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2024
|
Invention
|
Treatment of cancers using pi3 kinase isoform modulators.
Provided herein are methods, kits, and... |
|
|
Invention
|
Processes for preparing isoquinolinones and solid forms of isoquinolinones.
Polymorphs of chemic... |
|
|
Invention
|
Combination therapies.
Provided herein are pharmaceutical compositions comprising a phosphatidyl... |
|
2022
|
Invention
|
Formulations of (s)-3-(1-(9h-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2h)-one.
Poly... |
|
2021
|
Invention
|
Eganelisib for use in the treatment of pd-l1 negative cancer. Compounds and pharmaceutical compos... |
|
|
Invention
|
Combination therapies. Provided herein are pharmaceutical compositions comprising a phosphatidyli... |
|
2020
|
Invention
|
Methods of use of cyclopamine analogs. The invention provides methods for treating various condit... |
|
|
Invention
|
Treatment of cancers using pi3 kinase isoform modulators. Provided herein are methods, kits, and ... |
|
|
Invention
|
Formulations of (s)-3-(1-(9h-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2h)-one. Polym... |
|
2019
|
Invention
|
Heterocyclic compounds and uses thereof.
Compounds and pharmaceutical compositions that modulate... |
|
|
G/S
|
Pharmaceutical preparations for the diagnosis and treatment of oncological and inflammatory disea... |
|
2018
|
Invention
|
Methods of treating a fatty acid amide hydrolase-mediated condition.
The present invention provi... |
|
2017
|
Invention
|
Solid forms of (s)-3-(1-(9h-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1(2h)-one and met... |
|
|
Invention
|
Heterocyclic compounds and uses thereof. Compounds and pharmaceutical compositions that modulate ... |
|
|
Invention
|
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhib... |
|
2016
|
Invention
|
Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and method... |
|
|
Invention
|
Tetrazolones as inhibitors of fatty acid synthase.
Provided herein are tetrazolone FASN inhibito... |
|
|
Invention
|
Enzymatic transamination of cyclopamine analogs. The invention relates to the preparation of amin... |
|
|
Invention
|
Processes for preparing isoquinolinones and solid forms of isoquinolinones. Polymorphs of chemica... |
|
|
Invention
|
Isolation of cyclopamine.
Provided are deglycosylation methods designed to optimize the yield of... |
|
|
Invention
|
Solid forms of (s)-3-(1-(9h-purin-6-ylamino)ethyl)-8-chloro-2-phenylisoquinolin-1 (2h)-one and me... |
|
2015
|
Invention
|
Treatment of rheumatoid arthritis and asthma using pi3 kinase inhibitors.
Provided herein are me... |
|
|
Invention
|
Heterocyclic compounds and uses thereof. Compounds of formula I' and formula II' and their pharma... |
|
|
Invention
|
Chemical compounds, compositions and methods for kinase modulation. Substituted isoquinolinone co... |
|
|
Invention
|
Inhibitors of fatty acid amide hydrolase, methods of treatment and methods of preparing same.
Th... |
|
|
Invention
|
Treatment of pulmonary or respiratory diseases by inhalation administration of pi3 kinase inhibit... |
|
|
Invention
|
Pyrimidine or pyridine derivatives useful as pi3k inhibitors. Compounds (I) and pharmaceutical co... |
|
|
Invention
|
Combination of a pi3k inhibitor with a bcl-2 inhibitor for use in the treatment of cancer. Provid... |
|
|
Invention
|
Inhibitors of fatty acid amide hydrolase.
The present invention provides compounds, and pharmace... |
|
2014
|
G/S
|
Pharmaceutical preparations for the diagnosis and treatment of cancer and inflammatory diseases a... |
|
|
Invention
|
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same... |
|
2002
|
G/S
|
Diagnostic assays and test kits for clinical, laboratory and chemical use to diagnose, prognose, ... |
