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2024
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Invention
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Chemical compounds and uses thereof. Disclosed herein are certain chemical compounds of Formula (... |
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Invention
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Chemical compounds and uses thereof. Disclosed herein are certain chemical compounds that inhibit... |
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Invention
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Thiadiazolyl derivatives as dna polymerase theta inhibitors and uses thereof.
Disclosed herein a... |
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G/S
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Pharmaceutical and biological preparations; Pharmaceutical and biological preparations for use in... |
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Invention
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Methods of treating hepatic-only metastatic uveal melanoma. Provided herein is a method of treati... |
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Invention
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Combination therapy comprising a mat2a inhibitor and a topoisomerase inhibitor, a splicing inhibi... |
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Invention
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Combination therapy comprising a parg inhibitor and a topoisomerase inhibitor for treating cancer... |
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Invention
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Heteroaryl-substituted benzimidazole compounds. Provided herein are compounds having the formula:... |
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Invention
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Heteroaryl-substituted pyrazolo/imidazo pyridine compounds. Provided herein are compounds having ... |
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Invention
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Heteroaryl-substituted imidazopyridine compounds. Provided herein are compounds having the formul... |
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Invention
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Amide and ester-substituted imidazopyridine compounds. Provided herein are compounds having the f... |
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Invention
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Treatment of er+ breast cancer comprising homologous recombination deficiency using parc inhibito... |
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Invention
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Combination therapy comprising a mat2a inhibitor and a type ii prmt inhibitor. Provided herein is... |
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2023
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Invention
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Thiadiazolyl derivatives as dna polymerase theta inhibitors and uses thereof. Disclosed herein ar... |
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Invention
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Cancer treatments using a prmt5 inhibitor and a mat2a inhibitor. Described herein are methods of ... |
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Invention
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Combination therapy comprising a mat2a inhibitor and a prmt5 inhibitor. Provided herein is a comb... |
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Invention
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Atropisomers of mat2a inhibitors. Disclosed herein are atropisomers of Formula (I) that are methi... |
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G/S
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Pharmaceutical and biological preparations, namely, an orally administered protein kinase C (PKC)... |
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Invention
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Combination therapy comprising a mat2a inhibitor and a type ii prmt inhibitor.
Provided herein i... |
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Invention
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Methods of treating uveal melanoma with a pkc inhibitor. inter aliainter alia, ocular tumors in u... |
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Invention
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Methods of treating uveal melanoma. Provided herein is a combination therapy and methods of using... |
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Invention
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Combination therapy comprising a mat2a inhibitor and a parp inhibitor. Provided herein is a combi... |
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Invention
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Methionine adenosyltransferase 2a inhibitors. Disclosed herein are compounds of Formula (I): or a... |
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Invention
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Piperazine substituted indazole compounds as inhibitors of parg.
Provided herein are compounds o... |
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Invention
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Piperazine substituted indazole compounds as inhibitors of parg. Provided herein are compounds of... |
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Invention
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Combination therapy comprising a mat2a inhibitor and an antimetabolite agent. Provided herein is ... |
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2022
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Invention
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Combination therapy comprising a pkc inhibitor and a c-met inhibitor.
Provided herein is a combi... |
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Invention
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Combination therapy comprising a pkc inhibitor and a c-met inhibitor. Provided herein is a combin... |
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Invention
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2-oxoquinazoline crystalline forms. The present disclosure provides crystalline forms of the comp... |
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Invention
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Combination therapy comprising a mat2a inhibitor and a taxane. Provided herein is a combination o... |
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Invention
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Thiadiazolyl compounds as dna polymerase theta inhibitors. Disclosed herein are certain thiadiazo... |
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Invention
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Cyclic vinyl sulfone compounds as wrn inhibitors. Disclosed herein are certain succinamido deriva... |
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Invention
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Ahr modulators.
Provided herein are compounds, compositions and methods of using the compounds a... |
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Invention
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O-linked thiadiazolyl compounds as dna polymerase theta inhibitors.
Disclosed herein are certain... |
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Invention
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O-linked thiadiazolyl compounds as dna polymerase theta inhibitors. Disclosed herein are certain ... |
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Invention
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Combination therapy comprising a mat2a inhibitor and type i prmt inhibitor.
Provided herein is a... |
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Invention
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Combination therapy comprising a mat2a inhibitor and type i prmt inhibitor. Provided herein is a ... |
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2021
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Invention
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Pharmaceutical combination and tumor treatment.
A combination therapy is described involving a s... |
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Invention
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Cyclized acetamido derivatives as dna polymerase theta inhibitors.
The present invention relates... |
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Invention
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Heteroaryl alkylene substituted 2-oxoquinazoline derivatives as methionine adenosyltransferase 2a... |
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Invention
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2-aminoquinazolinone derivatives as methionine adenosyltransferase 2a inhibitors.
Disclosed here... |
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Invention
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4-arylquinazoline derivatives as methionine adenosyltransferase 2a inhibitors.
Disclosed herein ... |
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Invention
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Quinolinone derivatives as methionine adenosyltransferase 2a inhibitors.
Disclosed herein are ce... |
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2020
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Invention
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Dosing regimens for a protein kinase c inhibitor.
Disclosed herein are dosing regimens for the t... |
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Invention
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4-substituted indole and indazole sulfonamido derivatives as parg inhibitors.
Provided herein ar... |
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Invention
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Thiadiazolyl derivatives.
Disclosed herein are certain thiadiazolyl derivatives Formula (I):
D... |
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2019
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Invention
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Methods of culturing and/or expanding stem cells and/or lineage committed progenitor cells using ... |
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2017
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G/S
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Small molecule compounds for use in therapeutic
pharmaceuticals for the treatment of oncology. |
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2016
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G/S
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Small molecule compounds for use in therapeutic pharmaceuticals for the treatment of oncology |
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G/S
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Small molecule therapeutic pharmaceuticals for the treatment of cancer |
