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2020
|
Invention
|
Caspase inhibitors and methods of use thereof. Provided herein are compounds of formula (I), comp... |
|
2019
|
Invention
|
(s)-3-(2-(4-(benzyl)-3-oxopiperazin-1-yl)acetamido)-4-oxo-5-(2,3,5,6-tetrafluorophenoxy)pentanoic... |
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2016
|
Invention
|
Methods of using caspase inhibitors in treatment of liver disease.
Provided herein are methods a... |
|
|
Invention
|
Methods of using caspase inhibitors in treatment of liver disease. Provided herein are methods an... |
|
|
Invention
|
Caspase inhibitors for the treatment of colorectal cancer.
Provided herein are methods and compo... |
|
|
Invention
|
Caspase inhibitors for use in the treatment of liver cancer. Provided herein are methods and comp... |
|
|
Invention
|
Treatment of the complications of chronic liver disease.
Provided herein are methods and composi... |
|
2015
|
Invention
|
Treatment of the complications of chronic liver disease with caspase inhibitors.
Provided herein... |
|
|
Invention
|
Treatment of the complications of chronic liver disease with caspase inhibitors. Provided herein ... |
|
2011
|
Invention
|
Solid forms of a phenoxybenzenesulfonyl compound. Provided herein are solid forms of 4-[4-(4-chlo... |
|
|
Invention
|
Combination therapy for the treatment of liver diseases.
Provided herein are methods for treatme... |
|
2008
|
Invention
|
Methods for the treatment of liver diseases.
Provided herein are methods for treatment of a live... |
|
|
Invention
|
Methods for the treatment of liver diseases. Provided herein are methods for treatment of a liver... |
|
|
Invention
|
Methods for the treatment of liver diseases using specified matrix metalloproteinase (mmp) inhibi... |
|
|
Invention
|
Combination therapy comprising matrix metalloproteinase inhibitors and caspase inhibitors for the... |
|
2007
|
Invention
|
Crystalline forms. The present invention relates to crystalline forms of (3S)-3-[N—(N′-(2-tert-bu... |
|
|
Invention
|
Crystalline forms of (3s)-3-[n-(n'-(2-tert-butylphenyl)oxamyl)alaninyl]amino-5-(2',3',5',6'-tetra... |
|
2005
|
G/S
|
PHARMACEUTICAL PREPARATIONS FOR THE TREATMENT AND PREVENTION OF ACUTE AND CHRONIC DISEASE RESULTI... |
|
2004
|
Invention
|
C-terminal modified oxamyl dipeptides as inhibitors of the ice/ced-3 family of cysteine proteases... |
|
2002
|
Invention
|
Treatment of inflammation-associated disorders using interleukin-1β-converting enzyme (ice)/ced-3... |
|
|
Invention
|
Membrane derived caspase-3, compositions comprising the same and methods of use therefor. Provide... |
|
|
Invention
|
Inhibition of apoptosis using interleukin-1β-converting enzyme (ice)/ced-3 family inhibitors. The... |
|
2001
|
Invention
|
Treatment of infectious disease using interleukin-1β-converting enzyme (ice)/ced-3 family inhibit... |
|
|
Invention
|
Inhibition of inflammation using interleukin-1β-converting enzyme (ice)/ced-3 family inhibitors. ... |
|
|
Invention
|
Inhibitors of the ice/ced-3 family of cysteine proteases. This invention is directed to novel oxa... |
|
2000
|
Invention
|
C-terminal modified (n-substituted)-2-indolyl dipeptides as inhibitors of the ice/ced-3 family of... |
|
1999
|
Invention
|
Human bad polypeptides, encoding nucleic acids and methods of use. The invention provides an isol... |
|
|
Invention
|
Rapid methods for identifying modifiers of cellular apoptosis activity. The invention provides a ... |
|
|
Invention
|
Methods for detecting membrane derived caspase activity and modulators thereof. Provided are meth... |
|
1998
|
Invention
|
Method of inhibiting nadph oxidase. The instant methods employs pharmaceutical compositions compr... |
|
1997
|
Invention
|
Inhibition of apoptosis using interleukin-1.beta.-converting enzyme (ice)/ced-3 family inhibitors... |
