Nyxoah SA

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A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers 76
A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode 75
A61N 1/372 - Arrangements in connection with the implantation of stimulators 61
A61N 1/378 - Electrical supply 54
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10 - Medical apparatus and instruments 15
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1.

METHOD AND SYSTEM FOR ELECTRICAL NERVE STIMULATION

      
Application Number 18746503
Status Pending
Filing Date 2024-06-18
First Publication Date 2024-10-10
Owner Nyxoah SA (Belgium)
Inventor Tsukran, Roi Moshe

Abstract

Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subject's hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

2.

MEDICAL IMPLANT SYSTEM INCLUDING BASE STATION AND MEDICAL IMPLANT

      
Application Number 18647050
Status Pending
Filing Date 2024-04-26
First Publication Date 2024-08-15
Owner NYXOAH S.A. (Belgium)
Inventor
  • Müeller, Carsten
  • Koch, Timo

Abstract

Exemplary embodiments relate to a control circuit for a base station for transmitting energy to a receiver by means of an electric resonant circuit. The control circuit comprises an evaluation device which is designed to compare energy that has been transmitted to a receiver resonant circuit of the receiver with an energy set value. The control circuit is designed to alter the energy input into the receiver resonant circuit of the receiver by altering a resonant frequency of the resonant circuit on the basis of the result of the comparison.

IPC Classes  ?

  • H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
  • A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopesIlluminating arrangements therefor
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/378 - Electrical supply
  • H02J 50/80 - Circuit arrangements or systems for wireless supply or distribution of electric power involving the exchange of data, concerning supply or distribution of electric power, between transmitting devices and receiving devices
  • H02M 1/00 - Details of apparatus for conversion
  • H02M 3/00 - Conversion of DC power input into DC power output
  • H02M 3/335 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only
  • H02M 7/48 - Conversion of DC power input into AC power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode
  • H03J 3/02 - Continuous tuning Details

3.

STACK DESIGN IMPLANT DEVICE

      
Application Number 18253261
Status Pending
Filing Date 2020-11-18
First Publication Date 2024-01-25
Owner Nyxoah SA (Belgium)
Inventor
  • Van Den Heuvel, Koen Erik
  • Vermeiren, Jan
  • Bervoets, Wim
  • Svehla, Martin Joseph
  • Raje, Milind Chandrakant
  • Meeusen, Tom

Abstract

A modular implant device configured for stimulation of at least one nerve or muscle in a body of a subject comprises: a housing; and at least one electrical lead, and/or at least one stimulation electrode; wherein the at least one electrical lead is partly disposed on the housing, and wherein the housing comprises modular elements, the modular elements being arranged in a stack. A system for electrical nerve stimulation comprises a network of at least two modular devices configured for implantation inside a body of a subject according to one of the preceding claims, wherein each modular device is electrically connected to at least one other modular device through electrical leads.

IPC Classes  ?

  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/04 - Electrodes

4.

PAIR OF INTELLIGENT ELECTRIC CONDUCTORS

      
Application Number 18465225
Status Pending
Filing Date 2023-09-12
First Publication Date 2024-01-04
Owner Nyxoah SA (Belgium)
Inventor
  • Vossenberg, Marcel
  • Bervoets, Wim
  • Raje, Milind Chandrakant
  • Van Den Heuvel, Koen Erik

Abstract

An implantable device configured for implantation in a body of subject. The device includes: a flexible body and at least one stimulator unit attached to the flexible body, wherein the at least one stimulator unit includes a plurality of electric components encapsulated in a hermetically sealed enclosure, a receiving antenna, and at least one electric conductor in electrical connection with the plurality of electric components.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/378 - Electrical supply
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

5.

PAIR OF INTELLIGENT ELECTRIC CONDUCTORS

      
Application Number 18245445
Status Pending
Filing Date 2020-09-18
First Publication Date 2023-11-09
Owner Nyxoah SA (Belgium)
Inventor
  • Vossenberg, Marcel
  • Bervoets, Wim
  • Raje, Milind Chandrakant
  • Van Den Heuvel, Koen Erik

Abstract

Disclosed herein is an implantable device (10) configured for implantation in a body of subject (50), the device comprising: a flexible body (20) and at least one stimulator unit (30) attached to the flexible body (20), wherein the at least one stimulator unit (30) comprises a plurality of electric components (31) encapsulated in a hermetically sealed enclosure (32), a receiving antenna (33), and at least one electric conductor (34) in electrical connection with the plurality of electric components (31).

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply

6.

METHOD AND SYSTEM FOR MEASURING A DEGREE OF MUSCLE DISPLACEMENT AND USE OF THE METHOD AND SYSTEM IN TREATING OBSTRUCTIVE SLEEP APNEA

      
Application Number EP2023055447
Publication Number 2023/169955
Status In Force
Filing Date 2023-03-03
Publication Date 2023-09-14
Owner NYXOAH SA (Belgium)

Abstract

The invention described herein refers to a method for measuring a degree of airway opening, e.g. of muscle displacement, to a system for implementing said method as well as to a use of the method and system in obstructive sleep apnea therapy.

IPC Classes  ?

  • A61B 5/08 - Measuring devices for evaluating the respiratory organs
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/0538 - Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter

7.

METHOD AND SYSTEM FOR SENSING A SUBJECT'S BREATHING AND USE OF THE METHOD AND SYSTEM IN TREATING OBSTRUCTIVE SLEEP APNEA

      
Application Number EP2023055448
Publication Number 2023/169956
Status In Force
Filing Date 2023-03-03
Publication Date 2023-09-14
Owner NYXOAH SA (Belgium)

Abstract

The invention described herein refers to a method for measuring a degree of airway opening, e.g. based on an acoustic signal and/or on a muscle displacement, to a system for implementing said method and to a use of the method and system in obstructive sleep apnea therapy.

IPC Classes  ?

  • A61B 5/08 - Measuring devices for evaluating the respiratory organs
  • A61B 5/087 - Measuring breath flow
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/0538 - Measuring electrical impedance or conductance of a portion of the body invasively, e.g. using a catheter

8.

Patch

      
Application Number 29706981
Grant Number D0988519
Status In Force
Filing Date 2019-09-25
First Publication Date 2023-06-06
Grant Date 2023-06-06
Owner NYXOAH S.A. (Belgium)
Inventor
  • Yosef, Yoel Ben
  • Adimor, Ronen
  • Tsukran, Roi Moshe

9.

Arced implant unit for modulation of nerves

      
Application Number 16940557
Grant Number 11857791
Status In Force
Filing Date 2020-07-28
First Publication Date 2023-04-27
Grant Date 2024-01-02
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61B 5/389 - Electromyography [EMG]
  • A61B 5/08 - Measuring devices for evaluating the respiratory organs
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

10.

METHOD FOR QUANTIFICATION OF A LEVEL OF RESPONSE TO HYPOGLOSSAL NERVE STIMULATION AND METHOD OF PREDICTING

      
Document Number 03225223
Status Pending
Filing Date 2022-07-12
Open to Public Date 2023-01-19
Owner NYXOAH SA (Belgium)
Inventor
  • Kohn, Sarah
  • Katzir, Doron
  • Tsukran, Roi
  • Toberman, Daniel
  • Lichtenstadt, Assaf
  • Nelson, Dwight

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/08 - Measuring devices for evaluating the respiratory organs

11.

METHOD FOR QUANTIFICATION OF A LEVEL OF RESPONSE TO HYPOGLOSSAL NERVE STIMULATION AND METHOD OF PREDICTING

      
Application Number EP2022069421
Publication Number 2023/285441
Status In Force
Filing Date 2022-07-12
Publication Date 2023-01-19
Owner NYXOAH SA (Belgium)

IPC Classes  ?

  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/08 - Measuring devices for evaluating the respiratory organs

12.

Method and Process for Placement and Fixation of a Surgical Implant

      
Application Number 17636227
Status Pending
Filing Date 2020-08-26
First Publication Date 2022-10-27
Owner Nyxoah SA (Belgium)
Inventor
  • Ron, Udi
  • Gianello, Pierre
  • Lewis, Richard
  • Bertolus, Chloe

Abstract

A method of treating obstructive sleep apnea according to this disclosure may include: providing an implant comprising a substantially planar central body portion having a top side and a bottom side; at least two adjustable wing portions; and at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion; forming a surgical opening to expose a genioglossus muscle; exposing a branch of a hypoglossal nerve for stimulation by the implant at least on one side of the geniouglossus; forming at least one pocket on at least one side of the geniouglossus; such that the pocket dimensions are configured to fit the at least one of the at least two wing portions of the device; inserting an implant device through the surgical opening such that the central body extends over the genioglossus and each one of the wing portions is received in the respective at least one pocket; and securing the implant device to the muscle.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers

13.

METHOD AND SYSTEM FOR ELECTRICAL NERVE STIMULATION

      
Application Number 17612417
Status Pending
Filing Date 2020-05-18
First Publication Date 2022-06-30
Owner Nyxoah SA (Belgium)
Inventor Tskuran, Roi Moshe

Abstract

Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subjects hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

14.

STACK DESIGN IMPLANT DEVICE

      
Application Number EP2020082564
Publication Number 2022/105996
Status In Force
Filing Date 2020-11-18
Publication Date 2022-05-27
Owner NYXOAH SA (Belgium)

Abstract

Disclosed herein is a modular implant device (100) configured for stimulation of at least one nerve or muscle in a body of a subject, the device comprising: a housing (200); and at least one electrical lead (300), and/or at least one stimulation electrode (400); wherein the at least one electrical lead (300) is partly disposed on the housing (200), and wherein the housing (200) comprises modular elements (210), the modular elements (210) being arranged in a stack (211). According to another aspect of this disclosure, a system (900) for electrical nerve stimulation is shown, the system (900) comprising a network of at least two modular devices (100) configured for implantation inside a body of a subject according to one of the preceding claims, wherein each modular device (100) is electrically connected to at least one other modular device (100) through electrical leads (300).

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

15.

STACK DESIGN IMPLANT DEVICE

      
Document Number 03201458
Status Pending
Filing Date 2020-11-18
Open to Public Date 2022-05-27
Owner NYXOAH SA (Belgium)
Inventor
  • Van Den Heuvel, Koen Erik
  • Vermeiren, Jan
  • Bervoets, Wim
  • Svehla, Martin Joseph
  • Raje, Milind Chandrakant
  • Meeusen, Tom

Abstract

Disclosed herein is a modular implant device (100) configured for stimulation of at least one nerve or muscle in a body of a subject, the device comprising: a housing (200); and at least one electrical lead (300), and/or at least one stimulation electrode (400); wherein the at least one electrical lead (300) is partly disposed on the housing (200), and wherein the housing (200) comprises modular elements (210), the modular elements (210) being arranged in a stack (211). According to another aspect of this disclosure, a system (900) for electrical nerve stimulation is shown, the system (900) comprising a network of at least two modular devices (100) configured for implantation inside a body of a subject according to one of the preceding claims, wherein each modular device (100) is electrically connected to at least one other modular device (100) through electrical leads (300).

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

16.

PAIR OF INTELLIGENT ELECTRIC CONDUCTORS

      
Document Number 03193300
Status Pending
Filing Date 2020-09-18
Open to Public Date 2022-03-24
Owner NYXOAH SA (Belgium)
Inventor
  • Vossenberg, Marcel
  • Bervoets, Wim
  • Raje, Milind Chandrakant
  • Van Den Heuvel, Koen Erik
  • Vermeiren, Jan

Abstract

Disclosed herein is an implantable device (10) configured for implantation in a body of subject (50), the device comprising: a flexible body (20) and at least one stimulator unit (30) attached to the flexible body (20), wherein the at least one stimulator unit (30) comprises a plurality of electric components (31) encapsulated in a hermetically sealed enclosure (32), a receiving antenna (33), and at least one electric conductor (34) in electrical connection with the plurality of electric components (31).

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings

17.

PAIR OF INTELLIGENT ELECTRIC CONDUCTORS

      
Application Number EP2020076190
Publication Number 2022/058024
Status In Force
Filing Date 2020-09-18
Publication Date 2022-03-24
Owner NYXOAH SA (Belgium)

Abstract

Disclosed herein is an implantable device (10) configured for implantation in a body of subject (50), the device comprising: a flexible body (20) and at least one stimulator unit (30) attached to the flexible body (20), wherein the at least one stimulator unit (30) comprises a plurality of electric components (31) encapsulated in a hermetically sealed enclosure (32), a receiving antenna (33), and at least one electric conductor (34) in electrical connection with the plurality of electric components (31).

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings

18.

Medical implant

      
Application Number 29721611
Grant Number D0915597
Status In Force
Filing Date 2020-01-22
First Publication Date 2021-04-06
Grant Date 2021-04-06
Owner NYXOAH S.A. (Belgium)
Inventor Siman, Guy

19.

METHOD AND PROCESS FOR PLACEMENT AND FIXATION OF A SURGICAL IMPLANT

      
Application Number EP2020073878
Publication Number 2021/037927
Status In Force
Filing Date 2020-08-26
Publication Date 2021-03-04
Owner NYXOAH SA (Belgium)

Abstract

A method of treating obstructive sleep apnea according to this disclosure may include: providing an implant comprising a substantially planar central body portion having a top side and a bottom side; at least two adjustable wing portions; and at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion; forming a surgical opening to expose a genioglossus muscle; exposing a branch of a hypoglossal nerve for stimulation by the implant at least on one side of the geniouglossus; forming at least one pocket on at least one side of the geniouglossus; such that the pocket dimensions are configured to fit the at least one of the at least two wing portions of the device; inserting an implant device through the surgical opening such that the central body extends over the genioglossus and each one of the wing portions is received in the respective at least one pocket; and securing the implant device to the muscle.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers

20.

Implant unit delivery tool

      
Application Number 16911667
Grant Number 11730469
Status In Force
Filing Date 2020-06-25
First Publication Date 2020-12-17
Grant Date 2023-08-22
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik
  • Siman, Guy

Abstract

An implant unit delivery tool is provided. The implant delivery tool may include a body, a holder disposed at a distal end of the body and adapted to hold an implant unit, and an implant activator associated with the body, the implant activator configured to receive power from a power source. The implant activator may be configured to selectively and wirelessly transfer power from the power source to the implant unit during implantation of the implant unit into the body of a subject to cause modulation of at least one nerve in the body of the subject, and determine a degree of nerve modulation response resulting from the selective and wireless transfer of power from the power source to the implant unit claims.

IPC Classes  ?

  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
  • A61N 1/378 - Electrical supply
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61B 5/24 - Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
  • A61B 5/389 - Electromyography [EMG]

21.

METHOD AND SYSTEM FOR ELECTRICAL NERVE STIMULATION

      
Document Number 03140271
Status Pending
Filing Date 2020-05-18
Open to Public Date 2020-11-26
Owner NYXOAH SA (Belgium)
Inventor Tsukran, Roi Moshe

Abstract

Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subject's hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

22.

METHOD AND SYSTEM FOR ELECTRICAL NERVE STIMULATION

      
Application Number EP2020063859
Publication Number 2020/234253
Status In Force
Filing Date 2020-05-18
Publication Date 2020-11-26
Owner NYXOAH SA (Belgium)
Inventor Tsukran, Roi Moshe

Abstract

Disclosed herein is a method for electrical nerve (510) stimulation, the method comprising: generating an electrical stimulation pattern (100) comprising a plurality of successive pulse trains (110), wherein each pulse train (110) has a pulse train amplitude (111); delivering the electrical stimulation pattern (100) to a subject's hypoglossal nerve (510) with a stimulator (300) having at least one electrode (310); modulating the electrical stimulation pattern (100), wherein modulation of the electrical stimulation pattern (100) comprises gradually increasing the pulse train amplitude (111) from one pulse train (110) to a successive pulse train (110) at stimulation onset (101) until a determined target stimulation amplitude (130) is reached; characterized in that modulation of the electrical stimulation pattern (100) further comprises decreasing the target stimulation amplitude (130) to a defined step-down amplitude (140) within each pulse train (110) after the target stimulation amplitude (130) was reached.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

23.

GENIO

      
Application Number 1552793
Status Registered
Filing Date 2020-05-27
Registration Date 2020-05-27
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations; sanitary preparations for medical purposes; transdermal patches for medical purposes including for use in connection with the field of sleep apnea and related sleep disorders; adhesive medical patch including for use in connection with the field of sleep apnea and related sleep disorders; patch for medical purposes including in the field of sleep apnea and related sleep disorders; none of the aforementioned goods for use in the field of dialysis therapy or blood purification. Data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; computer software for use with medical equipment for receiving, analyzing, processing, transmitting, and displaying medical data in the field of sleep disorders; connection cables and cable connectors for the aforesaid goods, namely, medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; rechargeable batteries for medical devices; a charging unit for charging an activation device for activating an implantable stimulator; downloadable instruction manuals for medical devices used for the diagnosis and treatment of sleep apnea and related sleep disorders, and electronic publications in the nature of instruction manuals for medical devices used for the diagnoses and treatment of sleep apnea and related sleep disorders recorded on computer media related thereto. Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; an activation device for activating an implantable stimulator, an activation device for wirelessly activating an implantable stimulator; an activation device with rechargeable battery for activating an implantable stimulator; sterile external stimulator for activating the implantable stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables, all sold as a unit, electrical stimulation system for health and medical purposes and an upper airway stimulation. Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical information in the field of sleep apnea and related sleep disorders via a website.

24.

Programmable external control unit

      
Application Number 16707968
Grant Number 11642534
Status In Force
Filing Date 2019-12-09
First Publication Date 2020-06-04
Grant Date 2023-05-09
Owner Nyxoah SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik
  • Siman, Guy

Abstract

A medical device control unit is provided. The control unit may include a communications interface, a memory, and at least one processing device. The processing device may be configured to cause application of a control signal to a primary antenna associated with a unit external to a subject's body. The processing device may further be configured to monitor a feedback signal indicative of the subject's breathing and store, in the memory, information associated with the feedback signal. The processing device may also cause transmission of the stored information, via the communications interface, to a location remote from the control unit. The processing device may further be configured to receive an update signal, from the location remote from the control unit, and cause application of an updated control signal to the primary antenna based on the update signal.

IPC Classes  ?

  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/04 - Electrodes
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/389 - Electromyography [EMG]
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
  • A61B 5/01 - Measuring temperature of body parts
  • A61B 7/04 - Electric stethoscopes
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

25.

GENIO

      
Application Number 205495400
Status Registered
Filing Date 2020-05-27
Registration Date 2023-09-13
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

(1) Pharmaceutical preparations for the treatment of dermatitis, eczema and psoriasis ; disinfectants for medical apparatus and instruments ; transdermal patches for medical purposes namely for use in the treatment of sleep apnea and related sleep disorders, none of the aforementioned goods for use in the field of dialysis therapy or blood purification; adhesive medical patch containing pharmaceutical preparations primarily for use in the treatment of sleep apnea and related sleep disorders, none of the aforementioned goods for use in the field of dialysis therapy or blood purification; transdermal patch for medical purposes namely for use in the treatment of sleep apnea and related sleep disorders, none of the aforementioned goods for use in the field of dialysis therapy or blood purification ; (2) Data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; Downloadable data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; downloadable computer software for use with medical equipment for receiving, analyzing, processing, transmitting, and displaying medical data in the field of sleep disorders; connection cables and cable connectors for the aforesaid goods, namely, medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; rechargeable batteries for medical devices; a charging unit for charging an activation device for activating an implantable stimulator; downloadable instruction manuals for medical devices used for the diagnosis and treatment of sleep apnea and related sleep disorders, and electronic publications in the nature of instruction manuals for medical devices used for the diagnoses and treatment of sleep apnea and related sleep disorders recorded on computer media related thereto. (3) Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; Electrical stimulation apparatus for the treatment of obstructive sleep apnea namely an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator, an activation device for activating an implantable stimulator, an activation device for wirelessly activating an implantable stimulator, an activation device with rechargeable battery for activating an implantable stimulator, sterile external stimulator for activating the implantable stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, connection cables all sold as a unit and an electrical stimulation system for health and medical purposes and an upper airway stimulation. (1) Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical information in the field of sleep apnea and related sleep disorders via a website.

26.

GENIO

      
Serial Number 79294758
Status Registered
Filing Date 2020-05-27
Registration Date 2021-07-20
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for skin care; sanitary preparations for medical purposes; transdermal patches for medical purposes, namely, for use in the treatment of sleep apnea and related sleep disorders; adhesive medical patch containing pharmaceutical preparations primarily for use in the treatment of sleep apnea and related sleep disorders; transdermal patch for medical purposes, namely, for use in the treatment of sleep apnea and related sleep disorders; none of the aforementioned goods for use in the field of dialysis therapy or blood purification Downloadable data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; downloadable computer software for use with medical equipment for receiving, analyzing, processing, transmitting, and displaying medical data in the field of sleep disorders; connection cables and cable connectors for the aforesaid goods, namely, medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; rechargeable batteries for medical devices; charging appliances for rechargeable equipment, namely, a charging unit for charging an activation device for activating an implantable stimulator; downloadable instruction manuals for medical devices used for the diagnosis and treatment of sleep apnea and related sleep disorders, and electronic publications in the nature of instruction manuals for medical devices used for the diagnoses and treatment of sleep apnea and related sleep disorders recorded on computer media related thereto Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and structural parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; an activation device specially adapted for activating an implantable nerve or muscle stimulator, an activation device specially adapted for wirelessly activating an implantable nerve or muscle stimulator; an activation device with rechargeable battery specially adapted for activating an implantable nerve or muscle stimulator; sterile external nerve or muscle stimulator for activating the implantable nerve or muscle stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables, all sold as a unit; electrical stimulation system for health and medical purposes comprised of electronic nerve and muscle stimulators for upper airway stimulation Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical information in the field of sleep apnea and related sleep disorders via a website

27.

Medical implant

      
Application Number 29591095
Grant Number D0876628
Status In Force
Filing Date 2017-01-17
First Publication Date 2020-02-25
Grant Date 2020-02-25
Owner NYXOAH S.A. (Belgium)
Inventor Siman, Guy

28.

Surgical implant system

      
Application Number 16488141
Grant Number 11707623
Status In Force
Filing Date 2018-02-28
First Publication Date 2020-01-02
Grant Date 2023-07-25
Owner Nyxoah S.A. (Belgium)
Inventor
  • Golan, Shiran
  • Siman, Guy
  • Yosef, Yoel Ben
  • Adimor, Ronen
  • Tsukran, Roi Moshe

Abstract

The disclosed subject matter is directed to a surgical implant and a device for its activation. The surgical implant comprises a substantially planar central body portion having a top side and a bottom side and at least two adjustable wing portions. In addition, the implant comprises at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

29.

Patch

      
Application Number 29596273
Grant Number D0866769
Status In Force
Filing Date 2017-03-07
First Publication Date 2019-11-12
Grant Date 2019-11-12
Owner NYXOAH S.A. (Belgium)
Inventor
  • Yosef, Yoel Ben
  • Adimor, Ronen
  • Tsukran, Roi Moshe

30.

Implant holder and suture guide

      
Application Number 16297974
Grant Number 11478240
Status In Force
Filing Date 2019-03-11
First Publication Date 2019-09-05
Grant Date 2022-10-25
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A delivery system is disclosed having an implant retainer configured to releasably hold an implant unit and maintain the implant unit in a fixation location relative to target tissue in a subject's body during an implantation procedure. A first suture guide portion may be disposed on a first side of the implant retainer and configured to guide a suture needle during the implantation procedure. A second suture guide portion may be disposed on a second side of the implant retainer, opposite the first side, and configured to guide the suture needle after the suture needle exits the first suture guide portion.

IPC Classes  ?

  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/378 - Electrical supply
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
  • H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
  • H02J 50/05 - Circuit arrangements or systems for wireless supply or distribution of electric power using capacitive coupling

31.

Medical device

      
Application Number 29610459
Grant Number D0858753
Status In Force
Filing Date 2017-07-12
First Publication Date 2019-09-03
Grant Date 2019-09-03
Owner NYXOAH S.A. (Belgium)
Inventor
  • Yosef, Yoel Ben
  • Adimor, Ronen
  • Tsukran, Roi Moshe

32.

Implant unit delivery tool

      
Application Number 16044668
Grant Number 10716560
Status In Force
Filing Date 2018-07-25
First Publication Date 2018-11-15
Grant Date 2020-07-21
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik
  • Siman, Guy

Abstract

An implant unit delivery tool is provided. The implant delivery tool may include a body, a holder disposed at a distal end of the body and adapted to hold an implant unit, and an implant activator associated with the body, the implant activator configured to receive power from a power source. The implant activator may be configured to selectively and wirelessly transfer power from the power source to the implant unit during implantation of the implant unit into the body of a subject to cause modulation of at least one nerve in the body of the subject, and determine a degree of nerve modulation response resulting from the selective and wireless transfer of power from the power source to the implant unit claims.

IPC Classes  ?

  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61B 5/04 - Measuring bioelectric signals of the body or parts thereof
  • A61B 5/0488 - Electromyography
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
  • A61N 1/378 - Electrical supply
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

33.

Arced implant unit for modulation of nerves

      
Application Number 15938100
Grant Number 10751537
Status In Force
Filing Date 2018-03-28
First Publication Date 2018-10-04
Grant Date 2020-08-25
Owner Nyxoah SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61B 5/08 - Measuring devices for evaluating the respiratory organs
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61B 5/0488 - Electromyography

34.

Electrical contacts on a medical device patch

      
Application Number 15988423
Grant Number 11191970
Status In Force
Filing Date 2018-05-24
First Publication Date 2018-09-20
Grant Date 2021-12-07
Owner Nyxoah SA (Belgium)
Inventor
  • Mashiach, Adi
  • Ruytjens, Tim

Abstract

A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.

IPC Classes  ?

  • A61N 1/378 - Electrical supply
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems

35.

SURGICAL IMPLANT SYSTEM

      
Document Number 03054180
Status Pending
Filing Date 2018-02-28
Open to Public Date 2018-09-07
Owner NYXOAH SA (Belgium)
Inventor
  • Golan, Shiran
  • Siman, Guy
  • Yosef, Yoel Ben
  • Adimor, Ronen
  • Tsukran, Roi Moshe

Abstract

The disclosed subject matter is directed to a surgical implant and a device for its activation. The surgical implant comprises a substantially planar central body portion having a top side and a bottom side and at least two adjustable wing portions. In addition, the implant comprises at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

36.

SURGICAL IMPLANT SYSTEM

      
Application Number EP2018054913
Publication Number 2018/158305
Status In Force
Filing Date 2018-02-28
Publication Date 2018-09-07
Owner NYXOAH S.A. (Belgium)
Inventor
  • Golan, Shiran
  • Siman, Guy
  • Yosef, Yoel Ben
  • Adimor, Ronen
  • Tsukran, Roi Moshe

Abstract

The disclosed subject matter is directed to a surgical implant and a device for its activation. The surgical implant comprises a substantially planar central body portion having a top side and a bottom side and at least two adjustable wing portions. In addition, the implant comprises at least two connecting members, each one of the at least two connecting members extending from opposite sides of the central body portion, the each one of the at least two connecting members being configured for flexibly connecting each one of the at least two wing portions at opposite sides to said central body portion.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

37.

Miscellaneous Design

      
Application Number 1419116
Status Registered
Filing Date 2018-02-21
Registration Date 2018-02-21
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; activation device for activating implantable stimulator, activation device for wirelessly activating implantable stimulator; activation device with rechargeable battery for activating implantable stimulator; sterile external stimulator for activating the implantable stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables, all sold as a unit, electrical stimulation system for health and medical purposes and an upper airway stimulation.

38.

Nyxoah

      
Application Number 1418400
Status Registered
Filing Date 2018-02-21
Registration Date 2018-02-21
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ?
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; activation device for activating implantable stimulator, activation device for wirelessly activating implantable stimulator; activation device with rechargeable battery for activating implantable stimulator; sterile external stimulator for activating the implantable stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables, all sold as a unit, electrical stimulation system for health and medical purposes and an upper airway stimulation. Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical and other related medical information in the field of sleep apnea and related sleep disorders via a website.

39.

Method and device for treating sleep apnea

      
Application Number 15942251
Grant Number 11273307
Status In Force
Filing Date 2018-03-30
First Publication Date 2018-08-09
Grant Date 2022-03-15
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Scholz, Oliver

Abstract

A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

40.

Devices and methods for low current neural modulation

      
Application Number 15874273
Grant Number 10828492
Status In Force
Filing Date 2018-01-18
First Publication Date 2018-07-26
Grant Date 2020-11-10
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61N 1/378 - Electrical supply
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 2/00 - Magnetotherapy

41.

Transcutaneous power conveyance device

      
Application Number 15897107
Grant Number 10814137
Status In Force
Filing Date 2018-02-14
First Publication Date 2018-07-26
Grant Date 2020-10-27
Owner Nyxoah SA (Belgium)
Inventor
  • Mashiach, Adi
  • Ruytjens, Tim
  • Mashiach, Itzik

Abstract

Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to be received by and retained by a receiver associated with a housing configured for mounting on the carrier.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/378 - Electrical supply
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems

42.

Device and method for snoring detection and control

      
Application Number 15834668
Grant Number 10898717
Status In Force
Filing Date 2017-12-07
First Publication Date 2018-04-05
Grant Date 2021-01-26
Owner Nyxoah SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mueller, Carsten

Abstract

A device for the treatment of snoring is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, an interface configured to receive a feedback signal that varies based upon a breathing pattern of the subject; and at least one processing device. The processing device may be configured to analyze the feedback signal and determine whether the subject is snoring based on the analysis of the feedback signal, and if snoring is detected, cause a hypoglossal nerve modulation control signal to be applied to the primary antenna in order to wirelessly transmit the hypoglossal nerve modulation control signal to a secondary antenna associated with an implant unit configured for location in a body of the subject.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61B 5/08 - Measuring devices for evaluating the respiratory organs
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61B 5/0488 - Electromyography

43.

NYXOAH

      
Serial Number 79238922
Status Registered
Filing Date 2018-02-21
Registration Date 2019-06-18
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ?
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; activation device for activating implantable electrical nerve or muscle stimulator, activation device for wirelessly activating implantable electrical nerve or muscle stimulator; activation device with rechargeable battery for activating implantable electrical nerve or muscle stimulator; sterile external stimulator for activating the implantable electrical nerve or muscle stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected by the medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables for the medical device, all sold as a unit; electrical stimulation system for stimulating upper airway pathways for health and medical purposes Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical and other related health and healthcare information in the field of sleep apnea and related sleep disorders via a website

44.

Miscellaneous Design

      
Serial Number 79239214
Status Registered
Filing Date 2018-02-21
Registration Date 2019-07-02
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ? 10 - Medical apparatus and instruments

Goods & Services

Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; activation device for activating implantable electrical nerve or muscle stimulator, activation device for wirelessly activating implantable electrical nerve or muscle stimulator; activation device with rechargeable battery for activating implantable electrical nerve or muscle stimulator; sterile external stimulator for activating the implantable electrical nerve or muscle stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, an electronic data recorder for the recording of information collected by the medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables for the medical device, all sold as a unit; electrical stimulation system for stimulating upper airway pathways for health and medical purposes

45.

Genio

      
Application Number 1386479
Status Registered
Filing Date 2017-07-17
Registration Date 2017-07-17
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations; sanitary preparations for medical purposes; transdermal patches for medical purposes including for use in connection with the field of sleep apnea and related sleep disorders; adhesive medical patch including for use in connection with the field of sleep apnea and related sleep disorders; patch for medical purposes including in the field of sleep apnea and related sleep disorders; none of the aforementioned goods for use in the field of dialysis therapy or blood purification. Data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; computer software for use with medical equipment for receiving, analyzing, processing, transmitting, and displaying medical data in the field of sleep disorders; connection cables and cable connectors for the aforesaid goods, namely, medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; rechargeable batteries for medical devices; a charging unit for charging an activation device for activating an implantable stimulator; downloadable instruction manuals for medical devices used for the diagnosis and treatment of sleep apnea and related sleep disorders, and electronic publications in the nature of instruction manuals for medical devices used for the diagnoses and treatment of sleep apnea and related sleep disorders recorded on computer media related thereto; electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables, all sold as a unit. Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; an activation device for activating an implantable stimulator, an activation device for wirelessly activating an implantable stimulator; an activation device with rechargeable battery for activating an implantable stimulator; sterile external stimulator for activating the implantable stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, electrical stimulation system for health and medical purposes and an upper airway stimulation. Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical information in the field of sleep apnea and related sleep disorders via a web site.

46.

Control housing for disposable patch

      
Application Number 15589726
Grant Number 11298549
Status In Force
Filing Date 2017-05-08
First Publication Date 2017-08-31
Grant Date 2022-04-12
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik
  • Siman, Guy

Abstract

A medical device control unit is provided. The control unit may include at least one processing device, a circuit electrically coupled to the at least one processing device, and a flexible housing configured to contain the at least one processing device and the circuit. The flexible housing may include at least one connection portion configured to engage a connector protruding from a flexible carrier, and at least one electrical contact electrically coupled to the circuit and configured to establish an electrical connection with an exposed electrical contact on the flexible carrier when the connection portion is engaged with the at least one connection portion.

IPC Classes  ?

  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/04 - Electrodes
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/389 - Electromyography [EMG]
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
  • A61B 5/01 - Measuring temperature of body parts
  • A61B 7/04 - Electric stethoscopes
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

47.

GENIO

      
Serial Number 79225775
Status Registered
Filing Date 2017-07-17
Registration Date 2019-03-26
Owner Nyxoah, société anonyme (Belgium)
NICE Classes  ?
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 09 - Scientific and electric apparatus and instruments
  • 10 - Medical apparatus and instruments
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Pharmaceutical preparations for skin care; sanitary preparations for medical purposes; transdermal patches for medical purposes for help with sleep apnea and related sleep disorders; adhesive medical patch for help with sleep apnea and related sleep disorders; patches for medical purposes for help with sleep apnea and related sleep disorders; none of the aforementioned goods for use in the field of dialysis therapy or blood purification Data management software for use with medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; computer software for use with medical equipment for receiving, analyzing, processing, transmitting, and displaying medical data in the field of sleep disorders; connection cables and cable connectors for the aforesaid goods, namely, medical devices for the diagnosis and treatment of sleep apnea and related sleep disorders; rechargeable batteries for medical devices; a charging unit for charging an activation device for activating an implantable stimulator; downloadable instruction manuals for medical devices used for the diagnosis and treatment of sleep apnea and related sleep disorders, and electronic publications in the nature of instruction manuals for medical devices used for the diagnoses and treatment of sleep apnea and related sleep disorders recorded on computer media related thereto; electronic data recorder for the recording of information collected in the diagnosis of obstructive sleep apnea and related sleep disorders, and data management computer software for use with medical devices for the diagnosis of sleep apnea and related sleep disorders, and connection cables, all sold as a unit Medical devices for the diagnosis and treatment of obstructive sleep apnea and related sleep disorders and component parts and fittings therefor; electrical stimulation apparatus for the treatment of obstructive sleep apnea, namely, an implantable nerve or muscle stimulator made of artificial materials, disposable patch, and a device for implanting the stimulator; an activation device for activating an implantable stimulator, an activation device for wirelessly activating an implantable stimulator; an activation device with rechargeable battery for activating an implantable stimulator; sterile external stimulator for activating the implantable stimulator; patient screening kits for the diagnosis of sleep apnea and related sleep disorders consisting of a medical device for the diagnosis of obstructive sleep apnea and related sleep disorders, electrical stimulation system for health and medical purposes and an upper airway stimulation Medical services, namely, diagnosis and treatment of obstructive sleep apnea and related sleep disorders; medical consultation services in the field of obstructive sleep apnea and related disorders provided to patients and doctors; providing medical information in the field of sleep apnea and related sleep disorders via a web site

48.

Electrical contacts on a medical device patch

      
Application Number 15355981
Grant Number 09993652
Status In Force
Filing Date 2016-11-18
First Publication Date 2017-03-09
Grant Date 2018-06-12
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Ruytjens, Tim

Abstract

A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.

IPC Classes  ?

  • A61N 1/378 - Electrical supply
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems

49.

Method and device for treating sleep apnea based on tongue movement

      
Application Number 15231468
Grant Number 09943686
Status In Force
Filing Date 2016-08-08
First Publication Date 2016-12-01
Grant Date 2018-04-17
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

IPC Classes  ?

  • A61N 1/32 - Applying electric currents by contact electrodes alternating or intermittent currents
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

50.

CONTROL CIRCUIT FOR A BASE STATION FOR TRANSMITTING ENERGY TO A RECEIVER BY MEANS OF AN ELECTRIC RESONANT CIRCUIT, EVALUATION DEVICE, METHOD AND COMPUTER PROGRAMME

      
Application Number EP2015078104
Publication Number 2016/087391
Status In Force
Filing Date 2015-11-30
Publication Date 2016-06-09
Owner NYXOAH S.A. (Belgium)
Inventor
  • Müller, Carsten
  • Koch, Timo

Abstract

Exemplary embodiments relate to a control circuit (202) for a base station (204) for transmitting energy to a receiver (206) by means of an electric resonant circuit (208; 300). The control circuit (202) comprises an evaluation device (210) which is designed to compare energy that has been transmitted to a receiver resonant circuit (212) of the receiver (206) with an energy set value. The control circuit (202) is designed to alter the energy input into the receiver resonant circuit (212) of the receiver (206) by altering a resonant frequency of the resonant circuit (208; 300) on the basis of the result of the comparison.

IPC Classes  ?

  • A61N 1/378 - Electrical supply
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • H02M 3/337 - Conversion of DC power input into DC power output with intermediate conversion into AC by static converters using discharge tubes with control electrode or semiconductor devices with control electrode to produce the intermediate AC using devices of a triode or a transistor type requiring continuous application of a control signal using semiconductor devices only in push-pull configuration
  • H02M 1/00 - Details of apparatus for conversion
  • H02M 7/48 - Conversion of DC power input into AC power output without possibility of reversal by static converters using discharge tubes with control electrode or semiconductor devices with control electrode

51.

Methods for treatment of sleep apnea

      
Application Number 14884964
Grant Number 09415215
Status In Force
Filing Date 2015-10-16
First Publication Date 2016-02-04
Grant Date 2016-08-16
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

52.

Devices for treatment of sleep apnea

      
Application Number 14884977
Grant Number 09415216
Status In Force
Filing Date 2015-10-16
First Publication Date 2016-02-04
Grant Date 2016-08-16
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

53.

Sleep disordered breathing treatment apparatus

      
Application Number 14623190
Grant Number 11253712
Status In Force
Filing Date 2015-02-16
First Publication Date 2015-10-15
Grant Date 2022-02-22
Owner Nyxoah SA (Belgium)
Inventor Mashiach, Adi

Abstract

Some embodiments of the disclosure may include a device for wirelessly powering an implant unit in a body of a subject from a location outside of the body of the subject, wherein the implant unit includes a secondary antenna for wirelessly receiving energy. The device may include a primary antenna configured to be located external to the body of the subject, a circuit electrically connected to the primary antenna, and at least one processor electrically connected to the primary antenna and the circuit. The at least one processor may determine a resonant frequency mismatch between a first resonant frequency associated with the primary antenna and a second resonant frequency associated with the secondary antenna associated with the implant unit; and apply an adjustment to at least one component of the circuit to cause a change in the first resonant frequency associated with the primary antenna and a reduction in the resonant frequency mismatch.

IPC Classes  ?

  • A61N 1/378 - Electrical supply
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
  • H02J 50/90 - Circuit arrangements or systems for wireless supply or distribution of electric power involving detection or optimisation of position, e.g. alignment
  • H02J 50/80 - Circuit arrangements or systems for wireless supply or distribution of electric power involving the exchange of data, concerning supply or distribution of electric power, between transmitting devices and receiving devices
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61F 2/30 - Joints
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons

54.

Electrical contacts on a medical device patch

      
Application Number 14059651
Grant Number 09504828
Status In Force
Filing Date 2013-10-22
First Publication Date 2015-04-23
Grant Date 2016-11-29
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Ruytjens, Tim

Abstract

A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/378 - Electrical supply
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems

55.

DYNAMIC MODIFICATION OF MODULATION THROUGHOUT A THERAPY PERIOD

      
Document Number 03109471
Status In Force
Filing Date 2014-06-17
Open to Public Date 2015-01-15
Grant Date 2023-01-24
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

Abstract of the Disclosure A device for controlling operation of a nerve-modulating implant unit from a location external to the body of the subject is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, and at least one processing device. The processing device may be configured to cause generation of a modulation control signal and application of the modulation control signal to the primary antenna in order to wirelessly transmit the modulation control signal to a secondary antenna on the implant unit to cause modulation of at least one nerve using energy transmitted wirelessly from the primary antenna to the secondary antenna, and cause a plurality of predetermined alterations of at least one characteristic of the modulation control signal over successive applications of the modulation control signal during a therapy period. 71 Date recue/Date Received 2021-02-17

IPC Classes  ?

  • A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating
  • A61B 5/296 - Bioelectric electrodes therefor specially adapted for particular uses for electromyography [EMG]
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • G08C 17/02 - Arrangements for transmitting signals characterised by the use of a wireless electrical link using a radio link

56.

DYNAMIC MODIFICATION OF MODULATION THROUGHOUT A THERAPY PERIOD

      
Document Number 02915077
Status In Force
Filing Date 2014-06-17
Open to Public Date 2015-01-15
Grant Date 2022-06-14
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

A device for controlling operation of a nerve-modulating implant unit from a location external to the body of the subject is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, and at least one processing device. The processing device may be configured to cause generation of a modulation control signal and application of the modulation control signal to the primary antenna in order to wirelessly transmit the modulation control signal to a secondary antenna on the implant unit to cause modulation of at least one nerve using energy transmitted wirelessly from the primary antenna to the secondary antenna, and cause a plurality of predetermined alterations of at least one characteristic of the modulation control signal over successive applications of the modulation control signal during a therapy period.

IPC Classes  ?

  • A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers

57.

Treatment of sleep apnea via bilateral stimulation

      
Application Number 14307040
Grant Number 09463318
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-25
Grant Date 2016-10-11
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

A neuromodulation device is provided. The neuromodulation device may include a carrier configured for implantation in a subject, the carrier including a first elongated arm and a second elongated arm, each extending from a central portion of the carrier. The device may further include a first pair of modulation electrodes arranged on the first elongated arm, a second pair of modulation electrodes arranged on the second elongated arm. The carrier may be sized and shaped for implantation in a vicinity of a hypoglossal nerve to be modulated such that the first pair of modulation electrodes is located to modulate a first hypoglossal nerve on a first side of the subject and the second pair of modulation electrodes is located to modulate a second hypoglossal nerve on a second side of the subject.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

58.

Flexible control housing for disposable patch

      
Application Number 14306853
Grant Number 09643022
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-18
Grant Date 2017-05-09
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik
  • Siman, Guy

Abstract

A medical device control unit may include at least one processing device, a circuit electrically coupled to the at least one processing device, and a flexible housing configured to contain the at least one processing device and the circuit. The flexible housing may include at least one connection portion configured to engage a connector protruding from a flexible carrier, and at least one electrical contact electrically coupled to the circuit and configured to establish an electrical connection with an exposed electrical contact on the flexible carrier when the connection portion is engaged with the at least one connection portion.

IPC Classes  ?

  • A61N 1/04 - Electrodes
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

59.

Antenna buffer layer for an electromagnetic control unit

      
Application Number 14306975
Grant Number 09155899
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-18
Grant Date 2015-10-13
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

A unit for wirelessly transmitting power to an implant unit configured to be located in a subject's body is provided. The unit may include a flexible carrier including an adhesive backing configured for attaching the unit to skin of the subject, an antenna associated with the flexible carrier, the antenna being configured to wirelessly transmit power to the implant unit in response to a signal applied to the antenna, and a buffer layer disposed on the flexible carrier at a position to be between the antenna and the skin of the subject when the carrier is attached to the skin of the subject, the buffer layer being configured to establish an air gap between the skin of the subject and the antenna.

IPC Classes  ?

  • A61N 1/00 - ElectrotherapyCircuits therefor
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

60.

Ceramic encapsulation of an implantable device

      
Application Number 14307015
Grant Number 09308381
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-18
Grant Date 2016-04-12
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

An implantable device is provided. The implantable device may include a flexible carrier configured for implantation in a subject, at least one pair of modulation electrodes associated with the carrier, an antenna configured to receive an electrical signal disposed on the flexible carrier, a circuit electrically coupling the antenna to the at least one pair of modulation electrodes; and a ceramic housing. At least one of the antenna and the circuit may be located within the ceramic housing.

IPC Classes  ?

  • A61N 1/00 - ElectrotherapyCircuits therefor
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

61.

Residual signal feedback-based control of an implant

      
Application Number 14306928
Grant Number 09248302
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-18
Grant Date 2016-02-02
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mueller, Carsten

Abstract

A wireless feedback device for monitoring an implant unit configured for location in a body of a subject is provided. The device may include a flexible substrate configured for removable attachment to the subject's skin, a primary antenna disposed on the flexible substrate, an interface configured to receive from the primary antenna a feedback signal based on wireless interaction with a secondary antenna associated with an implant unit configured to be located in the body of the subject, and at least one processing device. The at least one processing device may be configured detect a feedback signal on the primary antenna after cessation of a transmission to the secondary antenna, analyze the feedback signal to determine information relating to a function of the implant unit, and cause at least one response based on the analysis of the feedback signal.

IPC Classes  ?

  • A61N 1/00 - ElectrotherapyCircuits therefor
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

62.

Remote monitoring and updating of a medical device control unit

      
Application Number 14306953
Grant Number 10512782
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-18
Grant Date 2019-12-24
Owner Nyxoah SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik
  • Siman, Guy

Abstract

A medical device control unit is provided. The control unit may include a communications interface, a memory, and at least one processing device. The processing device may be configured to cause application of a control signal to a primary antenna associated with a unit external to a subject's body. The processing device may further be configured to monitor a feedback signal indicative of the subject's breathing and store, in the memory, information associated with the feedback signal. The processing device may also cause transmission of the stored information, via the communications interface, to a location remote from the control unit. The processing device may further be configured to receive an update signal, from the location remote from the control unit, and cause application of an updated control signal to the primary antenna based on the update signal.

IPC Classes  ?

  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/04 - Electrodes
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61B 17/30 - Surgical pincettes, i.e. surgical tweezers
  • A61B 5/01 - Measuring temperature of body parts
  • A61B 5/0488 - Electromyography
  • A61B 7/04 - Electric stethoscopes
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

63.

Dynamic modification of modulation throughout a therapy period

      
Application Number 14306968
Grant Number 09061162
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-18
Grant Date 2015-06-23
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

A device for controlling operation of a nerve-modulating implant unit from a location external to the body of the subject is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, and at least one processing device. The processing device may be configured to cause generation of a modulation control signal and application of the modulation control signal to the primary antenna in order to wirelessly transmit the modulation control signal to a secondary antenna on the implant unit to cause modulation of at least one nerve using energy transmitted wirelessly from the primary antenna to the secondary antenna, and cause a plurality of predetermined alterations of at least one characteristic of the modulation control signal over successive applications of the modulation control signal during a therapy period.

IPC Classes  ?

  • A61N 1/00 - ElectrotherapyCircuits therefor
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

64.

Device and method for snoring detection and control

      
Application Number 14306916
Grant Number 09849289
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-04
Grant Date 2017-12-26
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mueller, Carsten

Abstract

A device for the treatment of snoring is provided. The device may include a flexible substrate configured for removable attachment to a subject's skin, a primary antenna disposed on the flexible substrate, an interface configured to receive a feedback signal that varies based upon a breathing pattern of the subject; and at least one processing device. The processing device may be configured to analyze the feedback signal and determine whether the subject is snoring based on the analysis of the feedback signal, and if snoring is detected, cause a hypoglossal nerve modulation control signal to be applied to the primary antenna in order to wirelessly transmit the hypoglossal nerve modulation control signal to a secondary antenna associated with an implant unit configured for location in a body of the subject.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61B 5/08 - Measuring devices for evaluating the respiratory organs
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61B 5/0488 - Electromyography

65.

Implant unit for modulation of small diameter nerves

      
Application Number 14306990
Grant Number 10716940
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-04
Grant Date 2020-07-21
Owner Nyxoah SA (Belgium)
Inventor Mashiach, Adi

Abstract

An implant unit configured for implantation into a body of a subject is provided. The implant unit may include an antenna configured to receive a signal, and at least one pair of modulation electrodes configured to be implanted into the body of the subject in the vicinity of at least one nerve to be modulated. The at least one nerve may have a diameter less than about 2 millimeters at a modulation location, and the at least one pair of modulation electrodes may be configured to receive an applied electric signal in response to the signal received by the antenna and generate an electrical field to modulate the at least one nerve from a position spaced apart from the at least one nerve.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61B 5/08 - Measuring devices for evaluating the respiratory organs
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61B 5/0488 - Electromyography

66.

Acred implant unit for modulation of nerves

      
Application Number 14307003
Grant Number 09950166
Status In Force
Filing Date 2014-06-17
First Publication Date 2014-12-04
Grant Date 2018-04-24
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61B 5/08 - Measuring devices for evaluating the respiratory organs
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
  • A61B 5/0488 - Electromyography

67.

Self resonant transmitting device

      
Application Number 14059643
Grant Number 08831730
Status In Force
Filing Date 2013-10-22
First Publication Date 2014-02-20
Grant Date 2014-09-09
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mueller, Carsten

Abstract

A device for powering an implant within a body of a subject from a location external to the subject, wherein the implant requires a threshold rate of power increase in order to operate in at least one mode, may include an antenna configured to wirelessly transmit energy to the implant. The device may also include a power storage unit configured to store energy from a power source incapable of delivering the threshold rate of power increase to enable the implant unit to operate in the at least one mode and a power release unit configured to release a pulse of energy from the power storage unit to the antenna after the power storage unit collects an amount of energy sufficient to enable the implant unit to operate in the at least one mode.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/378 - Electrical supply

68.

Transcutaneous power conveyance device

      
Application Number 14059632
Grant Number 09855032
Status In Force
Filing Date 2013-10-22
First Publication Date 2014-02-20
Grant Date 2018-01-02
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Ruytjens, Tim
  • Mashiach, Itzik

Abstract

Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to be received by and retained by a receiver associated with a housing configured for mounting on the carrier.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/378 - Electrical supply
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type

69.

Method for controlling energy delivery as a function of degree of coupling

      
Application Number 14041598
Grant Number 09409013
Status In Force
Filing Date 2013-09-30
First Publication Date 2014-02-06
Grant Date 2016-08-09
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Scholz, Oliver

Abstract

A method for delivering energy as a function of degree coupling may utilize an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The method may determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

IPC Classes  ?

  • A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply
  • A61N 2/00 - Magnetotherapy
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/00 - Measuring for diagnostic purposes Identification of persons
  • A61N 2/02 - Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets

70.

ELECTRICAL CONTACTS ON A MEDICAL DEVICE PATCH

      
Document Number 02879940
Status In Force
Filing Date 2013-07-26
Open to Public Date 2014-01-30
Grant Date 2021-08-10
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Ruytjens, Tim

Abstract

A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply

71.

IMPLANT SLEEP APNEA TREATMENT DEVICE INCLUDING AN ANTENNA

      
Document Number 02879955
Status In Force
Filing Date 2013-07-26
Open to Public Date 2014-01-30
Grant Date 2021-08-10
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A sleep apnea treatment device may include a flexible carrier configured to be implanted in a body of a subject. The device may also include at least one electrode disposed on the flexible carrier, the at least one electrode being configured to modulate nerve fibers of the subject. A flexible antenna may be disposed on the flexible carrier, the flexible antenna electrically connected to the at least one electrode in a manner permitting at least some energy received by the flexible antenna to be transferred to the at least one electrode. The flexible antenna may include: at least a first conductive trace arranged on a first side of the flexible carrier, the at least a first conductive trace defining at least a first elongated space between portions thereof: and at least a second conductive trace arranged on a second side of the flexible carrier, the at least a second conductive trace defining at least a second elongated space between portions thereof, wherein the at least a first conductive trace is at least partially offset from the at least a second conductive trace such that portions of the first conductive trace overly the at least a second elongated space and wherein portions of the second conductive trace underlay the at least a first elongated space.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply

72.

INSERT TOOL FOR SELECTIVELY POWERING AN IMPLANT UNIT

      
Document Number 02879967
Status In Force
Filing Date 2013-07-26
Open to Public Date 2014-01-30
Grant Date 2021-09-07
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

An implant unit delivery tool is disclosed having an implant tool and an implant activator. The implant tool may be configured to retain an implant unit during an implantation procedure in which the implant unit is fixated to tissue. The implant activator may be associated with the implant tool. Additionally, the implant activator may be configured to selectively transfer power to the implant unit during the implantation procedure to cause modulation of at least one nerve in the body of a subject prior to final fixation of the implant unit to the tissue.

IPC Classes  ?

  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/378 - Electrical supply

73.

Internal resonance matching between an implanted device and an external device

      
Application Number 13951590
Grant Number 09031653
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2015-05-12
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A unit configured for implantation in a subject's body may include a carrier, an implantable circuit associated with the carrier, an antenna arranged on the carrier and configured to wirelessly receive energy from a location external to the subject's body and to provide at least a portion of the energy to the implantable circuit, and at least one component associated with the carrier for receiving energy from the implantable circuit. Wherein the implantable circuit and the antenna have an internal resonant frequency mismatched from an external resonant frequency of an external circuit, to account for resonance frequency variation as a result of implantation in the subject's body.

IPC Classes  ?

  • A61N 1/00 - ElectrotherapyCircuits therefor
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/378 - Electrical supply
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters

74.

Suture holes on a flexible implant

      
Application Number 13951606
Grant Number 08812135
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2014-08-19
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device according to some embodiments may include an implant unit which may include a flexible carrier, an antenna arranged on the flexible carrier, at least one pair of modulation electrodes on the flexible carrier, at least one implantable circuit electrically connected to the at least one pair of modulation electrodes and the antenna; and at least one pair of suture holes passing through the flexible carrier. The at least one pair of suture holes may be arranged on the flexible carrier such that the flexible carrier may be configured to conform to tissue in a subject's body, and such that each suture hole of the at least one pair of suture holes may be positioned to allow suturing to tissue adjacent to the suture holes.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

75.

Implant sleep apnea treatment device including an antenna

      
Application Number 13951856
Grant Number 08903515
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2014-12-02
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A sleep apnea treatment device may include a flexible carrier configured to be implanted in a body of a subject. The device may also include at least one electrode disposed on the flexible carrier, the at least one electrode being configured to modulate nerve fibers of the subject. A flexible antenna may be disposed on the flexible carrier, the flexible antenna electrically connected to the at least one electrode in a manner permitting at least some energy received by the flexible antenna to be transferred to the at least one electrode. The flexible antenna may include: at least a first conductive trace arranged on a first side of the flexible carrier, the at least a first conductive trace defining at least a first elongated space between portions thereof; and at least a second conductive trace arranged on a second side of the flexible carrier, the at least a second conductive trace defining at least a second elongated space between portions thereof, wherein the at least a first conductive trace is at least partially offset from the at least a second conductive trace such that portions of the first conductive trace overly the at least a second elongated space and wherein portions of the second conductive trace underlay the at least a first elongated space.

IPC Classes  ?

  • A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/378 - Electrical supply
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials

76.

Electrical contacts on a medical device patch

      
Application Number 13952027
Grant Number 08948871
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2015-02-03
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Ruytjens, Tim

Abstract

A device for conveying power from a location external to a subject to a location within the subject may include a flexible carrier and an adhesive on a first side of the carrier. A coil of electrically conductive material may be associated with the flexible carrier. A mechanical connector may be associated with the carrier opposite the adhesive, wherein the mechanical connector is configured to retain a housing and permit the housing to rotate relative to the flexible carrier. At least one electrical portion may be associated with the carrier in a manner permitting electrical connection to be maintained between the flexible carrier and the housing as the housing is rotated.

IPC Classes  ?

  • A61N 1/00 - ElectrotherapyCircuits therefor
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/378 - Electrical supply
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems

77.

External resonance matching between an implanted device and an external device

      
Application Number 13952063
Grant Number 09526906
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2016-12-27
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

Some embodiments of the disclosure may include a device for wirelessly powering an implant unit in a body of a subject from a location outside of the body of the subject, wherein the implant unit includes a secondary antenna for wirelessly receiving energy. The device may include a primary antenna configured to be located external to the body of the subject, a circuit electrically connected to the primary antenna, and at least one processor electrically connected to the primary antenna and the circuit. The at least one processor may determine a resonant frequency mismatch between a first resonant frequency associated with the primary antenna and a second resonant frequency associated with the secondary antenna associated with the implant unit; and apply an adjustment to at least one component of the circuit to cause a change in the first resonant frequency associated with the primary antenna and a reduction in the resonant frequency mismatch.

IPC Classes  ?

  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/378 - Electrical supply
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
  • A61N 1/375 - Constructional arrangements, e.g. casings

78.

Implant holder and suture guide

      
Application Number 13952082
Grant Number 09511238
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2016-12-06
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A delivery system is disclosed having an implant retainer configured to releasably hold an implant unit and maintain the implant unit in a fixation location relative to target tissue in a subject's body during an implantation procedure. A first suture guide portion may be disposed on a first side of the implant retainer and configured to guide a suture needle during the implantation procedure. A second suture guide portion may be disposed on a second side of the implant retainer, opposite the first side, and configured to guide the suture needle after the suture needle exits the first suture guide portion.

IPC Classes  ?

  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/378 - Electrical supply
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
  • A61N 1/375 - Constructional arrangements, e.g. casings

79.

Therapy protocol activation triggered based on initial coupling

      
Application Number 13952150
Grant Number 10918376
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2021-02-16
Owner Nyxoah SA (Belgium)
Inventor Mashiach, Adi

Abstract

The present disclosure is directed to a control unit for cooperating with an adhesive patch to convey power from a location external to a subject to a location within the subject. The control unit may include a housing configured for selective mounting on the adhesive patch and may further include at least one processor within the housing. The at least one processor may be configured to activate when the housing is mounted on the adhesive patch and to delay, for a predetermined amount of time following activation of the at least one processor, generation of therapeutic control signals for modulating at least one nerve in the subject's body.

IPC Classes  ?

  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H02J 50/12 - Circuit arrangements or systems for wireless supply or distribution of electric power using inductive coupling of the resonant type
  • A61N 1/378 - Electrical supply
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
  • H02J 50/05 - Circuit arrangements or systems for wireless supply or distribution of electric power using capacitive coupling

80.

Insert tool for selectively powering an implant unit

      
Application Number 13952031
Grant Number 08897880
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2014-11-25
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

An implant unit delivery tool is disclosed having an implant tool and an implant activator. The implant tool may be configured to retain an implant unit during an implantation procedure in which the implant unit is fixated to tissue. The implant activator may be associated with the implant tool. Additionally, the implant activator may be configured to selectively transfer power to the implant unit during the implantation procedure to cause modulation of at least one nerve in the body of a subject prior to final fixation of the implant unit to the tissue.

IPC Classes  ?

  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/378 - Electrical supply
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems

81.

Implant encapsulation

      
Application Number 13952106
Grant Number 08838256
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2014-09-16
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mashiach, Itzik

Abstract

An implant unit may include a substrate and an implantable circuit arranged on the substrate. An encapsulation structure may be disposed over at least a portion of the substrate and at least a portion of the implantable circuit, the encapsulation structure including a parylene layer and a silicon layer disposed over the parylene layer.

IPC Classes  ?

  • A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • A61N 1/378 - Electrical supply

82.

Electrical traces in an implant unit

      
Application Number 13952143
Grant Number 08958893
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2015-02-17
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

The present disclosure is directed to a device. The device includes a flexible carrier and at least one implantable circuit arranged on the flexible carrier. The device further includes at least one meandering electrical trace disposed on the flexible carrier and arranged to establish an electrically conductive path between a first contact point and a second contact point associated with the at least one implantable circuit. The at least one meandering electrical trace is configured to maintain the electrically conductive path during flexing of the flexible carrier.

IPC Classes  ?

  • A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/378 - Electrical supply
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems

83.

Flexible antenna on flexible substrate with adhesive back

      
Application Number 13952152
Grant Number 09095725
Status In Force
Filing Date 2013-07-26
First Publication Date 2014-01-30
Grant Date 2015-08-04
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A medical device may be configured to transmit energy from a position outside of a subject's body to a position inside the subject's body. The device may include a flexible substrate having a thickness of between 5 and 100 micrometers and a flexible antenna comprising between 10 and 15 windings on a first surface of the flexible substrate, the antenna having a transmission frequency of between 6.4 to 8.3 MHz, and wherein the antenna is configured to transmit energy to a penetration depth of at least 1 cm into the subject's body. The device may also include an adhesive disposed on at least one surface of the flexible substrate for adhering to skin of the subject.

IPC Classes  ?

  • A61N 1/378 - Electrical supply
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 17/04 - Surgical instruments, devices or methods for closing wounds or holding wounds closedAccessories for use therewith for suturing woundsHolders or packages for needles or suture materials
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • H04B 5/00 - Near-field transmission systems, e.g. inductive or capacitive transmission systems
  • H02J 7/02 - Circuit arrangements for charging or depolarising batteries or for supplying loads from batteries for charging batteries from AC mains by converters
  • A61N 1/375 - Constructional arrangements, e.g. casings

84.

SYSTEM AND METHOD FOR NERVE MODULATION USING NONCONTACTING ELECTRODES

      
Document Number 02850292
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-05-02
Grant Date 2022-07-12
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

An implant unit configured for implantation into a body of a subject may include an antenna configured to receive a signal. The implant unit may also include at least one pair of modulation electrodes configured to be implanted into the body of the subject in the vicinity of at least one nerve to be modulated, the at least one pair of modulation electrodes being configured to receive an applied electric signal in response to the signal received by the antenna and generate an electrical field to modulate the at least one nerve from a position where the at least one pair of modulation electrodes does not contact the at least one nerve.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

85.

ANTENNA PROVIDING VARIABLE COMMUNICATION WITH AN IMPLANT

      
Document Number 02850445
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-05-02
Grant Date 2020-01-14
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mueller, Carsten

Abstract

A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply

86.

ANTENNA PROVIDING VARIABLE COMMUNICATION WITH AN IMPLANT

      
Document Number 03063266
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-05-02
Grant Date 2022-04-26
Owner NYXOAH SA (Belgium)
Inventor
  • Mueller, Carsten
  • Mashiach, Adi

Abstract

A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub- modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

87.

APPARATUS AND METHOD FOR DETECTING A SLEEP DISORDERED BREATHING PRECURSOR

      
Document Number 02850282
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2022-06-21
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device according to some embodiments may include a primary antenna configured to be located external to a subject. The device may also include at least one processor in electrical communication with the primary antenna and configured to receive a condition signal from an implantable device, the condition signal indicative of a precursor to sleep disordered breathing, and cause transmission of a primary signal from the primary antenna to the implantable device, in response to the condition signal, to stimulate at least one nerve in response to the precursor to sleep disordered breathing.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

88.

DEVICES AND METHODS FOR LOW CURRENT NEURAL MODULATION

      
Document Number 02850289
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2020-02-25
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

89.

MODULATOR APPARATUS CONFIGURED FOR IMPLANTATION

      
Document Number 02850308
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2020-12-22
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

An implant unit according to some embodiments may include a flexible carrier, at least one pair of modulation electrodes on the flexible carrier, and at least one implantable circuit in electrical communication with the at least one pair of modulation electrodes. The at least one pair of modulation electrodes and the at least one circuit may be configured for implantation through derma on an underside of a subject's chin and for location proximate to terminal fibers of the medial branch of the subject's hypoglossaS nerve, such that an electric field extending from the at least one pair of modulation electrodes can modulate one or more of the terminal fibers of the medial branch of the hypoglossal nerve.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/11 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

90.

ELECTRODE CONFIGURATION FOR IMPLANTABLE MODULATOR

      
Document Number 02850313
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2019-12-31
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device according to some embodiments may include an implantable flexible carrier and a pair of electrodes located on the carrier. The electrodes may be spaced from each other by a distance greater than 3 mm, and may be configured to cause, when supplied with an electrical signal, a unidirectional electric field sufficient to modulate at least one nerve.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply

91.

APPARATUS AND METHODS FOR IMPLANT COUPLING INDICATION

      
Document Number 02850434
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2021-03-16
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device is disclosed that includes an external unit configured to communicate with an implant unit beneath the skin of a subject and an indicator associated with the external unit. The indicator is configured to produce an indicator signal when the external unit is within a predetermined range of the implant unit. In addition, the indicator may be configured to vary the indicator signal according to a distance between the external unit and the implant unit. Furthermore, a method of locating an external unit with respect to an implant unit is disclosed that includes detecting a distance between the external unit and the implanted unit located beneath the skin of a subject, producing an indicator signal when the external unit is within a predetermined range of the implant unit, and varying the indicator signal as a function of a distance between the external unit and the implant unit.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply

92.

SYSTEMS AND METHODS FOR DETERMINING A SLEEP DISORDER BASED ON POSITIONING OF THE TONGUE

      
Document Number 02850435
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2021-01-19
Owner NYXOAH SA (Belgium)
Inventor
  • Mueller, Carsten
  • Mashiach, Adi

Abstract

Devices and methods are disclosed that include an external unit comprising at least one processor. The processor may be configured to receive a signal indicative of tongue movement in a subject from an implant unit implanted in the subject, determine whether the tongue movement is representative of sleep disordered breathing, generate a modulation control signal to correct the sleep disordered breathing when the at least one processor determines an occurrence of sleep disordered breathing.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply

93.

Device and method for modulating nerves using parallel electric fields

      
Application Number 13629701
Grant Number 08588941
Status In Force
Filing Date 2012-09-28
First Publication Date 2013-04-04
Grant Date 2013-11-19
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device may include at least one pair of modulation electrodes configured for implantation in the vicinity of a nerve to be modulated such that the electrodes are spaced apart from one another along a longitudinal direction of the nerve to be modulated. The electrodes may be further configured to facilitate an electric field in response to an applied electric signal, the electric field including field lines extending in the longitudinal direction of the nerve to be modulated. The device may further include at least one circuit in electrical communication with the at least one pair of modulation electrodes and being configured to cause application of the electric signal applied at the at least one pair of modulation electrodes.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

94.

Antenna providing variable communication with an implant

      
Application Number 13629725
Grant Number 08577478
Status In Force
Filing Date 2012-09-28
First Publication Date 2013-04-04
Grant Date 2013-11-05
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Mueller, Carsten

Abstract

A device may include a primary antenna configured to be located external to a subject and at least one processor in electrical communication with the primary antenna. The at least one processor may be configured to cause transmission of a primary signal from the primary antenna to an implantable device, wherein the implantable device includes at least one pair of modulation electrodes. The at least one processor may be further configured to adjust one or more characteristics of the primary signal to generate a sub-modulation control signal adapted so as not to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device and to generate a modulation control signal adapted so as to cause a neuromuscular modulation inducing current at the at least one pair of modulation electrodes when received by the implantable device.

IPC Classes  ?

  • A61N 1/08 - Arrangements or circuits for monitoring, protecting, controlling or indicating

95.

System and method for nerve modulation using noncontacting electrodes

      
Application Number 13629741
Grant Number 08577466
Status In Force
Filing Date 2012-09-28
First Publication Date 2013-04-04
Grant Date 2013-11-05
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

An implant unit configured for implantation into a body of a subject may include an antenna configured to receive a signal. The implant unit may also include at least one pair of modulation electrodes configured to be implanted into the body of the subject in the vicinity of at least one nerve to be modulated, the at least one pair of modulation electrodes being configured to receive an applied electric signal in response to the signal received by the antenna and generate an electrical field to modulate the at least one nerve from a position where the at least one pair of modulation electrodes does not contact the at least one nerve.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

96.

Devices and methods for low current neural modulation

      
Application Number 13629748
Grant Number 08700183
Status In Force
Filing Date 2012-09-28
First Publication Date 2013-04-04
Grant Date 2014-04-15
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device may include an implantable circuit and at least one pair of implantable electrodes, in electrical communication with the implantable circuit. The circuit and the electrodes may configured for implantation in a subject in the vicinity of a nerve. The circuit may be configured to deliver to the electrodes an electrical signal having a current less than about 1.6 milliamps, and the electrodes may be configured to emit an electric field such that a portion of the field lines extend along a length of the nerve such that the delivery of the electrical signal of less than about 1.6 milliamps causes modulation of the nerve.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

97.

Apparatus and method for controlling energy delivery as a function of degree of coupling

      
Application Number 13629762
Grant Number 08577467
Status In Force
Filing Date 2012-09-28
First Publication Date 2013-04-04
Grant Date 2013-11-05
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Scholz, Oliver

Abstract

A device for delivering energy as a function of degree coupling may include an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The device may further include a primary antenna associated with the at least one processor. The processor may be configured to determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode

98.

APPARATUS AND METHODS FOR FEEDBACK-BASED NERVE MODULATION

      
Document Number 02850311
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2021-07-06
Owner NYXOAH SA (Belgium)
Inventor Mashiach, Adi

Abstract

A device according to some embodiments may include a housing configured for location external to a body of a subject The device may also include at least one processor associated with the housing and configured to communicate with a circuit implanted in the subject within proximity to a tongue of the subject, wherein the circuit is in electrical communication with at least one electrode, receive a physiological signal from the subject via the circuit, and send a control signal to the implanted circuit in response to the physiological signal, wherein the control signal is predetermined to activate neuromuscular tissue within the tongue.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators

99.

APPARATUS AND METHOD FOR CONTROLLING ENERGY DELIVERY AS A FUNCTION OF DEGREE OF COUPLING

      
Document Number 02850436
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2021-06-22
Owner NYXOAH SA (Belgium)
Inventor
  • Mashiach, Adi
  • Scholz, Oliver

Abstract

A device for delivering energy as a function of degree coupling may include an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The device may further include a primary antenna associated with the at least one processor. The processor may be configured to determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

IPC Classes  ?

  • A61N 1/05 - Electrodes for implantation or insertion into the body, e.g. heart electrode
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/36 - Applying electric currents by contact electrodes alternating or intermittent currents for stimulation, e.g. heart pace-makers
  • A61N 1/372 - Arrangements in connection with the implantation of stimulators
  • A61N 1/375 - Constructional arrangements, e.g. casings
  • A61N 1/378 - Electrical supply

100.

APPARATUS AND METHOD FOR CONTROLLING ENERGY DELIVERY AS A FUNCTION OF DEGREE OF COUPLING

      
Document Number 03117620
Status In Force
Filing Date 2012-09-28
Open to Public Date 2013-04-04
Grant Date 2023-09-26
Owner NYXOAH SA (Belgium)
Inventor
  • Scholz, Oliver
  • Mashiach, Adi

Abstract

A device for delivering energy as a function of degree coupling may include an external unit configured for location external to a body of a subject and at least one processor associated with the implant unit and configured for electrical communication with a power source. The device may further include a primary antenna associated with the at least one processor. The processor may be configured to determine a degree of coupling between the primary antenna and a secondary antenna associated with the implant unit, and regulate delivery of power to the implant unit based on the degree of coupling between the primary antenna and the secondary antenna.

IPC Classes  ?

  • A61N 1/378 - Electrical supply
  • A61B 5/113 - Measuring movement of the entire body or parts thereof, e.g. head or hand tremor or mobility of a limb occurring during breathing
  • A61F 5/56 - Devices for preventing snoring
  • A61N 1/04 - Electrodes
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