A support member (1) supports opposing members in a fuel battery (100) in which a plurality of fuel battery cells (50) are stacked. The support member (1) comprises a communication path (2). A gasket (10) has communication portions (16, 17) that allow through-holes (54a, 54b) and through-holes (51a, 51b) provided to the fuel cells (50) to communicate with a fuel gas flow path (71). The support member (1) extends to the communication portions (16, 17) of the gasket (10).
H01M 8/0276 - Sealing means characterised by their form
C25B 1/04 - Hydrogen or oxygen by electrolysis of water
C25B 9/00 - Cells or assemblies of cellsConstructional parts of cellsAssemblies of constructional parts, e.g. electrode-diaphragm assembliesProcess-related cell features
C25B 9/23 - Cells comprising dimensionally-stable non-movable electrodesAssemblies of constructional parts thereof with diaphragms comprising ion-exchange membranes in or on which electrode material is embedded
22m22nn-H (In the formula, R is a C3-5 alkenyl group having one double bond at a terminal thereof, and n is the average number of moles added and is 6-13.)
An object is to provide a lubricant oil composition excellent in biodegradability, lubricating property (extreme pressure property), stability against oxidation and demulsibility, having low toxicity and bioaccumulation property in an aquatic life, and excellent in stability against shearing even in the presence of water.
An object is to provide a lubricant oil composition excellent in biodegradability, lubricating property (extreme pressure property), stability against oxidation and demulsibility, having low toxicity and bioaccumulation property in an aquatic life, and excellent in stability against shearing even in the presence of water.
A lubricant oil composition comprises 100 mass parts of the following ester compound (A), 0.1 to 1.5 mass parts of the following amine salt (B) of an acidic phosphoric acid ester, 0.3 to 2.0 mass parts of an amine-based oxidation preventing agent (C), and 0.3 to 2.0 mass parts of a phenol-based oxidation preventing agent (D),
(A) the ester compound comprising a molar percentage of 20 to 30 mol % of a constituent component (a) derived from pentaerythritol, a molar percentage of 55 to 79 mol % of a constituent component (b) derived from a straight-chain fatty acid having a carbon number of 14 to 22, and a molar percentage of 1 to 15 mol % of a constituent component (c) derived from adipic acid, wherein a ratio [(c) mol %/(b) mol %] of the molar percentage of the constituent component (b) with respect to the molar percentage of the constituent component (c) is 0.02 to 0.25 and wherein the ester compound has a hydroxyl value of 10 to 100 mgKOH/g,
(B) the amine salt of an acidic phosphoric acid ester represented by the following formula (1),
An object is to provide a lubricant oil composition excellent in biodegradability, lubricating property (extreme pressure property), stability against oxidation and demulsibility, having low toxicity and bioaccumulation property in an aquatic life, and excellent in stability against shearing even in the presence of water.
A lubricant oil composition comprises 100 mass parts of the following ester compound (A), 0.1 to 1.5 mass parts of the following amine salt (B) of an acidic phosphoric acid ester, 0.3 to 2.0 mass parts of an amine-based oxidation preventing agent (C), and 0.3 to 2.0 mass parts of a phenol-based oxidation preventing agent (D),
(A) the ester compound comprising a molar percentage of 20 to 30 mol % of a constituent component (a) derived from pentaerythritol, a molar percentage of 55 to 79 mol % of a constituent component (b) derived from a straight-chain fatty acid having a carbon number of 14 to 22, and a molar percentage of 1 to 15 mol % of a constituent component (c) derived from adipic acid, wherein a ratio [(c) mol %/(b) mol %] of the molar percentage of the constituent component (b) with respect to the molar percentage of the constituent component (c) is 0.02 to 0.25 and wherein the ester compound has a hydroxyl value of 10 to 100 mgKOH/g,
(B) the amine salt of an acidic phosphoric acid ester represented by the following formula (1),
(in the formula (1), n represents an integer of 1 or 2, R′ represents a straight-chain alkyl group having a carbon number of 4 to 6, and R″ represents hydrogen or an alkyl group having a carbon number of 11 to 14.).
A connector includes a connector body having a tube insertion hole that is formed between a connector upper surface and a connector lower surface and into which a tube can be inserted and connected; a guide part that protrudes downward from the connector lower surface along a lower end peripheral edge of the connector body and is capable of being brought into contact with a part of a micro fluid device; and a lip part that surrounds a lower end opening of the tube insertion hole opened to the connector lower surface, protrudes downward from the connector lower surface, protrudes higher than the guide part, and is capable of being brought into contact with a part of the micro fluid device, wherein the connector body, the guide part, and the lip part are integrally formed by an elastically deformable elastic rubber material.
F16L 21/03 - Joints with sleeve or socket with elastic sealing rings between pipe and sleeve or between pipe and socket, e.g. with rolling or other prefabricated profiled rings placed in the socket before connection
B01L 3/00 - Containers or dishes for laboratory use, e.g. laboratory glasswareDroppers
A fluororubber composition in which fluororubber is compounded with triiron tetraoxide having a BET specific surface area of 4.0 m2/g or less at a ratio of 7.0 vol % or more as a volume fraction. A crosslinked product obtained by the fluororubber composition according to the present invention can be detected 1 mm pieces thereof by using a metal detector ND-840, produced by Nissin Electronics Co., Ltd., under the detection sensitivity conditions (Fe: 0.6 in diameter, SUS: 1.5 in diameter). Further, the compression set of the crosslinked product using an O-ring at 175° C. after 70 hours is 21% or less, and thus the crosslinked product can be effectively used for gaskets, O-rings, and the like for food production facilities, food machinery, automobiles, etc.
A rubber composition that includes (A) a polymer, (B) a crosslinking agent, and (C) a colorant, wherein the colorant (C) does not contain an inorganic black pigment, and a minimum transmittance in a wavelength of 800 to 1600 nm is 50% or more and a maximum transmittance in a wavelength of 350 to 700 nm is 40% or less in a rubber sheet having a thickness of 2 mm.
Provided is a soft contact lens comprising: a hydrogel; a first coating layer which has an oxazoline group, or a first coating layer having an oxazoline group and a fatty acid covalently bonded to the oxazoline group; and a second coating layer which has a carboxyl group or a phenolic hydroxyl group. Thus, provided is a soft contact lens which has two coating layers formed on a surface thereof, and in which said surface exhibits sufficient hydrophilicity and lubricity event when the soft contact lens is worn continuously for a long period.
G02B 1/04 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements made of organic materials, e.g. plastics
B29D 11/00 - Producing optical elements, e.g. lenses or prisms
C08L 33/10 - Homopolymers or copolymers of methacrylic acid esters
C08L 39/04 - Homopolymers or copolymers of monomers containing heterocyclic rings having nitrogen as ring member
C08L 43/02 - Homopolymers or copolymers of monomers containing phosphorus
This pasty body cleanser composition comprises: 0.1-6 mass% of an isoparaffin having an average carbon number of 50-250 as a component (A); 0.2-14 mass% of an isoparaffin having an average carbon number of 20-24 as a component (B); 10-50 mass% of a fatty acid salt having 8-22 carbon atoms as a component (C); 5-30 mass% of a polyhydric alcohol having 2-4 carbon atoms and a valence of 2-3 as a component (D); and water, wherein the mass ratio ((A)/(B)) of the component (A) to the component (B) is 1/20 to 3/2.
a22bn2ncc}-H, wherein the symbols are as defined in the description; a cosmetic vehicle comprising the polyether polyol; and a cosmetic comprising the vehicle. The polyether polyol according to the present invention is excellent in compatibility with water and compatibility with a hydrocarbon oil. The cosmetic according to the present invention is excellent in moisturizing effect, lack of stickiness, fixation of makeup under high humidity conditions, and makeup fixation under low humidity conditions.
C08G 65/34 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
A battery buffering material which prevents a reaction force from increasing suddenly even when the compression ratio is large, and maintains its heat insulating performance is provided. A battery buffering material 100 is a buffering material disposed between adjacent members which constitute a battery, includes a sheet-like structure made of an elastic material, and front surface protruding portions 21 extending on the side of a front surface 11 thereof and the back surface protruding portions 22 extending on the side of a back surface 13 thereof, wherein the front surface protruding portions and the back surface protruding portions have a hollow conical shape or a hollow spherical segment shape, and the front surface protruding portions 21 and the back surface protruding portions 22 collapse when an external force due to expansion of the members is applied to the battery buffering material.
H01M 50/242 - MountingsSecondary casings or framesRacks, modules or packsSuspension devicesShock absorbersTransport or carrying devicesHolders characterised by physical properties of casings or racks, e.g. dimensions adapted for protecting batteries against vibrations, collision impact or swelling
H01M 50/204 - Racks, modules or packs for multiple batteries or multiple cells
H01M 50/291 - MountingsSecondary casings or framesRacks, modules or packsSuspension devicesShock absorbersTransport or carrying devicesHolders characterised by spacing elements or positioning means within frames, racks or packs characterised by their shape
H01M 50/293 - MountingsSecondary casings or framesRacks, modules or packsSuspension devicesShock absorbersTransport or carrying devicesHolders characterised by spacing elements or positioning means within frames, racks or packs characterised by the material
The invention relates to an oil agent for cosmetics, containing 70%-99% by mass of (A) a primary alcohol having a branched chain and 20-30 carbon atoms, and 1%-30% by mass of (B) a primary alcohol having a branched chain and 12-19 carbon atoms, an emulsion cosmetic containing the oil agent for cosmetics, (C) a divalent to hexavalent polyhydric alcohol having 3-6 carbon atoms, and (D) a non-ionic surfactant having an HLB value of 10-18, at a given content ratio, and a cosmetic containing component (A) and component (B), and (F) an inorganic powder having an average particle size of 10 nm to 100 μm, at predefined contents. An emulsion cosmetic that is superior in a feeling of thickness penetration into the skin and a cosmetic that can suppress a feeling of dryness and a sense of friction due to the inclusion of inorganic powder can be provided.
Provided is a soft contact lens including a hydrogel having a glycidyl group, a first coating layer having a carboxyl group and/or an amino group, and a second coating layer having a glycidyl group, in which two coating layers are formed on a surface, and the surface has sufficient hydrophilicity and lubricity even in a case where the soft contact lens is worn continuously for a long period of time.
G02B 1/04 - Optical elements characterised by the material of which they are madeOptical coatings for optical elements made of organic materials, e.g. plastics
G02B 1/18 - Coatings for keeping optical surfaces clean, e.g. hydrophobic or photo-catalytic films
A plurality of microfluidic chips are prepared in which a main chip having a minute space into which a liquid is introduced is held in a guide. These microfluidic chips are connected in a row, and the minute spaces provided in two adjacent main chips are connected by a joint chip. The joint chip is held half each by the respective guides so as to straddle the two adjacent main chips to form a portion of a flow channel including the minute spaces provided in the two main chips. The minute spaces included in the two adjacent main chips and a communication flow path built into the joint chip are connected by a main communication hole of the main chip and a joint communication hole of the joint chip to form a flow channel.
This thermally conductive rubber composition contains a base rubber, a thermally conductive filler, and an aliphatic amine compound, and has a durometer hardness (type A) of 80 or less, a thermal conductivity of 3.0 W/mK or more, and an elongation at break of 300% or more.
This resin composition for a sealing material comprises (A) a polyfunctional thiol having 2-6 thiol groups, (B) a compound having 2-3 polymerizable unsaturated bonds, and (C) a crosslinking regulator. The (B) compound having 2-3 polymerizable unsaturated bonds contains (B1) a bifunctional urethane (meth)acrylate. The (C) crosslinking regulator is an amine compound that is solid at 25°C. The resin composition for a sealing material has high viscosity stability in an uncured state, and has, after being cured, high adhesion to a base material, cleaning liquid resistance, excellent light resistance, and the ability to suppress bleed-out under high temperature and high humidity conditions.
A nucleic acid amplification promoter according to the present invention comprises a copolymer containing a constituent unit derived from a monomer represented by formula (1) and a constituent unit derived from a monomer represented by formula (2). The present invention can provide a nucleic acid amplification promoter capable of promoting nucleic acid amplification and improving detection sensitivity when added to a nucleic acid amplification composition. (X1represents a (meth)acryloyloxy group or a (meth)acryloyl amide group; L1represents an alkylene group having 2 to 4 carbon atoms and optionally having one hydroxy group, or an alkylene oxyalkylene group having 2 to 4 carbon atoms; and R1to R3each independently represent an alkyl group having 1 to 3 carbon atoms. R4represents a hydrogen atom or a methyl group, and R5 is a group having any one of a sulfo group, a phosphate group, a sulfate group, and a phosphonic acid group.)
C12Q 1/6848 - Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
C08F 230/02 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing phosphorus
17.
CURING AGENT, THERMOSETTING COMPOSITION, RESIN FILM, PREPREG, METAL-CLAD LAMINATED PLATE, AND METHOD FOR PRODUCING CURING AGENT
This curing agent contains an organic peroxide and is solid at 25°C, wherein: (i) the dielectric loss tangent measured with a capacitance method by dissolving the curing agent in a cable oil to achieve a concentration of 10% by mass is 0.0015 or less; (ii) the purity of the organic peroxide analyzed by liquid chromatography is 99.5% or more; and the organic peroxide is one or more selected from the group consisting of a compound represented by general formula (1), a compound represented by general formula (2), and a compound represented by general formula (3). The curing agent provides a thermosetting resin having excellent dielectric properties, heat resistance, and adhesiveness to metal.
B32B 15/08 - Layered products essentially comprising metal comprising metal as the main or only constituent of a layer, next to another layer of a specific substance of synthetic resin
C07C 409/16 - Peroxy compounds the —O—O— group being bound between two carbon atoms not further substituted by oxygen atoms, i.e. peroxides
C07F 7/08 - Compounds having one or more C—Si linkages
The present invention provides a polyether represented by formula (1) (the symbols of which are defined in the description). This polyether is suited to various applications, including a cosmetic base.
C08G 65/34 - Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from hydroxy compounds or their metallic derivatives
This thermal degradation determination method involves determining thermal degradation of a rubber composition. The thermal degradation determination method includes a thermal degradation determination process for determining whether the thermal degradation of the rubber composition exceeds a predetermined level of thermal degradation. The thermal degradation determination process involves comparing the weight ratio of a carbon precursor in the rubber composition with a set threshold value to determine whether the thermal degradation of the rubber composition exceeds the predetermined level of thermal degradation.
G01N 5/04 - Analysing materials by weighing, e.g. weighing small particles separated from a gas or liquid by removing a component, e.g. by evaporation, and weighing the remainder
G01N 17/00 - Investigating resistance of materials to the weather, to corrosion or to light
G01N 25/20 - Investigating or analysing materials by the use of thermal means by investigating the development of heat, i.e. calorimetry, e.g. by measuring specific heat, by measuring thermal conductivity
abcc = 5-50, and Mw of the polymer being 10,000-2,000,000. (R133, X is O or NR2, R2is H or a C1-4 alkyl group, and n = 1-4). (R333, Y is O or NR4, R4is H or a C1-4 alkyl group, and m is 1-6; there may be one or more hydroxyl groups in the carbon chain; A is a phosphorylcholine group or a hydroxyl group, and may be H if m = 1 or if there is a hydroxyl group in the carbon chain). (R533, and R6is an alkylene group forming a cyclic structure together with R5or a C1-4 alkyl group). (R733, Z is O or NR9, R 9is H or a C1-4 alkyl group, and R8 is a C1-10 alkyl group).
C08F 220/60 - Amides containing nitrogen in addition to the carbonamido nitrogen
21.
HIGH-PURITY 2-AMINOETHYL METHACRYLATE HYDROCHLORIDE, COPOLYMER INCLUDING SAID HYDROCHLORIDE AS STRUCTURAL UNIT, AND METHOD FOR PRODUCING 2-AMINOETHYL METHACRYLATE HYDROCHLORIDE
This method for producing 2-aminoethyl methacrylate hydrochloride comprises a reaction step for reacting aminoethanol hydrochloride and methacrylic acid chloride and a drying step for drying 2-aminoethyl methacrylate hydrochloride obtained in the reaction step at not higher than 45°C.
C07C 213/06 - Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton from hydroxy amines by reactions involving the etherification or esterification of hydroxy groups
C07C 213/10 - SeparationPurificationStabilisationUse of additives
C07C 219/08 - Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the hydroxy groups esterified by a carboxylic acid having the esterifying carboxyl group bound to an acyclic carbon atom of an acyclic unsaturated carbon skeleton
C08F 230/02 - Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and containing phosphorus, selenium, tellurium or a metal containing phosphorus
A cleaning blade according to the present invention is a plate-like member including a tip part, and comprises: a first surface adhered to a support member; a second surface on the side opposite of the first surface; a third surface connecting the first surface and the second surface; and a fourth surface connecting the first surface and the second surface on the side opposite of the third surface. The tip part is a portion where the second surface and the third surface intersect, and a first angle formed by the first surface and the fourth surface is an obtuse angle.
This cleaning device is provided with a plate-shaped cleaning blade that includes a tip section that makes contact with an object, and a support member that supports the cleaning blade, wherein a displacement amount, which is the distance between the position of the tip section in a state in which the rotation of the object is stopped and the position of the tip section in a state in which the object is rotating, is 32 μm or less.
G03G 21/00 - Arrangements not provided for by groups , e.g. cleaning, elimination of residual charge
G03G 15/16 - Apparatus for electrographic processes using a charge pattern for transferring a pattern to a second base of a toner pattern, e.g. a powder pattern
A cell unit (2) comprises: a base material (10) that defines a first surface (11) and a second surface (12) facing each other; a hole (13) that penetrates from the first surface (11) to the second surface (12); a film (21) that is disposed in the hole (13) and partitions the hole (13) into a first space (15) on the first surface (11) side and a second space (16) on the second surface (12) side; a first flow path (40) that is formed on the base material (10) and serves for introducing a first fluid into the first space (15); a second flow path (42) that is formed on the base material (10) and serves for taking out a second fluid from the second space (16); a first gasket (50) disposed on the first surface (11) and surrounding the first space (15) and the first flow path (40); and a second gasket (51) disposed on the first surface (11) and surrounding the second flow path (42) on the outside of the first gasket (50).
C25B 9/00 - Cells or assemblies of cellsConstructional parts of cellsAssemblies of constructional parts, e.g. electrode-diaphragm assembliesProcess-related cell features
C25B 1/04 - Hydrogen or oxygen by electrolysis of water
An acetal-type releasable polyoxyethylene derivative is expressed by the Formula (1), (2), (3) or (4) as defined herein, and cleaved under a physiological condition, and in the formulas (1), (2), (3) and (4), B1 represents a hydrogen atom or —C(R1)(R2)OC(O)E1, E1 represents a leaving group, P1 represents a polyoxyethylene derivative having a dehydroxylated group, w represents an integer of 1 to 8, R1, R2, R3, R4, R5 and R11 each independently represent a hydrocarbon group having 1 to 10 carbon atoms or a hydrogen atom, R6, R7, R8, R9 and R10 each independently represent an electron-withdrawing substituent, an electron-donating substituent, or a hydrogen atom, and m represents 0 or 1.
A61K 47/60 - Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additivesTargeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
C08G 65/331 - Polymers modified by chemical after-treatment with organic compounds containing oxygen
C08G 65/333 - Polymers modified by chemical after-treatment with organic compounds containing nitrogen
C08G 65/337 - Polymers modified by chemical after-treatment with organic compounds containing other elements
26.
HUMIDIFYING MEMBRANE MODULE FOR FUEL CELL, HOLLOW FIBER MEMBRANE FOR HUMIDIFYING FUEL CELL, METHOD FOR PRODUCING HOLLOW FIBER MEMBRANE FOR HUMIDIFYING FUEL CELL, AND METHOD FOR HUMIDIFYING FUEL CELL
The present invention provides, for example, a humidifying membrane module for a fuel cell, comprising a hollow fiber membrane which has excellent durability. Provided are, for example: a hollow fiber membrane (40) for humidifying a fuel cell, comprising a cylindrical braid (41) and a porous membrane (42) that is provided to the outer peripheral side of the braid (41); a humidifying membrane module (1) for a fuel cell, comprising the hollow fiber membrane (40); and a method for humidifying a fuel cell using the hollow fiber membrane (40).
B01D 53/22 - Separation of gases or vapoursRecovering vapours of volatile solvents from gasesChemical or biological purification of waste gases, e.g. engine exhaust gases, smoke, fumes, flue gases or aerosols by diffusion
D01F 6/76 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from homopolycondensation products from other polycondensation products
D01F 6/94 - Monocomponent man-made filaments or the like of synthetic polymersManufacture thereof from mixtures of polycondensation products as major constituent with other polymers or low-molecular-weight compounds of other polycondensation products
A gasket (1) is a gasket that is compressed to seal the space between a pair of opposing members. The gasket (1) is provided with an annular adhesive portion (10) and an annular seal portion (20). The seal portion (20) prevents the adhesive portion (10) from being exposed to the sealed space.
This curing agent for a low dielectric resin (A) comprises (a1) an organic peroxide represented by general formula (1) and (a2) an organic peroxide represented by general formula (2). The proportion of the (a1) organic peroxide with respect to the total of the (a1) organic peroxide and the (a2) organic peroxide is 5-95 mass%. The curing agent for a low dielectric resin is capable of achieving both low dielectric properties and heat resistance.
This cell unit (2) comprises: a base material (10) that defines a first surface (13) and a second surface (14) that face each other back to back; a hole (15) that penetrates the base material (10) from the first surface (13) to the second surface (14); a film (21) that is disposed in the hole (15) and partitions the hole (15) into a first space (17) on the first surface (13) side and a second space (18) on the second surface (14) side; and an annular outer peripheral member (32) disposed around the outer peripheral surface (11a) of the base material (10).
C25B 9/00 - Cells or assemblies of cellsConstructional parts of cellsAssemblies of constructional parts, e.g. electrode-diaphragm assembliesProcess-related cell features
C25B 1/04 - Hydrogen or oxygen by electrolysis of water
The present invention provides a sensitizer for immunochromatographic assay capable of detecting novel coronavirus (SARS-CoV-2) IgM antibodies and/or IgG antibodies with high sensitivity, and an assay using the sensitizer. Specifically, the present invention provides a sensitizer for immunochromatographic assay for novel coronavirus (SARS-CoV-2) IgM antibodies and/or IgG antibodies as assay target substances, that contains a polymer represented by the following formula [4]:
The present invention provides a sensitizer for immunochromatographic assay capable of detecting novel coronavirus (SARS-CoV-2) IgM antibodies and/or IgG antibodies with high sensitivity, and an assay using the sensitizer. Specifically, the present invention provides a sensitizer for immunochromatographic assay for novel coronavirus (SARS-CoV-2) IgM antibodies and/or IgG antibodies as assay target substances, that contains a polymer represented by the following formula [4]:
The present invention provides a sensitizer for immunochromatographic assay capable of detecting novel coronavirus (SARS-CoV-2) IgM antibodies and/or IgG antibodies with high sensitivity, and an assay using the sensitizer. Specifically, the present invention provides a sensitizer for immunochromatographic assay for novel coronavirus (SARS-CoV-2) IgM antibodies and/or IgG antibodies as assay target substances, that contains a polymer represented by the following formula [4]:
wherein m, n, and p are each a constitutional unit number, an m:n:p is 100 to 30:0 to 70:0 to 50.
This anti-fogging agent composition contains a copolymer (A), a polyfunctional block isocyanate compound (B), a surfactant (C), and a solvent (D), wherein the solvent (D) contains a dihydric alcohol (D-1) and a glycol ether (D-2) with the content of (D-1) being 5-35 parts by mass and the content of (D-2) being 3-15 parts by mass with respect to 100 parts by mass of the anti-fogging agent composition, and the mass ratio [(D-1)/(D-2) ] of (D-1) to (D-2) being 0.5-8.0. This anti-fogging agent composition provides an anti-fogging film formed by heat curing that excels in appearance, adhesion, anti-fogging performance, and water streaking marks, and can suppress dripping or brush marks during coating, and can suppress solvent cracking when performing heat curing at a high temperature.
This dust cover includes an elastic body having an annular first end section. The first end section includes: an annular end surface; an annular first protrusion that protrudes from the end surface; and an annular second protrusion that protrudes from the end surface more on the radial-direction outer side of the end surface than the first protrusion. In plan view, the apex of the first protrusion is closer to the outer circumferential edge than to the inner circumferential edge of the first protrusion.
F16J 15/52 - Sealings between relatively-movable members, by means of a sealing without relatively-moving surfaces, e.g. fluid-tight sealings for transmitting motion through a wall by means of sealing bellows or diaphragms
122: aluminum, R: an alkyl group having 1-8 carbon atoms, R': a methyl group, an OR group, n: an integer of 1-3, m: 1 or 2) or (1b) a mixture of the organic metal compound and a metal alkoxide compound, and (2) a silane-based adhesive layer, which is a top coating layer as well as a surface treatment agent layer containing silica having a solid content ratio of 90:10 to 50:50 by weight and not containing a silane coupling agent or an oligomer thereof, and an EPDM layer, which is a rubber layer, or a phenolic resin-based adhesive layer, which is a top coating layer, and a fluororubber layer, a nitrile rubber layer, or a hydrogenated nitrile rubber layer, which are rubber layers.
C09J 5/02 - Adhesive processes in generalAdhesive processes not provided for elsewhere, e.g. relating to primers involving pretreatment of the surfaces to be joined
C09J 127/18 - Homopolymers or copolymers of tetrafluoroethene
C09J 129/14 - Homopolymers or copolymers of acetals or ketals obtained by polymerisation of unsaturated acetals or ketals or by after-treatment of polymers of unsaturated alcohols
Provided is a sealing device which has high sound insulation and which applies less torque to a rotary shaft. The sealing device seals a gap between an outer support member and the rotary shaft, which is disposed in a hole provided in the outer support member. The sealing device includes: an attachment part that is attached to the outer support member; a cylindrical part that is disposed inside the attachment part; a sliding part that is disposed inside the cylindrical part and that slidably contacts an outer peripheral surface of the rotary shaft; and an elastomer bellows part interposed between the attachment part and the cylindrical part. The bellows part includes: an outer inclined part having a truncated cone shape; an inner inclined part having a truncated cone shape inclined in the opposite direction to the outer inclined part; and a bent part connecting the outer inclined part and the inner inclined part. The outer inclined part includes an outer thick part thicker than the bent part. The inner inclined part includes an inner thick part thicker than the bent part.
F16J 15/3224 - Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings with at least one lip capable of accommodating changes in distances or misalignment between the surfaces, e.g. able to compensate for defaults of eccentricity or angular deviations
F16J 15/52 - Sealings between relatively-movable members, by means of a sealing without relatively-moving surfaces, e.g. fluid-tight sealings for transmitting motion through a wall by means of sealing bellows or diaphragms
B62D 1/20 - Connecting steering column to steering gear
A battery-cushioning member disposed between a first rigid body and a second rigid body includes a sheet-shaped heat insulation member with a first surface and a second surface facing in a direction opposite to that of the first surface. At least one first elastic body is disposed on the first surface and formed integrally with the heat insulation member. The at least one first elastic body creates a partial space between the first surface and the first rigid body. Preferably, the battery-cushioning member further includes at least one second elastic body disposed on the second surface and formed integrally with the heat insulation member. The at least one second elastic body creates a partial space between the second surface and the second rigid body.
H01M 50/291 - MountingsSecondary casings or framesRacks, modules or packsSuspension devicesShock absorbersTransport or carrying devicesHolders characterised by spacing elements or positioning means within frames, racks or packs characterised by their shape
H01M 10/658 - Means for temperature control structurally associated with the cells by thermal insulation or shielding
H01M 50/204 - Racks, modules or packs for multiple batteries or multiple cells
H01M 50/242 - MountingsSecondary casings or framesRacks, modules or packsSuspension devicesShock absorbersTransport or carrying devicesHolders characterised by physical properties of casings or racks, e.g. dimensions adapted for protecting batteries against vibrations, collision impact or swelling
H01M 50/293 - MountingsSecondary casings or framesRacks, modules or packsSuspension devicesShock absorbersTransport or carrying devicesHolders characterised by spacing elements or positioning means within frames, racks or packs characterised by the material
A sealing device is configured to be provided between a first member including a first surface provided with a first space and a second member including a second surface provided with a second space having a diameter greater than a diameter of the first space, the second space facing the first surface. The sealing device includes a tubular elastic body that includes a first outer-circumferential surface facing an inner-circumferential surface defining the first space; a second outer-circumferential surface, which has a diameter greater than a diameter of the first outer-circumferential surface, facing an inner-circumferential surface defining the second space, a step surface defining a difference in level between the first outer-circumferential surface and the second outer-circumferential surface and being in contact with the first surface; an annular first protrusion protruding from the first outer-circumferential surface; and an annular second protrusion protruding from the second outer-circumferential surface.
This sealing device comprises a reinforcement ring along an inner circumferential surface of a hole of a housing, and a cylindrical seal member fixed to the reinforcement ring and composed of an elastic material. The seal member includes: a first sealing part which is in close contact with the inner circumferential surface of the hole in a state of being elastically deformed by compression between the inner circumferential surface of the hole and the reinforcement ring; a second sealing part which is in close contact with an inner circumferential surface of a flow path member in a state of being elastically deformed by compression between an inner circumferential surface of one member among the flow path member and piping and the reinforcement ring; and a lip part that protrudes towards the inner side in the radial direction and contacts the outer circumferential surface of the other member among the flow path member and the piping. The lip part comes into contact with the outer circumferential surface of the other member in a state of extending in a direction inclined with respect to the radial direction so as to approach the inner side of the one member toward the inner side in the radial direction without using a band for pressing the outer circumferential surface of the seal member in the direction towards the other member.
The present invention provides a polyolefin having a number average molecular weight of 250 to 10,000 and obtained from a linear olefin monomer having 8 to 20 carbon atoms, wherein a rate of side chains having (n−3) carbon atoms or 5 lower than (n−3) carbon atoms is 1 to 40%, as calculated from the formula (1):
The present invention provides a polyolefin having a number average molecular weight of 250 to 10,000 and obtained from a linear olefin monomer having 8 to 20 carbon atoms, wherein a rate of side chains having (n−3) carbon atoms or 5 lower than (n−3) carbon atoms is 1 to 40%, as calculated from the formula (1):
rate
of
side
chains
having
(
n
-
3
)
carbon
atoms
or
lower
than
(
n
-
3
)
carbon
atoms
(
%
)
=
[
Nx
/
(
Nx
+
Ny
)
×
2
n
-
3
]
/
3
×
100
[
symbols
in
the
formula
(
1
)
are
as
defined
in
the
DESCRIPTION
]
.
C08F 10/14 - Monomers containing five or more carbon atoms
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
Provided is a biodegradable lubricating oil composition which is excellent in terms of biodegradability, lubricity (extreme pressure property), demulsibility, and friction-reducing property and is highly effective in friction reduction even in the presence of seawater. The biodegradable lubricating oil composition is characterized by comprising 100 parts by mass of a specific ester compound (A), 0.1-10.0 parts by mass of a specific poly(alkyl (meth)acrylate) (B), and 0.1-1.5 parts by mass of a specific acidic phosphoric acid ester amine salt (C).
C10M 169/04 - Mixtures of base-materials and additives
C10M 105/42 - Complex esters, i.e. compounds containing at least three esterified carboxyl groups and derived from the combination of at least three different types of the following five types of compound: monohydroxy compounds, polyhydroxy compounds, monocarboxylic acids, polycarboxylic acids and hydroxy carboxylic acids
C10N 30/00 - Specified physical or chemical property which is improved by the additive characterising the lubricating composition, e.g. multifunctional additives
C10N 30/06 - OilinessFilm-strengthAnti-wearResistance to extreme pressure
A dust cover according to the present invention is to be fixed to a socket that supports a ball stud. The dust cover comprises a body part that surrounds the ball stud and an annular fixed part that is connected to the body part. The fixed part includes an inner circumferential surface that contacts an installation groove in the socket, an outer circumferential surface that is on the reverse side from the inner circumferential surface, an annular groove part that is formed at the outer circumferential surface and accommodates a fastening member that fastens the fixed part to the socket, and an extending outer surface that connects the outer circumferential surface and an outer surface of the body part. At a first bent part that is positioned further to the outside in the radial direction of the fixed part than a first virtual surface that is a continuous extension of the outer surface of the body part toward the groove part, the outer circumferential surface of the fixed part is bent relative to the extending outer surface and is positioned further to the outside in the radial direction than an outer circumferential part of the fastening member.
F16J 15/52 - Sealings between relatively-movable members, by means of a sealing without relatively-moving surfaces, e.g. fluid-tight sealings for transmitting motion through a wall by means of sealing bellows or diaphragms
A pressure regulation valve (1) comprises: a housing (10) that has a plurality of through holes (11); and a valve body (20) that opens and closes each of the plurality of through holes (11). The housing (10) has a plurality of annular protrusions (30) that respectively surround openings (11a) of the plurality of through holes (11). The protrusions (30) protrude from the opening (11a) side and have a peak (31). The valve body (20) has a contact surface (21) that contacts the protrusions (30). The contact surface (21) of the valve body (20) contacts the protrusions (30) at annular contact regions (S) that have a width in the radial direction. The contact regions (S) of the contact surface (21) include a peak region (S1) that contacts the peak (31), an inside region (S2) that contacts the portion on the inner circumferential side of the peak (31), and an outside region (S3) that contacts the portion on the outer circumferential side of the peak (31). The protrusions (30) are shaped such that the width (w1) in the radial direction of the outside region (S3) is greater than the width (w2) in the radial direction of the inside region (S2).
A sealing device 1 includes a reinforcing ring 10 and an elastic body piece 20. A lip distal end portion 22 of a seal lip 21 of the elastic body piece 20 has a sealed-side surface 24 and an atmosphere-side surface 23 connected to each other with a lip edge 22a in between. The atmosphere-side surface 23 is provided with a plurality of projecting structures 2 arranged side by side in a circumferential direction. The projecting structures 2 each include a first projection 31 and a second projection 32 adjacent in the circumferential direction. The first projection 31 is a projection for returning a sealed object leaking during a rotation of a rotary shaft in a normal rotation direction to a sealed-object side by a pumping action. The second projection 32 is a projection for returning the sealed object leaking during a rotation of the rotary shaft in a reverse rotation direction to the sealed-object side by the pumping action.
F16J 15/3244 - Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings with hydrodynamic pumping action
F16J 15/3212 - Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings with at least one lip provided with tension elements, e.g. elastic rings with metal springs
F16J 15/3232 - Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings with at least one lip having two or more lips
F16J 15/3284 - Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings characterised by their structureSelection of materials
This charge roller includes a core material, a base material having a thickness L1 and covering the outer circumferential surface of the core material, and a surface layer having a thickness L2 and covering the outer circumferential surface of the base material. The outer peripheral surface of the surface layer is in contact with a facing member and has a contact area S, and the power difference ΔW between the power W1 of the base material and the power W2 of the surface layer is (3.4 × L2-0.004 × L1)/S [mW] or less.
G03G 15/02 - Apparatus for electrographic processes using a charge pattern for laying down a uniform charge, e.g. for sensitisingCorona discharge devices
44.
SEPARATOR INTEGRATED GASKET AND STACKED STRUCTURE INCLUDING THE SAME
Provided is a separator integrated gasket capable of stably performing a sealing function. A separator integrated gasket includes a first separator component 110 and a second separator component 120 joined to the first separator component 110 in a superposed manner, the first separator component 110 has a first elastic member 140 provided in a planar region of the first separator component 110, and the second separator component 120 has a main bead portion 122 and a second elastic member 150 fixed along the top of the main bead portion 122.
A torsional damper having reduced radiated noise from a hub is provided. The torsional damper has a value of a spring ratio relative to a resonance frequency ratio of a hub and a ring of 0.9 or more.
An electrolyte sealing material that is an ethylene/propylene-based copolymer rubber composition obtained by compounding PTFE and/or titanium dioxide in ethylene/propylene-based copolymer rubber, wherein the amount of PTFE and/or titanium dioxide compounded in the total amount of fillers is 10 wt. % or more. The electrolyte sealing material has high gas shielding properties, excellent electrical insulation properties, and resistance to electrolytes, and that compounds in rubber are not extracted by the electrolyte, that can be suitably used as a sealing material for various batteries such as lithium ion batteries and nickel metal hydride batteries, electrolytic capacitors, electric double layer capacitors, and the like.
A polymer for a water repellent, comprises a homopolymer comprising structural units derived from a monomer (a) represented by formula (1) or a copolymer comprising the structural units derived from the monomer (a) and structural units derived from a vinyl monomer (b) copolymerizable with the monomer (a). A mass ratio ((a)/(b)) of a mass of the monomer (a) with respect to a mass of the monomer (b) is 100/0 to 30/70.
A polymer for a water repellent, comprises a homopolymer comprising structural units derived from a monomer (a) represented by formula (1) or a copolymer comprising the structural units derived from the monomer (a) and structural units derived from a vinyl monomer (b) copolymerizable with the monomer (a). A mass ratio ((a)/(b)) of a mass of the monomer (a) with respect to a mass of the monomer (b) is 100/0 to 30/70.
A polymer for a water repellent, comprises a homopolymer comprising structural units derived from a monomer (a) represented by formula (1) or a copolymer comprising the structural units derived from the monomer (a) and structural units derived from a vinyl monomer (b) copolymerizable with the monomer (a). A mass ratio ((a)/(b)) of a mass of the monomer (a) with respect to a mass of the monomer (b) is 100/0 to 30/70.
R1 represents a hydrogen atom, a methyl group, chlorine, bromine or iodine, R2 represents an alkyl group having a carbon number of 12 to 24, A represents an alkylene group having a carbon number of 1 to 10, X represents 0 or 1, Y represents a structure selected from the group consisting of hydroxy urethane structures represented by formula (2), formula (3), formula (4) and formula (5) disclosed herein.
C09K 3/18 - Materials not provided for elsewhere for application to surface to minimize adherence of ice, mist or water theretoThawing or antifreeze materials for application to surfaces
C09D 133/26 - Homopolymers or copolymers of acrylamide or methacrylamide
D06M 15/263 - Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds of unsaturated carboxylic acidsSalts or esters thereof
The present invention is a lubricating oil composition containing, per 100 parts by mass of (A) an ester compound of a neopentyl polyol having 5 to 10 carbon atoms and a valence of alcohol of 2 to 6 and a linear unsaturated fatty acid having 16 to 22 carbon atoms, 0.1 to 1.5 parts by mass of a specific (B) acid phosphate ester amine salt, 0.01 to 0.25 parts by mass of a specific (C) succinic acid monoester, and 0.01 to 0.25 parts by mass of (D)N-oleoylsarcosine. According to the present invention, it is possible to provide a lubricating oil composition which is excellent in biodegradability, lubricity (anti-wear property), and rust preventive property against seawater, which is low in toxicity and accumulation to aquatic organisms, and further which is excellent in oxidation stability even in the presence of seawater.
C10M 169/00 - Lubricating compositions characterised by containing as components a mixture of at least two types of ingredient selected from base-materials, thickeners or additives, covered by the preceding groups, each of these compounds being essential
C10M 141/10 - Lubricating compositions characterised by the additive being a mixture of two or more compounds covered by more than one of the main groups , each of these compounds being essential at least one of them being an organic phosphorus-containing compound
C10M 169/04 - Mixtures of base-materials and additives
C10N 30/00 - Specified physical or chemical property which is improved by the additive characterising the lubricating composition, e.g. multifunctional additives
C10N 30/06 - OilinessFilm-strengthAnti-wearResistance to extreme pressure
C10N 30/10 - Inhibition of oxidation, e.g. anti-oxidants
C10N 30/12 - Inhibition of corrosion, e.g. anti-rust agents, anti-corrosives
The disclosure provides a ball joint seal structure that includes a ferrule ring interposed between a small-diameter opening portion of a dust cover and a knuckle. The ball joint connects the knuckle to a stud, and a ball head provided on the end of the stud is accommodated in a socket in a rockable and rotatable manner. The dust cover connects a large-diameter opening that surrounds the socket, which houses the ball head, and a small-diameter opening portion, which surrounds the stud, by a membrane. The ferrule ring includes an annular portion that suppresses the entry of dust through a cutout produced when, for example, a pinch bolt type knuckle is adopted, and has an inclined portion, which inclines toward the dust cover, on the outer circumferential edge thereof.
Provided are a container with which the outflow rate of a fluid can easily be controlled, and which can be caused to function as part of a configuration of a diaphragm pump, as well as a microfluidic device and a diaphragm pump. The container includes a case body 110 that includes a tubular portion in which a fluid is to be sealed, a thin film 200 that closes an opening on one end side of the tubular portion and that is to be punctured so as to form an outflow port for the fluid R therein, and a diaphragm 300 that closes an opening on the other end side of the tubular portion.
The present invention provides a frozen composition containing nucleic acid-encapsulated lipid nanoparticles, wherein the nucleic acid-encapsulated lipid nanoparticles contain an ionic lipid represented by formula (1), and the molar ratio of amino groups of the ionic lipid represented by formula (1) to nucleic acid phosphate groups is 7-250 inclusive (the definitions of the symbols in formula (1) are as described in the description).
A61K 47/20 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
Provided is a flame-retardant rubber composition including an ethylene-α-olefin-non-conjugated diene copolymer, aluminum hydroxide, an alkyl-modified silane coupling agent, and a hydrocarbon-based plasticizer. An amount of the aluminum hydroxide is 60 mass % or more of the flame-retardant rubber composition, a total amount of the alkyl-modified silane coupling agent and the hydrocarbon-based plasticizer is 8 mass % or less of the flame-retardant rubber composition, and an amount of the alkyl-modified silane coupling agent is 5 mass % or more of the aluminum hydroxide. The flame-retardant rubber composition has excellent flame retardancy, physical properties suitable as a sealing material, and low environmental impact.
A sealing apparatus is provided. The sealing apparatus is arranged between two members facing each other for sealing a space between the two members. The sealing apparatus comprises a sealing body in contact with the space, in which the sealing body has a tensile strength of 10 MPa or more measured in accordance with the provisions of JIS K 6251: 2017, an elongation at break of 200% or more measured in accordance with the provisions of JIS K 6251: 2017, a TR10 temperature of −40° C. or lower in a low-temperature elastic recovery test, measured in accordance with the provisions of JIS K 6261-4: 2017, and a compression set at 100° C. with an elapsed time of 70 hours in a shape of a G25 O-ring as described in the provisions of JIS B 2401-1: 2012, measured in accordance with the provisions of JIS K 6262: 2013, of 40% or less.
F16J 15/02 - Sealings between relatively-stationary surfaces
H01M 8/04082 - Arrangements for control of reactant parameters, e.g. pressure or concentration
54.
CATIONIC LIPID HAVING DISULFIDE BOND, LIPID MEMBRANE STRUCTURE INCLUDING SAME, NUCLEIC ACID INTRODUCTION AGENT AND PHARMACEUTICAL COMPOSITION CONTAINING ANY ONE OF SAME, METHOD FOR INTRODUCING NUCLEIC ACID INTO CELL OR TARGET CELL, AND METHOD FOR PRODUCING CELLULAR PHARMACEUTICAL
National University Corporation Chiba University (Japan)
Inventor
Tamada, Masamichi
Tanaka, Tokihiro
Tamagawa, Shinya
Tange, Kota
Nakai, Yuta
Ito, Kasumi
Akita, Hidetaka
Tanaka, Hiroki
Sakurai, Yu
Sato, Yuka
Abstract
The present invention provides a cationic lipid that can be used as a nucleic acid delivery carrier with good intracellular dynamics, a lipid membrane structure containing the same, a nucleic acid-introducing agent and a pharmaceutical composition containing any of them, a method for introducing nucleic acid into cells or target cells, and a method for producing a cell medicine. A cationic lipid represented by the formula (1) (definitions of symbols in the formula are as described in the specification), a lipid membrane structure using the aforementioned cationic lipid, a nucleic acid-introducing agent and a pharmaceutical composition using the aforementioned cationic lipid or the aforementioned lipid membrane structure, a method for introducing nucleic acid into cells or target cells by using the aforementioned nucleic acid-introducing agent, and a method for producing a cell medicine by using the aforementioned nucleic acid-introducing agent.
The present invention provides a cationic lipid that can be used as a nucleic acid delivery carrier with good intracellular dynamics, a lipid membrane structure containing the same, a nucleic acid-introducing agent and a pharmaceutical composition containing any of them, a method for introducing nucleic acid into cells or target cells, and a method for producing a cell medicine. A cationic lipid represented by the formula (1) (definitions of symbols in the formula are as described in the specification), a lipid membrane structure using the aforementioned cationic lipid, a nucleic acid-introducing agent and a pharmaceutical composition using the aforementioned cationic lipid or the aforementioned lipid membrane structure, a method for introducing nucleic acid into cells or target cells by using the aforementioned nucleic acid-introducing agent, and a method for producing a cell medicine by using the aforementioned nucleic acid-introducing agent.
A61K 9/1272 - Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
C07C 323/12 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
C07C 323/25 - Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
C07C 323/41 - Y being a hydrogen or an acyclic carbon atom
C07D 211/14 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle
55.
METHOD FOR PRODUCING ARYL ESTER-CONTAINING CARBOXYLIC ACID AND METHOD FOR PRODUCING CATIONIC LIPID
The present invention provides a method for producing a high-purity carboxylic acid containing aryl ester that suppresses generation of oligomers and does not require a purification step with low productivity such as column chromatography and the like, and a method for producing cationic lipids. A method for producing an aryl ester-containing carboxylic acid (1), including the following steps: 1) a step of reacting a compound (7) using potassium tert-butoxide and tert-butyl alcohol in the presence of an aprotic solvent to obtain a compound (11), 2) a step of reacting the compound (11) with a compound (13) using a condensing agent to obtain a compound (12), and 3) a step of deprotecting the tert-butyl group of the compound (12) by using trifluoromethanesulfonic acid, methanesulfonic acid, a combination of TMS-Cl and sodium iodide, or TMS-I in an organic solvent to obtain the compound (1) (A is phenyl having —O—C(═O)R20 group, etc., and B is phenyl having hydroxy group, etc.).
The present invention provides a method for producing a high-purity carboxylic acid containing aryl ester that suppresses generation of oligomers and does not require a purification step with low productivity such as column chromatography and the like, and a method for producing cationic lipids. A method for producing an aryl ester-containing carboxylic acid (1), including the following steps: 1) a step of reacting a compound (7) using potassium tert-butoxide and tert-butyl alcohol in the presence of an aprotic solvent to obtain a compound (11), 2) a step of reacting the compound (11) with a compound (13) using a condensing agent to obtain a compound (12), and 3) a step of deprotecting the tert-butyl group of the compound (12) by using trifluoromethanesulfonic acid, methanesulfonic acid, a combination of TMS-Cl and sodium iodide, or TMS-I in an organic solvent to obtain the compound (1) (A is phenyl having —O—C(═O)R20 group, etc., and B is phenyl having hydroxy group, etc.).
C07D 211/24 - Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulfur atoms by sulfur atoms to which a second hetero atom is attached
National University Corporation Ibaraki University (Japan)
Dinow Inc. (Japan)
NOK CORPORATION (Japan)
Inventor
Nakamura, Asako
Takahashi, Kenta
Chihara, Yuma
Komori, Takayuki
Fujisawa, Naohiro
Abstract
The present invention addresses the problem of providing a white blood cell capturing device that captures white blood cells with high efficiency while being unsusceptible to capturing other material. The problem is solved by this white blood cell capturing device, which captures white blood cells included in a blood-containing liquid, and includes a sample entrance, a buffer entrance, a white blood cell separation unit, a main part, an auxiliary part, and an exit, wherein: the main part has a flat portion and a large number of protrusions provided thereon, the main part being configured such that a buffer which has entered from the entrance passes above the main part and is discharged from the exit; the protrusions are provided in layered form on the surface of the flat portion, each layer includes a plurality of the protrusions, and the protrusions are configured such that a buffer that has passed through a layer on the entrance side passes through a layer on the exit side adjacent thereto; and the capture part faces the exit side of all or some of the bypass parts in a specific layer, and is disposed as a part of a separate layer adjacent thereto.
Provided is a copolymer that imparts hydrophilicity and antifouling properties to a contact lens by a simple method and maintains lasting effects thereof. A copolymer (P) comprises constituent units represented by formula (1a) and formula (1b), the molar ratio na:nb of the constituent units being 10-99: 1-90, and the weight average molecular weight being 10,000-2,000,000. (In formula (1a), R1 is a hydrogen atom or a methyl group, and W1 is O or NR2, where R2 is H or a C1-4 alkyl group.) (In formula (1b), R1 is a hydrogen atom or a methyl group, R2 is H or a C1-4 alkyl group, L1 is a C1-5 alkylene group, or a C1-5 alkylene group including one or more hydroxy groups, and m is an integer of 2 or 3.)
METHOD FOR PRODUCING NUCLEIC ACID-ENCAPSULATED LIPID NANOPARTICLES, METHOD FOR PRODUCING PHARMACEUTICAL COMPOSITION CONTAINING SAID LIPID NANOPARTICLES, AND METHOD FOR INTRODUCING NUCLEIC ACID INTO CELL OR TARGET CELL
National University Corporation Chiba University (Japan)
Inventor
Tange, Kota
Nakai, Yuta
Akita, Hidetaka
Tanaka, Hiroki
Sakurai, Yu
Yamakawa, Takuma
Sato, Yuka
Abstract
The present invention provides a method for producing nucleic acid-encapsulated lipid nanoparticles, which can encapsulate any nucleic acid with high efficiency and with ease. A method for producing nucleic acid-encapsulated lipid nanoparticles, including the following steps: a) a step of preparing a suspension of lipid nanoparticles not containing a nucleic acid, by mixing an alcohol solution containing ionic lipid, sterol and PEG lipid with an acidic buffer having a buffering action at pH 1 to 6.5, and b) a step of mixing, without lyophilization, the suspension of the lipid nanoparticles obtained in step a with an aqueous solution containing a nucleic acid and optionally containing 0 to 25 v/v % alcohol, and optionally incubating the mixture at 0 to 95° C. for 0 to 60 min to obtain nucleic acid-encapsulated lipid nanoparticles.
Provided is a wiring module including a flexible printed board; and a metal piece, in which the flexible printed board has a land and a wiring connected to the land, the metal piece has an upper surface, a lower surface, a through-hole, and a projecting portion, the lower surface of the metal piece is solder-joined to the land, the through-hole is formed in a thickness direction of the metal piece, the projecting portion is formed so as to project from at least part of an edge of the through-hole to above the upper surface of the metal piece, the projecting portion has a plated portion and a non-plated portion, the plated portion is provided at an inner peripheral surface of the projecting portion facing the through-hole, and the non-plated portion is provided at an end surface of a projecting end of the projecting portion.
A method for producing a high molecular weight polyoxyethylene derivative having a derivatized hydroxyl group is disclosed. The method includes labeling an unreacted high molecular weight polyoxyethylene compound having a hydroxy group using a labeling reagent in a deuterated solvent, and quantitating a labeled solution by a pre-saturation method and a proton nuclear magnetic resonance spectroscopy using inverse gated decoupling. The method allows a prompt quantitation of unreacted high molecular weight polyoxyethylene compound having a hydroxy group with a high accuracy.
C08G 65/332 - Polymers modified by chemical after-treatment with organic compounds containing oxygen containing carboxyl groups, or halides or esters thereof
C08G 65/331 - Polymers modified by chemical after-treatment with organic compounds containing oxygen
C08G 65/333 - Polymers modified by chemical after-treatment with organic compounds containing nitrogen
C08G 65/334 - Polymers modified by chemical after-treatment with organic compounds containing sulfur
G01N 24/08 - Investigating or analysing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
61.
METHOD FOR PRODUCING ACTIVE CARBONIC ACID ESTER OF POLYETHYLENE GLYCOL, AND ACTIVE CARBONIC ACID ESTER OF POLYETHYLENE GLYCOL
Activated polyethylene glycol with high purity can be obtained by a method including:
a step (a) of reacting polyethylene glycol having a hydroxyl group with one or more active carbonic acid reagents selected from the group consisting of disuccinimidyl carbonate and p-nitrophenylchloroformate in presence of a base in an aprotic solvent which is immiscible with water, to obtain a composition containing an active carbonic acid ester of polyethylene glycol and the active carbonic acid reagent being unreacted,
a step (b) of partially removing the active carbonic acid reagent by filtering the composition obtained in the step (a), and then obtaining a composition by adding an alcohol containing an acidic functional group to react with the unreacted active carbonic acid reagent, and
a step (c) of removing a reaction product of the alcohol containing an acidic functional group and the active carbonic acid reagent, the alcohol containing an acidic functional group, and a decomposition product of the active carbonic acid reagent by washing the composition obtained in the step (b) with water.
C08G 65/46 - Post-polymerisation treatment, e.g. recovery, purification, drying
62.
LIPID NANOPARTICLES FOR DELIVERING NUCLEIC ACID TO PERIPHERAL BLOOD MONONUCLEAR CELLS, AND METHOD FOR DELIVERING NUCLEIC ACID TO PERIPHERAL BLOOD MONONUCLEAR CELLS USING SAME
National University Corporation Chiba Unversity (Japan)
Inventor
Nakai, Yuta
Tange, Kota
Akita, Hidetaka
Tanaka, Hiroki
Sakurai, Yu
Miyama, Ryo
Abstract
The present invention provides lipid nanoparticles for delivering nucleic acid to peripheral blood mononuclear cells that can improve the efficiency of nucleic acid delivery to peripheral blood mononuclear cells, and a method for delivering nucleic acid to peripheral blood mononuclear cells by using same. Lipid nanoparticles for use in delivering a nucleic acid to a peripheral blood mononuclear cell, containing an ionic lipid represented by the formula (1), a phospholipid that is 1,2-diacyl-sn-glycero-3-phosphocholine in which the acyl groups have not less than 20 carbon atoms and at least one of the acyl groups is an alkenoyl group, cholesterol, and a dimyristoylglycerol PEG represented by the formula: CH2(OR6)—CH(OR7)—CH2(OR8) (symbols in the formula are as described in the specification), and a method for delivering a nucleic acids to a peripheral blood mononuclear cell by using same.
The present invention provides lipid nanoparticles for delivering nucleic acid to peripheral blood mononuclear cells that can improve the efficiency of nucleic acid delivery to peripheral blood mononuclear cells, and a method for delivering nucleic acid to peripheral blood mononuclear cells by using same. Lipid nanoparticles for use in delivering a nucleic acid to a peripheral blood mononuclear cell, containing an ionic lipid represented by the formula (1), a phospholipid that is 1,2-diacyl-sn-glycero-3-phosphocholine in which the acyl groups have not less than 20 carbon atoms and at least one of the acyl groups is an alkenoyl group, cholesterol, and a dimyristoylglycerol PEG represented by the formula: CH2(OR6)—CH(OR7)—CH2(OR8) (symbols in the formula are as described in the specification), and a method for delivering a nucleic acids to a peripheral blood mononuclear cell by using same.
C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle
63.
VIBRATION STRUCTURE, PASSIVE RADIATOR, AND SOUND ABSORPTION STRUCTURE
A vibration structure (1) is provided with a vibration mass (10), a support part (20), and an elastic part (30). The vibration mass (10) is a plate-shaped portion. The support part (20) is a portion having a space (21) capable of accommodating the vibration mass (10). The elastic part (30) is an elastically deformable portion that connects the vibration mass (10) to the support part (20). The elastic part (30) extends along an outer peripheral edge (13) of the vibration mass (10), and supports the vibration mass (10) such that the vibration mass can vibrate in a direction in which the front surface (11) and the back surface (12) of the vibration mass (10) face the support part (20). The vibration mass (10) has a plurality of corners (14) on the outer peripheral edge (13). The width (W) of a plurality of corners (31) of the elastic part (30) respectively located at the plurality of corners (14) of the vibration mass (10) is wider than the width (w) of sides (32, 33) of the elastic part (30). The widths (W, w) are each distances in directions in which the front surface (11) and the back surface (12) extend.
H04R 1/28 - Transducer mountings or enclosures designed for specific frequency responseTransducer enclosures modified by provision of mechanical or acoustic impedances, e.g. resonator, damping means
G10K 13/00 - Cones, diaphragms, or the like, for emitting or receiving sound in general
A pressure-regulating valve for a power storage module includes a valve body portion that opens in response to pressure in a power storage module to release the pressure in the power storage module, and an electrolyte reservoir portion provided between the valve body portion and the power storage module, and capable of storing the electrolyte leaking from an inside of the power storage module to a valve body portion side.
NATIONAL UNIVERSITY CORPORATION CHIBA UNIVERSITY (Japan)
Inventor
Tange, Kota
Yoshioka, Hiroki
Nakai, Yuta
Akita, Hidetaka
Sakurai, Yu
Tanaka, Hiroki
Yoshikawa, Keito
Abstract
The present invention provides a lipid nanoparticle used for delivering a nucleic acid to a lymphatic endothelial cell, including an ionic lipid represented by the formula (1), cholesterol, and a dimyristoylglycerol PEG with a number average molecular weight of PEG chain of 1,000 to 3,000, wherein an amount of the dimyristoylglycerol PEG is not less than 3 mol % with respect to the total of the ionic lipid represented by the formula (1) and the cholesterol (the symbols in the formula (1) are as defined in the specification).
The present invention provides a lipid nanoparticle used for delivering a nucleic acid to a lymphatic endothelial cell, including an ionic lipid represented by the formula (1), cholesterol, and a dimyristoylglycerol PEG with a number average molecular weight of PEG chain of 1,000 to 3,000, wherein an amount of the dimyristoylglycerol PEG is not less than 3 mol % with respect to the total of the ionic lipid represented by the formula (1) and the cholesterol (the symbols in the formula (1) are as defined in the specification).
A61K 47/22 - Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
C12N 15/88 - Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using liposome vesicle
66.
NUCLEIC ACID AMPLIFICATION PROMOTER AND TEST METHOD USING SAME
The present invention provides a nucleic acid amplification-promoting agent consisting of a polymer containing a constitutional unit derived from a monomer having a phosphorylcholine group.
C12Q 1/6848 - Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
A sealing device is arranged between two relatively displaceable members containing an object to be sealed, for example, a drive shaft of an electric vehicle, and a housing for the drive shaft. A sealing body made of conductive rubber provided in the sealing device is fixed in a state of contact with the housing by an outer peripheral seal, and brings a sealing surface provided on a conductive lip into surface contact with the drive shaft to seal the object. A grease groove is provided on the sealing surface to retain grease having conductivity. The grease is filled between the drive shaft and the sealing surface, and forms a conducting circuit along with the sealing body which makes the drive shaft acting as an antenna for electromagnetic noise and the housing conductive.
F16J 15/3232 - Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings with at least one lip having two or more lips
F16J 15/16 - Sealings between relatively-moving surfaces
F16J 15/3212 - Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings with at least one lip provided with tension elements, e.g. elastic rings with metal springs
F16J 15/3284 - Sealings between relatively-moving surfaces with elastic sealings, e.g. O-rings characterised by their structureSelection of materials
An annular gasket made of elastomer contacts with an inner peripheral surface of a hole in an outer member and an outer peripheral surface of an inner member to shut off an inner space of the outer member from an atmospheric space. The gasket includes a first wider portion, a second wider portion, a third wider portion, a first narrower portion, and a second narrower portion. The maximum distance between a first outer peripheral groove and the inner peripheral surface of the hole, the maximum distance between a second outer peripheral groove and the inner peripheral surface of the hole, the maximum distance between a first inner peripheral groove and the outer peripheral surface of the inner member, and the maximum distance between a second inner peripheral groove and the outer peripheral surface of the inner member are each at least 0.05 mm in a compressed state of the gasket.
KOCHI PREFECTURAL PUBLIC UNIVERSITY CORPORATION (Japan)
Inventor
Fujimura, Toshinobu
Nakasato, Katsumi
Iizuka, Muneaki
Sato, Kyohei
Kawaharamura, Toshiyuki
Fukue, Miyabi
Liu, Li
Abstract
Provided is a heat dissipation substrate in which a metal member is provided adjacent to one surface of an insulating layer. The metal member has a material made from copper, a copper alloy, aluminum, or an aluminum alloy and has a sheet shape having a thickness of 0.2-20 mm inclusive. The insulating layer is formed from a first insulating layer and a second insulating layer, and the first insulating layer and the second insulating layer are metal oxide layers including mutually different aluminum oxides. The first insulating layer is a metal oxide layer having a thickness of 0.01-0.2 μm inclusive and a porosity of 10% or less. The second insulating layer is a metal oxide layer having a thickness of 0.3-30 μm inclusive and a porosity of 10% or less.
A crude polyethylene glycol derivative containing a polyethylene glycol derivative having at least one selected from the group consisting of a functional group capable of reacting with a bio-related substance, a functional group serving as a precursor of the functional group, and a protective group for the functional group at a terminal thereof, and impurities are mixed with a mixed organic solvent made from an organic solvent A and an organic solvent B to form a slurry, and the slurry is subjected to repulping washing, and then the polyethylene glycol derivative is recovered from the mixed organic solvent, and the polyethylene glycol derivative is dissolved in a good solvent and then the polyethylene glycol derivative is recovered, and the relation: 0.5≤Y×T≤30 is satisfied as defined herein.
This shock-absorbing stopper is disposed between a flange part having a first annular surface protruding from the outer circumferential surface of a shaft movable in the axial direction and a protruding part having a second annular surface that protrudes toward the shaft from the inner circumferential surface of a tubular housing accommodating the shaft, the second annular surface being apart from the first annular surface. The shock-absorbing stopper comprises: a metal ring in contact with the first annular surface; an annular shock-absorbing body provided between the metal ring and the second annular surface and joined to the metal ring; and an annular member provided between the shock-absorbing body and the second annular surface and joined to the shock-absorbing body, wherein the shock-absorbing body contains a rubber-like elastic material, the metal ring is an annular flat plate, the annular member is apart from the metal ring and provided on the radially inner side of the shock-absorbing body, and the annular member is of higher rigidity than the shock-absorbing body.
A dust cover includes a cover, a cylinder including a first end in a first direction along a central axis of the cylinder and a second end opposite to the first end, an annular first portion connected to the first end, and an annular second portion extending from an outer circumferential surface of the cylinder radially outward. The first portion includes an outer circumferential surface including a first surface inclined radially outward relative to the central axis. The second portion includes a surface facing in the first direction and including a second surface disposed in the first direction from a reference plane perpendicular to the central axis and including the second end, the second surface being at an angle greater than 0 degrees relative to the reference plane. The cover includes an annular seal surrounding the cylinder and being in contact with the first surface and the second surface.
The problem addressed by the present application is to provide a rubber composition having excellent vibration-proofing and sound-deadening properties. The rubber composition disclosed by the present application is a crosslinked rubber composition containing ethylene propylene diene rubber (EPDM), 110–190 parts by mass of carbon black per 100 parts by mass of the ethylene propylene diene rubber, 10–35 parts by mass of an aromatic modified terpene resin per 100 parts by mass of the ethylene propylene diene rubber, a crosslinking agent, and oil. The nitrogen adsorption specific surface area of the carbon black is 70–120 m2/g, the iodine adsorption capacity is 70–125 mg/g, and the DBP oil absorption capacity is 50–100 cm3/100 g.
C08L 23/16 - Ethene-propene or ethene-propene-diene copolymers
C08L 45/02 - Compositions of homopolymers or copolymers of compounds having no unsaturated aliphatic radicals in a side chain, and having one or more carbon-to-carbon double bonds in a carbocyclic or in a heterocyclic ring systemCompositions of derivatives of such polymers of coumarone-indene polymers
C08L 91/00 - Compositions of oils, fats or waxesCompositions of derivatives thereof
The sunscreen composition contains 2-51 mass% of a component (A), 9-80 mass% of a component (B), 0.1-14 mass% of a component (C), 0.1-10 mass% of a component (D), 5-40 mass% of a component (E), and 6-57 mass% of a component (F). The mass ratio ((A)/(B)) of the component (A) and the component (B) is 5/95-60/40. Component (A): isoparaffin having an average carbon number of 50-250. Component (B): isoparaffin having an average carbon number of 20-24. Component (C): an emulsifier such as a sorbitan fatty acid ester having an HLB of 2-10. Component (D): a polyhydric alcohol that has 2-6 carbon atoms and is dihydric or trihydric. Component (E): an ultraviolet scattering agent. Component (F): water.
An ultrasonic probe includes at least one piezoelectric element configured to transmit and receive ultrasonic waves. The at least one piezoelectric element includes a piezoelectric material formed by a sol-gel process, and at least one electrode being in contact with the piezoelectric material and containing a conductive elastomer.
H10N 30/87 - Electrodes or interconnections, e.g. leads or terminals
B06B 1/06 - Processes or apparatus for generating mechanical vibrations of infrasonic, sonic or ultrasonic frequency making use of electrical energy operating with piezoelectric effect or with electrostriction
H10N 30/06 - Forming electrodes or interconnections, e.g. leads or terminals
H10N 30/078 - Forming of piezoelectric or electrostrictive parts or bodies on an electrical element or another base by depositing piezoelectric or electrostrictive layers, e.g. aerosol or screen printing by liquid phase deposition by sol-gel deposition
A torsional damper is provided having a hub in which a boss adapted to be fixed to a rotating shaft, such as a crankshaft of an engine, and an annular rim are integrally provided via a plurality of stays, and an annular vibration ring connected to an outer circumferential surface of the rim via an elastic body. The stays have a circumferential width dimension that does not exceed one-quarter of the wavelength of the axial resonant frequency of the hub, and are thickened within a range in which the axial thickness dimension does not exceed one-half of the wavelength of the axial resonant frequency of the hub. Thickening of the stays is implemented by, for example, setting the axial thickness dimension thereof to a length equal to or more than one-quarter of the wavelength of the axial resonant frequency of the hub. The stays have an axially inclined shape.
F02B 67/06 - Engines characterised by the arrangement of auxiliary apparatus not being otherwise provided for, e.g. the apparatus having different functionsDriving auxiliary apparatus from engines, not otherwise provided for of mechanically-driven auxiliary apparatus driven by means of chains, belts, or like endless members
77.
FLOW PATH DEVICE AND METHOD FOR MANUFACTURING SAME
A flow path device (1) is provided with: a base (4) having a first surface (4a) and a second surface (4b) that face away from each other; and a pair of first electrode (10) and second electrode (11). The base (4) has a flow path (7) that extends along the first surface (4a) and the second surface (4b), and the pair of first electrode (10) and second electrode (11) form an electric field that intersects the flow path (7) along a direction in which the first surface (4a) and the second surface (4b) face away.
Provided is an additive for CMP, which contains a polycarboxylic acid-based copolymer that contains, as constituent monomers, 5-95 mol% of (a) a compound represented by formula (1): R1O(AO)nR2(wherein R1represents a hydrocarbon group having 1-18 carbon atoms; R2 represents an unsaturated hydrocarbon group having 2-5 carbon atoms; AO represents one or more types of oxyalkylene groups each having 2-4 carbon atoms; and n represents the average number of moles of oxyalkylene groups added and is a numerical value of 1-100), 0-95 mol% of (b) a maleic acid-based compound, and 0-60 mol% of (c) a compound copolymerizable with the compound (a) and the compound (b) (wherein the total amount of the compound (b) and the compound (c) is 5-95 mol%) and that has a weight average molecular weight of 14,000 or less. As a result, it becomes possible to provide a technique that can prevent the aggregation of abrasive grains and can improve a polishing speed without using grains of a surface-modified metal oxide or the like as the abrasive grains.
H01L 21/304 - Mechanical treatment, e.g. grinding, polishing, cutting
B24B 37/00 - Lapping machines or devicesAccessories
C08F 16/12 - Homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an alcohol, ether, aldehydo, ketonic, acetal, or ketal radical by an ether radical
C09G 1/02 - Polishing compositions containing abrasives or grinding agents
A rubber product capable of easily and accurately detecting the presence or absence of leakage and a position of the leakage is provided. A rubber product includes a gas chromic material that changes a color thereof reversibly or changes an electric resistance value thereof, due to oxidation-reduction reaction. The rubber product is a sealing member (sealing product 10) for sealing a gap between two members, wherein the sealing member includes a gas chromic material that changes a color thereof reversibly or changes an electric resistance value thereof, due to oxidation-reduction reaction, and has a ring shape.
G01M 3/22 - Investigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipes, cables, or tubesInvestigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for pipe joints or sealsInvestigating fluid tightness of structures by using fluid or vacuum by detecting the presence of fluid at the leakage point using special tracer materials, e.g. dye, fluorescent material, radioactive material for valves
A61K 8/81 - Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
A61Q 17/04 - Topical preparations for affording protection against sunlight or other radiationTopical sun tanning preparations
81.
ZINC CARBOXYLATE SALT FOR PRODUCTION OF SEMICONDUCTOR NANOPARTICLE
A zinc carboxylate salt used in production of a semiconductor nanoparticle, in which a ratio of carboxylic acids having 8 to 10 carbon atoms in whole of carboxylic acids that form the zinc carboxylate salt is 80.0% by mass or more, and an average branching degree of the whole of the carboxylic acids that form the zinc carboxylate salt is in the range of 1.1 to 2.9. The present invention can provide a zinc salt used for easily producing a semiconductor nanoparticle having a core/shell type structure that has excellent optical properties in the case where two or more types of shell precursors are used to produce the semiconductor nanoparticle having a core/shell type structure.
C07C 53/128 - Acids containing more than four carbon atoms the carboxyl group being bound to a carbon atom bound to at least two other carbon atoms, e.g. neo-acids
B82Y 20/00 - Nanooptics, e.g. quantum optics or photonic crystals
B82Y 40/00 - Manufacture or treatment of nanostructures
C07C 53/126 - Acids containing more than four carbon atoms
An antifogging agent composition which contains a copolymer (A), colloidal silica (B) and a solvent (C), wherein: (A) is a (meth)acrylate copolymer obtained from a monomer mixture which contains monomers (a-1) to (a-3); (C) contains water (C-1), a C1-4 monovalent alcohol-based solvent (C-2), a solvent (C-3) which has one or more functional groups per molecule selected from a ketone group, an ester group, two or more ether groups, a thioketone group and an amide group, and has a boiling point of 100-200° C., inclusive, and a glycol ether-based solvent (C-4) represented by general formula (5) (R10—O—R11—OH); and the combined total of (C-1) to (C-4) relative to 100 parts by mass of the combined total of (A) and (B), and the mass ratios of (C-3) and (C-4) relative thereto, are specific amounts. Also disclosed is an antifogging article including an antifogging coating formed from the antifogging agent composition on a base material.
[Problem] The purpose of the present invention is to provide a polyether-modified organopolysiloxane which has good water solubility without impairing the characteristics of siloxane, while having a polyether chain. [Solution] The present invention provides a polyether-modified organopolysiloxane which is represented by formula (1) and has a block copolymer structure comprising a polyblock structure of oxyethylene and a polyblock structure of oxypropylene. (In the formula, each R independently represents a group selected from among an alkyl group having 1 to 10 carbon atoms, an aryl group having 6 to 10 carbon atoms, and an aralkyl group having 7 to 10 carbon atoms; x represents an integer of 1 to 100; and each R1independently represents a group represented by formula (2).) (In the formula, R2 represents an alkyl group having 1 to 12 carbon atoms or an acetyl group; n represents an integer of 2 to 10; a represents an integer of 3 to 60; b represents an integer of 3 to 60; b/(a + b) is within the range of 0.3 to 0.8; and oxypropylene in parentheses with the subscript a and oxyethylene in parentheses with the subscript b respectively have polyblock structures in the sequence shown in formula (2).)
A pressure-regulating valve for a power storage module is a pressure-regulating valve for a power storage module in which a case accommodating a valve body in a valve chamber is attached to a power storage device (10), and the case has a sealing surface that is provided with a sealing member and is to contact the power storage device, and an attaching portion attachable to the power storage device by moving along a predetermined slide direction along the sealing surface.
A cushioning stopper includes a ring shaped elastic body that is mountable in a mounting space, and an elastic body restraining member covering part of a periphery of the elastic body and preventing expansion of the elastic body. The elastic body has a first body between two axially displaceable members, and compressed in an axial direction by the two members to expand radially outward when the distance between the two members is reduced, and a second body projecting outward from a peripheral surface of the first body on one end in the axial direction, the elastic body restraining member has an L-shaped cross section covering an end face on the one end side of the elastic body and a peripheral surface of the second body, and the second body has a recess on an end face opposite to the one end side in the axial direction, which is recessed inwardly.
An acetal-type releasable polyoxyethylene derivative containing an amino group, the derivative being characterised by being represented by a specific formula; a method for producing the same; and an acetal-type releasable polyoxyethylene conjugate containing an amino group.
A gasket (1) includes a body portion (10) in an annular shape having a basal surface (11) to contact a bottom surface (113) of a groove(110) and a top surface (12) to contact a second member (200) and extending over an entire circumferential direction of the gasket (1), a first protrusion pair (20) protruding from the body portion (10) respectively toward both side surfaces (111, 112) of the groove (110) and extending over the entire circumferential direction; and a second protrusion pair (30) protruding from the first protrusion pair (20) respectively toward both the side surfaces (111, 112). Respective second protrusions (31, 32) of the second protrusion pair (30) are disposed at a same position in the circumferential direction, and tip ends (31f, 32f) of the respective second protrusions (31, 32) are formed in a planar shape to be along the side surfaces of the groove (110). A first gasket width (W1) of the gasket (1) is smaller than a groove width (W0), and a second gasket width (W2) is larger than the groove width (W0).
A ketal-type releasable polyoxyethylene derivative is expressed by the Formula (1), (2), (3) or (4) as defined herein, and is to be cleaved under a physiological condition, and in the Formulae (1), (2), (3) and (4), B1 represents a hydrogen atom or —C(R1)(R2)OC(O)E1, E1 represents a leaving group, P1 represents a residue obtained by removing a terminal hydroxyl group from a polyoxyethylene derivative having the terminal hydroxyl group, w represents an integer of 1 to 8, R1, R2, R3, R4, R5 and R12 each independently represent a hydrocarbon group having 1 to 10 carbon atoms or a hydrogen atom, R6 represents an optionally substituted hydrocarbon group having 1 to 24 carbon atoms, R7, R8, R9, R10 and R11 each independently represent an electron-withdrawing substituent, an electron-donating substituent, or a hydrogen atom, and m represents 0 or 1.
The present invention provides a cryoprotectant for cells that contains an amphoteric polymer having a specific cationic group and a specific anionic group, a hydrophobic amino acid, and a water-soluble cellulose.
A flow path member that forms a flow path through which a refrigerant flows by being bonded to a plate-shaped member, the flow path member comprising: a plate part that has a first surface and a second surface facing in the opposite direction to the first surface and that is configured from an elastic material; a first connection part that protrudes from the first surface; and a second connection part that protrudes from the first surface. An introduction port for introducing a refrigerant into the flow path is provided on the outermost end surface of the first connection part, a discharge port for discharging the refrigerant from the flow path is provided on the outermost end surface of the second connection part, and a first opening that communicates with the introduction port and a second opening that communicates with the discharge port are provided in the second surface.
The present invention relates to a rubber composition containing a fluorosilicone rubber and silver particles, and a bioelectrode containing the rubber composition.
This hair cosmetic contains (A) 0.1-12 mass% of isoparaffin in which the average number of carbon atoms is 50-250, (B) 0.2-19 mass% of isoparaffin in which the average number of carbon atoms is 20-24, (C) 0.5-5 mass% of at least one compound selected from the group consisting of a quaternary ammonium salt represented by formula (1) and an aliphatic amidoamine represented by formula (2) and salts thereof, (D) 1-10 mass% of an alcohol having 14-24 carbon atoms, and water, the mass ratio ((A)/(B)) between (A) and (B) being 1/20-3/2.
The present invention provides a method for producing a highly-pure branched PEG compound, the method comprising: a step (1a) for mixing, in the presence of a solvent, a porous metal complex with a mixture containing a branched PEG compound and, as an impurity, a linear PEG compound to adsorb the linear PEG compound on the porous metal complex; a step (2a) for removing the porous metal complex having adsorbed the linear PEG compound from the mixture containing the branched PEG compound and the porous metal complex having adsorbed the linear PEG compound to obtain a solution containing the branched PEG compound; and a step (3) for recovering the branched PEG compound from the solution containing the branched PEG compound.
C08G 65/30 - Post-polymerisation treatment, e.g. recovery, purification, drying
B01D 15/00 - Separating processes involving the treatment of liquids with solid sorbentsApparatus therefor
B01J 20/22 - Solid sorbent compositions or filter aid compositionsSorbents for chromatographyProcesses for preparing, regenerating or reactivating thereof comprising organic material
The present invention provides a stabilizer for a nucleic acid solution, which is a polymer containing a structural unit derived from a monomer represented by formula (1), wherein the definition of symbols in the formula is as described in the description.
A sealing device (1) is for sealing an annular gap. The sealing device (1) is provided with one seal ring (2). The one seal ring (2) exhibits desired sealing performance with respect to a fluid even in a low-temperature environment.
A method for producing a polyethylene glycol derivative having a carboxyl group at a terminal has a step 1, a step 2, a step 3, and a step 4. Step 1: A polyethylene glycol compound is subjected to an oxidation reaction using an N-oxyl compound to obtain a polyethylene glycol derivative having a carboxyl group at a terminal. A reducing agent is then added to quench the oxidation reaction to obtain a mixed aqueous solution containing a reduced form of the N-oxyl compound and a polyethylene glycol derivative having a carboxyl group at a terminal. Step 2: The mixed aqueous solution which has been adjusted to a pH of 3.0 or less is mixed with an organic solvent containing one or more selected from the group consisting of aromatic hydrocarbons, carboxylic acid alkyl esters, and halogenated hydrocarbons, at 0°C or higher, and the mixture is separated into an organic layer and a water layer. Step 3: The organic layer obtained in step 2 and an aqueous solution adjusted to a pH of 3.0 or less are mixed at 0°C or higher, and the mixture is separated into an organic layer and a water layer. Step 4: A polyethylene glycol derivative having a carboxyl group is recovered by concentrating the organic layer obtained in step 3.
A pressure regulating valve is attached to each of a plurality of power storage modules. The pressure regulating valve allows internal spaces of the power storage modules to be open, respectively, and has a short-circuit preventing structure for preventing an electrolytic solution coming outside of the power storage modules from causing a short circuit with another power storage module or a short circuit between other power storage modules.
H01M 50/325 - Re-sealable arrangements comprising deformable valve members, e.g. elastic or flexible valve members
H01M 50/59 - Means for preventing undesired use or discharge for preventing incorrect connections inside or outside the batteries characterised by the protection means
An ophthalmic composition according to the present invention comprises: (A) 0.01-0.5 w/w% of a copolymer which has structural units represented by formula (1a) to formula (1c), in which the molar ratio a:b:c between the structural units is 100 : 10-400 : 2-50, and which has a weight-average molecular weight of 5,000-2,000,000; (B) 0.001-0.02 w/w% of benzalkonium chloride; and/or (C) 0.001-0.05 w/w% of chlorhexidine gluconate. The present invention makes it possible to provide an ophthalmic composition that exhibits sufficient preservative efficacy and protects corneal cells.
The present invention provides a method for producing ligand-modified lipid nanoparticles encapsulating a nucleic acid, said method comprising the following steps a) to c), etc. Step a) Mixing an alcohol solution comprising an ionic lipid, a sterol, and a PEG lipid with an acidic buffer solution having a pH of 1-6.5, thereby obtaining a suspension of lipid nanoparticles that do not include a nucleic acid. Step b) Mixing the lipid nanoparticles that do not include a nucleic acid with a nucleic acid solution, thereby obtaining a suspension of lipid nanoparticles that encapsulate a nucleic acid. Step c) Mixing the suspension of lipid nanoparticles that encapsulate a nucleic acid with a ligand-bonded lipid, thereby obtaining a suspension of ligand-modified lipid nanoparticles that encapsulate a nucleic acid.
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 47/18 - AminesAmidesUreasQuaternary ammonium compoundsAmino acidsOligopeptides having up to five amino acids
A61K 47/24 - Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
A61K 47/28 - Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseasesGene therapy
A center bearing support suitable for suppressing the decrease in vibration absorbing capability in a high-frequency region is realized.
A center bearing support suitable for suppressing the decrease in vibration absorbing capability in a high-frequency region is realized.
The center bearing support includes an outer ring 3 that has a cylindrical shape and is attached to a member on a vehicle body side in such a manner that an outer peripheral surface 3b thereof is in contact with the member, an inner ring 2 that has a cylindrical shape and is attached to the center bearing in such a manner that an inner peripheral surface 2b thereof is in contact with an outer periphery of the center bearing, and an elastic body 1 that is connected to an inner peripheral surface 3a of the outer ring 3 and an outer peripheral surface 2a of the inner ring 2 and expands in a bellows-like bent shape which is convex toward one direction along the propeller shaft between the inner peripheral surface 3a of the outer ring 3 and the outer peripheral surface 2a of the inner ring 2, wherein the elastic body 1 includes a base part 15 that has a shape of a bent plate and expands in the bellows-like bent shape while maintaining a constant thickness thereof, between the inner peripheral surface 3a of the outer ring 3 and the outer peripheral surface 2a of the inner ring 2, and a convex part 14 that is layered on a convex surface 11a of a bent portion of the base part 15 and protrudes toward one direction, and the base part 15 and the convex part 14 are integrally formed of an elastic material.
