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2024
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Invention
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Kat6a as a predictive biomarker for treatment with a kat6a inhibitor and methods of treatment the... |
|
2023
|
Invention
|
Compounds.
A compound of formula (I), or a pharmaceutically acceptable salt thereof:
A compoun... |
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|
Invention
|
Dosing regimens comprising a kat6 inhibitor for the treatment of cancer. The invention relates to... |
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|
Invention
|
Substituted condensed thiophenes as modulators of sting.
A compound of formula (I):
A compound... |
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2022
|
Invention
|
Benzisoxazole sulfonamide derivatives.
The present invention relates to compounds of formula (I)... |
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2021
|
Invention
|
Compounds.
A compound of formula (I), or a pharmaceutical salt thereof:
A compound of formula ... |
|
|
Invention
|
Kat6 inhibitor methods and combinations for cancer treatment. This invention relates to methods a... |
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2020
|
Invention
|
Compounds.
This disclosure relates to compounds of formula (I), which are modulators of STING. A... |
|
|
Invention
|
Compounds. This disclosure relates to compounds of formula (I), which are modulators of STING. Al... |
|
|
Invention
|
Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting.
A c... |
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|
Invention
|
Benzothiophene, thienopyridine and thienopyrimidine derivatives for the modulation of sting. A co... |
|
|
Invention
|
Cycloalkyl and heterocycloalkyl benzisoxazole sulfonamide derivatives. The present invention rela... |
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|
Invention
|
Benzisoxazole sulfonamide derivatives. The present invention relates to compounds of formula (I) ... |
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2019
|
Invention
|
3-oxa-8-azabicyclo[3.2.1]octane derivatives and their use in the treatment of cancer and hemoglob... |
|
|
Invention
|
Compounds. A compound of formula (I), or a pharmaceutically acceptable salt thereof.
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|
|
Invention
|
Compounds. A compound of formula (I), or a pharmaceutically acceptable salt thereof. |
|
|
Invention
|
Compounds. A compound of formula (I), or a pharmaceutical salt thereof. |
|
|
Invention
|
Substituted condensed thiophenes as modulators of sting. Y is selected from: (RYA) and (RYB). |
|
|
Invention
|
Substituted condensed thiophenes as modulators of sting. A compound of formula (I), wherein: R1 i... |
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|
Invention
|
Substituted condensed thiophenes as modulators of sting. A compound of formula (I), wherein: R13-... |
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2018
|
Invention
|
Prmt5 inhibitors. The present invention provides a compound of Formula (I) or the pharmaceuticall... |
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|
Invention
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Fused [1,2,4]thiadiazine derivatives which act as kat inhibitors of the myst family.
A compound ... |
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|
Invention
|
Fused [1,2,4]thiadiazine derivatives which act as kat inhibitors of the myst family. A compound o... |
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2017
|
Invention
|
Pyridine derivatives and their use in the treatment of cancer and hemoglobinopathies. 7b is H.
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|
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Invention
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Benzopiperdine derivatives and their use in the treatment of cancer and hemoglobinopathies. 8b is... |
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Invention
|
Prmt5 inhibitors. 8d are H.
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|
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Invention
|
Tetrahydroisoquinolines as prmt5 inhibitors. 1-4 alkyl and cyano.
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|
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Invention
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Tetrahydroisoquinolines as prmt5 inhibitors. 8d are H.
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|
|
Invention
|
Tetrahydroisoquinolines as prmt5 inhibitors. A compound of formula (I) wherein: n is 1 or 2; p is... |
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|
Invention
|
Prmt5 inhibitors. A compound of formula (Ia), (Ib) or (Ic) wherein: n is 1 or 2; RN is H or Me; R... |
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|
Invention
|
Benzopiperidine derivatives and their use in the treatment of cancer and hemoglobinopathies. A co... |
|
|
Invention
|
Pyridine derivatives and thier use in the treatment of cancer and hemoglobinopathies. A compound ... |
|
|
Invention
|
Tetrahydroisoquinolines as prmt5-inhibitors. A compound of formula (I) wherein: n is 1 or 2; p is... |
|
|
Invention
|
3-oxa-8-azabicyclo[3.2.1]octane derivatives and thier use in the treatment of cancer and hemoglob... |
|
2015
|
Invention
|
Triazine compounds, compositions and synthesis. The present invention generally relates to triazi... |
|
|
Invention
|
Aminoindane-, aminotetrahydronaphthalene- and aminobenzocyclobutane-derived prmt5-inhibitors. 5-1... |
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|
Invention
|
Tetrahydroisoquinoline derived prmt5-inhibitors. 5-12 heteroaryl.
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