2024
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Invention
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Substituted 1,1'-biphenyl compounds, analogues thereof, and methods using same.
The present inve... |
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G/S
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Pharmaceutical preparations for the treatment of hepatitis. |
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Invention
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Novel lipids and compositions for the delivery of therapeutics.
The present invention provides l... |
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Invention
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Novel lipid formulations for delivery of therapeutic agents.
The present invention provides nove... |
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Invention
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Improved methods for synthesis of 5-(aminomethyl)pyrrolidin-2-one compounds. The present disclosu... |
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Invention
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Lipid formulations for delivery of therapeutic agents. The present invention provides novel, seru... |
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Invention
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Non-liposomal systems for nucleic acid delivery. The present invention provides novel, stable lip... |
2023
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Invention
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Substituted arylamine compounds, substituted heteroarylamine compounds, and methods using same. T... |
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Invention
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Substituted 1-arylaminocarbonyl-1'-heteroaryl compounds, substituted 1-heteroarylaminocarbonyl-1'... |
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Invention
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Synthesis of substituted 1-aryl-1'-heteroaryl compounds and substituted 1,1'-biheteroaryl compoun... |
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Invention
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Synthesis of substituted tetracyclic carboxylic acids and analogues thereof. The present disclosu... |
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Invention
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Substituted imidazoamide compounds, and methods using same. The present disclosure includes subst... |
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Invention
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Non-liposomal systems for nucleic acid delivery.
The present invention provides novel, stable li... |
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Invention
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Lipid formulations for nucleic acid delivery.
The present invention provides novel, stable lipid... |
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Invention
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Lipids and compositions for the delivery of therapeutics. The present invention provides lipids t... |
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Invention
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Lipid compositions. Disclosed herein are lipid compositions comprising a cationic lipid of formul... |
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Invention
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Rna polymerase inhibitors and methods using same. The present disclosure relates to compounds of ... |
2022
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Invention
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Pro) inhibitors and methods using same. The present disclosure relates to compounds, and composit... |
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Invention
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Synthesis of substituted tricyclic amides and analogues thereof.
The present disclosure includes... |
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Invention
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Synthesis of substituted tricyclic amides and analogues thereof. The present disclosure includes ... |
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Invention
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Targeted compositions. The invention provides certain nucleic acids (e.g., double stranded siRNA ... |
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Invention
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Methods for ameliorating infusion reactions. Certain embodiments of the invention provide methods... |
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Invention
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Substituted tetracyclic carboxylic acids, analogues thereof, and methods using same. The present ... |
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Invention
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Substituted 1-aryl-1’-heteroaryl compounds, substituted 1,1’-biheteroaryl compounds, and methods ... |
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Invention
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Substituted 1-aryl-1'-heteroaryl compounds, substituted 1,1'-biheteroaryl compounds, and methods ... |
2021
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Invention
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Targeted conjugates comprising modified sirna. The invention provides certain nucleic acids (e.g.... |
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Invention
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Lipids and compositions for the delivery of therapeutics. 10 alkynyl, alkylhetrocycle, alkylphosp... |
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Invention
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Synthesis of substituted arylmethylureas, analogues, and crystalline forms thereof and methods of... |
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Invention
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Substituted (phthalazin-1-ylmethyl)ureas, substituted n-(phthalazin-1-ylmethyl)amides, and analog... |
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Invention
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Substituted isoquinolinylmethyl amides, analogues thereof, and methods using same.
The present d... |
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Invention
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Substituted isoquinolinylmethyl amides, analogues thereof, and methods using same. The present di... |
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Invention
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Substituted tricyclic amides, analogues thereof, and methods using same.
The present invention i... |
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Invention
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Methods of delivering oligonucleotides to immune cells.
The invention relates to the field of de... |
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Invention
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Lipid compositions.
Disclosed herein are lipid compositions comprising a cationic lipid of formu... |
2020
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Invention
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Substituted bicyclic and tricyclic ureas and amides, analogues thereof, and methods using same.
... |
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Invention
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Substituted isoindolonyl 2,2'-bipyrimidinyl compounds, analogues thereof, and methods using same.... |
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Invention
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Substituted cyclopropyl-2,2'-bipyrimidinyl compounds, analogues thereof, and methods using same. ... |
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Invention
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Substituted polycyclic carboxylic acids, analogues thereof, and methods using same.
The present ... |
2019
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Invention
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Substituted arylmethylureas and heteroarylmethylureas, analogues thereof, and methods using same.... |
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Invention
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Cationic lipids containing silicon.
Certain embodiments of the invention provide a cationic lipi... |
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Invention
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Negatively charged peg-lipid conjugates.
The invention provides PEG-conjugated lipids of formula... |
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Invention
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Lipid nanoparticle formulations.
The invention provides certain specific lipid nanoparticles com... |
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Invention
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Bivalent targeted conjugates.
The invention provides conjugates that comprise a bivalent targeti... |
2018
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Invention
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Therapeutic compositions and methods for treating hepatitis b.
The invention provides therapeuti... |
2017
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G/S
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Drug discovery for others in the nature of pharmaceutical research and development. |