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2012
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Invention
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Novel rapamycin analogue. There is provided inter alia a compound of formula (I) or a pharmaceuti... |
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2011
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Invention
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Amine or amid analogues of sanglifehrin. The present invention relates to macrocyclic sanglifehri... |
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Invention
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Sanglifehrin based compounds. There are provided inter alia compounds of formula (I) for use as c... |
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Invention
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Sanglifehrin based compounds. There are provided inter aliacompounds of formula (I) for use as cy... |
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Invention
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Sanglifehrin based compounds. There are provided inter alia compounds of formula (I) useful as cy... |
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2010
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Invention
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Novel macrocyles and methods for their production. There are provided compounds of formula (I) or... |
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Invention
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Novel macrocycles and methods for their production. There are provided compounds of formula (I) o... |
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Invention
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Polyketides analogues and methods for their production. The invention relates to compounds of for... |
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Invention
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Fk506 and fk520 analogues and their pharmaceutical uses. The present invention relates to novel F... |
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2009
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Invention
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39-desmethoxy derivatives of rapamycin. The present invention relates to 39-desmethoxyrapamycin d... |
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Invention
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Novel compounds and methods for their production. Compounds of formula (I) their use as medicamen... |
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2008
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Invention
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36-des(3-methoxy-4-hydroxycyclohexyl) 36-(3-hydroxycycloheptyl) derivatives of rapamycin for the ... |
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Invention
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39-desmethoxy-39-methyl derivatives of rapamycin. The present invention relates to novel 39-desme... |
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Invention
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Methods of screening for anti-angiogenic compounds.
The present invention relates to methods of ... |
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Invention
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Methods of screening for anti-angiogenic compounds. The present invention relates to methods of s... |
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Invention
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C21-de0xy ansamycin derivatives as antitumor agents. According to the invention there are provide... |
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2007
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Invention
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Novel compounds and methods for their production. The present invention relates to ansamycin anal... |
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Invention
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18, 21-didesoxymacbecin derivatives for the treatment of cancer. The present invention relates to... |
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Invention
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Production of polyketides and other natural products. The present invention relates to production... |
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Invention
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36 -des (3 -methoxy-4 -hydroxycyclohexyl) 36 - (3 -hydroxycycloheptyl) derivatives of rapamycin f... |
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Invention
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39-desmethoxy-39-methyl derivatives of rapamycin.. The present invention relates to novel 39-desm... |
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Invention
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Novel compounds.
The present invention relates to derivatives of borrelidin that are useful in m... |
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Invention
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Borrelidin derivatives as antiproliferative agents and angiogenesis inhibitors. The present inven... |
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Invention
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17-oxymacbecin derivatives and their use in the treatment of cancer and/or b-cell malignancies.
... |
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Invention
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18 ,21-didesoxymacbecin derivatives for the treatment of cancer.
The present invention relates t... |
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Invention
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17-oxymacbecin derivatives and their use in the treatment of cancer and/or b-cell malignancies. T... |
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Invention
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18,21-didesoxymacbecin derivatives for the treatment of cancer. The present invention relates to ... |
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Invention
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4,5-dihydromacbecin derivatives and their use in the treatment of cancer or b-cell malignancies. ... |
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Invention
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Novel compounds and methods for their production.
The present invention relates to 15-desmethoxy... |
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Invention
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15-o-desmethylmacbecin derivatives and their use in the treatment of cancer or b-cell malignancie... |
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Invention
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Novel compounds and methods for their production.
The present invention relates to 11-O-desmethy... |
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Invention
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4, 5-dihydromacbecin derivatives and their use in the treatment of cancer or b-cell malignancies.... |
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Invention
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15-desmethoxymacbecin derivatives for the treatment of cancer diseases. The present invention rel... |
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Invention
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Novel compounds and methods for their production. The present invention relates to 11-O-desmethyl... |
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Invention
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39-desmethoxyrapamycin, compositions and methods of use thereof. The present invention relates to... |
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2006
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Invention
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21-deoxymacbecin analogues useful as antitumor agents. The present invention relates to 21-deoxym... |
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Invention
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Hybrid glycosylated products and their production and use. The present invention relates to hybri... |
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Invention
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Novel ansamycin derivatives. There are provided inter alia derivatives of a benzenoid ansamycin w... |
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Invention
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Medical uses of 39-desmethoxyrapamycin and analogues thereof.
The present invention relates to m... |
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Invention
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39-desmethoxy derivatives of rapamycin. The present invention relates to novel 39-desmethoxyrapam... |
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Invention
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Medical uses of 39-desmethoxyrapamycin and analogues thereof. The present invention relates to me... |
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Invention
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Polyketides and their synthesis and use. The rapamycin gene cluster is an example of a gene clust... |
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2004
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Invention
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Polyketides and their synthesis.
Macrolides particularly erythromycins and azithromycins, having... |
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Invention
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Erythromycins and process for their preparation. Streptomyces eurythermus DSM 40014) or produced ... |
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2003
|
Invention
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Borrelidin-producing polyketide synthase and its use. The present invention relates to the biosyn... |
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2002
|
Invention
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Hybrid glycosylated products and their production and use.
Hybrid glycosylated products such as ... |
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2001
|
Invention
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Hybrid polyketide synthases and novel loading domains. A polyketide synthase (“PKS”) of Type I is... |
