2024
|
Invention
|
Ionizable cationic lipids for rna delivery.
The present disclosure describes compounds of Formul... |
|
Invention
|
Ionizable cationic lipids for rna delivery. The present disclosure describes compounds of Formula... |
|
Invention
|
Hbv gene editing. Provided herein are compositions that include mRNA molecules encoding transcrip... |
|
Invention
|
Lipid nanoparticles encapsulation of large rna.
A method of producing lipid-encapsulated RNA nan... |
|
Invention
|
Methods and compositions for quadrivalent influenza vaccine.
Provided herein are RNA molecules e... |
|
Invention
|
Methods and compositions for quadrivalent influenza vaccine. Provided herein are RNA molecules en... |
2023
|
Invention
|
Method of making lipid-encapsulated rna nanoparticles.
A method of producing a lipid-encapsulate... |
|
Invention
|
Nucleic acid vaccine composition comprising a lipid formulation, and method of increasing the pot... |
|
Invention
|
Compositions and methods for inducing immune responses.
Provided herein are nucleic acid molecul... |
|
Invention
|
Coronavirus vaccine compositions and methods.
Provided herein are nucleic acid molecules encodin... |
|
Invention
|
Methods for in vitro transcription.
Disclosed herein are methods of producing transcribed RNA pr... |
|
Invention
|
Improved methods for in vitro transcription. Disclosed herein are methods of producing transcribe... |
|
Invention
|
Compositions and methods for treating ornithine transcarbamylase deficiency.
The present disclos... |
2022
|
Invention
|
Lipid formulations containing nucleic acids and methods of treatment for cystic fibrosis.
Lipid ... |
|
Invention
|
Lipid formulations containing nucleic acids and methods of treatment for cystic fibrosis. in vitr... |
|
Invention
|
Lipid formulations containing nucleic acids and methods of treatment for cystic fibrosis. Lipid f... |
|
Invention
|
Compositions and methods for treating phenylketonuria. Phenylketonuria (PKU) is caused by a mutat... |
|
Invention
|
Rna vaccines.
Provided herein are RNA molecules encoding viral replication proteins and antigeni... |
|
Invention
|
Synthetic transfer rna with extended anticodon loop. The invention relates to a synthetic transfe... |
|
Invention
|
Rna vaccines. Provided herein are RNA molecules encoding viral replication proteins and antigenic... |
|
Invention
|
Translatable molecules and synthesis thereof. A range of therapeutic mRNA molecules expressible t... |
|
Invention
|
Peptide-lipid conjugates.
Peptides and Peptide-lipid conjugates are provided in which the peptid... |
|
Invention
|
Lipid compositions comprising peptide-lipid conjugates.
A lipid composition containing a nucleic... |
|
Invention
|
Lipid compositions comprising peptide-lipid conjugates. A lipid composition containing a nucleic ... |
|
Invention
|
Peptide-lipid conjugates. Peptides and Peptide-lipid conjugates are provided in which the peptide... |
2021
|
Invention
|
Compositions and methods for treating metabolic disorders.
Provided herein are compositions and ... |
|
Invention
|
Compositions and methods for treating metabolic disorders. Provided herein are compositions and m... |
|
Invention
|
Transcription activator-like effector nucleases (talens) targeting hbv.
Nucleic acid molecules e... |
|
Invention
|
Transcription activator-like effector nucleases (talens) targeting hbv. Nucleic acid molecules en... |
|
Invention
|
Lipid nanoparticles encapsulation of large rna. st tube comprising a turbulent flow of the RNA an... |
|
Invention
|
Lipid nanoparticles encapsulation of large rna. A method of producing lipid-encapsulated RNA nano... |
|
Invention
|
Method of lyophilizing lipid nanoparticles. Methods of preparing lyophilized lipid nanoparticle-n... |
|
Invention
|
Una oligomers for the treatment of polyglutamine diseases.
An oligomer comprising a sense strand... |
|
Invention
|
Una oligomers for the treatment of polyglutamine diseases.
A method for inhibiting expression of... |
2020
|
G/S
|
Vaccine preparations. |
|
G/S
|
Biological compounds for medical use in the nature of
enhanced ribonucleic acid delivered into p... |
|
Invention
|
Improved in vitro transcription purification platform.
Provided herein are methods for purificat... |
|
G/S
|
Vaccine preparations for preventing infection by coronavirus |
|
Invention
|
Synthetic transfer rna with extended anticodon loop.
The invention relates to a synthetic transf... |
|
G/S
|
Biological compound for medical use, namely, enhanced ribonucleic acid delivered into patient cel... |
2019
|
Invention
|
Modified proteins and associated methods of treatment.
The present disclosure provides a modifie... |
|
Invention
|
Lipid particles for nucleic acid delivery. Nucleic acid immunization is achieved by delivering a ... |
|
Invention
|
Ionizable cationic lipid for rna delivery. What is described is a compound of formula (1)
or a ... |
2015
|
G/S
|
Pharmaceutical preparations, namely, a lipid-enabled drug delivery system for RNA medicines compr... |
2014
|
G/S
|
Pharmaceutical intermediate products, namely a lipid-enabled drug delivery system for RNA medicin... |