A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.
B65B 3/04 - Methods of, or means for, filling the material into the containers or receptacles
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
B65D 21/02 - Containers specially shaped, or provided with fittings or attachments, to facilitate nesting, stacking, or joining together
B65B 7/28 - Closing semi-rigid or rigid containers or receptacles not deformed by, or not taking-up shape of, contents, e.g. boxes or cartons by applying separate preformed closures, e.g. lids, covers
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 55/02 - Sterilising, e.g. of complete packages
A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
The invention proposes a device (1) for controlling the temperature of products to be frozen during a freeze drying process. This device (1) is characterized in that at least one Peltier element (3) is present.
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
F25B 21/02 - Machines, plants or systems, using electric or magnetic effects using Peltier effectMachines, plants or systems, using electric or magnetic effects using Nernst-Ettinghausen effect
3.
Coating apparatus for coating an inside of a hollow body with an atomized fluid
A coating device for coating an inside of a hollow body with an atomized fluid has at least one atomizing tube enclosing an atomizing channel. A pressurized propellant gas for atomizing an unatomized fluid can be introduced into the atomizing tube. The atomizing tube has at least one outlet opening and further has at least one hollow needle having a discharge opening for the unatomized fluid. The at least one hollow needle interacts with the atomizing channel and is arranged essentially coaxially thereto. The atomizing tube and the hollow needle form a Venturi arrangement.
B05D 1/02 - Processes for applying liquids or other fluent materials performed by spraying
B05D 7/22 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to internal surfaces, e.g. of tubes
B05B 7/04 - Spray pistolsApparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
B05B 13/06 - Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups specially designed for treating the inside of hollow bodies
B05B 13/02 - Means for supporting workArrangement or mounting of spray headsAdaptation or arrangement of means for feeding work
B05B 13/04 - Means for supporting workArrangement or mounting of spray headsAdaptation or arrangement of means for feeding work the spray heads being moved during operation
B05B 7/06 - Spray pistolsApparatus for discharge with one outlet orifice surrounding another approximately in the same plane
B05C 7/08 - Apparatus specially designed for applying liquid or other fluent material to the inside of hollow work by devices moving in contact with the work for applying liquids or other fluent materials to the inside of tubes
4.
Device and method for mounting a pharmaceutical application aid
A device (1) for assembly of a pharmaceutical application aid (51), particularly a pen, is proposed. The device (1) is characterized by a holding device (3) for fixation of a first housing sleeve (5) that accommodates a pharmaceutical container, particularly a carpule (23), and by a stop (43) for limiting a displacement of a second housing sleeve (35) relative to the first housing sleeve (5).
A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A piston for a medical hollow body such as a syringe or a carpule includes at least one sliding surface for contact with the hollow body. The piston has at least one receiving area in which a lubricant can be received, and at least one dispensing mechanism for dispensing the at least one lubricant from the at least one receiving area to the at least one sliding surface.
A syringe includes a syringe cylinder and a distal end designed as a syringe cone. The distal end comprises a region set back in a radial direction such that an edge extending in the circumferential direction is formed. The edge has a first chamfer, and comprises an attachment piece having a clamping region. Holding forces are introduced from the attachment piece via the clamping region in the region of the syringe set back in a radial direction. The clamping region comprises a distal edge. The the distal edge of the clamping region has a second chamfer.
A device for checking the seal-tightness of closure caps on medical hollow bodies has a drive, a retaining element for the hollow body, and a retaining device for the closure cap. The retaining device is pivotably supported relative to the retaining element. The device further includes a sensor for the relative rotation of the retaining device with respect to the retaining element. A torque may be applied to the closure cap by the drive, the retaining element, and the retaining device. A hollow body and a closure cap are gripped by the retaining device and the retaining element from the same side, as viewed along the longitudinal axis of a hollow body.
G01L 5/24 - Apparatus for, or methods of, measuring force, work, mechanical power, or torque, specially adapted for specific purposes for determining value of torque or twisting moment for tightening a nut or other member which is similarly stressed
G01L 3/14 - Rotary-transmission dynamometers wherein the torque-transmitting element is other than a torsionally-flexible shaft
8.
Device for controlling the temperature of products to be frozen
A device for controlling the temperature of products to be frozen during a freeze drying process includes a plurality of Peltier elements and at least one magazine including different areas for accommodating products to be frozen. The Peltier elements are separably controllable such that the different areas of the magazine are maintainable at different temperatures during a freeze drying process.
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
F25B 21/02 - Machines, plants or systems, using electric or magnetic effects using Peltier effectMachines, plants or systems, using electric or magnetic effects using Nernst-Ettinghausen effect
A device for large-scale lyophilization of pharmaceutical solutions in medical hollow bodies, includes a lyophilization device and at least one camera. Images of at least one pharmaceutical solution to be lyophilized are recorded by the at least one camera. The images may be used for controlling and/or monitoring the lyophilization process.
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
10.
Method for filling dual-chamber systems in pre-sterilizable carrier systems and pre-sterilizable carrier system
A method for filling dual-chamber systems in pre-sterilizable carrier systems includes providing at least one washed, siliconized and sterilized dual-chamber system in a magazine. The dual-chamber system includes respective separating elements separating the two chambers from each other. The magazine accommodates at least one dual-chamber system and is arranged in a container that is sealed with a closing element. The method additionally includes introducing the container into a clean room; opening the container and filling a first chamber of the at least one dual-chamber system; and closing the first chamber. The method further includes filling a second chamber of the at least one dual-chamber system; closing the second chamber; and removing the system from the clean room.
A container for medical products has at least one chamber. At least two lyophilized active substances and/or auxiliary substances are jointly present in the at least one chamber.
B65D 25/08 - Partitions with provisions for removing or destroying, e.g. to facilitate mixing of contents
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
A61J 1/00 - Containers specially adapted for medical or pharmaceutical purposes
12.
Coating apparatus for coating an inside of a hollow body with an atomized fluid
A coating device for coating an inside of a hollow body with an atomized fluid has at least one atomizing tube enclosing an atomizing channel. A pressurized propellant gas for atomizing an unatomized fluid can be introduced into the atomizing tube. The atomizing tube has at least one outlet opening and further has at least one hollow needle having a discharge opening for the unatomized fluid. The at least one hollow needle interacts with the atomizing channel and is arranged essentially coaxially thereto. The atomizing tube and the hollow needle form a Venturi arrangement.
B05B 7/04 - Spray pistolsApparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
B05B 13/06 - Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups specially designed for treating the inside of hollow bodies
B05D 7/22 - Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to internal surfaces, e.g. of tubes
B05C 7/08 - Apparatus specially designed for applying liquid or other fluent material to the inside of hollow work by devices moving in contact with the work for applying liquids or other fluent materials to the inside of tubes
B05B 7/06 - Spray pistolsApparatus for discharge with one outlet orifice surrounding another approximately in the same plane
13.
Device for placing a stopper while simultaneously checking that the stopper is correctly positioned
A device places a plug and simultaneously checks a correct position alignment of the plug with a holding element for fixing a hollow body. The device has at least one first and one second opening and a plug placement mechanism with which the plug is be inserted into the second opening of the hollow body. The device has a measuring head that is traversed by at least one channel. The channel can be fluidically connected to the first opening of the hollow body. The device can further include a pressure sensor which can be fluidically connected to the channel of the measuring head.
G01M 3/26 - Investigating fluid tightness of structures by using fluid or vacuum by measuring rate of loss or gain of fluid, e.g. by pressure-responsive devices, by flow detectors
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
The object of the invention is therefore to provide an x-ray device that is simple to construct and can be inexpensively produced. This object is achieved by the proposed x-ray device for examining syringe caps having a cannula and having the features that is an x-ray source, an x-ray detector, and a holder. The x-ray device is characterized in that the syringe cap is arranged in the beam path so that its longitudinal axis coincides with the main axis of the beam path. The syringe cap is thus impinged from above and from below with x-rays, in order to examine the position of the cannula.
G01N 23/04 - Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups , or by transmitting the radiation through the material and forming images of the material
15.
PISTON FOR A MEDICAL HOLLOW BODY, AND MEDICAL HOLLOW BODIES
The invention relates to a piston (5) for a medical hollow body (1), particularly a syringe or a carpule, comprising at least one sliding surface (19) for contact with the hollow body (1). The piston (5) is characterized by at least one receiving area (21), in which a lubricant can be received, and by at least one dispensing means for dispensing the at least one lubricant from the at least one receiving area (21) to the at least one sliding surface (19).
The invention relates to a piston (5) for a medical hollow body (1), particularly a syringe or a carpule, comprising at least one sliding surface (19) for contact with the hollow body (1). The piston (5) is characterized by at least one receiving area (21), in which a lubricant can be received, and by at least one dispensing means for dispensing the at least one lubricant from the at least one receiving area (21) to the at least one sliding surface (19).
A device (1) for assembly of a pharmaceutical application aid (51), particularly a pen, is proposed. The device (1) is characterized by a holding device (3) for fixation of a first housing sleeve (5) that accommodates a pharmaceutical container, particularly a carpule (23), and by a stop (43) for limiting a displacement of a second housing sleeve (35) relative to the first housing sleeve (5).
A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
Proposed is a syringe (1) comprising a syringe cylinder (5), a distal end (7)designed as a syringe cone, and wherein the distal end (7) comprises a region (9)set back in a radial direction such that an edge (11) extending in thecircumferential direction is formed, and wherein said edge (11) has a chamfer,and comprises an attachment piece (13) having a clamping region (15), andwherein holding forces are introduced from the attachment piece (13) via theclamping region (15) in the region (9) of the syringe (1) set back in a radialdirection, and wherein the clamping region (15) comprises a distal edge (17). Thesyringe (1) is characterized in that the distal edge (17) of the clamping region (15)has a chamfer.
The invention relates to a syringe (1), comprising a syringe cylinder (5), a distal end (7) designed as a syringe cone, wherein said distal end (7) has a region (9) set back in a radial direction such that an edge (11) extending in the circumferential direction is formed, wherein said edge (11) has a chamfer, and comprising an attachment piece (13) having a clamping region (15), wherein holding forces are introduced from the attachment piece (13) via the clamping region (15) into the region (9) of the syringe (1) set back in a radial direction, and wherein the clamping region (15) comprises a distal edge (17). Said syringe (1) is characterized in that the distal edge (17) of the clamping device (15) has a chamfer.
A syringe or carpule includes a cylinder that surrounds a cavity and comprises an end that has an access to the cavity, membrane seals the access and has a puncture area that can be punctured by a needle. A two-part cap has a predetermined breaking line and spans the membrane. A cover device covers the puncture area of the membrane in a sterile manner and comprises a sealing area spanning the puncture area. The sealing area covers the puncture area in a sterile manner regardless of axial forces to be applied in the area of the predetermined breaking line.
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
The invention relates to an injection assembly (1), comprising a hollow cylinder (3) for receiving at least one medicinal active ingredient, wherein the hollow cylinder (3) has a pierceable sealing element (5) at the distal end thereof by means of which it can be sealed closed, a sleeve cap (11) that is arranged at the distal end of the hollow cylinder (3) and can be engaged into the sealing element (5) by the clamping forces so that it seals the hollow cylinder (3) closed, an attachment piece (25) that can be arranged in the region of the sleeve cap (11) - preferably concentrically thereto - wherein the attachment piece (25) comprises a hollow needle element (27) through which the sealing element (5) can be pierced and which has a central channel (29) through which a fluid medium can be conducted, at least one fastening means (33) that interacts with at least one other fastening means (21) arranged in the region of the sleeve cap (11) in order to fix the position of the attachment piece (25) relative to the sleeve cap (11) at least in the axial direction, and a connection element (35) that can be used to couple an injection device (41) to the attachment piece (25), and an injection device (41) that can be coupled to the attachment piece (25) and has a channel (43) through which a fluid medium can be conducted. The injection assembly (1) is characterized in that it comprises at least one equalization volume by which active ingredient volumes entering into the hollow needle element (27) upon piercing of the sealing element (5) can be received so that they remain in the at least one equalization volume and do not readily escape from the injection device (41) when it is coupled to the attachment piece (25).
The invention relates to an attachment or a cartridge comprising a sealing element having an opening for a medium located in the syringe or cartridge or to be introduced into the syringe or cartridge. The attachment is characterized by an actuating device which, in a first functional position, exerts a force on the wall of the opening in such a way that the opening is closed, and leaves the opening open in a second functional position.
A device for applying a coating onto a cover surface (11) of a medical hollow body (9) is proposed, said device being characterized by at least one nozzle (5, 5', 5") and one support (7) holding the at least one nozzle (5, 5', 5"), wherein the coating can be applied to the cover surface (11) of the medical hollow body (9) in a non-contact fashion by way of the at least one nozzle (5, 5', 5").
B05B 13/02 - Means for supporting workArrangement or mounting of spray headsAdaptation or arrangement of means for feeding work
B05B 13/04 - Means for supporting workArrangement or mounting of spray headsAdaptation or arrangement of means for feeding work the spray heads being moved during operation
B05C 5/02 - Apparatus in which liquid or other fluent material is projected, poured or allowed to flow on to the surface of the work from an outlet device in contact, or almost in contact, with the work
The invention relates to a coating device (1) for coating an inside (51) of a hollow body (49) with an atomized fluid. It is thereby provided that the coating device (1) has at least one atomizing tube (5) enclosing an atomizing channel (11), in which atomizing tube pressurized propellant gas for atomizing an unatomized fluid can be introduced and which has at least one outlet opening (9), and further has at least one hollow needle (13) having a discharge opening (15) for the unatomized fluid, which interacts with the atomizing channel (11) and is arranged essentially coaxially thereto, whereby it is provided that the atomizing tube (5) and the hollow needle (13) form a Venturi arrangement (19).
B05B 7/04 - Spray pistolsApparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
B05B 13/06 - Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups specially designed for treating the inside of hollow bodies
25.
METHOD FOR FILLING DUAL-CHAMBER SYSTEMS IN PRE-STERILIZABLE CARRIER SYSTEMS AND PRE-STERILIZABLE CARRIER SYSTEM
The invention relates to a method for filling dual-chamber systems (3) in pre-sterilizable carrier systems (1), which method comprises the following steps: Providing at least one washed and sterilized dual-chamber system (3) in a magazine (9), the dual-chamber system comprising respective separating elements (7) separating the two chambers (5, 5') from each other, the magazine (9) accommodating at least one dual-chamber system (3) and being arranged in a container (11) that is sealed with a closing element (13); introducing the container (11) into a clean room; opening the container (11) and filling a first chamber (5) of the at least one dual-chamber system (3); closing the first chamber (5); filling a second chamber (5') of the at least one dual-chamber system (3); closing the second chamber (5');removing from the clean room.
A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 55/02 - Sterilising, e.g. of complete packages
26.
CONTAINER FOR MEDICAL PRODUCTS AND METHOD FOR PRODUCTION OF SAID CONTAINER
A container (1) for medical products is proposed which has at least one chamber (3) and which is characterized in that at least two lyophilized active substances and/or auxiliary substances (W1, W3, W5, W7) are jointly present in the at least one chamber (3).
A61K 9/19 - Particulate form, e.g. powders lyophilised
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
A device is proposed for large-scale lyophilization of pharmaceutical solutions inmedical hollow bodies, comprising a lyophilization device and at least one camera(9). Images of at least one pharmaceutical solution to be lyophilized are recordedby the at least one camera (9). The device is characterized in that the images maybe used for controlling and/or monitoring the lyophilization process.
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
A pre-sterilizable carrier system, comprising at least one sterilized dual- chamber system (3) having two chambers (5, 5'), the dual-chamber system (3) comprising a separating element (7) separating the two chambers (5, 5') from one another; a magazine (9) that accommodates the at least one dual-chamber system (3); and a container (11); wherein the magazine (9) is arrangeable in the container (11), wherein the container (11) is sealable with a closure element (13), and wherein the container (11) comprises plastic, that plastic is elastically deformable.
B65D 81/24 - Adaptations for preventing deterioration or decay of contentsApplications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
29.
METHOD FOR FILLING DUAL-CHAMBER SYSTEMS IN PRE-STERILIZABLE CARRIER SYSTEMS AND PRE-STERILIZABLE CARRIER SYSTEM
The invention relates to a method for filling dual-chamber systems (3) in pre-sterilizable carrier systems (1), which method comprises the following steps: making at least one washed, siliconized and sterilized dual-chamber system (3) available in a magazine (9), the dual-chamber system comprising respective separating elements separating the two chambers (5, 5') from each other, the magazine (9) accommodating at least one dual-chamber system (3) and being arranged in a container (11) that is sealed with a closing element (13); introducing the container (11) into a clean room; opening the container (11) and filling a first chamber (5) of the at least one dual-chamber system (3); closing the first chamber (5); filling a second chamber (5') of the at least one dual-chamber system (3); closing the second chamber (5'); removing the system from the clean room.
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 55/02 - Sterilising, e.g. of complete packages
A61J 1/20 - Arrangements for transferring fluids, e.g. from vial to syringe
30.
DEVICE WITH AT LEAST ONE CHAMBER FOR RECEIVING A MEDICAMENT OR A SAMPLE VOLUME
A device (1) with at least one chamber (3) for receiving a medicament (M) or a sample volume and with a plunger element (5) that can be moved in the device (1) is proposed, which device (1) comprises a syringe or carpule, a multi-chamber or twin-chamber system, an autoinjector or pen and is characterized in that pressure forces resulting from a chemical reaction can be introduced into the plunger element (5) and cause a movement of the plunger element (5).
A method for filling dual-chamber systems (3) in pre-sterilizable carrier systems (1) is proposed, which comprises the following steps: provision of at least one washed and sterilized dual-chamber system (3) with respectively one separating element separating the two chambers (5, 5') from one another in a magazine (9), which accommodates the at least one dual-chamber system (3), wherein the magazine (9) is arranged in a container (11) sealed with a closure element (13); feeding the container (11) into a clean room; opening the container (11) and filling a first chamber (5) of the at least one dual-chamber system (3); closing the first chamber (5) with a gas-permeable closure element (19); freeze drying the solution (L1) contained in the first chamber (5); closing the first chamber (5) with a closure element (19); filling a second chamber (5') of the at least one dual-chamber system (3); closing the second chamber (5'); discharge from the clean room.
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 55/00 - Preserving, protecting or purifying packages or package contents in association with packaging
32.
DEVICE AND METHOD FOR CHECKING THE LEAK TIGHTNESS OF CAPS ON MEDICAL HOLLOW BODIES
A device (1) is proposed for checking the seal-tightness of closure caps (13) on medical hollow bodies (9), having a drive (3), a retaining element (7) for the hollow body (9), and a retaining device (11) for the closure cap (13), wherein the retaining device (11) is pivotably supported relative to the retaining element (7). Also proposed is a sensor for the relative rotation of the retaining device (11) with respect to the retaining element (7). A torque may be applied to the closure cap (13) by means of the drive (3), the retaining element (7), and the retaining device (11). A hollow body (9) and a closure cap (13) are gripped by the retaining device (11) and the retaining element (7) from the same side, as viewed along the longitudinal axis (19) of a hollow body (9).
ARZNEIMITTEL GMBH APOTHEKER VETTER & CO RAVENSBURG (Germany)
Inventor
Böttger, Frank
Häuptle, Martin
Abstract
The invention relates to a device for lyophilizing pharmaceutical solutions in medical hollow bodies on a large scale, comprising a lyophilization device and at least one camera (9), images of at least one pharmaceutical solution to be lyophilized being recorded by the at least one camera (9). The device is characterized in that the images are used to regulate and/or control the lyophilization process.
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
34.
METHOD FOR FILLING DUAL-CHAMBER SYSTEMS IN PRE-STERILIZABLE CARRIER SYSTEMS AND PRE-STERILIZABLE CARRIER SYSTEM
The invention relates to a method for filling dual-chamber systems (3) in pre-sterilizable carrier systems (1), which method comprises the following steps: making at least one washed, siliconized and sterilized dual-chamber system (3) available in a magazine (9), the dual-chamber system comprising respective separating elements separating the two chambers (5, 5') from each other, the magazine (9) accommodating at least one dual-chamber system (3) and being arranged in a container (11) that is sealed with a closing element (13); introducing the container (11) into a clean room; opening the container (11) and filling a first chamber (5) of the at least one dual-chamber system (3); closing the first chamber (5) with a gas-permeable closing element (19); lyophilizing the solution (L1) present in the first chamber (5); closing the first chamber (5) with a closing element (19); filling a second chamber (5') of the at least one dual-chamber system (3); closing the second chamber (5'); removing the system from the clean room.
B65B 3/00 - Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans or jars
B65B 55/00 - Preserving, protecting or purifying packages or package contents in association with packaging
35.
CONTAINER FOR MEDICAL PRODUCTS AND METHOD FOR PRODUCTION OF SAID CONTAINER
A container (1) for medical products is proposed which has at least one chamber (3) and which is characterized in that at least two lyophilized active substances and/or auxiliary substances (W1, W3, W5, W7) are present jointly in the at least one chamber (3).
A61J 1/00 - Containers specially adapted for medical or pharmaceutical purposes
A61K 9/19 - Particulate form, e.g. powders lyophilised
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
The invention relates to a coating apparatus (1) for coating an inner side (51) of a hollow body (49) with an atomized fluid. It is provided that the coating apparatus (1) comprises at least one atomizing tube (5), which encloses an atomizing channel (11) and into which pressurized propellant gas for atomizing an unatomized fluid can be introduced, and which has at least one outlet opening (9), and furthermore comprises at least one hollow needle (13) with a discharge opening (15) for the unatomized fluid, which interacts with the atomizing channel (11) and is arranged substantially coaxially thereto, it being provided that the atomizing tube (5) and the hollow needle (13) form a Venturi arrangement (19).
B05B 7/04 - Spray pistolsApparatus for discharge with arrangements for mixing liquids or other fluent materials before discharge
B05B 13/06 - Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups specially designed for treating the inside of hollow bodies
37.
DEVICE AND METHOD FOR CHECKING THE LEAK TIGHTNESS OF CAPS ON MEDICAL HOLLOW BODIES
The invention relates to a device (1) for checking the leak tightness of caps (13) on medical hollow bodies (9), having a drive (3), a retaining element (7) for the hollow body (9), a retaining device (11) for the cap (13), wherein the retaining device (11) is pivot-supported relative to the retaining element (7), and a relative rotation sensor for the retaining device (11) opposite to the retaining element (7), wherein a torque can be applied to the cap (13) by means of the drive (3), the retaining element (7) and the retaining device (11), and wherein a hollow body (9) and a cap (13) are detected by the retaining device (11) and the retaining element (7) from the same side – as viewed along the longitudinal axis (19) of a hollow body (9).
A device (1) is proposed for placing a plug (17) while simultaneously checking a correct position alignment of the plug (17), with a holding element for fixing a hollow body (15), which has at least one first and one second opening (21, 25); and with a plug placement means (27), with which the plug (17) can be inserted into the second opening (25) of the hollow body (15). The device is distinguished by a measuring head (5) that is traversed by at least one channel (11), wherein the channel (11) can be fluidically connected to the first opening (21) of the hollow body (15), and by a pressure sensor (3), which can be fluidically connected to the channel (11) of the measuring head (5).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
B65D 3/00 - Rigid or semi-rigid containers having bodies or peripheral walls of curved or partially-curved cross-section made by winding or bending paper without folding along defined lines
39.
DEVICE FOR PLACING A STOPPER WHILE SIMULTANEOUSLY CHECKING THAT THE STOPPER IS CORRECTLY POSITIONED
A device (1) is proposed for placing a stopper (17) while simultaneously checking that the stopper (17) is correctly positioned, with a retaining element for securing a hollow body (15) which has a first opening and a second opening (21, 25), and with a stopper-placing means (27) with which the stopper (17) can be introduced into the second opening (25) in the hollow body (15). The device (1) is distinguished by a measuring head (5) through which at least one passage (11) passes, wherein the passage (11) can be brought into fluidic connection with the first opening (21) in the hollow body (15), and by a pressure transducer (3) which can be brought into fluidic connection with the passage (11) in the measuring head (5).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
B65D 3/00 - Rigid or semi-rigid containers having bodies or peripheral walls of curved or partially-curved cross-section made by winding or bending paper without folding along defined lines
The invention relates to an attachment for a syringe or cartridge having a cannula, wherein the attachment comprises a sealing element, which is molded onto the cannula.
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A syringe includes a syringe cylinder, a sealing plug movably disposed within the syringe cylinder, and with a plunger cooperating with the sealing plug. A safety device prevents a sliding back of the sealing plug within the syringe cylinder in any position the sealing plug assumes within the syringe cylinder. The safety device has a locking element which engages at the plunger in any position the plunger assumes within the syringe cylinder. The locking element is attached to a retaining fixture and protrudes from the retaining fixture same such that an attachment point of the locking element is closer to the sealing plug at the retaining fixture than the free end of the locking element opposite of the attachment point.
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
42.
SYRINGE SYSTEM AND METHOD FOR THE PRODUCTION THEREOF
The invention relates to a syringe system having a pre-filled syringe (1) comprising a hollow syringe body (3) for receiving a medical active agent, said body having a first end (11) for discharging the active agent and an open second end (13), a stopper (7) that can be displaced in the syringe body (3) and by means of which a region (9) in the syringe body (3) that receives the active agent can be sealed, and a piston rod (21), which has a first end (23) that can be coupled to the stopper and an opposing second end (29). The syringe system is characterized by an aseptic secondary packaging (39) having an interior (41) for receiving the syringe (1).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61L 2/00 - Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lensesAccessories therefor
43.
DEVICE AND METHOD FOR MOUNTING A PHARMACEUTICAL APPLICATION AID
The invention relates to a device (1) for mounting a pharmaceutical application aid (51), particularly a pen. The device (1) is characterized by a holding device (3) for fixing a first housing sleeve (5) accommodating a pharmaceutical container, particularly a carpule, and by a stop (43) for delimiting a displacement of a second housing sleeve (35) relative to the first housing sleeve (5).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
44.
DEVICE AND METHOD FOR ASSEMBLY OF A PHARMACEUTICAL APPLICATION AID
A device (1) for assembly of a pharmaceutical application aid (51), particularly a pen, is proposed. The device (1) is characterized by a holding device (3) for fixation of a first housing sleeve (5) that accommodates a pharmaceutical container, particularly a carpule (23), and by a stop (43) for limiting a displacement of a second housing sleeve (35) relative to the first housing sleeve (5).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A syringe cylinder comprising an interior space, having a stopper that can be displaced in the interior space and delimits an active ingredient space, is proposed. The syringe cylinder is characterized by an indicator device biuniquely indicating a longitudinal movement of the stopper occurring in one direction.
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
The invention relates to a freeze drying receptacle (1) for receiving pharmaceutical containers (7) filled with a product to be frozen (9), said receptacle having at least one base body (3) with at least one receiving region (5). The receptacle is characterised in that a wall region (13) of the receiving region (5) preferably completely surrounds the product to be frozen (9) that is located in the container (7).
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
An X-ray device is proposed for examining syringe caps (3) that have a cannula (27), with an X-ray source (5), an X-ray detector (9), and with a holder (39) which holds the syringe cap (3) in the beam path (13) at an examination site (15). The X-ray device is characterized by the syringe cap (3) being arranged in the beam path (13) in such a way that its longitudinal axis (17) coincides with the main axis (19) of the beam path (13).
A61M 5/00 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests
A61M 5/34 - Constructions for connecting the needle
48.
DEVICE FOR CONTROLLING THE TEMPERATURE OF PRODUCTS TO BE FROZEN
The invention relates to a device (1) for controlling the temperature of products to be frozen during a freeze drying process. Said device (1) is characterised in that it contains at least one Peltier element (3).
F26B 5/06 - Drying solid materials or objects by processes not involving the application of heat by evaporation or sublimation of moisture under reduced pressure, e.g. in a vacuum the process involving freezing
The invention relates to a temperature control device (1) for pharmaceutical solution containers (13), comprising at least one wall section (3), into which a temperature-controlled medium can be introduced. The device is characterised in that it can be attached to and detached from the exterior of the solution container (13).
The invention relates to an attachment (1) for a syringe (3) or a cartridge, comprising a base body (7) and a sealing element (9) that can be inserted in the base body (7) and arranged in the region of an opening (11) of the syringe (3) or the cartridge. Said attachment is characterized in that at least one sealing element (9) comprises Teflon and/or PTFE and is elastically fastened in the attachment (1).
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
The invention relates to an attachment (1) or a cartridge comprising a sealing element (5) having an opening (9) for a medium located in the syringe or cartridge or to be introduced into the syringe (3) or cartridge. The attachment (1) is characterised by an actuating device (11) which, in a first functional position, exerts a force on the wall of the opening (9) in such a way that the opening (9) is closed, and leaves the opening (9) open in a second functional position.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
20 - Furniture and decorative products
40 - Treatment of materials; recycling, air and water treatment,
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Pharmaceutical preparations and medicines for use in the treatment of infections, cancer, depression, heart disease, vascular disease, intestinal disorder, lung and bronchial dysfunction, liver dysfunction, oral and laryngeal disease, optical and cranial disorders; solutions to be taken orally, sterile solutions in forms suitable for sale and/or application, injection solutions, all for use in the treatment of infections, cancer, depression, heart disease, vascular disease, intestinal disorder, lung and bronchial dysfunction, liver dysfunction, oral and laryngeal disease, optical and cranial disorders; eyedrops, contact lens solutions; non-impregnated cotton swabs for medical use; cotton swabs impregnated with alcohol, iodine, sterilizing agents and cleaning solutions for medical purposes; pre-moistened cotton swabs for medical purposes; plasters for skin wounds; medical injection systems, namely syringes and injection instruments, injectors (in particular pen systems), auto-injectors, and single-chamber and double-chamber disposable syringes; medicine containers of glass and/or plastic; syringe holders. (1) Filling of sterile solutions into containers, syringes and injection instruments; filling of pharmaceutical products of a liquid, semi-solid or solid kind into containers, syringes and injection instruments; development of injection syringes and instruments and of injectors and related packaging; chemical, physical and process-technological laboratory test services; laboratory research into chemical, physical and process engineering; performing microbiological tests and processes in the field of the sterility of pharmaceutical solutions, including for a fee for others
A syringe cylinder having an interior space (9) and a plug (11) which can be displaced in the interior space (9) and defines an active-substance space (13) is proposed. Said syringe cylinder is characterized by an indicating device (19) which clearly indicates a longitudinal movement of the plug (11) in one direction.
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
A syringe cylinder having an interior space (9) and a plug (11) which can be displaced in the interior space (9) and defines an active-substance space (13) is proposed. Said syringe cylinder is characterized by an indicating device (19) which clearly indicates a longitudinal movement of the plug (11) in one direction.
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
The invention proposes a syringe or carpoule having a cylinder (1), which encloses a cavity and comprises an end (3) which has access to the cavity, having a membrane (5), which seals off the access and has an insertion region (18) which can be pierced by a needle, having a two-part cap (15), which exhibits a predetermined breaking line (31) and spans the membrane, and having a covering device, which covers the insertion region (18) of the membrane (5) in a sterile manner and comprises a sealing region which spans the insertion region (18), and this syringe is distinguished in that the sealing region covers the insertion region (18) in a sterile manner irrespective of axial forces which can be applied in the region of the predetermined breaking line (31).
A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
The invention proposes a syringe or carpoule having a cylinder (1), which encloses a cavity and comprises an end (3) which has access to the cavity, having a membrane (5), which seals off the access and has an insertion region (18) which can be pierced by a needle, having a two-part cap (15), which exhibits a predetermined breaking line (31) and spans the membrane, and having a covering device, which covers the insertion region (18) of the membrane (5) in a sterile manner and comprises a sealing region which spans the insertion region (18), and this syringe is distinguished in that the sealing region covers the insertion region (18) in a sterile manner irrespective of axial forces which can be applied in the region of the predetermined breaking line (31).
A61J 1/00 - Containers specially adapted for medical or pharmaceutical purposes
A61M 5/24 - Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or cartridges, e.g. automatic
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
39 - Transport, packaging, storage and travel services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical preparations and medicines;solutions to be taken orally, sterile solutions in forms suitable for sale and/or application, injection solutions;eyedrops, contact lens solutions; swabs; plasters. Medical injection systems, namely syringes and injection instruments, injectors (in particular pen systems), auto-injectors, and single-chamber and double-chamber disposable syringes;medicine containers of glass and/or plastic;syringe holders. Filling of substances. Development of injection syringes and instruments and of injectors and related packaging;chemical, physical and process-technological laboratory tests and performing microbiological tests and processes, including for a fee for others.
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
39 - Transport, packaging, storage and travel services
42 - Scientific, technological and industrial services, research and design
Goods & Services
Pharmaceutical preparations and medicines; solutions to be taken orally, sterile solutions in forms suitable for sale and/or application, injection solutions; eyedrops, contact lens solutions; swabs; plasters. Medical injection systems, namely syringes and injection instruments, injectors (in particular pen systems), auto-injectors, and single-chamber and double-chamber disposable syringes; medicine containers of glass and/or plastic; syringe holders. Filling of substances. Development of injection syringes and instruments and of injectors and related packaging; chemical, physical and process-technological laboratory tests and performing microbiological tests and processes, including for a fee for others.
The invention relates to an attachment for a syringe or cartridge comprising a cannula. The attachment encompasses a sealing element that is sprayed onto the cannula.
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 5/34 - Constructions for connecting the needle
Attachment (1) for a syringe (5) or cartridge comprising a cannula. The attachment (1) encompasses a sealing element (17) that is sprayed onto the cannula.
A61M 5/32 - NeedlesDetails of needles pertaining to their connection with syringe or hubAccessories for bringing the needle into, or holding the needle on, the bodyDevices for protection of needles
A61M 5/34 - Constructions for connecting the needle
A syringe is proposed having a syringe cylinder (3), a closure plug (7) which can move in the syringe cylinder (3), and having a plunger rod (13) which interacts with said closure plug (7). Said syringe is distinguished by a safety device (19) which prevents the closure plug (7) from sliding back in the syringe cylinder (3) in every position which said closure plug (7) assumes in the syringe cylinder (3), and by a locking element (21) which acts on the plunger rod (13) in every position which said plunger rod (13) assumes in the syringe cylinder (3).
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A syringe with a syringe cylinder (3) and with a sealing plug (7) movable within the syringe cylinder (3) and with a plunger (13) cooperating with the same is provided. It is characterized by a safety device (19), which prevents the sliding back of the sealing plug (7) within the syringe cylinder (3) in any position the same assumes within the syringe cylinder (3), and by a locking element (21), which engages at the plunger (13) in any position the same assumes within the syringe cylinder (3).
A61M 5/315 - PistonsPiston-rodsGuiding, blocking or restricting the movement of the rodAppliances on the rod for facilitating dosing
A61M 5/50 - Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular wayAccessories therefor, e.g. filling or cleaning devices, arm rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
05 - Pharmaceutical, veterinary and sanitary products
10 - Medical apparatus and instruments
Goods & Services
(1) Medicinal syringes and injection instruments, medical syringes and injection instruments prefilled with pharmaceutical products capable of dissolution in solvents; accessories for the above wares, namely disinfecting swabs; parts for the aforementioned wares, namely rim caps, elastic sealing elements, protective caps, sealing washers.
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
21 - HouseHold or kitchen utensils, containers and materials; glassware; porcelain; earthenware
39 - Transport, packaging, storage and travel services
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Pharmaceutical products and medicaments, namely, orally administrable solutions, injectable solutions, eye drops, solutions for contact lenses, solids and semisolids capable of being dissolved in liquids and solvents for powders in ready-to-use form or capable of reconstitution; medical injection systems, namely, injection syringes, pen-type injectors, autoinjectors, disposable and reusable syringes, syringes prefilled with pharmaceutical products capable of dissolution in solvents, syringe holders, automatic hand washers, disposable cannulas, ampullae, vials, non-impregnated swabs, impregnated swabs, and bandages. (1) Production of injection syringes and instruments as well as injectors and corresponding packaging; laboratory research into chemical, physical and process engineering as well as the conduct of microbiological research and processes, including such work carried out for others for remuneration.
01 - Chemical and biological materials for industrial, scientific and agricultural use
03 - Cosmetics and toiletries; cleaning, bleaching, polishing and abrasive preparations
05 - Pharmaceutical, veterinary and sanitary products
09 - Scientific and electric apparatus and instruments
10 - Medical apparatus and instruments
21 - HouseHold or kitchen utensils, containers and materials; glassware; porcelain; earthenware
39 - Transport, packaging, storage and travel services
42 - Scientific, technological and industrial services, research and design
Goods & Services
(1) Pharmaceutical products and medicaments, namely, orally administrable solutions, injectable solutions, eye drops, solutions for contact lenses, solids and semisolids capable of being dissolved in liquids and solvents for powders in ready-to-use form or capable of reconstitution; medical injection systems, namely, injection syringes, pen-type injectors, autoinjectors, disposable and reusable syringes, syringes prefilled with pharmaceutical products capable of dissolution in solvents, syringe holders, automatic hand washers, disposable cannulas, ampullae, vials, non-impregnated swabs, impregnated swabs, and bandages. (1) Production of injection syringes and instruments as well as injectors and corresponding packaging; laboratory research into chemical, physical and process engineering as well as the conduct of microbiological research and processes, including such work carried out for others for remuneration.
