The present invention addresses the problem of providing a relatively low-molecular compound capable of controlling necroptosis. Provided is an agent for treating a disease or condition that is improved by controlling necroptosis, the agent containing a compound represented by formula I or formula II or a pharmacologically acceptable salt thereof. (In formula I and formula II, each of R1, R2, and R31-61-6 alkyl, and X is H or COR4, R 41-622C=CH-.)
The purpose of the present invention is to provide a medium, in which cells to be used for producing a cultured meat can be proliferated, by adding a food material as an additive. The present inventors cultured cells with the use of food components as additives and, consequently, found that when whey was added as a cell proliferation promoting agent, fibroblasts, adipocytes and myoblasts exhibited high proliferation ability. Thus, the present invention, which pertains to a cell proliferation medium comprising a basic medium and whey as a cell proliferation promoting agent, has been completed.
The purpose of the present invention is to provide a culture medium in which cells to be used for producing a cultured meat can be grown, by adding thereto a food material as an additive. As a result of culturing cells using a food ingredient as an additive, it became possible to obtain high growth potential in fibroblasts and myoblasts by adding egg white or a dried product of egg white as a cell growth promoter. Accordingly, the present invention pertaining to a cell-growing culture medium containing a basic culture medium and egg white as a cell growth promoter was accomplished.
An assay device allows reducing manufacturing variation, maintaining the measurement accuracy of the assay device at a high level, and enhancing the liquid control performance. The assay device of the present invention includes a microfluidic channel 2 allowing liquid to flow, an absorbing porous medium 3 disposed at a distance from one end 2a of the microfluidic channel 2, a separating space 4 disposed between the microfluidic channel 2 and the absorbing porous medium 3, and a housing space 5 housing the absorbing porous medium 3. The assay device further includes a lower member 20 which is an integrally molded article constituting a part of the assay device. The lower member 20 defines a lower portion 2b of the microfluidic channel 2, a lower portion 4a of the separating space 4, and a lower portion 5a of the housing space 5. The lower portions 4a, 5a of the separating space 4 and the housing space 5 are inclined downward toward one side from the other side in a flow direction. The lower member 20 supports the absorbing porous medium 3 at the lower portion 5a of the housing space 5.
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
Provided is an estimation device with which it is possible to provide information relating to the cognitive function of a testee. The estimation device includes: a storage unit that stores a learned model trained so that when a meal history of a subject is input, the learned model outputs information about to which of a plurality of meal tendency groups the subject belongs, the meal tendency groups set in advance and including a high-grain meal group and a high-protein-balance meal group; an acquisition unit for acquiring the meal history of the subject; and an estimation unit for estimating to which of the plurality of meal tendency groups the subject belongs in response to input of the acquired meal history into the learned model.
G16H 20/60 - ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to nutrition control, e.g. diets
G16H 50/30 - ICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indicesICT specially adapted for medical diagnosis, medical simulation or medical data miningICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for individual health risk assessment
The present invention provides a foie gras substitute food product in which lipid separation is inhibited, and preferably other qualities (e.g., color retention, taste, juiciness, and smoothness) are also improved. A foie gras substitute food product according to the present invention comprises: (A1) vegetable protein and/or milk protein; (B) milk fat; (C) an O/W emulsifier; and (D) egg yolk. The contained amount of egg yolk that is the ingredient (D) is 5-20 mass% with respect to the total amount of the foie gras substitute food product. A method for producing a foie gras substitute food product according to the present invention comprises the following steps (1), (2), and (3), wherein the contained amount of egg yolk in a food composition in step (3) is 5-20 mass% with respect to the total amount of the foie gras substitute food product: (1) a step for preparing a hydrate containing water and (A) at least one protein selected from the group consisting of vegetable proteins, milk proteins, and egg proteins; (2) a step for preparing an emulsion containing (B) milk fat and (C) an O/W emulsifier; and (3) a step for mixing the hydrate obtained in step (1), the emulsion obtained in step (2), and, optionally, egg yolk to produce the food composition.
A23L 13/72 - Tenderised or flavoured meat piecesMacerating or marinating solutions specially adapted therefor using additives, e.g. by injection of solutions
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
NH FOODS LTD. (Japan)
Inventor
Fuchiwaki, Yusuke
Tanaka, Masato
Yamamura, Shohei
Morishita, Naoki
Kamiya, Kumiko
Matsuzaki, Seiichiro
Abstract
An assay device and an assay method are each capable of ensuring the accuracy of a target substance detection section. The assay device includes a plurality of assay units 100, each assay unit 100 including a microfluidic channel configured to allow a liquid to flow; a porous absorbing medium disposed at a distance from one end of the microfluidic channel, the one end being located on one side in a flow direction of the liquid; and a separation space disposed between the one end of the microfluidic channel and the porous absorbing medium, in which the microfluidic channel includes, in the microfluidic channel, a detection section 14 having immobilized thereon a substance capable of specifically reacting with a target substance, and an internal standard section 54 having immobilized thereon an internal standard substance, and each assay unit includes two parallel ventilation passages that are respectively adjacent to both sides of the microfluidic channel in the width direction orthogonal to the flow direction, the two parallel ventilation passages communicating with the microfluidic channel to allow for air circulation.
National Agriculture and Food Research Organization (Japan)
Inventor
Okuda, Masaki
Uchida, Daisuke
Sukegawa, Shin
Fuchimoto, Daiichiro
Matsumoto, Mitsuhito
Abstract
A pig rearing support apparatus includes: an acquirer configured to acquire image data of an image captured by a camera unit installed facing a pen in which sows are raised in a group; a detector configured to detect mounting behavior of the sows based on the image of the image data; and a count processor configured to count the number of times the mounting behavior is detected within a preset observation period. Such a pig rearing support apparatus can inform a breeder at the right time without involving excessive cost or labor whether there is any sow that shows estrus symptoms among sows being raised in a group in a pen.
The present invention provides a means for regulating (promoting or suppressing) the growth of Decapoda crustaceans such as shrimps and crabs. Methods of the present invention regulate the growth of animals belonging to the Decapoda, comprising a step of regulating (inhibiting or enhancing) the function of genes comprising: at least one growth regulation-related gene selected from the group consisting of mTOR pathway, Akt pathway, and upstream and downstream factors of the pathways; and further optionally at least one molting-related gene selected from a molting-related factor or the function of a transcription or translation product of the genes.
Provided is a component capable of effectively increasing intracerebral GABA. An agent for increasing intracerebral γ-aminobutyric acid (GABA), the agent containing a compound represented by formula I. (In the formula, R is a side chain of an amino acid that is acceptable as a pharmaceutical or food product.)
A61K 31/195 - Carboxylic acids, e.g. valproic acid having an amino group
A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
A61K 31/4172 - Imidazole-alkanecarboxylic acids, e.g. histidine
An examination kit according to the present invention, which provides an improved means for detecting a peanut allergen remaining in a food product or on a food product processing device, is for quantitatively or qualitatively detecting a peanut allergen remaining in a food product or on a food product processing device by an immunoassay method and includes an anti-Ara h 3 antibody or an antigen binding fragment (anti-Ara h 3 antibody or the like) therefor. An examination method for a peanut allergen in a food product according to the present invention includes: (1) a step for extracting peanut proteins remaining in a food product or on a food product processing device; and (2) a step for quantitatively or qualitatively detecting the Ara h 3 protein in the obtained extract by an immunoassay method using an anti-Ara h 3 antibody or the like.
In order to obtain muscle tissue-derived cells for use in the production of cultured meat, it is necessary to culture proliferative myoblasts and muscle satellite cells. However, these cells easily differentiate, and have a tendency, even in normal culture conditions, to differentiate to myotube cells which are not proliferative. Here, the objective of the present invention is to identify a component that inhibits differentiation of myoblasts and muscle satellite cells in order to culture a large amount of muscle tissue-derived cells for production of cultured meat. Food components used as additives were studied for differentiation suppressing effect, and the study revealed that when whey was added, differentiation of myoblasts and muscle satellite cells was successfully suppressed, and thus a differentiation suppressing agent is provided.
The purpose of the present invention is to provide a medium, in which cells to be used for producing a cultured meat can be proliferated, by adding a food material as an additive. The present inventors cultured cells with the use of food components as additives and, consequently, found that when whey was added as a cell proliferation promoter, fibroblasts, adipocytes and myoblasts exhibited high proliferation ability. Thus, the present invention, which pertains to a cell proliferation medium comprising a basic medium and whey as a cell proliferation promoter, has been completed.
NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT (Japan)
NH Foods Ltd. (Japan)
Inventor
Ayabe, Ayako
Hasegawa, Takanori
Matsumoto, Kenji
Morita, Hideaki
Abstract
The present invention provides highly effective and safe means capable of preventing or treating an egg allergy in infants. An oral immunotolerance agent or a food composition for preventing or treating an egg allergy according to the present invention contains a degraded product of heat-denatured egg white with an aspartic protease (e.g. pepsin) or a metal protease (e.g. thermolysin).
The present invention provides an improved means for extracting a protein in foods, which is capable of solving problems such as safety, speed, and reliability. The extraction reagent of the present invention is a reagent for extracting a protein in foods that includes a reducing agent and a surfactant. The reducing agent is a mercaptoalkanol and/or a sulfite, the surfactant is an alkyl sulfate, and the extraction reagent is for treatment by a shake method for from 30 minutes to 8 hours. The test kit of the present invention includes the extraction reagent and a specific antibody to a target protein for quantitatively or qualitatively detecting a target protein by an immunological measurement method.
NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (Japan)
Inventor
Okuda, Masaki
Uchida, Daisuke
Sukegawa, Shin
Fuchimoto, Daiichiro
Matsumoto, Mitsuhito
Abstract
This swine rearing assistance apparatus is provided with: an acquisition unit that acquires image data of an image captured by a camera unit disposed so as to be directed towards a pen in which female swine are being raised in a group; a detection unit that detects a mounting behavior of the female swine on the basis of the image of the image data; and a count unit that counts the number of times the mounting behavior has been detected during a preset observation time. With such a swine rearing assistance apparatus, it is possible to notify, in a timely fashion without requiring excessive cost or labor, rearing staff of whether or not any of the female swine being reared in the pen are showing signs of heat.
This pig rearing assistance apparatus is provided with: an acquisition unit that acquires image data of an image captured by a camera directed to a plurality of pens in each of which a group of pigs are being raised; a detection unit that detects a specific posture of the pigs on the basis of the image of the image data; and a count unit that counts the number of times of the specific posture detected for each of the plurality of pens during a preset observation time. This pig rearing assistance apparatus can notify rearing staff of which pen includes a pig having a poor health condition among the plurality of pens in each of which the group of pigs are being raised at an appropriate timing without excessive cost and labor.
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
NH FOODS LTD. (Japan)
Inventor
Fuchiwaki, Yusuke
Tanaka, Masato
Yamamura, Shohei
Morishita, Naoki
Matsuzaki, Seiichiro
Abstract
The present invention provides an assay device wherein manufacturing variations are minimized, a high measurement accuracy of the assay device is maintained, and the liquid-controlling performance is improved. This assay device has a microchannel 2 for channeling a liquid, an absorption porous medium 3 positioned across a gap from one end part 2a of the microchannel 2, a separation space 4 between the microchannel 2 and the absorption porous medium 3, and an accommodation space 5 for accommodating the absorption porous medium 3. The assay device also has a lower member 20 that is an integral molded article constituting a part thereof. The lower member 20 defines the lower part 2b of the microchannel 2, the lower part 4a of the separation space 4, and the lower part 5a of the accommodation space 5. The lower parts 4a, 5a of the separation space 4 and the accommodation space 5 incline downward from the other side to one side with respect to the flow direction. The lower member 20 supports the absorption porous medium 3 at the lower part 5a of the accommodation space 5.
G01N 37/00 - Details not covered by any other group of this subclass
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
22.
METHOD FOR REGULATING GROWTH OF DECAPODA CRUSTACEANS
The present invention provides a means for regulating (accelerating or suppressing) growth of Decapoda crustaceans such as shrimp and crab. The method according to the present invention is for regulating growth of animals belonging to the order Decapoda and comprises a step for regulating (inhibiting or enhancing) functions of genes including at least one growth regulation-related gene selected from the group consisting of those involved in the mTOR pathway and the Akt pathway, and upstream and downstream factors thereof, and optionally further including at least one ecdysis-related gene selected from ecdysis-related factors, or functions of transcription products or translation products of said genes.
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
NH FOODS LTD. (Japan)
Inventor
Fuchiwaki, Yusuke
Tanaka, Masato
Yamamura, Shohei
Morishita, Naoki
Kamiya, Kumiko
Matsuzaki, Seiichiro
Abstract
Provided are an assay device and an assay method with which the accuracy of a target substance detection unit can be ensured. An assay device comprises a plurality of assay units 100, the assay units 100 each comprising: a micro channel configured such that a liquid can flow therethrough; an absorptive porous medium that is disposed spaced apart from one end of the micro channel which is positioned at one side in a flow direction of the liquid; and a separation space that is disposed between the one end of the micro channel and the absorptive porous medium. The micro channel comprises, inside the micro channel, a detection section 14 in which a substance that is capable of specifically reacting with a target substance is immobilized, and an internal reference section 54 in which an internal reference substance is immobilized. The assay device further comprises two side ventilation passages that are adjacent to both sides of the micro channel in a width direction orthogonal to the flow direction so as to communicate with the micro channel, and that allow air to flow therethrough.
G01N 37/00 - Details not covered by any other group of this subclass
G01N 35/08 - Automatic analysis not limited to methods or materials provided for in any single one of groups Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals
NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
NH FOODS LTD. (Japan)
Inventor
Fuchiwaki, Yusuke
Tanaka, Masato
Yamamura, Shohei
Morishita, Naoki
Kamiya, Kumiko
Matsuzaki, Seiichiro
Abstract
[Problem] To provide an assay system whereby a plurality of liquids are rapidly and consecutively supplied, a miniscule amount of liquid is supplied at high precision, the configuration for supplying liquid is simplified, the handling of liquid is simplified, and risk of contamination is reduced. [Solution] The present invention pertains to an assay system including an assay device 10 that performs assay by using a liquid L. This assay system comprises: a liquid supply device 20, 120 that drips liquid onto an assay device; a movement device 30 that moves the assay device; and a control device 40, 140 that controls the liquid supply device and the moving device. The liquid supply device includes a plurality of containers 21 respectively formed in the shape of an instillation container, and has at least one movable member 23a, 123a that pushes main bodies of the multiple containers such that liquid is dripped from discharge ports 21c of the multiple containers. The control device controls the at least one movable member so as to push the main bodies of the plurality of containers in a desired order and at a desired timing.
NATIONAL CENTER FOR CHILD HEALTH AND DEVELOPMENT (Japan)
NH FOODS LTD. (Japan)
Inventor
Ayabe Ayako
Hasegawa Takanori
Matsumoto Kenji
Morita Hideaki
Abstract
The present invention provides a highly effective and safe means capable of preventing or treating egg allergy in infants. According to the present invention, an oral immunotolerant or a food composition for preventing or treating egg allergy contains a degradation product of egg white heat-denatured by aspartic protease (for example, pepsin) or metalloprotease (for example, thermolysin).
NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (Japan)
NH FOODS LTD. (Japan)
Inventor
Takenouchi Takato
Uenishi Hirohide
Kitani Hiroshi
Morozumi Takeya
Nishiyama Yasutaka
Abstract
The discovery has been made that immortalized cells derived from porcine kidney macrophages exhibit a high infection susceptibility for various pig infectious virus strains, which has made it possible to provide, inter alia, a method for growing pig infectious viruses using the cells.
Provided is a feature for accurately determining estrus of sows without relying on experience or intuition of an observer. This estrus determination device for sows comprises a measuring unit that measures the frequency of waking up and going to sleeping per unit time of a sow kept in a stall, and a determination unit that determines estrus of the sow on the basis of a plurality of said frequencies repeatedly measured by the measuring unit over a set period of time.
Provided is a feature that easily evaluates the extent of growth of pigs housed in a group without having to guide the pigs one by one to a cage. This growth evaluation device comprises an extraction unit that extracts a buttocks image in which the buttocks of a pig is shown from right behind from images captured by a camera installed toward a pen in which a plurality of pigs is group-housed, a calculation unit that calculates the buttocks width from the buttocks image, and an evaluation unit that evaluates the extent of growth of the entire plurality of pigs on the basis of a predetermined number or more of the buttock widths calculated by the calculation unit.
National Agriculture and Food Research Organization (Japan)
Inventor
Takeuchi, Eri
Urayama, Kana
Matsumoto, Takashi
Morioka, Kazuki
Yamakawa, Makoto
Yoshida, Kazuo
Kanno, Toru
Fukai, Katsuhiko
Abstract
30 alkyl group. These groups may include a substituent group); wherein the agent is capable of suppressing immune reaction inhibitory action caused by a body fluid in an immunoassay sample.
NATIONAL AGRICULTURE AND FOOD RESEARCH ORGANIZATION (Japan)
Inventor
Hojo, Eri
Urayama, Kana
Matsumoto, Takashi
Morioka, Kazuki
Yamakawa, Makoto
Yoshida, Kazuo
Kanno, Toru
Fukai, Katsuhiko
Abstract
The purpose of the present invention is to: provide an agent that effectively suppresses inhibition of antigen-antibody reaction in an immunoassay using a sample containing a body fluid, in particular, a component derived from a biological mucosal membrane, such as saliva; and to suppress false positive and false negative results in the immunoassay. The present invention provides an immune reaction inhibition suppressing agent that suppresses immune reaction inhibition action derived from a body fluid in an immunoassay sample, the immune reaction inhibition suppressing agent being characterized by including either compound (1) or (2). (1) Sulfonic acid compound represented by the formula R1-SO3H or a salt thereof. (In the formula, R1 is: a straight-chain C5-C30 alkyl group; a straight-chain C1-C30 alkyl group substituted by a carbocyclic aromatic group having at least one C5-C30 alkyl group; or a carbocyclic aromatic group having at least one straight-chain C5-C30 alkyl group. These groups may include a substituent group.) (2) Quaternary ammonium ion represented by the formula N+-R2R3R4R5 or a salt thereof. (In the formula, R2-R5 are each independently a straight-chain C1-C30 alkyl group, or a carbocyclic aromatic group substituted by at least one straight-chain C5-C30 alkyl group. These groups may include a substituent group.)
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Edible oils and fats; milk products; meat; fresh, chilled or
frozen edible aquatic animals (not live); processed meat
products; sausages; deep-fried chicken (Karaage); hamburg
steaks; skewered and grilled chicken (Yakitori); breaded
pork cutlet (Tonkatsu); extracts of meat; deep-fried meat in
batter (Tempura of meat); deep-fried seafood in batter
(Tempura of seafood); deep-fried vegetables in batter
(Tempura of vegetables); mixture of vegetables and other
ingredients fried in batter, vegetables predominating
(Kakiage); prepared food consisting mainly of meat, fish,
poultry or vegetables; instant dish consisting mainly of
cooked meat, vegetables, seafood with addition of
seasonings; processed seafood products; pre-cooked curry
stew, stew and soup mixes; soups for Chinese noodles;
extracts for soup of Chinese noodles. Bread and buns; sandwiches; Chinese-style steamed buns;
hamburgers [sandwiches]; pizzas; hot dogs [sandwiches]; meat
pies; seasonings; spices; Chinese stuffed dumplings (Gyoza);
Chinese steamed dumplings (Shumai); sushi; ravioli; rice
casserole with white sauce; pasta sauce.
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Edible oils and fats; milk products; meat; fresh, chilled or
frozen edible aquatic animals (not live); processed meat
products; sausages; deep-fried chicken (karaage); Hamburg
steaks; skewered and grilled chicken (yakitori); breaded
pork cutlet (tonkatsu); extracts of meat; deep-fried meat in
batter (tempura of meat); deep-fried seafood in batter
(tempura of seafood); deep-fried vegetables in batter
(tempura of vegetables); mixture of vegetables and other
ingredients fried in batter (kakiage), vegetables
predominating; prepared food consisting mainly of meat,
fish, poultry or vegetables; instant dish consisting mainly
of cooked meat, vegetables, seafood and seasonings;
processed seafood products; pre-cooked curry stew, stew
mixes, being instant stew and soup mixes; soups for Chinese
noodles; extracts for soup of Chinese noodles. Bread and buns; sandwiches; Chinese-style steamed buns;
hamburgers; pizzas; hot dogs; meat pies; seasonings; spices;
Chinese stuffed dumplings (gyoza); Chinese steamed dumplings
(shumai); sushi; ravioli; rice casserole with white sauce;
pasta sauce.
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Milk products excluding ice cream, ice milk and frozen yogurt; Meat; Fresh, chilled and frozen edible aquatic animals not live, namely, seafood not live; Processed meat products; Sausages; Deep-fried chicken (Karaage); Hamburger steaks; Skewered and grilled chicken (Yakitori); Breaded pork cutlet (Tonkatsu); Extracts of meat; Deep-fried meat in batter (Tempura of meat); Deep-fried seafood in batter (Tempura of seafood); Deep-fried vegetables in batter (Tempura of vegetables); cooked vegetables, namely, mixture of vegetables and other ingredients fried in batter (Kakiage); Prepared food consisting mainly of meat, fish, poultry or vegetables, namely, prepared food kits composed of meat, poultry, fish, seafood, and/or vegetables and also including sauces or seasonings, ready for cooking and assembly as a meal, Prepared meat, Prepared dishes consisting primarily of fishcakes, boiled eggs, vegetables, and broth; Instant dish consisting mainly of cooked meat, vegetables, seafood and seasonings, namely, instant pre-cooked soup, prepared entrees consisting primarily of meat, fish, poultry or vegetables; Processed seafood products, namely, tinned seafood, processed seafood, frozen seafood; Pre-cooked curry stew, stew and soup mixes; Soups of Chinese noodles; Extracts of soup of Chinese noodles Bread and buns; Sandwiches; Chinese-style steamed buns stuffed with minced meat; Hamburger sandwiches; Pizzas; Hot dog sandwiches; Meat pies; Seasonings; Spices; Chinese stuffed dumplings (Gyoza); Chinese steamed dumplings (Shumai); Sushi; Ravioli; Rice casserole with white sauce; Pasta sauce
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
(1) Edible oils and fats; milk products; meat; fresh, chilled and frozen edible aquatic animals, namely, fish, squid, crab, lobster, prawn, shrimp, clam, octopus, sea urchins; processed meat products, namely, canned meat, prepared meat, frozen meat dinners, meat pies, dried meat, sausages, hams, bacons; sausages; deep-fried chicken (Karaage); hamburg steaks; skewered and grilled chicken (Yakitori); breaded pork cutlet (Tonkatsu); extracts of meat; deep-fried meat in batter (Tempura of meat); deep-fried seafood in batter (Tempura of seafood); deep-fried vegetables in batter (Tempura of vegetables); Kakiage, namely, a mixture of vegetables and meat fried in batter; Kakiage, namely, a mixture of vegetables and seafood fried in batter; prepared meals primarily consisting of meat, fish, poultry and vegetables; instant dish consisting mainly of cooked meat, vegetables, seafood and seasonings; processed seafood products, namely, canned tuna fish, fish sausages, fish pies, fish preserves, blocks of boiled, smoked and then dried bonitos [Katsuo-bushi], dried pieces of agar jelly [Kanten], flakes of dried fish meat [Kezuri-bushi]; pre-cooked curry stew, stew and soup mixes.
(2) Bread and buns; sandwiches; Chinese-style steamed buns; hamburgers; pizzas; hot dogs; meat pies; seasonings; soups of Chinese noodles; extracts of soup of Chinese noodles; spices; Chinese stuffed dumplings (Gyoza); Chinese steamed dumplings (Shumai); sushi; ravioli; rice casserole with white sauce; pasta sauce.
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (Japan)
NH FOODS LTD. (Japan)
NATIONAL CENTER OF NEUROLOGY AND PSYCHIATRY (Japan)
Inventor
Hisatsune Tatsuhiro
Totsuka Mamoru
Satsu Hideo
Kaneko Jun
Katakura Yoshinori
Sato Mikako
Matsumoto Takashi
Morimatsu Fumiki
Imabayashi Etsuko
Matsuda Hiroshi
Abstract
Provided is a natural-derived antiaging agent. The antiaging agent comprises as an active ingredient at least one member selected from the group consisting of imidazole dipeptides and metabolites thereof. Also provided is an agent for improving neuropsychological functions, said agent comprising as an active ingredient at least one member selected from the group consisting of imidazole dipeptides and metabolites thereof. Also provided are: an agent for changing the expression of a transporter such as SLC23A2, said agent comprising at least one member selected from the group consisting of imidazole dipeptides and metabolites thereof; an agent for regulating the concentration of a cytokine such as IP-10 in blood, said agent comprising at least one member selected from the group consisting of imidazole dipeptides and metabolites thereof; a method for detecting an improvement or worsening in neuropsychological functions; and a kit for detecting an improvement or worsening in neuropsychological functions.
A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
A61P 43/00 - Drugs for specific purposes, not provided for in groups
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
Broth for noodles in the form of powder and liquid; Edible oils and fats; Milk products; Meat for human consumption [fresh, chilled or frozen]; Eggs; Fresh, chilled or frozen edible aquatic animals (not live); Frozen vegetables; Frozen fruits; Tonkatsu (Deep-fried breaded pork); Hamburger patties; Yakitori (Japanese style char-broiled chicken); Chinese-style barbecued pork; Seasoned beef and pork liver and plucks; Processed meat products; Processed seafood products; Coconut milk; Ham salad; Processed vegetables and fruits; Fried tofu pieces (Abura-age); Freeze-dried tofu pieces (Kohri-dofu); Jelly made from devils' tongue root (Konnyaku); Soya milk [milk substitute]; Tofu consisting mainly of soya milk and collagen; Tofu; Fermented soybeans [Natto]; Processed eggs; Instant vegetable dish consisting of shrimps, carrots, young corns and seasonings cooked with fresh broccoli; Instant vegetable dish consisting of bacons, carrots, cheese and seasonings cooked with fresh asparagus; Instant vegetable dish consisting of bacons, carrots and seasonings cooked with fresh potato; Instant vegetable dish consisting of meats, processed meat products, edible aquatic animals and seasonings cooked with fresh vegetables; Hashed beef mixes; Instant miso soup; Prepared soup; Pre-cooked curry stew, stew and soup mixes; Ingredients for instant bowl of rice with a chop-suey-like mixture on it; Ingredients for instant Chinese dish of fried egg and crab; Ingredients for instant Chinese dish of tofu, vegetables and a spicy sauce (Tofu with vegetable in brown hot sauce); Ingredients for instant Chinese dish of eggplant and a spicy sauce; Ingredients for instant Chinese dish of bean vermicelli and a spicy sauce; Ingredients for instant Chinese dish of twice cooked pork (Szechuan dish); Ingredients for instant Chinese dish, called happosai; Ingredients for instant Chinese dish of sweet and sour pork; Ingredients for instant Chinese dish of sweet and chili shrimp; Ingredients for instant Chinese dish of fried chopped chicken with cashew nuts; Ingredients for instant Chinese dish of Green pepper steak called Chinjao Rosu; Instant dish consisting mainly of cooked meats, vegetables, edible aquatic animals and seasonings; Dried flakes of laver for sprinkling on rice in hot water [Ochazuke-nori]; Furi-kake [dried flakes of fish, meat, vegetables or seaweed]; Side-dish made of fermented soybean (Name-mono); Collagen peptide for human consumption; Collagen for human consumption; Protein for human consumption; Assorted ingredients for one-pot dish and/or barbecue consisting of meats, edible aquatic animals and/or processed vegetables; Fried chicken; Prepared food consisting mainly of meat or processed meat products; Prepared food consisting mainly of edible aquatic animals; Prepared food consisting mainly of vegetables; Prepared food consisting mainly of fruits; Prepared food consisting mainly of Tofu; Prepared food consisting mainly of egg; Scotch eggs. Bean-starch vermicelli salad; Binding agents for ice cream; Meat tenderizers for household purposes; Preparations for stiffening whipped cream; Aromatic preparations for food [not from Essential oils]; Tea; Coffee-based beverage; Cocoa-based beverage; Ice; Breads with sausage in their center core; Bagels; Naan; Tortilla; Ciabatta; Chapati; English muffin; Scones; Croissant; Focaccia; Pita bread; French Sourdough bread (Pain de champagne); Vienna bread (Pain viennois); Brioche; Donuts; Curry breads; Sweets consisting mainly of coconut milk; Confectionery; Bread and buns; Seasonings for noodles; Instant spicy sauce (mapo sauce) mixes for Sichuan style bean curd; Instant spicy sauce (mapo sauce) mixes for bean starch vermicelli; Sauce for steam vegetable dish; Sauce for tonkatsu (Sauce for deep-fried breaded pork); Seasonings (other than spices); Spices; Ice cream mixes; Sherbet mixes; Unroasted coffee beans; Noodle-based prepared meals with their ingredients, broth or sauce; Noodle-based prepared meals; Bean-starch vermicelli with its ingredient for sautéed bean-starch vermicelli; Rice noodle with its ingredient for sautéed rice noodle; doughs; Cereal preparations; Almond paste; Chinese stuffed dumplings [Gyoza, cooked]; Sandwiches; Chinese steamed dumplings [Shumai, cooked]; Sushi; Fried balls of batter mix with small pieces of octopus [Takoyaki]; Chinese-style steamed bun; Hamburgers (prepared); Pizzas; Boxed lunches consisting of rice, with added meat, fish or vegetables; Hot dogs (sandwiches) [prepared]; Meat pies [prepared]; Ravioli [prepared]; Prepared ham and cheese sandwich (Croque monsieur); Tartine [prepared]; Wraps [prepared]; Bagel with ham and cheese; English muffin with ham and cheese; Ciabatta with sauce and cheese; Tortilla with roast chickens; Naan with sausage; Breads with meats, edible aquatic animals, vegetables, cheese or the like; Steamed dumplings (Xiaolongbao); Steamed Chinese chives bun; Chinese rice cakes wrapped in bamboo leaves; Spring rolls; Yeast powder; fermenting malted rice [Koji]; Yeast; Baking powder; Instant bread mixes; Instant confectionery mixes; Sauce for pasta; By-product of rice for food [sake lees]; Husked rice; Husked oats; Husked barley; Wheat flours mixed with seasonings and spices; Flour for food.
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
31 - Agricultural products; live animals
32 - Beers; non-alcoholic beverages
33 - Alcoholic beverages other than beer
37 - Construction and mining; installation and repair services
39 - Transport, packaging, storage and travel services
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Reagent kits for detecting toxic mold in foods; reagent kits for detecting food allergens; reagent kits for detecting source of food poisoning; reagent kits for detecting toxin of food poisoning; collagen for use in cosmetics; collagen peptide for use in cosmetics; plant growth regulating preparations; fertilizers; higher fatty acids; artificial sweeteners; food enriching preparations consisting mainly of collagen; degreasers other than for use in manufacturing processes; rust removing preparations; fabric softeners for laundry use; laundry bleach; dentifrices; cosmetics; toiletries, namely, body soap, hair shampoo and conditioner, toothpaste; perfumery; false nails; false eyelashes; pharmaceutical, veterinary and sanitary preparations, namely, pharmaceutical preparations for the relief of pain, pharmaceutical preparations for the treatment of allergies, pharmaceutical preparations for the treatment of cancer, pharmaceutical preparations for the treatment of cardiovascular diseases, pharmaceutical preparations for the treatment of immunologic diseases, namely, autoimmune diseases, immunologic deficiency syndromes, veterinary pharmaceutical preparations for the treatment of vitamin deficiencies, veterinary pharmaceutical preparations for the treatment of infectious diseases, namely, respiratory infections, eye infections, topical infections; lacteal flour for babies; foods for babies; powdered milk for babies; dietetic foods adapted for medical purposes, namely, meal replacement bars for promoting weight loss; dietetic beverages adapted for medical purposes, namely, herbal tea for promoting weight loss; foods in the form of powders to add thickness consisting mainly of polysaccharide for the people with dysphagia; collagen peptide for medical purposes; dietary supplements for humans, namely, vitamins, minerals, lecithin; dietary supplements for promoting weight loss; dietary supplements for general health and well-being; lactobacillus-based dietary supplements for humans; collagen-based dietary supplements for humans; glucosamine-based dietary supplements for humans; Korean ginseng-based dietary supplements for humans; elastin-based dietary supplements for humans; placenta extract-based dietary supplements for humans; dietary supplements for humans consisting mainly of borage oil, pork hydrolysate and safflower; dietary supplements for humans consisting mainly of powdered chicken gristle; chicken extract-based dietary supplements for humans; dietary supplements for humans consisting mainly of carnosine and anserine; dietary supplements for humans consisting mainly of edible aquatic animals and edible seaweeds; dietary supplements for humans consisting mainly of amino acid, lecithin and herbs; dietary supplements for humans consisting mainly of isomaltooligosaccharide and alimentary fiber; propolis extract-based dietary supplements for humans; royal jelly-based dietary supplements for humans; animal semen for artificial insemination; human semen for artificial insemination; protective helmets for sports; downloadable image files; electronic publications; pacifiers for babies; ice bag pillows, for medical purposes; triangular bandages; supportive bandages; surgical catguts; feeding cups for medical purposes; dropping pipettes for medical purposes; teats; ice bags for medical purposes; medical ice bag holders; baby bottles; nursing bottles; cotton swabs for medical use; finger guards for medical purposes; artificial tympanic membranes; ear plugs for sleeping; ear plugs for soundproofing; gloves for medical purposes; ear picks; milk products; meat for human consumption, fresh, chilled and frozen; eggs; fresh, chilled and frozen edible aquatic animals, namely, fish, squid, crab, lobster, prawn, shrimp, clam, octopus; frozen vegetables; frozen fruits; deep-fried breaded pork [Tonkatsu]; hamburger patties; Japanese style char-broiled chicken [Yakitori]; Chinese-style barbecued pork; seasoned beef and pork liver and plucks; processed meat products, namely, canned meat, prepared meat, frozen meat dinners, meat pies, ham, sausage, bacon, dried meat, croquettes, bottled meat, boiled meat, grilled meat, fried meat, smoked meat, pickled meat; processed seafood products, namely, canned seafood, tuna fish, fish sausages, fish pies, fish preserves, boiled seafood, grilled seafood, fried seafood, smoked seafood, pickled seafood; coconut milk; ham salad; bean-starch vermicelli salad; processed vegetables and fruits; fried tofu pieces [Abura-age]; freeze-dried tofu pieces [Kohri-dofu]; jelly made from devils' tongue root [Konnyaku]; soya milk, milk substitute; tofu consisting mainly of soya milk and collagen; tofu; fermented soybeans [Natto]; processed eggs; instant vegetable dish consisting of shrimps, carrots, young corns and seasonings cooked with fresh broccoli; instant vegetable dish consisting of bacons, carrots, cheese and seasonings cooked with fresh asparagus; instant vegetable dish consisting of bacons, carrots and seasonings cooked with fresh potato; instant vegetable dish consisting of meats, processed meat products, edible aquatic animals and seasonings cooked with fresh vegetables; hashed beef mixes; instant spicy sauce (mapo sauce) mixes for Sichuan style bean curd; instant spicy sauce (mapo sauce) mixes for bean starch vermicelli; instant miso soup; prepared soup; pre-cooked curry stew, stew and soup mixes; prepared meals, namely packaged meal kits consisting primarily of sauces and seasonings and one and more of the following; rice, egg, crab, vegetables, vermicelli, pork, shrimp, chicken, beef, fish, squid, lobster, prawn, clam, octopus; instant dish consisting mainly of cooked meats, vegetables, edible aquatic animals and seasonings; dried flakes of laver for sprinkling on rice in hot water [Ochazuke-nori]; dried flakes of fish, meat, vegetables and seaweed [Furi-kake]; side-dish made of fermented soybean, [Name-mono]; raw pulses; collagen peptide for human consumption; collagen for human consumption; protein for human consumption; assorted ingredients for one-pot dish and/or barbecue consisting of meats, edible aquatic animals and/or processed vegetables; fried chicken; prepared food consisting mainly of meat and processed meat products; prepared food consisting mainly of edible aquatic animals; prepared food consisting mainly of vegetables; prepared food consisting mainly of fruits; prepared food consisting mainly of tofu; prepared food consisting mainly of egg; binding agents for ice cream; meat tenderizers for household purposes; preparations for stiffening whipped cream; aromatic preparations for food, not from 'essential oils'; tea; coffee-based beverage; cocoa-based beverage; ice; breads with sausage in their center core; bagels; naan; tortilla; ciabatta; chapati; English muffin; scones; croissant; focaccia; pita bread; pain de campagne; pain viennois; brioche; donuts; curry breads; sweets consisting mainly of coconut milk; confectionery; bread and buns; broth for noodles in the form of powder and liquid; seasonings for noodles; sauce for steam vegetable dish; sauce for tonkatsu, sauce for deep-fried breaded pork; seasonings, other than spices; spices; ice cream mixes; sherbet mixes; unroasted coffee beans; noodle-based prepared meals with their ingredients, broth and sauce; noodle-based prepared meals; bean-starch vermicelli with its ingredient for sautéed bean-starch vermicelli; rice noodle with its ingredient for sautéed rice noodle; doughs; breakfast cereals, processed cereals, ready-to-eat cereals; almond paste; Chinese stuffed dumplings [Gyoza, cooked]; sandwiches; Chinese steamed dumplings [Shumai, cooked]; sushi; fried balls of batter mix with small pieces of octopus [Takoyaki]; Chinese-style steamed bun; hamburgers, prepared; pizzas; boxed lunches consisting of rice, with added meat, fish and vegetables; hot dogs (sandwiches) [prepared]; meat pies, prepared; ravioli, prepared; croque monsieur, prepared; tartine, prepared; wraps, prepared; bagel with ham and cheese; English muffin with ham and cheese; ciabatta with sauce and cheese; tortilla with roast chickens; naan with sausage; bread, namely, bread containing meat, fish, vegetables and cheese; Scotch eggs; xiaolongbao; steamed Chinese chives bun; Chinese rice cakes wrapped in bamboo leaves; spring rolls; yeast powder; fermenting malted rice [Koji]; yeast; baking powder; instant bread mixes; instant confectionery mixes, namely, instant doughnut mixes, instant cake mixes, instant cookie mixes; sauce for pasta; by-product of rice for food [sake lees]; husked rice; husked oats; husked barley; wheat flours mixed with seasonings and spices; flour for food; fish, live; shellfish, live; algae for human and animal consumption; vegetables, fresh; fruits, fresh; foxtail millet, unprocessed; proso millet, unprocessed; sesame, unprocessed; buckwheat, unprocessed; corn, unprocessed grain; Japanese barnyard millet, unprocessed; wheat, barley and oats, unprocessed; unprocessed rice; sorghum, unprocessed; protein for animal consumption; animal foodstuffs, namely, pet food, pet food additives in the form of collagen peptide, animal food pellets; animal foodstuffs; livestock fattening preparations, namely, collagen peptide; beer; fruit juices; extracts of hops for making beer; whey beverages; vegetable juices, beverages; alcoholic fruit beverages. (1) Food processing; printing; collection, sorting and disposal of waste and trash; recycling of waste; computer software design, computer programming, and maintenance of computer software; rental of computers.
40 - Treatment of materials; recycling, air and water treatment,
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
29 - Meat, dairy products, prepared or preserved foods
31 - Agricultural products; live animals
32 - Beers; non-alcoholic beverages
33 - Alcoholic beverages other than beer
42 - Scientific, technological and industrial services, research and design
30 - Basic staples, tea, coffee, baked goods and confectionery
Goods & Services
[ Food processing; Rental of machines and apparatus for processing foods or beverages; Printing; Water treating; Recycling of waste; Treatment of cloth, clothing or fur, including treatment in the nature of drying ] [ Reagent kits consisting primarily of reagents for detecting toxic mold in foods; Reagent kits consisting primarily of reagents for detecting food allergens; Reagent kits consisting primarily of reagents for detecting source of food poisoning; Reagent kits consisting primarily of reagents for detecting toxin of food poisoning; Collagen for use in cosmetics; Collagen peptide for use in cosmetics; Chemical reagents and preparations for scientific purposes, other than for medical or veterinary use; Plant growth regulating preparations; Fertilizers; Artificial sweeteners; Food enriching preparations consisting mainly of collagen; collagen peptide for human consumption; collagen for human consumption; protein for human consumption, namely, proteins used in the manufacture of beverages, food products, and food supplements; Protein as raw materials used in the industrial preparation of animal feed for animal consumption; Animal foodstuffs, namely, collagen peptide as raw materials used in the industrial preparation of animal feed; Collagen peptide used as a raw material in livestock fattening preparations; Protein for animal consumption ] [ Anti-static preparations for household purposes; Degreasers for laundry use other than for use in manufacturing processes; Rust removing preparations; Stain removers; Fabric softeners for laundry use; Laundry bleach ] [ Sanitary preparations for medical use; Lacteal flour for babies; Foods for babies; Beverages for babies; Foods in the form of powders to add thickness consisting mainly of polysaccharide for the people with dysphagia; Collagen peptide for medical purposes, namely, used as an ingredient of regeneration medicine; Dietary supplements for humans; Lactobacillus-based dietary supplements for humans; Collagen-based dietary supplements for humans; Glucosamine-based dietary supplements for humans; Korean ginseng-based dietary supplements for humans; Elastin-based dietary supplements for humans; Placenta extract-based dietary supplements for humans; Dietary supplements for humans consisting mainly of borage oil, pork hydrolysate and safflower; Dietary supplements for humans consisting mainly of powdered chicken gristle; Chicken extract-based dietary supplements for humans; Dietary supplements for humans consisting mainly of carnosine and anserine; Dietary supplements for humans consisting mainly of edible aquatic animals and edible seaweeds; Dietary supplements for humans consisting mainly of amino acid, lecithin and herbs; Dietary supplements for humans consisting mainly of isomaltooligosaccharide and alimentary fiber; Propolis extract-based dietary supplements for humans; Royal jelly-based dietary supplements for humans; Semen for artificial insemination; Protein for human consumption as a dietary supplement ] [ Instruments and tools for food inspection and analysis, namely, instruments for measuring, testing, and control of physical, chemical and analytical properties, namely, for the measurement of the fat content analysis, the meat content analysis, the salt content analysis, the protein content analysis; Telecommunication machines and apparatus, namely, aeronautical radios, marine radio, single-channel radio, apparatus for transmission of communication; Protective helmets for sports; Downloadable image files featuring artwork, text, animation, still image, sports mascots, audio, video games and internet Web links relating to sporting and cultural activities; Recorded video discs and video tapes featuring artwork, text, animation, still image, sports mascots, audio, video games and internet Web links relating to sporting and cultural activities; Downloadable electronic publications, namely, books, magazines, manuals, recipes, newsletters, news reviews, directories, leaflets, pamphlets and catalogues, featuring artwork, text, animation, still image, sports mascots, audio, video games and internet Web links relating to sporting and cultural activities recorded on computer media; Research laboratory measuring or testing machines and instruments for measuring, testing and analyzing blood and other bodily fluids ] [ Pacifiers for babies; Ice bag pillows, for medical purposes; Triangular bandages; Supportive bandages; Surgical catguts; Feeding cups for medical purposes; Dropping pipettes for medical purposes; Teats; Ice bags for medical purposes; Medical ice bag holders; Baby bottles; Nursing bottles; Finger guards for medical purposes; Artificial tympanic membranes; Ear plugs for sleeping; Ear plugs for soundproofing; Massage apparatus; Gloves for medical purposes; Ear picks; Measuring or testing machines and instruments for measuring, testing and analyzing blood and other bodily fluids for medical purposes ] [ Milk products excluding ice cream, ice mill and frozen yogurt; ] Meat for human consumption, fresh, chilled or frozen; [ Fresh, chilled or frozen edible aquatic animals (not live); Frozen vegetables; Frozen fruits; Tonkatsu (Deep-fried breaded pork); Uncooked hamburger patties; Yakitori (Japanese style char-broiled chicken); ] Chinese-style barbecued pork; Seasoned beef [ and pork liver and plucks; ] Processed meat products; [ Processed seafood products; Coconut milk powder; Ham salad; Bean-starch vermicelli salad; Processed vegetables and fruits; Fried tofu pieces (Abura-age); Freeze-dried tofu pieces (Kohri-dofu); Jelly made from devils' tongue root (Konnyaku); Soya milk (milk substitute); Tofu consisting mainly of soya milk and collagen; Tofu; Fermented soybeans (Natto); Instant vegetable dish consisting primarily of shrimps, carrots, young corns and seasonings, also including and cooked with fresh broccoli; Instant vegetable dish consisting primarily of bacons, carrots, cheese and seasonings, also including and cooked with fresh asparagus; Instant vegetable dish consisting primarily of bacons, carrots and seasonings, also including and cooked with fresh potato; Instant vegetable dish consisting primarily of meats, processed meat products, edible aquatic animals and seasonings, also including and cooked with fresh vegetables; Hashed beef mixes; Instant miso soup; Prepared soup; Pre-cooked curry stew, stew and soup mixes; Ingredients for instant bowl of rice with a chop-suey-like mixture on it; Ingredients for instant Chinese dish of fried egg and crab; Ingredients for instant Chinese dish of tofu, vegetables and a spicy sauce (Tofu with vegetable in brown hot sauce); Ingredients for instant Chinese dish of eggplant and a spicy sauce; Ingredients for instant Chinese dish of bean vermicelli and a spicy sauce; Ingredients for instant Chinese dish of twice cooked pork (Szechuan dish); Ingredients for instant Chinese dish, called 'happosai'; Ingredients for instant Chinese dish of sweet and sour pork; Ingredients for instant Chinese dish of sweet and chili shrimp; Ingredients for instant Chinese dish of fried chopped chicken with cashew nuts; Ingredients for instant Chinese dish of Green pepper steak called "Chinjao Rosu"; Instant dish consisting mainly of cooked meats, vegetables, edible aquatic animals and seasonings; Dried flakes of laver for sprinkling on rice in hot water (Ochazuke-nori); Furi-kake (dried flakes of fish, meat, vegetables or seaweed); Side-dish made of fermented soybean (Name-mono); Formed textured vegetable protein for use as a meat substitute for human consumption; One-pot dish and/or barbecue consisting primarily of meats, edible aquatic animals and/or processed vegetables, and including assorted ingredients, namely, beef, pork, lamb, chicken, shellfish, fish, carrot, onion, green pepper, pumpkin, green onion, Chinese cabbage and cabbage; ] Fried chicken [ ; Prepared food consisting mainly of meat or processed meat products; Prepared food consisting mainly of edible aquatic animals; Prepared food consisting mainly of vegetables; Prepared food consisting mainly of fruits; Prepared food consisting mainly of Tofu; Processed algae for human consumption; Coconut-based beverage used as a milk substitute ] [ Fish, live, for food purposes; Shellfish, live; Unprocessed algae for human consumption; Vegetables, fresh; Fruits, fresh; Foxtail millet, unprocessed; Proso millet, unprocessed; Sesame, unprocessed; Buckwheat, unprocessed; Corn, unprocessed grain; Japanese barnyard millet, unprocessed; Wheat, barley and oats, unprocessed; Unprocessed rice; Sorghum, unprocessed; Animal foodstuffs including collagen peptide; Animal foodstuffs; Mash for fattening livestock; raw pulses ] [ Beer; Non-alcoholic beverages, namely, carbonated beverages and drinking water; Fruit juices; Extracts of hops for making beer; Whey beverages; Vegetable juices in the nature of beverages; Coconut milk, namely, coconut-based beverages not being milk substitutes ] [ Japanese liquors, in general; Western liquors, in general; Alcoholic fruit beverages; Chinese liquors, in general; Flavored liquors; Alcoholic beverages, except beer ] [ Designing of machines, apparatus, instruments, including their parts, or systems composed of such machines, apparatus and instruments; Graphic arts designing; Designing websites for others; Computer software design, programming, and maintenance of computer software; technical advice relating to performance and operation of computers; Testing, inspection or research of pharmaceuticals, cosmetics or foodstuff; Testing, inspection or research on agriculture, livestock breeding or fisheries; Rental of computers ] [ Starch-based binding agents for ice cream; Meat tenderizers for household purposes; Starch-based preparations for stiffening whipped cream; Aromatic preparations for flavoring food, other than from essential oils; Tea; Coffee-based beverage; Cocoa-based beverage; Ice; Breads with sausage in their center core; Bagels; Naan; Tortilla; Ciabatta; Chapati; English muffin; Scones; Croissant; Focaccia; Pita bread; Pain de champagne; Pain viennois; Brioche; Donuts; Curry breads; Sweets consisting mainly of coconut milk; Bread and buns; Seasonings for noodles; Sauce for steam vegetable dish; Sauce for tonkatsu (Sauce for deep-fried breaded pork); Seasonings other than spices; Spices; Ice cream mixes; Sherbet mixes; Unroasted coffee beans; Noodle-based prepared meals with their ingredients, broth or sauce; Noodle-based prepared meals; Bean-starch vermicelli with its ingredient for sautéed bean-starch vermicelli; Rice noodle with its ingredient for sautéed rice noodle; doughs; Almond paste; ] Chinese stuffed dumplings (Gyoza, cooked) [ ; Sandwiches; Chinese steamed dumplings (Shumai, cooked); Sushi; Fried balls of batter mix with small pieces of octopus (Takoyaki); Chinese-style steamed bun; Prepared hamburger sandwiches; Pizzas; Boxed lunches consisting primarily of rice, with added meat, fish or vegetables; Prepared hot dog sandwiches; Meat pies, prepared; Ravioli, prepared; Croque monsieur, prepared; Tartine, prepared; Wraps, prepared; Bagel with ham and cheese; English muffin with ham and cheese; Ciabatta with sauce and cheese; Tortilla with roast chickens; Naan with sausage; Breads with meats, edible aquatic animals, vegetables, cheese or the like; Shanghai-style steamed dumplings (Xiaolongbao); Steamed Chinese chives bun; Chinese rice cakes wrapped in bamboo leaves; Spring rolls; Yeast powder; Fermenting malted rice (Koji); Yeast; Baking powder; Instant bread mixes; Instant confectionery mixes; Sauce for pasta; By-product of rice for food (sake lees); Husked rice; Husked oats; Husked barley; Wheat flours mixed with seasonings and spices; Flour for food; Instant spicy sauce (mapo sauce) mixes for Sichuan style bean curd; Instant spicy sauce (mapo sauce) mixes for bean starch vermicelli; Broth noodles in the form of powder and liquid ]
HLA-E chimeric molecules for providing nonhuman mammalian cells resistant to cytotoxic human NK cells, nucleotide sequences encoding these chimeric molecules, and nonhuman mammalian cells and nonhuman mammals transformed with such nucleotide sequences are disclosed herein. The HLA-E chimeric molecules of the invention contain a peptide that reforms all or part of the signal peptide region, α1 domain and/or α2 domain of HLA-E, and a nucleotide sequence of the invention encodes a HLA-E chimeric molecule. A transformant incorporating a nucleotide sequence of the invention expresses HLA-E efficiently.
29 - Meat, dairy products, prepared or preserved foods
30 - Basic staples, tea, coffee, baked goods and confectionery
32 - Beers; non-alcoholic beverages
Goods & Services
Chicken breast extracts and other meat extracts; meat, fish, poultry and game; preserved, dried and cooked fruits and vegetables; jellies, jams, compotes; eggs, milk and milk products; edible oils and fats; dietary supplements containing chicken breast extracts in the form of capsules, tablets, drops, jellies, powders, liquids and bars. Coffee, tea, cocoa, sugar, rice, tapioca, sago, artificial coffee; flour and preparations made from cereals, bread, pastry and confectionery, ices; honey, treacle; yeast, baking-powder; salt, mustard; vinegar, sauces (condiments); spices; ice. Beers; mineral and aerated waters and other non-alcoholic drinks; fruit drinks and fruit juices; syrups and other preparations for making beverages.
