The United States of America, as represented by the Secretary, Department of Health and Human Serv

United States of America

 
Total IP 38
Total IP Rank # 37,024
IP Activity Score 2.4/5.0    37
IP Activity Rank # 20,391

Patents

Trademarks

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Last Patent 2025 - Nuclear magnetic resonance metho...
First Patent 2008 - Methods for treatment of degener...

Latest Inventions, Goods, Services

2024 Invention Ultrasound-sensitive peptide particles for spatially resolved molecule delivery. The present inv...
Invention Compounds for treating or preventing alzheimer's disease. A subject is administered an amount of...
Invention Remodilins to prevent or treat cancer metastasis, glaucoma, and hypoxia. Disclosed herein is a c...
Invention Virus-like particle conjugates for diagnosis and treatment of tumors. The present disclosure is ...
2023 Invention Methods for producing autologous t cells useful to treat b cell malignancies and other cancers an...
Invention Heptamethine cyanines for use as fluorescent markers of the biliary and renal systems. Heptameth...
Invention Self-assembling nanoparticles. The present disclosure relates to a vaccine comprising at least o...
Invention Methods of preparing t cells for t cell therapy. Provided herein are methods for delaying or inh...
Invention T cell receptors recognizing hla-cw8 restricted mutated kras. Disclosed is an isolated or purifi...
Invention Crystal forms and methods of synthesis of (2r, 6r)-hydroxynorketamine and (2s, 6s)-hydroxynorketa...
2022 Invention Suppression of uveitis by single domain antibody. The present invention provides methods of trea...
Invention Cannabinoid receptor modulating compounds. In accordance with the purpose(s) of the present disc...
Invention Hla-a3-restricted t cell receptors against ras with g12v mutation. Disclosed is an isolated or p...
Invention Nuclear magnetic resonance methods of determining homeostatic perturbations. Disclosed are metho...
Invention Augmentation of innate and adaptive immunity by inhibition of interaction of lilrbs with mhc-1. ...
Invention Treatments for diffuse large b-cell lymphoma. Disclosed are methods for treating specific geneti...
Invention Compositions and methods for determining responsiveness to immune checkpoint inhibitors (ici), in...
Invention Photosensitizing antibody-fluorophore conjugates. The present disclosure relates to compositions...
Invention T cell receptors recognizing c135y, r175h, or m237i mutation in p53. Disclosed are isolated or p...
Invention Fatty acid derivatives and their use. This disclosure concerns fatty acid derivatives, pharmaceu...
Invention Near infrared photoimmunotherapy (nir-pit) combination therapy to treat cancer. Provided herein ...
2021 Invention Virus-like particle conjugates for diagnosis and treatment of tumors. The present disclosure is d...
Invention Targeted cancer therapy. Some embodiments of the present disclosure are directed to methods that...
Invention Methods to produce very long chain fatty acids (vlcfa). The disclosure provides methods of synth...
Invention Multi-cyclic irak and flt3 inhibiting compounds and uses thereof. Some embodiments of the disclo...
Invention Neutralizing antibodies to gp120 and their use. Antibodies and antigen binding fragments that sp...
Invention Size-dependent brain and lymphatic distribution of macromolecular drug delivery platform. The pr...
Invention Live attenuated respiratory syncytial virus. Reported herein are novel recombinant respiratory s...
Invention Methods of preventing hiv infections in humans. A process is provided for protecting a primate h...
Invention Methods of inhibiting hiv infections by pre-exposure prophylaxis. A process is provided for prot...
Invention Sars-cov-2 vaccine. SARS-CoV-2 S ectodomain trimers stabilized in a prefusion conformation, nucl...
Invention Fentanyl haptens for the preparation of a fentanyl vaccine. Described is the preparation of nove...
2020 Invention Tnap locally administered for promoting periodontal health. Methods are disclosed for treating p...
Invention Pre-exposure prophylaxis of hiv infections. A process is provided for protecting a primate host ...
Invention Hiv pre-exposure prophylaxis. Disclosed is the use of a nucleoside reverse transcriptase inhibit...
2019 Invention Combination of near infrared photoimmunotherapy targeting cancer cells and host-immune activation...
Invention Plasmodial surface anion channel inhibitors for the treatment or prevention of malaria. 2 are as ...
Invention Diagnostic method for pediatric acute-onset neuropsychiatric syndrome (pans) and pediatric autoim...
2018 Invention Iodonium analogs as inhibitors of nadph oxidases and other flavin dehydrogenases; formulations th...
Invention Polydopamine-encapsulated nanodiamonds and methods. A method of preparing a polydopamine-coated ...
Invention Nasal dry powder delivery system for vaccines and other treatment agents. A nasal delivery devic...
Invention Methanocarba derivatives of pseudoribose that inhibit adenosine kinase. Adenosine kinase inhibit...
Invention Denoising of dynamic magnetic resonance spectroscopic imaging using low rank approximations in th...
2017 Invention Methods of making 18f-labeled precursors and peptides, labeled c-met binding peptides, and method...
Invention Inhibitor of heme degradation for use to improve antibiotic treatment of mycobacterium tuberculos...
Invention Tissue characterization with acoustic wave tomosynthesis. Imaging of internal structure of a pat...
Invention Albumin-binding immunomodulatory compositions and methods of use thereof. The present disclosure...
Invention Methods of using (2r, 6r)-hydroxynorketamine and (2s, 6s)-hydroxynorketamine in the treatment of ...
2016 Invention Method for reproducible differentiation of clinical-grade retinal pigment epithelium cells. Prov...
Invention Organotrifluoroborate mimics of amino acids and uses thereof. Disclosed are boron mimics of amin...