The present specification discloses recombinant nucleic acid constructs encoding an immunogenic multiepitope polypeptide comprising two or more polypeptides, recombinant nucleic acid constructs encoding at least two epitopes from two or more internal proteins of influenza virus, compositions comprising such recombinant nucleic acid constructs and methods of eliciting a T cell immune response against an influenza virus in a vertebrate using such recombinant nucleic acid constructs and compositions.
The present specification discloses Trypanosoma antigens, immunogenic compositions and medicaments comprising such Trypanosoma antigens, methods and uses for such Trypanosoma antigens and immunogenic compositions for treating a Trypanosoma-based disease.
C07K 14/44 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de protozoaires
from polypeptide sequences having 85% homology or more with one or more of the above sequences and contained in one or more of the following databases: GenBank, Protein Data Bank (PDB), SwissProt, Protein Information Resource (PIR), Protein Research Foundation (PRF), or CDS translations of these.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
The present specification discloses Trypanosoma antigens, immunogenic compositions and medicaments comprising such Trypanosoma antigens, methods and uses for such Trypanosoma antigensand immunogenic compositions for treating a Trypanosoma-based disease.
C07K 14/44 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de protozoaires
5.
Chagas antigens and antibodies and compositions, methods and uses thereof
C07K 14/44 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains provenant de protozoaires
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
6.
HIV ANTIGENS AND ANTIBODIES AND COMPOSITIONS, METHODS AND USES THEREOF
The present specification discloses HIV antigens, immunogenic compositions and medicaments comprising such HIV antigens, methods and uses for such HIV antigens and immunogenic compositions and medicaments for making a α-HIV antibody, as well as a-HIV antibodies, therapeutic compositions an medicaments comprising such α-HIV antibodies, and methods and uses for such α-HIV antibodies and therapeutic compositions and medicaments for treating an HIV-based disease.
The present specification discloses HIV antigens, immunogenic compositions and medicaments comprising such HIV antigens, methods and uses for such HIV antigens and immunogenic compositions and medicaments for making a α-HIV antibody, as well as α-HIV antibodies, therapeutic compositions an medicaments comprising such α-HIV antibodies, and methods and uses for such α-HIV antibodies and therapeutic compositions and medicaments for treating an HIV-based disease.
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
C07K 16/10 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant de virus de virus à ARN
G01N 33/569 - Tests immunologiquesTests faisant intervenir la formation de liaisons biospécifiquesMatériaux à cet effet pour micro-organismes, p. ex. protozoaires, bactéries, virus
A61K 39/00 - Préparations médicinales contenant des antigènes ou des anticorps
05 - Produits pharmaceutiques, vétérinaires et hygièniques
42 - Services scientifiques, technologiques et industriels, recherche et conception
44 - Services médicaux, services vétérinaires, soins d'hygiène et de beauté; services d'agriculture, d'horticulture et de sylviculture.
45 - Services juridiques; services de sécurité; services personnels pour individus
Produits et services
Pharmaceuticals, veterinary preparations, dietetic
substances for medical use; plasters, disinfectants,
fungicides, herbicides, preparations for destroying vermin,
medications, nutritional substances for medical use and
supplements, vitamins, minerals, bacteriological
preparations; biological preparations, diagnostic
preparations, chemicals for use in the manufacture of
pharmaceuticals; vaccines. Scientific and technological services and research and
design relating thereto; research services and development
services; development of pharmaceutical formulations,
clinical scientific evaluation of pharmaceuticals, research
and development for others in the field of pharmaceuticals;
professional consulting in the field of medical research,
technical and scientific consulting services; preparation of
scientific reports; design, development, analysis, testing,
assessment, advice in the field of chemical and medical
products and services; testing and analysis of materials and
pharmaceuticals; characterisation of materials; screening
and formulation of materials and pharmaceuticals; discovery,
development and design of pharmaceutical and therapeutic
preparations; research, development and formulation of
biological and therapeutic preparations. Medical services, veterinary services, hygiene services for
human beings; medical clinics, convalescent home services,
dentistry, healthcare services, nursing homes, midwife
services, opticians services, physiotherapy services,
psychology services, blood bank services, agricultural,
horticultural and forestry services; hospice, hospital,
medical assistance, nursing, pharmacy advice, and rest home
services; surgery, assistance and advice in the fields of
sanitary, nutritional, naturopathic, allopathic,
pharmaceutical, medical and healthcare products and
services; information and advisory services relating to the
foregoing; including the provision of such services via the
Internet, by online means and/or by communications networks,
provision of information relating to pharmaceuticals, drug
delivery systems, vaccines. Licensing of intellectual property rights; licensing of
technologies in relation to medical and scientific research;
regulatory registration of pharmaceuticals and official
licensing of pharmaceutical compounds; official regulatory
assistance and advice in the fields of chemical, sanitary,
food, beverage, nutritional, naturopathic, pharmaceutical,
medical, veterinary and healthcare products and services.
Provided is a pharmaceutical agent for use in the treatment of inflammation, in a subject prone to and/or experiencing an excessive inflammatory response as a result of infection with an infectious agent and/or exposure to an allergen and/or exposure to an environmental trigger, which pharmaceutical agent comprises an agent for preventing, hindering, modulating or reducing: (a) the production, activity and/or effect of one or more cytokines; and/or (b) the functionality of one or more cells that are targets for the cytokines; and/or (c) a pathological effect caused by cells producing and/or activated by the cytokines.
C07K 16/24 - Immunoglobulines, p. ex. anticorps monoclonaux ou polyclonaux contre du matériel provenant d'animaux ou d'humains contre des cytokines, des lymphokines ou des interférons
A61K 39/395 - AnticorpsImmunoglobulinesImmunsérum, p. ex. sérum antilymphocitaire
from polypeptide sequences having 85% homology or more with one or more of the above sequences and contained in one or more of the following databases: GenBank, Protein Data Bank (PDB), SwissProt, Protein Information Resource (PIR), Protein Research Foundation (PRF), or CDS translations of these.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
Provided is a pharmaceutical agent comprising a pharmaceutically active moiety capable of transforming a sugar, preferably glucose, into a compound that is not metabolised, which pharmaceutically active moiety does not adversely affect blood composition or blood characteristics.
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
Provided is a polypeptide composition comprising one or more polypeptides, which polypeptides are immunogenic in a vertebrate such that they cause the vertebrate to produce immune system cells capable of recognising at least one epitope from an arthropod saliva protein fraction, wherein the arthropod saliva protein fraction has a mass of 4OkDA or less, and wherein the polypeptides are selected independently from: the polypeptide sequences of SEQ ID 1-44 or sub-sequences from these sequences, the subsequences having 7 amino acids or more; or from polypeptide sequences having 85% homology or more with one or more of the above sequences and contained in one or more of the following databases: GenBank, Protein Data Bank (PDB), SwissProt, Protein Information Resource (PIR), Protein Research Foundation (PRF), or CDS translations of these.
C07K 14/435 - Peptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'animauxPeptides ayant plus de 20 amino-acidesGastrinesSomatostatinesMélanotropinesLeurs dérivés provenant d'humains
Provided is a compound comprising: (a) a first component capable of binding to ER+ cell receptors; and (b) a second component; wherein the second component is a ribosome inactivating toxin and is conjugated to the first component.
A61K 47/48 - Préparations médicinales caractérisées par les ingrédients non actifs utilisés, p.ex. supports, additifs inertes l'ingrédient non actif étant chimiquement lié à l'ingrédient actif, p.ex. conjugués polymère-médicament
