Abstract

Provided is a composition for enhancing cognitive abilities and use thereof; wherein the composition consists essentially of royal jelly, Taiwan green propolis and soybean lecithin; and the cognitive abilities comprise memory, judgment, intuition, calculation, and reaction abilities.

IPC Classes  ?

• A61K 35/644 - BeeswaxPropolisRoyal jellyHoney
• A61K 36/48 - Fabaceae or Leguminosae (Pea or Legume family)CaesalpiniaceaeMimosaceaePapilionaceae
• A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Abstract

Provided is a composition for enhancing cognitive abilities and use thereof; wherein the composition consists essentially of royal jelly, Taiwan green propolis and soybean lecithin; and the cognitive abilities comprise memory, judgment, intuition, calculation, and reaction abilities.

IPC Classes  ?

• A61K 35/644 - BeeswaxPropolisRoyal jellyHoney
• A61K 31/201 - Carboxylic acids, e.g. valproic acid having a carboxyl group bound to an acyclic chain of seven or more carbon atoms, e.g. stearic, palmitic or arachidic acid having one or two double bonds, e.g. oleic or linoleic acid
• A61K 31/685 - Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
• A61K 36/8988 - Gastrodia
• A61P 25/00 - Drugs for disorders of the nervous system

Abstract

Macaranga tanarius preparation or extract for manufacturing a composition for enhancing immunity of an insect, particularly a bee. Also provided is a method for enhancing immunity of an insect, particularly a bee. The method comprises administering an effective amount of a composition of the present invention to the insect.

IPC Classes  ?

• A23L 33/105 - Plant extracts, their artificial duplicates or their derivatives
• A61K 36/47 - Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
• A61P 37/02 - Immunomodulators
• A23K 10/30 - Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hayAnimal feeding-stuffs from material of fungal origin, e.g. mushrooms
• A23K 20/10 - Organic substances
• A61K 8/49 - Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
• A61K 36/185 - Magnoliopsida (dicotyledons)

Abstract

The present invention relates to use of a compound of Formula (I), (II), (III), (V), (IX) or (X) for treatment of age-related macular degeneration (AMD), ischemic retinopathy, optic neuropathy, diabetic retinopathy, or diabetic macular edema: (see formula I, see formula II, see formula III, see formula V, see formula IX or see formula X)

IPC Classes  ?

• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• A61K 9/06 - OintmentsBases therefor
• A61K 9/08 - Solutions
• A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
• A61P 27/02 - Ophthalmic agents
• A61P 27/06 - Antiglaucoma agents or miotics
• A61P 27/12 - Ophthalmic agents for cataracts

Abstract

The present invention provides a method for treating an ocular disease in a subject in need thereof, comprising administering an effective amount of an extract of Taiwanese propolis (TP) or an active component thereof to the subject. Also provided is a pharmaceutical composition for treating an ocular disease, which comprises an effective amount of an extract of TP or an active component thereof, and a pharmaceutically acceptable carrier.

IPC Classes  ?

• A61K 35/24 - MucusMucous glandsBursaSynovial fluidArthral fluidExcretaSpinal fluid
• A61K 35/37 - Digestive system
• A61K 35/64 - Insects, e.g. bees, wasps or fleas
• A61K 35/644 - BeeswaxPropolisRoyal jellyHoney

Abstract

A method for treating an ocular disease in a subject in need thereof, comprising administering an effective amount of an extract of Taiwanese propolis or an active component thereof to the subject. And a pharmaceutical composition for treating an ocular disease, which comprises an effective amount of an extract of Taiwanese propolis or an active component thereof, and a pharmaceutically acceptable carrier.

IPC Classes  ?

• A61K 35/64 - Insects, e.g. bees, wasps or fleas
• A61P 27/02 - Ophthalmic agents
• A61P 27/06 - Antiglaucoma agents or miotics
• A61P 27/12 - Ophthalmic agents for cataracts

Abstract

The present invention provides a method for treating an ocular disease in a subject in need thereof, comprising administering an effective amount of a compound of Formula (A) to the subject. Also provided is a pharmaceutical composition for treating an ocular disease, which comprises compound of Formula (A), and a pharmaceutically acceptable carrier.

IPC Classes  ?

• A61K 31/35 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• A61K 9/00 - Medicinal preparations characterised by special physical form

Goods & Services

[ Make-up; cosmetic preparations for slimming purposes; cosmetic preparations for skin care; make-up removing preparations; tissues impregnated with make-up removing preparations; lotions for cosmetic purposes; beauty masks; cleansing milk for toilet purposes; cosmetic creams; cosmetic sunscreen preparations; dry shampoos; ] cleaning preparations; douching preparations for personal sanitary or deodorant purposes [ ; oils for cleaning purposes; volcanic ash for cleaning; Non-medicated bath preparations; bath salts ]

Goods & Services

[ Herbal teas for medicinal purposes; medicinal herbs; Medical preparations for slimming purposes; vaccines; vitamin preparations; mineral food supplements; ]nutritional supplements; propolis dietary supplements; propolis for medicinal or therapeutic purposes; [ protein dietary supplements; albumin dietary supplements; Dietetic sugar substitutes for medical use; protein supplements for animals; ferments for pharmaceutical purposes; flour for pharmaceutical purposes; ] royal jelly dietary supplements; royal jelly for medical purposes [ ; glucose dietary supplements; pollen dietary supplements; yeast dietary supplements; nutritionally fortified beverages for medical purposes; Beverages containing chlorophyll for use as a nutritional supplement; Dietary supplemental drinks in the nature of vitamin and mineral beverages ]

Goods & Services

[ Golden syrup; Maltose for food; molasses; sugar; sweetmeats; candy; honey; ]Propolis bee glue for human consumption [ ; royal jelly for food purposes; oat flakes; farinaceous food pastes for human consumption; muesli; cereal-based snack foods; ice cream; tea; tea-based beverages; coffee; coffee-based beverages; cocoa; cocoa-based beverages; cookies; sauces; seasonings; pastries ]

Goods & Services

[ Goods import-export agencies; business management assistance; business management consultancy; professional business consultation; commercial business management; commercial information agencies; commercial administration of the licensing of the goods and services of others; ] commercial information and advice for consumers; [ auctioneering; retail or wholesale store services for pharmaceutical, and sanitary preparations and medical supplies; ] Retail store services and wholesale store services for cosmetics, beverages, food and products featuring honey

Abstract

The present invention is directed to a novel use of prenylflavanone compounds for control of blood glucose and treatment or prevention of diabetes.

IPC Classes  ?

• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• C07D 311/32 - 2, 3-Dihydro derivatives, e.g. flavanones
• A61K 35/644 - BeeswaxPropolisRoyal jellyHoney

Abstract

The present invention is directed to a novel use of prenylflavanone compounds isolated from Taiwanese green propolis for control of blood glucose and treatment or prevention of diabetes. For instance, the prenylflavanone compounds are selected from PPC, PPD, PPF, PPG, PPI, PPA, PPB, Pokinawan, (S,E)-2-(3,4-dihydroxy-2-(7-hydroxy-3,7-dimethyloct-2-en-1-yl)phenyl)-5,7- dihydroxy -6-(3-hydroxy-3-methylbutyl)-3,4-dihydro-2H-1-benzopyran-4-one and (S)-2 -(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-((2E,6E)-11-hydroxy-3,7, 11-trimethyldodeca-2, 6-dien-1-yl)-3,4-dihydro-2H-1-benzopyran-4-one.

IPC Classes  ?

• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline
• A61K 35/644 - BeeswaxPropolisRoyal jellyHoney
• A61P 3/08 - Drugs for disorders of the metabolism for glucose homeostasis
• A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Abstract

The invention provides a method of changing a ratio of 68 to 64 kDa protein of MRJP3 in a royal jelly, a method of producing a royal jelly comprising MRJP3 having a changed ratio of 68 to 64 kDa protein relative to a control royal jelly and the royal jelly produced thereform. Also provided is a method of promoting the growth of the larva of a queen bee comprising feeding the larva of the queen bee a royal jelly of the invention. Further provided is a method of producing bee larva, pupa and queen bees with sizes larger than normal.

IPC Classes  ?

• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin
• A01K 53/00 - Feeding or drinking appliances for bees
• A61K 31/185 - AcidsAnhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
• A61K 35/644 - BeeswaxPropolisRoyal jellyHoney

Abstract

The invention provides a method of changing a ratio of 68 to 64 kDa protein of MRJP3 in a royal jelly, a method of producing a royal jelly comprising MRJP3 having a changed ratio of 68 to 64 kDa protein relative to a control royal jelly and the royal jelly produced thereform. Also provided is a method of promoting the growth of the larva of a queen bee comprising feeding the larva of the queen bee a royal jelly of the invention. Further provided is a method of producing bee larva, pupa and queen bees with sizes larger than normal.

IPC Classes  ?

• A23K 1/165 - with steroids, hormones, or enzymes
• A61K 31/352 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. cannabinols, methantheline

Abstract

Disclosed is a compound capable of promoting the growth and development of neurons, the proliferation of neural stem cells and inducing the neural stem cells to differentiate into neurons, which is represented by a general formula as (I). The compound of the present invention can increase the survival rate of neural cells even at a low cellular density in a culture medium. The compound of the present invention can also promote the growth of neurons, which is revealed by the increase in the thickness, length and number of branches in the neurites (neural fibers). In addition, the compound of the present invention can be used to promote the development of neural stem cells and induce them to differentiate into neurons.

IPC Classes  ?

• A61K 31/353 - 3,4-Dihydrobenzopyrans, e.g. chroman, catechin