Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subject's hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.
Exemplary embodiments relate to a control circuit for a base station for transmitting energy to a receiver by means of an electric resonant circuit. The control circuit comprises an evaluation device which is designed to compare energy that has been transmitted to a receiver resonant circuit of the receiver with an energy set value. The control circuit is designed to alter the energy input into the receiver resonant circuit of the receiver by altering a resonant frequency of the resonant circuit on the basis of the result of the comparison.
H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H02J 50/80 - Circuit arrangements or systems for wireless supply or distribution of electric power involving the exchange of data, concerning supply or distribution of electric power, between transmitting devices and receiving devices
H02M 3/00 - Conversion of DC power input into DC power output
H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only
H02M 7/48 - Conversion of DC power input into AC power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode
A modular implant device configured for stimulation of at least one nerve or muscle in a body of a subject comprises: a housing; and at least one electrical lead, and/or at least one stimulation electrode; wherein the at least one electrical lead is partly disposed on the housing, and wherein the housing comprises modular elements, the modular elements being arranged in a stack. A system for electrical nerve stimulation comprises a network of at least two modular devices configured for implantation inside a body of a subject according to one of the preceding claims, wherein each modular device is electrically connected to at least one other modular device through electrical leads.
An implantable device configured for implantation in a body of subject. The device includes: a flexible body and at least one stimulator unit attached to the flexible body, wherein the at least one stimulator unit includes a plurality of electric components encapsulated in a hermetically sealed enclosure, a receiving antenna, and at least one electric conductor in electrical connection with the plurality of electric components.
Disclosed herein is an implantable device (10) configured for implantation in a body of subject (50), the device comprising: a flexible body (20) and at least one stimulator unit (30) attached to the flexible body (20), wherein the at least one stimulator unit (30) comprises a plurality of electric components (31) encapsulated in a hermetically sealed enclosure (32), a receiving antenna (33), and at least one electric conductor (34) in electrical connection with the plurality of electric components (31).
The invention described herein refers to a method for measuring a degree of airway opening, e.g. of muscle displacement, to a system for implementing said method as well as to a use of the method and system in obstructive sleep apnea therapy.
The invention described herein refers to a method for measuring a degree of airway opening, e.g. based on an acoustic signal and/or on a muscle displacement, to a system for implementing said method and to a use of the method and system in obstructive sleep apnea therapy.
An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.
A method of treating obstructive sleep apnea according to this disclosure may include: providing an implant comprising a substantially planar central body portion having a top side and a bottom side; at least two adjustable wing portions; and at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion; forming a surgical opening to expose a genioglossus muscle; exposing a branch of a hypoglossal nerve for stimulation by the implant at least on one side of the geniouglossus; forming at least one pocket on at least one side of the geniouglossus; such that the pocket dimensions are configured to fit the at least one of the at least two wing portions of the device; inserting an implant device through the surgical opening such that the central body extends over the genioglossus and each one of the wing portions is received in the respective at least one pocket; and securing the implant device to the muscle.
Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subjects hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.
Disclosed herein is a modular implant device (100) configured for stimulation of at least one nerve or muscle in a body of a subject, the device comprising: a housing (200); and at least one electrical lead (300), and/or at least one stimulation electrode (400); wherein the at least one electrical lead (300) is partly disposed on the housing (200), and wherein the housing (200) comprises modular elements (210), the modular elements (210) being arranged in a stack (211). According to another aspect of this disclosure, a system (900) for electrical nerve stimulation is shown, the system (900) comprising a network of at least two modular devices (100) configured for implantation inside a body of a subject according to one of the preceding claims, wherein each modular device (100) is electrically connected to at least one other modular device (100) through electrical leads (300).
Disclosed herein is a modular implant device (100) configured for stimulation of at least one nerve or muscle in a body of a subject, the device comprising: a housing (200); and at least one electrical lead (300), and/or at least one stimulation electrode (400); wherein the at least one electrical lead (300) is partly disposed on the housing (200), and wherein the housing (200) comprises modular elements (210), the modular elements (210) being arranged in a stack (211). According to another aspect of this disclosure, a system (900) for electrical nerve stimulation is shown, the system (900) comprising a network of at least two modular devices (100) configured for implantation inside a body of a subject according to one of the preceding claims, wherein each modular device (100) is electrically connected to at least one other modular device (100) through electrical leads (300).
Disclosed herein is an implantable device (10) configured for implantation in a body of subject (50), the device comprising: a flexible body (20) and at least one stimulator unit (30) attached to the flexible body (20), wherein the at least one stimulator unit (30) comprises a plurality of electric components (31) encapsulated in a hermetically sealed enclosure (32), a receiving antenna (33), and at least one electric conductor (34) in electrical connection with the plurality of electric components (31).
Disclosed herein is an implantable device (10) configured for implantation in a body of subject (50), the device comprising: a flexible body (20) and at least one stimulator unit (30) attached to the flexible body (20), wherein the at least one stimulator unit (30) comprises a plurality of electric components (31) encapsulated in a hermetically sealed enclosure (32), a receiving antenna (33), and at least one electric conductor (34) in electrical connection with the plurality of electric components (31).
A method of treating obstructive sleep apnea according to this disclosure may include: providing an implant comprising a substantially planar central body portion having a top side and a bottom side; at least two adjustable wing portions; and at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion; forming a surgical opening to expose a genioglossus muscle; exposing a branch of a hypoglossal nerve for stimulation by the implant at least on one side of the geniouglossus; forming at least one pocket on at least one side of the geniouglossus; such that the pocket dimensions are configured to fit the at least one of the at least two wing portions of the device; inserting an implant device through the surgical opening such that the central body extends over the genioglossus and each one of the wing portions is received in the respective at least one pocket; and securing the implant device to the muscle.
An implant unit delivery tool is provided. The implant delivery tool may include a body, a holder disposed at a distal end of the body and adapted to hold an implant unit, and an implant activator associated with the body, the implant activator configured to receive power from a power source. The implant activator may be configured to selectively and wirelessly transfer power from the power source to the implant unit during implantation of the implant unit into the body of a subject to cause modulation of at least one nerve in the body of the subject, and determine a degree of nerve modulation response resulting from the selective and wireless transfer of power from the power source to the implant unit claims.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subject's hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.
Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subject's hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations; sanitary preparations for
medical purposes; transdermal patches for medical purposes
including for use in connection with the field of sleep
apnea and related sleep disorders; adhesive medical patch
including for use in connection with the field of sleep
apnea and related sleep disorders; patch for medical
purposes including in the field of sleep apnea and related
sleep disorders; none of the aforementioned goods for use in
the field of dialysis therapy or blood purification. Data management software for use with medical devices for
the diagnosis and treatment of sleep apnea and related sleep
disorders; computer software for use with medical equipment
for receiving, analyzing, processing, transmitting, and
displaying medical data in the field of sleep disorders;
connection cables and cable connectors for the aforesaid
goods, namely, medical devices for the diagnosis and
treatment of sleep apnea and related sleep disorders;
rechargeable batteries for medical devices; a charging unit
for charging an activation device for activating an
implantable stimulator; downloadable instruction manuals for
medical devices used for the diagnosis and treatment of
sleep apnea and related sleep disorders, and electronic
publications in the nature of instruction manuals for
medical devices used for the diagnoses and treatment of
sleep apnea and related sleep disorders recorded on computer
media related thereto. Medical devices for the diagnosis and treatment of
obstructive sleep apnea and related sleep disorders and
component parts and fittings therefor; electrical
stimulation apparatus for the treatment of obstructive sleep
apnea, namely, an implantable nerve or muscle stimulator
made of artificial materials, disposable patch, and a device
for implanting the stimulator; an activation device for
activating an implantable stimulator, an activation device
for wirelessly activating an implantable stimulator; an
activation device with rechargeable battery for activating
an implantable stimulator; sterile external stimulator for
activating the implantable stimulator; patient screening
kits for the diagnosis of sleep apnea and related sleep
disorders consisting of a medical device for the diagnosis
of obstructive sleep apnea and related sleep disorders, an
electronic data recorder for the recording of information
collected in the diagnosis of obstructive sleep apnea and
related sleep disorders, and data management computer
software for use with medical devices for the diagnosis of
sleep apnea and related sleep disorders, and connection
cables, all sold as a unit, electrical stimulation system
for health and medical purposes and an upper airway
stimulation. Medical services, namely, diagnosis and treatment of
obstructive sleep apnea and related sleep disorders; medical
consultation services in the field of obstructive sleep
apnea and related disorders provided to patients and
doctors; providing medical information in the field of sleep
apnea and related sleep disorders via a website.
A medical device control unit is provided. The control unit may include a communications interface, a memory, and at least one processing device. The processing device may be configured to cause application of a control signal to a primary antenna associated with a unit external to a subject's body. The processing device may further be configured to monitor a feedback signal indicative of the subject's breathing and store, in the memory, information associated with the feedback signal. The processing device may also cause transmission of the stored information, via the communications interface, to a location remote from the control unit. The processing device may further be configured to receive an update signal, from the location remote from the control unit, and cause application of an updated control signal to the primary antenna based on the update signal.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
(1) Pharmaceutical preparations for the treatment of dermatitis, eczema and psoriasis ; disinfectants for medical apparatus and instruments ; transdermal patches for medical purposes namely for use in the treatment of sleep apnea and related sleep disorders, none of the aforementioned goods for use in the field of dialysis therapy or blood purification; adhesive medical patch containing pharmaceutical preparations primarily for use in the treatment of sleep apnea and related sleep disorders, none of the aforementioned goods for use in the field of dialysis therapy or blood purification; transdermal patch for medical purposes namely for use in the treatment of sleep apnea and related sleep disorders, none of the aforementioned goods for use in the field of dialysis therapy or blood purification ;
(2) Data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; Downloadable data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; downloadable computer software for use with medical equipment for receiving, analyzing, processing, transmitting, and displaying medical data in the field of sleep disorders; connection cables and cable connectors for the aforesaid goods, namely, medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; rechargeable batteries for medical devices; a charging unit for charging an activation device for activating an implantable stimulator; downloadable instruction manuals for medical devices used for the diagnosis and treatment of sleep apnea and related sleep disorders, and electronic publications in the nature of instruction manuals for medical devices used for the diagnoses and treatment of sleep apnea and related sleep disorders recorded on computer media related thereto.
(3) Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; Electrical stimulation apparatus for the treatment of obstructive sleep apnea namely an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator, an activation device for activating an implantable stimulator, an activation device for wirelessly activating an implantable stimulator, an activation device with rechargeable battery for activating an implantable stimulator, sterile external stimulator for activating the implantable stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, connection cables all sold as a unit and an electrical stimulation system for health and medical purposes and an upper airway stimulation. (1) Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical information in the field of sleep apnea and related sleep disorders via a website.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations for skin care; sanitary preparations for medical purposes; transdermal patches for medical purposes, namely, for use in the treatment of sleep apnea and related sleep disorders; adhesive medical patch containing pharmaceutical preparations primarily for use in the treatment of sleep apnea and related sleep disorders; transdermal patch for medical purposes, namely, for use in the treatment of sleep apnea and related sleep disorders; none of the aforementioned goods for use in the field of dialysis therapy or blood purification Downloadable data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; downloadable computer software for use with medical equipment for receiving, analyzing, processing, transmitting, and displaying medical data in the field of sleep disorders; connection cables and cable connectors for the aforesaid goods, namely, medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; rechargeable batteries for medical devices; charging appliances for rechargeable equipment, namely, a charging unit for charging an activation device for activating an implantable stimulator; downloadable instruction manuals for medical devices used for the diagnosis and treatment of sleep apnea and related sleep disorders, and electronic publications in the nature of instruction manuals for medical devices used for the diagnoses and treatment of sleep apnea and related sleep disorders recorded on computer media related thereto Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and structural parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; an activation device specially adapted for activating an implantable nerve or muscle stimulator, an activation device specially adapted for wirelessly activating an implantable nerve or muscle stimulator; an activation device with rechargeable battery specially adapted for activating an implantable nerve or muscle stimulator; sterile external nerve or muscle stimulator for activating the implantable nerve or muscle stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables, all sold as a unit; electrical stimulation system for health and medical purposes comprised of electronic nerve and muscle stimulators for upper airway stimulation Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical information in the field of sleep apnea and related sleep disorders via a website
The disclosed subject matter is directed to a surgical implant and a device for its activation. The surgical implant comprises a substantially planar central body portion having a top side and a bottom side and at least two adjustable wing portions. In addition, the implant comprises at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion.
A delivery system is disclosed having an implant retainer configured to releasably hold an implant unit and maintain the implant unit in a fixation location relative to target tissue in a subject's body during an implantation procedure. A first suture guide portion may be disposed on a first side of the implant retainer and configured to guide a suture needle during the implantation procedure. A second suture guide portion may be disposed on a second side of the implant retainer, opposite the first side, and configured to guide the suture needle after the suture needle exits the first suture guide portion.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
H02J 50/05 - Circuit arrangements or systems for wireless supply or distribution of electric power using capacitive coupling
An implant unit delivery tool is provided. The implant delivery tool may include a body, a holder disposed at a distal end of the body and adapted to hold an implant unit, and an implant activator associated with the body, the implant activator configured to receive power from a power source. The implant activator may be configured to selectively and wirelessly transfer power from the power source to the implant unit during implantation of the implant unit into the body of a subject to cause modulation of at least one nerve in the body of the subject, and determine a degree of nerve modulation response resulting from the selective and wireless transfer of power from the power source to the implant unit claims.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61B 5/04 - Measuring bioelectric signals of the body or parts thereof
An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.
A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.
The disclosed subject matter is directed to a surgical implant and a device for its activation. The surgical implant comprises a substantially planar central body portion having a top side and a bottom side and at least two adjustable wing portions. In addition, the implant comprises at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion.
The disclosed subject matter is directed to a surgical implant and a device for its activation. The surgical implant comprises a substantially planar central body portion having a top side and a bottom side and at least two adjustable wing portions. In addition, the implant comprises at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion.
Medical devices for the diagnosis and treatment of
obstructive sleep apnea and related sleep disorders and
component parts and fittings therefor; electrical
stimulation apparatus for the treatment of obstructive sleep
apnea, namely, an implantable nerve or muscle stimulator
made of artificial materials, disposable patch, and a device
for implanting the stimulator; activation device for
activating implantable stimulator, activation device for
wirelessly activating implantable stimulator; activation
device with rechargeable battery for activating implantable
stimulator; sterile external stimulator for activating the
implantable stimulator; patient screening kits for the
diagnosis of sleep apnea and related sleep disorders
consisting of a medical device for the diagnosis of
obstructive sleep apnea and related sleep disorders, an
electronic data recorder for the recording of information
collected in the diagnosis of obstructive sleep apnea and
related sleep disorders, and data management computer
software for use with medical devices for the diagnosis of
sleep apnea and related sleep disorders, and connection
cables, all sold as a unit, electrical stimulation system
for health and medical purposes and an upper airway
stimulation.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical devices for the diagnosis and treatment of
obstructive sleep apnea and related sleep disorders and
component parts and fittings therefor; electrical
stimulation apparatus for the treatment of obstructive sleep
apnea, namely, an implantable nerve or muscle stimulator
made of artificial materials, disposable patch, and a device
for implanting the stimulator; activation device for
activating implantable stimulator, activation device for
wirelessly activating implantable stimulator; activation
device with rechargeable battery for activating implantable
stimulator; sterile external stimulator for activating the
implantable stimulator; patient screening kits for the
diagnosis of sleep apnea and related sleep disorders
consisting of a medical device for the diagnosis of
obstructive sleep apnea and related sleep disorders, an
electronic data recorder for the recording of information
collected in the diagnosis of obstructive sleep apnea and
related sleep disorders, and data management computer
software for use with medical devices for the diagnosis of
sleep apnea and related sleep disorders, and connection
cables, all sold as a unit, electrical stimulation system
for health and medical purposes and an upper airway
stimulation. Medical services, namely, diagnosis and treatment of
obstructive sleep apnea and related sleep disorders; medical
consultation services in the field of obstructive sleep
apnea and related disorders provided to patients and
doctors; providing medical and other related medical
information in the field of sleep apnea and related sleep
disorders via a website.
A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.
Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to be received by and retained by a receiver associated with a housing configured for mounting on the carrier.
A device for the treatment of snoring is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, an interface configured to receive a feedback signal that varies based upon a breathing pattern of the subject; and at least one processing device. The processing device may be configured to analyze the feedback signal and determine whether the subject is snoring based on the analysis of the feedback signal, and if snoring is detected, cause a hypoglossal nerve modulation control signal to be applied to the primary antenna in order to wirelessly transmit the hypoglossal nerve modulation control signal to a secondary antenna associated with an implant unit configured for location in a body of the subject.
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; activation device for activating implantable electrical nerve or muscle stimulator, activation device for wirelessly activating implantable electrical nerve or muscle stimulator; activation device with rechargeable battery for activating implantable electrical nerve or muscle stimulator; sterile external stimulator for activating the implantable electrical nerve or muscle stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected by the medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables for the medical device, all sold as a unit; electrical stimulation system for stimulating upper airway pathways for health and medical purposes Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical and other related health and healthcare information in the field of sleep apnea and related sleep disorders via a website
Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; activation device for activating implantable electrical nerve or muscle stimulator, activation device for wirelessly activating implantable electrical nerve or muscle stimulator; activation device with rechargeable battery for activating implantable electrical nerve or muscle stimulator; sterile external stimulator for activating the implantable electrical nerve or muscle stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected by the medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables for the medical device, all sold as a unit; electrical stimulation system for stimulating upper airway pathways for health and medical purposes
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations; sanitary preparations for
medical purposes; transdermal patches for medical purposes
including for use in connection with the field of sleep
apnea and related sleep disorders; adhesive medical patch
including for use in connection with the field of sleep
apnea and related sleep disorders; patch for medical
purposes including in the field of sleep apnea and related
sleep disorders; none of the aforementioned goods for use in
the field of dialysis therapy or blood purification. Data management software for use with medical devices for
the diagnosis and treatment of sleep apnea and related sleep
disorders; computer software for use with medical equipment
for receiving, analyzing, processing, transmitting, and
displaying medical data in the field of sleep disorders;
connection cables and cable connectors for the aforesaid
goods, namely, medical devices for the diagnosis and
treatment of sleep apnea and related sleep disorders;
rechargeable batteries for medical devices; a charging unit
for charging an activation device for activating an
implantable stimulator; downloadable instruction manuals for
medical devices used for the diagnosis and treatment of
sleep apnea and related sleep disorders, and electronic
publications in the nature of instruction manuals for
medical devices used for the diagnoses and treatment of
sleep apnea and related sleep disorders recorded on computer
media related thereto; electronic data recorder for the
recording of information collected in the diagnosis of
obstructive sleep apnea and related sleep disorders, and
data management computer software for use with medical
devices for the diagnosis of sleep apnea and related sleep
disorders, and connection cables, all sold as a unit. Medical devices for the diagnosis and treatment of
obstructive sleep apnea and related sleep disorders and
component parts and fittings therefor; electrical
stimulation apparatus for the treatment of obstructive sleep
apnea, namely, an implantable nerve or muscle stimulator
made of artificial materials, disposable patch, and a device
for implanting the stimulator; an activation device for
activating an implantable stimulator, an activation device
for wirelessly activating an implantable stimulator; an
activation device with rechargeable battery for activating
an implantable stimulator; sterile external stimulator for
activating the implantable stimulator; patient screening
kits for the diagnosis of sleep apnea and related sleep
disorders consisting of a medical device for the diagnosis
of obstructive sleep apnea and related sleep disorders,
electrical stimulation system for health and medical
purposes and an upper airway stimulation. Medical services, namely, diagnosis and treatment of
obstructive sleep apnea and related sleep disorders; medical
consultation services in the field of obstructive sleep
apnea and related disorders provided to patients and
doctors; providing medical information in the field of sleep
apnea and related sleep disorders via a web site.
A medical device control unit is provided. The control unit may include at least one processing device, a circuit electrically coupled to the at least one processing device, and a flexible housing configured to contain the at least one processing device and the circuit. The flexible housing may include at least one connection portion configured to engage a connector protruding from a flexible carrier, and at least one electrical contact electrically coupled to the circuit and configured to establish an electrical connection with an exposed electrical contact on the flexible carrier when the connection portion is engaged with the at least one connection portion.
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services
Goods & Services
Pharmaceutical preparations for skin care; sanitary preparations for medical purposes; transdermal patches for medical purposes for help with sleep apnea and related sleep disorders; adhesive medical patch for help with sleep apnea and related sleep disorders; patches for medical purposes for help with sleep apnea and related sleep disorders; none of the aforementioned goods for use in the field of dialysis therapy or blood purification Data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; computer software for use with medical equipment for receiving, analyzing, processing, transmitting, and displaying medical data in the field of sleep disorders; connection cables and cable connectors for the aforesaid goods, namely, medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; rechargeable batteries for medical devices; a charging unit for charging an activation device for activating an implantable stimulator; downloadable instruction manuals for medical devices used for the diagnosis and treatment of sleep apnea and related sleep disorders, and electronic publications in the nature of instruction manuals for medical devices used for the diagnoses and treatment of sleep apnea and related sleep disorders recorded on computer media related thereto; electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables, all sold as a unit Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; an activation device for activating an implantable stimulator, an activation device for wirelessly activating an implantable stimulator; an activation device with rechargeable battery for activating an implantable stimulator; sterile external stimulator for activating the implantable stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, electrical stimulation system for health and medical purposes and an upper airway stimulation Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical information in the field of sleep apnea and related sleep disorders via a web site
A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.
A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 5/00 - Measuring for diagnostic purposes Identification of persons
A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
50.
CONTROL CIRCUIT FOR A BASE STATION FOR TRANSMITTING ENERGY TO A RECEIVER BY MEANS OF AN ELECTRIC RESONANT CIRCUIT, EVALUATION DEVICE, METHOD AND COMPUTER PROGRAMME
Exemplary embodiments relate to a control circuit (202) for a base station (204) for transmitting energy to a receiver (206) by means of an electric resonant circuit (208; 300). The control circuit (202) comprises an evaluation device (210) which is designed to compare energy that has been transmitted to a receiver resonant circuit (212) of the receiver (206) with an energy set value. The control circuit (202) is designed to alter the energy input into the receiver resonant circuit (212) of the receiver (206) by altering a resonant frequency of the resonant circuit (208; 300) on the basis of the result of the comparison.
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H02M 3/337 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only in push-pull configuration
H02M 7/48 - Conversion of DC power input into AC power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode
A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
Some embodiments of the disclosure may include a device for wirelessly powering an implant unit in a body of a subject from a location outside of the body of the subject, wherein the implant unit includes a secondary antenna for wirelessly receiving energy. The device may include a primary antenna configured to be located external to the body of the subject, a circuit electrically connected to the primary antenna, and at least one processor electrically connected to the primary antenna and the circuit. The at least one processor may determine a resonant frequency mismatch between a first resonant frequency associated with the primary antenna and a second resonant frequency associated with the secondary antenna associated with the implant unit; and apply an adjustment to at least one component of the circuit to cause a change in the first resonant frequency associated with the primary antenna and a reduction in the resonant frequency mismatch.
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
H02J 50/90 - Circuit arrangements or systems for wireless supply or distribution of electric power involving detection or optimisation of position, e.g. alignment
H02J 50/80 - Circuit arrangements or systems for wireless supply or distribution of electric power involving the exchange of data, concerning supply or distribution of electric power, between transmitting devices and receiving devices
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.
Abstract of the Disclosure A device for controlling operation of a nerve-modulating implant unit from a location external to the body of the subject is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, and at least one processing device. The processing device may be configured to cause generation of a modulation control signal and application of the modulation control signal to the primary antenna in order to wirelessly transmit the modulation control signal to a secondary antenna on the implant unit to cause modulation of at least one nerve using energy transmitted wirelessly from the primary antenna to the secondary antenna, and cause a plurality of predetermined alterations of at least one characteristic of the modulation control signal over successive applications of the modulation control signal during a therapy period. 71 Date recue/Date Received 2021-02-17
A device for controlling operation of a nerve-modulating implant unit from a location external to the body of the subject is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, and at least one processing device. The processing device may be configured to cause generation of a modulation control signal and application of the modulation control signal to the primary antenna in order to wirelessly transmit the modulation control signal to a secondary antenna on the implant unit to cause modulation of at least one nerve using energy transmitted wirelessly from the primary antenna to the secondary antenna, and cause a plurality of predetermined alterations of at least one characteristic of the modulation control signal over successive applications of the modulation control signal during a therapy period.
A neuromodulation device is provided. The neuromodulation device may include a carrier configured for implantation in a subject, the carrier including a first elongated arm and a second elongated arm, each extending from a central portion of the carrier. The device may further include a first pair of modulation electrodes arranged on the first elongated arm, a second pair of modulation electrodes arranged on the second elongated arm. The carrier may be sized and shaped for implantation in a vicinity of a hypoglossal nerve to be modulated such that the first pair of modulation electrodes is located to modulate a first hypoglossal nerve on a first side of the subject and the second pair of modulation electrodes is located to modulate a second hypoglossal nerve on a second side of the subject.
A medical device control unit may include at least one processing device, a circuit electrically coupled to the at least one processing device, and a flexible housing configured to contain the at least one processing device and the circuit. The flexible housing may include at least one connection portion configured to engage a connector protruding from a flexible carrier, and at least one electrical contact electrically coupled to the circuit and configured to establish an electrical connection with an exposed electrical contact on the flexible carrier when the connection portion is engaged with the at least one connection portion.
A unit for wirelessly transmitting power to an implant unit configured to be located in a subject's body is provided. The unit may include a flexible carrier including an adhesive backing configured for attaching the unit to skin of the subject, an antenna associated with the flexible carrier, the antenna being configured to wirelessly transmit power to the implant unit in response to a signal applied to the antenna, and a buffer layer disposed on the flexible carrier at a position to be between the antenna and the skin of the subject when the carrier is attached to the skin of the subject, the buffer layer being configured to establish an air gap between the skin of the subject and the antenna.
An implantable device is provided. The implantable device may include a flexible carrier configured for implantation in a subject, at least one pair of modulation electrodes associated with the carrier, an antenna configured to receive an electrical signal disposed on the flexible carrier, a circuit electrically coupling the antenna to the at least one pair of modulation electrodes; and a ceramic housing. At least one of the antenna and the circuit may be located within the ceramic housing.
A wireless feedback device for monitoring an implant unit configured for location in a body of a subject is provided. The device may include a flexible substrate configured for removable attachment to the subject's skin, a primary antenna disposed on the flexible substrate, an interface configured to receive from the primary antenna a feedback signal based on wireless interaction with a secondary antenna associated with an implant unit configured to be located in the body of the subject, and at least one processing device. The at least one processing device may be configured detect a feedback signal on the primary antenna after cessation of a transmission to the secondary antenna, analyze the feedback signal to determine information relating to a function of the implant unit, and cause at least one response based on the analysis of the feedback signal.
A medical device control unit is provided. The control unit may include a communications interface, a memory, and at least one processing device. The processing device may be configured to cause application of a control signal to a primary antenna associated with a unit external to a subject's body. The processing device may further be configured to monitor a feedback signal indicative of the subject's breathing and store, in the memory, information associated with the feedback signal. The processing device may also cause transmission of the stored information, via the communications interface, to a location remote from the control unit. The processing device may further be configured to receive an update signal, from the location remote from the control unit, and cause application of an updated control signal to the primary antenna based on the update signal.
A device for controlling operation of a nerve-modulating implant unit from a location external to the body of the subject is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, and at least one processing device. The processing device may be configured to cause generation of a modulation control signal and application of the modulation control signal to the primary antenna in order to wirelessly transmit the modulation control signal to a secondary antenna on the implant unit to cause modulation of at least one nerve using energy transmitted wirelessly from the primary antenna to the secondary antenna, and cause a plurality of predetermined alterations of at least one characteristic of the modulation control signal over successive applications of the modulation control signal during a therapy period.
A device for the treatment of snoring is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, an interface configured to receive a feedback signal that varies based upon a breathing pattern of the subject; and at least one processing device. The processing device may be configured to analyze the feedback signal and determine whether the subject is snoring based on the analysis of the feedback signal, and if snoring is detected, cause a hypoglossal nerve modulation control signal to be applied to the primary antenna in order to wirelessly transmit the hypoglossal nerve modulation control signal to a secondary antenna associated with an implant unit configured for location in a body of the subject.
An implant unit configured for implantation into a body of a subject is provided. The implant unit may include an antenna configured to receive a signal, and at least one pair of modulation electrodes configured to be implanted into the body of the subject in the vicinity of at least one nerve to be modulated. The at least one nerve may have a diameter less than about 2 millimeters at a modulation location, and the at least one pair of modulation electrodes may be configured to receive an applied electric signal in response to the signal received by the antenna and generate an electrical field to modulate the at least one nerve from a position spaced apart from the at least one nerve.
An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.
A device for powering an implant within a body of a subject from a location external to the subject, wherein the implant requires a threshold rate of power increase in order to operate in at least one mode, may include an antenna configured to wirelessly transmit energy to the implant. The device may also include a power storage unit configured to store energy from a power source incapable of delivering the threshold rate of power increase to enable the implant unit to operate in the at least one mode and a power release unit configured to release a pulse of energy from the power storage unit to the antenna after the power storage unit collects an amount of energy sufficient to enable the implant unit to operate in the at least one mode.
Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to be received by and retained by a receiver associated with a housing configured for mounting on the carrier.
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
69.
Method for controlling energy delivery as a function of degree of coupling
A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.
A sleep apnea treatment device may include a flexible carrier configured to be implanted in a body of a subject. The device may also include at least one electrode disposed on the flexible carrier, the at least one electrode being configured to modulate nerve fibers of the subject. A flexible antenna may be disposed on the flexible carrier, the flexible antenna electrically connected to the at least one electrode in a manner permitting at least some energy received by the flexible antenna to be transferred to the at least one electrode. The flexible antenna may include: at least a first conductive trace arranged on a first side of the flexible carrier, the at least a first conductive trace defining at least a first elongated space between portions thereof: and at least a second conductive trace arranged on a second side of the flexible carrier, the at least a second conductive trace defining at least a second elongated space between portions thereof, wherein the at least a first conductive trace is at least partially offset from the at least a second conductive trace such that portions of the first conductive trace overly the at least a second elongated space and wherein portions of the second conductive trace underlay the at least a first elongated space.
An implant unit delivery tool is disclosed having an implant tool and an implant activator. The implant tool may be configured to retain an implant unit during an implantation procedure in which the implant unit is fixated to tissue. The implant activator may be associated with the implant tool. Additionally, the implant activator may be configured to selectively transfer power to the implant unit during the implantation procedure to cause modulation of at least one nerve in the body of a subject prior to final fixation of the implant unit to the tissue.
A unit configured for implantation in a subject's body may include a carrier, an implantable circuit associated with the carrier, an antenna arranged on the carrier and configured to wirelessly receive energy from a location external to the subject's body and to provide at least a portion of the energy to the implantable circuit, and at least one component associated with the carrier for receiving energy from the implantable circuit. Wherein the implantable circuit and the antenna have an internal resonant frequency mismatched from an external resonant frequency of an external circuit, to account for resonance frequency variation as a result of implantation in the subject's body.
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A device according to some embodiments may include an implant unit which may include a flexible carrier, an antenna arranged on the flexible carrier, at least one pair of modulation electrodes on the flexible carrier, at least one implantable circuit electrically connected to the at least one pair of modulation electrodes and the antenna; and at least one pair of suture holes passing through the flexible carrier. The at least one pair of suture holes may be arranged on the flexible carrier such that the flexible carrier may be configured to conform to tissue in a subject's body, and such that each suture hole of the at least one pair of suture holes may be positioned to allow suturing to tissue adjacent to the suture holes.
A sleep apnea treatment device may include a flexible carrier configured to be implanted in a body of a subject. The device may also include at least one electrode disposed on the flexible carrier, the at least one electrode being configured to modulate nerve fibers of the subject. A flexible antenna may be disposed on the flexible carrier, the flexible antenna electrically connected to the at least one electrode in a manner permitting at least some energy received by the flexible antenna to be transferred to the at least one electrode. The flexible antenna may include: at least a first conductive trace arranged on a first side of the flexible carrier, the at least a first conductive trace defining at least a first elongated space between portions thereof; and at least a second conductive trace arranged on a second side of the flexible carrier, the at least a second conductive trace defining at least a second elongated space between portions thereof, wherein the at least a first conductive trace is at least partially offset from the at least a second conductive trace such that portions of the first conductive trace overly the at least a second elongated space and wherein portions of the second conductive trace underlay the at least a first elongated space.
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
Some embodiments of the disclosure may include a device for wirelessly powering an implant unit in a body of a subject from a location outside of the body of the subject, wherein the implant unit includes a secondary antenna for wirelessly receiving energy. The device may include a primary antenna configured to be located external to the body of the subject, a circuit electrically connected to the primary antenna, and at least one processor electrically connected to the primary antenna and the circuit. The at least one processor may determine a resonant frequency mismatch between a first resonant frequency associated with the primary antenna and a second resonant frequency associated with the secondary antenna associated with the implant unit; and apply an adjustment to at least one component of the circuit to cause a change in the first resonant frequency associated with the primary antenna and a reduction in the resonant frequency mismatch.
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
A delivery system is disclosed having an implant retainer configured to releasably hold an implant unit and maintain the implant unit in a fixation location relative to target tissue in a subject's body during an implantation procedure. A first suture guide portion may be disposed on a first side of the implant retainer and configured to guide a suture needle during the implantation procedure. A second suture guide portion may be disposed on a second side of the implant retainer, opposite the first side, and configured to guide the suture needle after the suture needle exits the first suture guide portion.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
79.
Therapy protocol activation triggered based on initial coupling
The present disclosure is directed to a control unit for cooperating with an adhesive patch to convey power from a location external to a subject to a location within the subject. The control unit may include a housing configured for selective mounting on the adhesive patch and may further include at least one processor within the housing. The at least one processor may be configured to activate when the housing is mounted on the adhesive patch and to delay, for a predetermined amount of time following activation of the at least one processor, generation of therapeutic control signals for modulating at least one nerve in the subject's body.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61N 1/372 - Arrangements in connection with the implantation of stimulators
H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
H02J 50/05 - Circuit arrangements or systems for wireless supply or distribution of electric power using capacitive coupling
80.
Insert tool for selectively powering an implant unit
An implant unit delivery tool is disclosed having an implant tool and an implant activator. The implant tool may be configured to retain an implant unit during an implantation procedure in which the implant unit is fixated to tissue. The implant activator may be associated with the implant tool. Additionally, the implant activator may be configured to selectively transfer power to the implant unit during the implantation procedure to cause modulation of at least one nerve in the body of a subject prior to final fixation of the implant unit to the tissue.
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
An implant unit may include a substrate and an implantable circuit arranged on the substrate. An encapsulation structure may be disposed over at least a portion of the substrate and at least a portion of the implantable circuit, the encapsulation structure including a parylene layer and a silicon layer disposed over the parylene layer.
A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/372 - Arrangements in connection with the implantation of stimulators
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
The present disclosure is directed to a device. The device includes a flexible carrier and at least one implantable circuit arranged on the flexible carrier. The device further includes at least one meandering electrical trace disposed on the flexible carrier and arranged to establish an electrically conductive path between a first contact point and a second contact point associated with the at least one implantable circuit. The at least one meandering electrical trace is configured to maintain the electrically conductive path during flexing of the flexible carrier.
A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A medical device may be configured to transmit energy from a position outside of a subject's body to a position inside the subject's body. The device may include a flexible substrate having a thickness of between 5 and 100 micrometers and a flexible antenna comprising between 10 and 15 windings on a first surface of the flexible substrate, the antenna having a transmission frequency of between 6.4 to 8.3 MHz, and wherein the antenna is configured to transmit energy to a penetration depth of at least 1 cm into the subject's body. The device may also include an adhesive disposed on at least one surface of the flexible substrate for adhering to skin of the subject.
A61N 1/372 - Arrangements in connection with the implantation of stimulators
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
A61N 1/375 - Constructional arrangements, e.g. casings
84.
SYSTEM AND METHOD FOR NERVE MODULATION USING NONCONTACTING ELECTRODES
An implant unit configured for implantation into a body of a subject may include an antenna configured to receive a signal. The implant unit may also include at least one pair of modulation electrodes configured to be implanted into the body of the subject in the vicinity of at least one nerve to be modulated, the at least one pair of modulation electrodes being configured to receive an applied electric signal in response to the signal received by the antenna and generate an electrical field to modulate the at least one nerve from a position where the at least one pair of modulation electrodes does not contact the at least one nerve.
A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.
A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub- modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.
A device according to some embodiments may include a primary antenna configured to be located external to a subject. The device may also include at least one processor in electrical communication with the primary antenna and configured to receive a condition signal from an implantable device, the condition signal indicative of a precursor to sleep disordered breathing, and cause transmission of a primary signal from the primary antenna to the implantable device, in response to the condition signal, to stimulate at least one nerve in response to the precursor to sleep disordered breathing.
A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.
An implant unit according to some embodiments may include a flexible carrier, at least one pair of modulation electrodes on the flexible carrier, and at least one implantable circuit in electrical communication with the at least one pair of modulation electrodes. The at least one pair of modulation electrodes and the at least one circuit may be configured for implantation through derma on an underside of a subject's chin and for location proximate to terminal fibers of the medial branch of the subject's hypoglossaS nerve, such that an electric field extending from the at least one pair of modulation electrodes can modulate one or more of the terminal fibers of the medial branch of the hypoglossal nerve.
A device according to some embodiments may include an implantable flexible carrier and a pair of electrodes located on the carrier. The electrodes may be spaced from each other by a distance greater than 3 mm, and may be configured to cause, when supplied with an electrical signal, a unidirectional electric field sufficient to modulate at least one nerve.
A device is disclosed that includes an external unit configured to communicate with an implant unit beneath the skin of a subject and an indicator associated with the external unit. The indicator is configured to produce an indicator signal when the external unit is within a predetermined range of the implant unit. In addition, the indicator may be configured to vary the indicator signal according to a distance between the external unit and the implant unit. Furthermore, a method of locating an external unit with respect to an implant unit is disclosed that includes detecting a distance between the external unit and the implanted unit located beneath the skin of a subject, producing an indicator signal when the external unit is within a predetermined range of the implant unit, and varying the indicator signal as a function of a distance between the external unit and the implant unit.
Devices and methods are disclosed that include an external unit comprising at least one processor. The processor may be configured to receive a signal indicative of tongue movement in a subject from an implant unit implanted in the subject, determine whether the tongue movement is representative of sleep disordered breathing, generate a modulation control signal to correct the sleep disordered breathing when the at least one processor determines an occurrence of sleep disordered breathing.
A device may include at least one pair of modulation electrodes configured for implantation in the vicinity of a nerve to be modulated such that the electrodes are spaced apart from one another along a longitudinal direction of the nerve to be modulated. The electrodes may be further configured to facilitate an electric field in response to an applied electric signal, the electric field including field lines extending in the longitudinal direction of the nerve to be modulated. The device may further include at least one circuit in electrical communication with the at least one pair of modulation electrodes and being configured to cause application of the electric signal applied at the at least one pair of modulation electrodes.
A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.
An implant unit configured for implantation into a body of a subject may include an antenna configured to receive a signal. The implant unit may also include at least one pair of modulation electrodes configured to be implanted into the body of the subject in the vicinity of at least one nerve to be modulated, the at least one pair of modulation electrodes being configured to receive an applied electric signal in response to the signal received by the antenna and generate an electrical field to modulate the at least one nerve from a position where the at least one pair of modulation electrodes does not contact the at least one nerve.
A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.
A device for delivering energy as a function of degree coupling may include an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The device may further include a primary antenna associated with the at least one processor. The processor may be configured to determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
A device according to some embodiments may include a housing configured for location external to a body of a subject The device may also include at least one processor associated with the housing and configured to communicate with a circuit implanted in the subject within proximity to a tongue of the subject, wherein the circuit is in electrical communication with at least one electrode, receive a physiological signal from the subject via the circuit, and send a control signal to the implanted circuit in response to the physiological signal, wherein the control signal is predetermined to activate neuromuscular tissue within the tongue.
A device for delivering energy as a function of degree coupling may include an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The device may further include a primary antenna associated with the at least one processor. The processor may be configured to determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.
A device for delivering energy as a function of degree coupling may include an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The device may further include a primary antenna associated with the at least one processor. The processor may be configured to determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.