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2025
|
Invention
|
Lipid nanoparticles for inducing an immunological response. The present disclosure provides lipid... |
|
|
Invention
|
Lipid nanoparticles for stimulating t cells. The present disclosure provides lipid nanoparticles ... |
|
|
Invention
|
Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells.
... |
|
|
Invention
|
Block copolymers.
Described herein are block copolymers, and methods of making and utilizing suc... |
|
2024
|
Invention
|
Ionizable lipids suitable for lipid nanoparticles. The present disclosure provides nitrogen-conta... |
|
|
Invention
|
Pyrrolidine based cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stel... |
|
2023
|
Invention
|
Targeted compositions. The invention provides conjugates for the targeted delivery of therapeutic... |
|
|
Invention
|
Mannose-targeted compositions.
The invention provides compounds of formula (I) and salts thereof... |
|
|
Invention
|
Mannose-targeted compositions. The invention provides compounds of formula (I) and salts thereof,... |
|
|
Invention
|
Ionizable cationic lipids for lipid nanoparticles.
Certain embodiments of the invention provide ... |
|
|
Invention
|
Ionizable cationic lipids for lipid nanoparticles. Certain embodiments of the invention provide i... |
|
|
Invention
|
Poly(alkyloxazoline)-lipid conjugates and lipid particles containing same.
The present disclosur... |
|
|
Invention
|
Poly(alkyloxazoline)-lipid conjugates and lipid particles containing same. The present disclosure... |
|
2022
|
Invention
|
Mrna delivery constructs and methods of using the same.
The present disclosure provides, among o... |
|
|
Invention
|
Mrna delivery constructs and methods of using the same. The present disclosure provides, among ot... |
|
2021
|
Invention
|
Peg lipids and lipid nanoparticles.
The invention provides a compound of compound of formula (I)... |
|
|
Invention
|
Lipid nanoparticles for delivering therapeutics to lungs.
Certain embodiments of the invention p... |
|
|
Invention
|
Cationic lipids for lipid nanoparticle delivery of therapeutics to hepatic stellate cells.
Certa... |
|
2020
|
Invention
|
Conjugates and methods for treating liver fibrosis.
Provided herein are certain nucleic acids (e... |
|
|
Invention
|
Conjugates and methods for treating liver fibrosis. e.g.e.ge.g., in the setting of NASH or ASH. |
|
|
Invention
|
Conjugates and methods for treating acromegaly.
Provided herein are certain nucleic acids (e.g.,... |
|
|
Invention
|
Conjugates and methods for treating acromegaly. Provided herein are certain nucleic acids (e.g., ... |
|
|
Invention
|
Ornithine transcarbamylase (otc) constructs and methods of using the same.
The present disclosur... |
|
|
Invention
|
Ornithine transcarbamylase (otc) constructs and methods of using the same. The present disclosure... |
|
|
Invention
|
Block copolymers. Described herein are block copolymers, and methods of making and utilizing such... |
|
|
Invention
|
Lipid nanoparticles.
The invention provides lipid nanoparticles and formulations containing lipi... |
|
|
Invention
|
Lipid nanoparticles. The invention provides lipid nanoparticles and formulations containing lipid... |
|
2019
|
Invention
|
Therapeutic methods.
The invention provides methods and compositions for delivering a nucleic ac... |
|
|
Invention
|
Therapeutic methods. The invention provides methods and compositions for delivering a nucleic aci... |
|
|
Invention
|
Micellic assemblies. Provided herein are micellic assemblies comprising a plurality of copolymers... |
|
|
Invention
|
Nucleic acid constructs and methods of using the same. Described herein are block copolymers, and... |
|
2018
|
G/S
|
Pharmaceutical preparations for human use; biological
preparations for medical or therapeutic us... |
|
|
G/S
|
Pharmaceutical preparations for human use to treat genetic diseases and disorders and diseases an... |
|
|
G/S
|
Pharmaceutical preparations for human use for the treatment of genetic diseases and disorders and... |
|
|
G/S
|
Pharmaceutical preparations for human use for the treatment and prevention of genetic, infectious... |
|
2017
|
Invention
|
Branched peg molecules and related compositions and methods. Disclosed are branched PEG molecules... |
|
2016
|
Invention
|
Diblock copolymers and polynucleotide complexes thereof for delivery into cells. Described herein... |
|
|
Invention
|
Multiblock copolymers.
Provided herein are multiblock copolymers, as well as micelles and therap... |
|
|
Invention
|
Methods, compositions, and systems for delivering therapeutic and diagnostic agents into cells. D... |
|
2015
|
Invention
|
Bispecific intracellular delivery vehicles.
A composition for delivering an agent to a cell, com... |
|
|
Invention
|
Polymeric carrier.
Provided herein are polymeric carriers suitable for the delivery of polynucle... |
|
2014
|
Invention
|
Bispecific intracellular delivery vehicles. A composition for delivering an agent to a cell, comp... |
|
2010
|
Invention
|
Targeting monomers and polymers having targeting blocks. Provided herein are monomers incorporati... |
|
2009
|
Invention
|
Omega-functionalized polymers, junction-functionalized block copolymers, polymer bioconjugates, a... |
|
|
Invention
|
Multiblock copolymers. Provided herein are multiblock copolymers, as well as micelles and therape... |
|
|
Invention
|
Heterogeneous polymeric micelles for intracellular delivery. Compositions comprising a heterogene... |
