2024
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Invention
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Morphic forms of cft7455 and methods of manufacture thereof.
An advantageous morphic form of Com... |
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Invention
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C3-carbon linked glutarimide degronimers for target protein degradation.
This invention provides... |
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Invention
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Selected compounds for targeted degradation of brd9.
Selected BRD9 protein degradation compounds... |
2023
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Invention
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Therapeutics for the degradation of mutant braf.
The present invention provides compounds or the... |
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Invention
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Egfr degraders to treat cancer metastasis to the brain or cns.
The invention provides for the tr... |
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Invention
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Glutarimides for medical treatment.
The present invention provides selected glutarimides which b... |
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Invention
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Dihydrobenzimidazolones for medical treatment.
The present invention provides selected dihydrobe... |
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Invention
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Isoindolinone and indazole compounds for the degradation of egfr.
The invention provides compoun... |
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Invention
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Tricyclic heterobifunctional compounds for degradation of targeted proteins.
Heterobifunctional ... |
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Invention
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Tricyclic ligands for degradation of ikzf2 or ikzf4.
Tricyclic compounds that degrade IKZF2 and/... |
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Invention
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Spirocyclic compounds.
The present invention provides compounds and intermediates. The present i... |
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Invention
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Advantageous therapies for disorders mediated by ikaros or aiolos.
New treatments for Ikaros and... |
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Invention
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Compounds for targeted degradation of ret.
Novel compounds which act as protein degradation indu... |
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Invention
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Spirocyclic compounds.
The present invention provides compounds which bind to the ubiquitously e... |
2022
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Invention
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Braf degraders.
Present invention provides compounds that cause specifically the degradation of ... |
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Invention
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Degraders and degrons for targeted protein degradation.
Pharmaceutical Degraders and Degrons for... |
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Invention
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Compounds for targeted degradation of brd9. BRD9 protein degradation compounds or pharmaceuticall... |
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Invention
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N/o-linked degrons and degronimers for protein degradation. This invention provides Degronimers t... |
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Invention
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Dihydroquinolinones for medical treatment. The present invention provides dihydroquinolinone comp... |
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Invention
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Isoindolinone and indazole compounds for the degradation of egfr. The invention provides compound... |
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Invention
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Compounds for targeting degradation of bruton's tyrosine kinase.
This disclosure relates to comp... |
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Invention
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Tricyclic degraders of ikaros and aiolos.
Tricyclic cereblon binders for the degradation of Ikar... |
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Invention
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Dihydrobenzimidazolones for medical treatment. The present invention provides selected dihydroben... |
2021
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Invention
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Compounds for targeted degradation of brd9. A BRD9 protein degrading compound of structure
or a... |
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Invention
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Spirocyclic degronimers for target protein degradation. This invention provides compounds that ha... |
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Invention
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Tricyclic degraders of ikaros and aiolos. Tricyclic cereblon binders for the degradation of Ikaro... |
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Invention
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Heterocyclic compounds for medical treatment.
The present invention provides heterocyclic compou... |
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Invention
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Targeted protein degradation.
This invention provides pharmaceutical protein degraders and E3 ub... |
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Invention
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Compounds for the degradation of brd9 or mth1.
Compounds that degrade BRD9 or MTH1 via the ubiqu... |
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Invention
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Heterocyclic degronimers for target protein degradation. This invention provides heterocyclic com... |
2020
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Invention
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Substituted piperidine degronimers for target protein degradation. 3-glutarimide Degronimers have... |
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Invention
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3-carbon linked glutarimide degronimers for target protein degradation. This invention provides D... |
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Invention
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Spirocyclic compounds. The present invention provides compounds and intermediates. The present in... |
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Invention
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Bifunctional compounds for the treatment of cancer.
The invention provides bifunctional compound... |
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Invention
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Bifunctional compounds.
The invention provides a bifunctional compound of formula (I), or a phar... |
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Invention
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Spirocyclic compounds. The present invention provides compounds which bind to the ubiquitously ex... |
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Invention
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Cereblon binders for the degradation of ikaros. The invention provides cereblon binders of Formul... |
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Invention
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Bifunctional molecules that degrade egfr.
The present invention provides compounds that cause sp... |
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Invention
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Bifunctional inhibitors with egfr having a e3 ubiquitin ligase moiety.
Present invention provide... |
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Invention
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Degraders and degrons for targeted protein degradation. Pharmaceutical Degraders and Degrons for ... |
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Invention
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Glutarimides for medical treatment. The present invention provides selected glutarimides which bi... |
2018
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Invention
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Amine-linked c3-glutarimide degronimers for target protein degradation.
This invention provides ... |
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Invention
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C3-carbon linked glutarimide degronimers for target protein degradation. This invention provides ... |