Abstract

There is provided a fibrous mat comprising a plurality of electrospun fibers, wherein each of the electrospun fibers comprising a shell and a core comprising a water-soluble polymer and a plurality of cells, e.g., dormant cells or active cells. Further provided are methods of activating the dormant cells and method of use thereof, such as for supplementing a skin of the subject with a cosmeceutical ingredient.

IPC Classes  ?

• A61L 27/60 - Materials for use in artificial skin
• A61L 27/16 - Macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
• A61L 27/20 - Polysaccharides
• A61L 27/36 - Materials for prostheses or for coating prostheses containing ingredients of undetermined constitution or reaction products thereof
• A61L 27/54 - Biologically active materials, e.g. therapeutic substances
• A61L 27/56 - Porous or cellular materials

Abstract

There is provided a fibrous mat comprising a plurality of electrospun fibers, wherein each of the electrospun fibers comprising a shell and a core comprising a water- soluble polymer and a plurality of cells, e.g., dormant cells. Further provided are methods of activating the dormant cells and method of use thereof, such as for supplementing a skin of the subject with a cosmeceutical ingredient.

IPC Classes  ?

• D01D 5/24 - Formation of filaments, threads, or the like with a hollow structureSpinnerette packs therefor
• D01D 5/00 - Formation of filaments, threads, or the like
• D01D 5/28 - Formation of filaments, threads, or the like while mixing different spinning solutions or melts during the spinning operationSpinnerette packs therefor
• D01D 5/34 - Core-skin structureSpinnerette packs therefor
• D01F 1/02 - Addition of substances to the spinning solution or to the melt
• D01F 1/08 - Addition of substances to the spinning solution or to the melt for forming hollow filaments
• D01F 8/04 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from synthetic polymers

Abstract

There is provided a fibrous mat comprising a plurality of electrospun fibers, wherein each of the electrospun fibers comprising a shell and a core comprising a water- soluble polymer and a plurality of cells, e.g., dormant cells or active cells. Further provided are methods of activating the dormant cells and method of use thereof, such as for supplementing a skin of the subject with a cosmeceutical ingredient.

IPC Classes  ?

• A61K 9/70 - Web, sheet or filament bases
• A61K 35/66 - Microorganisms or materials therefrom
• A61K 35/68 - Protozoa, e.g. flagella, amoebas, sporozoans, plasmodium or toxoplasma
• A61K 35/74 - Bacteria
• A61K 35/741 - Probiotics
• A61K 35/742 - Spore-forming bacteria, e.g. Bacillus coagulans, Bacillus subtilis, clostridium or Lactobacillus sporogenes
• A61K 36/02 - Algae
• A61K 9/00 - Medicinal preparations characterised by special physical form
• A61K 47/26 - Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharidesDerivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
• A61K 47/32 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers
• A61K 47/38 - CelluloseDerivatives thereof
• C12N 11/04 - Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
• C12N 1/04 - Preserving or maintaining viable microorganisms

Abstract

Starch-based fibers, compositions comprising same, method of preparing said starch-based fibers, kits and methods for use of said starch-based fibers including but not limited to oral delivery of cells (e.g., probiotic microorganisms) and/or molecules of interest (e.g., nutrients) are provided.

IPC Classes  ?

• D01F 8/18 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from other substances
• A61K 9/00 - Medicinal preparations characterised by special physical form
• D01F 9/00 - Man-made filaments or the like of other substancesManufacture thereofApparatus specially adapted for the manufacture of carbon filaments
• D01D 7/00 - Collecting the newly-spun products
• A61K 35/747 - Lactobacilli, e.g. L. acidophilus or L. brevis
• D01D 5/00 - Formation of filaments, threads, or the like
• D01D 4/02 - Spinnerettes
• D01D 5/38 - Formation of filaments, threads, or the like during polymerisation
• A61K 9/70 - Web, sheet or filament bases
• D01F 1/10 - Other agents for modifying properties

Abstract

Multi-layered electrospun microfibers and/or microtubes, comprising cells and/or molecules of interest. The invention is further directed to compositions comprising said microfibers and/or microtubes and methods of use thereof in various applications.

IPC Classes  ?

• D01D 5/00 - Formation of filaments, threads, or the like
• D01D 5/34 - Core-skin structureSpinnerette packs therefor
• D01D 5/24 - Formation of filaments, threads, or the like with a hollow structureSpinnerette packs therefor

Abstract

Multi-layered electrospun microfibers and/or microtubes, comprising cells and/or molecules of interest. The invention is further directed to compositions comprising said microfibers and/or microtubes and methods of use thereof in various applications.

IPC Classes  ?

• D01D 5/34 - Core-skin structureSpinnerette packs therefor
• D01F 1/10 - Other agents for modifying properties
• D01F 8/04 - Conjugated, i.e. bi- or multicomponent, man-made filaments or the likeManufacture thereof from synthetic polymers
• A61K 9/70 - Web, sheet or filament bases

Abstract

Starch-based fibers, compositions comprising same, method of preparing said starch-based fibers, kits and methods for use of said starch-based fibers including but not limited to oral delivery of cells (e.g., probiotic microorganisms) and/or molecules of interest (e.g., nutrients) are provided.

IPC Classes  ?

• D01D 5/34 - Core-skin structureSpinnerette packs therefor
• C08B 31/04 - Esters of organic acids
• C08B 30/20 - Amylose or amylopectin
• C07C 53/02 - Formic acid
• D01F 11/00 - Chemical after-treatment of man-made filaments or the like during manufacture
• D01F 1/10 - Other agents for modifying properties
• D06M 101/04 - Vegetal fibres

Abstract

Provided are methods of petroleum sequestration, which use electrospun microtubes capable of sequestering the petroleum from the water, and method of depleting and optionally degrading petroleum from water using floating devices which comprise the electrospun microtube attached to a floating carrier.

IPC Classes  ?

• C02F 1/28 - Treatment of water, waste water, or sewage by sorption
• C02F 1/68 - Treatment of water, waste water, or sewage by addition of specified substances, e.g. trace elements, for ameliorating potable water
• C02F 3/10 - PackingsFillingsGrids
• C02F 3/34 - Biological treatment of water, waste water, or sewage characterised by the microorganisms used
• C02F 101/32 - Hydrocarbons, e.g. oil
• C02F 103/08 - Seawater, e.g. for desalination

Abstract

Provided are methods of petroleum sequestration, which use electrospun microtubes capable of sequestering the petroleum from the water, and method of depleting and optionally degrading petroleum from water using floating devices which comprise the electrospun microtube attached to a floating carrier.

IPC Classes  ?

• C02F 1/68 - Treatment of water, waste water, or sewage by addition of specified substances, e.g. trace elements, for ameliorating potable water
• C02F 3/34 - Biological treatment of water, waste water, or sewage characterised by the microorganisms used