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2024
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Invention
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Small molecule ligands and aptamers. The present disclosure provides small molecules of Formula (... |
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Invention
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Cation exchange chromatography for aav capture. The present disclosure provides methods for isola... |
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Invention
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Inflammation-inducible promoters. Provided herein are inflammation-inducible hybrid promoters. Fu... |
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2023
|
Invention
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Nucleic acid regulatory elements for gene expression in the muscle and methods of use. The applic... |
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Invention
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Chromatography methods for purification of aav capsids. The present disclosure provides methods f... |
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Invention
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Formulations for aav gene therapy. Compositions for the storing and maintaining virus viability i... |
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Invention
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Atp7b gene therapy. Provided herein are improved expression constructs for the expression of ATP7... |
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Invention
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Nucleic acid regulatory elements for constitutive gene expression and methods of use. The applica... |
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Invention
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Nucleic acid regulatory elements for gene expression in the liver and methods of use. The applica... |
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Invention
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Bdnf gene therapy. This disclosure provides BDNF expression constructs and vectors comprising suc... |
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Invention
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Upf1 expression constructs. Provided herein are improved expression constructs for the expression... |
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|
Invention
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Nucleic acid regulatory elements for gene expression in the central nervous system and methods of... |
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|
Invention
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Regulation of gene expression by aptamer-modulated rnase p cleavage.
The present disclosure prov... |
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Invention
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Regulation of gene expression through aptamer-modulated polyadenylation.
The invention provides ... |
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2022
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Invention
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Polycistronic expression of gut peptides. Provided herein are monocistronic, bicistronic, and pol... |
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Invention
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Aptamers and small molecule ligands. The present disclosure provides aptamers that bind to certai... |
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Invention
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Regulation of gene expression via aptamer-mediated control of self-cleaving ribozymes.
The inven... |
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Invention
|
Kcnv2 gene therapy.
Provided herein are expression constructs, viral genomes, and vectors for th... |
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Invention
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Kcnv2 gene therapy. Provided herein are expression constructs, viral genomes, and vectors for the... |
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Invention
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Retgc gene therapy. Provided herein are expression constructs, viral genomes, and vectors for the... |
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Invention
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Kcnv2 gene therapy. KCNV2KCNV2 gene, the method comprising administering to the subject a vector ... |
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|
Invention
|
High throughput cell-based screening for aptamers.
The invention provides eukaryotic cell-based ... |
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|
Invention
|
Aav manufacturing methods.
Methods for producing recombinant adeno-associated virus (rAAV) parti... |
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Invention
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Aav manufacturing methods. Methods for producing recombinant adeno-associated virus (rAAV) partic... |
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Invention
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Regulation of gene expression by aptamer-mediated modulation of alternative splicing.
The invent... |
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2021
|
Invention
|
Motorized injection system and methods of use.
System and methods for injection into a cavity ar... |
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Invention
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Motorized injection system and methods of use. System and methods for injection into a cavity are... |
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Invention
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Aptamers that bind thiamine analogs and derivatives.
The present disclosure relates to oligonucl... |
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Invention
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Aptamers that bind thiamine analogs and derivatives. The present disclosure relates to oligonucle... |
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2020
|
Invention
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Methods for treating parkinson's disease.
Disclosed are methods for treating neurological disord... |
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Invention
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Methods for treating parkinson's disease. Disclosed are methods for treating neurological disorde... |
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Invention
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Stabilization of retromer for the treatment of alzheimer's disease and other neurodegenerative di... |
|
|
Invention
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Injection systems and methods of their use.
An injection system comprising a syringe barrel; a f... |
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Invention
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Modified aav capsid proteins for treatment of arthritic disease.
The invention relates to recomb... |
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Invention
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Modified aav capsid proteins for treatment of arthritic disease. The invention relates to recombi... |
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2019
|
Invention
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Regulation of gene expression by aptamer-mediated modulation of alternative splicing. The inventi... |
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Invention
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Modified raav capsid protein for gene therapy.
The invention relates to recombinant adeno-associ... |
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2018
|
Invention
|
Regulation of gene expression by aptamer-modulated rnase p cleavage. The present disclosure provi... |
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2017
|
Invention
|
High throughput cell-based screening for aptamers. The invention provides eukaryotic cell-based s... |
|
|
Invention
|
Regulation of gene expression via aptamer-mediated control of self-cleaving ribozymes. The invent... |
|
|
Invention
|
Regulation of gene expression through aptamer-modulated polyadenylation. The invention provides p... |
