2024
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Invention
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Eed inhibitor solid dispersion, oral formulation comprising same, and preparation method therefor... |
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Invention
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Bcl-2/bcl-xl protein degrader and use thereof. Provided are compounds that function as degraders ... |
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Invention
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Methods of treating tki-resistant and sdh-deficient gist. Provided herein is a method of treating... |
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Invention
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Pharmaceutical composition and use thereof. A pharmaceutical composition and the use thereof. Spe... |
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Invention
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Kras inhibitors. The present disclosure relates to compounds that inhibit KRAS. In particular, th... |
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Invention
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Crystal form of alk inhibitor or salt and solvate thereof, preparation method therefor, and use t... |
2023
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Invention
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Methods for cancer therapy.
The present invention relates to methods for treating patients with ... |
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Invention
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Combination therapies for treating cancer.
The present invention relates to one or more combinat... |
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Invention
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Tricyclic heterocycle compounds as iap antagonists. The present disclosure relates to compounds t... |
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Invention
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Methods for treating immune diseases. Methods for treating immune diseases, specifically methods ... |
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Invention
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Crystalline form or amorphous form of macrocyclic compound or salt or solvate thereof. Disclosed ... |
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Invention
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Methods for treating aml-mrc and mds. Provided are methods for treating hematologic malignancy, e... |
2022
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Invention
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Kras inhibitors. Disclosed relates to compounds that inhibit KRAS. In particular, disclosed relat... |
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Invention
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Methods of treating a disease or disorder.
Disclosed is a method for preventing and/or treating ... |
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Invention
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Methods of treating a disease or disorder. Disclosed is a method for preventing and/or treating a... |
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Invention
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Pharmaceutical combination and use thereof. The present invention relates to the field of medicin... |
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Invention
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A pharmaceutical combination and use thereof.
Provided herein are the pharmaceutical combination... |
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Invention
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A pharmaceutical combination and use thereof. Provided herein are the pharmaceutical combination ... |
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Invention
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Pharmaceutical compositions and preparation methods thereof. It provides a pharmaceutical composi... |
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Invention
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Sulfonyl benzamide derivatives as bcl-2 inhibitors.
The present disclosure provides compounds ha... |
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Invention
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Sulfonyl benzamide derivatives as bcl-2 inhibitors. The present disclosure provides compounds hav... |
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Invention
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Spirocyclic indenes. Provides compounds represented by Formula(I): wherein R 3, R 8c, R 8d, A, A ... |
2021
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Invention
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Methods of treating multiple sclerosis.
Disclosed are methods of treating multiple sclerosis. Th... |
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Invention
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Methods of treating multiple sclerosis. Disclosed are methods of treating multiple sclerosis. The... |
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Invention
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A composition comprising heterocyclic compounds, preparation method and application thereof.
Pro... |
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Invention
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A pharmaceutical composition and use thereof for treatment of cancer.
Provided herein in the bio... |
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Invention
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Compositions and methods for treating non-alcoholic steatohepatitis.
Methods for treating non-al... |
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Invention
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Compositions and methods for treating systemic lupus erythematosus.
Methods for treating systemi... |
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Invention
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The crystalline forms or amorphous forms of bisdiazabicyclic compounds or salts thereof.
Crystal... |
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Invention
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Crystalline or amorphous form of bcl-2/bcl-xl inhibitor compound or its salts.
Disclosed herein ... |
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Invention
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Methods for synthesizing n-(phenylsulfonyl)benzamide compounds and intermediates thereof.
Disclo... |
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Invention
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Crystals of alkynyl-containing compound, salt and solvate thereof, preparation method, and applic... |
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Invention
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Microsuspension of an mdm2 inhibitor and therapeautic applications thereof.
Provided herein is a... |
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Invention
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Preparation method of (5-fluoro-2,3-dihydrobenzofuran-4-yl)methanamine or its salt, and intermedi... |
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Invention
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Methods for treating coronavirus infections.
A method for treating patients with viral infection... |
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Invention
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Novel medical use of mdm2 inhibitors.
Provided use of MDM2 inhibitors alone or in combination wi... |
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Invention
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Combinations of bcl-2/bcl-xl inhibitors and related uses.
The present disclosure relates to comb... |
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Invention
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Crystalline forms or amorphous forms of n-(phenyl sulfonyl) benzamide compounds or its salts or s... |
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Invention
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Amorphous form or crystalline form of 2-indolinolinololylspironone compounds or their salts, sol... |
2020
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Invention
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Pharmaceutical combination and use thereof.
Described herein are methods of treating a cancer, f... |
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Invention
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N-(phenylsulfonyl)benzamides and related compounds as bcl-2 inhibitors.
Described herein are met... |
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Invention
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Combination of iap inhibitors and parp or mek inhibitors or other chemotherapeutic agents.
A pha... |
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Invention
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Method and compositions for predicting anti-cancer efficacy of compounds targeting apoptosis path... |
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G/S
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Medicines for dental purposes; Chemical preparations for medical purposes for treating cancer, tu... |
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Invention
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Heterocyclic compounds as bcr-abl inhibitors.
The present disclosure provides compounds represen... |
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Invention
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Tricyclic compounds as bcr-abl inhibitors. 6, m, and p are defined herein. Compounds of Formula I... |
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Invention
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Method and composition for predicting efficacy of bcl2/bcl-xl inhibitors on cancer.
Provided are... |
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Invention
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Macrocyclic fused pyrrazoles as mcl-1 inhibitors.
Provided are compounds represented by Formula ... |
2019
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Invention
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Pharmaceutical composition containing alkynyl compound and preparation method and application the... |
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Invention
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Macrocyclic indoles as mcl-1 inhibitors. 3, #, #, # are as defined as set forth in the re) specif... |