2022
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Invention
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Pharmaceutical salts of a chk-1 inhibitor. The invention provides a pharmaceutically acceptable s... |
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Invention
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Preparation of a chk1 inhibitor compound. The invention provides a novel synthetic route for the ... |
2021
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Invention
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Pyrrole derivatives as plk1 inhibitors. The invention provides compounds of the formula (3):
4.
... |
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Invention
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A pharmaceutical salt of an arylpyrrole derivative.
The present invention relates to (R)-4-[5-(4... |
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Invention
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A pharmaceutical salt of an arylpyrrole derivative. The present invention relates to (/?)-4-[5-(4... |
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Invention
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Pharmaceutical compounds. This invention relates to compounds that inhibit or modulate the activi... |
2020
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Invention
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Pyrrolo[2,3-d]pyrimidine derivatives and their use in the treatment of cancer. The invention prov... |
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Invention
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Pharmaceutical compounds.
The invention provides a composition of matter which:
The invention ... |
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Invention
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Pharmaceutical compounds. The invention provides a composition of matter which: ? (i) consists of... |
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Invention
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Pharmaceutical compounds. The invention provides a composition of matter which: • (i) consists of... |
2019
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Invention
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2-aminoquinazoline derivatives as p70s6 kinase inhibitors. The invention provides compound that i... |
2018
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Invention
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Pyrrole derivatives as plk1 inhibitors. The invention provides compounds of the formula (3): or a... |
2017
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Invention
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Pharmaceutically active pyrazine derivatives.
The invention provides compounds which inhibit or ... |
2016
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Invention
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Substituted quinoxalines and benzotriazine p70s6 kinase inhibitors. The invention provides compou... |
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Invention
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Modulators of the p70s6 kinase for use in the treatment of brain disorders and triple-negative br... |
2015
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Invention
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Pyrazole compounds as chk1 inhibitors for the treatment of cancer. This invention relates to pyra... |
2012
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Invention
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Pharmaceutically active pyrazine derivatives. The invention provides compounds which inhibit or m... |
2011
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Invention
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Pharmaceutical compounds. A compound of the formula (I):
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Invention
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Modulators of chk-1 activity. The invention provides a compound of the formula (1): or a salt, N-... |
2010
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Invention
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Substituted benzotriazines and quinoxalines as inhibitors of p7os6 kinase. The invention provides... |
2009
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Invention
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Pharmaceutical compounds. The invention provides kinase inhibitor compounds of the formula (1):
... |
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Invention
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Pharmaceutical compounds. The invention provides kinase inhibitor compounds of the formula (1): o... |
2008
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Invention
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N-oxide-containing pharmaceutical compounds. The invention provides a method of preparing a thera... |
2007
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Invention
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Anticancer compounds with a benzo ( 1, 2, 4 ) triazin-3yl-amine core. The invention provides comp... |
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Invention
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Quinoline and quinoxaline n-oxides as chk-1 inhibitors. The invention provides compounds of the f... |
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Invention
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Pharmaceutical compounds. The invention provides a compound of the formula (1) or a salt, solvate... |
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Invention
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N-oxides of diarylurea derivatives and their use as chk1 inhibitors for the treatment of cancer. ... |
2006
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Invention
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Heterocyclic n-oxides as hypoxic selective protein kinase inhibitors.
The invention relates to n... |
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Invention
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Heterocyclic triazines as hypoxic selective protein kinase inhibitors. The invention relates to n... |
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Invention
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Heterocyclic n-oxides as hypoxic selective protein kinase inhibitors. The invention relates to no... |