[Summary]
[Summary]
[Purpose] The invention provides a novel therapeutic agent or prophylactic agent for cognitive disorders.
[Summary]
[Purpose] The invention provides a novel therapeutic agent or prophylactic agent for cognitive disorders.
[Solution Means] The invention provides an antibody that participates in antigen-antibody reaction specifically with tau protein that has been phosphorylated in the vicinity of Ser413 of SEQ ID NO: 1, and a therapeutic agent or prophylactic agent for cognitive disorders comprising as an active ingredient a peptide that has been phosphorylated in the vicinity of Ser413.
C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
C07K 14/47 - Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from humans from vertebrates from mammals
2.
Three-dimensional display apparatus, three-dimensional display system, head up display, head up display system, three-dimensional display apparatus design method, and mobile object
A three-dimensional display apparatus comprises a display panel (display element) and a parallax barrier (optical element). The display panel displays a left-eye image and a right-eye image respectively in first subpixels and second subpixels. The parallax barrier transmits at least part of the left-eye image toward the left eye, and at least part of the right-eye image toward the right eye. A first certain number of the first subpixels and of the second subpixels are each successively arranged in each column. A region in which the first subpixels are arranged and a region in which the second subpixels are arranged are displaced from each other by a second certain number between two adjacent columns. The first certain number is greater than the second certain number and is not a multiple of the second certain number.
G02B 30/28 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving lenticular arrays involving active lenticular arrays
H04N 13/305 - Image reproducers for viewing without the aid of special glasses, i.e. using autostereoscopic displays using lenticular lenses, e.g. arrangements of cylindrical lenses
G02B 30/27 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving lenticular arrays
G02B 30/29 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving lenticular arrays characterised by the geometry of the lenticular array, e.g. slanted arrays, irregular arrays or arrays of varying shape or size
G02B 30/31 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving parallax barriers involving active parallax barriers
G02B 30/32 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving parallax barriers characterised by the geometry of the parallax barriers, e.g. staggered barriers, slanted parallax arrays or parallax arrays of varying shape or size
3.
KIT FOR DETECTING SARS-COV-2 ANTIBODIES AND DETECTION METHOD
MITSUBISHI HEAVY INDUSTRIES THERMAL SYSTEMS, LTD. (Japan)
OSAKA CITY UNIVERSITY (Japan)
NEWJEC INC. (Japan)
THE KANSAI ELECTRIC POWER CO., INC. (Japan)
MORIKAWA SAKUSEN INDUSTRIES CO., LTD. (Japan)
Inventor
Sakai, Masanobu
Fuchimoto, Takeshi
Sai, Rinnichi
Nakao, Masaki
Nakamura, Kazuhiro
Nakaso, Yasuhisa
Morikawa, Toshihide
Sakae, Shinsuke
Abstract
A geothermal heat utilization system (10) includes a pumping well (20), a water injection well (30), a pipe (13) having two ends which are immersed in water stored in the pumping well (20) and the water injection well (30) so as to connect the pumping well (20) and the water injection well (30) to each other, a pump (21) and a pump (31) which are respectively provided inside the pumping well (20) and the water injection well (30) and pump up stored water through the pipe (13), a valve (25) and a valve (35) which are respectively provided on a pressurization side of the pump (21) inside the pumping well (20) and a pressurization side of the pump (31) inside the water injection well (30), and a heat exchanger (14) which is configured to exchange heat with the pipe (13).
F24T 10/20 - Geothermal collectors using working fluid injected directly into the ground, e.g. using injection wells and recovery wells
5.
Three-dimensional display apparatus, three-dimensional display system, head up display, head up display system, three-dimensional display apparatus design method, and mobile object
A three-dimensional display apparatus comprises a display panel (display element) and a parallax barrier (optical element). The display panel displays a left-eye image and a right-eye image respectively in first subpixels and second subpixels. The parallax barrier transmits at least part of the left-eye image toward the left eye, and at least part of the right-eye image toward the right eye. A first certain number of the first subpixels and of the second subpixels are each successively arranged in each column. A region in which the first subpixels are arranged and a region in which the second subpixels are arranged are displaced from each other by a second certain number between two adjacent columns. The first certain number is greater than the second certain number and is not a multiple of the second certain number.
H04N 13/305 - Image reproducers for viewing without the aid of special glasses, i.e. using autostereoscopic displays using lenticular lenses, e.g. arrangements of cylindrical lenses
G02B 30/27 - Optical systems or apparatus for producing three-dimensional [3D] effects, e.g. stereoscopic images by providing first and second parallax images to an observer’s left and right eyes of the autostereoscopic type involving lenticular arrays
The present invention includes: a front-side positive trace (2P) disposed on a flexible substrate (5); a positive external connection line (12P) connected to the front-side positive trace (2P) to supply electric power; and LED chips (4) provided to the flexible substrate (5) and connected to the front-side positive trace (2P), wherein an electric resistance between the positive external connection line (12P) and one of the LED chips (4) which is farthest from the positive external connection line (12P) is less than an internal resistance of the one of the LED chips (4).
The present invention provides a means for treating and/or preventing peripheral nerve disorder by facilitating regeneration of peripheral nerves. Specifically, the present invention provides a composition for treating and/or preventing peripheral nerve disorder comprising a compound represented by the general formula (I):
3 is lower alkyl optionally substituted with halogen, lower alkoxy, or phenyl; condensed polycyclic hydrocarbon; or hydrogen.
A61K 31/27 - Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, e.g. meprobamate, carbachol, neostigmine
A61P 25/02 - Drugs for disorders of the nervous system for peripheral neuropathies
A61K 9/00 - Medicinal preparations characterised by special physical form
A61K 31/341 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
A61K 31/4402 - Non-condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
A retractor holds a surgical incision in a body in an opened state to ensure a surgical field in small-incision endoscopic surgery, and includes a base body that is a thin plate made of tin having a purity of not less than 99.9% and has an elongated rectangular shape in an extended state of the base body. The retractor, in an extended form in a rectangular shape or in a rounded form in a small shape, can be inserted from a small incision wound into the body, and can easily be delivered to the surgical incision in the body by a surgical instrument. The base body is bent and deformed into a desired shape by the surgical instrument and is applied to the surgical incision in the body, so that the surgical incision can be held in an opened state so as to ensure the surgical field.
A filler has one or more filler elements, and the filler elements have a main body part having a flat liquid film-forming face and one or more wall parts vertically disposed with respect to the liquid film-forming face along a straight line. Side faces of the wall parts have inclined surfaces inclined at a prescribed angle with respect to the film-forming face, at the surface of the film formed by a liquid on the film-forming face.
A fatigue degree determination device includes a fatigue degree determination unit. A first biological heart rate is acquired while a user is awake and at rest, based on a biological heart rate measured from the user. A second biological heart rate is acquired while the user is sleeping, based on the biological heart rate measured from the user. The fatigue degree determination unit determines a fatigue degree of the user, based on information read out from a storage medium, the first biological heart rate and the second biological heart rate. The storage medium stores the information in which a degree of change of one biological heart rate relative to the other biological heart rate of a biological heart rate while a person is awake and at rest and a biological heart rate while the person is sleeping and a fatigue degree are associated with each other.
Provided is a blind bolt which can be fastened with a high joining strength and easily unfastened by using commercially available tools. This blind bolt for fastening an attachment member (71) having attachment holes (72, 73) formed therein and an attachment target member (70) is provided with: a bolt (10) having a head section (11) having a large diameter, a cylindrical section (13) adjacent to the head section, and a male thread section (15); a washer (20); an outer nut (30) having a first end surface (35), a second end surface (36), and an outer nut hole; an expanded-diameter sleeve (40) having a first curved section, which has a central portion that bulges outward, and a second curved section, which is thicker than the first curved section and has a central section that bulges outward; and an inner nut (50) having an inner nut end section which can be inserted into the outer nut hole of the outer nut, a cylindrical inner nut cylinder section (53), an inner nut head section (55) having a larger diameter than the cylinder part, an inner nut hole (52) into which the cylindrical section of the bolt can be inserted, and a female thread section (57) that is screwed with the male thread section of the bolt.
F16B 13/06 - Dowels or other devices fastened in walls or the like by inserting them in holes made therein for that purpose with parts gripping in the hole or behind the reverse side of the wall after inserting from the front combined with expanding sleeve
F16B 13/04 - Dowels or other devices fastened in walls or the like by inserting them in holes made therein for that purpose with parts gripping in the hole or behind the reverse side of the wall after inserting from the front
F16B 37/04 - Devices for fastening nuts to surfaces, e.g. sheets, plates
12.
DEVICE, METHOD, AND PROGRAM FOR VISUALIZING VASCULAR PLEXUS OF SKIN
A device 1 according to an embodiment of the present invention is provided with: optical mechanisms 8, 10 for causing light from a light source 2 to be guided to and scanned along tissue of skin S; a control/calculation unit 14 which controls the driving of the optical mechanisms 8, 10, acquires tomographic images of the skin S by processing optical interference signals from an optical system, and calculates a vascular plexus on the basis of the tomographic images; and a display device 16 for displaying an image of the vascular plexus. The control/calculation unit 14 calculates autocorrelation values for coordinates of a region corresponding to the epidermis in the plurality of acquired tomographic images, calculates autocorrelation values for coordinates of a region corresponding to the dermis by excluding a combination of tomographic images corresponding to a predetermined low autocorrelation among the calculated autocorrelations, and identifies, as blood vessels or blood vessel candidates, coordinates where the autocorrelation values in the region corresponding to the dermis are in a predetermined low correlation range, to calculate the vascular plexus.
A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
13.
DEVICE, METHOD, AND PROGRAM FOR VISUALIZING VASCULAR PLEXUS OF SKIN
A device according to an embodiment of the present invention is provided with: optical mechanisms for causing light from a light source to be guided to and scanned along tissue of skin; a control/calculation unit which controls the driving of the optical mechanisms, acquires tomographic images of the skin by processing optical interference signals from an optical system, and calculates a vascular plexus on the basis of the tomographic images; and a display device for displaying an image of the vascular plexus. The control/calculation unit expresses thickness in the vascular plexus by superimposing, on the image of the vascular plexus, an identification display based on the sizes of blood vessel radii r at coordinates corresponding to each blood vessel, when the blood vessel radius r refers to the radius required to cause the coordinates corresponding to one blood vessel to reach the periphery, with the coordinates corresponding to another blood vessel identified as a blood vessel during calculation of the vascular plexus at the centre.
A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
14.
DEVICE, METHOD, AND PROGRAM FOR VISUALIZING VASCULAR PLEXUS OF SKIN
A device according to an embodiment of the present invention is provided with: optical mechanisms for causing light from a light source to be guided to and scanned along tissue of skin; a control/calculation unit which controls the driving of the optical mechanisms, acquires tomographic images of the skin by processing optical interference signals from an optical system, and calculates a vascular plexus on the basis of the tomographic images; and a display device for displaying an image of the vascular plexus. The control/calculation unit sets a reference profile obtained by approximating functions of a luminance profile of the acquired tomographic images in the depth direction, calculates, as outlier values V for the luminance values in the depth direction of the tomographic images, the differences between the luminance values on the reference profile and the actual luminance values, and identifies, as blood vessels or blood vessel candidates, coordinates having outlier values V in a predetermined blood vessel determination range, to calculate the vascular plexus.
A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
A61B 5/00 - Measuring for diagnostic purposes ; Identification of persons
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
This three-dimensional display device comprises a display panel and an optical element. The display panel has a display surface having a shape that is at least a part of the shape of a cylindrical plane around the center axis. Left sub-pixel groups and right sub-pixel groups are arrayed in a grid pattern along the direction of the center axis and the circumferential direction around the center axis in the display surface. The left sub-pixel groups and the right sub-pixel groups are alternately arrayed in the circumferential direction. Each left sub-pixel group has sub pixels for displaying an image for a left eye. Each right sub-pixel group has sub pixels for displaying an image for a right eye. The optical element includes: a plurality of light-reduction regions which are arranged along the display surface 51 and in which image light from the display surface is reduced or blocked; and a plurality of light-transmissive regions through each of which the image light is transmitted at a higher transmittance than that of each light-reduction region. The plurality of light-reduction regions and the plurality of light-transmissive regions are alternately arrayed along the circumferential direction so as to be adjacent to each other. The light-reduction regions and the light-transmissive regions are alternately arrayed at approximately the same interval in the circumferential direction. This interval is defined on the basis of: the radius R of curvature of an arc formed by a cross section, of the display surface, that is taken along a plane orthogonal to the direction of the center axis; an image pitch that is the interval at which the left sub-pixel groups and the right sub-pixel groups are arranged; and the gap between the display surface and the optical element.
The output system pertaining to an aspect of the present invention is provided with a magnet disposed on an axis of an indicating needle of a meter, first and second magnetic sensors each configured so as to have a sensitivity axis direction, and an output unit configured so as to output indicated value information generated on the basis of detection values of the magnetic sensors. First and second directions are set so as to intersect on the axis of the indicating needle, the first magnetic sensor is disposed so that the sensitivity axis direction thereof is aligned with the first direction, and the second magnetic sensor is disposed so that the sensitivity axis direction thereof is aligned with the second direction.
G01D 5/16 - Mechanical means for transferring the output of a sensing member; Means for converting the output of a sensing member to another variable where the form or nature of the sensing member does not constrain the means for converting; Transducers not specially adapted for a specific variable using electric or magnetic means influencing the magnitude of a current or voltage by varying resistance
G01D 13/26 - Pointers, e.g. settable pointer adapted to perform a further operation, e.g. making electrical contact
17.
SIGNAL PROCESSING SYSTEM AND SIGNAL PROCESSING METHOD
A signal processing system according to one aspect of the present invention comprises: a receiving device that receives a signal; and a plurality of detection devices that detect the components of the differing frequencies of a current to be analyzed that flows to the receiving device corresponding to the received signal. Each detection device comprises: a magnetic element configured such that a resistance value changes according to a magnetic field generated by the current to be analyzed; a current source that outputs an alternating current of a predetermined frequency to the magnetic element; a filter that allows a current of a component of the sum or difference of the frequency of the current to be analyzed and the predetermined frequency to pass if the frequency of the signal is a specific frequency; and a detector that is disposed between the magnetic element and the filter and that detects a current flowing to a circuit including the magnetic element.
G01R 23/165 - Spectrum analysis; Fourier analysis using filters
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
G01R 19/00 - Arrangements for measuring currents or voltages or for indicating presence or sign thereof
18.
PHARMACEUTICAL COMPOSITION FOR NASAL ADMINISTRATION
The purpose of the present invention is to provide a dosing technique for rifampicin, the technique being capable of long-term administration by enhancing the direct transfer of rifampicin to the brain and by suppressing the first pass to the liver. This pharmaceutical composition for nasal administration, which contains, as an active ingredient, rifampicins selected from the group consisting of rifampicin, derivatives thereof, and salts thereof, and is used for the prevention or treatment of dementia, is capable of long-term administration by enhancing the direct transfer of rifampicin to the brain and suppressing the first pass to the liver.
A61K 31/496 - Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
19.
DEVICE AND METHOD FOR TOMOGRAPHIC VISUALIZATION OF TISSUE VISCOELASTICITY
A device 1 in an embodiment of the present invention includes an optical system employing optical coherence tomography (OCT), and performs tomographic visualization of the viscoelasticity of tissue in a target S. This device is provided with: an optical mechanism 8 for guiding and scanning light from a light source 2 into the tissue of the target S; a loading device 13 for imparting deformation energy to the tissue; a control and computing unit 14 which controls the drive of the loading device 13 and the optical mechanism 8, and, by processing an optical interference signal resulting from the optical system by means of the drive of the loading device 13 and the optical mechanism 8, computes a tomographic distribution of the viscoelasticity of the tissue; and a display device 16 which effects a display in such a way that the viscoelasticity of the tissue can be visualized in a tomographic manner. The loading device 13 is a non-contact loading device which loads the tissue with acoustic radiation pressure by outputting ultrasonic waves toward a focal point set inside the target S.
G01N 21/17 - Systems in which incident light is modified in accordance with the properties of the material investigated
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 8/08 - Detecting organic movements or changes, e.g. tumours, cysts, swellings
20.
Geothermal heat utilization system and geothermal heat utilization method
MITSUBISHI HEAVY INDUSTRIES THERMAL SYSTEMS, LTD. (Japan)
THE KANSAI ELECTRIC POWER CO., INC. (Japan)
OSAKA CITY UNIVERSITY (Japan)
NEWJEC INC. (Japan)
Inventor
Sakai, Masanobu
Fuchimoto, Takeshi
Sai, Rinnichi
Nakaso, Yasuhisa
Sakae, Shinsuke
Nakao, Masaki
Nishioka, Masatoshi
Nakamura, Kazuhiro
Abstract
A geothermal heat utilization system includes a heat source well facility, a heat source device having a refrigeration cycle including a compressor, a condenser, an expanded portion, and an evaporator, a primary refrigerant circuit that is connected to a first unit which is one of the condenser and the evaporator of the heat source device, heat exchange being able to be performed between the first unit and the well-side pipe, a secondary refrigerant circuit that is connected to a second unit which is the other of the condenser and the evaporator of the heat source device, heat exchange being able to be performed between the second unit and a load, and a mode switching unit that switches between a cold heat storage operation mode in which the primary refrigerant circuit is connected to the evaporator and the secondary refrigerant circuit is connected to the condenser and a cold heat discharge operation mode in which the primary refrigerant circuit is connected to the condenser and the secondary refrigerant circuit is connected to the evaporator.
MITSUBISHI HEAVY INDUSTRIES THERMAL SYSTEMS, LTD. (Japan)
OSAKA CITY UNIVERSITY (Japan)
NEWJEC INC. (Japan)
THE KANSAI ELECTRIC POWER CO., INC. (Japan)
MORIKAWA SAKUSEN INDUSTRIES CO., LTD. (Japan)
Inventor
Sakai Masanobu
Fuchimoto Takeshi
Sai Rinnichi
Nakao Masaki
Nakamura Kazuhiro
Nakaso Yasuhisa
Morikawa Toshihide
Sakae Shinsuke
Abstract
This geothermal heat utilization system (10) is provided with: a pumping well (20) and a water injection well (30); a pipe (13) both ends of which are immersed in storage water which is in the pumping well (20) and the water injection well (30), so as to connect the pumping well (20) and the water injection well (30); a pump (21) and a pump (31) which are respectively provided in the pumping well (20) and in the water injection well (30), and pump up the storage water through the pipe (13); a valve (25) and a valve (35) which are respectively provided on a pressurizing side of the pump (31) in the water injection well (30) and on a pressurizing side of the pump (21) in the pumping well (20); and a heat exchanger (14) for exchanging heat with the pipe (13).
Provided is a novel diarylethene compound which is discolored when irradiated with ultraviolet light, and which does not change color much under visible light after the discoloration. A diarylethene compound according to the present invention is represented by general formula (1).
C07D 409/14 - Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
This 3D display device 3 comprises a display panel 5 (display element) and a parallax barrier 6 (optical element). The display panel 5 of the 3D display device 3 displays a left eye image and a right eye image on first subpixels 11L and second subpixels 11R, respectively. The parallax barrier 6 allows at least a part of the left eye image to be transmitted to the left eye of a user, and allows at least a part of the right eye image to be transmitted to the right eye. A first prescribed number of the first subpixels 11L and second subpixels 11R is aligned continuously in respective rows. The regions in which the first subpixels 11L and second subpixels 11R are aligned are offset by a second prescribed number in adjacent rows. The first prescribed number is larger than the second prescribed number and is not a multiple of the second prescribed number.
Provided is a diarylethene compound which does not require an additional component such as an acid for color development, while suitably exerting functions such as a switching function (coloring by means of ultraviolet light irradiation), excellent stability of a colored state under visible light, and irreproducible decoloring due to temperature increase in a low temperature environment (for example, room temperature or less). A diarylethene compound which is represented by general formula (1).
Provided are a fatigue assessment device, fatigue assessment method, fatigue assessment program, and biological information measurement device, which make it possible to accurately establish a degree of fatigue at a light load. A control unit 30 of a biological information measurement device 100 is provided with: a first biological beat rate acquisition unit 34 for acquiring a first biological beat rate of when a user is awake and at rest on the basis of a biological beat rate measured from the user; a second biological beat rate acquisition unit 35 for acquiring a second biological beat rate of when the user is sleeping on the basis of a biological beat rate measured from the user; and a fatigue assessment unit 36 for assessing the user's fatigue on the basis of information read out from a storage medium 40 and on the basis of the first biological beat rate and second biological beat rate, the storage medium 40 storing information associating together degrees of fatigue and degrees of change of one biological beat rate relative to the other biological beat rate from among the biological beat rate of when the person is awake and at rest and the biological beat rate of when the person is sleeping.
The filler has one or more thin-layer filler elements that are installed upright, the filler element having a main body portion with a planar liquid film formation surface, and one or more wall portions that are provided upright relative to the liquid film formation surface along a linear direction. The side surface of each wall portion has a curved portion at the base thereof connected to the liquid film formation surface, the curved portion curving so as to continue into the liquid film formation surface.
B01J 19/32 - Packing elements in the form of grids or built-up elements for forming a unit or module inside the apparatus for mass or heat transfer
B01J 10/00 - Chemical processes in general for reacting liquid with gaseous media other than in the presence of solid particles; Apparatus specially adapted therefor
[Problem] To facilitate ease in maintaining a surgical field as a surgeon sees fit, to facilitate flexibly maintaining and changing the surgical field based on a surgical site or the situation of an operation, and to simplify moving to a required position of the surgical site and post-operative extraction. [Solution] Provided is a retractor 1 which, in small-incision endoscopic surgery, retains an incision site within a body in an open state and maintains an operating field. The retractor 1 comprises a rectangular substrate 2, which is a thin plate composed of tin having 99.9% or higher purity, and which is long and thin when in an extended state. It is possible to insert the retractor 1 within the body via a small incision, and to easily deliver the retractor 1 with a surgical instrument to an incision site within the body, in the rectangular extended form or a tightly rolled-up form. By fitting the retractor 1 into the incision site within the body in a form in which said retractor 1 has been bent and deformed into a required shape with the surgical instrument, it is possible to retain the incision site in the open state so as to maintain the operating field. Given that the substrate 2 is composed of tin having 99.9% or higher purity, the retractor 1 is particularly flexible, and it is possible to easily bend and deform the substrate 2 into a required form using the surgical instrument.
The present invention is provided with a surface positive wiring (2P) formed on a flexible substrate (5), an external positive connection wire (12P) connected to the surface positive wiring (2P) to supply electric power, and a plurality of LED chips (4) disposed on the flexible substrate (5) and connected to the surface positive wiring (2P), the electrical resistance between the LED chip (4) disposed farthest from the external positive connection wire (12P) and the external positive connection wire (12P) being less than the internal resistance of the LED chip (4).
This skin diagnosing device (1) is provided with: an optical unit (2) including an optical system that employs optical coherence tomography (OCT); an optical mechanism (4) for causing light from the optical unit (2) to be guided to and scanned along the skin (S); a load device (5) for imparting deformation energy to the skin (S); a control arithmetic unit (6) which controls driving of the load device (5) and the optical mechanism (4), processes an optical interference signal output from the optical unit (2) in accordance with the driving of the load device (5) and the optical mechanism (4), in order to compute a tomographic distribution of a predetermined state value relating to the skin (S), and computes an evaluation value of the skin (S) on the basis of the tomographic distribution; and a display device (74) which displays the evaluation value of the skin (S). The control arithmetic unit (6) computes, as the state value, a mechanical property and a blood flow state of the skin (S), and computes the evaluation value by associating the mechanical property with the blood flow state at a tomographic position in the skin (S).
A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
32.
COMPOSITION FOR TREATMENT AND/OR PREVENTION OF PERIPHERAL NERVE DISORDER
Provided is a means for treating and/or preventing a peripheral nerve disorder through promotion of regeneration of peripheral nerves. More specifically, provided is a composition for treatment and/or prevention of a peripheral nerve disorder that contains the compound represented by formula (I) (wherein: R1 represents a lower alkyl group substituted by a lower alkoxy group, a lower alkyl group substituted by a heterocyclic group, a heterocyclic group, or a group represented by formula (IIa) (wherein, R4 represents a lower alkyl group, R5 represents a lower alkylene group, and m represents an integer of 1-6); R2 represents a lower alkyl group optionally substituted by a phenyl group; and R3 represents a lower alkyl group (optionally substituted by a halogen, a lower alkoxy group, or a phenyl group), a condensed polycyclic hydrocarbon group, or a hydrogen atom).
A61K 31/27 - Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, e.g. meprobamate, carbachol, neostigmine
A61K 31/341 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
According to an aspect of the present invention, a drive control system is provided that includes a transmitting apparatus and a plurality of drive control apparatuses and drives and controls a plurality of devices to be controlled, wherein the transmitting apparatus includes: a control information addition apparatus that frequency-multiplexes a plurality of control signals, and an electric wire that supplies power and the plurality of control signals to the plurality of drive control apparatuses.
H04B 3/54 - Systems for transmission via power distribution lines
H04B 3/56 - Circuits for coupling, blocking, or by-passing of signals
H04Q 9/00 - Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom
The purpose of the present invention is to provide a power storage device using an aqueous electrolyte that is safe even on the chance that there is damage during use and there is leakage from the cell housing. In specific terms, the purpose of the present invention is to provide a secondary cell that has excellent safety and also has excellent cycle characteristics. The present invention is an aqueous secondary cell for which at least one of the positive electrode and the negative electrode contains a compound (I) having a naphthalene diimide structure or a perylene diimide structure as an active material.
The present invention provides: DNA for intracellular penetration; a composition that includes said DNA and a target molecule to be introduced into a cell; a method for introducing the target molecule into the cell using said composition; and an agent and kit for introducing the target molecule into the cell, said agent and kit including said DNA. Provided is DNA for intracellular penetration, said DNA including an intracellular penetration region comprising the following base sequence: 5'-N1-N2-GG-N5-N6-N7-GGTGGT-N14-GGGG-N19-N20-G-N22-N23-TCG-N27-N28-N29-G-N31-AT-N34-N35-GTG-N39-N40-TCG-3' [Herein, N1 is deleted or is T, N2 is G or is deleted, N5 is C or T, N6 is G or C, N7 is G or T, N14 is G or C, N19 is A or G, N20 is G or A, N22 is deleted or is T, N23 is T or A, N27 is G, T, or A, N28 is T, A, or C, N29 is deleted or is T, N31 is G or A, N34 is G or is deleted, N35 is C or A, N39 is G or T, and N40 is G or A] (SEQ ID NO: 1).
A cancer invasion depth diagnosis system is provided with an endoscope, a micro-tomographic probe for acquiring an optical interference signal by emitting low-coherence light onto a tissue of interest where a tumor of interest is located, the micro-tomographic probe being inserted into the body together with the endoscope, and a determination unit for acquiring a tomographic image of the tissue of interest including the tumor of interest and blood flow velocity information in the blood vessels within the tomographic image, on the basis of the optical interference signal. The determination unit determines the invasion depth of the tumor of interest on the basis of the tomographic image and blood flow velocity information.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
This clamp-type ammeter has a flexible substrate of which an inner wall is configured to be able to deform into a substantially cylindrical shape. The clamp-type ammeter has a plurality of magnetic sensor elements disposed at the inner wall of the flexible substrate. The clamp-type ammeter has a tube of which one end is connected to the flexible substrate. The clamp-type ammeter has an operation unit that is connected to the other end of the tube and that can operate the deformation of the flexible substrate.
G01R 1/04 - Housings; Supporting members; Arrangements of terminals
G01R 1/20 - Modifications of basic electric elements for use in electric measuring instruments; Structural combinations of such elements with such instruments
G01R 1/22 - Tong testers acting as secondary windings of current transformers
G01R 15/06 - Voltage dividers having reactive components, e.g. capacitive transformer
G01R 15/16 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using capacitive devices
G01R 31/00 - Arrangements for testing electric properties; Arrangements for locating electric faults; Arrangements for electrical testing characterised by what is being tested not provided for elsewhere
G01R 33/00 - Arrangements or instruments for measuring magnetic variables
G01R 33/02 - Measuring direction or magnitude of magnetic fields or magnetic flux
G01R 19/00 - Arrangements for measuring currents or voltages or for indicating presence or sign thereof
G01R 35/00 - Testing or calibrating of apparatus covered by the other groups of this subclass
G08B 1/08 - Systems for signalling characterised solely by the form of transmission of the signal using electric transmission
G08B 21/00 - Alarms responsive to a single specified undesired or abnormal condition and not otherwise provided for
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
G01R 15/18 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using inductive devices, e.g. transformers
Provided are a crystal of reduced glutathione, said crystal being stable and easy to process, and a method for producing the same. According to the present invention, a crystal of a reduced glutathione metal salt is produced by suspending an amorphous of the reduced glutathione metal salt in a hydrophobic organic solvent and then adding water to the obtained suspension to thereby crystallize the reduced glutathione metal salt crystal.
C07K 5/037 - Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link the abnormal link being formed by the side chain of an alpha-amino acid, e.g. gamma-Glu, epsilon-Lys, glutathione
An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent comprising a compound represented by the general formula (I):
1 is lower alkyl substituted with lower alkoxy, lower alkyl substituted with a heterocyclic group, a heterocyclic group, or a group represented by the formula (IIa):
3 is lower alkyl optionally substituted with halogen, lower alkoxy, or phenyl; condensed polycyclic hydrocarbon; or hydrogen.
C07K 5/062 - Dipeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
C07K 5/083 - Tripeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
A61K 31/27 - Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, e.g. meprobamate, carbachol, neostigmine
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
An electric current measurement apparatus for measuring an electric current flowing in a conducting wire in a circuit to be measured, the electric current measurement apparatus characterized by having a magnetic element to which a drive electric current terminal and a measurement voltage terminal are provided, a holder for fixing a positional relationship of the conducting wire to a magnetic body, an electric current source capable of outputting at least one frequency of alternating electric current across the drive electric current terminal, a voltage meter for measuring a voltage across the measurement voltage terminal, and a low-pass filter provided between the measurement voltage terminal and the voltage meter.
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
G01R 19/00 - Arrangements for measuring currents or voltages or for indicating presence or sign thereof
G01R 21/08 - Arrangements for measuring electric power or power factor by using galvanomagnetic-effect devices, e.g. Hall-effect devices
41.
DRIVE CONTROL DEVICE AND DRIVE CONTROL SYSTEM COMPRISING SAME
According to an aspect of the present invention, provided is a drive control device for receiving, via an electric wire, a transmission signal generated by superimposing a plurality of control signals on power transmission voltage to control drive of a device to be controlled, wherein a detection frequency is set for the drive control device, one of the plurality of control signals is a control signal for controlling the device to be controlled, and the frequency thereof is close to the detection frequency. The drive control device is provided with: a drive voltage generation unit which generates a first drive voltage from the power transmission voltage of the transmission signal to drive the device to be controlled; a detection current generation unit which generates a detection current the frequency of which is the detection frequency; a magnetic element through which the detection current flows, and which generates an output corresponding to a result of multiplication of the detection current and a current flowing through the electric wire; and a signal processing unit which detects the control signal for controlling the device to be controlled from the output from the magnetic element, and controls the device to be controlled on the basis of the control signal.
H04Q 9/00 - Arrangements in telecontrol or telemetry systems for selectively calling a substation from a main station, in which substation desired apparatus is selected for applying a control signal thereto or for obtaining measured values therefrom
H04B 3/56 - Circuits for coupling, blocking, or by-passing of signals
42.
Medicinal composition for promoting synthesis of protoporphyrin IX
The object of the present invention is to elucidate the resistance mechanism in infections that show resistance to ALA-PDT that uses a single ALA, and to provide a novel treatment method against these infections. The present invention provides a pharmaceutical composition for promoting protoporphyrin IX production in ALA-PDT for treating infection, characterized in that it comprises a substance that promotes the conversion from coproporphyrinogen III to protoporphyrin IX.
A61K 31/195 - Carboxylic acids, e.g. valproic acid having an amino group
A61K 41/00 - Medicinal preparations obtained by treating materials with wave energy or particle radiation
A61K 45/06 - Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
A61K 31/197 - Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
A61K 31/198 - Alpha-amino acids, e.g. alanine, edetic acid (EDTA)
A61K 31/375 - Ascorbic acid, i.e. vitamin C; Salts thereof
Developed and provided is a method whereby a mutated gene that exists in a gene pool together with a number of wild type genes can be easily, economically and highly sensitively detected. Provided is a clamping probe that is capable of binding to target nucleic acid molecules at two regions, i.e., first and second nucleic acid complementary regions, and thus distinguishing these target nucleic acid molecules depending on a difference in complementarity to a wild type target nucleic acid molecule and complementarity to a mutated target nucleic acid molecule.
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
A61P 43/00 - Drugs for specific purposes, not provided for in groups
C12P 21/04 - Cyclic or bridged peptides or polypeptides, e.g. bacitracin
A cartilage diagnosis device 1 is provided with: an optical unit 2 including an OCT optical system; a probe including an optical mechanism connected to the optical unit 2 and configured so that a distal-end part thereof is insertable into an articular cavity, the optical mechanism for guiding light from the optical unit 2 to cartilage and causing the light to scan, and a weight mechanism capable of loading a predetermined weight on the cartilage; a control computation unit 6 for controlling driving of the weight mechanism and the optical mechanism, processing an optical interference signal outputted from the optical unit 2 on the basis of the driving of the weight mechanism and the optical mechanism, performing computation whereby a change in a predetermined dynamic characteristic quantity accompanying deformation in the cartilage due to weight loading is correlated with a tomographic position of the cartilage, and computing the degree of damage of cartilage tissue on the basis of the change in the dynamic characteristic quantity; and a display device 8 for displaying the degree of damage of the cartilage tissue in the form of a tomographic visualization.
A61B 10/00 - Other methods or instruments for diagnosis, e.g. for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
46.
STRESS VISUALIZATION DEVICE, AND MECHANICAL PROPERTY VALUE VISUALIZATION DEVICE
A control computation unit 114 changes the state of polarization by using an optical modulator 110, thereby shifting the phase of polarized waves illuminating an object W to be measured, and on the basis of phase differences among interference signals obtained during each phase shift of the of polarized waves, computes a spatial gradient of a phase difference stratigraphic distribution of the interference signals, and produces a visualized display on a display device 116, in which the stratigraphic distribution of the spatial gradient is associated with a stratigraphic distribution of stress. On the basis of the light interference signals, the control computation unit 114 computes a deformation rate vector distribution at a stratigraphic position of the object to be measured, and further computes a strain rate tensor stratigraphic distribution. A mechanical property value stratigraphic distribution is then computed on the basis of the stress stratigraphic distribution and the strain rate tensor stratigraphic distribution, and a visualized display is produced.
G01L 1/24 - Measuring force or stress, in general by measuring variations of optical properties of material when it is stressed, e.g. by photoelastic stress analysis
G01B 11/16 - Measuring arrangements characterised by the use of optical techniques for measuring the deformation in a solid, e.g. optical strain gauge
Provided is a wave-activated power generation system that can improve power generation efficiency while preserving quiet. The wave-activated power generation system is used with a seawall, dissipates the energy of waves, and generates power from the energy of the waves, wherein provided are a rotating-body row and a generator. The seawall is disposed in the water and has an impermeable wall but does not have a permeable front-wall on the offshore side of the impermeable wall. The rotating-body row consists of a plurality of rotating bodies which are, on the offshore side of the impermeable wall, arranged along the direction of extension of the impermeable wall in plan view. The generator converts the rotation energy of the plurality of rotating bodies into electrical power.
F03B 13/22 - Adaptations of machines or engines for special use; Combinations of machines or engines with driving or driven apparatus; Power stations or aggregates characterised by using wave or tide energy using wave energy using the flow of water resulting from wave movements, e.g. to drive a hydraulic motor or turbine
The heat medium transport paths are arranged between the first building and the second building and transport heat media that transport heat energy. A temperature distribution acquisition means acquires the temperature distribution of the heat media that have temperatures being different from each other in the heat medium transport paths and that are sequentially transported in a state of having a predetermined length in the transport direction in the heat medium transport paths. A control means receives a load request of an air conditioner of the first building, and when a heat medium having the heat energy that satisfies the load request received reaches the first building, based on the temperature distribution acquired by the temperature distribution acquisition means, the control means causes the air conditioner of the first building to take out the heat energy from the heat medium reached.
F24F 3/00 - Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
F24F 3/06 - Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the arrangements for the supply of heat-exchange fluid for the subsequent treatment of primary air in the room units
F24F 5/00 - Air-conditioning systems or apparatus not covered by group or
F24D 11/02 - Central heating systems using heat accumulated in storage masses using heat pumps
F24D 19/10 - Arrangement or mounting of control or safety devices
49.
ADHESIVE COMPOSITION AND EASILY DEGRADABLE ADHESIVE TAPE
An adhesive composition containing an acrylic polymer and an acid catalyst or an acid generator, wherein the acrylic polymer contains, as monomer components, a (meth)acrylate which has an alkyl group having 1-14 carbon atoms and a hydroxyl group-containing vinyl monomer; the content of the hydroxyl group-containing vinyl monomer is 10% by mass or more of the monomer components that constitute the acrylic polymer; and the acrylic polymer is an acrylic random polymer having a mass average molecular weight of 100,000 or more. This adhesive composition is able to achieve good adhesiveness and degradability.
C09J 133/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
Provided are a treatment method for an organic halogen compound, which allows the organic halogen compound to be efficiently decomposed without a large-scale treatment device or high operating cost, and a catalyst to be used for the treatment method. In the treatment method, an organic halogen compound is subjected to decomposition treatment by heating the organic halogen compound at a temperature of from 100° C. to 200° C. in the presence of a catalyst formed of copper oxide and hydrogen peroxide, to subject the organic halogen compound to a hydrothermal oxidation reaction utilizing a Fenton method.
A62D 3/35 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by hydrolysis
A62D 3/34 - Dehalogenation using reactive chemical agents able to degrade
This clamp-type ammeter has a flexible substrate of which an inner wall is configured in a manner able to deform into an approximately cylindrical shape. The clamp-type ammeter has a plurality of magnetic sensor elements disposed at the inner wall of the flexible substrate. The clamp-type ammeter has a tube of which one end is connected to the flexible substrate. The clamp-type ammeter has an operation unit that is connected to the other end of the tube and that can operate the deformation of the flexible substrate.
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
52.
POWER SENSOR, POWER SENSOR SYSTEM, AND REGENERATED POWER DETECTION DEVICE
This power sensor has a magnetic element that has a magnetic film, which is patterned in an oblique direction at a conductor, a first element terminal, which is connected to one end of the conductor, and a second element terminal, which is connected to the other end of the conductor, and during measurement, the first element terminal is connected to the subject device that is the subject of power measurement. The power sensor has: a measurement resistor of which one end is connected to the second element terminal of the magnetic element; and a detector that detects the DC component of the voltage between the first element terminal and the second element terminal. The magnetic element is disposed in a manner such that the direction from the first element terminal to the second element terminal during measurement is approximately parallel to the wire connected to the subject device.
H02P 27/06 - Arrangements or methods for the control of AC motors characterised by the kind of supply voltage using variable-frequency supply voltage, e.g. inverter or converter supply voltage using dc to ac converters or inverters
B60L 3/00 - Electric devices on electrically-propelled vehicles for safety purposes; Monitoring operating variables, e.g. speed, deceleration or energy consumption
B60L 7/16 - Dynamic electric regenerative braking for vehicles comprising converters between the power source and the motor
53.
CURRENT SENSOR ARRAY AND CURRENT VISUALIZATION DEVICE USING SAME
In a complex electrical circuit, the state of actual wire connection is when wire bundles are disposed vertically and horizontally. In such a state, displaying in which state current is currently flowing markedly increases on-site convenience. The present invention is a current sensor array characterized by having: a plurality of current sensors having magnetic elements and disposed on a line; a current circuit having an opening/closing switch and that flows current to the magnetic elements of the aforementioned current sensors; a drive circuit that successively opens/closes the opening/closing switch; and an amplifier that amplifies the output of the plurality of magnetic elements. The present invention is also a current visualization device characterized by being connected to the drive circuit and the amplifier, and by having a display unit that displays the output of the amplifier as a Z component and the position of the current sensor as an X component.
G01R 19/00 - Arrangements for measuring currents or voltages or for indicating presence or sign thereof
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
H01H 9/54 - Circuit arrangements not adapted to a particular application of the switching device and for which no provision exists elsewhere
H02B 3/00 - Apparatus specially adapted for the manufacture, assembly, or maintenance of boards or switchgear
t) connected to the pair of coupling ends (12), a voltage detector (15) for measuring a voltage between the measurement terminals (13), a low-pass filter (16) connected to the output of the voltage detector (15), a high-pass filter (17) connected to the output of the voltage detector (15), a rectifier (18) connected to the high-pass filter (17), and a divider (19) for dividing the output of the low-pass filter (16) and the output of the rectifier (18).
There is a limit on the miniaturization of electric leakage detecting apparatuses including a ring-shaped magnetic material. Any thicker electric wires increase the size of the ring-shaped magnetic material. Additionally, it is difficult to place the ring-shaped magnetic material around the electric wires that have already been placed. In light of the foregoing, an electric leakage apparatus is provided. The electric leakage detecting apparatus is to be installed on a pair of power source lines connecting a power source and a load, and includes: a pair of holders configured to hold the power source lines, respectively; a fixing means configured to fix the holders at a predetermined interval; a pair of magnetic elements each placed on each of the holders while being parallel to the power source lines; a detecting means configured to detect a difference between magneto-resistance effects of the magnetic elements; and a driving means configured to feed a drive current to the magnetic elements.
G01R 33/06 - Measuring direction or magnitude of magnetic fields or magnetic flux using galvano-magnetic devices
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
H01H 83/02 - Protective switches, e.g. circuit-breaking switches, or protective relays operated by abnormal electrical conditions otherwise than solely by excess current operated by earth fault currents
H02H 3/33 - Emergency protective circuit arrangements for automatic disconnection directly responsive to an undesired change from normal electric working condition, with or without subsequent reconnection responsive to phase angle between voltages or between currents involving comparison of the voltage or current values at corresponding points in different conductors of a single system, e.g. of currents in go and return conductors using summation current transformers
A power measurement apparatus configured to measure power consumed at a load, the apparatus includes a magnetic film module, an adjuster, a measurement resistance, and a voltage detector. The magnetic film module is arranged so that a longitudinal direction of the magnetic film module is parallel to current flowing in the load. The adjuster is configured to adjust a pass-frequency and a phase of a voltage at one terminal of the magnetic film module. The measurement resistance is serial-connected to the magnetic film module. The voltage detector is configured to detect a voltage between both terminals of the magnetic film module.
G01R 1/20 - Modifications of basic electric elements for use in electric measuring instruments; Structural combinations of such elements with such instruments
G01R 15/14 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
57.
ELECTRIC CURRENT MEASUREMENT APPARATUS AND ELECTRIC CURRENT MEASUREMENT METHOD
In order to measure power consumption or manage storage or consumption of electric power by an electrical device or electronic device, it is necessary to detect which and to what extent electric currents of each frequency component are flowing in a conducting wire through which overlapping electric currents of numerous frequencies are flowing. An electric current measurement apparatus for measuring an electric current flowing in a conducting wire in a circuit to be measured, the electric current measurement apparatus characterized by having a magnetic element to which a drive electric current terminal and a measurement voltage terminal are provided, a holder for fixing a positional relationship of the conducting wire to a magnetic body, an electric current source capable of outputting at least one frequency of alternating electric current across the drive electric current terminal, a voltage meter for measuring a voltage across the measurement voltage terminal, and a low-pass filter provided between the measurement voltage terminal and the voltage meter.
G01R 19/00 - Arrangements for measuring currents or voltages or for indicating presence or sign thereof
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
58.
Battery system and charge/discharge measuring apparatus
The present invention provides a charge/discharge measuring apparatus capable of appropriate charge/discharge management by accurately measuring a capacitance change of a secondary battery in charge/discharge. This charge/discharge measuring apparatus is configured such that a current from the secondary battery can be switched between a first connection circuit in which the secondary battery, a load resistor, and a conductor film are connected in series and a second connection circuit in which the secondary battery, a charger, and the conductor film are connected in series. Moreover, this charge/discharge measuring apparatus has a magnetic film arranged in parallel with the conductor film and connected in parallel with connection from the secondary battery to the load resistor and the charger and has a voltage detecting means for detecting a voltage change in the magnetic film.
G01R 31/36 - Arrangements for testing, measuring or monitoring the electrical condition of accumulators or electric batteries, e.g. capacity or state of charge [SoC]
H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
Magnetoresistance-type magnetic sensors have suffered from a problem in which an increase in the ambient temperature results in the degradation of the magnetic characteristics of the sensor magnetic film itself and thus results in the degradation of the sensor sensitivity. A magnetic sensor element with temperature correction according to the present invention is characterized by having a magnetic body exhibiting magnetoresistance, a pair of electrodes that oppose each other with the magnetic body therebetween and are for causing current to flow through the magnetic body, a vertical bias magnetic field addition means for generating a first bias magnetic field in the direction of the opposition of the electrodes, and a horizontal bias magnetic field addition means for generating a second bias magnetic field in the direction perpendicular to the vertical bias magnetic field addition means, and is characterized in that the temperature characteristic of the vertical bias magnetic field addition means is larger than the temperature characteristic of the horizontal bias magnetic field addition means.
[Problem] To clarify the resistance mechanism of ALA-PDT-resistant infections with the use of ALA alone to thereby provide a novel therapy method for these infections. [Solution] A medicinal composition for promoting the synthesis of protoporphyrin IX in ALA-PDT for treating infections, said medicinal composition being characterized by comprising a substance that promotes the conversion from coproporphyrinogen III into protoporphyrin IX.
A magnetoresistance effect magnetic sensor has a problem that the sensitivity thereof as a sensor lowers because the magnetic characteristic of a magnetic film itself lowers due to an increase in surrounding temperature. A sensor element characterized by comprising: a magnetic film having a magnetoresistance effect; a pair of electrodes facing each other with the magnetic film therebetween in order to pass a current through the magnetic film; a longitudinal bias magnetic field application magnet for generating a first bias magnetic field in a direction in which the electrodes face each other; and a lateral bias magnetic field application magnet for generating a second bias magnetic field in a direction perpendicular to the longitudinal bias magnetic field application magnet, and in that the temperature characteristic of the longitudinal bias magnetic field application magnet is larger than the temperature characteristic of the lateral bias magnetic field application magnet.
OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION (Japan)
Inventor
Matsumoto Akikazu
Sato Eriko
Morino Akinori
Abstract
The purpose of the present invention is to provide an easily removable adhesive tape that can be applied to a body for attaching and fasten between components, and that can be easily removed during disassembly, as well as an adhesive composition that can provide an easily removable adhesive tape. The adhesive composition of the present invention contains in the monomer components an acrylic copolymer containing 20 to 90 mol % of a (meth)acrylate obtained by reacting a (meth)acrylic acid and a vinyl ether. In the adhesive composition of the present invention, the acrylic copolymer preferably contains a (meth)acrylate having an alkyl group with 1 to 14 carbon atoms and at least one type of monomer having a hydroxyl group, as monomer components.
The present invention addresses the problem of providing a knock-in mouse that develops Osaka-mutation-mediated Alzheimer's disease through gene expression in normal physiological ranges. The problem is solved by a knock-in mouse as described below. A knock-in mouse into which a mutant amyloid precursor protein (mutant APP) gene described in (a) or (b), below, has been introduced, said mouse being homozygous for the mutant APP gene. (a) A mutant APP gene that codes a mutant murine amyloid-β protein and comprises the amino acid sequence represented by SEQ ID NO: 1. (b) A mutant APP gene that codes a polypeptide which induces the onset of Alzheimer's disease when expressed in mice, said gene comprising the amino acid sequence represented by SEQ ID NO: 1, in which one or more amino acids other than the 5th glutamine residue from the N terminal, the 10th phenylalanine residue from the N terminal and the 13th arginine residue from the N terminal has/have been substituted, deleted, inserted or added.
The purpose of the present invention is to provide an oligonucleotide structure and a method for regulating gene expression, said oligonucleotide structure and said method being capable of functioning exclusively in specific cells. The oligonucleotide structure is configured of three oligonucleotide chains including a trigger chain, an effector chain and a support chain, wherein: a part of each of the three oligonucleotide chains is base paired to a part of the other two chains so as to together form a Y-shaped structure; a part of the trigger chain and a part of the support chain each form a stem-loop structure; the effector chain is complementary to at least a part of a target gene transcription product; a part of the trigger chain is complementary to at least a part of a decay-inducing chain that is an RNA; the trigger chain and the support chain are DNAs; and base pairing of at least a part of the decay-inducing chain to a part of the trigger chain triggers the decay of the Y-shaped structure.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
A61K 31/711 - Natural deoxyribonucleic acids, i.e. containing only 2'-deoxyriboses attached to adenine, guanine, cytosine or thymine and having 3'-5' phosphodiester links
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61P 43/00 - Drugs for specific purposes, not provided for in groups
C07H 21/02 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
C07H 21/04 - Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
65.
Easily dismantlable adhesive composition and easily dismantlable adhesive tape
An easily dismantlable adhesive composition containing: an acrylic block polymer having a poly(meth)acrylate chain (A) formed of a carboxyl precursor group-containing (meth)acrylate monomer (a) and a poly(meth)acrylate chain (B) that contains, as monomer components, a (meth)acrylate (b) having an alkyl group having 1 to 14 carbon atoms and a polar group-containing monomer (c); and either an acid catalyst or an acid generator, makes it possible to achieve favorable adhesiveness and dismantlability and suppress stick-slip at the time of dismantlement.
C09J 153/00 - Adhesives based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Adhesives based on derivatives of such polymers
C09J 133/08 - Homopolymers or copolymers of acrylic acid esters
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
66.
Easily dismantlable adhesive agent composition and easily dismantlable adhesive tape
Suitable adhesive properties and dismantling properties can be obtained, and an interface between an adherent/an adhesive layer or an adhesive layer/a substrate can be suitably dismantlable by the easily dismantlable adhesive composition including an acrylate polymer including a (meth)acrylate monomer having a carboxyl precursor group, 2-ethyl hexyl acrylate, and a monomer having a polar group as a monomer, and an acid catalyst or an acid generator.
C09J 7/00 - Adhesives in the form of films or foils
C09J 133/08 - Homopolymers or copolymers of acrylic acid esters
C09J 133/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
C09J 153/00 - Adhesives based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Adhesives based on derivatives of such polymers
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
Provided is a mobile robot capable of reliably moving along an object surface produced from metal regardless of the shape of the object surface. A mobile robot moves over an object surface produced from metal, and is provided with: two or more casing parts which are disposed with a space therebetween; at least one output shaft which is rotatably supported by each of the casing parts; a wheel part which is disposed on each of both sides of each of the casing parts and rotationally driven by each of the output shafts; at least one driving part which rotationally drives the output shaft; and a coupling part which couples the casing parts adjacent to each other and at least part of which is elastically deformable. Each of the wheel parts is provided with a base coupled to the output shaft, a plurality of rod-shaped members radially projecting from the base, and magnets attached to the leading ends of the respective rod-shaped members.
B62D 57/024 - Vehicles characterised by having other propulsion or other ground-engaging means than wheels or endless track, alone or in addition to wheels or endless track with ground-engaging propulsion means, e.g. walking members specially adapted for moving on inclined or vertical surfaces
B25J 5/00 - Manipulators mounted on wheels or on carriages
B60B 19/00 - Wheels not otherwise provided for or having characteristics specified in one of the subgroups of this group
68.
INHIBITOR OF NUCLEIC ACID FOR REGULATING ACTIVITY OF RNAI MOLECULE
The purpose of the present invention is to provide a chemical capable of controlling a specific nucleic acid for regulating the activity of an RNAi molecule. Provided is an inhibitor of a nucleic acid for regulating the activity of an RNAi molecule, said inhibitor comprising a nucleic acid molecule that contains a base sequence being completely or sufficiently complementary to the base sequence of the single-stranded nucleic acid moiety of the target nucleic acid for regulating the activity of an RNAi molecule and, moreover, a base sequence being completely or sufficiently complementary to the base sequence of the double-stranded nucleic acid moiety thereof, and comprises at least DNA.
A61K 31/7088 - Compounds having three or more nucleosides or nucleotides
A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
A61P 43/00 - Drugs for specific purposes, not provided for in groups
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
An electrical power meter that utilizes a magnetic thin film is required to be mountable to wiring that has already been disposed and to be able to define the positional relationship between the wiring and the magnetic thin film regardless of the position at which the power meter is attached to the wiring. Provided is an electrical power measurement device characterized by comprising the following: a sensor part that is connected to a circuit to be measured via a pair of connection terminals, and that is provided with the pair of connection terminals for connecting to a power source in parallel with a load, a magnetic element provided with element terminals on either end of a magnetic film, a measurement resistor connected in series to the magnetic element, and a detection means that detects voltage changes in the magnetic element and outputs a prescribed component; a sensor unit comprising a plurality of the sensor parts; an addition means that adds the outputs of the detection means of all of the sensor parts; and a securing means that secures the magnetic elements of the sensor parts in positions at equal distances from a virtual axis, which serves as a positional reference for disposing one electric wiring, in orientations facing the virtual axis.
Provided are: a method for treatment of an organic halogen compound, said method necessitating neither a large-scale treatment device nor a high operation cost and enabling efficient decomposition treatment of the organic halogen compound; and a catalyst which is to be used in the method. In this method, the decomposition treatment of an organic halogen compound is conducted by heating the organic halogen compound to 100 to 200ºC in the presence of both a catalyst comprising a copper oxide and hydrogen peroxide and thereby decomposing the compound through hydrothermal oxidation according to the Fenton method.
Heat medium transport paths (110, 120) are arranged between a first building (102) and a second building (101) and transport a heat medium that carries heat energy. A temperature distribution acquisition means acquires the temperature distribution for heat mediums that have different temperatures in the heat medium transport paths (110, 120) and are sequentially transported in the transport direction in the heat medium transport paths in a state wherein the heat mediums have a prescribed length. A control means (5) receives a load request for an air conditioner in the first building (102), and when a heat medium having heat energy capable of satisfying the received load request arrives at the first building (102), the control means causes heat energy to be extracted to the air conditioner in the first building (102) from the heat medium that has arrived, on the basis of the temperature distribution acquired by the temperature distribution acquisition means.
An easily dismantlable adhesive composition is provided containing: an acrylic polymer; and either an acid catalyst or an acid generator, the acrylic polymer containing: as monomer components, a carboxyl-precursor-group-containing-(meth)acrylate monomer; an n-butyl acrylate; and a polar-group-containing monomer, the content of the polar-group-containing monomer being 5 to 30% by mass, relative to the total mass of the monomer components composing the acrylic polymer, makes it possible to realize favorable adhesion- and dismantling properties and favorable delamination at an interface between an adherend and a substrate or an interface between an adhesive agent layer and an adherend when dismantled.
C09J 133/14 - Homopolymers or copolymers of esters of esters containing halogen, nitrogen, sulfur or oxygen atoms in addition to the carboxy oxygen
C09J 133/04 - Homopolymers or copolymers of esters
C08F 293/00 - Macromolecular compounds obtained by polymerisation on to a macromolecule having groups capable of inducing the formation of new polymer chains bound exclusively at one or both ends of the starting macromolecule
C09J 7/00 - Adhesives in the form of films or foils
C09J 133/12 - Homopolymers or copolymers of methyl methacrylate
C09J 153/00 - Adhesives based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Adhesives based on derivatives of such polymers
C09J 133/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
The ability to reduce the size of an electrical leakage detection device that uses a ring-shaped magnetic body is limited, and the size of the ring-shaped magnetic body is increased when electric wires are thick. It is also not easy to arrange a ring-shaped magnetic body with respect to electric wires that are already arranged. The present invention provides an electrical leakage detection device installed on a pair of power source lines for connecting a power source and a load, and is characterized by having a pair of retention means for retaining each of the pair of power source lines, a fixing means for fixing the pair of retention means at a predetermined interval from each other, a pair of magnetic elements disposed parallel to the power source lines in the retention means, a detecting means for detecting a difference in magneto-resistance effect between the pair of magnetic elements, and a driving means for channeling a drive current to the magnetic elements.
G01R 31/02 - Testing of electric apparatus, lines, or components for short-circuits, discontinuities, leakage, or incorrect line connection
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
H01H 83/02 - Protective switches, e.g. circuit-breaking switches, or protective relays operated by abnormal electrical conditions otherwise than solely by excess current operated by earth fault currents
74.
THERAPEUTIC AGENT OR PROPHYLACTIC AGENT FOR DEMENTIA
The invention provides a novel therapeutic agent or prophylactic agent for cognitive disorders. [SOLUTION MEANS] The invention provides an antibody that participates in antigen-antibody reaction specifically with tau protein that has been phosphorylated in the vicinity of Ser413 of SEQ ID NO: 1, and a therapeutic agent or prophylactic agent for cognitive disorders comprising as an active ingredient a peptide that has been phosphorylated in the vicinity of Ser413.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
C12N 15/02 - Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
The present invention provides a novel therapeutic agent or prophylactic agent for dementia. The present invention provides a therapeutic agent, prophylactic agent, or the like for dementia that contains a substance such as the following as an active ingredient: antibodies that specifically exhibit an antigen-antibody reaction to tau proteins of which the area around Ser413 of SEQ ID NO: 1 is phosphorylated; and peptides of which the area around Ser413 is phosphorylated.
A61K 39/395 - Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A61P 25/28 - Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
C07K 16/18 - Immunoglobulins, e.g. monoclonal or polyclonal antibodies against material from animals or humans
C12N 15/02 - Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
There has been a need for smaller-scale power factor measurement devices able to measure the power factor with a single element. This power factor measurement device is characterized by comprising: a pair of connecting ends (12) for connecting to a power source in parallel with a load; two magnetic elements (21, 22) by which identical external magnetic fields cause different changes in electric resistance; a pair of measurement terminals (13) for outputting a differential voltage of the two magnetic elements; a power factor sensor unit (10) comprising a pair of sensor terminals (10t) connected to the pair of connecting ends (12); a voltage detection unit (15) for measuring the voltage between the measurement terminals (13); a low-pass filter (16) connected to the output of the voltage detection unit (15); a high-pass filter (17) connected to the output of the voltage detection unit (15); a rectifier (18) connected to the high-pass filter (17); and a dividing means (19) for dividing the output of the low-pass filter (16) and the output of the rectifier (18).
The main purpose of the present invention is to provide: composite particles which can hold transplanted cells thereon satisfactorily for a period of time until the effect of the cells is developed; and a cell preparation comprising the composite particles and cells supported on the composite particles. The purpose can be achieved by composite particles each of which comprises inorganic particles adsorbed on the surface of a particle comprising an L-lactide-ε-caprolactone copolymer, wherein the constitutional molar ratio of L-lactide to an ε-caprolactone copolymer in the copolymer is approximately 75/25. The present invention also provides a cell preparation comprising cell-supported composite particles, which comprises cell-supported composite particles produced by supporting cells on the above-mentioned composite particles.
A61K 47/34 - Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
A61L 27/00 - Materials for prostheses or for coating prostheses
A61P 9/00 - Drugs for disorders of the cardiovascular system
A61P 43/00 - Drugs for specific purposes, not provided for in groups
The present invention pertains to: a mucin 5AC specific human antibody in which a heavy chain complementarity determining region 1 comprises an amino acid sequence represented by SEQ ID NO:1, a heavy chain complementarity determining region 2 comprises an amino acid sequence represented by SEQ ID NO:2, a heavy chain complementarity determining region 3 comprises an amino acid sequence represented by SEQ ID NO:3, a light chain complementarity determining region 1 comprising an amino acid sequence represented by SEQ ID NO:4, a light chain complementarity determining region 2 comprising an amino acid sequence represented by SEQ ID NO:5, and a light chain complementarity determining region 3 comprising an amino acid sequence represented by SEQ ID NO:6; an antigen-binding fragment of the mucin 5AC specific human antibody; and a pharmaceutical composition for the treatment of diseases involving the abnormal expression of mucin 5AC, said pharmaceutical composition containing the mucin 5AC specific human antibody and/or the antigen-binding fragment.
The present invention pertains to: a mucin 5AC specific human antibody in which the framework region has specific sequential characteristics; an antigen-binding fragment of the mucin 5AC specific human antibody; and a pharmaceutical composition for the treatment of diseases involving the abnormal expression of mucin 5AC, said pharmaceutical composition containing the mucin 5AC specific human antibody and/or the antigen-binding fragment.
A power measuring apparatus should be compact, and capable of measuring, in a single element, the categories of active power, reactive power, power factor and apparent power. The present invention has: a pair of connecting ends for connection to a power supply in parallel with a load; a sensor element having a pair of sensor terminals disposed on both ends of a magnetic film portion, one end of the sensor terminal being connected to one of the connecting ends, the sensor element being arranged adjacent to a connecting wire such that the longitudinal direction of the magnetic film portion is substantially parallel to the direction of flow of electric current in the connecting wire; n band pass filters connected in parallel to another end of the sensor terminals of the sensor element; a phase regulator connected in series to each of the band pass filters; a selection switch for selectively connecting the phase regulator; a measurement resistor having one end connected to the selection switch and the other end connected to the other connecting end; and a voltage detection unit, the measurement terminals of which being the respective sensor terminals, the voltage detection unit measuring the voltage between those measured terminals.
G01R 21/08 - Arrangements for measuring electric power or power factor by using galvanomagnetic-effect devices, e.g. Hall-effect devices
G01R 15/20 - Adaptations providing voltage or current isolation, e.g. for high-voltage or high-current networks using galvano-magnetic devices, e.g. Hall-effect devices
G01R 21/00 - Arrangements for measuring electric power or power factor
An object of the present invention is to provide a medicament and method for treating lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent comprising a compound represented by the general formula (I):
1 is lower alkyl substituted with lower alkoxy, lower alkyl substituted with a heterocyclic group, a heterocyclic group, or a group represented by the formula (IIa):
3 is lower alkyl optionally substituted with halogen, lower alkoxy, or phenyl; condensed polycyclic hydrocarbon; or hydrogen.
C07K 5/062 - Dipeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
C07K 5/083 - Tripeptides the side chain of the first amino acid being acyclic, e.g. Gly, Ala
A61K 31/27 - Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, e.g. meprobamate, carbachol, neostigmine
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
The present invention provides a charge/discharge measuring apparatus, which is capable of performing suitable charge/discharge management by accurately measuring a capacitance change of a secondary battery at the time of charging and discharging the secondary battery. This charge/discharge measuring apparatus is configured such that a current from a secondary battery can be switched to flow in a first connecting circuit, which connects in series the secondary battery, a load resistor, and a conductor film, or a second connecting circuit, which connects in series the secondary battery, a charger, and the conductor film. Furthermore the charge/discharge measuring apparatus has a voltage detecting means, which is disposed parallel to the conductor film, has a magnetic film connected in parallel to the connection to the load resistor and the charger from the secondary battery, and detects a voltage change in the magnetic film.
G01R 31/36 - Arrangements for testing, measuring or monitoring the electrical condition of accumulators or electric batteries, e.g. capacity or state of charge [SoC]
H01M 10/48 - Accumulators combined with arrangements for measuring, testing or indicating the condition of cells, e.g. the level or density of the electrolyte
83.
NUCLEIC ACID MOLECULE FOR INHIBITING ACTIVITY OF RNAI MOLECULE
The purpose of the present invention is to develop and provide a nucleic acid molecule which can inhibit the activity of an target RNAi molecule specifically and with high efficiency and can be produced safely at low cost. Provided is a nucleic acid molecule for inhibiting the activity of a target RNAi molecule, comprising: a single-stranded nucleic acid moiety which contains one un-modified DNA region comprising a nucleotide sequence completely or satisfactorily complementary to a nucleotide sequence for a functional chain that is contained in the target RNAi molecule and has the activity; and a double-stranded nucleic acid moiety which is connected to the 5'-terminal and/or the 3'-terminal of the single-stranded nucleic acid moiety.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
A61K 31/713 - Double-stranded nucleic acids or oligonucleotides
Provided are an improved double-stranded nucleic acid molecule for gene expression control mediated by gene silencing; a method for producing the same; and a pharmaceutical composition comprising the double-stranded nucleic acid molecule. Provided are a double-stranded nucleic acid molecule for gene expression control, which comprises an antisense chain having the length of 18 to 28 bases and a sense chain including a complementary portion formed from a sequence that is sufficiently complementary to the antisense chain, and at the 5' terminal, a single-stranded projecting portion having the length of 2 to 100 bases, wherein the sense chain and the antisense chain form a base bond via the complementary portion; a method for producing the same; and a pharmaceutical composition containing the double-stranded nucleic acid component as the active ingredient.
C12N 15/113 - Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides
A61K 31/7105 - Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
A61K 48/00 - Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
[Problem] To provide a stereoscopic endoscope that can be inserted in a nostril and is easy to manipulate. [Solution] This stereoscopic endoscope is provided with: a first inserted member that is formed in a rod shape; a second inserted member that is formed in a rod shape; a first optical system in which an objective lens is provided on one end of the first inserted member; a second optical system in which an objective lens is provided on one end of the second inserted member; and a connecting means for detachably connecting the one ends of the first and second inserted members to each other.
A61B 1/00 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
A61B 1/233 - Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the nose, i.e. nasoscopes
The present invention provides a rare metal-free active material able to obtain a secondary battery with high capacity and excellent cycle characteristics, and a secondary battery using this active material. The present invention is a cathode active material containing an organic compound having a skeleton of graphene fragments or a derivative thereof.
In order to remove bad-breath and prevent fillings from blackening it is primarily necessary to remove VSCs. Therefore, it is necessary to adsorb the VSCs generated in the mouth, in other words, a liquid-phase material having high VSCs adsorbing properties is required. A hydrotalcite represented by the composition Mg1-xAlx(OH)2An-x/n・nH2O (An-: anion) is heat treated at 500℃, and particles which have changed a layered structure from the state immediately following synthesis are in a liquid phase and have extremely high VSCs adsorbing properties, thus can be effective in removing bad-breath.
The present invention addresses the problem of providing: a non-fluid functional hydrogel which is formed from keratin; and a method for producing the functional hydrogel. The problem can be solved by a method for producing a functional hydrogel, which comprises the steps described below, and a functional hydrogel which is produced by the production method. (1) A step wherein a reducing agent for converting a disulfide bond to a thiol group is added to a keratin-containing material, so that keratin is extracted. (2) A step wherein a protein stabilizer for preventing a thiol group from re-forming a disulfide bond is added to the keratin-containing material. (3) A step wherein the keratin is purified by removing the protein stabilizer, thereby obtaining a keratin solution. (4) A step wherein a functional hydrogel is produced by concentrating the keratin solution.
The present invention provides a highly dismantlable adhesive composition which comprises (X) an acrylic polymer containing a (meth)acrylate monomer as the main monomer component and either an acid catalyst or an acid generator, and which is characterized in that the acrylic polymer (X) contains (A) a poly(meth)acrylate chain that comprises repeating units each derived from (a) a (meth)acrylate monomer containing a carboxyl precursor group, wherein the number of the repeating units in the poly(meth)acrylate chain (A) is 10 or more.
C09J 133/06 - Homopolymers or copolymers of esters of esters containing only carbon, hydrogen and oxygen, the oxygen atom being present only as part of the carboxyl radical
C09J 153/00 - Adhesives based on block copolymers containing at least one sequence of a polymer obtained by reactions only involving carbon-to-carbon unsaturated bonds; Adhesives based on derivatives of such polymers
90.
SEMICONDUCTOR PARTICLE AND METHOD OF MANUFACTURE THEREOF
A method of manufacturing semiconductor particles includes: preparing a cation mixture by mixing together a copper ion source, a zinc ion source, a tin ion source, a ligand which suppresses bonding reactions between ions, and water (S I); preparing a precursor solution by mixing the prepared cation mixture with a sulfur ion source (S2); placing the prepared precursor solution in a vessel and sealing the vessel containing the precursor solution (S3); and generating a hydrothermal synthesis reaction in the sealed vessel (S4). The semiconductor particles include copper, zinc, tin and sulfur, are observed in X-ray diffraction analysis to have single-phase peaks, and have a particle size equal to or lower than 100 nm.
It is possible to achieve favorable adhesion and dismantling characteristics and it is possible to also suppress stick-slipping during dismantling by means of this easily dismantled adhesive agent composition, which contains an acid catalyst or an acid generator, and an acrylic block polymer having: a poly(meth)acrylate chain (A) comprising a carboxyl-precursor-group-containing (meth)acrylate monomer (a); and a poly(meth)acrylate chain (B) containing as monomer components a (meth)acrylate (b) having an alkyl group having 1-14 carbon atoms, and a polar-group-containing monomer (c).
It is possible to achieve favorable adhesion and dismantling characteristics and it is possible to favorably delaminate an adherend/substrate interface or an adhesive agent layer/adherend interface during dismantling by means of this easily dismantled adhesive agent composition, which contains an acid catalyst or an acid generator, and an acrylic polymer that contains a carboxyl-precursor-group-containing (meth)acrylate monomer, an n-butyl acrylate, and a polar-group-containing monomer as monomer components, and that has an amount of polar-group-containing monomer that is 5-30 mass% of the monomer components forming the acrylic polymer.
It is possible to achieve favorable adhesion and dismantling characteristics and it is possible to favorably delaminate an adherend/substrate interface or an adhesive agent layer/adherend interface during dismantling by means of this easily dismantled adhesive agent composition, which contains an acid catalyst or an acid generator, and an acrylic polymer containing as monomer components a carboxyl-precursor-group-containing (meth)acrylate monomer, 2-ethylhexylacrylate, and a polar-group-containing monomer.
This invention aims to easily provide a composition capable of increasing the activity of dehydrogenase. This composition is characterized by having an extract derived from yerba mate as an active component and by increasing the activity of dehydrogenase. Further, in a preferred embodiment of this composition for increasing the activity of dehydrogenase, the dehydrogenase is characterized by being an alcohol dehydrogenase. This composition for liver disease is characterized by having an extract derived from yerba mate as an active component. Further, a preferred embodiment of this composition for liver disease is characterized by said liver disease being an alcoholic liver disease.
A61K 36/00 - Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
A61P 1/16 - Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
[Problem] To discover a peptide useful for immunotherapy of liver cancer, and to provide an effective treatment method and early diagnosis method. [Solution] A peptide comprising an amino acid sequence of any of (1)-(6) below and having immunity-inducing activity. AYPMPFITTI (1) AYCETHYNQL (2) FLVQSSDFKV (3) ILFVQYFHRV (4) KLTLKNKFV (5) ELYHEQCFV (6)
[Problem] To provide a method for treating an organic chlorine compound, as well as a catalyst used in the method of treatment, whereby the organic chlorine compound can be efficiently degraded and treated without the need for a large-scale treatment device nor for major operating costs. [Solution] An organic chlorine compound is heated to 50-400°C in the presence of a metal oxide doped with at least one element selected from the group consisting of manganese, iron, cobalt, nickel, and copper, to carry out a hydrothermal oxidation reaction. The hydrothermal reaction is carried out under irradiation with light of a wavelength of at least 300 nm.
A62D 3/38 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by reacting with chemical agents by combustion
A62D 3/20 - Processes for making harmful chemical substances harmless, or less harmful, by effecting a chemical change in the substances by hydropyrolysis or destructive steam gasification, e.g. using water and heat to effect chemical change
The present invention provides power measuring apparatuses of various thin film sensor types, which can easily measure, with a small configuration, power in high frequency circuits and batteries. This power measuring apparatus is provided with: a magnetic film, which is disposed in parallel to a primary conductor having a load current flowing therein; a power feed unit, which is provided with an input/output terminal that supplies an element current to the magnetic film; a bias magnetic field applying unit, which applies a direct current magnetic field that is parallel or perpendicular or diagonal to the magnetization direction of the magnetic film; and a detecting unit, which detects a voltage between the edge portions of the magnetic film in the element current direction. The power measuring apparatus detects merely a direct current voltage composition between the edge portions of the magnetic film in the element current direction.
The present invention addresses the problem of providing a drug and method for the treatment of lissencephaly patients. The present invention provides a lissencephaly therapeutic or preventive agent containing a compound represented by general formula (I) (where R1 is a lower alkyl group substituted by a lower alkoxy group, a lower alkyl group substituted by a heterocyclic group, a heterocyclic group, or a group represented by formula (IIa) (where R4 is a lower alkyl group, R5 is a lower alkylene group, and m is an integer between 1 and 6); R2 is a lower alkyl group optionally substituted by a phenyl group; and R3 is a lower alkyl group (optionally substituted by a halogen, lower alkoxy group, or phenyl group), a condensed polycyclic hydrocarbon group, or a hydrogen atom).
A61K 31/27 - Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, e.g. meprobamate, carbachol, neostigmine
A61K 31/341 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
A61K 31/351 - Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
A61P 25/00 - Drugs for disorders of the nervous system
C07K 5/023 - Peptides having up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link in which at least a beta-amino acid is involved
The ratio of measurement values of glucose, citric acid, and cis-aconitic acid in a biological sample of a subject to the measurement values of healthy subjects is calculated, and the glucose ratio, citric acid ratio, and cis-aconitic acid ratio are used to assess and/or determine fatigue. In the same way, the isocitric acid ratio, succinic acid ratio, malic acid ratio, and lactic acid ratio are calculated, combined with the three abovementioned ratios, and used to assess and/or determine fatigue. Thus enabled is the objective and simple diagnosis and assessment of fatigue.
OSAKA PREFECTURE UNIVERSITY PUBLIC CORPORATION (Japan)
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION (Japan)
NATIONAL UNIVERSITY CORPORATION NARA INSTITUTE OF SCIENCE AND TECHNOLOGY (Japan)
Inventor
Suzuki, Toshio
Ueda, Hideaki
Nagasaki, Takeshi
Kirihata, Mitsunori
Numata, Munenori
Ikeda, Atsushi
Abstract
Provided is a complex of a hydrophobic cluster compound and a β-1,3-1,6-D-glucan for which the branching degree of β-1,6 bonds is between 50% and 100% that of β-1,3 bonds.
patents
