Nucletron Operations B.V.

Netherlands

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IPC Class
A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy 62
A61N 5/00 - Radiation therapy 21
A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges 8
A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00) 7
A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves 6
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10 - Medical apparatus and instruments 23
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1.

Brachytherapy applicator

      
Application Number 29865052
Grant Number D1098435
Status In Force
Filing Date 2022-07-05
First Publication Date 2025-10-14
Grant Date 2025-10-14
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Van Manen, Jan Willem

2.

Brachytherapy applicator

      
Application Number 29867871
Grant Number D1077230
Status In Force
Filing Date 2022-11-11
First Publication Date 2025-05-27
Grant Date 2025-05-27
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Van Manen, Jan Willem

3.

Brachytherapy applicator

      
Application Number 29867869
Grant Number D1077229
Status In Force
Filing Date 2022-11-11
First Publication Date 2025-05-27
Grant Date 2025-05-27
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Van Manen, Jan Willem

4.

MARKING ARRANGEMENT, MEDICAL DEVICE, AND SYSTEM FOR RECONSTRUCTING A PLANNED TRAJECTORY

      
Application Number 18720070
Status Pending
Filing Date 2022-12-16
First Publication Date 2025-02-13
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Lie-Kwie-Sjoe, Farahnaz

Abstract

The invention relates to a marking arrangement (10) for marking positions of a medical device along a source trajectory (200), comprising a plurality of markers arranged in series along the source trajectory. Each marker (100) is aligned with the source trajectory and made of a first material and comprises a coating (110), wherein the coating is made of a second material disposed on a surface of the marker. A thickness (T) of the coating is smaller than 1 micrometer, and an interdistance (S) between each marker is smaller than 3 millimeter. The invention further relates to a system for reconstructing a planned trajectory of a medical device, comprising a detection module arranged for detecting the marking arrangement (10) and a treatment calculation module arranged for determining trajectories and dwell times.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

5.

BRACHYTHERAPY SENSOR CABLE

      
Application Number 18705893
Status Pending
Filing Date 2022-11-02
First Publication Date 2025-01-09
Owner NUCLETRON OPERTIONS B.V. (Netherlands)
Inventor
  • Van De Wardt, Cor
  • De Vries, Frits Pieter
  • Henning, Johan

Abstract

According to one aspect, a brachytherapy sensor cable is provided which can be moved through a lumen towards an applicator positioned in a human body and wherein a distal part of the sensor cable comprises a sensor; wherein a hollow passage is formed between the proximal part and the distal part to guide signal wiring of the sensor through the hollow conduit of distal part and proximal part towards a connector that is connectable to the afterloader system.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

6.

MODULAR BRACHYTHERAPY APPLICATOR

      
Application Number 18644790
Status Pending
Filing Date 2024-04-24
First Publication Date 2024-08-22
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van Manen, Jan Willem
  • Arikan, Eylem
  • Van Erp, Wilko

Abstract

Embodiments of the disclosure may be drawn to brachytherapy applicators. Exemplary applicators may include an interstitial tube having a body with a proximal end and a distal end and a central conduit extending from the distal end of the body, wherein the central conduit includes a proximal opening, a distal opening, and a channel extending from the proximal opening to the distal opening, and wherein the proximal opening is offset from an axis of the body. The proximal opening may be configured to fluidly connect to a brachytherapy guide tube, and the channel of the central conduit may be dimensioned to receive at least one of a needle or a catheter therethrough.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

7.

MARKING ARRANGEMENT, MEDICAL DEVICE, AND SYSTEM FOR RECONSTRUCTING A PLANNED TRAJECTORY

      
Application Number NL2022050727
Publication Number 2023/113602
Status In Force
Filing Date 2022-12-16
Publication Date 2023-06-22
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Lie-Kwie-Sjoe, Farahnaz

Abstract

The invention relates to a marking arrangement (10) for marking positions of a medical device along a source trajectory (200), comprising a plurality of markers arranged in series along the source trajectory. Each marker (100) is aligned with the source trajectory and made of a first material and comprises a coating (110), wherein the coating is made of a second material disposed on a surface of the marker. A thickness (T) of the coating is smaller than 1 micrometer, and an interdistance (S) between each marker is smaller than 3 millimeter. The invention further relates to a system for reconstructing a planned trajectory of a medical device, comprising a detection module arranged for detecting the marking arrangement (10) and a treatment calculation module arranged for determining trajectories and dwell times.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

8.

BRACHYTHERAPY SENSOR CABLE

      
Application Number NL2022050617
Publication Number 2023/080781
Status In Force
Filing Date 2022-11-02
Publication Date 2023-05-11
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van De Wardt, Cor
  • De Vries, Frits Pieter
  • Henning, Johan

Abstract

According to one aspect, a brachytherapy sensor cable is provided which can be moved through a lumen towards an applicator positioned in a human body and wherein a distal part of the sensor cable comprises a sensor; wherein a hollow passage is formed between the proximal part and the distal part to guide signal wiring of the sensor through the hollow conduit of distal part and proximal part towards a connector that is connectable to the afterloader system.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

9.

SELECTOR FOR REMOTELY MEDICAL DEVICE / AFTERLOADING

      
Application Number 17754089
Status Pending
Filing Date 2020-09-30
First Publication Date 2022-11-24
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • De Vries, Frits Pieter
  • Schouten, Luuk
  • Welgraven, Aalt Jacob

Abstract

The invention relates to a medical device for transporting and positioning a therapeutic emitting element into a treatment channel to be temporarily placed in or at the body of the patient to treat tumours. The therapeutic emitting element is connected to a transport element and which is driven by at least one drive motor. The device has a connecting element comprising multiple connector openings. The connecting element is used for connecting a transport tube to a respective connector opening. The transport tube is connected to an applicator, needle, tube or catheter for driving the transport element into the treatment channel. The device has a selector mechanism through which the plurality of transport elements are driven. An annular guiding arrangement guides the transport elements into connector openings in the connecting element. The annular guiding arrangement also comprises a plurality of spaced outlets. The inlets of the multiple patterns are each connected to an outlet by guiding channels. Each outlet aligns to a connector opening in the connecting element to allow the transport element from each outlet to be driven into the connector openings.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

10.

Pair of left and right brachytherapy ovoids

      
Application Number 29790307
Grant Number D0966521
Status In Force
Filing Date 2021-11-18
First Publication Date 2022-10-11
Grant Date 2022-10-11
Owner Nucletron Operations B.V. (Netherlands)
Inventor Van Manen, Jan Willem

11.

MARKER FOR MEDICAL IMAGING

      
Application Number 17596989
Status Pending
Filing Date 2020-06-25
First Publication Date 2022-09-29
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Schuurman, Jeroen Anton
  • De Jager, Wim
  • Van Den Berg, Martin
  • Henning, Johan

Abstract

Embodiments of the disclosure may be drawn to brachytherapy markers. Exemplary markers may include an inner ring consisting of one or more of copper, brass, gold, silver, or titanium; an outer coating consisting of one or more of nickel or iron oxide, wherein a thickness of the outer coating may be about 1 μm to about 30 μm; and a central opening, wherein a diameter of the central opening may be about 0.50 mm to about 3.00 mm.

IPC Classes  ?

  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

12.

Sensing apparatus

      
Application Number 17632080
Grant Number 12296194
Status In Force
Filing Date 2020-08-03
First Publication Date 2022-09-01
Grant Date 2025-05-13
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Ferwerda, Sjoerd
  • Van Beek, Martin

Abstract

A sensing apparatus for sensing the presence of a radioactive source, or check-dummy- or sensor cable, at a point along the sensing apparatus during a brachytherapy procedure. The sensing apparatus comprises a transfer tube comprising a first end and a second end. The second end being downstream of the first end. The sensing apparatus further comprises sensing means operable to detect the presence of a radioactive source, or check-dummy- or sensor cable, at a point downstream of the first end of the transfer tube. The reason for the plurality of “prisms” or the semispheres, is that they are orientation independent to the light fibers, simplifying assembly. Alternatively the plurality of prisms may be substituted by two half-spherical “prisms”. Between the prisms, a light blocking surface need to be placed to avoid optical short circuits.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

13.

BRACHYTHERAPY SOURCE ASSEMBLY

      
Application Number 17596987
Status Pending
Filing Date 2020-06-25
First Publication Date 2022-07-28
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Schuurman, Jeroen Anton
  • De Vries, Frits Pieter
  • De Jager, Wim

Abstract

Embodiments of the disclosure may be drawn to brachytherapy source assemblies. Exemplary source assemblies may include a cable made of an electrically non-conductive material and a guide wire coupled to and extending from a distal end of the cable. The guide wire may have a distal end region and a proximal end region, and the guide wire may have a length that is shorter than a length of the cable. The assembly may also include a capsule located at a distal end region of the guide wire, and the capsule may include a chamber configured to contain a radioactive source. The capsule may be formed of a non-ferromagnetic material and may have a ferromagnetic coating that at least partially covers the capsule.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

14.

Pair of left and right brachytherapy ovoids

      
Application Number 29725844
Grant Number D0954956
Status In Force
Filing Date 2020-02-27
First Publication Date 2022-06-14
Grant Date 2022-06-14
Owner Nucletron Operations B.V. (Netherlands)
Inventor Van Manen, Jan Willem

15.

Modular brachytherapy applicator

      
Application Number 17593760
Grant Number 11992701
Status In Force
Filing Date 2020-02-27
First Publication Date 2022-05-26
Grant Date 2024-05-28
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van Manen, Jan Willem
  • Arikan, Eylem
  • Van Erp, Wilko

Abstract

Exemplary brachytherapy applicators may include an interstitial tube having a body with a proximal end and a distal end and a central conduit extending from the distal end of the body, wherein the central conduit includes a proximal opening, a distal opening, and a channel extending from the proximal opening to the distal opening, and wherein the proximal opening is offset from an axis of the body. The proximal opening may be configured to fluidly connect to a brachytherapy guide tube, and the channel of the central conduit may be dimensioned to receive at least one of a needle or a catheter therethrough.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

16.

Brachytherapy applicator

      
Application Number 29725824
Grant Number D0939706
Status In Force
Filing Date 2020-02-27
First Publication Date 2021-12-28
Grant Date 2021-12-28
Owner Nucletron Operations B.V. (Netherlands)
Inventor Van Manen, Jan Willem

17.

SELECTOR FOR REMOTELY MEDICAL DEVICE / AFTERLOADING

      
Application Number NL2020050604
Publication Number 2021/066648
Status In Force
Filing Date 2020-09-30
Publication Date 2021-04-08
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • De Vries, Frits Pieter
  • Schouten, Luuk
  • Welgraven, Aalt Jacob

Abstract

The invention relates to a medical device for transporting and positioning a therapeutic emitting element into a treatment channel to be temporarily placed in or at the body of the patient to treat tumours. The therapeutic emitting element is connected to a transport element and which is driven by at least one drive motor. The device has a connecting element comprising multiple connector openings. The connecting element is used for connecting a transport tube to a respective connector opening. The transport tube is connected to an applicator, needle, tube or catheter for driving the transport element into the treatment channel. The device has a selector mechanism through which the plurality of transport elements are driven. An annular guiding arrangement guides the transport elements into connector openings in the connecting element. The annular guiding arrangement also comprises a plurality of spaced outlets. The inlets of the multiple patterns are each connected to an outlet by guiding channels. Each outlet aligns to a connector opening in the connecting element to allow the transport element from each outlet to be driven into the connector openings.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

18.

A SENSING APPARATUS

      
Application Number NL2020050493
Publication Number 2021/025553
Status In Force
Filing Date 2020-08-03
Publication Date 2021-02-11
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Ferwerda, Sjoerd
  • Van Beek, Martin

Abstract

A sensing apparatus for sensing the presence of a radioactive source, or check- dummy- or sensor cable, at a point along the sensing apparatus during a brachytherapy procedure. The sensing apparatus comprises a transfer tube comprising a first end and a second end. The second end being downstream of the first end. The sensing apparatus further comprises sensing means operable to detect the presence of a radioactive source, or check- dummy- or sensor cable, at a point downstream of the first end of the transfer tube. The reason for the plurality of "prisms" or the semispheres, is that they are orientation independent to the light fibers, simplifying assembly. Alternatively the pluraliy of prisms may be substituted by two half-spherical "prisms". Between the prisms, a light blocking surface need to be placed to avoid optical short circuits.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

19.

BRACHYTHERAPY SOURCE ASSEMBLY

      
Application Number NL2020050416
Publication Number 2020/263091
Status In Force
Filing Date 2020-06-25
Publication Date 2020-12-30
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Schuurman, Jeroen Anton
  • De Vries, Frits Pieter
  • De Jager, Wim

Abstract

Embodiments of the disclosure may be drawn to brachytherapy source assemblies. Exemplary source assemblies may include a cable made of an electrically non-conductive material and a guide wire coupled to and extending from a distal end of the cable. The guide wire may have a distal end region and a proximal end region, and the guide wire may have a length that is shorter than a length of the cable. The assembly may also include a capsule located at a distal end region of the guide wire, and the capsule may include a chamber configured to contain a radioactive source. The capsule may be formed of a non-ferromagnetic material and may have a ferromagnetic coating that at least partially covers the capsule.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

20.

MARKER FOR MEDICAL IMAGING

      
Application Number NL2020050417
Publication Number 2020/263092
Status In Force
Filing Date 2020-06-25
Publication Date 2020-12-30
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Schuurman, Jeroen Anton
  • De Jager, Wim
  • Van Den Berg, Martin
  • Henning, Johan

Abstract

Embodiments of the disclosure may be drawn to brachytherapy markers. Exemplary markers may include an inner ring consisting of one or more of copper, brass, gold, silver, or titanium; an outer coating consisting of one or more of nickel or iron oxide, wherein a thickness of the outer coating may be about 1 μm to about 30 μm; and a central opening, wherein a diameter of the central opening may be about 0.50 mm to about 3.00 mm.

IPC Classes  ?

  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

21.

MODULAR BRACHYTHERAPY APPLICATOR

      
Application Number NL2020050128
Publication Number 2020/197379
Status In Force
Filing Date 2020-02-27
Publication Date 2020-10-01
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van Manen, Jan Willem
  • Arikan, Eylem
  • Van Erp, Wilko

Abstract

Embodiments of the disclosure may be drawn to brachytherapy applicators. Exemplary applicators may include an interstitial tube having a body with a proximal end and a distal end and a central conduit extending from the distal end of the body, wherein the central conduit includes a proximal opening, a distal opening, and a channel extending from the proximal opening to the distal opening, and wherein the proximal opening is offset from an axis of the body. The proximal opening may be configured to fluidly connect to a brachytherapy guide tube, and the channel of the central conduit may be dimensioned to receive at least one of a needle or a catheter there through.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

22.

Wireless afterloader

      
Application Number 16223592
Grant Number 11383099
Status In Force
Filing Date 2018-12-18
First Publication Date 2020-06-18
Grant Date 2022-07-12
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van De Wardt, Cor
  • Henning, Johan

Abstract

Embodiments of the disclosure may be drawn to wireless afterloaders. Exemplary afterloaders may include a central processing unit, a first complex programmable logic device having a memory, a transceiver operably connected to the complex programmable logic device, wherein the transceiver is configured to wirelessly receive data from a second complex programmable logic device separate from the wireless afterloader, and a battery.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • G16H 40/67 - ICT specially adapted for the management or administration of healthcare resources or facilitiesICT specially adapted for the management or operation of medical equipment or devices for the operation of medical equipment or devices for remote operation
  • A61B 17/00 - Surgical instruments, devices or methods
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body

23.

Brachytherapy applicators having ultrasound elements

      
Application Number 15564960
Grant Number 10668299
Status In Force
Filing Date 2016-04-11
First Publication Date 2018-03-15
Grant Date 2020-06-02
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Krechting, Paulus Cornelis Hendrikus Maria
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • De Becker, Jan F. L.
  • Welberg, Anton J. G.

Abstract

A brachytherapy system includes a brachytherapy applicator. The brachytherapy applicator includes an applicator tube and a radiation source configured to deliver radiation to a tumor. At least a portion of the applicator tube is configured to conform to at least a portion of a patient's anatomy. At least one ultrasound element or probe is coupled to or embedded with the applicator tube.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 8/08 - Clinical applications
  • A61B 8/12 - Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
  • A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

24.

Advanced applicator systems and methods

      
Application Number 15532050
Grant Number 10596390
Status In Force
Filing Date 2015-12-04
First Publication Date 2017-10-12
Grant Date 2020-03-24
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Steller, Hendrik
  • Van Erp, Wilhelmus
  • Van Manen, Jan Willem
  • Geheniau, Norbert Johan Lukas

Abstract

Systems, methods, and apparatuses are provided for an advanced gynecological applicator. In accordance with some embodiments, a brachytherapy applicator head and assembly is provided. The assembly may include two ovoid tubes configured to receive radiation sources, the two ovoid tubes combining to form a rounded applicator having a middle opening and comprising a plurality of needle holes to guide interstitial needles. The assembly may also include a central applicator tube configured to receive a radiation source that is located within the middle opening. Additionally, the assembly may include a vaginal cap that includes a tool-free connection to the two ovoid tubes and includes needle guides that align with the needle holes of the two ovoid tubes. The assembly may include a one-piece template for securing interstitial needles. The assembly may further include a tool-free connector to secure the two ovoid tubes to the central applicator tube.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 1/303 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor for the vagina, i.e. vaginoscopes
  • A61B 17/02 - Surgical instruments, devices or methods for holding wounds open, e.g. retractorsTractors

25.

Methods and systems for brachytherapy planning based on imaging data

      
Application Number 15312978
Grant Number 10758745
Status In Force
Filing Date 2015-05-28
First Publication Date 2017-05-04
Grant Date 2020-09-01
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van De Wardt, Cor
  • Krechting, Paulus Cornelis Hendrikus Maria
  • De Becker, Jan Frans Lodewijk
  • Nesvacil, Nicole
  • Kirisits, Christian
  • Pötter, Richard
  • Schmid, Maximilian Paul

Abstract

Systems and methods for generating a radiation therapy treatment plan by using ultrasound images are disclosed. The method includes obtaining a first set of image data representing a first image of an anatomical region that includes a treatment applicator inserted into the anatomical region. The method further includes receiving tracking information indicating a position of the treatment applicator as represented in the first set of image data, obtaining a second set of image data representing a second image of the anatomical region, and combining at least a portion of the first set of image data with the second set of image data. One of the first set and the second set of image data is used to identify a target tissue portion in the anatomical region. The method further includes generating, based on the combined image data, treatment plan information for treating the target tissue portion in the anatomical region.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
  • A61B 8/12 - Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
  • A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
  • A61B 6/12 - Arrangements for detecting or locating foreign bodies
  • A61B 8/08 - Clinical applications
  • A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges
  • A61B 18/00 - Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
  • A61B 17/00 - Surgical instruments, devices or methods

26.

System and method for performing brachytherapy

      
Application Number 15158564
Grant Number 10195460
Status In Force
Filing Date 2016-05-18
First Publication Date 2016-11-24
Grant Date 2019-02-05
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Woudstra, Bas
  • Henning, Johan

Abstract

A system for transporting a source for brachytherapy may include a source guide, a detector, and a controller. The source guide may be configured to guide a source transport for transporting the source, wherein the source guide includes at least one electronic tag. The detector may be configured to detect a frequency signal generated by the at least one electronic tag, wherein the frequency signal varies when the source transport is proximate to the at least one electronic tag. The controller may be configured to receive the frequency signal from the detector and determine a path of the source transport based on the frequency signal. A method for transporting a source used for brachytherapy may include detecting a frequency signal generated by at least one electronic tag associated with a source guide configured to guide a source transport for transporting the source. The frequency may vary when the source transport is proximate to the at least one electronic tag. The method may further include determining a path of the source transport based on the frequency signal.

IPC Classes  ?

  • A61N 5/00 - Radiation therapy
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 90/98 - Identification means for patients or instruments, e.g. tags using electromagnetic means, e.g. transponders

27.

BRACHYTHERAPY APPLICATORS HAVING ULTRASOUND ELEMENTS

      
Application Number NL2016050248
Publication Number 2016/163885
Status In Force
Filing Date 2016-04-11
Publication Date 2016-10-13
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Krechting, Paulus Cornelis Hendrikus Maria
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • De Becker, Jan F.L.
  • Welberg, Anton J.G.

Abstract

A brachytherapy system includes a brachytherapy applicator. The brachytherapy applicator includes an applicator tube and a radiation source configured to deliver radiation to a tumor. At least a portion of the applicator tube is configured to conform to at least a portion of a patient's anatomy. At least one ultrasound element or probe is coupled to or embedded with the applicator tube.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 8/12 - Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
  • A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
  • A61B 8/08 - Clinical applications

28.

Brachytherapy position verification system and methods of use

      
Application Number 14565807
Grant Number 10293178
Status In Force
Filing Date 2014-12-10
First Publication Date 2016-06-16
Grant Date 2019-05-21
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • De Vries, Frits
  • Van Appeldoorn, Adriaan

Abstract

In one embodiment, a verification system for confirming the position of a conduit inserted within a patient may include an elongate control element dimensioned for insertion within the conduit. The control element has a proximal end and a distal end, and a verification element coupled to a distal region. The verification element may be configured to detect the presence of a reference marker associated with the conduit and communicate a signal indicative of the position of the reference marker relative to the verification element. The control element may also be configured to maneuver the verification element along a length of the conduit. The system may also include a drive device coupled to a proximal region of the control element for controlling movement of the control element through the conduit, a controller associated with the verification element and configured to communicate with the verification element, and a signal conductor for conducting the signal between the verification element and the controller.

IPC Classes  ?

  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 17/00 - Surgical instruments, devices or methods
  • A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

29.

ADVANCED APPLICATOR SYSTEMS AND METHODS

      
Application Number IB2015002480
Publication Number 2016/087946
Status In Force
Filing Date 2015-12-04
Publication Date 2016-06-09
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Steller, Hendrik
  • Van Erp, Wilhelmus
  • Van Manen, Jan, Willem
  • Geheniau, Norbert, Johan Lukas

Abstract

Systems, methods, and apparatuses are provided for an advanced gynecological applicator. In accordance with some embodiments, a brachytherapy applicator head and assembly is provided. The assembly may include two ovoid tubes configured to receive radiation sources, the two ovoid tubes combining to form a rounded applicator having a middle opening and comprising a plurality of needle holes to guide interstitial needles. The assembly may also include a central applicator tube configured to receive a radiation source that is located within the middle opening. Additionally, the assembly may include a vaginal cap that includes a tool-free connection to the two ovoid tubes and includes needle guides that align with the needle holes of the two ovoid tubes. The assembly may include a one-piece template for securing interstitial needles. The assembly may further include a tool- free connector to secure the two ovoid tubes to the central applicator tube.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

30.

Mobile X-ray unit

      
Application Number 14971981
Grant Number 09561009
Status In Force
Filing Date 2015-12-16
First Publication Date 2016-04-14
Grant Date 2017-02-07
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Woudstra, Bas
  • De Jager, Wim

Abstract

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The arm may be articuable. The X-ray tube may include a target element configured to generate an X-ray beam and a collimator configured to shape the X-ray beam. The target element may be disposed at a set distance from the collimator.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
  • A61B 6/06 - Diaphragms
  • H05G 1/26 - Measuring, controlling or protecting
  • A61N 5/00 - Radiation therapy

31.

METHODS AND SYSTEMS FOR BRACHYTHERAPY PLANNING BASED ON IMAGING DATA

      
Application Number IB2015001375
Publication Number 2015/181632
Status In Force
Filing Date 2015-05-28
Publication Date 2015-12-03
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van De Wardt, Cor
  • Krechting, Paulus Cornelis, Hendrikus Maria
  • De Becker, Jan Frans, Lodewijk
  • Nesvacil, Nicole
  • Pötter, Richard
  • Schmid, Maximilian, Paul
  • Kirisits, Christian

Abstract

Systems and methods for generating a radiation therapy treatment plan by using ultrasound images are disclosed. The method comprises obtaining a first set of image data representing a first image of an anatomical region that includes a treatment applicator inserted into the anatomical region. The method further comprises receiving tracking information indicating a position of the treatment applicator as represented in the first set of image data, obtaining a second set of image data representing a second image of the anatomical region, and combining at least a portion of the first set of image data with the second set of image data. One of the first set and the second set of image data is used to identify a target tissue portion in the anatomical region. The method further comprises generating, based on the combined image data, treatment plan information for treating the target tissue portion in the anatomical region.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 8/12 - Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
  • A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
  • A61B 8/08 - Clinical applications
  • A61B 8/14 - Echo-tomography
  • A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)

32.

Brachytherapy applicator device for insertion in a body cavity

      
Application Number 14818936
Grant Number 10029119
Status In Force
Filing Date 2015-08-05
First Publication Date 2015-11-26
Grant Date 2018-07-24
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Mäkel, René Gerard Willem
  • Morssink, Pieter
  • Steller, Hendrik
  • Visscher, Arie Luite
  • Van De Wardt, Cor
  • Kuipers, Franciscus Antonius Maria

Abstract

The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

33.

Brachytherapy instrument, an imaging system and a method of image acquisition

      
Application Number 14651541
Grant Number 10226232
Status In Force
Filing Date 2013-12-11
First Publication Date 2015-11-19
Grant Date 2019-03-12
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van De Wardt, Cor
  • Van Erp, Wilhelmus Petra Martinus Maria
  • Visscher, Luite

Abstract

The invention relates to a brachytherapy instrument comprising a body, wherein the body is provided with at least one marker comprising a material suitable to be visualized using an ultrasonic and/or magnetic resonance imaging technique. The invention further relates to an image acquisition system and a method of image acquisition.

IPC Classes  ?

  • A61B 8/00 - Diagnosis using ultrasonic, sonic or infrasonic waves
  • A61B 8/08 - Clinical applications
  • A61B 5/055 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves involving electronic [EMR] or nuclear [NMR] magnetic resonance, e.g. magnetic resonance imaging
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 17/34 - TrocarsPuncturing needles
  • A61B 90/96 - Identification means for patients or instruments, e.g. tags coded with symbols, e.g. text using barcodes
  • A61B 34/20 - Surgical navigation systemsDevices for tracking or guiding surgical instruments, e.g. for frameless stereotaxis
  • A61B 90/00 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges

34.

Methods of making a medical applicator

      
Application Number 14437305
Grant Number 09662511
Status In Force
Filing Date 2013-10-25
First Publication Date 2015-09-24
Grant Date 2017-05-30
Owner Nucletron Operations B.V. (Netherlands)
Inventor Krechting, Paulus Cornelis Hendrikus Maria

Abstract

Embodiments of the disclosure are drawn to methods of forming an applicator body of an applicator for insertion into an anatomical cavity of a patient for delivering a treatment to the patient. In some instances, the method may include receiving a first three-dimensional image of the anatomical cavity, which was generated while the anatomical cavity contained an expandable container adjacent a tissue region of the patient, and while the expandable container was filled with fluid such that the container was expanded to substantially conform to the shape of at least a portion of the tissue region. The method also may include isolating, from the first three-dimensional image, a first sub-image corresponding to an image of the filled expanded container. The method further may include using the first sub-image as a design template for forming the applicator body for use with the patient.

IPC Classes  ?

  • B29C 41/02 - Shaping by coating a mould, core or other substrate, i.e. by depositing material and stripping-off the shaped articleApparatus therefor for making articles of definite length, i.e. discrete articles
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • B29C 33/38 - Moulds or coresDetails thereof or accessories therefor characterised by the material or the manufacturing process
  • B29C 67/00 - Shaping techniques not covered by groups , or
  • B33Y 10/00 - Processes of additive manufacturing
  • B33Y 80/00 - Products made by additive manufacturing
  • B29L 31/00 - Other particular articles
  • A61B 34/10 - Computer-aided planning, simulation or modelling of surgical operations

35.

Mobile X-ray unit

      
Application Number 14697761
Grant Number 09259596
Status In Force
Filing Date 2015-04-28
First Publication Date 2015-08-13
Grant Date 2016-02-16
Owner NUCLETRON OPERATIONS, B.V. (Netherlands)
Inventor Jager, Wim De

Abstract

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base and an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The X-ray tube may be configured to generate an X-ray beam. The X-ray applicator may include an exit surface through which the X-ray beam passes in use. The X-ray unit may further include an applicator cap for covering at least the exit surface of the X-ray applicator.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

36.

Afterloading device, and use thereof

      
Application Number 14283470
Grant Number 09795804
Status In Force
Filing Date 2014-05-21
First Publication Date 2014-11-27
Grant Date 2017-10-24
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van Appeldoorn, Adriaan
  • Schuurman, Jeroen
  • Van Beek, Martin
  • Sollen, Finn
  • Henning, Johan
  • Visscher, Arie Luite

Abstract

An afterloading device for effectuating a brachytherapy treatment, comprising a first elongated flexible transport element, arranged to maneuver a radiation source between a storage position inside the afterloading device and a treatment position outside the afterloading device, the afterloading device further comprising a second elongated flexible transport element, having at least one transducer, the second transport element being arranged to move the at least one transducer between a first transducer position and a second transducer position.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • G01T 1/02 - Dosimeters

37.

Mobile X-ray unit

      
Application Number 14454882
Grant Number 09724066
Status In Force
Filing Date 2014-08-08
First Publication Date 2014-11-27
Grant Date 2017-08-08
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abstract

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include an X-ray applicator for emitting an X-ray beam for irradiating an object. The mobile X-ray unit may further include a phantom-based dosimetry system configured to perform a dosimetry check of the X-ray beam. The phantom-based dosimetry system may include two sets of dose meters, each set being positioned on a surface at a distinct depth. The mobile X-ray unit may also include a dosimetry control unit configured to receive measurements from the two sets of dose meters and determine whether the dosimetry check is passed based on the measurements.

IPC Classes  ?

  • A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • G01T 1/02 - Dosimeters
  • A61B 5/107 - Measuring physical dimensions, e.g. size of the entire body or parts thereof

38.

Brachy Academy

      
Application Number 1219106
Status Registered
Filing Date 2014-03-05
Registration Date 2014-03-05
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ?
  • 41 - Education, entertainment, sporting and cultural services
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Education services; educational programs and workshops; e-learning. Medical services, namely providing medical information by the internet.

39.

Brachytherapy source assembly

      
Application Number 14122853
Grant Number 10166403
Status In Force
Filing Date 2012-06-01
First Publication Date 2014-07-03
Grant Date 2019-01-01
Owner Nuvletron Operations B.V. (Netherlands)
Inventor
  • Bakker, Pier
  • De Jager, Wim
  • Visscher, Arie Luite
  • Vreeken, Henk

Abstract

An embodiment of the present disclosure is directed to a brachytherapy source assembly including a guiding wire and a brachytherapy capsule located at a distal end of the guiding wire. The capsule includes a chamber defined by a wall for holding a radioactive source. At least a portion of an exterior surface of the wall of the capsule includes at least one of a friction-reducing coating, a wear-resistant coating, and a wear-indication coating a coating.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

40.

A BRACHYTHERAPY INSTRUMENT, AN IMAGING SYSTEM AND A METHOD OF IMAGE ACQUISITION

      
Application Number NL2013050889
Publication Number 2014/092570
Status In Force
Filing Date 2013-12-11
Publication Date 2014-06-19
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van De Wardt, Cor
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Visscher, Luite

Abstract

The invention relates to a brachytherapy instrument comprising a body, wherein the body is provided with at least one marker comprising a material suitable to be visualized using an ultrasonic and/or magnetic resonance imaging technique. The invention further relates to an image acquisition system and a method of image acquisition.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)

41.

A GAMMA SOURCE TRACKING SYSTEM

      
Application Number IB2013003078
Publication Number 2014/068405
Status In Force
Filing Date 2013-10-23
Publication Date 2014-05-08
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Krechting, Paulus Cornelis, Hendrikus Maria

Abstract

Embodiments of the disclosure relate to a method for reconstructing a spatial position of a conduit arranged to accommodate a radiotherapeutic radioactive source, The method includes displacing an object emitting radiation inside the conduit prior to the administration of a treatment, detecting said radiation using detectors; generating data upon detecting the said radiation using a processor; and reconstructing the spatial position of the conduit by the processor based on the said data to identify a delivery path of the treatment.

IPC Classes  ?

  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

42.

A MEDICAL APPLICATOR AND METHODS OF MAKING

      
Application Number IB2013002634
Publication Number 2014/068398
Status In Force
Filing Date 2013-10-25
Publication Date 2014-05-08
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Krechting, Paulus Cornelis, Hendrikus Maria

Abstract

Embodiments of the present disclosure are directed to forming an applicator for insertion into an anatomica! cavity of a patient for delivering a treatment to the patient The method may include receiving a three-dimensionai image of the anatomical cavity, wherein the three-dimensional image is generated while the anatomical cavity contains an expandable container adjacent a tissue region of the patient. The container may be expanded when contained in the anatomical cavity to substantially conform to the shape of at least a portion of the tissue region forming at least a portion of the anatomical cavity. The method may further include isolating, from the three-dimensional image, a first sub-image corresponding to an image of the filled expanded container and using the sub-image as a design template for forming the applicator for use with the patient.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

43.

AN ESOPHAGUS APPLICATOR FOR BRACHYTHERAPY

      
Application Number NL2013050755
Publication Number 2014/069991
Status In Force
Filing Date 2013-10-28
Publication Date 2014-05-08
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van Der Zanden, Maarten Antonius Christiaan
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Van De Wardt, Cor

Abstract

The invention relates to an esophagus applicator for brachy therapy, comprising a molded plastic body comprising a proximal portion and a distal portion, said body accommodating a plurality of conduits, wherein at least one conduit from the said plurality of conduits is adapted to accommodate a displaceable radioactive source, and a further conduit from the said plurality of conduits is arranged to accommodate a guidewire, said proximal portion being connectable to an after loader device, said distal portion being substantially cone-shaped.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61M 25/09 - Guide wires

44.

A MODULAR APPLICATOR FOR BRACHYTHERAPY

      
Application Number NL2013050750
Publication Number 2014/065667
Status In Force
Filing Date 2013-10-25
Publication Date 2014-05-01
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Martens, Tommy Robert Oscar
  • Van Wijck, Gaetan Stephan Marie
  • Van De Wardt, Cor

Abstract

A modular applicator (10) for enabling a brachytherapy treatment comprising a central element (1a, 1b) and one or more of peripheral elements, wherein the central element is adapted with a fixation mechanism having a core (4) for affixing the said peripheral elements thereto, wherein the fixation mechanism prevents a rotational displacement of the peripheral elements attached to the core (4) of the fixation element with respect to the central element (1a, 1b).

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

45.

Modular applicator for brachytherapy

      
Application Number 14063408
Grant Number 09737729
Status In Force
Filing Date 2013-10-25
First Publication Date 2014-05-01
Grant Date 2017-08-22
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Martens, Tommy Robert Oscar
  • Van Wijck, Gaetan Stephan Marie
  • Van De Wardt, Cor

Abstract

Embodiments of the present disclosure relate to a modular applicator for enabling a brachytherapy treatment, comprising a central core and an outer sleeve, wherein the central core is adapted with a fixation mechanism for affixing the outer sleeve to the central core, wherein the outer sleeve is manufactured from a substantially rigid or shapeable material.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

46.

Modular applicator for brachytherapy

      
Application Number 14063527
Grant Number 09827443
Status In Force
Filing Date 2013-10-25
First Publication Date 2014-05-01
Grant Date 2017-11-28
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Martens, Tommy Robert Oscar
  • Van Wijck, Gaetan Stephan Marie
  • Van De Wardt, Cor

Abstract

A modular applicator for enabling a brachytherapy treatment comprising a central element and one or more of peripheral elements, wherein the central element is adapted with a fixation mechanism having a core for affixing the said peripheral elements thereto, wherein the fixation mechanism prevents a rotational displacement of the peripheral elements attached to the core of the fixation element with respect to the central element.

IPC Classes  ?

  • A61N 5/00 - Radiation therapy
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61M 25/02 - Holding devices, e.g. on the body

47.

A MODULAR APPLICATOR FOR BRACHYTHERAPY

      
Application Number NL2013050749
Publication Number 2014/065666
Status In Force
Filing Date 2013-10-25
Publication Date 2014-05-01
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van Erp, Wilhelmus Petrus Martinus Maria
  • Martens, Tommy Robert Oscar
  • Van Wijck, Gaetan Stephan Marie
  • Van De Wardt, Cor

Abstract

The invention relates to a modular applicator (15) for enabling a brachytherapy treatment, comprising a central core (8) and an outer sleeve (9), wherein the central core is adapted with a fixation mechanism (8a) for affixing the outer sleeve to the central core, wherein the outer sleeve is manufactured from a substantially rigid or shapeable material.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

48.

LUMENCARE

      
Serial Number 86216056
Status Registered
Filing Date 2014-03-10
Registration Date 2015-06-02
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy

49.

BRACHY ACADEMY

      
Serial Number 79153325
Status Registered
Filing Date 2014-03-05
Registration Date 2015-08-11
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ?
  • 41 - Education, entertainment, sporting and cultural services
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Educational services, namely, conducting educational programs, workshops, e-learning sessions and webcasts in the field of internal radiotherapy Medical services, namely, providing medical information by the internet

50.

Luneray

      
Application Number 1182413
Status Registered
Filing Date 2013-09-18
Registration Date 2013-09-18
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, medical apparatus for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use, namely, pre-assembled sterile needle-catheter combinations for interstitial brachytherapy treatments.

51.

Luneray

      
Application Number 164404900
Status Registered
Filing Date 2013-09-18
Registration Date 2019-07-11
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

(1) Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, catheters for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use, namely, pre-assembled sterile needle-catheter combinations for interstitial brachytherapy treatments.

52.

LUNERAY

      
Serial Number 79138745
Status Registered
Filing Date 2013-09-18
Registration Date 2014-05-06
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, medical apparatus for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use, namely, pre-assembled sterile needle-catheter combinations for interstitial brachytherapy treatments

53.

Brachy Academy

      
Application Number 012131471
Status Registered
Filing Date 2013-09-11
Registration Date 2014-02-05
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ?
  • 41 - Education, entertainment, sporting and cultural services
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Education services; educational programs and workshops; e-learning and webcasts. Medical services, namely providing medical information by the internet.

54.

Brachytherapy applicator device for insertion in a body cavity

      
Application Number 13807552
Grant Number 09132282
Status In Force
Filing Date 2011-06-30
First Publication Date 2013-08-08
Grant Date 2015-09-15
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Mäkel, René Gerard Willem
  • Morssink, Pieter
  • Steller, Hendrik
  • Visscher, Arie Luite
  • Van De Wardt, Cor
  • Kuipers, Franciscus Antonius Maria

Abstract

The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

55.

Apparatus and methods for radiation treatment of tissue surfaces

      
Application Number 13765339
Grant Number 08675815
Status In Force
Filing Date 2013-02-12
First Publication Date 2013-06-20
Grant Date 2014-03-18
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Holt, Randall W.
  • Axelrod, Steve
  • Burnside, Robert R.
  • Neimeyer, Robert G.
  • Rusch, Tom

Abstract

A device, system and method for administering radiation therapy to a tissue surface of a patient utilizes an applicator capable of controlled movement and repositioning over a selected area of tissue, under the control of a computer or controller. A servo-controlled manipulator can effect a raster scan of the desired area, such as an area of the skin, and this can be in any desired pattern such as serpentine, spiral, parallel but unidirectional, or irregular patterns. Preferably a third direction of control is included, i.e. a depth direction, with an appropriate form of depth sensor, a signal from which can be used to adjust the radiation source so that radiation of the tissue surface is consistent over varied contoured.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

56.

LumenCare Azure

      
Application Number 011669397
Status Registered
Filing Date 2013-03-19
Registration Date 2013-08-14
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, medical apparatus for surgical interventions and applications; treatment delivery positioning accessories, namely catheters for intraluminal brachytherapy treatments.

57.

Luneray

      
Application Number 011669322
Status Registered
Filing Date 2013-03-19
Registration Date 2013-08-14
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical apparatus and instruments for use in the field of cancer diagnostics, treatment and brachytherapy, namely, medical apparatus for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use, namely, pre-assembled sterile needle-catheter combinations for interstitial brachytherapy treatments.

58.

Applicators and methods for intraoperative treatment of proliferative diseases of the breast

      
Application Number 13649257
Grant Number 08529427
Status In Force
Filing Date 2012-10-11
First Publication Date 2013-02-07
Grant Date 2013-09-10
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Francescatti, Darius
  • Jervis, James E.

Abstract

A device for administering brachytherapy to a patient includes a vessel that may be in the form of a hollow cylindrical cup, for fleshing into and substantially filling the open-ended cavity. The vessel has a closed outer end, which may be a removable cover, and a source guide penetrates the closed outer end so as to extend deep into the vessel, to receive a radiation source in the source guide. A manipulator can be connected to the radiation source, and also to the source guide, for allowing several different types of manipulation of the source orientation and position within the vessel during the brachytherapy procedure.

IPC Classes  ?

  • A61N 5/01 - Devices for producing movement of radiation source during therapy

59.

A GAMMA SOURCE TRACKING SYSTEM

      
Application Number NL2012050518
Publication Number 2013/012331
Status In Force
Filing Date 2012-07-19
Publication Date 2013-01-24
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Henning, Johan
  • Woudstra, Bas
  • Schuurman, Jeroen

Abstract

The invention relates to a radioactive source tracking system adapted to determine in real time a spatial position of a gamma source (la, lb) in a volume, comprising a set of spatially distributed position sensitive detectors (PSD) (5) operable in real time arranged about the volume, a real time computer system adapted to calculate the spatial position per time stamp of the gamma source in the said volume based on respective signals generated by said PSD's, wherein the radioactive source is represented by a 3D or 4D data stream in real time. The invention further relates to a method for tracking a radioactive gamma source and a computer program product for causing a processor to determine a real time 3D or a 4D spatial position of a gamma source.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • G01T 1/178 - Circuit arrangements not adapted to a particular type of detector for measuring specific activity in the presence of other radioactive substances, e.g. natural, in the air or in liquids such as rain-water

60.

Lightweight radiation absorbing shield

      
Application Number 12800083
Grant Number 08354658
Status In Force
Filing Date 2010-05-06
First Publication Date 2013-01-15
Grant Date 2013-01-15
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Smith, Peter C.
  • Axelrod, Steve
  • Lovoi, Paul A.

Abstract

A flexible, lightweight radiation absorbing sheet or shield includes heavy metal particles in one layer and mid-atomic number particles in another layer, the layer that will be adjacent to the patient. The shield is particularly intended for protection of the wearer and others from radiation emanating from a therapeutic source positioned within the patient's body. With the disclosed multi-layer shield construction, backscattered radiation off the heavy metal particle layer, affecting the patient's adjacent tissue, is minimized.

IPC Classes  ?

61.

BRACHYTHERAPY SOURCE ASSEMBLY

      
Application Number NL2012050386
Publication Number 2012/165964
Status In Force
Filing Date 2012-06-01
Publication Date 2012-12-06
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Bakker, Pier
  • De Jager, Wim
  • Visscher, Arie Luite
  • Vreeken, Henk

Abstract

The invention is directed to a brachytherapy source assembly, to a kit of parts, to a method for preparing a brachytherapy source assembly, to uses of a specific coating, and to a brachytherapy treatment. The brachytherapy source assembly of the invention comprises a push/pull wire and at the distal end thereof a capsule suitable for brachytherapy, wherein said capsule comprises a chamber for holding one or more radioactive sources, said chamber being defined by a wall, and wherein at least part of the exterior surface of the wall of the capsule comprises a coating, the coating comprising one or more selected from TiN, TiCN, TiCrN, CrN, TiA1CrN, DLC, and MοS2, wherein said capsule is attached to the push/pull wire or wherein said capsule is comprised in the push/pull wire.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

62.

ELECTRONIC BRACHYTHERAPY SYSTEM

      
Serial Number 85780989
Status Registered
Filing Date 2012-11-16
Registration Date 2013-07-09
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

RADIATION THERAPY APPARATUS, NAMELY A MINIATURE ELECTRONIC X-RAY TUBE, A BALLOON APPLICATOR AND CATHETER FOR RECEIVING THE MINIATURE X-RAY TUBE TO ADMINISTER RADIATION TO A PATIENT, AN ELECTRONIC CONTROLLER FOR THE X-RAY TUBE AND FOR THE BALLOON APPLICATOR, AND A FLEXIBLE XRAY SHIELD FOR USE ON A PATIENT TO CONTAIN RADIATION

63.

ESTEYA

      
Application Number 1124478
Status Registered
Filing Date 2012-05-21
Registration Date 2012-05-21
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical products, especially for skin cancer. Surgical and medical devices and instruments and diagnosis devices, especially for skin cancer. Medical services, especially related to skin cancer.

64.

Mobile X-ray unit

      
Application Number 13335414
Grant Number 08520801
Status In Force
Filing Date 2011-12-22
First Publication Date 2012-06-28
Grant Date 2013-08-27
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Henning, Johan

Abstract

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit, a power supply, and a cooler. The mobile X-ray unit further including an articulated arm associated with the base and coupled to an X-ray applicator. The X-ray applicator including an X-ray tube having an anode for generating an acceleration field and a target element for generating an X-ray beam, wherein a longitudinal axis of the anode is substantially parallel to a longitudinal axis of the X-ray tube.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

65.

A MOBILE X-RAY UNIT

      
Application Number NL2011050870
Publication Number 2012/087126
Status In Force
Filing Date 2011-12-21
Publication Date 2012-06-28
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Henning, Johan

Abstract

The invention relates to a mobile X-ray unit(10) comprising a base (2) for accommodating a control unit, a power supply and a cooler and further comprising an articulated displaceable arm (4a) supporting an X-ray applicator (4) comprising an X-ray tube having a longitudinal axis, said X-ray applicator being connected to the base, the X-ray tube comprising an anode for generating an acceleration field and a target for generating an X-ray beam, the anode being disposed substantially parallel to the longitudinal axis of the X-ray tube. The invention further relates to a method of manufacturing a mobile X-ray tube and a method of delivering an X-ray beam.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

66.

A MOBILE X-RAY UNIT

      
Application Number NL2011050872
Publication Number 2012/087127
Status In Force
Filing Date 2011-12-21
Publication Date 2012-06-28
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Woudstra, Bas
  • De Jager, Wim

Abstract

The invention relates to a mobile X-ray unit (10) comprising a base(2) for accommodating a control unit, a power supply and a cooler and further comprising an articulated displaceable arm (4a) supporting an X-ray applicator (4) provided with an X-ray tube, said X-ray applicator being connected to the base, the X-ray tube comprising a target for generating an X-ray beam and a collimator for shaping the generated X-ray beam, a distance between the target and the collimator being in the range between 4 and 10 cm.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

67.

A MOBILE X-RAY UNIT

      
Application Number NL2011050880
Publication Number 2012/087133
Status In Force
Filing Date 2011-12-21
Publication Date 2012-06-28
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Henning, Johan
  • Woudstra, Bas

Abstract

The invention relates to a mobile X-ray unit (10) comprising a base(2) for accommodating a control unit and a power supply further comprising an articulated displaceable arm (4a) supporting an X-ray applicator(4) having an X-ray tube, said X-ray applicator being connected to the base using a flexible cable (3), wherein the X-ray tube comprises a target for generating an X-ray beam (8a), a collimator for shaping the generated X- ray beam and an exit surface (8) through which the X-ray beam passes in use, wherein the X-ray unit further comprises an indicator for providing a visual indication of at least a portion of the X-ray beam emitted from the exit surface.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

68.

Mobile X-ray unit

      
Application Number 13335712
Grant Number 08995616
Status In Force
Filing Date 2011-12-22
First Publication Date 2012-06-28
Grant Date 2015-03-31
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abstract

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit for controlling an X-ray applicator and a power supply for supplying power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base and coupled to the X-ray applicator. The X-ray applicator may have an X-ray tube configured to emit an X-ray beam through an exit window to irradiate an object. The mobile X-ray unit may further include a dosimetry system adapted for real time dosimetry.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • H05G 1/28 - Measuring or recording actual exposure timeCounting number of exposuresMeasuring required exposure time
  • A61N 5/00 - Radiation therapy
  • H01J 35/00 - X-ray tubes

69.

Mobile X-ray unit

      
Application Number 13335830
Grant Number 08929511
Status In Force
Filing Date 2011-12-22
First Publication Date 2012-06-28
Grant Date 2015-01-06
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abstract

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base for accommodating a control unit configured to control an X-ray applicator and a power supply configured to supply power to the X-ray applicator. The mobile X-ray unit may further include an articulated arm associated with the base. The arm may be configured to support the X-ray applicator. The X-ray applicator may have an X-ray tube for emitting an X-ray beam for irradiating an object. The mobile X-ray unit may further include a phantom-based dosimetry system configured to perform a dosimetry check of the X-ray beam.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • H05G 1/28 - Measuring or recording actual exposure timeCounting number of exposuresMeasuring required exposure time
  • A61B 6/00 - Apparatus or devices for radiation diagnosisApparatus or devices for radiation diagnosis combined with radiation therapy equipment

70.

Mobile X-ray unit

      
Application Number 13335863
Grant Number 09036787
Status In Force
Filing Date 2011-12-22
First Publication Date 2012-06-28
Grant Date 2015-05-19
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor De Jager, Wim

Abstract

One embodiment of the present disclosure is directed to a mobile X-ray unit. The mobile X-ray unit may include a base and an arm associated with the base. The arm may be configured to support an X-ray applicator having an X-ray tube. The X-ray tube may be configured to generate an X-ray beam. The X-ray applicator may include an exit surface through which the X-ray beam passes in use. The X-ray unit may further include an applicator cap for covering at least the exit surface of the X-ray applicator.

IPC Classes  ?

  • H01J 5/18 - Windows permeable to X-rays, gamma-rays, or particles
  • H01J 35/16 - VesselsContainersShields associated therewith
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • H05G 1/04 - Mounting the X-ray tube within a closed housing

71.

Method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as well as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body

      
Application Number 13411132
Grant Number 09364685
Status In Force
Filing Date 2012-03-02
First Publication Date 2012-06-28
Grant Date 2016-06-14
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Kindlein, Johann

Abstract

The invention relates to a method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as wells as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body. C comparing said reconstructed location said pre-planned plurality of locations. Furthermore the system according to the invention is characterized in that identifying means are present for identifying the location of at least one treatment channel from said group of said plurality of inserted treatment channels and comparing said identified location with one or more of said pre-planned locations present in said treatment plan.

IPC Classes  ?

  • A61B 5/05 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)

72.

A MOBILE X-RAY UNIT

      
Application Number NL2011050875
Publication Number 2012/087129
Status In Force
Filing Date 2011-12-21
Publication Date 2012-06-28
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Verhaar, Thamar Jacinthe Sarah
  • Van Schaik, Sander-Willem
  • Hekkenberg, Sebastiaan Willem

Abstract

The invention relates to a mobile X-ray unit comprising a base (2), a mast (5) cooperating with the base and an articulated arm (4a), mechanically coupled to the mast and supporting an X-ray applicator (4) provided with an X-ray tube, the mast (5) being displaceable with respect the base (2) in an upward direction, the articulated arm (4a) comprising a ball joint (6b) at one end and a rotational joint (6a) at another end for adjusting a spatial position of the X-ray applicator (4) in use.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

73.

A MOBILE X-RAY UNIT

      
Application Number NL2011050877
Publication Number 2012/087130
Status In Force
Filing Date 2011-12-21
Publication Date 2012-06-28
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor De Jager, Wim

Abstract

The invention relates to a mobile X-ray unit (10) comprising a base (2) for accommodating a control unit and a power supply, further comprising an articulated displaceable arm (4a) supporting an X-ray applicator (4) provided with an X-ray tube, the X-ray applicator comprising an exit surface through which the X-ray beam passes in use and an applicator cap for covering at least the exit surface.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

74.

A MOBILE X-RAY UNIT

      
Application Number NL2011050878
Publication Number 2012/087131
Status In Force
Filing Date 2011-12-21
Publication Date 2012-06-28
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abstract

The invention relates to a mobile X-ray unit comprising a base (2) for accommodating a control unit and a power supply further comprising an articulated displaceable arm (4a) supporting an X-ray applicator (4) having an X-ray tube for emitting an X-ray beam (8a) through an exit window (8) for irradiating an object, wherein the X-ray unit further comprises a phantom- based dosimetry system (9a, 9b, 9c) adapted to perform the on-line or real-time dosimetry check of the X-ray beam.

IPC Classes  ?

75.

A MOBILE X-RAY UNIT

      
Application Number NL2011050879
Publication Number 2012/087132
Status In Force
Filing Date 2011-12-21
Publication Date 2012-06-28
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van Der Veen, Johannes Simon
  • Woudstra, Bas
  • Henning, Johan

Abstract

The invention relates to a mobile X-ray unit (10) comprising a base(2) for accommodating a control unit and a power supply further comprising an articulated displaceable arm (4a) supporting an X-ray applicator(4) having an X-ray tube for emitting an X-ray beam (8a) through an exit window (8) for irradiating an object, the X-ray unit further comprises a built-in dosimetry system (9) adapted to carry out the on-line or real time dosimetry.

IPC Classes  ?

  • A61N 5/00 - Radiation therapy
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • H05G 1/44 - Exposure time using arrangements for switching when a predetermined dose of radiation has been applied, e.g. in which the switching instant is determined by measuring the electrical energy supplied to the tube in which the switching instant is determined by measuring the amount of radiation directly

76.

ESTEYA

      
Serial Number 79116060
Status Registered
Filing Date 2012-05-21
Registration Date 2013-07-16
Owner Nucletron Operations B.V. (Netherlands)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

[ Pharmaceutical preparations for treatment of skin cancer ] [ Surgical and ] medical devices [ and instruments and diagnosis devices ] used in the treatment of skin cancer, namely, medical x-ray [ apparatus and medical ] radiation [ apparatus to deliver x-ray radiation for surface ] * treatment apparatus for skin * brachytherapy procedures [ Medical services, especially related to skin cancer ]

77.

Proportional attenuation of radiation in brachytheraphy treatment

      
Application Number 13291854
Grant Number 09055972
Status In Force
Filing Date 2011-11-08
First Publication Date 2012-03-01
Grant Date 2015-06-16
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Axelrod, Steve
  • Burnside, Robert R.
  • Lovoi, Paul A.

Abstract

Attenuating masks for selective attenuation of radiation, particularly from an x-ray source in brachytherapy, employ materials having atomic number in a specific range, so as to attenuate radiation dose intensity generally proportionally through a range of distance from the source. Some preferred attenuation materials are silver and molybdenum. A set of small masks can be provided for a particular design of catheter that holds a radiation source, each mask having a size and shape to define a different solid angle of masking, so that in a brachytherapy procedure, sensitive tissue such as bone or skin can be protected by proper selection of and positioning of the attenuating mask, to reduce the dose intensity to that tissue.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61B 19/00 - Instruments, implements or accessories for surgery or diagnosis not covered by any of the groups A61B 1/00-A61B 18/00, e.g. for stereotaxis, sterile operation, luxation treatment, wound edge protectors(protective face masks A41D 13/11; surgeons' or patients' gowns or dresses A41D 13/12; devices for carrying-off, for treatment of, or for carrying-over, body liquids A61M 1/00)

78.

Components and assembly for performing brachytherapy treatment of tumour tissue in a human and animal body

      
Application Number 13262629
Grant Number 09623261
Status In Force
Filing Date 2010-03-22
First Publication Date 2012-02-02
Grant Date 2017-04-18
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Van De Wardt, Cor
  • Buijs, Emil Matthijs
  • Visscher, Arie Luite

Abstract

The invention relates to an assembly for performing brachytherapy treatment of tumor tissue in a human or animal body comprising an intracavitary component and at least one guiding unit, said at least one guiding unit exhibiting a longitudinal axis and being connectable to said intracavitary component, and wherein said at least one guiding unit is provided with coupling means for coupling at least one interstitial needle-assembly for delivering treatment to said tumor tissue. The assembly has coupling/uncoupling means arranged to allow a displacement of said at least one interstitial needle-assembly in a direction transverse to said longitudinal axis and to prevent a displacement of said at least one interstitial needle-assembly in a direction parallel to or a pre-defined angle to said longitudinal axis. This coupling principle allows for the preparation of the guiding unit before the patient is being hospitalized and positioned in the treatment room and will prevent the unwanted uncoupling of the interstitial needle-assembly during the actual treatment being performed, further reducing the risk of adversely affected treatment parameters (location and duration of the radiation being administered to the patient).

IPC Classes  ?

  • A61M 36/10 - Utero-vaginal or pelvic application
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61M 25/01 - Introducing, guiding, advancing, emplacing or holding catheters
  • A61M 37/00 - Other apparatus for introducing media into the bodyPercutany, i.e. introducing medicines into the body by diffusion through the skin
  • A61B 90/11 - Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups , e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
  • A61B 17/42 - Gynaecological or obstetrical instruments or methods
  • A61B 17/34 - TrocarsPuncturing needles

79.

BRACHYTHERAPY APPLICATOR DEVICE FOR INSERTION IN A BODY CAVITY

      
Application Number NL2011050474
Publication Number 2012/002815
Status In Force
Filing Date 2011-06-30
Publication Date 2012-01-05
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Mäkel, René Gerard Willem
  • Morssink, Pieter
  • Steller, Hendrik
  • Visscher, Arie Luite
  • Van De Wardt, Cor
  • Kuipers, Franciscus Antonius Maria

Abstract

The invention relates to a brachytherapy applicator device for insertion in a body cavity. The applicator device comprises an applicator shaped for insertion in the body cavity; the applicator comprising connectable segments; at least one connectable part having a form following wall surface shaped to follow the body cavity, the wall surface having a multichannel groove structure, so as to guide a plurality of catheters along the grooves in the groove structure along the wall surface.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

80.

Apparatus and methods for radiation treatment of tissue surfaces

      
Application Number 12802744
Grant Number 08374313
Status In Force
Filing Date 2010-06-11
First Publication Date 2011-12-15
Grant Date 2013-02-12
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Holt, Randall W.
  • Axelrod, Steve
  • Burnside, Robert
  • Neimeyer, Robert G.
  • Rusch, Thomas W.

Abstract

A device, system and method for administering radiation therapy to a tissue surface of a patient utilizes an applicator capable of controlled movement and repositioning over a selected area of tissue, under the control of a computer or controller. A servo-controlled manipulator can effect a raster scan of the desired area, such as an area of the skin, and this can be in any desired pattern such as serpentine, spiral, parallel but unidirectional, or irregular patterns. Preferably a third direction of control is included, i.e. a depth direction, with an appropriate form of depth sensor, a signal from which can be used to adjust the radiation source so that radiation of the tissue surface is consistent over varied contoured.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • H05G 1/02 - Constructional details

81.

Assembly for performing brachytherapy treatment of a tumour tissue in an animal body

      
Application Number 13120282
Grant Number 08834339
Status In Force
Filing Date 2009-09-23
First Publication Date 2011-09-15
Grant Date 2014-09-16
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Hannoun-Levi, Jean-Michel
  • Van De Wardt, Cor
  • Visscher, Arie Luite
  • Binnekamp, Dirk

Abstract

This invention relates to an assembly for performing brachytherapy treatment of tumour tissue in an animal body comprising at least a longitudinally extending intracavitary component and at least a guiding unit which extends at least partly parallel to said intracavitary component. Said guiding unit comprises at least one interstitial needle for guiding a radiation source into the tumour tissue. Said guiding unit is tubular over at least a longitudinal distance sufficient that in use a proximal end of said guiding unit is situated outside said body to be treated, while a distal end of said guiding unit is situated in situ close to or adjacent the tumour tissue.

IPC Classes  ?

  • A61N 5/00 - Radiation therapy
  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy

82.

EBX

      
Serial Number 85081466
Status Registered
Filing Date 2010-07-09
Registration Date 2012-04-10
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

RADIATION THERAPY APPARATUS, namely, A MINIATURE ELECTRONIC X-RAY TUBE, A BALLOON APPLICATOR AND CATHETER FOR RECEIVING THE MINIATURE X-RAY TUBE TO ADMINISTER RADIATION TO A PATIENT, AN ELECTRONIC CONTROLLER FOR THE X-RAY TUBE AND FOR THE BALLOON APPLICATOR, AND A FLEXIBLE X-RAY SHIELD FOR USE ON A PATIENT TO CONTAIN RADIATION, ALL SOLD AS A UNIT

83.

Applicators and methods for intraoperative treatment of proliferative diseases of the breast

      
Application Number 12156298
Grant Number 08303476
Status In Force
Filing Date 2008-05-30
First Publication Date 2009-12-03
Grant Date 2012-11-06
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Francescatti, Darius
  • Jervis, James E.

Abstract

A device for administering brachytherapy to a patient includes a vessel that may be in the form of a hollow cylindrical cup, for fleshing into and substantially filling the open-ended cavity. The vessel has a closed outer end, which may be a removable cover, and a source guide penetrates the closed outer end so as to extend deep into the vessel, to receive a radiation source in the source guide. A manipulator can be connected to the radiation source, and also to the source guide, for allowing several different types of manipulation of the source orientation and position within the vessel during the brachytherapy procedure.

IPC Classes  ?

  • A61N 5/01 - Devices for producing movement of radiation source during therapy

84.

Proportional attenuation of radiation in brachytherapy treatment

      
Application Number 12072620
Grant Number 08062203
Status In Force
Filing Date 2008-02-26
First Publication Date 2009-08-27
Grant Date 2011-11-22
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Axelrod, Steve
  • Burnside, Robert R.
  • Lovoi, Paul A.

Abstract

Attenuating masks for selective attenuation of radiation, particularly from an x-ray source in brachytherapy, employ materials having atomic number in a specific range, so as to attenuate radiation dose intensity generally proportionally through a range of distance from the source. Some preferred attenuation materials are silver and molybdenum. A set of small masks can be provided for a particular design of catheter that holds a radiation source, each mask having a size and shape to define a different solid angle of masking, so that in a brachytherapy procedure, sensitive tissue such as bone or skin can be protected by proper selection of and positioning of the attenuating mask, to reduce the dose intensity to that tissue.

IPC Classes  ?

85.

Balloon brachytherapy applicator and method

      
Application Number 11871116
Grant Number 07727137
Status In Force
Filing Date 2007-10-11
First Publication Date 2009-08-20
Grant Date 2010-06-01
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Francescatti, Darius
  • Hoffmann, David J.
  • Tremberth, Scott
  • Klein, Michael
  • Lovoi, Paul A.
  • Jervis, James E.

Abstract

Methods and applicator apparatus are disclosed for brachytherapy treatment of tissue surrounding a cavity in a patient, particularly a resection cavity. In treatment regimes requiring recovery time between successive radiation treatments, applicators of the invention are retained under the skin, with the skin allowed to at least partially heal, and are re-accessed later for one or more subsequent treatments. To reduce patient discomfort an anesthetic agent can be infused through the applicator to patient tissue, for insertion, balloon inflation or removal of the applicator.

IPC Classes  ?

  • A61M 36/00 - Applying radioactive material to the body
  • A61M 36/04 - Arrangements specially adapted for placing, e.g. inhaling or injecting, radioactive material within the body
  • A61N 5/00 - Radiation therapy

86.

IPSA

      
Application Number 1007099
Status Registered
Filing Date 2009-05-11
Registration Date 2009-05-11
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Scientific apparatus and instruments for use in the field of cancer diagnostics and treatment and brachytherapy, including image guided brachytherapy and adaptive brachytherapy; apparatus and instruments in the form of computer hardware and computer software for use in radio oncology; brachytherapy treatment systems comprised of medical software and hardware for use in performing intraluminal, interstitial and intraoperative procedures and outpatient treatment and medical computer software and apparatus for imaging and real time imaging; brachytherapy apparatus using ionising radiation for scientific purposes and not for medical use. Medical apparatus and instruments for use in the field of cancer diagnostics and treatment and brachytherapy, including image guided brachytherapy and adaptive brachytherapy, afterloaders, applicators, needles, catheters and templates, all for use in radio oncology, cancer and brachytherapy treatment; medical apparatus for surgical interventions and applications; brachytherapy apparatus using ionising radiation for medical use; bio-absorbable materials for medical and surgical use, including implantable radiation therapy devices consisting of radioactive seeds and a bio-absorbable carrier assembly; permanent implants of artificial materials; medical disposables, including disposable syringes and applicators; nanomaterials and nano sources for medical use, namely a delivery system comprising a device that produces nanomaterials and nano sources to diagnose or treat cancer. Design, development, programming and updating of computer hardware and computer software in the medical field; installation, maintenance and repair of computer software in the medical field; scientific and technological services, namely research and design services.

87.

Brachytherapy apparatus and method for use with minimally invasive surgeries of the lung

      
Application Number 11978147
Grant Number 08409070
Status In Force
Filing Date 2007-10-26
First Publication Date 2009-04-30
Grant Date 2013-04-02
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Carol, Mark P.
  • Jervis, James E.
  • Lovoi, Paul A.

Abstract

Brachytherapy treatment of a patient's lung tissue following resection is effected using a balloon applicator which is inserted, normally through the same opening used for the surgery, through the chest wall and into the cavity. The lung and chest openings are closed around the applicator and generally sealed around the applicator. A suction port is provided, in a suction circuit of the applicator, to withdraw fluid from the pleural cavity, at intervals as needed, to assure that the lung can be inflated. Different embodiments of suction circuits are disclosed. A bronchial applicator and method are also disclosed.

IPC Classes  ?

88.

Customized gynecological brachytherapy applicator and method

      
Application Number 11809836
Grant Number 07678040
Status In Force
Filing Date 2007-05-31
First Publication Date 2008-12-04
Grant Date 2010-03-16
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Francescatti, Darius
  • Lovoi, Paul A.

Abstract

A customized gynecological brachytherapy applicator is formed by placing a molded balloon, which is secured to a handle, into a vaginal cavity and then filling the mold balloon with a settable liquid material. The material may be an expanding foam or any other form of curable material that becomes solid, rigid or pliable, when set by chemical action, temperature change, oxidation, a curing means such as a light, or other curing regime. The mold balloon can be elastic or inelastic, depending on the degree to which the applicator is to conform its external surfaces to the vaginal contours. One or more lumina are provided in the set filler material to receive a radiation source, with additional lumina optionally provided for purposes such as drainage or administration of therapeutic agents. The applicator may be withdrawn and reinserted into the vagina during treatment, and selected tissues adjacent to the applicator are irradiated in accordance with a radiation prescription.

IPC Classes  ?

89.

Customized gynecological brachytherapy applicator and method

      
Application Number 11805065
Grant Number 07744521
Status In Force
Filing Date 2007-05-21
First Publication Date 2008-11-27
Grant Date 2010-06-29
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Francescatti, Darius
  • Lovoi, Paul A.

Abstract

A customized gynecological brachytherapy applicator is formed by placing a molded balloon, which is secured to a handle, into a vaginal cavity and then filling the mold balloon with a settable liquid material. The material may be an expanding foam or any other form of curable material that becomes solid, rigid or pliable, when set by chemical action, temperature change, oxidation, a curing means such as a light, or other curing regime. The mold balloon can be elastic or inelastic, depending on the degree to which the applicator is to conform its external surfaces to the vaginal contours. One or more lumina are provided in the set filler material to receive a radiation source, with additional lumina optionally provided for purposes such as drainage or administration of therapeutic agents. The applicator may be withdrawn and reinserted into the vagina during treatment, and selected tissues adjacent to the applicator are irradiated in accordance with a radiation prescription.

IPC Classes  ?

90.

Apparatus for introducing catheters or needles into a body part

      
Application Number 11564733
Grant Number 08162884
Status In Force
Filing Date 2006-11-29
First Publication Date 2008-10-23
Grant Date 2012-04-24
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Van'T Hooft, Eric

Abstract

A template, to be provided at some distance from the skin, provided with multiple guide holes for needles or catheters of which one or more can anchor in the prostate. The template is provided with a locking mechanism so that, after placement, the anchored needles keep all needles in their original places. The above-described method of fixedly positioning a treatment template prevents the needles from moving due to swelling of the tissue in the prostate, which causes the irradiation source, which is later provided in the needles, to improperly irradiate the area.

IPC Classes  ?

  • A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
  • A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles

91.

Method for adaptive radiation treatment of breast tissue surrounding a cancer resection cavity of arbitrary shape

      
Application Number 11932974
Grant Number 08262555
Status In Force
Filing Date 2007-10-31
First Publication Date 2008-06-26
Grant Date 2012-09-11
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Jervis, James E.
  • Lovoi, Paul A.

Abstract

Radiation treatment methods for breast cancer following resection, both intraoperative and post operative, involve mapping preferably using an electronic x-ray source, and can include rotation of a direction source. By using a very rapid, near-instantaneous method of pathology of tissue margins following resection, the invention carries out intraoperative radiation treatment, preferably with the patient remaining anesthetized. Whether or not radiation is intraoperative, the invention preferably includes a mapping procedure using an electronic source that is progressed through the resection cavity while radiation dose is sensed at one or more points, to determine the shape of the resection cavity.

IPC Classes  ?

92.

Transport cable and source capsule with safe connecting construction for internally irradiating patients

      
Application Number 11876419
Grant Number 10933255
Status In Force
Filing Date 2007-10-22
First Publication Date 2008-05-22
Grant Date 2021-03-02
Owner Nucletron Operations B.V. (Netherlands)
Inventor
  • Van'T Hooft, Eric
  • Van Zwol, Libbe

Abstract

A source guide apparatus for brachytherapy application, wherein the source guide apparatus is provided with a source capsule, a guidewire for moving the source capsule through a catheter, a mechanical connection between the guidewire and the source capsule, wherein the source guide apparatus is provided with a sleeve which is attached on the capsule, wherein the sleeve envelops at least a part of the mechanical connection.

IPC Classes  ?

  • A61N 5/10 - X-ray therapyGamma-ray therapyParticle-irradiation therapy
  • A61M 36/04 - Arrangements specially adapted for placing, e.g. inhaling or injecting, radioactive material within the body

93.

Radiation therapy apparatus with selective shielding capability

      
Application Number 11471277
Grant Number 07686755
Status In Force
Filing Date 2006-06-19
First Publication Date 2008-01-10
Grant Date 2010-03-30
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Smith, Peter C.
  • Klein, Michael
  • Hausen, Heike
  • Lovoi, Paul A.

Abstract

Brachytherapy applicators incorporate various forms of selective shielding devices for controlling the direction and intensity of radiation directed at a patient's tissue. In some forms the applicators include a retractable sheath, in some a series of retractable fingers. In other forms the applicator, having an inflatable balloon, has a shield which is retractable from a position adjacent to the balloon or retracted from the balloon, or a shield can itself be inflatable, separately or together with the balloon.

IPC Classes  ?

94.

Endoscopic/percutaneous electronic radiation applicator and method of use

      
Application Number 11481242
Grant Number 07914434
Status In Force
Filing Date 2006-07-03
First Publication Date 2008-01-03
Grant Date 2011-03-29
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Francescatti, Darius
  • Lovoi, Paul A.

Abstract

Treatment of lesions in any luminal or organ system of mammalian anatomy is performed using an electronic source of ionizing radiation and aided by an endoscopic or percutaneous approach.

IPC Classes  ?

95.

Gynecological instrument

      
Application Number 11746983
Grant Number 07871365
Status In Force
Filing Date 2007-05-10
First Publication Date 2007-11-29
Grant Date 2011-01-18
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Van'T Hooft, Eric

Abstract

An apparatus is described for irradiating cervical cancer, comprising multiple source guide tubes with a coupling piece situated outside the patient that connects the tubes outside the patient. The source guide tubes are formed such that the portions of the tubes situated in the patient upon insertion hook to each other so that the tubes are locked relative to each other. In an embodiment, the apparatus further comprises a central catheter tube to be guided into the uterus, which is provided with a flange-shaped stop for stabilizing the central tube relative to the uterus, the stop being formed for securing a position of the central tube relative to the further source guide tubes.

IPC Classes  ?

96.

Method for locating a source in a body

      
Application Number 11744515
Grant Number 08033980
Status In Force
Filing Date 2007-05-04
First Publication Date 2007-11-22
Grant Date 2011-10-11
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Van'T Hooft, Eric

Abstract

The invention relates to a source guide apparatus for guiding and locating a radiation source in a human body, wherein a catheter is provided in a body and connected to the apparatus, and wherein the proximal end is kept in a predetermined position with respect to the body. According to the invention, a treatment window is set, which is situated within the body, within which the source can be kept in respective positions, wherein the treatment window has a fixed window width and a reference position situated at a predetermined distance with respect to the proximal end of the catheter. The source guide apparatus guides the source through the catheter to a predetermined position in the body, measured relative to the treatment window.

IPC Classes  ?

97.

FLEXISHIELD

      
Serial Number 77267570
Status Registered
Filing Date 2007-08-29
Registration Date 2008-05-13
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

RADIATION BARRIER TO BE PLACED AGAINST THE EXTERIOR OF A PATIENT FOR BRACHYTHERAPY PROCEDURES

98.

MicroSelectron

      
Application Number 924299
Status Registered
Filing Date 2006-12-12
Registration Date 2006-12-12
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
NICE Classes  ?
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 37 - Construction and mining; installation and repair services
  • 41 - Education, entertainment, sporting and cultural services
  • 42 - Scientific, technological and industrial services, research and design

Goods & Services

Scientific apparatus and instruments, including scientific apparatus and instruments in the field of cancer and brachytherapy, including image guided brachytherapy and adaptive brachytherapy; computer hardware and computer software in the medical field, including computer hardware and computer software for use in radio-oncology; brachytherapy treatment systems (being medical software or hardware) as well as medical computer software and apparatus for imaging and real time imaging; non medical electronic apparatus (as far as not included in other classes) for use in cancer therapy; x-ray brachytherapy apparatus (not for medical use) for scientific purposes. Medical apparatus and instruments, including medical apparatus and instruments in the field of cancer and brachytherapy, including image guided brachytherapy and adaptive brachytherapy, afterloaders, applicators, needles and templates, all for use in radio-oncology, cancer and brachytherapy treatment; medical apparatus for microsurgery interventions and applications; x-ray brachytherapy apparatus (for medical use); bioabsorbable materials for medical and surgical use, permanent implants (of artificial materials), medical disposables, nanomaterials and nanosources for medical use. Installation, maintenance and repair of computer hardware in the medical field. Education, training and organizing of congresses, workshops, courses, seminars and user meetings (also in-house) in the field of radiation therapy. Design, development, programming and updating of computer hardware and computer software in the medical field; installation, maintenance and repair of computer software in the medical field; scientific and technological services as well as accompanying research and design services.

99.

Method for identifying the location of at least one treatment channel that is one of a plurality of treatment channels, as well as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body

      
Application Number 11187941
Grant Number 08145290
Status In Force
Filing Date 2005-07-25
First Publication Date 2007-04-05
Grant Date 2012-03-27
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor Kindlein, Johann

Abstract

The invention relates to a method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as wells as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body. C comparing said reconstructed location said pre-planned plurality of locations. Furthermore the system according to the invention is characterized in that identifying means are present for identifying the location of at least one treatment channel from said group of said plurality of inserted treatment channels and comparing said identified location with one or more of said pre-planned locations present in said treatment plan.

IPC Classes  ?

  • A61B 5/05 - Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fieldsMeasuring using microwaves or radio waves

100.

Apparatus and method for effecting radiation treatment on a pre-selected anatomical portion of an animal body

      
Application Number 11487303
Grant Number 08133166
Status In Force
Filing Date 2006-07-17
First Publication Date 2007-02-15
Grant Date 2012-03-13
Owner NUCLETRON OPERATIONS B.V. (Netherlands)
Inventor
  • Kindlein, Johann
  • Visscher, Arie
  • Henning, Johan
  • Engels, Wouter Peter

Abstract

The invention relates to an apparatus for effecting radiation treatment on a pre-selected anatomical portion of an animal body comprising: a group of n hollow treatment channels being inserted at one or more pre-planned positions in said pre-selected anatomical portion; a group of m delivery channels to be connected to a corresponding number m from said group of n hollow treatment channels with m being 2 or more and n being 1 or more; identifying means for identifying which one of said m delivery channels is being connected with which one of said n hollow treatment channels, said identifying means comprising a tracking element accommodated in a tracking channel, said tracking element being intended to be displaced from said tracking channel through each of said interconnected m delivery channels and m treatment channels; storage means for storing k energy emitting sources in a corresponding source-channel, with k≦m; delivery means for temporarily inserting said k energy emitting sources from their source-channels through a corresponding one of said interconnected m delivery channels and m treatment channels towards one of said pre-planned positions in said anatomical portion; coupling means for coupling at least one of said m delivery channels with a corresponding treatment channel.

IPC Classes  ?

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