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2025
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Invention
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Myosin 15 promoters and uses thereof.
The disclosure provides polynucleotides containing regions... |
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2024
|
Invention
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Compositions and methods for treating sensorineural hearing loss using otoferlin dual vector syst... |
|
|
Invention
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Compositions and methods for treating gjb2-related hearing loss. The disclosure provides polynucl... |
|
|
Invention
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Methods for treating sensorineural hearing loss using otoferlin dual vector systems. The disclosu... |
|
|
Invention
|
Modified rep-cap plasmids and uses thereof.
The disclosure provides modified rep-cap plasmids co... |
|
|
Invention
|
Modified rep-cap plasmids and uses thereof. The disclosure provides modified rep-cap plasmids con... |
|
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Invention
|
Methods and compositions for administering otoferlin dual vector systems.
The disclosure feature... |
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|
Invention
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Methods and compositions for administering otoferlin dual vector systems. The disclosure features... |
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2023
|
Invention
|
Hypertonic pharmaceutical compositions containing an anti-platinum chemoprotectant agent.
Hypert... |
|
|
Invention
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Slc26a4 regulatory elements and uses thereof. The disclosure provides SL26A4 promoters and SLC26A... |
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|
Invention
|
Methods and compositions for generating type i vestibular hair cells. The disclosure provides Tbx... |
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|
Invention
|
Slc26a4 regulatory elements and uses thereof. The disclosure provides SL26A4 enhancers and SLC26A... |
|
|
Invention
|
Methods of otoprotection against platinum-based antineoplastic agents.
Disclosed herein are meth... |
|
|
Invention
|
Gjb2 regulatory elements and uses thereof.
The disclosure provides gap junction protein beta 2 (... |
|
|
Invention
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Gjb2 regulatory elements and uses thereof. The disclosure provides gap junction protein beta 2 (G... |
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2022
|
Invention
|
Stereocilin promoters and uses thereof.
The disclosure provides stereocilin (STRC) promoters, as... |
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|
Invention
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Stereocilin promoters and uses thereof. The disclosure provides stereocilin (STRC) promoters, as ... |
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|
Invention
|
Compositions and methods for cell type-specific gene expression in the inner ear.
The disclosure... |
|
|
Invention
|
Compositions and methods for cell type-specific gene expression in the inner ear. The disclosure ... |
|
|
Invention
|
Compositions and methods for treating sensorineural hearing loss using stereocilin dual vector sy... |
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|
Invention
|
Vestibular supporting cell promoters and uses thereof.
The disclosure provides polynucleotides c... |
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|
Invention
|
Vestibular supporting cell promoters and uses thereof. The disclosure provides polynucleotides co... |
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|
Invention
|
Cochlear outer hair cell promoters and uses thereof.
The disclosure provides polynucleotides con... |
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|
Invention
|
Cochlear inner hair cell promoters and uses thereof.
The disclosure provides polynucleotides con... |
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|
Invention
|
Methods and compositions for reducing nucleic acid vector-induced toxicity in the inner ear.
The... |
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|
Invention
|
Methods and compositions for reducing nucleic acid vector-induced toxicity in the inner ear. The ... |
|
|
Invention
|
Methods for treating sensorineural hearing loss using otoferlin dual vector systems.
The disclos... |
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2021
|
Invention
|
Crispr sam biosensor cell lines and methods of use thereof.
Disclosed are cell lines that stably... |
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|
Invention
|
Myosin 15 promoters and uses thereof. The disclosure provides polynucleotides containing regions ... |
|
|
Invention
|
Hypertonic pharmaceutical compositions containing an anti-platinum chemoprotectant agent. Hyperto... |
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|
G/S
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Genetic testing for medical purposes for the testing of hearing loss and balance disorders; none ... |
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|
G/S
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Genetic testing for medical purposes. |
|
|
Invention
|
Compositions and methods for promoting hair cell regeneration.
The disclosure provides nucleic a... |
|
|
Invention
|
Compositions and methods for promoting hair cell regeneration. e.ge.g., cochlear and/or vestibula... |
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|
Invention
|
Methods and compositions for generating type 1 vestibular hair cells.
The disclosure provides So... |
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|
Invention
|
Methods and compositions for generating type i vestibular hair cells. The disclosure provides Sox... |
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2020
|
Invention
|
Cochlear inner hair cell promoters and uses thereof. The disclosure provides polynucleotides cont... |
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|
Invention
|
Cochlear outer hair cell promoters and uses thereof. The disclosure provides polynucleotides cont... |
|
|
Invention
|
Glycerol as a permeation enhancer and compositions containing the same. The invention provides au... |
|
|
Invention
|
Permeation enhancers, compositions containing them, and methods of using the same. The invention ... |
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2019
|
Invention
|
Compositions and methods for the delivery of therapeutic agents across the round window membrane.... |
|
|
Invention
|
Aav1 vectors and uses thereof for treatment of otic indications.
The invention provides AAV1 vec... |
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G/S
|
Pharmaceutical preparations for the treatment of hearing, speech recognition, and balance disorde... |
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G/S
|
Pharmaceutical preparations for the treatment of hearing,
speech recognition, and balance disord... |
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G/S
|
pharmaceutical preparations for the treatment of hearing, speech recognition, and balance disorde... |
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2017
|
G/S
|
Pharmaceutical preparations for the treatment of hearing loss, speech recognition, and balance di... |
