Oriental Yeast Co., Ltd.

Japan

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2023 8
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2021 6
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IPC Class
C12N 15/09 - Recombinant DNA-technology 12
C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells 8
A61K 38/00 - Medicinal preparations containing peptides 7
C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells 7
C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids 7
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NICE Class
01 - Chemical and biological materials for industrial, scientific and agricultural use 12
30 - Basic staples, tea, coffee, baked goods and confectionery 4
05 - Pharmaceutical, veterinary and sanitary products 2
29 - Meat, dairy products, prepared or preserved foods 2
31 - Agricultural products; live animals 2
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Status
Pending 10
Registered / In Force 85

1.

METHOD FOR DETERMINING IGA NEPHROPATHY

      
Application Number JP2024016523
Publication Number 2024/225457
Status In Force
Filing Date 2024-04-26
Publication Date 2024-10-31
Owner
  • ORIENTAL YEAST CO., LTD. (Japan)
  • FUJITA ACADEMY (Japan)
Inventor
  • Takahashi Kazuo
  • Ohyama Yukako
  • Enomoto Tetsuro
  • Yamamoto Keiji

Abstract

The present invention provides a method for determining the onset possibility or disease activity of IgA nephropathy by means of blood-mediated liquid biopsy, in addition to highly invasive renal biopsy and conventionally used proteinuria or hematuria. The present invention provides a method for determining the onset possibility or disease activity of IgA nephropathy in a test animal, the method comprising (a) a step for measuring an IgA nephropathy marker protein contained in an IgA immune complex in a blood sample collected from the test animal, and (b) a step for determining the onset possibility or disease activity of IgA nephropathy in the test animal on the basis of the amount of the IgA nephropathy marker protein measured in step (a), wherein the IgA nephropathy marker protein is a protein which is contained in the IgA immune complex, and with which the amount of the IgA nephropathy marker protein contained in the IgA immune complex in an IgA nephropathy patient group is greater than the amount contained in the IgA immune complex of a healthy subject group.

IPC Classes  ?

  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
  • G01N 33/564 - ImmunoassayBiospecific binding assayMaterials therefor for pre-existing immune complex or autoimmune disease

2.

URICASE ACTIVATOR AND URIC ACID MEASUREMENT REAGENT

      
Application Number 18264910
Status Pending
Filing Date 2021-02-10
First Publication Date 2024-02-22
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Ichimaru, Kenta
  • Matsukawa, Hirokazu
  • Miyachi, Mayu
  • Taketani, Yukiko
  • Ikeno, Chizuka
  • Sunahara, Yoshiko

Abstract

Provided are a uricase activator and a uricase activation method which are capable of highly activating uricase. Also provided are a uric acid measurement reagent and a uric acid measurement method which have a wide measurable concentration range. Further provided are a uricase activator comprising hydroxyisourate hydrolase, and a uric acid measurement reagent for use in measuring a uric acid concentration in a sample collected from a living body, comprising uricase and hydroxyisourate.

IPC Classes  ?

  • C12N 9/78 - Hydrolases (3.) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
  • C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase

3.

METHOD FOR PRODUCING PYRIDOXAMINE PHOSPHATE

      
Application Number JP2023019997
Publication Number 2023/234277
Status In Force
Filing Date 2023-05-30
Publication Date 2023-12-07
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Oba Takashi
  • Matsukawa Hirokazu
  • Sunahara Yoshiko
  • Kamata Miho

Abstract

Provided is a production method for obtaining pyridoxamine phosphate having high coenzyme activity with AST or ALT. For the production of pyridoxamine phosphate, pyridoxal kinase and pyridoxamine are brought into contact in the presence of adenosine triphosphate at a pyridoxamine concentration of 2 mM or more, and reacted until the percentage of pyridoxamine remaining is less than 5%.

IPC Classes  ?

  • C12P 17/12 - Nitrogen as only ring hetero atom containing a six-membered hetero ring
  • C12N 9/12 - Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
  • C12N 15/54 - Transferases (2)
  • C12Q 1/52 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving transferase involving transaminase

4.

COMPOUND COMPRISING BETA-NICOTINAMIDE MONONUCLEOTIDE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF, AND METHOD FOR EVALUATING QUALITY AND METHOD FOR ASSESSING ENZYMATIC REACTIVITY OF SAID COMPOUND

      
Application Number 17907346
Status Pending
Filing Date 2021-02-10
First Publication Date 2023-11-02
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Taketani, Yukiko
  • Matsukawa, Hirokazu
  • Sunahara, Yoshiko

Abstract

A compound includes β-nicotinamide mononucleotide or a pharmacologically acceptable salt thereof. A purity of the compound as measured through HPLC is 95% or higher. A reactivity of the compound with lactate dehydrogenase is 30 units or higher.

IPC Classes  ?

  • C07H 19/048 - Pyridine radicals
  • C12Q 1/32 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase involving dehydrogenase
  • B01D 15/08 - Selective adsorption, e.g. chromatography

5.

CEREAL FLOUR COMPOSITION AND DOUGH FOOD PRODUCT

      
Document Number 03235691
Status Pending
Filing Date 2023-01-23
Open to Public Date 2023-08-10
Owner
  • NISSHIN SEIFUN GROUP INC. (Japan)
  • NISSHIN FLOUR MILLING INC. (Japan)
  • NISSHIN SEIFUN WELNA INC. (Japan)
  • NISSHIN SEIFUN PREMIX INC. (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yoshida, Masashi
  • Shibamoto, Noriyuki
  • Nakamura, Kenji
  • Yoshimura, Nobuhito
  • Toyota, Hajime
  • Nomura, Kei
  • Ozawa, Keisuke
  • Ito, Koichi
  • Aita, Chihiro

Abstract

The present invention provides a cereal flour composition which contains a cereal flour and an enzyme belonging to the tannase family, and in which the tannase activity per 1 g of the cereal flour is 0.1 kU/g to 60 kU/g. The composition preferably includes, in terms of mass, 10 ppm to 10,000 ppm of the enzyme relative to the total amount of the cereal flour. The cereal flour preferably includes at least one selected from among whole-wheat flour, bran, and other cereal flours having an ash content of 0.7 mass% or higher. The ash content of the cereal flour is preferably 0.5 mass% or higher.

IPC Classes  ?

  • A23L 7/104 - Fermentation of farinaceous cereal or cereal materialAddition of enzymes or microorganisms
  • A23L 7/109 - Types of pasta, e.g. macaroni or noodles
  • A21D 2/26 - Proteins
  • A21D 8/04 - Methods for preparing doughTreating dough prior to baking treating dough with microorganisms or enzymes

6.

CEREAL FLOUR COMPOSITION AND DOUGH FOOD PRODUCT

      
Application Number JP2023001966
Publication Number 2023/149268
Status In Force
Filing Date 2023-01-23
Publication Date 2023-08-10
Owner
  • NISSHIN SEIFUN GROUP INC. (Japan)
  • NISSHIN FLOUR MILLING INC. (Japan)
  • NISSHIN SEIFUN WELNA INC. (Japan)
  • NISSHIN SEIFUN PREMIX INC. (Japan)
  • ORIENTAL YEAST CO.,LTD. (Japan)
Inventor
  • Yoshida, Masashi
  • Shibamoto, Noriyuki
  • Nakamura, Kenji
  • Yoshimura, Nobuhito
  • Toyota, Hajime
  • Nomura, Kei
  • Ozawa, Keisuke
  • Ito, Koichi
  • Aita, Chihiro

Abstract

The present invention provides a cereal flour composition which contains a cereal flour and an enzyme belonging to the tannase family, and in which the tannase activity per 1 g of the cereal flour is 0.1 kU/g to 60 kU/g. The composition preferably includes, in terms of mass, 10 ppm to 10,000 ppm of the enzyme relative to the total amount of the cereal flour. The cereal flour preferably includes at least one selected from among whole-wheat flour, bran, and other cereal flours having an ash content of 0.7 mass% or higher. The ash content of the cereal flour is preferably 0.5 mass% or higher.

IPC Classes  ?

  • A23L 7/104 - Fermentation of farinaceous cereal or cereal materialAddition of enzymes or microorganisms
  • A21D 2/26 - Proteins
  • A21D 8/04 - Methods for preparing doughTreating dough prior to baking treating dough with microorganisms or enzymes
  • A23L 7/109 - Types of pasta, e.g. macaroni or noodles

7.

METHOD AND COMPOSITION FOR STABILISING NICOTINAMIDE ADENINE DINUCLEOTIDE

      
Application Number JP2023002617
Publication Number 2023/145872
Status In Force
Filing Date 2023-01-27
Publication Date 2023-08-03
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Taketani Yukiko
  • Matsukawa Hirokazu
  • Sunahara Yoshiko

Abstract

Provided are a method and composition for stabilising nicotinamide adenine dinucleotide (NAD) in a biosample. A sample derived from a subject is brought into contact with nicotinamide and/or nicotinamide derivative to stabilise NAD in the sample.

IPC Classes  ?

  • C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

8.

STEM CELL MEDIUM AND STEM CELL CULTURING METHOD

      
Application Number 17920661
Status Pending
Filing Date 2021-04-05
First Publication Date 2023-05-11
Owner Oriental Yeast Co., Ltd. (Japan)
Inventor
  • Ga, Ayumi
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

A medium for stem cells according to the present invention contains at least one of carboxymethyl cellulose and polyvinylpyrrolidone as a water-soluble polymer. The content of carboxymethyl cellulose in the medium is preferably such that the final concentration thereof is 0.001 μg/mL to 1 mg/mL. The content of polyvinylpyrrolidone in the medium is preferably such that the final concentration thereof is 0.05 μg/mL to 2 mg/mL.

IPC Classes  ?

  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor

9.

CHROMOSOME-STABILIZING AGENT FOR STEM CELLS

      
Application Number 17907491
Status Pending
Filing Date 2021-03-25
First Publication Date 2023-04-20
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Ga, Ayumi
  • Kinose, Keita
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

The present invention provides a chromosome-stabilizing agent for stem cells containing a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, or a solvate thereof, as an active ingredient. The present invention also provides a culture method for stem cells, including culturing stem cells in a culture medium containing a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, or a solvate thereof.

IPC Classes  ?

10.

AGENT FOR ACCELERATING GROWTH OF PLURIPOTENT STEM CELLS

      
Application Number 18064441
Status Pending
Filing Date 2022-12-12
First Publication Date 2023-04-13
Owner Oriental Yeast Co., Ltd. (Japan)
Inventor
  • Nojima, Jun
  • Matsuo, Hidenori
  • Furuya, Yuriko
  • Yasuda, Hisataka

Abstract

An object of the present invention is to provide a material capable of further accelerating growth of pluripotent stem cells, such as pluripotent stem cells, without impairing pluripotency thereof. In other words, the invention is an agent for accelerating growth of pluripotent stem cells, containing a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, and a solvate thereof as an active ingredient; and is a method for culturing pluripotent stem cells, including culturing pluripotent stem cells in a culture medium that contains a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, and a solvate thereof.

IPC Classes  ?

11.

METHOD FOR KEEPING QUALITIES OF COOKED RICE AND METHOD FOR PRODUCING COOKED RICE

      
Application Number 17770920
Status Pending
Filing Date 2020-10-14
First Publication Date 2022-11-17
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Takahashi, Takayasu
  • Kikuta, Kosuke
  • Yamada, Shigeru

Abstract

Provided are a method for keeping qualities of cooked rice and a method for producing cooked rice, including a step of bringing a polyvalent cation-containing liquid into contact with rice at any timing between before and after rice boiling or rice steaming, and a step of bringing an alginate-containing liquid into contact with the rice that contains a polyvalent cation and has been boiled or steamed.

IPC Classes  ?

  • A23L 7/196 - Products in which the original granular shape is maintained, e.g. parboiled rice

12.

MatriCOAT

      
Application Number 018783802
Status Registered
Filing Date 2022-10-25
Registration Date 2023-03-02
Owner ORIENTAL YEAST CO., LTD. (Japan)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Chemical test reagents for cell and microbiological research use, other than for medical and veterinary purposes.

13.

URICASE ACTIVATOR AND URIC ACID MEASUREMENT REAGENT

      
Document Number 03211023
Status Pending
Filing Date 2021-02-10
Open to Public Date 2022-08-18
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Ichimaru, Kenta
  • Matsukawa, Hirokazu
  • Miyachi, Mayu
  • Taketani, Yukiko
  • Ikeno, Chizuka
  • Sunahara, Yoshiko

Abstract

Provided are a uricase activator capable of high activation of uricase and a uricase activation method. Provided are a uric acid measurement reagent having a wide measurable concentration range and a uric acid measurement method. Provided are: a uricase activator that includes hydroxyisourate hydrolase; and a uric acid measurement reagent to be used to measure the uric acid concentration in a sample collected from a living organism, the uric acid measurement reagent including uricase and hydroxyisouric acid.

IPC Classes  ?

  • C12N 9/14 - Hydrolases (3.)
  • C12N 9/06 - Oxidoreductases (1.), e.g. luciferase acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
  • C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
  • C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
  • C12N 15/55 - Hydrolases (3)

14.

URICASE ACTIVATOR AND URIC ACID MEASUREMENT REAGENT

      
Application Number JP2021004869
Publication Number 2022/172343
Status In Force
Filing Date 2021-02-10
Publication Date 2022-08-18
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Ichimaru Kenta
  • Matsukawa Hirokazu
  • Miyachi Mayu
  • Taketani Yukiko
  • Ikeno Chizuka
  • Sunahara Yoshiko

Abstract

Provided are a uricase activator capable of high activation of uricase and a uricase activation method. Provided are a uric acid measurement reagent having a wide measurable concentration range and a uric acid measurement method. Provided are: a uricase activator that includes hydroxyisourate hydrolase; and a uric acid measurement reagent to be used to measure the uric acid concentration in a sample collected from a living organism, the uric acid measurement reagent including uricase and hydroxyisouric acid.

IPC Classes  ?

  • C12N 15/55 - Hydrolases (3)
  • C12Q 1/26 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving oxidoreductase
  • C12Q 1/34 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving hydrolase
  • C12N 9/06 - Oxidoreductases (1.), e.g. luciferase acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
  • C12N 9/14 - Hydrolases (3.)
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

15.

STEM CELL MEDIUM AND STEM CELL CULTURING METHOD

      
Application Number JP2021014552
Publication Number 2021/220731
Status In Force
Filing Date 2021-04-05
Publication Date 2021-11-04
Owner ORIENTAL YEAST CO.,LTD. (Japan)
Inventor
  • Ga, Ayumi
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

The stem cell medium according to the present invention contains, as a water soluble polymer compound, carboxymethyl cellulose and/or polyvinyl pyrrolidone. The added amount of carboxymethyl cellulose in the medium is preferably 0.001 µg/mL to 1 mg/mL in terms of the final concentration. Further, the added amount of polyvinyl pyrrolidone in the medium is preferably 0.05 µg/mL to 2 mg/mL in terms of the final concentration.

IPC Classes  ?

  • C12N 1/00 - Microorganisms, e.g. protozoaCompositions thereofProcesses of propagating, maintaining or preserving microorganisms or compositions thereofProcesses of preparing or isolating a composition containing a microorganismCulture media therefor
  • C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
  • C12N 5/074 - Adult stem cells
  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • C12N 5/0789 - Stem cellsMultipotent progenitor cells
  • C12N 5/0797 - Stem cellsProgenitor cells
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells

16.

STABILIZER FOR STEM CELL CHROMOSOMES

      
Application Number JP2021012557
Publication Number 2021/200545
Status In Force
Filing Date 2021-03-25
Publication Date 2021-10-07
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Ga Ayumi
  • Kinose Keita
  • Tomimori Yoshiya
  • Yasuda Hisataka

Abstract

The present invention provides: a stabilizer for stem cell chromosomes, said stabilizer being characterized by comprising, as an active ingredient, β-nicotinamide mononucleotide, a pharmacologically acceptable salt thereof or a solvate of the same; and a method for culturing stem cells, said method being characterized by comprising culturing pluripotent stem cells in a culture medium containing β-nicotinamide mononucleotide, a pharmacologically acceptable salt thereof or a solvate of the same.

IPC Classes  ?

  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
  • C12N 5/0789 - Stem cellsMultipotent progenitor cells
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms

17.

COMPOUND COMPRISING β-NICOTINAMIDE MONONUCLEOTIDE OR PHARMACOLOGICALLY ACCEPTABLE SALT THEREOF, AND METHOD FOR EVALUATING QUALITY AND METHOD FOR ASSESSING ENZYMATIC REACTIVITY OF SAID COMPOUND

      
Application Number JP2021004912
Publication Number 2021/192683
Status In Force
Filing Date 2021-02-10
Publication Date 2021-09-30
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Taketani, Yukiko
  • Matsukawa, Hirokazu
  • Sunahara, Yoshiko

Abstract

A compound comprising β-nicotinamide mononucleotide or a pharmacologically acceptable salt thereof, wherein the purity measured by HPLC is 95% or higher, and the reactivity to lactate dehydrogenase is 30 U or higher.

IPC Classes  ?

  • C07H 19/048 - Pyridine radicals
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals

18.

METHOD FOR KEEPING QUALITIES OF COOKED RICE AND METHOD FOR PRODUCING COOKED RICE

      
Application Number JP2020038815
Publication Number 2021/079805
Status In Force
Filing Date 2020-10-14
Publication Date 2021-04-29
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Takahashi, Takayasu
  • Kikuta, Kosuke
  • Yamada, Shigeru

Abstract

A method for keeping the qualities of cooked rice and a method for producing cooked rice, each method comprising a step for contacting rice with a liquid containing a polyvalent cation at any time from before cooking or steaming the rice to thereafter and a step for contacting the polyvalent cation-containing rice, which has been cooked or steamed, with a liquid containing an alginic acid salt.

IPC Classes  ?

19.

METHOD FOR KEEPING QUALITIES OF COOKED RICE AND METHOD FOR PRODUCING COOKED RICE

      
Document Number 03158629
Status Pending
Filing Date 2020-10-14
Open to Public Date 2021-04-29
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Takahashi, Takayasu
  • Kikuta, Kosuke
  • Yamada, Shigeru

Abstract

A method for keeping the qualities of cooked rice and a method for producing cooked rice, each method comprising a step for contacting rice with a liquid containing a polyvalent cation at any time from before cooking or steaming the rice to thereafter and a step for contacting the polyvalent cation-containing rice, which has been cooked or steamed, with a liquid containing an alginic acid salt.

IPC Classes  ?

  • A23L 7/196 - Products in which the original granular shape is maintained, e.g. parboiled rice
  • A23L 7/10 - Cereal-derived products
  • A23L 29/256 - Foods or foodstuffs containing additivesPreparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan

20.

Pluripotent stem cell differentiation-promoting agent

      
Application Number 16981628
Grant Number 11814652
Status In Force
Filing Date 2019-03-20
First Publication Date 2021-01-28
Grant Date 2023-11-14
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Matsuo, Hidenori
  • Ga, Ayumi
  • Yamada, Munehiro
  • Tomimori, Yoshiya

Abstract

The object of the present invention is to provide a material for efficiently obtaining differentiated cells from pluripotent stem cells. That is, the present invention relates to a pluripotent stem cell differentiation-promoting agent containing, as an active ingredient, a β-nicotinamide mononucleotide or a pharmacologically acceptable salt thereof, and a solvate thereof, and a method for differentiating pluripotent stem cells, including culturing pluripotent stern cells in a culture medium containing a β-nicotinamide mononucleotide or a pharmacologically acceptable salt thereof, and a solvate thereof.

IPC Classes  ?

21.

FRESHLON GOHAN

      
Application Number 206620200
Status Pending
Filing Date 2020-11-25
Owner Oriental Yeast Co., Ltd. (Japan)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

(1) Chemical additives for use in the manufacture of food, namely, quality improver for rice; Chemical additives for use in the manufacture of food, namely, quality improving agent; Food preserving chemicals, namely, shelf life improver

22.

Skin pigmentation inhibitor

      
Application Number 16484004
Grant Number 11219632
Status In Force
Filing Date 2018-02-08
First Publication Date 2020-01-16
Grant Date 2022-01-11
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Shinzato, Tatsuya
  • Enomoto, Tetsuro
  • Yasuda, Hisataka
  • Arai, Hideo

Abstract

An object of the present invention is to provide a material which can be safely ingested and which inhibits skin pigmentation. Therefore, the invention is a skin pigmentation inhibitor, containing a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof; and a solvate thereof as an active ingredient; a health supplement which contains the skin pigmentation inhibitor and is ingested to inhibit skin pigmentation; and a method for inhibiting skin pigmentation, including ingesting the skin pigmentation inhibitor.

IPC Classes  ?

  • A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
  • A61K 8/60 - SugarsDerivatives thereof
  • A61K 9/00 - Medicinal preparations characterised by special physical form
  • A61P 17/00 - Drugs for dermatological disorders
  • A61Q 19/02 - Preparations for care of the skin for chemically bleaching or whitening the skin

23.

Agent for accelerating growth of pluripotent stem cells

      
Application Number 16481760
Grant Number 11634690
Status In Force
Filing Date 2018-01-31
First Publication Date 2019-12-26
Grant Date 2023-04-25
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Nojima, Jun
  • Matsuo, Hidenori
  • Furuya, Yuriko
  • Yasuda, Hisataka

Abstract

An object of the present invention is to provide a material capable of further accelerating growth of pluripotent stem cells, such as pluripotent stem cells, without impairing pluripotency thereof. In other words, the invention is an agent for accelerating growth of pluripotent stem cells, containing a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, and a solvate thereof as an active ingredient; and is a method for culturing pluripotent stem cells, including culturing pluripotent stem cells in a culture medium that contains a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, and a solvate thereof.

IPC Classes  ?

24.

DIFFERENTIATION PROMOTER FOR PLURIPOTENT STEM CELLS

      
Application Number JP2019011827
Publication Number 2019/182044
Status In Force
Filing Date 2019-03-20
Publication Date 2019-09-26
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Matsuo Hidenori
  • Ga Ayumi
  • Yamada Munehiro
  • Tomimori Yoshiya

Abstract

The present invention addresses the problem of providing a material for efficiently obtaining differentiated cells from pluripotent stem cells. Specifically, the present invention provides: a differentiation promoter for pluripotent stem cells that is characterized by having, as an active ingredient, β-nicotinamide mononucleotide, a pharmacologically acceptable salt thereof, or a solvate of either; and a method for causing pluripotent stem cells to differentiate that is characterized in that pluripotent stem cells are cultivated in a culture medium containing β-nicotinamide mononucleotide, a pharmacologically acceptable salt thereof, or a solvate of either.

IPC Classes  ?

  • C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
  • C12N 1/38 - Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factorsStimulation of growth by removal of a chemical compound
  • C12N 5/074 - Adult stem cells
  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • C12N 5/0789 - Stem cellsMultipotent progenitor cells
  • C12N 5/0797 - Stem cellsProgenitor cells
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom

25.

OSTEOGENESIS PROMOTER AND PROMOTION METHOD

      
Application Number JP2018024873
Publication Number 2019/004444
Status In Force
Filing Date 2018-06-29
Publication Date 2019-01-03
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Furuya Yuriko
  • Yasuda Hisataka

Abstract

Provided is an osteogenesis promoter for promoting the differentiation of osteoblast precursor cells into osteoblast cells, and the calcification of the osteoblast cells. The osteogenesis promoter includes, as an active ingredient, a substance which bonds to a TNF-related apoptosis-inducing ligand (TRAIL) receptor, said substance being a TRAIL or anti-TRAIL receptor antibody.

IPC Classes  ?

  • A61K 38/18 - Growth factorsGrowth regulators
  • A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
  • A61P 3/14 - Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
  • A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
  • A61P 19/10 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • C07K 14/51 - Bone morphogenic factorOsteogeninOsteogenic factorBone-inducing factor
  • C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
  • C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
  • C12P 21/08 - Monoclonal antibodies

26.

SKIN PIGMENTATION INHIBITOR

      
Application Number JP2018004459
Publication Number 2018/147385
Status In Force
Filing Date 2018-02-08
Publication Date 2018-08-16
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Shinzato Tatsuya
  • Enomoto Tetsuro
  • Yasuda Hisataka
  • Arai Hideo

Abstract

The present invention addresses the problem of providing a material that can be safely ingested and suppresses skin pigmentation. In other words, the present invention provides: a skin pigmentation inhibitor characterized in that a β-nicotinamide mononucleotide or a pharmaceutically acceptable salt thereof, or a solvate of these substances serves as an active ingredient thereof; a health supplement that contains said skin pigmentation inhibitor and is ingested in order to suppress skin pigmentation; and a method for suppressing skin pigmentation, said method including ingesting said skin pigmentation inhibitor.

IPC Classes  ?

  • A61K 31/706 - Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
  • A61K 8/60 - SugarsDerivatives thereof
  • A61P 17/00 - Drugs for dermatological disorders
  • A61Q 19/02 - Preparations for care of the skin for chemically bleaching or whitening the skin

27.

AGENT FOR ACCELERATING GROWTH OF STEM CELLS WITH DIFFERENTIATION POTENTIAL

      
Application Number JP2018003172
Publication Number 2018/143258
Status In Force
Filing Date 2018-01-31
Publication Date 2018-08-09
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Nojima Jun
  • Matsuo Hidenori
  • Furuya Yuriko
  • Yasuda Hisataka

Abstract

The present invention addresses the problem of providing a material for further accelerating the growth of stem cells with differentiation potential, such as pluripotent stem cells, without impairing the differentiation potential thereof. That is, the present invention pertains to: an agent for accelerating the growth of stem cells with differentiation potential, characterized by containing, as active ingredients, β-nicotinamide mononucleotide (β-NMN) or a pharmaceutically acceptable salt thereof, and a solvate thereof; and a differentiation potential-having stem cells culturing method, characterized by culturing stem cells with differentiation potential in a culture medium containing β-nicotinamide mononucleotide (β-NMN) or a pharmaceutically acceptable salt thereof, and a solvate thereof.

IPC Classes  ?

  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12N 15/09 - Recombinant DNA-technology

28.

METHOD FOR PRODUCING CITRUS FRUIT FLESH

      
Application Number JP2017013213
Publication Number 2017/170853
Status In Force
Filing Date 2017-03-30
Publication Date 2017-10-05
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Suzuki, Motoomi
  • Yamanaka, Yuri
  • Takahashi, Takayasu

Abstract

The present invention is a method for producing citrus fruit flesh comprising: a step for (a) heat treatment and/or (b) organic acid treatment of the fruit of a citrus fruit that has at least an albedo and segment membranes; a step for separating the fruit into multiple or single sections; and a step for bringing the fruit into contact with at least one kind of enzyme selected from a group consisting of cellulase enzymes, pectinase enzymes and hemicellulase enzymes.

IPC Classes  ?

  • A23N 7/01 - Peeling vegetables or fruit using chemical substances, e.g. lye
  • A23L 19/00 - Products from fruits or vegetablesPreparation or treatment thereof

29.

ORICOBO

      
Application Number 1339879
Status Registered
Filing Date 2016-10-27
Registration Date 2016-10-27
Owner ORIENTAL YEAST CO., LTD. (Japan)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 30 - Basic staples, tea, coffee, baked goods and confectionery

Goods & Services

Chemicals; chemicals for use in food industry; conditioning agents for food; chemical agents for improving the quality of bread and cake; conditioning agents for confectionery and bread; chemical agents for improving shelf life of foodstuffs; chemical agents for improving quality of foodstuffs; bacteriostats for the food industry; lye water, lye powder(Kansui, food additive for Chinese noodles); chemical agents for softening pounded rice cakes; enzymes; lactic acid bacteria for use in food manufacture. Yeast; fresh yeast; dry yeast; flour paste (confectionery and bakery creams made of wheat flour and starch as main ingredients); flour paste in powder form; custard powder; fermented flavor liquid; pre-ferment; sourdough powder; baking powder; chemical leaveners; mayonnaise; salad dressings; ketchup [sauce]; pizza sauce; yeast extract; malt extract for food; brown rice (prepared); sprouted rice (prepared); roasted rye.

30.

POWDER COMPOSITION FOR PREPARING FLOUR PASTE

      
Application Number JP2014077319
Publication Number 2016/059669
Status In Force
Filing Date 2014-10-14
Publication Date 2016-04-21
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Kojima, Seizo
  • Nomoto, Hiroyuki
  • Nakabayashi, Hideo

Abstract

The purpose of the present invention is to improve the storage stability, heat resistance and long-term stability of a flour paste and to reduce the cost required for the transportation, storage and production of a flour paste. The present invention provides a powder composition for preparing a flour paste, said powder composition comprising predetermined amounts of a modified starch, an unmodified starch, a milk whey protein and a thickening agent.

IPC Classes  ?

  • A23L 1/19 - Cream substitutes
  • A21D 13/00 - Finished or partly finished bakery products
  • A23G 3/00 - SweetmeatsConfectioneryMarzipanCoated or filled products
  • A23G 3/34 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof

31.

ORIENTAL YEAST CO.,LTD.

      
Application Number 1287507
Status Registered
Filing Date 2015-10-29
Registration Date 2015-10-29
Owner ORIENTAL YEAST CO., LTD. (Japan)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 30 - Basic staples, tea, coffee, baked goods and confectionery
  • 31 - Agricultural products; live animals

Goods & Services

Chemicals for use in food and beverages industry; conditioning agents for food; chemical agents for conditioning quality of foodstuffs; chemical agents for improving shelf life of foodstuffs; chemical agents for improving quality of foodstuffs; bacteriostats for use in industry; lye water (Kansui, food additive for Chinese noodles); chemical agents for softening foodstuffs; biochemistry reagent kit including chemical substances and biochemical other than for medical and veterinary use; enzymes; medium for microorganisms or medium for cell cultures other than for medical and veterinary use; stem cells other than for medical or veterinary purpose; protein; other chemicals. Confectionery and bakery creams made of wheat flour and starch as main ingredients; flour paste in powder form (confectionery and bakery creams made of wheat flour and starch as main ingredients); flour paste (confectionery and bakery creams made of wheat flour and starch as main ingredients); confectionery; bread and buns; sandwiches; Chinese buns; hamburger sandwiches; pizzas; hot dogs [sandwiches]; meat pies; pizza sauce; powdered mayonnaise mixes; other seasonings [other than spices]; brown rice (prepared); sprouted rice (prepared); processed grains; Chinese stuffed dumplings; Chinese steamed dumplings; sushi; fried balls of batter mix with small pieces of octopus [Takoyaki]; boxed lunches consisting of rice, with added meat, fish or vegetables; ravioli; yeast extract; pre-ferment; yeast powder; koji [fermented malted rice]; yeast; baking powder; malt extract for food; custard powder; instant confectionery mixes; fermented flavor liquid; food flavorings other than food flavorings prepared from essential oils; roasted rye; rice; husked oats; husked barley; flour mixes; flour. Foodstuffs for animals; live animals; laboratory animals.

32.

BAKING POWDER, METHOD FOR MANUFACTURING SAME, AND FOOD USING BAKING POWDER

      
Application Number JP2014069459
Publication Number 2016/013071
Status In Force
Filing Date 2014-07-23
Publication Date 2016-01-28
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Arai Tsutomu
  • Shinoda Eiji
  • Chiba Hitoshi

Abstract

The purpose of the present invention is to provide a baking powder having excellent delayed effectiveness. Provided is a baking powder comprising sodium bicarbonate and acidic agents, said acidic agents having a median diameter of 100 μm or more and being coated with a fat having a melting point of 55-75oC, wherein: the acidic agents consist of one or more kinds of acidic agents having a median diameter of 100 μm or more and one or more kinds of acidic agents having a median diameter of less than 100 μm; and one or more kinds of acidic agents having a median diameter of 100 μm or more are surface-coated with the fat containing one or more kinds of acidic agents having a median diameter of less than 100 μm.

IPC Classes  ?

  • A21D 2/00 - Treatment of flour or dough by adding materials thereto before or during baking

33.

AGENT FOR IMPROVING GLUCOSE TOLERANCE DISORDER

      
Application Number JP2014066007
Publication Number 2015/193962
Status In Force
Filing Date 2014-06-17
Publication Date 2015-12-23
Owner
  • NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (Japan)
  • NISSHIN SEIFUN GROUP INC. (Japan)
  • ORIENTAL YEAST CO.,LTD. (Japan)
Inventor
  • Oishi, Katsutaka
  • Itoh, Nanako
  • Yamamoto, Saori
  • Fukudome, Shin-Ichi
  • Kikuchi, Yosuke
  • Okita, Kimiko

Abstract

An agent for improving glucose tolerance disorder that comprises, as an active ingredient, partition chromatography peak components of an alcoholic extract of gramineous plant seeds, said peak components preferably comprising an alkyl resorcinol (AR) mixture containing multiple kinds of alkyl resorcinols. This mixture preferably contains an AR of general formula (I) wherein R1 is a saturated or unsaturated alkyl group having 15 carbon atoms, an AR of general formula (I) wherein R1 is a saturated or unsaturated alkyl group having 17 carbon atoms, an AR of general formula (I) wherein R1 is a saturated or unsaturated alkyl group having 19 carbon atoms, an AR of general formula (I) wherein R1 is a saturated or unsaturated alkyl group having 21 carbon atoms, an AR of general formula (I) wherein R1 is a saturated or unsaturated alkyl group having 23 carbon atoms, and an AR of general formula (I) wherein R1 is a saturated or unsaturated alkyl group having 25 carbon atoms, each in a specific amount. In general formula (I): R1 represents a saturated or unsaturated alkyl group having 15-25 carbon atoms; and R2 represents a hydrogen atom or a methyl group.

IPC Classes  ?

  • A61K 36/899 - Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
  • A23K 1/16 - supplemented with accessory food factors; Salt blocks
  • A23K 1/18 - specially adapted for particular animals
  • A23L 1/30 - containing additives (A23L 1/308 takes precedence);;
  • A61K 31/047 - Hydroxy compounds, e.g. alcoholsSalts thereof, e.g. alcoholates having two or more hydroxy groups, e.g. sorbitol
  • A61P 3/10 - Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

34.

FRESHLON

      
Application Number 1274854
Status Registered
Filing Date 2015-07-27
Registration Date 2015-07-27
Owner ORIENTAL YEAST CO., LTD. (Japan)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Chemicals; chemicals for use in food industry; chemical agents for improving shelf life of foodstuffs; chemical agents for improving quality of foodstuffs.

35.

Method of regulating circadian rhythm, and method of preparing circadian rhythm regulatory agent

      
Application Number 14676265
Grant Number 09737494
Status In Force
Filing Date 2015-04-01
First Publication Date 2015-10-29
Grant Date 2017-08-22
Owner
  • NAT'L INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE & TECHNOLOGY (Japan)
  • NISSHIN SEIFUN GROUP INC. (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Oishi, Katsutaka
  • Miyazaki, Koyomi
  • Onishi, Yoshiaki
  • Tomita, Tatsunosuke
  • Itoh, Nanako
  • Fukudome, Shinichi
  • Tanaka, Keiko
  • Kikuchi, Yosuke
  • Kasuya, Kenji

Abstract

1 is preferably a saturated or unsaturated alkyl group having 15 to 27 carbon atoms. [Chem. 1]

IPC Classes  ?

36.

FRESHLON

      
Application Number 174421700
Status Registered
Filing Date 2015-09-01
Registration Date 2017-09-14
Owner Oriental Yeast Co., Ltd. (Japan)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

(1) Chemical products for the fresh-keeping of food; Chemical preparations for preserving foodstuffs

37.

FRESHLON

      
Serial Number 79176886
Status Registered
Filing Date 2015-07-27
Registration Date 2016-06-21
Owner ORIENTAL YEAST CO., LTD. (Japan)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Chemicals for use in industry; chemicals for use in food industry; chemical agents for improving shelf life of foodstuffs; chemical agents for improving quality of foodstuffs

38.

FORMATE DEHYDROGENASE AND USE THEREOF

      
Application Number JP2014078442
Publication Number 2015/064517
Status In Force
Filing Date 2014-10-27
Publication Date 2015-05-07
Owner
  • GIFU UNIVERSITY (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Nakagawa Tomoyuki
  • Mizuguchi Mitsuhiro
  • Sawano Tatsuya

Abstract

The purpose of the present invention is to provide: a formate dehydrogenase having a high specific activity; and a method for producing a formate dehydrogenase with high efficiency without using methanol. The present invention relates to: a novel formate dehydrogenase; a gene encoding the formate dehydrogenase; a method for producing the formate dehydrogenase; and a method for regenerating a coenzyme using the formate dehydrogenase.

IPC Classes  ?

  • C12N 15/09 - Recombinant DNA-technology
  • C12N 1/15 - Fungi Culture media therefor modified by introduction of foreign genetic material
  • C12N 1/19 - YeastsCulture media therefor modified by introduction of foreign genetic material
  • C12N 1/21 - BacteriaCulture media therefor modified by introduction of foreign genetic material
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12N 9/04 - Oxidoreductases (1.), e.g. luciferase acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
  • C12P 19/38 - Nucleosides

39.

LABES

      
Application Number 1228765
Status Registered
Filing Date 2014-07-28
Registration Date 2014-07-28
Owner ORIENTAL YEAST CO., LTD. (Japan)
NICE Classes  ?
  • 31 - Agricultural products; live animals
  • 44 - Medical, veterinary, hygienic and cosmetic services; agriculture, horticulture and forestry services

Goods & Services

Experimental animals (laboratory animals); live animals; foodstuffs for animals. Breeding services for animals and providing information on the same.

40.

YEAST EXTRACT CONTAINING COPPER, METHOD FOR MANUFACTURING SAME, FOOD PRODUCT, AND GREEN COLOR PRESERVING AND RESTORING AGENT FOR VEGETABLES

      
Application Number JP2014058404
Publication Number 2014/162936
Status In Force
Filing Date 2014-03-26
Publication Date 2014-10-09
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yukawa, Mai
  • Kawai, Ryo
  • Wada, Kuniko
  • Yamada, Shigeru
  • Oka, Osamu

Abstract

Provided is a method for manufacturing a yeast extract containing copper includes an extraction step wherein yeast containing copper is suspended in a solution that contains an amino acid or a salt thereof and the solid components and liquid components of the suspension obtained are separated with the amino acid or salt thereof being water-soluble. Also provided are a yeast extract containing copper, a food product, and a green color preserving and restoring agent for vegetables.

IPC Classes  ?

  • A23L 1/28 - Edible extracts or preparations of fungi (for medicinal purposes A61K)
  • A23L 1/272 - Retaining or modifying natural colour by use of additives, e.g. optical brighteners (A23L 1/275 takes precedence);;

41.

BREAD QUALITY IMPROVING AGENT

      
Application Number JP2014058131
Publication Number 2014/157111
Status In Force
Filing Date 2014-03-24
Publication Date 2014-10-02
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor Kondo, Yasufumi

Abstract

Problem: To provide a preparation capable of easily and efficiently improving the quality of filling-containing breads, in particular, filling-containing breads in which the amount of filling is comparatively large and/or the water content in the filling is high, and a production method, and the like, for breads using the preparation. Solution: By adding and mixing an alginate ester, powdered egg yolk, and modified starch in bread dough for filling-containing breads, the migration of moisture from the filling to the bread part is suppressed and sogginess of the bread in such breads is suppressed even if there is a migration of moisture, peeling of the bread crust is suppressed, sticking of the bread is suppressed, and the bread is imparted with a flaky texture, as a result of which the bread quality can be improved.

IPC Classes  ?

  • A21D 2/08 - Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
  • A21D 2/18 - Carbohydrates
  • A21D 2/34 - Animal material
  • A21D 13/00 - Finished or partly finished bakery products

42.

BREAD QUALITY IMPROVING AGENT AND PRODUCTION METHOD FOR BREADS

      
Application Number JP2014059014
Publication Number 2014/157577
Status In Force
Filing Date 2014-03-27
Publication Date 2014-10-02
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Kondo, Yasufumi
  • Watanabe, Gen

Abstract

Problem: To provide a bread quality improving agent suitable for frozen dough with which it is possible to prepare breads from frozen bread dough without a decrease in the quality (for example, the bread volume, bread height, specific volume, crust quality, etc.) of the breads, and a production method, and the like, for breads using the improving agent. Solution: A bread quality improving agent for frozen dough is used which includes transglutaminase, L-ascorbic acid, and a bread emulsifier. In addition, bread dough is prepared combined with the bread quality improving agent for frozen dough, the bread dough is frozen following any of the steps of primary fermentation, shaping, and final fermentation, and breads are produced therefrom according to conventional methods.

IPC Classes  ?

  • A21D 8/04 - Methods for preparing doughTreating dough prior to baking treating dough with microorganisms or enzymes
  • A21D 2/16 - Fatty acid esters
  • A21D 2/22 - Ascorbic acid
  • A21D 13/00 - Finished or partly finished bakery products

43.

High-zinc yeast extract, method of producing same and agents and foods containing same

      
Application Number 14243609
Grant Number 09185926
Status In Force
Filing Date 2014-04-02
First Publication Date 2014-07-31
Grant Date 2015-11-17
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Kodoi, Rie
  • Takahashi, Takayasu
  • Oka, Osamu
  • Urasaki, Hiromi

Abstract

A method for producing a high-zinc-content yeast extract, including extracting the high-zinc-content yeast extract by suspending zinc-containing yeast into a solution containing a carboxylic acid, a carboxylic acid salt, or both thereof to thereby obtain a suspension liquid, and separating a solid component and a liquid component of the suspension liquid; the high-zinc-content yeast extract; food; and an agent for maintaining and restoring a green color of vegetables.

IPC Classes  ?

  • A23L 1/28 - Edible extracts or preparations of fungi (for medicinal purposes A61K)
  • A23L 1/272 - Retaining or modifying natural colour by use of additives, e.g. optical brighteners (A23L 1/275 takes precedence);;
  • A61K 36/064 - Saccharomycetales, e.g. baker's yeast
  • A23L 1/30 - containing additives (A23L 1/308 takes precedence);;
  • A23L 1/304 - Inorganic salts, minerals, trace elements
  • A23L 1/212 - Preparation of fruits or vegetables (of pulse A23L 1/20; treating harvested fruit or vegetables in bulk A23N)
  • A23L 3/3508 - Organic compounds containing oxygen containing carboxyl groups
  • A23L 3/3571 - Microorganisms; Enzymes
  • A23B 7/154 - Organic compoundsMicroorganismsEnzymes

44.

HIGH-IRON-CONTENT YEAST EXTRACT, METHOD FOR PRODUCING SAME, AND FOOD PRODUCT

      
Application Number JP2013073756
Publication Number 2014/042046
Status In Force
Filing Date 2013-09-04
Publication Date 2014-03-20
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yukawa, Mai
  • Kodoi, Rie
  • Oka, Osamu

Abstract

Provided are: a method that is for producing a high-iron-content yeast extract and that contains an extraction step for suspending iron-containing yeast in a solution containing a carboxylic acid and/or a carboxylate, and separating the solid component and liquid component of the obtained suspension; a high-iron-content yeast extract; and a food product.

IPC Classes  ?

  • C12N 1/16 - YeastsCulture media therefor
  • A23L 1/30 - containing additives (A23L 1/308 takes precedence);;

45.

AGENT FOR PRESERVING QUALITY OF PEELED AND/OR CUT VEGETABLE OR FRUIT AND/OR SEAFOOD

      
Application Number JP2013070248
Publication Number 2014/017616
Status In Force
Filing Date 2013-07-25
Publication Date 2014-01-30
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Urasaki, Hiromi
  • Oka, Osamu
  • Onda, Masaru

Abstract

[Problem] To provide: a novel quality-preserving agent which can preserve the quality of a peeled and/or cut vegetable or fruit or a seafood during storage in a simple manner and effectively and is highly safe; and others. [Solution] The quality-preserving agent contains two components, i.e., sodium acetate and α-lipoic acid, as active ingredients. The quality-preserving agent can prevent the discoloration, brownish discoloration or the like of a peeled and/or cut vegetable or fruit or a seafood during chilled storage and ambient-temperature storage of the vegetable or fruit or the seafood, can improve the shelf life of the vegetable or fruit or the seafood, and can preserve the quality of the vegetable or fruit or the seafood in a simple manner and effectively merely by bringing the vegetable or fruit or the seafood into contact with the quality-preserving agent.

IPC Classes  ?

  • A23B 7/10 - Preserving with acidsAcid fermentation
  • A23B 4/12 - Preserving with acidsAcid fermentation
  • A23B 7/153 - Preserving or ripening with chemicals not covered by group or in the form of liquids or solids

46.

MANGANESE-RICH YEAST EXTRACT, METHOD FOR PRODUCING SAME, AND USE OF MANGANESE-RICH YEAST EXTRACT

      
Application Number JP2013064619
Publication Number 2014/007000
Status In Force
Filing Date 2013-05-27
Publication Date 2014-01-09
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yukawa, Mai
  • Takahashi, Takayasu
  • Kodoi, Rie

Abstract

A method for producing a manganese-rich yeast extract, which involves an extraction step of suspending manganese-containing yeast in a solution containing a carboxylic acid and/or a carboxylic acid salt and then separating the resultant suspension into a solid component and a liquid component; a manganese-rich yeast extract; a food; a composition for a culture medium for an edible lactic acid bacterium; a culture medium for an edible lactic acid bacterium; and a method for culturing an edible lactic acid bacterium.

IPC Classes  ?

  • C12N 1/16 - YeastsCulture media therefor
  • A23L 1/28 - Edible extracts or preparations of fungi (for medicinal purposes A61K)
  • C12N 1/20 - BacteriaCulture media therefor

47.

QUALITY IMPROVING AGENT FOR BREADS, CONFECTIONERIES, DOUGHNUTS, PIES AND CHINESE DUMPLING SKINS

      
Application Number JP2013060373
Publication Number 2013/154030
Status In Force
Filing Date 2013-04-04
Publication Date 2013-10-17
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor Ishihara, Eisuke

Abstract

[Problem] To provide a highly safe preparation, method and the like whereby the qualities of at least one product selected from among breads, confectioneries, doughnuts, pies and Chinese dumpling skins can be easily and effectively improved. [Solution] A quality improving agent which comprises, as active ingredients, glycine and a pentose and/or a hexose. By kneading the quality improving agent into a dough, at least one quality improving effect can be exerted on at least one product selected from among breads, confectioneries, doughnuts, pies and Chinese dumpling skins, said quality improving effect being selected from, in particular: imparting a baked and/or fried brown color and promoting browning; shortening the baking and/or frying time; lowering the baking and/or frying temperature; reducing moisture loss in the baking and/or frying step and improving the texture; preventing skin-peeling and cracking in baked frozen breads or parbaked frozen products; and thinning the crust film of baked breads and thus improving the texture and increasing the crumb ratio.

IPC Classes  ?

48.

YEAST EXTRACT WITH HIGH COPPER CONTENT, METHOD FOR PRODUCING SAME, AND AGENT FOR MAINTAINING AND RESTORING GREEN COLOR OF FOODS AND VEGETABLES

      
Application Number JP2013057806
Publication Number 2013/146465
Status In Force
Filing Date 2013-03-19
Publication Date 2013-10-03
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Kodoi, Rie
  • Takahashi, Takayasu
  • Urasaki, Hiromi

Abstract

A method for producing a yeast extract with a high copper content, said method being characterized by compirising an extraction step for suspending a copper-containing yeast in a solution containing a carboxylic acid and/or a carboxylic acid salt and then separating the solid component of the obtained suspension from the liquid component; a yeast extract with a high copper content; and an agent for maintaining and restoring the green color of foods and vegetables.

IPC Classes  ?

  • A23L 1/28 - Edible extracts or preparations of fungi (for medicinal purposes A61K)
  • A23L 1/272 - Retaining or modifying natural colour by use of additives, e.g. optical brighteners (A23L 1/275 takes precedence);;

49.

QUALITY-KEEPING AGENT FOR PEELED AND/OR CUT VEGETABLES AND FRUITS, AND/OR FISH AND SHELLFISH

      
Application Number JP2013059681
Publication Number 2013/147227
Status In Force
Filing Date 2013-03-29
Publication Date 2013-10-03
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Urasaki, Hiromi
  • Matsumoto, Hisato

Abstract

[Problem] To provide a novel quality-keeping agent with a high safety whereby the qualities of peeled and/or cut vegetables, fruits and so on can be easily and effectively maintained during storage. [Solution] During cold or room-temperature storage of peeled and/or cut vegetables or fruits, color change, browning and so on can be prevented and the qualities can be easily and effectively maintained simply by using, as the active components, three components (i.e., sodium citrate, alum and α-lipoic acid) or four components (i.e., sodium citrate, alum, α-lipoic acid and sodium tartrate) and contacting the peeled and/or cut vegetables or fruits therewith.

IPC Classes  ?

  • A23L 3/3508 - Organic compounds containing oxygen containing carboxyl groups
  • A23B 7/10 - Preserving with acidsAcid fermentation
  • A23L 1/325 - Food-from-the-sea products; Fish products; Fish meal; Fish-egg substitutes

50.

LIQUID FERMENTED MILK AND METHOD FOR PRODUCING SAME

      
Application Number JP2012078793
Publication Number 2013/073424
Status In Force
Filing Date 2012-11-07
Publication Date 2013-05-23
Owner
  • MEIJI CO., LTD. (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Goto, Yuko
  • Tanaka, Iyo
  • Yamada, Shigeru
  • Kitajima, Masahiro

Abstract

Provided is a method for producing a liquid fermented milk having favorable flavor and appearance, having no occurrence of solid content floating up, having no contained large particles observed with the naked eye after completion of stirring fermentation, and having a rich aroma and the like deriving from fermentation by yeast. The method for producing a liquid fermented milk contains: (A) a static fermentation step that, after adding a lactobacillus to the starting material for fermented milk, causes static fermentation to obtain a lactic acid fermentation product; (B) a stirring fermentation step that, after adding yeast to the lactic acid fermentation product obtained in step (A), causes stirring fermentation to obtain a liquid fermented milk; and (C) a homogenization step for subjecting the liquid fermented milk obtained in step (B) to homogenization processing.

IPC Classes  ?

  • A23C 9/127 - Fermented milk preparationsTreatment using microorganisms or enzymes using microorganisms of the genus lactobacteriaceae and other microorganisms or enzymes, e.g. kefir, koumiss
  • A23C 9/13 - Fermented milk preparationsTreatment using microorganisms or enzymes using additives

51.

METHOD FOR PRODUCING ZINC-RICH YEAST EXTRACT, ZINC-RICH YEAST EXTRACT, AND GREEN-RETAINING/-RESTORING AGENT FOR FOOD AND VEGETABLES

      
Document Number 02850911
Status In Force
Filing Date 2012-09-27
Open to Public Date 2013-04-11
Grant Date 2017-04-18
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Kodoi, Rie
  • Takahashi, Takayasu
  • Oka, Osamu
  • Urasaki, Hiromi

Abstract

A method for producing a high-zinc-content yeast extract, including extracting the high-zinc-content yeast extract by suspending zinc-containing yeast into a solution containing a carboxylic acid, a carboxylic acid salt, or both thereof to thereby obtain a suspension liquid, and separating a solid component and a liquid component of the suspension liquid; the high-zinc-content yeast extract; food; and an agent for maintaining and restoring a green color of vegetables.

IPC Classes  ?

52.

METHOD FOR PRODUCING ZINC-RICH YEAST EXTRACT, ZINC-RICH YEAST EXTRACT, AND GREEN-RETAINING/-RESTORING AGENT FOR FOOD AND VEGETABLES

      
Application Number JP2012074930
Publication Number 2013/051461
Status In Force
Filing Date 2012-09-27
Publication Date 2013-04-11
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Kodoi, Rie
  • Takahashi, Takayasu
  • Oka, Osamu
  • Urasaki, Hiromi

Abstract

A method for producing a zinc-rich yeast extract, the method comprising an extraction step for suspending a yeast containing zinc in a solution including carboxylic acid and/or carboxylic acid salt, and separating the solid component and liquid component of the resulting suspension; a zinc-rich yeast extract; and a green-retaining/-restoring agent for food and vegetables.

IPC Classes  ?

  • A23L 1/28 - Edible extracts or preparations of fungi (for medicinal purposes A61K)
  • A23L 1/212 - Preparation of fruits or vegetables (of pulse A23L 1/20; treating harvested fruit or vegetables in bulk A23N)
  • A23L 1/272 - Retaining or modifying natural colour by use of additives, e.g. optical brighteners (A23L 1/275 takes precedence);;

53.

METHOD FOR CULTURING MAMMALIAN CELL IN SYSTEM CONTAINING LAMININ 511

      
Application Number JP2012075111
Publication Number 2013/047763
Status In Force
Filing Date 2012-09-28
Publication Date 2013-04-04
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yamada, Munehiro
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

The purpose of the present invention is to provide a method for culturing a mammalian cell in a system containing laminin 511. The method according to the present invention is characterized by culturing the cell under such conditions that a blood protein other than an extracellular matrix protein, which is serum, serum albumin, prealbumin, an immunoglobulin, α-globulin, β-globulin, α1-antitrypsin (α1-AT), haptoglobin (Hp), α2-macroglobulin (α2-M), α-fetoprotein (AFP), transferrin, a retinol-binding protein (RBP) or adiponectin, a polypeptide and/or a peptide selected from the group consisting of gelatin, a protein belonging to a tumor necrosis factor (TNF) family and peptone, and laminin 511 are solid-phased.

IPC Classes  ?

  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues
  • C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • C12N 5/0786 - MonocytesMacrophages
  • C12N 5/0789 - Stem cellsMultipotent progenitor cells
  • C12N 5/09 - Tumour cells

54.

FROZEN WHIPPING CREAM, METHOD FOR PRODUCING SAME, WHIPPED CREAM AND METHOD FOR PRODUCING SAME

      
Application Number JP2011071341
Publication Number 2013/042186
Status In Force
Filing Date 2011-09-20
Publication Date 2013-03-28
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Wakana, Satoru
  • Hasegawa, Kiyoshi
  • Takahashi, Takayasu

Abstract

The objective of the present invention is to provide: a method for producing frozen whipping cream wherein the cream can be refrigerated, the creaminess of the cream after thawing is the same as refrigerated cream, and quality in terms of smoothness and melting in the mouth when made into whipped cream is the same as whipped cream made by whipping refrigerated cream; frozen whipping cream produced by the method; and whipped cream using the frozen whipping cream and a method for making the same. The present invention is: a method for producing frozen whipping cream which includes a cooling step for cooling fresh cream, the fresh cream being passed from 0°C to -5°C in 8 minutes or less in the cooling step; frozen whipping cream produced by the method; whipped cream using the frozen whipping cream; and a method for making the same.

IPC Classes  ?

55.

Frozen fresh cream to be whipped, method for producing the frozen fresh cream, whipped cream, and method for producing the whipped cream

      
Application Number 13555619
Grant Number 09339046
Status In Force
Filing Date 2012-07-23
First Publication Date 2013-03-21
Grant Date 2016-05-17
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Wakana, Satoru
  • Hasegawa, Kiyoshi
  • Takahashi, Takayasu

Abstract

A method for producing frozen fresh cream to be whipped, the method including: cooling fresh cream, wherein in the cooling, the fresh cream is cooled to a temperature of −5° C. or lower and is changed from 0° C. to −5° C. for 8 minutes or shorter.

IPC Classes  ?

56.

POTENTIATOR OF CANCER IMMUNITY CONTAINING RANKL ANTAGONIST

      
Application Number JP2012059130
Publication Number 2012/133914
Status In Force
Filing Date 2012-03-28
Publication Date 2012-10-04
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Akiyama, Taishin
  • Yanai, Hiromi
  • Akiyama, Nobuko
  • Yasuda, Hisataka

Abstract

The invention provides a potentiator of cancer immunity containing a compound which blocks the action of RANKL. The invention is a potentiator of cancer immunity containing, as an active ingredient, a RANKL antagonist such as an anti-RANKL neutralizing antibody.

IPC Classes  ?

  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
  • A61P 35/00 - Antineoplastic agents
  • A61P 37/04 - Immunostimulants

57.

CANCER IMMUNOPOTENTIATING AGENT CONTAINING RANKL ANTAGONIST

      
Document Number 02831247
Status In Force
Filing Date 2012-03-28
Open to Public Date 2012-10-04
Grant Date 2020-07-21
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Akiyama, Taishin
  • Yanai, Hiromi
  • Akiyama, Nobuko
  • Yasuda, Hisataka

Abstract

The invention provides a potentiator of cancer immunity containing a compound which blocks the action of RANKL. The invention is a potentiator of cancer immunity containing, as an active ingredient, a RANKL antagonist such as an anti-RANKL neutralizing antibody.

IPC Classes  ?

  • A61K 39/395 - AntibodiesImmunoglobulinsImmune serum, e.g. antilymphocytic serum
  • A61P 35/00 - Antineoplastic agents

58.

METHOD FOR IMPROVING THE QUALITY OF BREAD, ETC.

      
Application Number JP2011060999
Publication Number 2011/142439
Status In Force
Filing Date 2011-05-12
Publication Date 2011-11-17
Owner Oriental Yeast Co., Ltd. (Japan)
Inventor
  • Ishihara, Eisuke
  • Matsumoto, Hisato
  • Sasaki, Yuichi
  • Sato, Nobuyoshi

Abstract

Disclosed is a method which improves the quality of at least one item chosen from bread, noodles and sweets, and which imparts a softness and moistness and makes the item not prone to aging even after a certain period has elapsed after manufacture (aging is suppressed and prevented); also disclosed is an agent used in said method. Softness and moistness can be imparted to at least one item chosen from bread, noodles and sweets, and aging can be suppressed and prevented during storage after manufacture by adding to wheat flour and/or rice flour, which is the main ingredient, four components: α-amylase, β-amylase and a partial α-starch, and a processed product of seaweed belonging to the genus Lessonia of the order Laminariales.

IPC Classes  ?

  • A21D 2/36 - Vegetable material
  • A21D 2/18 - Carbohydrates
  • A21D 2/26 - Proteins
  • A21D 13/00 - Finished or partly finished bakery products
  • A23G 3/00 - SweetmeatsConfectioneryMarzipanCoated or filled products
  • A23G 3/34 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof
  • A23L 1/16 - Types of pasta, e.g. macaroni, noodles

59.

METHOD FOR CULTURING CELLS IN SYSTEM CONTAINING LAMININ-5

      
Application Number JP2011058265
Publication Number 2011/125860
Status In Force
Filing Date 2011-03-31
Publication Date 2011-10-13
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yasuda, Hisataka
  • Yamada, Munehiro
  • Taketani, Yukiko
  • Tomimori, Yoshiya
  • Mori, Kaoru

Abstract

Disclosed is a method for culturing cells in a system containing laminin-5. This method is characterized by including a culture system for polypeptides selected from a group consisting of serum, serum albumin, prealbumin, immunoglobulin, alpha globulins, beta globulins, α1-antitrypsin (α1-AT), haptoglobin (Hp), α2-macroglobulin (α2M), α-fetoprotein (AFP), transferrin, retinol binding protein (RBP), and proteins in the blood other than extracellular matrix proteins as well as gelatin, proteins belonging to the tumor necrosis factor (TNF) family and peptones.

IPC Classes  ?

  • C12N 5/07 - Animal cells or tissues
  • C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • C12N 5/0786 - MonocytesMacrophages
  • C12N 5/0789 - Stem cellsMultipotent progenitor cells
  • C12N 5/0797 - Stem cellsProgenitor cells
  • C07K 14/525 - Tumour necrosis factor [TNF]
  • C07K 14/765 - Serum albumin, e.g. HSA
  • C07K 14/78 - Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
  • C07K 14/79 - Transferrins, e.g. lactoferrins, ovotransferrins

60.

Fusion protein composed of matrix metalloproteinase-2 inhibitor peptide derived from amyloid-B precursor protein and tissue inhibitor of metalloproteinase-2

      
Application Number 13123210
Grant Number 08802627
Status In Force
Filing Date 2009-10-05
First Publication Date 2011-08-11
Grant Date 2014-08-12
Owner Oriental Yeast Co., Ltd. (Japan)
Inventor Higashi, Shouichi

Abstract

The present invention provides an agent capable of inhibiting MMP-2 specifically. Disclosed is a fusion molecule composed of a β-amyloid precursor protein molecule-derived domain having an activity of selectively inhibiting matrix metalloproteinase-2 and a tissue inhibitor of metalloproteinase capable of binding to latent matrix metalloproteinase. Also disclosed are a pharmaceutical composition, a cancer metastasis and/or angiogenesis inhibitor, a therapeutic and/or prophylactic for cardiovascular diseases, and a matrix metalloproteinase-2 inhibitor, each of which comprises the fusion molecule.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • C12P 21/04 - Cyclic or bridged peptides or polypeptides, e.g. bacitracin
  • C07K 14/81 - Protease inhibitors
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals

61.

Inducer of chondrocyte proliferation and differentiation

      
Application Number 12998253
Grant Number 09435811
Status In Force
Filing Date 2009-09-09
First Publication Date 2011-07-21
Grant Date 2016-09-06
Owner ORIENTAL YEAST CO., LTD (Japan)
Inventor
  • Yasuda, Hisataka
  • Furuya, Yuriko

Abstract

This invention provides a method for administration of an effective amount of RANKL-binding molecules that act on prechondrocytes and/or mesenchymal stem cells, accelerate cartilage differentiation, proliferation, and maturation of such cells, enhance chondrocyte differentiation, and induce chondrocyte proliferation to induce chondrocyte proliferation and differentiation or increase cartilage matrix production and a pharmaceutical composition used for inducing chondrocyte proliferation and differentiation or increasing cartilage matrix production. The pharmaceutical composition used for treatment or prevention of a chondropathies comprises, as an active ingredient, a compound that acts on prechondrocytes and/or mesenchymal stem cells and induces at least one of the following: (a) acceleration of prechondrocyte and/or mesenchymal stem cell differentiation; (b) acceleration of prechondrocyte and/or mesenchymal stem cell proliferation; (c) acceleration of prechondrocyte and/or mesenchymal stem cell maturation; (d) enhancement of chondrocyte differentiation; (e) chondrocyte proliferation; and (f) increased production of the cartilage matrix.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides
  • A61K 39/00 - Medicinal preparations containing antigens or antibodies
  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
  • G01N 33/68 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing involving proteins, peptides or amino acids
  • A61K 38/18 - Growth factorsGrowth regulators
  • A61K 38/19 - CytokinesLymphokinesInterferons
  • A61K 38/08 - Peptides having 5 to 11 amino acids
  • C12N 5/07 - Animal cells or tissues

62.

Yeast having immunopotentiating capability and food or feed

      
Application Number 12797014
Grant Number 09127322
Status In Force
Filing Date 2010-06-09
First Publication Date 2010-12-09
Grant Date 2015-09-08
Owner
  • ORIENTAL YEAST CO., LTD. (Japan)
  • Masayuki Azuma (Japan)
Inventor
  • Azuma, Masayuki
  • Tachibana, Taro
  • Furukawa, Shuhei
  • Nakajima, Ryoichi
  • Watanabe, Hajime
  • Kobayashi, Sayumi

Abstract

660 of the YPD liquid medium to 1.0 or more.

IPC Classes  ?

  • C12N 1/18 - Baker's yeastBrewer's yeast
  • C12R 1/865 - Saccharomyces cerevisiae
  • A21D 8/04 - Methods for preparing doughTreating dough prior to baking treating dough with microorganisms or enzymes
  • A23K 1/00 - Animal feeding-stuffs
  • A23K 1/18 - specially adapted for particular animals

63.

Model animal in which state of disease condition is observable in real time, gene construct for achieving the same and use of the same

      
Application Number 11908202
Grant Number 08487087
Status In Force
Filing Date 2006-03-10
First Publication Date 2010-10-28
Grant Date 2013-07-16
Owner Oriental Yeast Co., Ltd. (Japan)
Inventor
  • Kondoh, Shinae
  • Harada, Hiroshi
  • Hiraoka, Masahiro
  • Yamada, Shu-Ichi

Abstract

Provided is a technique for observing in real time the state of a disease condition in a tissue of an animal or the state of a functionally adverse condition which is a prelude to the disease condition without injuring the animal. This can be achieved by the use of a gene construct having a reporter gene integrated under the control of a hypoxia responsible promoter an ODD domain (oxygen dependent degradation domain) integrated upstream to the reporter gene.

IPC Classes  ?

  • C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

64.

ORIENTAL YEAST CO., LTD.

      
Application Number 149413000
Status Registered
Filing Date 2010-08-31
Registration Date 2016-09-01
Owner Oriental Yeast Co., Ltd. (Japan)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

(1) Chemical additives for use in the manufacture of food; KANSUI, namely, food additive for making Chinese noodle; biochemical reagents, namely, diagnostic reagents for clinical laboratory use; enzymes for food manufacturing; enzymes for the bakery industry as ingredients used in the manufacture of biochemistry reagents.

65.

Miscellaneous Design

      
Application Number 009343203
Status Registered
Filing Date 2010-08-31
Registration Date 2011-02-25
Owner ORIENTAL YEAST CO., LTD. (Japan)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 29 - Meat, dairy products, prepared or preserved foods
  • 30 - Basic staples, tea, coffee, baked goods and confectionery

Goods & Services

Quality improving agents for confectionery and bakery; dough conditioners; dough stabilizers; kansui (food additive for manufacture of Chinese noodle); ingredients for use in the manufacture of foods; preservatives for foodstuffs; bacteriostatic agents for foodstuffs; diagnostic reagents and preparations, except for medical or veterinary use; reagents for scientific purposes; immunochemistry reagents; biochemistry reagents; enzymes [other than for medical or veterinary use]; culture media for microbiology; flavour enhancers for foodstuffs; chemical products for the preparation of flavourings; softening preparations for pounded rice cakes (mochi) (chemical preparations). Dietary food supplements; powdered and granulated processed dietary food supplements made of yeast; biological and chemical preparations and reagents for medical or veterinary use; enzymes for medical or veterinary use. Buttercream; curry [prepared meals with or without rice]; prepared sweet or fruit fillings. Yeast; yeast extracts; confectionery made mainly of wheat flour and starches; confectionery and bakery creams (paste) made mainly from wheat flour and starches; custard powder; curry powder; curry paste; curry sauces; bakery products; mixes for making bakery products; pre-ferment; baking powder; mayonnaise; powdered mayonnaise; dressings for food; rice; brown rice (prepared); sprouted rice; roasted rye; flavourings and essences for food and beverages; fermented liquid flavouring; dough; dough mix; softening preparations for pounded rice cakes (mochi) (other than chemical preparations).

66.

ORIENTAL YEAST CO., LTD.

      
Serial Number 85976163
Status Registered
Filing Date 2010-08-31
Registration Date 2012-02-28
Owner Oriental Yeast Co., Ltd. (Japan)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

Chemicals for industrial purposes; chemical additives for use in the manufacture of food; Kansui, namely, chemical additives for use in the manufacture of food; [ bacteriostatic agents for use in the manufacture of food; ] Biochemical reagents used for non-medical purposes; [ Enzymes for use in the food industry; ]enzymes as ingredients used in manufacture of biochemistry reagents; [ Bacteria for use in food manufacture ]

67.

ORIENTAL KOBO KOGYO KABUSHIKI KAISHA

      
Application Number 149413100
Status Registered
Filing Date 2010-08-31
Registration Date 2016-09-01
Owner Oriental Yeast Co., Ltd. (Japan)
NICE Classes  ? 01 - Chemical and biological materials for industrial, scientific and agricultural use

Goods & Services

(1) Chemical additives for use in the manufacture of food; KANSUI, namely, food additive for making Chinese noodle; biochemical reagents, namely, diagnostic reagents for clinical laboratory use; enzymes for food manufacturing; enzymes for the bakery industry as ingredients used in the manufacture of biochemistry reagents.

68.

ORIENTAL YEAST CO., LTD.

      
Application Number 009343039
Status Registered
Filing Date 2010-08-31
Registration Date 2011-02-25
Owner ORIENTAL YEAST CO., LTD. (Japan)
NICE Classes  ?
  • 01 - Chemical and biological materials for industrial, scientific and agricultural use
  • 05 - Pharmaceutical, veterinary and sanitary products
  • 29 - Meat, dairy products, prepared or preserved foods
  • 30 - Basic staples, tea, coffee, baked goods and confectionery

Goods & Services

Quality improving agents for confectionery and bakery; dough conditioners; dough stabilizers; kansui (food additive for manufacture of Chinese noodle); ingredients for use in the manufacture of foods; preservatives for foodstuffs; bacteriostatic agents for foodstuffs; diagnostic reagents and preparations, except for medical or veterinary use; reagents for scientific purposes; immunochemistry reagents; biochemistry reagents; enzymes [other than for medical or veterinary use]; culture media for microbiology; flavour enhancers for foodstuffs; chemical products for the preparation of flavourings; softening preparations for pounded rice cakes (mochi) (chemical preparations). Dietary food supplements; powdered and granulated processed dietary food supplements made of yeast; biological and chemical preparations and reagents for medical or veterinary use; enzymes for medical or veterinary use. Buttercream; curry [prepared meals with or without rice]; prepared sweet or fruit fillings. Yeast; yeast extracts; confectionery made mainly of wheat flour and starches; confectionery and bakery creams (paste) made mainly from wheat flour and starches; custard powder; curry powder; curry paste; curry sauces; bakery products; mixes for making bakery products; pre-ferment; baking powder; mayonnaise; powdered mayonnaise; dressings for food; rice; brown rice (prepared); sprouted rice; roasted rye; flavourings and essences for food and beverages; fermented liquid flavouring; dough; dough mix; softening preparations for pounded rice cakes (mochi) (other than chemical preparations).

69.

Method of separating and distinguishing walnut from pecan nut

      
Application Number 12524735
Grant Number 08329406
Status In Force
Filing Date 2008-01-30
First Publication Date 2010-08-19
Grant Date 2012-12-11
Owner
  • Oriental Yeast Co., Ltd. (Japan)
  • Nissin Foods Holdings Co., Ltd. (Japan)
Inventor
  • Yano, Takeo
  • Sakai, Yumiko
  • Uchida, Kouji
  • Nakao, Yoshiki
  • Ishihata, Kimie
  • Nakano, Shigeru
  • Yamada, Toshihiro

Abstract

Provided is a method whereby walnut can be simply, rapidly and accurately separated and distinguished from pecan nut. The method involves a PCR method for specifically detecting nuts of the family Juglandaceae and identifying the matK sequence of pecan nut to thereby discriminate walnut and pecan nut from each other optionally using restriction enzymes.

IPC Classes  ?

  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
  • C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical

70.

Polypeptide for unstabilizing protein in cells under aerobic conditions and DNA encoding the same

      
Application Number 10479700
Grant Number 07700754
Status In Force
Filing Date 2003-12-05
First Publication Date 2010-04-20
Grant Date 2010-04-20
Owner
  • NANO FACTORY CO., LTD. (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Hiraoka, Masahiro
  • Kondoh, Shinae
  • Harada, Hiroshi

Abstract

To identify a domain in HIF-1α protein, which participates in stabilization of a fused protein, DNA encoding the following polypeptide (A) or (B) is provided: (A) a polypeptide having the amino acid sequence of SEQ ID NO: 1 (B) a polypeptide having an amino acid sequence comprising at least 16 amino acid residues in the amino acid sequence of SEQ ID NO: 1, and imparting stability dependent on an oxygen concentration to other protein in a cell harboring a fused protein, when the polypeptide is fused with a nuclear localization signal and the other protein to form the fused protein.

IPC Classes  ?

  • C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
  • C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
  • C07K 14/00 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof

71.

FUSION PROTEIN COMPOSED OF MATRIX METALLOPROTEINASE-2 INHIBITOR PEPTIDE DERIVED FROM AMYLOID-Β PRECURSOR PROTEIN AND TISSUE INHIBITOR OF METALLOPROTEINASE-2

      
Application Number JP2009067320
Publication Number 2010/041617
Status In Force
Filing Date 2009-10-05
Publication Date 2010-04-15
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor Higashi, Shouichi

Abstract

Disclosed is a substance capable of inhibiting MMP-2 specifically.  Specifically disclosed is a fusion molecule composed of: a region which has an activity to selectively inhibit matrix metalloproteinase-2 and is contained in an amyloid-β precursor protein molecule; and a tissue inhibitor of metalloproteinase which can bind to a latent matrix metalloproteinase.  Also disclosed are a pharmaceutical composition, a cancer metastasis and/or angiogenesis inhibitor, a therapeutic and/or prophylactic agent for cardiovascular diseases, and a matrix metalloproteinase-2 inhibitor, each of which comprises the fusion molecule.

IPC Classes  ?

  • C12N 15/09 - Recombinant DNA-technology
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 9/00 - Drugs for disorders of the cardiovascular system
  • A61P 9/04 - Inotropic agents, i.e. stimulants of cardiac contractionDrugs for heart failure
  • A61P 9/10 - Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
  • A61P 35/04 - Antineoplastic agents specific for metastasis
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
  • C07K 14/81 - Protease inhibitors
  • C07K 19/00 - Hybrid peptides
  • C12N 1/15 - Fungi Culture media therefor modified by introduction of foreign genetic material
  • C12N 1/19 - YeastsCulture media therefor modified by introduction of foreign genetic material
  • C12N 1/21 - BacteriaCulture media therefor modified by introduction of foreign genetic material
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12N 9/99 - Enzyme inactivation by chemical treatment

72.

Osteopenia animal model

      
Application Number 12445050
Grant Number 08334261
Status In Force
Filing Date 2007-10-11
First Publication Date 2010-04-08
Grant Date 2012-12-18
Owner Oriental Yeast Co., Ltd. (Japan)
Inventor
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

The present invention provides a method for producing an osteopenia animal model by RANKL administration and an osteopenia animal model. Also, a method for producing an osteopenia animal model, comprising administering soluble RANKL or a fused protein of soluble RANKL with an epitope tag to a non-human animal so as to promote vivo osteoclast differentiation and activation in the non-human animal, and an osteopenia animal model produced by the method are provided.

IPC Classes  ?

  • A61K 38/00 - Medicinal preparations containing peptides

73.

NOVEL CARTILAGE CELL PROLIFERATION AND DIFFERENTIATION INDUCER

      
Application Number JP2009066060
Publication Number 2010/038610
Status In Force
Filing Date 2009-09-09
Publication Date 2010-04-08
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yasuda, Hisataka
  • Furuya, Yuriko

Abstract

Disclosed is a method for inducing the proliferation/differentiation of a cartilage cell or increasing the production of a cartilage substrate by administering an effective amount of a RANKL-binding molecule which can act on a cartilage progenitor cell and/or a mesenchymal stem cell to promote the differentiation of the cartilage progenitor cell and/or the mesenchymal stem cell into a cartilage or the proliferation or maturation of the cartilage progenitor cell and/or the mesenchymal stem cell, enhance the differentiation of a cartilage cell and induce the proliferation of a cartilage cell. Also disclosed is a pharmaceutical composition for inducing the proliferation/differentiation of a cartilage cell or increasing the production of a cartilage substrate. Specifically disclosed is a pharmaceutical composition for treating or preventing a cartilage disease, which comprising a compound capable of acting on a cartilage progenitor cell and/or a mesenchymal stem cell to induce at least one phenomenon selected from the following items (a) to (f) as an active ingredient: (a) the promotion of the differentiation of the cartilage progenitor cell and/or the mesenchymal stem cell; (b) the promotion of the proliferation of the cartilage progenitor cell and/or the mesenchymal stem cell; (c) the promotion of the maturation of the cartilage progenitor cell and/or the mesenchymal stem cell; (d) the enhancement of the cartilage cell differentiation; (e) the proliferation of a cartilage cell; and (f) the increase in the production of a cartilage substrate.

IPC Classes  ?

  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
  • A61P 29/00 - Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agentsNon-steroidal antiinflammatory drugs [NSAID]
  • A61P 43/00 - Drugs for specific purposes, not provided for in groups
  • G01N 33/15 - Medicinal preparations
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

74.

STANDARD MOLECULE FOR USE IN REAL-TIME PCR TEST, AND DETECTION OF THE STANDARD MOLECULE

      
Application Number JP2009061459
Publication Number 2009/157465
Status In Force
Filing Date 2009-06-24
Publication Date 2009-12-30
Owner Oriental  Yeast  Co.,  Ltd. (Japan)
Inventor
  • Yano,  takeo
  • Sakai,  yumiko
  • Kurihara,  takashi

Abstract

Disclosed are: a standard molecule characterized in that the presence of a false-positive result caused by unintended contamination of a reagent, a sample or the like with the standard molecule can be confirmed simultaneously with the determination of the test results in real-time PCR test; a primer; a probe; and a test method using the standard molecule, the primer and the probe. In a real-time PCR test, the presence of a false-positive result caused by contamination with a standard molecule for a real-time PCR test can be determined simultaneously by carrying out the test using the standard molecule and a primer/probe, wherein the standard molecule contains both an artificial DNA sequence and a target region of DNA to be tested, wherein the artificial DNA sequence can be amplified under the same PCR conditions and in the same reaction vessel as those for the target region of the DNA to be tested in the real-time PCR test, and wherein the primer/probe is one used for amplifying/detecting only the DNA sequence.

IPC Classes  ?

  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
  • C12N 15/09 - Recombinant DNA-technology

75.

HEAT-STABILIZATION OF FOOD ANTIOXIDANT

      
Application Number JP2009060502
Publication Number 2009/151042
Status In Force
Filing Date 2009-06-09
Publication Date 2009-12-17
Owner Oriental  Yeast  Co.,  Ltd. (Japan)
Inventor
  • Yamamoto,  hideki
  • Takahashi,  takayasu
  • Fukushima,  saori

Abstract

To newly develop a system for imparting heat resistance to a food antioxidant (in particular, a food antioxidant containing β-amylase as the active ingredient). To solve the above-described problem, a material for imparting heat resistance to a food antioxidant containing β-amylase as the active ingredient that is characterized by being at least one member selected from among a yeast-treated material, a yam powder and a modified cellulose and capable of imparting heat resistance of 90°C or higher has been developed.

IPC Classes  ?

  • A23L 3/3463 - Organic compounds; Microorganisms; Enzymes
  • A21D 13/00 - Finished or partly finished bakery products
  • A21D 13/08 - Pastry, e.g. cake, biscuit, puff-pastry (icing or frosting or mixes therefor A23G 3/00)
  • A23G 3/34 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof
  • A23G 3/48 - Sweetmeats, confectionery or marzipanProcesses for the preparation thereof characterised by the composition containing plants or parts thereof, e.g. fruits, seeds, extracts
  • A23L 1/10 - containing cereal-derived products
  • A23L 1/48 - Food compositions or treatment thereof not covered by the preceding subgroups
  • C12N 9/96 - Stabilising an enzyme by forming an adduct or a compositionForming enzyme conjugates

76.

POLYNUCLEOTIDE FOR RELEASING RECOMBINANT PROTEIN TO THE OUTSIDE OF EUKARYOTIC CELL

      
Application Number JP2009060811
Publication Number 2009/148194
Status In Force
Filing Date 2009-06-08
Publication Date 2009-12-10
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Saito, Saburo
  • Akiyama, Nobutake
  • Ohno, Yuji

Abstract

Disclosed is a method for producing a recombinant protein efficiently by expressing the recombinant protein in a eukaryotic cell host and releasing the recombinant protein to the outside of the cell. Specifically disclosed is a polynucleotide which can be used for producing a recombinant protein in a host cell.  The polynucleotide comprises: a polynucleotide encoding an endoplasmic reticulum-insertion signal sequence and a glycosylated sequence comprising a sequence represented by the formula: Asn-X-(Thr/Ser) [wherein X represents an amino acid residue other than proline]; and a polynucleotide encoding a protein of interest that cannot be released efficiently to the outside of a host even when the protein is fused with an endoplasmic reticulum-insertion signal sequence.  The polynucleotide enables the release of the protein of interest to the outside of the hose cell in a glycosylation-dependent manner.

IPC Classes  ?

  • C12N 15/09 - Recombinant DNA-technology
  • C07K 19/00 - Hybrid peptides
  • C12N 1/15 - Fungi Culture media therefor modified by introduction of foreign genetic material
  • C12N 1/19 - YeastsCulture media therefor modified by introduction of foreign genetic material
  • C12N 5/10 - Cells modified by introduction of foreign genetic material, e.g. virus-transformed cells
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

77.

Technique for culture of mesenchymal stem cell utilizing laminin-5

      
Application Number 12064626
Grant Number 08728814
Status In Force
Filing Date 2006-08-17
First Publication Date 2009-10-29
Grant Date 2014-05-20
Owner Oriental Yeast Co., Ltd. (Japan)
Inventor
  • Miyazaki, Kaoru
  • Hashimoto, Junko
  • Kariya, Yoshinobu

Abstract

Disclosed is an agent for improving at least one activity selected from the group consisting of the growth activity, adhesion activity and extension activity of mesenchymal stem cells, which comprises laminin-5 as an active ingredient. A method of culturing mesenchymal stem cells; a method of isolating mesenchymal stem cells; and a medium, vessel or sheet for use in culturing mesenchymal stem cells are also provided.

IPC Classes  ?

  • C12N 5/00 - Undifferentiated human, animal or plant cells, e.g. cell linesTissuesCultivation or maintenance thereofCulture media therefor
  • C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
  • C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

78.

METHOD FOR PROLIFERATION OF PLURIPOTENT STEM CELL

      
Application Number JP2009057041
Publication Number 2009/123349
Status In Force
Filing Date 2009-03-31
Publication Date 2009-10-08
Owner
  • ORIENTAL YEAST CO., LTD. (Japan)
  • KYOTO UNIVERSITY (Japan)
Inventor
  • Yasuda, Hisataka
  • Yamada, Munehiro
  • Miyazaki, Kaoru
  • Takahashi, Kazutoshi

Abstract

The object aims to proliferate a pluripotent stem cell efficiently in a system which does not use any animal-derived material such as a feeder cell or a serum. Thus, disclosed is a method for proliferating a pluripotent stem cell, which comprises culturing the pluripotent stem cell in a culture medium containing no feeder cell or serum in a system containing laminin-5.

IPC Classes  ?

  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
  • C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
  • C12N 15/12 - Genes encoding animal proteins

79.

METHOD FOR PROLIFERATION OF PLURIPOTENT STEM CELLS

      
Document Number 02718830
Status In Force
Filing Date 2009-03-31
Open to Public Date 2009-10-08
Grant Date 2017-04-18
Owner
  • KYOTO UNIVERSITY (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yasuda, Hisataka
  • Yamada, Munehiro
  • Miyazaki, Kaoru
  • Takahashi, Kazutoshi

Abstract

The object aims to proliferate a pluripotent stem cell efficiently in a system which does not use any animal-derived material such as a feeder cell or a serum. Thus, disclosed is a method for proliferating a pluripotent stem cell, which comprises culturing the pluripotent stem cell in a culture medium containing no feeder cell or serum in a system containing laminin-5.

IPC Classes  ?

  • C12N 5/0735 - Embryonic stem cellsEmbryonic germ cells
  • C12N 5/071 - Vertebrate cells or tissues, e.g. human cells or tissues

80.

Detection of inflammatory disease and composition for prevention or treatment of inflammatory disease

      
Application Number 12227244
Grant Number 08257933
Status In Force
Filing Date 2006-05-12
First Publication Date 2009-08-13
Grant Date 2012-09-04
Owner
  • Keio University (Japan)
  • Oriental Yeast Co., Ltd. (Japan)
Inventor
  • Maruyama, Kenta
  • Matsuo, Koichi
  • Yasuda, Hisataka

Abstract

A novel method for detection of an inflammatory disease and a novel composition for prevention or treatment of an inflammatory disease are provided. The method for detection of an inflammatory disease comprises using RANKL and/or OPG as a marker in a biological sample. The composition for prevention or treatment of an inflammatory disease comprises RANKL and/or M-CSF as an active ingredient.

IPC Classes  ?

  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
  • G01N 33/49 - Physical analysis of biological material of liquid biological material blood
  • C07K 14/51 - Bone morphogenic factorOsteogeninOsteogenic factorBone-inducing factor
  • C07K 14/705 - ReceptorsCell surface antigensCell surface determinants

81.

YEAST HAVING IMMUNOPOTENTIATING EFFECT AND FOOD OR FEED

      
Application Number JP2008072404
Publication Number 2009/075290
Status In Force
Filing Date 2008-12-10
Publication Date 2009-06-18
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Azuma, Masayuki
  • Tachibana, Taro
  • Furukawa, Shuhei
  • Nakajima, Ryoichi
  • Watanabe, Hajime
  • Kobayashi, Sayumi

Abstract

This object aims to provide a yeast which has a high safety, can exerts a high immunopotentiating effect even in the case of being taken as cells, is easily available and less expensive, can be directly employed in producing foods and can be cultured even at a low osmotic pressure, and a food containing this yeast. A yeast characterized by containing only a small amount of mannan in the cell wall, having an immunopotentiating effect and being capable of growing in YPD liquid medium having an osmotic pressure of 300 m Osm. The above-described yeast is preferably either of Saccharomyces cerevisiae FERM AP-21354 or Saccharomyces cerevisiae FERM AP-21355.

IPC Classes  ?

  • C12N 1/16 - YeastsCulture media therefor
  • A23K 1/16 - supplemented with accessory food factors; Salt blocks

82.

NOVEL BONE MASS INCREASING AGENT

      
Application Number JP2008060731
Publication Number 2008/150025
Status In Force
Filing Date 2008-06-05
Publication Date 2008-12-11
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Yasuda, Hisataka
  • Furuya, Yuriko
  • Taguchi, Yusuke

Abstract

Disclosed is a bone formation enhancing agent comprising an RANKL-acting molecule which can enhance the differentiation, maturation or calcification of an osteoblast or a cell capable of being differentiated into an osteoblast. Specifically disclosed is a pharmaceutical composition for the treatment or prevention of a metabolic bone disease accompanied by the decrease in bone mass, which comprises, as an active ingredient, a compound which can act on an RANKL located on an osteoblast or a cell capable of being differentiated into an osteoblast to accelerate the differentiation, proliferation, maturation or calcification of the osteoblast or the cell capable of being differentiated into an osteoblast.

IPC Classes  ?

  • A61K 45/00 - Medicinal preparations containing active ingredients not provided for in groups
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
  • A61P 19/08 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
  • A61P 19/10 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
  • C07K 14/705 - ReceptorsCell surface antigensCell surface determinants
  • C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
  • G01N 33/15 - Medicinal preparations
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

83.

DETERMINATION METHOD FOR ALLERGIC DISEASE

      
Application Number JP2008000242
Publication Number 2008/111281
Status In Force
Filing Date 2008-02-15
Publication Date 2008-09-18
Owner
  • THE UNIVERSITY OF TOKUSHIMA (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Kido, Hiroshi
  • Suzuki, Koichi

Abstract

It is intended to provide a determination method for an allergic disease which is capable of performing a multidimensional and comprehensive analysis with a small amount of a specimen and particularly suppressing a non-specific reaction as much as possible thereby to enable an accurate measurement with high sensitivity even if a body fluid other than blood such as saliva, nasal discharge or lacrimal fluid is used as the specimen. After a chemically-modified diamond/DLC (Diamond-like Carbon) chip is activated by an activating reagent, a coupling reaction of an allergen or a peptide containing an allergen epitope is performed and a specimen (such as saliva, nasal discharge or lacrimal fluid) subjected to pressure filtration with a low protein adsorptive filter is subsequently brought into contact with an allergen determination chip subjected to a washing and blocking procedure against an unreacted active group, and an allergen recognition antibody in the specimen captured by the allergen determination chip is detected through an immunoassay using a labeled secondary antibody. At this time, as a washing liquid and/or a blocking liquid to be used in the washing and blocking procedure, a glycine-containing liquid is used.

IPC Classes  ?

  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor
  • G01N 21/78 - Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
  • G01N 33/531 - Production of immunochemical test materials
  • G01N 33/543 - ImmunoassayBiospecific binding assayMaterials therefor with an insoluble carrier for immobilising immunochemicals

84.

METHOD OF SEPARATING AND DISTINGUISHING WALNUT FROM PECAN NUT

      
Application Number JP2008051454
Publication Number 2008/093753
Status In Force
Filing Date 2008-01-30
Publication Date 2008-08-07
Owner
  • Oriental Yeast Co., Ltd. (Japan)
  • NISSIN FOODS HOLDINGS CO., LTD. (Japan)
Inventor
  • Yano, Takeo
  • Sakai, Yumiko
  • Uchida, Kouji
  • Nakao, Yoshiki
  • Ishihata, Kimie
  • Nakano, Shigeru
  • Yamada, Toshihiro

Abstract

[PROBLEMS] To newly develop a method whereby walnut can be conveniently, quickly and accurately separated and distinguished from pecan nut. [MEANS FOR SOLVING PROBLEMS] With the recent increase in the patients with walnut allergy and an increase in pecan nut imports in Japan, it has been urgently required to develop a method of distinguished walnut from pecan nut. Paying attention to chloroplast matK gene having a clarified gene sequence, a PCR method for specifically detecting a nut belonging to the family Juglandaceae is developed. To distinguish walnut from pecan nut, furthermore, pecan nut matK sequence is clarified and thus amethod of distinguished walnut from pecan nut with the use of a restriction enzyme is established.

IPC Classes  ?

  • C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
  • C12N 15/09 - Recombinant DNA-technology
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

85.

METHOD OF DETECTING MAMMARY CANCER CELLS

      
Application Number JP2007051723
Publication Number 2008/093427
Status In Force
Filing Date 2007-02-01
Publication Date 2008-08-07
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Kinugasa, Masahiro
  • Sugimoto, Michiyo
  • Uchida, Koji

Abstract

It is intended to provide a novel method of detecting mammary cancer cells with the use of a change in the expression level of a specific gene in a human mammary cancer tissue (or cells) as an indication. This object is achieved by providing a detection method characterized by comprising: (1) measuring the expression level of a gene having a specific base sequence in a human mammary cancer tissue (or cells); (2) measuring the expression level of the above-described gene in a normal human mammary gland tissue (or cells); and (3) comparing the values measured in the above (1) and (2) and thus detecting mammary cancer cell on the basis of the difference therein.

IPC Classes  ?

  • G01N 33/574 - ImmunoassayBiospecific binding assayMaterials therefor for cancer

86.

AGENT CONTAINING FUSED PROTEIN OF SOLUBLE RANKL WITH EPITOPE TAG

      
Document Number 02666415
Status In Force
Filing Date 2007-07-05
Open to Public Date 2008-04-17
Grant Date 2012-11-27
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

It is intended to provide a reagent containing a fused protein of RANKL with an epitope tag which has an improved effect of differentiating and activating osteoclasts compared with the case of using RANKL alone and an improved storage stability. An agent of differentiating and activating osteoclasts in vitro or in vivo which contains a fused protein of soluble RANKL with an epitope tag peptide as the active ingredient.

IPC Classes  ?

  • C12N 5/077 - Mesenchymal cells, e.g. bone cells, cartilage cells, marrow stromal cells, fat cells or muscle cells
  • C12N 5/078 - Cells from blood or from the immune system
  • A61K 38/17 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans
  • C07K 19/00 - Hybrid peptides
  • C12N 15/09 - Recombinant DNA-technology
  • C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
  • C07K 14/705 - ReceptorsCell surface antigensCell surface determinants

87.

OSTEOPENIA ANIMAL MODEL

      
Document Number 02666443
Status In Force
Filing Date 2007-10-11
Open to Public Date 2008-04-17
Grant Date 2012-02-14
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

The present invention provides a method for producing an osteopenia animal model by RANKL administration and an osteopenia animal model. Also, a method for producing an osteopenia animal model, comprising administering soluble RANKL or a fused protein of soluble RANKL with an epitope tag to a non-human animal so as to promote in vivo osteoclast differentiation and activation in the non-human animal, and an osteopenia animal model produced by the method are provided.

IPC Classes  ?

  • A01K 67/027 - New or modified breeds of vertebrates
  • A01K 67/00 - Rearing or breeding animals, not otherwise provided forNew or modified breeds of animals
  • G01N 33/15 - Medicinal preparations
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

88.

BONE LOSS MODEL ANIMAL

      
Application Number JP2007063871
Publication Number 2008/044379
Status In Force
Filing Date 2007-07-05
Publication Date 2008-04-17
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

It is intended to provide a method of constructing a bone loss model animal by administering RANKL and a bone loss model animal. Namely, a method of constructing a bone loss model animal which comprises administering soluble RANKL or a fused protein of soluble RANKL with an epitope tag to a nonhuman animal and thus promoting the differentiation and activation of osteoclasts in the body of the nonhuman animal; and a bone loss model animal constructed by this method.

IPC Classes  ?

  • A01K 67/027 - New or modified breeds of vertebrates
  • C12Q 1/02 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving viable microorganisms
  • G01N 33/15 - Medicinal preparations
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing
  • C07K 1/22 - Affinity chromatography or related techniques based upon selective absorption processes
  • C07K 14/47 - Peptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from animalsPeptides having more than 20 amino acidsGastrinsSomatostatinsMelanotropinsDerivatives thereof from humans from vertebrates from mammals
  • C07K 14/475 - Growth factorsGrowth regulators
  • C07K 19/00 - Hybrid peptides
  • C12N 15/12 - Genes encoding animal proteins
  • C12P 21/02 - Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione

89.

OSTEOPENIA MODEL ANIMAL

      
Application Number JP2007070309
Publication Number 2008/044797
Status In Force
Filing Date 2007-10-11
Publication Date 2008-04-17
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

Disclosed are: a method for producing an osteopenia model animal by administering RANKL; and an osteopenia model animal. Specifically disclosed are: a method for producing an osteopenia model animal, which comprises administering soluble RANKL or a fusion protein of soluble RANKL and an epitope tag to a non-human animal to stimulate the differentiation and activation of an osteoclast in the non-human animal; and an osteopenia model animal produced by the method.

IPC Classes  ?

  • A01K 67/027 - New or modified breeds of vertebrates
  • A01K 67/00 - Rearing or breeding animals, not otherwise provided forNew or modified breeds of animals
  • G01N 33/15 - Medicinal preparations
  • G01N 33/50 - Chemical analysis of biological material, e.g. blood, urineTesting involving biospecific ligand binding methodsImmunological testing

90.

REAGENT CONTAINING FUSED PROTEIN OF SOLUBLE RANKL WITH EPITOPE TAG

      
Application Number JP2007063869
Publication Number 2008/044378
Status In Force
Filing Date 2007-07-05
Publication Date 2008-04-17
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Tomimori, Yoshiya
  • Yasuda, Hisataka

Abstract

It is intended to provide a reagent containing a fused protein of RANKL with an epitope tag which has an improved effect of differentiating and activating osteoclasts compared with the case of using RANKL alone and an improved storage stability. An agent of differentiating and activating osteoclasts in vitro or in vivo which contains a fused protein of soluble RANKL with an epitope tag peptide as the active ingredient.

IPC Classes  ?

91.

DETECTION OF INFLAMMATORY DISEASE AND COMPOSITION FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASE

      
Document Number 02651597
Status In Force
Filing Date 2006-05-12
Open to Public Date 2007-11-22
Grant Date 2013-02-05
Owner
  • KEIO UNIVERSITY (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Maruyama, Kenta
  • Matsuo, Koichi
  • Yasuda, Hisataka

Abstract

A novel method for detection of an inflammatory disease and a novel composition for prevention or treatment of an inflammatory disease are provided. The method for detection of an inflammatory disease comprises using RANKL and/or OPG as a marker in a biological sample. The composition for prevention or treatment of an inflammatory disease comprises RANKL and/or M-CSF as an active ingredient.

IPC Classes  ?

  • C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
  • A61P 37/00 - Drugs for immunological or allergic disorders
  • C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
  • C12N 15/09 - Recombinant DNA-technology
  • G01N 33/483 - Physical analysis of biological material
  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor

92.

DETECTION OF INFLAMMATORY DISEASE AND COMPOSITION FOR PREVENTION OR TREATMENT OF INFLAMMATORY DISEASE

      
Application Number JP2006309602
Publication Number 2007/132512
Status In Force
Filing Date 2006-05-12
Publication Date 2007-11-22
Owner
  • KEIO UNIVERSITY (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Maruyama, Kenta
  • Matsuo, Koichi
  • Yasuda, Hisataka

Abstract

Disclosed are a novel method for detecting an inflammatory disease and a novel composition for the prevention or treatment of an inflammatory disease. A method for detecting an inflammatory disease using RANKL and/or OPG in a biological sample as a marker; and a composition for the prevention or treatment of an inflammatory disease comprising RANKL and/or M-CSF as an active ingredient.

IPC Classes  ?

  • C12Q 1/00 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions
  • A61K 38/00 - Medicinal preparations containing peptides
  • A61P 31/00 - Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
  • A61P 37/00 - Drugs for immunological or allergic disorders
  • C07K 16/28 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
  • C12N 15/09 - Recombinant DNA-technology
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids
  • G01N 33/483 - Physical analysis of biological material
  • G01N 33/53 - ImmunoassayBiospecific binding assayMaterials therefor

93.

GENE GROUP APPLICABLE TO CANCER PROGNOSTICATION

      
Application Number JP2007051800
Publication Number 2007/088971
Status In Force
Filing Date 2007-02-02
Publication Date 2007-08-09
Owner
  • MessengerScape Co., Ltd. (Japan)
  • ORIENTAL YEAST CO., LTD. (Japan)
  • National Institute of Radiological Sciences (Japan)
Inventor
  • Saito, Toshiyuki
  • Mikami, Yoji
  • Kinugasa, Masahiro
  • Mori, Kazuya
  • Sugimoto, Michiyo
  • Uchida, Koji

Abstract

It is intended to provide a novel method for determining the possibility of lymph node metastasis of breast cancer using a difference of expression level of a specific gene between a human metastatic breast cancer tissue (or cell) and a nonmetastatic breast cancer tissue (or cell) as an index. For this purpose, the method characterized by: (1) measuring the expression level of a gene having a specific base sequence in a human metastatic breast cancer tissue (or cell); (2) measuring the expression level of the gene in a human nonmetastatic breast cancer tissue (or cell); and (3) comparing the measured values of (1) and (2) and determining the possibility of lymph node metastasis of breast cancer based on the difference is provided.

IPC Classes  ?

  • C12N 15/00 - Mutation or genetic engineeringDNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purificationUse of hosts therefor
  • C12N 15/09 - Recombinant DNA-technology
  • C12Q 1/68 - Measuring or testing processes involving enzymes, nucleic acids or microorganismsCompositions thereforProcesses of preparing such compositions involving nucleic acids

94.

TECHNIQUE FOR CULTURE OF MESENCHYMAL STEM CELL UTILIZING LAMININ-5

      
Application Number JP2006316545
Publication Number 2007/023875
Status In Force
Filing Date 2006-08-17
Publication Date 2007-03-01
Owner
  • ORIENTAL YEAST CO., LTD. (Japan)
  • YOKOHAMA CITY UNIVERSITY (Japan)
  • KIHARA MEMORIAL YOKOHAMA FOUNDATION FOR THE ADVANCEMENT OF LIFE SCIENCES (Japan)
Inventor
  • Miyazaki, Kaoru
  • Hashimoto, Junko
  • Kariya, Yoshinobu

Abstract

Disclosed is a substance capable of enhancing at least one activity selected from the group consisting of growth activity, adhesion activity and extension activity of a mesenchymal stem cell. The substance comprises laminin-5 as an active ingredient. Also disclosed are a method for cultivation of a mesenchymal stem cell, a method for isolation of a mesenchymal stem cell, and a culture medium, vessel or sheet for use in the cultivation of a mesenchymal stem cell.

IPC Classes  ?

  • A61P 19/02 - Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
  • A61P 19/10 - Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
  • A61P 21/00 - Drugs for disorders of the muscular or neuromuscular system
  • C12M 3/00 - Tissue, human, animal or plant cell, or virus culture apparatus
  • C12N 15/09 - Recombinant DNA-technology
  • C12N 5/02 - Propagation of single cells or cells in suspensionMaintenance thereofCulture media therefor
  • C12N 5/0775 - Mesenchymal stem cellsAdipose-tissue derived stem cells
  • A61K 35/12 - Materials from mammalsCompositions comprising non-specified tissues or cellsCompositions comprising non-embryonic stem cellsGenetically modified cells

95.

SACCHAROMYCES SPECIES FD 612 AND THE UTILIZATION THEREOF

      
Document Number 01193212
Status In Force
Filing Date 1983-05-20
Grant Date 1985-09-10
Owner ORIENTAL YEAST CO., LTD. (Japan)
Inventor
  • Nakatomi, Yasuo
  • Saito, Hiraku
  • Umeda, Fumio
  • Nagashima, Akihiro

Abstract

ABSTRACT Saccharomyces FD 612 is very useful as a baker's yeast which has been produced by many selections and matings started from three kinds of yeasts, since it has an excellent freeze-resistance and can produce bread with a good quality even after the freeze-storage of a dough.

IPC Classes  ?

  • C12N 1/18 - Baker's yeastBrewer's yeast
  • A21D 8/04 - Methods for preparing doughTreating dough prior to baking treating dough with microorganisms or enzymes