocational training services for medical personnel; vocational training services in the area of cosmetics; provision of online publications; carrying out further education seminars; providing electronic publications [non-downloadable]; publication of printed matter; publication of printed matter in the medical field; providing non-downloadable online electronic publications; providing on-line publications [non-downloadable]; organization of conferences for educational purposes; publication of electronic publications, printed matter and printed publications and providing non-downloadable online publications; arranging, conducting and organization of workshops; arranging, conducting and organization of colloquiums; organization of congresses; organization of seminars; education services, namely, conducting of presentations; arranging, conducting and organization of seminars; publication and provision of books; publication, rental and leasing of printed matter; publication and provision of non-downloadable online publications and electronic publications; publication of magazines and providing on-line non-downloadable magazines.

Goods & Services

Pharmaceuticals; medical products; Medicines for human purposes; Pre-filled syringes for medical and pharmaceutical purposes; Pharmaceutical and medical preparations for dermatological purposes and Pharmaceutical skin care preparation and Medicated preparations for nourishing the skin; Injectable pharmaceuticals; Dermatological preparations, Pharmaceutical preparations and Medical preparations, for use in the following fields: Skin rejuvenation. publishing and issuing of scientific papers; Conducting of seminars and congresses, Congresses, Arranging of lecture colloquiums and Arranging of workshops; Training of doctors; all the aforesaid services featuring the following fields: Esthetics, beauty and medicine. Skin treatment services; Consultancy and information in relation to the following fields: Pharmaceutical and medical products; Consultancy and information, in relation to the following fields: Medical equipment and Medical instruments; Counselling services in relation to the following fields: Esthetics, Beauty and Medicine.

Goods & Services

Paper, cardboard; printed matter, namely, scientific publications, periodical publications, and circulars, pamphlets, handbooks, curriculum, information cards, and photographs, namely, handbooks, exercise books, notebooks, reference books, books; paper; writing stationery; all the aforesaid goods in the field of aesthetics, beauty and medicine. Advertising; promotion services; all the aforesaid services in the fields of aesthetics, beauty and medicine. Publication and editing of scientific papers; conducting of seminars, congresses, arranging of congresses, lecture colloquiums and workshops; training courses for doctors; all the aforesaid services in the fields of aesthetics, beauty and medicine. Skin treatment services; consultancy and information services relating to pharmaceutical and medical products; consultancy and information services relating to medical devices and instruments; consultations in the field of aesthetics, beauty and medicine.

Goods & Services

(1) Online advertising; advertising; provision of an on-line marketplace for buyers and sellers of goods and services; on-line advertising on a computer network. (2) Training in the area of pharmacy; training in the medical field; vocational training and further education; vocational training services; vocational training services for medical personnel; vocational training services in the area of cosmetics; provision of online publications; carrying out further education seminars; providing electronic publications [non-downloadable]; publication of printed matter; publication of printed matter in the medical field; providing non-downloadable online electronic publications; providing on-line publications [non-downloadable]; organization of conferences for educational purposes; publication of electronic publications, printed matter and printed publications and providing non-downloadable online publications; arranging, conducting and organization of workshops; arranging, conducting and organization of colloquiums; organization of congresses; organization of seminars; education services, namely, conducting of presentations; arranging, conducting and organization of seminars; publication and provision of books; publication, rental and leasing of printed matter; publication and provision of non-downloadable online publications and electronic publications; publication of magazines and providing on-line non-downloadable magazines.

Goods & Services

online advertising services; advertising services; provision of an on-line marketplace for buyers and sellers of goods and services; on-line advertising on a computer network training in the area of pharmacy; training in the medical field; vocational training and further vocational education in the field of aesthetics, beauty, and medicine; vocational training services in the field of aesthetics, beauty, and medicine; vocational training services for medical personnel in the field of aesthetics, beauty, and medicine; vocational training services in the area of cosmetics; provision of online non-downloadable publications in the nature of books, journals, scientific articles, magazines, brochures, pamphlets in the field of aesthetics, beauty and medicine; carrying out further continuing professional education seminars in the field of aesthetics, beauty, and medicine; providing electronic publications, non-downloadable, in the nature of books, journals, scientific articles, magazines, brochures, pamphlets in the field of aesthetics, beauty, and medicine; publication of printed matter; publication of printed matter in the medical field; providing non-downloadable online electronic publications in the nature of books, journals, scientific articles, magazines, brochures, pamphlets in the field of aesthetics, beauty, and medicine; providing on-line publications, non-downloadable, in the nature of books, journals, scientific articles, magazines, brochures, pamphlets in the field of aesthetics, beauty, and medicine; organization and conducting of conferences for educational purposes in the field of aesthetics, beauty, and medicine; publication of electronic publications, printed matter and printed publications and providing non-downloadable online publications in the nature of books, journals, scientific articles, magazines, brochures, pamphlets in the field of aesthetics, beauty, and medicine; arranging, conducting and organization of workshops in the field of aesthetics, beauty, and medicine; arranging, conducting and organization of colloquiums in the field of aesthetics, beauty, and medicine; organization of congresses in the field of aesthetics, beauty, and medicine; organization and conducting of seminars in the field of aesthetics, beauty, and medicine; education services, namely, conducting of presentations in the field of aesthetics, beauty, and medicine; arranging, conducting and organization of seminars in the field of aesthetics, beauty, and medicine; publication of books and provision of online non-downloadable e-books in the field of aesthetics, beauty, and medicine; publication, rental and leasing of printed matter in the nature of books; publication of printed matter and provision of non-downloadable online publications and electronic publications in the nature of books, journals, scientific articles, magazines, brochures, pamphlets in the field of aesthetics, beauty, and medicine; publication of magazines and providing on-line non-downloadable magazines in the field of aesthetics, beauty, and medicine

Goods & Services

Pharmaceutical preparations; pharmaceutical products for use in the aesthetic field and the treatment of diseases; medical preparations; medical products; medicine for human purposes; pharmaceuticals; pre-filied syringes for medical purposes (pharmaceuticals); nervines. Medical instruments and devices; hypodermic needles; medical syringes; systems for injecting medical or pharmaceutical fluids; one-dose injectable devices of medical or pharmaceutical fluids; receptacles for applying medicine.

Goods & Services

On-line advertisements by means of online advertising services; provision of space on web-sites for advertising goods and services; on-line advertising on a computer network Providing online non-downloadable electronic publications in the nature of brochures in the field of medicine and healthcare; electronic text publishing services, namely, publication of text and graphic works of others on the internet featuring information on medicine and healthcare; creation, namely scriptwriting of educational content for podcasts for non-advertising purposes; electronic publication of texts and printed matter, other than publicity texts, on the internet, namely, publication of text and graphic works of others on the internet featuring information on medicine and healthcare; education services, namely, providing continuing professional education courses relating to pharmacy; providing medical education services in the nature of continuing medical education courses; training services for medical visitors in the field of medicine and healthcare; providing online electronic publications, in the nature of articles in the field of medicine and healthcare, not downloadable, conducting of instructional seminars in the field of medicine and healthcare; providing continuing medical education courses; on-line electronic publishing services of books and periodicals; arranging and conducting of conferences in the field of medicine and healthcare; arranging and conducting of congresses in the field of medicine and healthcare; arrangement and conducting of conventions for educational purposes in the field of medicine and healthcare; organization of seminars in the field of medicine and healthcare; arranging and conducting of colloquiums in the field of medicine and healthcare; arranging and conducting of workshops in the field of medicine and healthcare; arranging, conducting and organization of seminars in the field of medicine and healthcare; arranging and conducting of lectures in the field of medicine and healthcare; creation, namely, scriptwriting of podcasts for non-advertising purposes

Abstract

Embodiments of a dermatological cosmetic treatment and imaging system and method can include use of transducer to simultaneously or substantially simultaneously produce multiple cosmetic treatment zones in tissue. The system can include a hand wand, a removable transducer module, a control module, and/or graphical user interface. In some embodiments, the cosmetic treatment system may be used in cosmetic procedures, including brow lifts, fat reduction, sweat reduction, and treatment of the décolletage. Skin tightening, lifting and amelioration of wrinkles and stretch marks are provided.

IPC Classes  ?

• A61N 7/00 - Ultrasound therapy
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61N 7/02 - Localised ultrasound hyperthermia
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

Goods & Services

(1) Paper, cardboard; printed matter, namely, scientific publications, periodical publications, and circulars, pamphlets, handbooks, curriculum, information cards, and photographs, namely, handbooks, exercise books, notebooks, reference books, books; paper; writing stationery; all the aforesaid goods in the field of aesthetics, beauty and medicine. (1) Advertising; promotion services; all the aforesaid services in the fields of aesthetics, beauty and medicine. (2) Publication and editing of scientific papers; conducting of seminars, congresses, arranging of congresses, lecture colloquiums and workshops; training courses for doctors; all the aforesaid services in the fields of aesthetics, beauty and medicine. (3) Skin treatment services; consultancy and information services relating to pharmaceutical and medical products; consultancy and information services relating to medical devices and instruments; consultations in the field of aesthetics, beauty and medicine.

Goods & Services

paper, cardboard; printed matter, namely, scientific publications in the nature of books, journals, scientific articles, magazines, brochures, pamphlets, periodical publications in the field of aesthetics, beauty and medicine, and circulars charts, pamphlets, handbooks, curriculum, information cards, and photographs, namely, handbooks, exercise books, notebooks, reference books, books, all in the field of aesthetics, beauty and medicine; paper; writing stationery paper and envelopes; all the aforesaid goods in the field of aesthetics, beauty and medicine advertising services; sales promotion services; all the aforesaid services in the fields of aesthetics, beauty, and medicine publication and editing of scientific newspapers; conducting of seminars and congresses, and arranging of congresses, lecture colloquiums and workshops in the field of aesthetics, beauty, and medicine; training courses for doctors in the field of in the field of aesthetics, beauty, and medicine; all the aforesaid services in the fields of aesthetics, beauty and medicine cosmetic skin care treatment services; medical consultancy and information services relating to pharmaceutical and medical products; medical consultancy and information services relating to medical devices and instruments; consultations in the field of medical aesthetics, beauty and medicine

Abstract

The present invention relates to the synergistic effect of calcium hydroxyapatite particles and hyaluronic acid on the bio-stimulation. The invention refers to an injectable composition comprising one or more types of calcium hydroxyapatite particles and hyaluronic acid and to a method for preparing such injectable composition. Furthermore, it relates to a cosmetic method for improving appearance of the skin and/or contour of a subject by means of the injectable composition. Moreover, the invention refers to the injectable composition for use in a method of treating a pathologic condition associated with pathologic deterioration of connective tissue.

IPC Classes  ?

• A61K 8/24 - Phosphorus; Compounds thereof
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 33/42 - Phosphorus; Compounds thereof
• A61K 31/728 - Hyaluronic acid
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61Q 19/00 - Preparations for care of the skin
• A61K 8/73 - Polysaccharides
• A61Q 19/08 - Anti-ageing preparations

Abstract

The present invention provides methods for treating OFF episodes in a Parkinson's Disease patient comprising administering levodopa to the pulmonary system of a patient wherein after administration, the patient's Unified Parkinson's Disease Rating Scale (UPDRS) Part 3 score is improved by, for example, at least about 5 points as compared to placebo control and/or as compared to the patient's UDPRS Part 3 score prior to administration. The invention also provides methods of reducing mean daily OFF time in a Parkinson's patient.

IPC Classes  ?

• A61K 31/198 - Alpha-amino acids, e.g. alanine, edetic acid (EDTA)
• A61K 9/00 - Medicinal preparations characterised by special physical form

Goods & Services

Pharmaceutical products for use in dermatology in the aesthetic field; pharmaceutical products for relaxing muscles; pharmaceutical products for the treatment of wrinkles and facial fines and for the treatment of cerebral and neurological disorders, diseases and conditions; medical products for use in dermatology in the aesthetic field, namely, medicated dermatological preparations and substances; medical products for relaxing muscles, namely, muscle relaxants; medical products in the nature of botulinum toxin for the treatment of wrinkles and facial lines and the treatment of cerebral and neurological disorders, disease and conditions; medicaments for human medical use for the treatment of cerebral and neurological disorders, diseases and conditions; prefilled syringes sold filled with botulinum toxin for medical and pharmaceutical use in dermatology in the aesthetic field, for relaxing muscles, for the treatment of wrinkles and facial lines and for the treatment of cerebral and neurological disorders, diseases and conditions Medical apparatus and instruments for medical use in dermatological procedures; hypodermic needles; hypodermic needles for injections; syringes for medical purposes; systems for injections consisting of hypodermic needles for injections; syringes for medical purposes and injection devices for pharmaceuticals in the nature of botulinum toxin; injection equipment for single doses, namely, needles for injections; containers for the administration of medicines, namely, containers for botulinum toxin

Goods & Services

(1) Pharmaceutical preparations; pharmaceutical products for use in the aesthetic field and the treatment of diseases; medical preparations; medical products; medicine for human purposes; pharmaceuticals; pre-filied syringes for medical purposes (pharmaceuticals); nervines. (2) Medical instruments and devices; hypodermic needles; medical syringes; systems for injecting medical or pharmaceutical fluids; one-dose injectable devices of medical or pharmaceutical fluids; receptacles for applying medicine.

Goods & Services

Books; printed matter; printed instructional and teaching material; instructional and teaching material (except apparatus); paper and stationery; printed publications; periodical publications; magazines [periodicals]; newspapers. Online advertising; advertising; provision of an on-line marketplace for buyers and sellers of goods and services; on-line advertising on a computer network. Training in the area of pharmacy; training in the medical field; vocational training and further education; vocational training services; vocational training services for medical personnel; vocational training services in the area of cosmetics; provision of online publications; carrying out further education seminars; providing electronic publications [non-downloadable]; publication of printed matter; publication of printed matter in the medical field; providing non-downloadable online electronic publications; providing on-line publications [non-downloadable]; organization of conferences for educational purposes; publication of electronic publications, printed matter and printed publications and providing non-downloadable online publications; arranging, conducting and organization of workshops; arranging, conducting and organization of colloquiums; organization of congresses; organization of seminars; education services, namely, conducting of presentations; arranging, conducting and organization of seminars; publication and provision of books; publication, rental and leasing of printed matter; publication and provision of non-downloadable online publications and electronic publications; publication of magazines and providing on-line non-downloadable magazines. Research in the medical field; research and development services; medical research; medical and pharmaceutical research services; pharmaceutical research and development; scientific research and development; scientific and technological services.

Abstract

The present invention relates to a syringe barrel having an interior surface coated with a silicone film having a thickness in the range of 5 nm to 100 nm. It further relates to a method for manufacturing said syringe barrel comprising the step of reducing an initial thickness of a pre-formed silicone film on the interior surface of a syringe barrel to a thickness within the range of about 5 nm to about 100 nm by exposing the syringe barrel to an organic solvent or by subjecting the syringe barrel to mechanical treatment. Furthermore, the present invention relates to a syringe comprising the syringe barrel of the invention, a kit comprising said syringe, and cosmetic and therapeutic uses of said syringe.

IPC Classes  ?

• A61M 5/31 - Syringes - Details
• B05C 9/14 - Apparatus or plant for applying liquid or other fluent material to surfaces by means not covered by groups , or in which the means of applying the liquid or other fluent material is not important for applying liquid or other fluent material and performing an auxiliary operation the auxiliary operation involving heating
• B05D 5/08 - Processes for applying liquids or other fluent materials to surfaces to obtain special surface effects, finishes or structures to obtain an anti-friction or anti-adhesive surface
• C03C 17/30 - Surface treatment of glass, e.g. of devitrified glass, not in the form of fibres or filaments, by coating with organic material with silicon-containing compounds
• B05D 3/12 - Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by mechanical means

Abstract

222-O- repetitive units of 8 to 90. Furthermore, the present invention relates to a method for preparing said dermal filler composition and its use for cosmetic purposes.

IPC Classes  ?

• A61L 27/20 - Polysaccharides
• A61L 27/52 - Hydrogels or hydrocolloids
• A61K 8/73 - Polysaccharides
• A61Q 19/08 - Anti-ageing preparations

Abstract

A process for producing a composition comprising a crosslinked hydrogel is proposed. The process comprises providing a container body (2), wherein the container body (2) has a body inner wall (21) and a body outer wall (22), wherein the body inner (21) wall is configured to be tempered, filling of a fluid (7) comprising at least a mixture of a polymer and water into the container body (2), and agitating the fluid. For crosslinking of the fluid (7), a container insert (3) is provided, the container insert (3) having an insert outer wall (32) which is configured to be tempered and a container assembly (1) is formed by inserting the container insert (3) into the container body (2) so that the insert outer wall (32) of the container insert (3) and the body inner wall (21) of the container body (2) are separated by a gap (9) of constant width and define a volume (6) for receiving the fluid (7). Crosslinking of the fluid (7) is then performed while tempering the insert outer wall (32) and the body inner wall (21) to form a crosslinked hydrogel.

IPC Classes  ?

• C08J 3/075 - Macromolecular gels
• C08J 3/24 - Crosslinking, e.g. vulcanising, of macromolecules
• C08B 37/08 - Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
• A61L 27/52 - Hydrogels or hydrocolloids
• A61K 8/73 - Polysaccharides
• A61Q 19/08 - Anti-ageing preparations
• A61L 27/20 - Polysaccharides

Abstract

The invention proposes a method for preparing a cross-linked material, comprising forming amide bonds that conjugate one or more fibroin moieties with one or more polysaccharide moieties. The invention further relates to a cross-linked material obtainable from such method and to an injectable composition comprising the obtained cross-linked material. The cross-linked material can be a hydrogel and/or a super-volumizer and can be used in cosmetic and pharmaceutical applications.

IPC Classes  ?

• A61L 27/20 - Polysaccharides
• A61L 27/22 - Polypeptides or derivatives thereof
• A61L 27/52 - Hydrogels or hydrocolloids

Abstract

The invention proposes a method for preparing a cross-linked material, comprising forming amide bonds that conjugate one or more fibroin moieties with one or more polysaccharide moieties. The invention further relates to a cross-linked material obtainable from such method and to an injectable composition comprising the obtained cross-linked material. The cross-linked material can be a hydrogel and/or a super-volumizer and can be used in cosmetic and pharmaceutical applications.

IPC Classes  ?

• A61L 27/20 - Polysaccharides
• A61L 27/22 - Polypeptides or derivatives thereof
• A61L 27/52 - Hydrogels or hydrocolloids

Goods & Services

Pharmaceutical preparations for human purposes.

Goods & Services

Aesthetician services; Medical skin care services; Medical ultrasound imaging services; Dermatology services; Providing medical information in the field of dermatology; Providing medical advice in the field of dermatology; Medical services in the field of energy treatment of skin; Medical services, namely, dermatology treatment; Providing medical information in the field of medical skin care services; Providing medical advice in the field of medical ultrasound imaging services; Providing a website featuring information about health and wellness, namely, aesthetics and dermatology; Health spa services, namely, cosmetic body care services; Beauty spa services, namely, cosmetic body care

Goods & Services

Cosmetic and plastic surgery, namely, cosmetic treatment with acoustic or ultrasound energy for the depiction of tissue and creation of thermal damage and the healing of such tissue; non-invasive cosmetic medical procedures, namely, cosmetic treatment with acoustic or ultrasound energy for the depiction of tissue and creation of thermal damage and the healing of such tissue; cosmetic and plastic surgery; dermatology services; medical services, namely, depiction of tissue and creation of thermal damage and the healing of such tissue..

Abstract

The present invention relates to methods for reducing facial lines or wrinkles of the skin or of removing facial asymmetries by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition may be devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 9/00 - Medicinal preparations characterised by special physical form

Abstract

The present invention relates to methods for treating diseases and disorders by administering a composition containing the neurotoxic component of a Clostridium botulinum toxin complex, wherein the composition may be devoid of any other protein of the Clostridium botulinum toxin complex and wherein the composition is administered at short intervals and/or in high doses.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 9/00 - Medicinal preparations characterised by special physical form

Abstract

The present invention provides improved pharmaceutical formulations for pulmonary delivery having improved chemical and physical stability of the therapeutic, prophylactic or diagnostic agent as compared to formulations known in the art. The improved pharmaceutical formulations of the invention for administration to the respiratory system of a patient for the treatment of a variety of disease conditions comprise a mass of biocompatible particles comprising an active agent, and a hydrogenated starch hydrosylate (HSH). The improvement over the prior art comprises the presence of HSH in the pharmaceutical formulation. The invention further relates to a method of treating diseases comprising administering the pharmaceutical formulations of the present invention to the respiratory system of a patient in need of treatment.

IPC Classes  ?

• A61K 31/58 - Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 9/16 - Agglomerates; Granulates; Microbeadlets
• A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
• A61K 31/13 - Amines, e.g. amantadine
• A61K 47/36 - Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
• A61K 38/29 - Parathyroid hormone (parathormone); Parathyroid hormone-related peptides

Abstract

The present invention relates a botulinum toxin prefilled syringe system with desirable injection force characteristics, in particular low gliding force and low break loose force, comprising a syringe barrel of glass containing a liquid botulinum toxin composition, a plunger stopper and a closure device such as a tip cap or a needle shield. In addition, the present invention relates to a kit comprising the botulinum toxin prefilled syringe system, and optionally instructions for use, and to the use of the botulinum toxin prefilled syringe system in therapeutic and cosmetic applications.

IPC Classes  ?

• A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
• A61M 5/48 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests having means for varying, regulating, indicating or limiting injection pressure
• A61M 5/178 - Syringes
• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)

Abstract

Embodiments of a dermatological cosmetic treatment and/or imaging system and method adapted to alter placement and position of multiple (e.g., two or more) cosmetic treatment zones in tissue from ultrasound beams from a transducer, simultaneous multi-focus therapy at multiple depths, and/or dithering ultrasound beams from a transducer to alter placement and position of multiple cosmetic treatment zones in tissue. The system can include a hand wand, a removable transducer module, and a control module. In some embodiments, the cosmetic treatment system may be used in various cosmetic procedures.

IPC Classes  ?

• A61N 7/02 - Localised ultrasound hyperthermia
• A61B 8/08 - Detecting organic movements or changes, e.g. tumours, cysts, swellings
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves

Abstract

A method for treating undesired implanted calcium phosphate tissue filler by administering an effective amount of a pharmaceutically acceptable hyperosmotic composition. The hyperosmotic composition may be hyperosmotic solution, particularly a hyperosmotic aqueous solution. The hyperosmotic composition is administration to an area containing the undesired calcium phosphate tissue filler. Administration of the hyperosmotic composition can reduce, dilute/or redistribute an undesired amount or accumulation of implanted calcium phosphate tissue filler implanted. Methods herein can ameliorate undesired filler that is implanted in an undesired or unintended location, that migrates to an undesired location, that results in an undesired visual result, and/or that results in undesired compression of surrounding tissue, and/or that results in pain, infection, and/or inflammation.

IPC Classes  ?

• A61K 33/00 - Medicinal preparations containing inorganic active ingredients
• A61K 8/19 - Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
• A61K 8/60 - Sugars; Derivatives thereof
• A61Q 19/08 - Anti-ageing preparations
• A61P 17/00 - Drugs for dermatological disorders
• A61L 27/12 - Phosphorus-containing materials, e.g. apatite

Goods & Services

Cosmetic and plastic surgery, namely, cosmetic treatment with energy for the depiction of tissue and creation of thermal damage and the healing of such tissue; non-invasive cosmetic medical procedures, namely, cosmetic treatment with energy for the depiction of tissue and creation of thermal damage and the healing of such tissue; cosmetic and plastic surgery, namely, creation of thermal damage and the healing of such tissue; dermatology services, namely, depiction of tissue; medical services in the field of dermatology; cosmetic skin care services; providing a web site featuring cosmetic and dermatology information; providing cosmetic, skin care and dermatological information.

Goods & Services

Downloadable mobile applications for administering reward and customer loyalty program accounts Printed educational materials in the field of dermatology, medical aesthetics, and neurology; Printed materials, namely, written articles in the field of dermatology, medical aesthetics, and neurology; Printed training materials in the field of dermatology, medical aesthetics, and neurology Advertising, marketing and promotion services in the field of dermatological, medical aesthetic, and neurological products; Arranging and conducting incentive reward programs to promote the sale of dermatological, medical aesthetic, and neurological products; Business administration of patient reimbursement programs; Marketing services in the nature of promotion of third-party goods and services by brand ambassadors; Providing consumer information in the field of dermatology, medical aesthetics and neurology On-line video journals, namely, vlogs featuring nondownloadable videos in the field of dermatology, medical aesthetics and neurology; Providing a website featuring blogs and non-downloadable publications in the nature of articles and brochures in the field(s) of dermatology, medical aesthetics and neurology; Providing a website featuring non-downloadable photographs in the field of dermatology, medical aesthetics and neurology Providing a website featuring information in the field of medical aesthetics, neurological, and dermatological health; Providing health information; Providing health information in the field of dermatology, medical aesthetics and neurology

Abstract

This invention relates to novel uses of botulinum neurotoxin in treating a tremor, in particular to a botulinum neurotoxin for use in treating a tremor of the upper limb comprising the administration of a botulinum neurotoxin to at least one muscle of the forearm/wrist, elbow and shoulder, wherein the botulinum neurotoxin is administered to at least one muscle of the forearm/wrist selected from the group of M. extensor carpi ulnaris (ECU), M. extensor carpi radialis (ECR), M. pronator quadratus (PQ) and M. supinator in a dosage in the range of 2 to 6 U and wherein the botulinum neurotoxin is administered to at least one muscle of the elbow in a dosage of about 20 U and to at least one muscle of the shoulder in a dosage of about 15 U.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61P 25/14 - Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia

Abstract

Embodiments of a dermatological cosmetic treatment and/or imaging system and method adapted for dithering ultrasound beams from a transducer to alter placement and position of one or multiple cosmetic treatment zones in tissue, simultaneous multi-focus therapy using multi-channel signal mixing, and/or dithering ultrasound beams from a transducer to alter placement and position of one or multiple cosmetic treatment zones in tissue, configured for using imaging for improved ultrasound therapy efficacy, and/or adapted for imaging with multiple focal zone sequencing and triggering for mechanically translated and/or steered ultrasound transducers are provided herein. The system can include a hand wand, a removable transducer module, and a control module. In some embodiments, the cosmetic treatment system may be used in various cosmetic procedures.

IPC Classes  ?

• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61N 7/02 - Localised ultrasound hyperthermia

Goods & Services

Cosmetic restoration and augmentation preparations, namely, biocompatible injections consisting of dermal fillers for use as treatment alternatives to plastic surgery and internal augmentation, all the aforesaid for medical use; filled syringes for medical purposes. Medical devices, apparatus and instruments used for cosmetic purposes for restoration and augmentation, namely injection devices.

Abstract

The present invention relates to a prefilled plastic container, such as a plastic syringe, comprising an aqueous botulinum toxin formulation. The aqueous botulinum toxin formulation in the prefilled plastic container is stable for a prolonged time period. Furthermore, the present invention relates to a kit comprising the prefilled plastic container, and to the use of the prefilled plastic container for therapeutic and cosmetic purposes.

IPC Classes  ?

• A61M 5/31 - Syringes - Details
• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61Q 19/08 - Anti-ageing preparations
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 8/64 - Proteins; Peptides; Derivatives or degradation products thereof
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61M 5/315 - Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod; Appliances on the rod for facilitating dosing
• A61K 8/66 - Enzymes
• A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
• A61M 5/32 - Syringes - Details - Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles

Abstract

The present invention relates to a plunger (20) and a finger grip (30) for a syringe assembly (100), methods for manufacturing them, to a syringe assembly (100), to a kit comprising parts of a syringe assembly (100), and to the use of a syringe assembly (100) or of a kit, wherein the syringe assembly (100) comprises a syringe barrel (10), a finger grip (30) having flanges (31, 32), and a plunger (20) having a plunger rod (21) and a plunger head (22). The plunger (20) comprises a grip pad (23) made by injection molding and attached to a proximal facing surface (24) of the plunger head. The finger grip (20) comprises a grip pad (35) also made by injection molding and attached to a distal facing surface of at least one flange (31, 32) of the finger grip (30).

IPC Classes  ?

• A61M 5/31 - Syringes - Details

Abstract

The present invention relates to a plunger (20) and a finger grip (30) for a syringe assembly (100), methods for manufacturing them, to a syringe assembly (100), to a kit comprising parts of a syringe assembly (100), and to the use of a syringe assembly (100) or of a kit, wherein the syringe assembly (100) comprises a syringe barrel (10), a finger grip (30) having flanges (31, 32), and a plunger (20) having a plunger rod (21) and a plunger head (22). The plunger (20) comprises a grip pad (23) made by injection molding and attached to a proximal facing surface (24) of the plunger head. The finger grip (20) comprises a grip pad (35) also made by injection molding and attached to a distal facing surface of at least one flange (31, 32) of the finger grip (30).

IPC Classes  ?

• A61M 5/31 - Syringes - Details

Abstract

The present invention relates to a modified hyaluronic acid derivative, wherein the —CH2—OH group of at least one N-acetyl-D-glucosamine unit is modified into an aldehyde group having the structure —CH2—O—CH2—CHO, methods for preparing same and applications thereof.

IPC Classes  ?

• A61K 8/73 - Polysaccharides
• A61K 8/04 - Dispersions; Emulsions
• A61Q 19/08 - Anti-ageing preparations

Abstract

Embodiments are provided that enhance ultrasound efficacy by for example, high efficiency, signal measurement, calibration, and assurance systems with a control system radio-frequency (RE) driver configured to drive one or more focused ultrasound transducers. The RE driver can comprise one or more power amplifiers including one or more III-V semiconductors, (e.g., gallium nitride GaN, GaAs, GaSb, InP, InAs, InSb, InGaAs, AlSb, AlGaAs, and/or AlGaN) field-effect transistors to efficiently provide high power with distinct narrow-band RE signals over a wide frequency range. The RE driver can include a power measurement and/or calibration system to monitor the amplitude and phase of the RE signal output from the power amplifier and estimate the amount of RE power delivered to the ultrasound transducers.

IPC Classes  ?

• A61N 7/02 - Localised ultrasound hyperthermia
• H03F 3/217 - Class D power amplifiers; Switching amplifiers
• H03F 3/193 - High-frequency amplifiers, e.g. radio frequency amplifiers with semiconductor devices only with field-effect devices

Abstract

Embodiments provide an ultrasound treatment system. In some embodiments, the system includes a removable transducer module having an ultrasound transducer. In some embodiments, the system can include a hand wand and a control module that is coupled to the hand wand and has a graphical user interface for controlling the removable transducer module, and an interface coupling the hand wand to the control module. The interface may provide power to the hand wand or may transfer a signal from the hand wand to the control module. In some embodiments, the treatment system may be used in cosmetic procedures on at least a portion of a face, head, neck, and/or other part of a patient.

IPC Classes  ?

• A61B 8/08 - Detecting organic movements or changes, e.g. tumours, cysts, swellings
• A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
• A61N 7/00 - Ultrasound therapy
• A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
• A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
• G10K 11/35 - Sound-focusing or directing, e.g. scanning using mechanical steering of transducers
• A45D 44/00 - Other cosmetic or toiletry articles, e.g. for hairdressers' rooms
• A45D 19/00 - Devices for washing the hair or the scalp; Similar devices for colouring the hair

Abstract

The present invention relates the use of botulinum toxin for the treatment of facial wrinkles, wherein botulinum toxin is administered at high doses (e.g., 50 U to 200 U) using small injection volumes (e.g., 0.05 ml to 0.35 ml). Furthermore, the present invention relates to a method for the treatment of facial wrinkles (e.g., glabellar frown lines) by injecting small volumes of a highly concentrated botulinum toxin solution into a target facial area of a subject.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)
• A61Q 19/08 - Anti-ageing preparations

Abstract

The present invention relates the use of botulinum toxin for the treatment of facial wrinkles, wherein botulinum toxin is administered at high doses (e.g., 50 U to 200 U) using small injection volumes (e.g., 0.05 ml to 0.35 ml). Furthermore, the present invention relates to a method for the treatment of facial wrinkles (e.g., glabellar frown lines) by injecting small volumes of a highly concentrated botulinum toxin solution into a target facial area of a subject.

IPC Classes  ?

• A61K 38/48 - Hydrolases (3) acting on peptide bonds (3.4)