|
2023
|
Invention
|
Solid dose pharmaceutical composition.
The present disclosure provides pharmaceutical compositio... |
|
2022
|
Invention
|
Cdk9 inhibitors and polymorphs thereof for use as agents for treatment of cancer. A crystalline f... |
|
|
Invention
|
Imidazo[1,2-b]pyridazinyl compounds and uses thereof.
Provided herein are compounds of the follo... |
|
|
Invention
|
Imidazo[1,2-b]pyridazinyl compounds and uses thereof. Provided herein are compounds of the follow... |
|
|
Invention
|
Axl kinase inhibitors and use of the same.
Tartrate salts of the compound of structure (I),
Ta... |
|
|
Invention
|
Alk-5 inhibitors and uses thereof. Provided herein are compounds (e.g., compounds of Formulae (I)... |
|
|
Invention
|
Alk-5 inhibitors and uses thereof.
Provided herein are compounds (e.g., compounds of Formulae (I... |
|
|
Invention
|
(furopyrimidin-4-yl)piperazine compounds and uses thereof. Provided herein are compounds of the f... |
|
|
Invention
|
Alk-5 inhibitors and uses thereof. in vitroin vivoin vivo. |
|
|
Invention
|
Forms and formulations of a tyrosine kinase non-receptor 1 (tnk1) inhibitor.
Provided herein are... |
|
|
Invention
|
Forms and formulations of a tyrosine kinase non-receptor 1 (tnk1) inhibitor. Provided herein are ... |
|
2021
|
Invention
|
Methods for treating castration-resistant and castration-sensitive prostate cancer.
Methods of t... |
|
|
Invention
|
Alk-5 inhibitors and uses thereof. e.ge.ge.ge.gin vitro or in vivoin vitro or in vivo. Also provi... |
|
|
Invention
|
Alvocidib prodrugs having increased bioavailability.
Compounds having the following structure (I... |
|
|
Invention
|
Aminopyrimidinylaminobenzonitrile derivatives as nek2 inhibitors.
The present invention provides... |
|
2020
|
Invention
|
Combination therapies for treatment of myelodysplastic syndrome.
The present invention relates t... |
|
|
Invention
|
Axl kinase inhibitors and use of the same. Tartrate salts of the compound of structure (I),
cry... |
|
|
Invention
|
Axl inhibitor formulations.
Formulations of Compound 1 or a pharmaceutically acceptable salt the... |
|
|
Invention
|
Combination therapies for treatment of cancer.
Combination therapies for treatment of cancer are... |
|
|
Invention
|
Process for producing a hydrate of a hydrochloride salt of 2,2′-((((((2-acetylnaphtho[2,3-b]furan... |
|
|
Invention
|
Jak2 and alk2 inhibitors and methods for their use.
Compounds having activity as inhibitors of A... |
|
|
Invention
|
Treatment of cancer.
Provided herein are methods of treating a hematologic cancer in a subject i... |
|
|
Invention
|
Tyrosine kinase non-receptor 1 (tnk1) inhibitors and uses thereof. Provided herein is a compound ... |
|
|
Invention
|
Pkm2 modulators and methods for their use.
Compounds having activity as PKM2 activators are disc... |
|
|
Invention
|
Treatment of acute myeloid leukemia (aml) with venetoclax failure. Provided herein are various re... |
|
|
Invention
|
Compositions comprising pkm2 modulators and methods of treatment using the same. A compound of St... |
|
|
Invention
|
Combination therapies for treatment of cancer. Combination therapies for treatment of cancer are ... |
|
|
Invention
|
Predicting response to alvocidib by mitochondrial profiling.
The present disclosure provides dia... |
|
|
Invention
|
Formulations comprising heterocyclic protein kinase inhibitors. Provided is a composition compris... |
|
|
Invention
|
Alk5 inhibitors for treating myelodysplastic syndrome. Described herein are methods for treating ... |
|
2019
|
Invention
|
Methods to target transcriptional control at super-enhancer regions.
Methods for targeting super... |
|
|
Invention
|
Cyclin-dependent kinase inhibitors in combination with anthracyclines for treatment of cancer.
M... |
|
|
Invention
|
Methods for monitoring tumor lysis syndrome.
Provided herein are methods for monitoring the deve... |
|
|
Invention
|
Deuterated alvocidib and alvocidib prodrugs.
Provided herein are compounds having the following ... |
|
|
Invention
|
Materials and methods for treating cancer.
This document provides methods for determining biolog... |
|
2018
|
Invention
|
Pkm2 activators in combination with reactive oxygen species for treatment of cancer.
Combination... |
|
|
Invention
|
Treatment regimen for cancers that are insensitive to bcl-2 inhibitors using the mcl-1 inhibitor ... |
