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Found results for
 patents
1.
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THERAPEUTIC AGENT FOR NON-MOTOR SYMPTOMS ASSOCIATED WITH PARKINSON'S DISEASE
| Application Number |
18089752 |
| Status |
Pending |
| Filing Date |
2022-12-28 |
| First Publication Date |
2023-05-18 |
| Owner |
NEUROINNOVATECH APS (Denmark)
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| Inventor |
- Kato, Taro
- Shimizu, Satoko
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Abstract
The purpose of the present invention is to provide: a therapeutic agent or a recurrence preventive agent for serotonergic system- or dopaminergic system-related diseases, in particular, mental dysfunction symptoms and other non-motor symptoms of Parkinson’s disease; and a method for treating the aforesaid symptoms or preventing the recurrence of the same. A compound represented by formula (1) [wherein each symbol is as defined in the description] or a pharmaceutically acceptable salt thereof can exhibit an effect of treating serotonergic system- or dopaminergic system-related diseases, in particular, mental dysfunction symptoms and other non-motor symptoms of Parkinson’s disease and/or an effect of preventing the recurrence of the same.
The purpose of the present invention is to provide: a therapeutic agent or a recurrence preventive agent for serotonergic system- or dopaminergic system-related diseases, in particular, mental dysfunction symptoms and other non-motor symptoms of Parkinson’s disease; and a method for treating the aforesaid symptoms or preventing the recurrence of the same. A compound represented by formula (1) [wherein each symbol is as defined in the description] or a pharmaceutically acceptable salt thereof can exhibit an effect of treating serotonergic system- or dopaminergic system-related diseases, in particular, mental dysfunction symptoms and other non-motor symptoms of Parkinson’s disease and/or an effect of preventing the recurrence of the same.
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2.
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Therapeutic agent for non-motor symptoms associated with Parkinson's disease
| Application Number |
16476925 |
| Grant Number |
11576897 |
| Status |
In Force |
| Filing Date |
2018-01-12 |
| First Publication Date |
2021-09-30 |
| Grant Date |
2023-02-14 |
| Owner |
NEUROINNOVATECH APS (Denmark)
|
| Inventor |
- Kato, Taro
- Shimizu, Satoko
|
Abstract
The purpose of the present invention is to provide: a therapeutic agent or a recurrence preventive agent for serotonergic system- or dopaminergic system-related diseases, in particular, mental dysfunction symptoms and other non-motor symptoms of Parkinson's disease; and a method for treating the aforesaid symptoms or preventing the recurrence of the same. A compound represented by formula (1) [wherein each symbol is as defined in the description] or a pharmaceutically acceptable salt thereof can exhibit an effect of treating serotonergic system- or dopaminergic system-related diseases, in particular, mental dysfunction symptoms and other non-motor symptoms of Parkinson's disease and/or an effect of preventing the recurrence of the same.
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3.
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Pyrazole compound
| Application Number |
16903646 |
| Grant Number |
11312688 |
| Status |
In Force |
| Filing Date |
2020-06-17 |
| First Publication Date |
2020-10-01 |
| Grant Date |
2022-04-26 |
| Owner |
NEUROINNOVATECH APS (Denmark)
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| Inventor |
- Sasaki, Izumi
- Toyoda, Tomohiro
- Yoshinaga, Hidefumi
- Natsutani, Itaru
- Takahashi, Yoko
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Abstract
2C inverse agonistic action comprising Compound (1):
1-6 alkyl etc.; and X is hydrogen or halogen etc.
IPC Classes ?
- C07D 231/20 - One oxygen atom attached in position 3 or 5
- C07D 231/18 - One oxygen or sulfur atom
- C07D 231/38 - Nitrogen atoms
- C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C07D 493/08 - Bridged systems
- C07D 231/22 - One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
- C07D 231/44 - Oxygen and nitrogen or sulfur and nitrogen atoms
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4.
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Pyrazole compound
| Application Number |
16193232 |
| Grant Number |
10723703 |
| Status |
In Force |
| Filing Date |
2018-11-16 |
| First Publication Date |
2019-03-21 |
| Grant Date |
2020-07-28 |
| Owner |
NEUROINNOVATECH APS (Denmark)
|
| Inventor |
- Sasaki, Izumi
- Toyoda, Tomohiro
- Yoshinaga, Hidefumi
- Natsutani, Itaru
- Takahashi, Yoko
|
Abstract
2C inverse agonistic action comprising Compound (1):
1-6 alkyl etc.; and X is hydrogen or halogen etc.
IPC Classes ?
- C07D 231/20 - One oxygen atom attached in position 3 or 5
- C07D 231/44 - Oxygen and nitrogen or sulfur and nitrogen atoms
- C07D 493/08 - Bridged systems
- C07D 231/22 - One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
- C07D 231/38 - Nitrogen atoms
- C07D 231/18 - One oxygen or sulfur atom
- C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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5.
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Pyrazole compound
| Application Number |
15990026 |
| Grant Number |
10183913 |
| Status |
In Force |
| Filing Date |
2018-05-25 |
| First Publication Date |
2018-09-27 |
| Grant Date |
2019-01-22 |
| Owner |
NEUROINNOVATECH APS (Denmark)
|
| Inventor |
- Sasaki, Izumi
- Toyoda, Tomohiro
- Yoshinaga, Hidefumi
- Natsutani, Itaru
- Takahashi, Yoko
|
Abstract
2C inverse agonistic action comprising Compound (1):
1-6 alkyl etc.; and X is hydrogen or halogen etc.
IPC Classes ?
- C07D 231/20 - One oxygen atom attached in position 3 or 5
- C07D 231/18 - One oxygen or sulfur atom
- C07D 231/38 - Nitrogen atoms
- C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C07D 493/08 - Bridged systems
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6.
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Pyrazole compound
| Application Number |
15491130 |
| Grant Number |
10087146 |
| Status |
In Force |
| Filing Date |
2017-04-19 |
| First Publication Date |
2017-08-03 |
| Grant Date |
2018-10-02 |
| Owner |
NEUROINNOVATECH APS (Denmark)
|
| Inventor |
- Sasaki, Izumi
- Toyoda, Tomohiro
- Yoshinaga, Hidefumi
- Natsutani, Itaru
- Takahashi, Yoko
|
Abstract
2C inverse agonistic action comprising Compound (1):
and X is hydrogen or halogen etc.
IPC Classes ?
- C07D 231/20 - One oxygen atom attached in position 3 or 5
- C07D 231/38 - Nitrogen atoms
- C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C07D 493/08 - Bridged systems
- C07D 231/18 - One oxygen or sulfur atom
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7.
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Pyrazole compound
| Application Number |
14324509 |
| Grant Number |
09663472 |
| Status |
In Force |
| Filing Date |
2014-07-07 |
| First Publication Date |
2014-10-23 |
| Grant Date |
2017-05-30 |
| Owner |
NEUROINNOVATECH APS (Denmark)
|
| Inventor |
- Sasaki, Izumi
- Toyoda, Tomohiro
- Yoshinaga, Hidefumi
- Natsutani, Itaru
- Takahashi, Yoko
|
Abstract
2C inverse agonistic action comprising Compound (1):
1-6 alkyl etc.; and X is hydrogen or halogen etc.
IPC Classes ?
- C07D 231/44 - Oxygen and nitrogen or sulfur and nitrogen atoms
- C07D 493/08 - Bridged systems
- C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C07D 231/18 - One oxygen or sulfur atom
- C07D 231/20 - One oxygen atom attached in position 3 or 5
- C07D 231/38 - Nitrogen atoms
- C07D 231/22 - One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
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8.
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Pyrazole compound
| Application Number |
14041246 |
| Grant Number |
08809383 |
| Status |
In Force |
| Filing Date |
2013-09-30 |
| First Publication Date |
2014-01-30 |
| Grant Date |
2014-08-19 |
| Owner |
NEUROINNOVATECH APS (Denmark)
|
| Inventor |
- Sasaki, Izumi
- Toyoda, Tomohiro
- Yoshinaga, Hidefumi
- Natsutani, Itaru
- Takahashi, Yoko
|
Abstract
2C inverse agonistic action comprising Compound (1):
1-6 alkyl etc.; and X is hydrogen or halogen etc.
IPC Classes ?
- A61K 31/415 - 1,2-Diazoles
- C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C07D 231/22 - One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
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9.
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Pyrazole compound
| Application Number |
13810030 |
| Grant Number |
08569353 |
| Status |
In Force |
| Filing Date |
2011-07-14 |
| First Publication Date |
2013-05-09 |
| Grant Date |
2013-10-29 |
| Owner |
NEUROINNOVATECH APS (Denmark)
|
| Inventor |
- Sasaki, Izumi
- Toyoda, Tomohiro
- Yoshinaga, Hidefumi
- Natsutani, Itaru
- Takahashi, Yoko
|
Abstract
2C inverse agonistic action comprising Compound (1):
1-6 alkyl etc.; and X is hydrogen or halogen etc.
IPC Classes ?
- A61K 31/415 - 1,2-Diazoles
- C07D 405/06 - Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C07D 231/22 - One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
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