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2023
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Invention
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Novel linker drugs comprising phosphoantigens, novel conjugates and their use in therapy. The pre... |
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Invention
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Dual conjugation process for preparing antibody-drug conjugates. The present invention relates to... |
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Invention
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Novel masked antibodies.
The present invention provides a masked antibody or antigen binding fra... |
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Invention
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Novel masked antibodies. The present invention provides a masked antibody or antigen binding frag... |
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2022
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Invention
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Antifolate linker-drugs and antibody-drug conjugates.
The present invention relates to novel ant... |
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Invention
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Antifolate linker-drugs and antibody-drug conjugates. The present invention relates to novel anti... |
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Invention
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Conjugates comprising phosphoantigens and their use in therapy.
The present invention relates to... |
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Invention
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Conjugates comprising phosphoantigens and their use in therapy. The present invention relates to ... |
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Invention
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Anti-c-met antibodies and antibody-drug conjugates.
The present invention relates to antibodies ... |
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Invention
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Anti-c-met antibodies and antibody-drug conjugates. The present invention relates to antibodies o... |
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Invention
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Anti-sirp α antibodies. The invention relates to antibodies against SIRPα that are suitable for u... |
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2021
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Invention
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Site-specific conjugation of linker drugs to antibodies and resulting adcs. The present invention... |
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Invention
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Anti-5t4 antibodies and antibody-drug conjugates. The present invention relates to antibodies aga... |
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Invention
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Combination containing a duocarmycin derivative-comprising antibody-drug conjugate and thiosulfat... |
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2020
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G/S
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Scientific and technological services, including associated research services; pharmaceutical res... |
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G/S
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Scientific and technological services, namely, scientific research, analysis, testing, diagnostic... |
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G/S
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Pharmaceutical preparations, substances and compositions; biological and biochemical drug and cul... |
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G/S
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Pharmaceutical preparations for the treatment of cancer. |
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G/S
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Pharmaceutical preparations for the treatment of cancer. |
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G/S
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Biopharmaceutical preparations, substances and compositions, namely, antibacterial substances for... |
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G/S
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Pharmaceutical preparations, substances and substances;
biological and biochemical medicines and... |
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2019
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Invention
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Humanized anti-sirpα antibodies. The present invention relates to humanized antibodies against SI... |
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Invention
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Filterable duocarmycin-containing antibody-drug conjugate compositions and related methods. Duoca... |
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G/S
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Treatment of materials, including on request, for others, for the purpose of manufacturing pharma... |
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G/S
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Pharmaceutical preparations, substances and compositions; biological and biochemical drugs and cu... |
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G/S
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Pharmaceutical preparations, substances and compositions; Biological and biochemical drug and Cul... |
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Invention
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Duocarmycin adcs showing improved in vivo antitumor activity. The present invention relates to du... |
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G/S
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Pharmaceutical preparations for the treatment of cancer |
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2018
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Invention
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Process for the synthesis of linker-drug vc-seco-duba. The compound of formula (II) is an advanta... |
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Invention
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Anti-sirpα antibodies. The present invention relates to antibodies against SIRPα that are suitabl... |
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2017
|
Invention
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Process for the preparation of mono-protected α,ω-diamino alkanes. The present invention relates ... |
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Invention
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Non-linear self-immolative linkers and conjugates thereof. The present invention relates to linke... |
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Invention
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Conjugates of cc-1065 analogs and bifunctional linkers. This invention relates to novel analogs o... |
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Invention
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Selective reduction of cysteine-engineered antibodies. The present invention relates to a process... |
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2016
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Invention
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Anti-5t4 antibodies and antibody-drug conjugates. The present disclosure relates to CDR defined a... |
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Invention
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Syd985 treatment of t-dm1 refractory cancer patients. The present invention relates to the duocar... |
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Invention
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Duocarmycin adcs for use in treatment of endometrial cancer. The present invention relates to duo... |
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Invention
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Compositions comprising antibody-duocarmycin drug conjugates. The present invention relates to ly... |
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2015
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Invention
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Method for purifying cys-linked antibody-drug conjugates. The present invention relates to a meth... |
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2014
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Invention
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Cc-1065 analogs and their conjugates. This invention relates to novel analogs of the DNA-alkylati... |
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Invention
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Process for making duocarmycin prodrugs. The present invention relates to a process comprising co... |
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2012
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Invention
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Monoclonal antibodies to human proinflammatory cytokines and methods for treating inflammatory di... |
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Invention
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Anti-tnf alpha monoclonal secretory iga antibodies and methods for treating inflammatory diseases... |
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Invention
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Method of purifying an antibody. A method of purifying an antibody composition comprises applicat... |
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2006
|
Invention
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Triazole-containing releasable linkers, conjugates thereof, and methods of preparation. This inve... |
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2004
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Invention
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Elongated and multiple spacers in activatible prodrugs. m: k+l+m≧1, and if k+l+m=1; —when A is U:... |
