1-151-151-151-15 alkynyl; or a pharmaceutically acceptable salt, solvate, metabolite, prodrug, bioisostere, or protected form thereof, for use in the treatment or prevention of a sleep disorder, together with methods of treating or preventing a sleep disorder in a subject or of treating or preventing a symptom or co-morbidity associated with a sleep disorder.
Described are compositions comprising selected isolated 4-hydroxymethyl-prolines, or pharmaceutically acceptable salts or derivatives thereof. Also described are novel 4-hydroxymethyl-N-methyl-prolines, together with processes for their preparation, compositions containing them, as well as their use as medicaments and pharmaceuticals. Also described are processes for producing a herbal medicine comprising the step of monitoring the quality of said herbal medicine by detecting the presence or absence or measuring the amount of one or more 4-hydroxymethyl-N-methyl-prolines in a sample of said herbal medicine.
C07D 207/16 - Atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
Described are compositions comprising a cyclic guanidine for use in a method of neuroprotection or for treating or preventing a GBA deficiency disease. Also described are pharmaceutical compositions comprising a cyclic guanidine and a pharmaceutically acceptable excipient, along with related methods of treating or preventing a GBA deficiency disease. Also described are various processes for producing a yogurt, or for monitoring the quality of a yogurt, comprising testing the sample for GCase activity, the presence of glycosidase modulatory activity, the presence or absence of a cyclic guanidine and/or to measure the amount of a cyclic guanidine in the sample, and/or for the presence of glycosidase modulatory activity, for example for the inhibition or promotion of one or more glycosidases.
A23C 9/123 - Préparations à base de lait fermentéTraitements utilisant des micro-organismes ou des enzymes ne comportant que des micro-organismes de la famille des lactobactériacéesYoghourt
A61K 31/4168 - 1,3-Diazoles ayant un atome d'azote lié en position 2, p. ex. clonidine
C12Q 1/34 - Procédés de mesure ou de test faisant intervenir des enzymes, des acides nucléiques ou des micro-organismesCompositions à cet effetProcédés pour préparer ces compositions faisant intervenir une hydrolase
Disclosed are processes for the production of composition comprising one or more fructose amino acids, said process comprising the steps of: (a) providing plant material derived from a botanical source selected from plants of the families Solanaceae, Compositae, (Asteraceae), Guttiferae, Umbelliferae, Papaveraceae, Vitidaceae or Acanthaceae; (b) extracting one or more fructose amino acid(s) from said plant material; and optionally (c) detecting the presence and/or measuring the amount of said fructose amino acid(s) in the extract of step (b).
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
H01J 49/00 - Spectromètres pour particules ou tubes séparateurs de particules
Described are compositions comprising a cyclic guanidine for use in a method of neuroprotection or for treating or preventing a GBA deficiency disease. Also described are pharmaceutical compositions comprising a cyclic guanidine and a pharmaceutically acceptable excipient, along with related methods of treating or preventing a GBA deficiency disease. Also described are various processes for producing a yogurt, or for monitoring the quality of a yogurt, comprising testing the sample for GCase activity, the presence of glycosidase modulatory activity, the presence or absence of a cyclic guanidine and/or to measure the amount of a cyclic guanidine in the sample, and/or for the presence of glycosidase modulatory activity, for example for the inhibition or promotion of one or more glycosidases.
A61P 25/00 - Médicaments pour le traitement des troubles du système nerveux
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A23L 5/00 - Préparation ou traitement des aliments ou produits alimentaires en généralAliments ou produits alimentaires ainsi obtenusLeurs matériaux
Described are processes for the production of a composition comprising (2R, 3R, 4R, 5S)-3, 4, 5-trihydroxypiperidine-2-carboxylic acid (idoBR1), said process comprising the steps of: a) providing plant material from a botanical source comprising plant of the family Cucurbitaceae; b) fractionating said plant material to produce an extract enriched in idoBR1 c) assaying said extract for: i) inhibitory activity against sialidase or TNF-alpha or ii) IL-10 stimulatory activity; and d) formulating said assayed extract with a cosmetically-, nutraceutically- or pharmaceutically-acceptable excipient or carrier to produce a cosmetic, nutraceutical or pharmaceutical composition.
A61K 31/45 - Pipéridines non condensées, p. ex. pipérocaïne ayant des groupes oxo liés directement à l'hétérocycle, p. ex. cycloheximide
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61Q 19/00 - Préparations pour les soins de la peau
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
Disclosed are processes for the production of composition comprising one or more fructose amino acids, and related. Such a process may comprise the steps of: (a) providing plant material derived from a botanical source selected from plants of the families Solanaceae, Compositae, Asteraceae, Guttiferae, Umbelliferae, Papaveraceae, Vitidaceae or Acanthaceae; (b) extracting one or more fructose amino acid(s) from said plant material; and optionally, (c) detecting the presence and/or measuring the amount of said fructose amino acid(s) in the extract of step (b).
A61K 36/00 - Préparations médicinales de constitution indéterminée contenant du matériel provenant d'algues, de lichens, de champignons, ou de plantes, ou leurs dérivés, p. ex. médicaments traditionnels à base de plantes
G01N 33/68 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des protéines, peptides ou amino-acides
H01J 49/00 - Spectromètres pour particules ou tubes séparateurs de particules
Described are processes for the production of a composition comprising (2R,3R,4R,5S)- 3,4,5-trihydroxypiperidine-2-carboxylic acid (idoBR1), said process comprising the steps of: (a) providing plant material from a botanical source comprising plants of the family Cucurbitaceae; (b) fractionating said plant material to produce an extract enriched in idoBR1; (c) assaying said extract for: (i) inhibitory activity against sialidase or TNF-alpha; or (ii) IL-10 stimulatory activity; and (d) formulating said assayed extract with a cosmetically-, nutraceutically- or pharmaceutically-acceptable excipient or carrier to produce a cosmetic, nutraceutical or pharmaceutical composition.
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61K 31/445 - Pipéridines non condensées, p. ex. pipérocaïne
Described are compositions comprising selected isolated 4-hydroxymethyl-prolines, or pharmaceutically acceptable salts or derivatives thereof. Also described are novel 4- hydroxymethyl-N-methyl-prolines, together with processes for their preparation, compositions containing them, as well as their use as medicaments and pharmaceuticals. Also described are processes for producing a herbal medicine comprising the step of monitoring the quality of said herbal medicine by detecting the presence or absence or measuring the amount of one or more 4-hydroxymethyl-N-methyl-prolines in a sample of said herbal medicine.
A61K 31/401 - ProlineSes dérivés, p. ex. captopril
A61P 3/00 - Médicaments pour le traitement des troubles du métabolisme
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
A61P 37/00 - Médicaments pour le traitement des troubles immunologiques ou allergiques
05 - Produits pharmaceutiques, vétérinaires et hygièniques
30 - Aliments de base, thé, café, pâtisseries et confiseries
Produits et services
Food supplements; nutritional supplements; food supplements containing iminosugars; nutritional supplements containing iminosugars [ ; plant extracts containing iminosugars for medicinal, veterinary and pharmaceutical use; plant extracts for regulating blood sugar; plant extracts for regulating skin sugars for medical, veterinary and pharmaceutical purposes; plant extracts for controlling inflammation for medical, veterinary and pharmaceutical purposes; compositions containing iminosugars for improving cellular function for medical and veterinary use; compositions containing iminosugars for improving removal of toxins for medical and veterinary use ] , all of the aforementioned goods containing iminosugars Honey containing iminosugars
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
05 - Produits pharmaceutiques, vétérinaires et hygièniques
Produits et services
Chemical substances containing iminosugars for use as food and beverage ingredients; plant extracts containing iminosugars for use in the manufacture of food and beverages; compositions containing iminosugars for improving cellular function (other than for medical and veterinary use); compositions containing iminosugars for improving removal of toxins (other than for medical and veterinary use). Food supplements; nutritional supplements; food supplements containing iminosugars; nutritional supplements containing iminosugars; plant extracts containing iminosugars for medicinal, veterinary and pharmaceutical use; plant extracts for regulating blood sugar; plant extracts for regulating skin sugars; plant extracts for controlling inflammation; compositions containing iminosugars for improving cellular function for medical and veterinary use; compositions containing iminosugars for improving removal of toxins for medical and veterinary use.
Compositions comprising isolated ido-BR1 are described for use in therapy or prophylaxis, including the treatment of inflammatory diseases (for example as anti-inflammatory drugs) and to reduce inflammation. Also described are methods for monitoring the quality of a Cucurbitaceae extract, to processes for producing a Cucurbitaceae extract as well as to Cucurbitaceae extracts obtainable by such processes.
C07D 211/60 - Atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A61Q 19/00 - Préparations pour les soins de la peau
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61Q 19/10 - Préparations pour le nettoyage ou le bain
G01N 33/94 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des narcotiques
A23L 33/105 - Extraits de plantes, leurs doublons artificiels ou leurs dérivés
A61K 9/00 - Préparations médicinales caractérisées par un aspect particulier
01 - Produits chimiques destinés à l'industrie, aux sciences ainsi qu'à l'agriculture
Produits et services
Chemical compositions and materials containing iminosugars for use in cosmetics; plant extracts containing iminosugars for use in the manufacture of cosmetics; chemical substances containing iminosugars for use as food and beverage ingredients; plant extracts containing iminosugars for use in the manufacture of food and beverages; compositions containing iminosugars for improving cellular function (other than for medical and veterinary use); compositions containing iminosugars for improving removal of toxins (other than for medical and veterinary use).
Processes for the production of a composition comprising material derived from seeds of plants of the genus Oryza, the process comprise the steps of:(a)providing material derived from seeds of the genus Oryza; and(b)determining the presence or absence and/or measuring the amount of at least one iminosugar in the material of step (a). Also described is the use of material derived from seeds of plants of the genus Oryza, which material comprises at least one iminosugar, as a food or feed supplement for lowering the glycaemic index (GI) value of said food or feed.
Compositions comprising isolated ido-BR1 are described for use in therapy or prophylaxis, including the treatment of inflammatory diseases (for example as anti-inflammatory drugs) and to reduce inflammation. Also described are methods for monitoring the quality of a Cucurbitaceae extract, to processes for producing a Cucurbitaceae extract as well as to Cucurbitaceae extracts obtainable by such processes.
A61K 31/445 - Pipéridines non condensées, p. ex. pipérocaïne
A61Q 19/00 - Préparations pour les soins de la peau
G01N 33/94 - Analyse chimique de matériau biologique, p. ex. de sang ou d'urineTest par des méthodes faisant intervenir la formation de liaisons biospécifiques par ligandsTest immunologique faisant intervenir des narcotiques
C07D 211/60 - Atomes de carbone comportant trois liaisons à des hétéro-atomes, avec au plus une liaison à un halogène, p. ex. radicaux ester ou nitrile
A61K 8/49 - Cosmétiques ou préparations similaires pour la toilette caractérisés par la composition contenant des composés organiques contenant des composés hétérocycliques
A23L 1/30 - contenant des additifs (A23L 1/308 a priorité);;
A61K 45/06 - Mélanges d'ingrédients actifs sans caractérisation chimique, p. ex. composés antiphlogistiques et pour le cœur
A61Q 19/10 - Préparations pour le nettoyage ou le bain
Disclosed are processes for the production of composition comprising one or more fructose amino acids, said process comprising the steps of: (a) providing plant material derived from a botanical source selected from plants of the families Solanaceae, Compositae, (Asteraceae), Guttiferae, Umbelliferae, Papaveraceae, Vitidaceae or Acanthaceae; (b) extracting one or more fructose amino acid(s) from said plant material; and optionally (c) detecting the presence and/or measuring the amount of said fructose amino acid(s) in the extract of step (b).
A61K 36/23 - Apiaceae ou Umbelliferae (famille de la carotte), p. ex. aneth, cerfeuil, coriandre ou cumin
A61K 36/28 - Asteraceae ou Compositae (famille de l'aster ou du tournesol), p. ex. camomille, chrysanthème matricaire, achillée ou echinacée
A61K 36/38 - Clusiaceae, Hypericaceae ou Guttiferae (famille de l'Hypericum ou du mangoustan), p. ex. millepertuis
A61K 36/66 - Papaveraceae (famille du pavot), p. ex. sanguinaire du Canada
A61P 25/28 - Médicaments pour le traitement des troubles du système nerveux des troubles dégénératifs du système nerveux central, p. ex. agents nootropes, activateurs de la cognition, médicaments pour traiter la maladie d'Alzheimer ou d'autres formes de démence
A61P 3/10 - Médicaments pour le traitement des troubles du métabolisme de l'homéostase du glucose de l'hyperglycémie, p. ex. antidiabétiques
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
Composition comprising isolated ido-BR1 are described for use in therapy or prophylaxis, including the treatment of inflammatory diseases. (for example as anti-inflammatory drugs) and to reduce inflammation. Also described are methods for monitoring the quality of a Cucurbitaceae extract, to processes for producing a Cucurbitaceae extract as well as to Cucurbitaceae extracts obtainable by such processes.
A61P 29/00 - Agents analgésiques, antipyrétiques ou anti-inflammatoires non centraux, p. ex. agents antirhumatismauxMédicaments anti-inflammatoires non stéroïdiens [AINS]
42 - Services scientifiques, technologiques et industriels, recherche et conception
Produits et services
Laboratory services for the detection, isolation and extraction of novel plant extracts and compounds; the analysis of plant extracts and compounds; research, development, design and testing for others of plant extracts; technical advice and consultation services in the field of novel plant extracts; none of the aforesaid being services in relation to the fragrance and flavours industries.
